| 1. |
- Lind, Lars, et al.
(författare)
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Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- 2021
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Ingår i: eLife. - : eLife Sciences Publications Ltd. - 2050-084X. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
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| 2. |
- Bryazka, D., et al.
(författare)
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Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020
- 2022
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Ingår i: Lancet. - 0140-6736. ; 400:10347, s. 185-235
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Tidskriftsartikel (refereegranskat)abstract
- Background The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. Methods For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15-95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol. Findings The burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15-39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0-0) and 0.603 (0.400-1.00) standard drinks per day, and the NDE varied between 0.002 (0-0) and 1.75 (0.698-4.30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0.114 (0-0.403) to 1.87 (0.500-3.30) standard drinks per day and an NDE that ranged between 0.193 (0-0.900) and 6.94 (3.40-8.30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59.1% (54.3-65.4) were aged 15-39 years and 76.9% (7.0-81.3) were male. Interpretation There is strong evidence to support recommendations on alcohol consumption varying by age and location. Stronger interventions, particularly those tailored towards younger individuals, are needed to reduce the substantial global health loss attributable to alcohol. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.
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| 3. |
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| 4. |
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| 5. |
- Kinyoki, DK, et al.
(författare)
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Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
- 2020
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Ingår i: Nature medicine. - : Springer Science and Business Media LLC. - 1546-170X .- 1078-8956. ; 26:5, s. 750-759
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Tidskriftsartikel (refereegranskat)abstract
- A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic.
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| 6. |
- Frostad, J. J., et al.
(författare)
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Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000-18: a geospatial modelling study
- 2022
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Ingår i: Lancet Global Health. - 2214-109X. ; 10:10
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Tidskriftsartikel (refereegranskat)abstract
- Background More than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local patterns in cooking vary systematically, subnational trends in use of solid fuels have yet to be comprehensively analysed. We estimated the prevalence of solid-fuel use with high spatial resolution to explore subnational inequalities, assess local progress, and assess the effects on health in low-income and middle-income countries (LMICs) without universal access to clean fuels. Methods We did a geospatial modelling study to map the prevalence of solid-fuel use for cooking at a 5 km x 5 km resolution in 98 LMICs based on 2.1 million household observations of the primary cooking fuel used from 663 population-based household surveys over the years 2000 to 2018. We use observed temporal patterns to forecast household air pollution in 2030 and to assess the probability of attaining the Sustainable Development Goal (SDG) target indicator for clean cooking. We aligned our estimates of household air pollution to geospatial estimates of ambient air pollution to establish the risk transition occurring in LMICs. Finally, we quantified the effect of residual primary solid-fuel use for cooking on child health by doing a counterfactual risk assessment to estimate the proportion of deaths from lower respiratory tract infections in children younger than 5 years that could be associated with household air pollution. Findings Although primary reliance on solid-fuel use for cooking has declined globally, it remains widespread. 593 million people live in districts where the prevalence of solid-fuel use for cooking exceeds 95%. 66% of people in LMICs live in districts that are not on track to meet the SDG target for universal access to clean energy by 2030. Household air pollution continues to be a major contributor to particulate exposure in LMICs, and rising ambient air pollution is undermining potential gains from reductions in the prevalence of solid-fuel use for cooking in many countries. We estimated that, in 2018, 205000 (95% uncertainty interval 147000-257000) children younger than 5 years died from lower respiratory tract infections that could be attributed to household air pollution. Interpretation Efforts to accelerate the adoption of clean cooking fuels need to be substantially increased and recalibrated to account for subnational inequalities, because there are substantial opportunities to improve air quality and avert child mortality associated with household air pollution. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.
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| 7. |
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| 8. |
- Sbarra, AN, et al.
(författare)
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Mapping routine measles vaccination in low- and middle-income countries
- 2021
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 589:7842, s. 415-
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Tidskriftsartikel (refereegranskat)abstract
- The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 × 5-km2pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children.
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| 9. |
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| 10. |
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| 11. |
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| 12. |
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| 13. |
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| 14. |
- Abbafati, Cristiana, et al.
(författare)
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- 2020
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Tidskriftsartikel (refereegranskat)
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| 15. |
- Bergman, A. S., et al.
(författare)
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280 GHz Focal Plane Unit Design and Characterization for the SPIDER-2 Suborbital Polarimeter
- 2018
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Ingår i: Journal of Low Temperature Physics. - : Springer Science and Business Media LLC. - 0022-2291 .- 1573-7357. ; 193:5-6, s. 1075-1084
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Tidskriftsartikel (refereegranskat)abstract
- We describe the construction and characterization of the 280 GHz bolometric focal plane units (FPUs) to be deployed on the second flight of the balloon-borne SPIDER instrument. These FPUs are vital to SPIDER's primary science goal of detecting or placing an upper limit on the amplitude of the primordial gravitational wave signature in the cosmic microwave background (CMB) by constraining the B-mode contamination in the CMB from Galactic dust emission. Each 280 GHz focal plane contains a 16 x 16 grid of corrugated silicon feedhorns coupled to an array of aluminum-manganese transition-edge sensor (TES) bolometers fabricated on 150 mm diameter substrates. In total, the three 280 GHz FPUs contain 1530 polarization-sensitive bolometers (765 spatial pixels) optimized for the low loading environment in flight and read out by time-division SQUID multiplexing. In this paper, we describe the mechanical, thermal, and magnetic shielding architecture of the focal planes and present cryogenic measurements which characterize yield and the uniformity of several bolometer parameters. The assembled FPUs have high yields, with one array as high as 95% including defects from wiring and readout. We demonstrate high uniformity in device parameters, finding the median saturation power for each TES array to be similar to 3 pW at 300 mK with a less than 6% variation across each array at 1 sigma. These focal planes will be deployed alongside the 95 and 150 GHz telescopes in the SPIDER-2 instrument, slated to fly from McMurdo Station in Antarctica in December 2018.
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| 16. |
- Leung, J. S.-Y., et al.
(författare)
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A Simulation-based Method for Correcting Mode Coupling in CMB Angular Power Spectra
- 2022
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 928:2
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Tidskriftsartikel (refereegranskat)abstract
- Modern cosmic microwave background (CMB) analysis pipelines regularly employ complex time-domain filters, beam models, masking, and other techniques during the production of sky maps and their corresponding angular power spectra. However, these processes can generate couplings between multipoles from the same spectrum and from different spectra, in addition to the typical power attenuation. Within the context of pseudo-C-l based, MASTER-style analyses, the net effect of the time-domain filtering is commonly approximated by a multiplicative transfer function, F-l , that can fail to capture mode mixing and is dependent on the spectrum of the signal. To address these shortcomings, we have developed a simulation-based spectral correction approach that constructs a two-dimensional transfer matrix, J(ll'), which contains information about mode mixing in addition to mode attenuation. We demonstrate the application of this approach on data from the first flight of the Spider balloon-borne CMB experiment.
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| 17. |
- Ade, P. A. R., et al.
(författare)
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A Constraint on Primordial B-modes from the First Flight of the Spider Balloon-borne Telescope
- 2022
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 927:2
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Tidskriftsartikel (refereegranskat)abstract
- We present the first linear polarization measurements from the 2015 long-duration balloon flight of SPIDER, which is an experiment that is designed to map the polarization of the cosmic microwave background (CMB) on degree angular scales. The results from these measurements include maps and angular power spectra from observations of 4.8% of the sky at 95 and 150 GHz, along with the results of internal consistency tests on these data. While the polarized CMB anisotropy from primordial density perturbations is the dominant signal in this region of sky, Galactic dust emission is also detected with high significance. Galactic synchrotron emission is found to be negligible in the SPIDER bands. We employ two independent foreground-removal techniques to explore the sensitivity of the cosmological result to the assumptions made by each. The primary method uses a dust template derived from Planck data to subtract the Galactic dust signal. A second approach, which constitutes a joint analysis of SPIDER and Planck data in the harmonic domain, assumes a modified-blackbody model for the spectral energy distribution of the dust with no constraint on its spatial morphology. Using a likelihood that jointly samples the template amplitude and r parameter space, we derive 95% upper limits on the primordial tensor-to-scalar ratio from Feldman-Cousins and Bayesian constructions, finding r < 0.11 and r < 0.19, respectively. Roughly half the uncertainty in r derives from noise associated with the template subtraction. New data at 280 GHz from SPIDER´s second flight will complement the Planck polarization maps, providing powerful measurements of the polarized Galactic dust emission.
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| 18. |
- Filippini, J. P., et al.
(författare)
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In-Flight Gain Monitoring of SPIDER's Transition-Edge Sensor Arrays
- 2022
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Ingår i: Journal of Low Temperature Physics. - : Springer Science and Business Media LLC. - 0022-2291 .- 1573-7357. ; 209:3-4, s. 649-657
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Tidskriftsartikel (refereegranskat)abstract
- Experiments deploying large arrays of transition-edge sensors (TESs) often require a robust method to monitor gain variations with minimal loss of observing time. We propose a sensitive and non-intrusive method for monitoring variations in TES responsivity using small square waves applied to the TES bias. We construct an estimator for a TES's small-signal power response from its electrical response that is exact in the limit of strong electrothermal feedback. We discuss the application and validation of this method using flight data from SPIDER, a balloon-borne telescope that observes the polarization of the cosmic microwave background with more than 2000 TESs. This method may prove useful for future balloon- and space-based instruments, where observing time and ground control bandwidth are limited.
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| 19. |
- Gambrel, A. E., et al.
(författare)
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The XFaster Power Spectrum and Likelihood Estimator for the Analysis of Cosmic Microwave Background Maps
- 2021
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 922:2
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Tidskriftsartikel (refereegranskat)abstract
- We present the XFaster analysis package, a fast, iterative angular power spectrum estimator based on a diagonal approximation to the quadratic Fisher matrix estimator. It uses Monte Carlo simulations to compute noise biases and filter transfer functions and is thus a hybrid of both Monte Carlo and quadratic estimator methods. In contrast to conventional pseudo-Cℓ–based methods, the algorithm described here requires a minimal number of simulations and does not require them to be precisely representative of the data to estimate accurate covariance matrices for the bandpowers. The formalism works with polarization-sensitive observations and also data sets with identical, partially overlapping, or independent survey regions. The method was first implemented for the analysis of BOOMERanG data and also used as part of the Planck analysis. Here we describe the full, publicly available analysis package, written in Python, as developed for the analysis of data from the 2015 flight of the Spider instrument. The package includes extensions for self-consistently estimating null spectra and estimating fits for Galactic foreground contributions. We show results from the extensive validation of XFaster using simulations and its application to the Spider data set.
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| 20. |
- Gualtieri, R., et al.
(författare)
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SPIDER : CMB Polarimetry from the Edge of Space
- 2018
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Ingår i: Journal of Low Temperature Physics. - : Springer Science and Business Media LLC. - 0022-2291 .- 1573-7357. ; 193:5-6, s. 1112-1121
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Tidskriftsartikel (refereegranskat)abstract
- SPIDER is a balloon-borne instrument designed to map the polarization of the millimeter-wave sky at large angular scales. Spider targets the B-mode signature of primordial gravitational waves in the cosmic microwave background (CMB), with a focus on mapping a large sky area with high fidelity at multiple frequencies. SPIDER's first long-duration balloon (LDB) flight in January 2015 deployed a total of 2400 antenna-coupled transition-edge sensors (TESs) at 90 GHz and 150 GHz. In this work we review the design and in-flight performance of the SPIDER instrument, with a particular focus on the measured performance of the detectors and instrument in a space-like loading and radiation environment. SPIDER's second flight in December 2018 will incorporate payload upgrades and new receivers to map the sky at 285 GHz, providing valuable information for cleaning polarized dust emission from CMB maps.
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| 21. |
- Nagy, J. M., et al.
(författare)
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A New Limit on CMB Circular Polarization from SPIDER
- 2017
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 844:2
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Tidskriftsartikel (refereegranskat)abstract
- We present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from SPIDER's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the range 33 < l < 307. No other limits exist over this full range of angular scales, and SPIDER improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on l (l + 1)C-l(VV) /(2 pi) ranging from 141 to 255 mu K-2 at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.
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| 22. |
- Osherson, B., et al.
(författare)
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Particle Response of Antenna-Coupled TES Arrays : Results from SPIDER and the Laboratory
- 2020
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Ingår i: Journal of Low Temperature Physics. - : Springer Science and Business Media LLC. - 0022-2291 .- 1573-7357. ; 199:3-4, s. 1127-1136
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Tidskriftsartikel (refereegranskat)abstract
- Future mm-wave and sub-mm space missions will employ large arrays of multiplexed transition-edge-sensor (TES) bolometers. Such instruments must contend with the high flux of cosmic rays beyond our atmosphere that induce 'glitches' in bolometer data, which posed a challenge to data analysis from the Planck bolometers. Future instruments will face the additional challenges of shared substrate wafers and multiplexed readout wiring. In this work, we explore the susceptibility of modern TES arrays to the cosmic ray environment of space using two data sets: the 2015 long-duration balloon flight of the SPIDER cosmic microwave background polarimeter, and a laboratory exposure of SPIDER flight hardware to radioactive sources. We find manageable glitch rates and short glitch durations, leading to minimal effect on SPIDER analysis. We constrain energy propagation within the substrate through a study of multi-detector coincidences and give a preliminary look at pulse shapes in laboratory data.
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| 23. |
- Polme, S., et al.
(författare)
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FungalTraits: a user-friendly traits database of fungi and fungus-like stramenopiles
- 2020
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Ingår i: Fungal Diversity. - : Springer Science and Business Media LLC. - 1560-2745 .- 1878-9129. ; 105:1, s. 1-16
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Tidskriftsartikel (refereegranskat)abstract
- The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies. Over the past decades, rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats. Yet, in spite of the progress of molecular methods, knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging. In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels. Combining the information from previous efforts such as FUNGuild and Fun(Fun) together with involvement of expert knowledge, we reannotated 10,210 and 151 fungal and Stramenopila genera, respectively. This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera, designed for rapid functional assignments of environmental studies. In order to assign the trait states to fungal species hypotheses, the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences. On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1% dissimilarity threshold.
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| 24. |
- Amiri, M., et al.
(författare)
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Periodic activity from a fast radio burst source
- 2020
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 582:7812, s. 351-355
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Tidskriftsartikel (refereegranskat)abstract
- Fast radio bursts (FRBs) are bright, millisecond-duration radio transients originating from sources at extragalactic distances1, the origin of which is unknown. Some FRB sources emit repeat bursts, ruling out cataclysmic origins for those events2–4. Despite searches for periodicity in repeat burst arrival times on timescales from milliseconds to many days2,5–7, these bursts have hitherto been observed to appear sporadically and—although clustered8—without a regular pattern. Here we report observations of a 16.35 ± 0.15 day periodicity (or possibly a higher-frequency alias of that periodicity) from the repeating FRB 180916.J0158+65 detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst Project4,9. In 38 bursts recorded from 16 September 2018 to 4 February 2020 utc, we find that all bursts arrive in a five-day phase window, and 50 per cent of the bursts arrive in a 0.6-day phase window. Our results suggest a mechanism for periodic modulation either of the burst emission itself or through external amplification or absorption, and disfavour models invoking purely sporadic processes.
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| 25. |
- Gensicke, H., et al.
(författare)
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Intravenous thrombolysis and platelet count
- 2018
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Ingår i: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 0028-3878 .- 1526-632X. ; 90:8
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveTo study the effect of platelet count (PC) on bleeding risk and outcome in stroke patients treated with IV thrombolysis (IVT) and to explore whether withholding IVT in PC < 100 x 10(9)/L is supported.MethodsIn this prospective multicenter, IVT register-based study, we compared PC with symptomatic intracranial hemorrhage (sICH; Second European-Australasian Acute Stroke Study [ECASS II] criteria), poor outcome (modified Rankin Scale score 3-6), and mortality at 3 months. PC was used as a continuous and categorical variable distinguishing thrombocytopenia (<150 x 10(9)/L), thrombocytosis (>450 x 10(9)/L), and normal PC (150-450 x 10(9)/L [reference group]). Moreover, PC < 100 x 10(9)/L was compared to PC 100 x 10(9)/L. Unadjusted and adjusted odds ratios (ORs) with 95% confidence intervals (CIs) from the logistic regression models were calculated.ResultsAmong 7,533 IVT-treated stroke patients, 6,830 (90.7%) had normal PC, 595 (7.9%) had thrombocytopenia, and 108 (1.4%) had thrombocytosis. Decreasing PC (every 10 x 10(9)/L) was associated with increasing risk of sICH (ORadjusted 1.03, 95% CI 1.02-1.05) but decreasing risk of poor outcome (ORadjusted 0.99, 95% CI 0.98-0.99) and mortality (ORadjusted 0.98, 95% CI 0.98-0.99). The risk of sICH was higher in patients with thrombocytopenic than in patients with normal PC (ORadjusted 1.73, 95% CI 1.24-2.43). However, the risk of poor outcome (ORadjusted 0.89, 95% CI 0.39-1.97) and mortality (ORadjusted 1.09, 95% CI 0.83-1.44) did not differ significantly. Thrombocytosis was associated with mortality (ORadjusted 2.02, 95% CI 1.21-3.37). Forty-four (0.3%) patients had PC < 100 x 10(9)/L. Their risks of sICH (ORunadjusted 1.56, 95% CI 0.48-5.07), poor outcome (ORadjusted 1.63, 95% CI 0.82-3.24), and mortality (ORadjusted 1.38, 95% CI 0.64-2.98) did not differ significantly from those of patients with PC 100 x 10(9)/L.ConclusionLower PC was associated with increased risk of sICH, while higher PC indicated increased mortality. Our data suggest that PC modifies outcome and complications in individual patients, while withholding IVT in all patients with PC < 100 x 10(9)/L is challenged.
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| 26. |
- Akbarian, S, et al.
(författare)
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The PsychENCODE project
- 2015
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Ingår i: Nature neuroscience. - : Springer Science and Business Media LLC. - 1546-1726 .- 1097-6256. ; 18:12, s. 1707-1712
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Tidskriftsartikel (refereegranskat)
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| 27. |
- Amiri-Mosavi, A, et al.
(författare)
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Expression of cholecystokinin-B/gastrin receptors in medullary thyroid cancer.
- 1999
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Ingår i: The European journal of surgery = Acta chirurgica. - : Oxford University Press (OUP). - 1102-4151. ; 165:7, s. 628-31
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Tidskriftsartikel (refereegranskat)abstract
- To characterise the cholecystokinin (CCK) receptor subtypes in medullary thyroid cancer by measuring the expression of CCK-A and CCK-B/gastrin receptor mRNA.
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| 28. |
- Meghdadi, S., et al.
(författare)
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Synthesis, X-ray crystal structure, and electrochemistry of copper(II) complexes of a new tridentate unsymmetrical Schiff base ligand and its hydrolytically rearranged isomer
- 2012
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Ingår i: Inorganica Chimica Acta. - : Elsevier BV. - 0020-1693. ; 385, s. 31-38
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Tidskriftsartikel (refereegranskat)abstract
- A new unsymmetrical Schiff base ligand HL1, HBacabza, and its copper(II) complexes [Cu2L21(OAc)(2)] (1) and [Cu2L22(N-3)(2)]center dot 2H(2)O (2) with HBacabza = 3-(2- aminobenzylimino)-1-phenylbutan-1-one as HL1 and its hydrolytically rearranged isomer 3-(2-aminomethylphenyleneimino)-1-phenylbutan-1-one as HL2, have been synthesized and characterized by elemental analyses and spectroscopic methods. The rearrangement of HL1 to HL2 occurs in a hydrolysis-recondensation process in the reaction of HL1 with Cu(ClO4)(2)center dot 6H(2)O and NaN3. The crystal structures of the ligand and its complexes have been determined by single crystal X-ray diffraction. The deprotonated Bacabza coordinates to the metal center as a tridentate ligand. The acetate anion coordinates through one oxygen atom in complex 1 leading to a mono-atomic acetate oxygen-bridging dimeric copper(II) complex. Similarly, the azide anion coordinates through one nitrogen atom in complex 2 leading to a mono-atomic azide nitrogen-bridging dimeric copper(II) complex. The copper(II) ions adopt a distorted square pyramidal (4 + 1) coordination in these two complexes. The cyclic voltammetric studies of these complexes in N, N-dimethylformamide indicate that the reduction process corresponding to Cu-II/Cu-I is electrochemically irreversible in complex 1, presumably due to the structural changes during the course of redox reaction, and quasi-reversible in complex 2.
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| 29. |
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| 30. |
- Syvänen, A-C, et al.
(författare)
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A chimeric disposition of the elongation factor genes in Rickettsia prowazekii
- 1996
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Ingår i: JOURNAL OF BACTERIOLOGY. - 0021-9193. ; 178:21, s. 6192-6199
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- An exceptional disposition of the elongation factor genes is observed in Rickettsia prowazekii, in which there is only one tuf gene, which is distant from the lone firs gene, In contrast, the closely related bacterium Agrobacterium tumefaciens has the nor
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| 31. |
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| 32. |
- Alioua, A., et al.
(författare)
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Incentive mechanism for competitive edge caching in 5G-enabled Internet of things
- 2022
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Ingår i: Computer Networks. - : Elsevier BV. - 1389-1286 .- 1872-7069. ; 213
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Tidskriftsartikel (refereegranskat)abstract
- The fifth generation (5G) of cellular networks provides the enabling environment for the Internet of Things (IoT) applications. Hence, the vast proliferation of 5G-enabled IoT devices and services led to an overwhelming growth of data traffic that could saturate the core network's backhaul links. Nowadays, caching is an unavoidable technique to solve this issue, whereby popular contents are stored on edge nodes near to end-users. There exist several initiatives to motivate caching actors for improving the caching process, but not designed for the real-world competitive caching market. In this work, we propose an incentive caching strategy in a 5G-enabled IoT network by considering a completely competitive caching scenario with multiple 5G mobile network operators (MNOs) and multiple content providers (CPs). The MNOs manage a set of edge caches on their base stations and they are competing to fill these caching resources, while the CPs detain a set of popular contents and are in conflict to rent the MNOs’ caches. Each MNO aims to maximize its monetary profit and offload its backhaul links, as each CP aims to improve the quality of experience (QoE) of its end-users. Then, we formulate a multi-leader multi-follower Stackelberg game to model the interaction between MNOs and CPs and define the different players’ utilities. Subsequently, we propose an iterative algorithm based on the convex optimization method to investigate the Stackelberg equilibrium. Finally, the numerical results of the different experimentations demonstrate that our game-based incentive strategy can significantly alleviate the backhaul links while improving the user QoE.
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| 33. |
- Amiri, A., et al.
(författare)
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A replacement model to simulate the nonlinear dynamics of electro-responsive liquid crystal coatings
- 2023
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Ingår i: AIP Advances. - : AIP Publishing. - 2158-3226. ; 13:3
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Tidskriftsartikel (refereegranskat)abstract
- An electric circuit replacement model is proposed to simulate the key nonlinear dynamics of electro-responsive liquid crystal polymer networks (LCNs). LCNs are known for having great potential to be integrated into smart functional surfaces due to their ability to generate various surface patterns. However, due to their complex molecular dynamics, low-order dynamic models that can accurately describe and predict their dynamic behavior are still lacking. In light of this research gap, we develop a lumped-parameter replacement model based on the observed dynamics in the experimental data and the physics of LCN dielectric properties. The unique assembly of lumped parameters in its simplest form describes the transformation of a high-frequency input voltage to a relatively slow increase in the local height of the LCN coating in between the electrodes, serving as an excitation mechanism to induce height change. The nonlinear dynamics of this height increase, as a function of both excitation frequency and voltage, is described by the proposed model. Furthermore, the comparison of the simulation results with the experimental data from LCN shows that key LCN response characteristics are captured well by the model. This model makes it possible to accurately predict and control the response of the electro-responsive LCN surfaces to obtain a predefined desired deformation pattern, which is a vital requirement for integrating them in haptic and smart surface devices.
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| 34. |
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| 35. |
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| 36. |
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| 37. |
- Amiri, N., et al.
(författare)
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VLBA SiO maser observations of the OH/IR star OH 44.8-2.3: magnetic field and morphology
- 2012
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Ingår i: Proceedings of the International Astronomical Union. - 1743-9213 .- 1743-9221. ; 8:5287, s. 54-58
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Konferensbidrag (refereegranskat)abstract
- We report on Very Long Baseline Array SiO maser observations of the OH/IR star OH 44.8 - 2.3. The observations show that the maser features form a ring located at a distance of 5.4 AU around the central star. The masers show high fractional linear polarization up to 100%. The polarization vectors are consistent with a dipole field morphology. Additionally, we report a tentative detection of circular polarization of 7% for the brightest maser feature. This indicates a magnetic field of 1.5 ± 0.3 G. The SiO masers and the 1612 MHz OH masers suggest a mildly preferred outflow direction in the circumstellar environment of this star. The observed polarization is consistent with magnetic field structures along the preferred outflow direction. This could indicate the possible role of the magnetic fields in shaping the circumstellar environment of this object.
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| 38. |
- Amiri, N., et al.
(författare)
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VLBA SiO maser observations of the OH/IR star OH 44.8-2.3: magnetic field and morphology
- 2012
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 538
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Tidskriftsartikel (refereegranskat)abstract
- Context. SiO maser emission occurs in the extended atmosphere of evolved stars and can be studied at high angular resolution. As compact, high-brightness components they can be used as important tracers of the dynamics at distances close to the central star. The masers also serve as probes of the evolutionary path from spherically symmetric AGB stars to aspherical PNe. Very long baseline interferometry (VLBI) observations of Mira variables indicate that SiO masers are significantly linearly polarized with linear polarization fractions up to 100%. However, no information is available at high angular resolution for SiO masers in higher mass loss OH/IR stars. Theory indicates a different SiO pumping mechanism in higher mass loss evolved stars.Aims. We extend the VLBI SiO maser studies to OH/IR stars. The observations enable us to understand the SiO pumping mechanisms in higher mass-loss evolved objects and to compare them with Mira variables. Additionally, polarimetric observations of SiO masers help us to understand the magnetic field strength and morphology and to distinguish between conflicting polarization theories.Methods. The 43 GHz SiO maser observations of the OH/IR star OH 44.8-2.3 were performed with the VLBA in full polarization spectral line mode. Auxiliary EVLA observations were performed to allow for the absolute calibration of the polarization angle. The Zeeman splitting was measured by cross correlating the right and left circular polarization spectra, as well as the S-curve fitting. Additionally, we analyzed the 1612 MHz OH maser observations of OH 44.8-2.3 from the VLA archive.Results. The SiO masers of OH 44.8-2.2 form a ring located at ~5.4 AU around the star. The masers appear to be highly linearly polarized with fractional linear polarization up to 100%. The linear polarization vectors are consistent with a dipole field morphology in this star. We report a tentative detection of circular polarization of ~0.7% for the brightest maser feature. The magnetic field measured for this feature corresponds to 1.5 ± 0.3 G. Additionally, the distribution of the 1612 MHz OH maser emission could indicate an elongated morphology.Conclusions. The SiO masers in OH 44.8-2.3 exhibit a ring morphology. Even though the central AGB star of OH 44.8-2.3 is expected to be larger than typical Mira variables, the SiO masers occur at a similar distance from the stellar photosphere as Mira variables. The SiO masers and the 1612 MHz OH maser emission suggest a mildly preferred direction of the outflow in the CSE of this star. Significant linear polarization is measured for the SiO region of this star, which could develop from either collisional or radiative pumping. In either case, the observed polarization is also consistent with magnetic field structures along the preferred outflow direction. This could reflect the possible role of the magnetic field in shaping the circumstellar environment of this object. Although we cannot firmly distinguish between the different polarization theories, the derived magnetic field strength assuming standard Zeeman emission is fully consistent with other maser polarization measurements.
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| 39. |
- Amiri, V., et al.
(författare)
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Groundwater quality evaluation using Shannon information theory and human health risk assessment in Yazd province, central plateau of Iran
- 2020
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Ingår i: Environmental Science and Pollution Research. - : Springer. - 0944-1344 .- 1614-7499.
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Tidskriftsartikel (refereegranskat)abstract
- This study aims to evaluate the quality of groundwater in the most arid province of Iran, Yazd. It is highly dependent on groundwater resources to meet the domestic, industrial, and agricultural water demand. Position of water samples on the modified Gibbs diagram demonstrates that the interaction with silicates and the increase in direct cation exchange are responsible for the increased salinity of groundwater. Based on entropy theory, the decreasing order of importance of variables in controlling groundwater chemistry is Fe > As > Ba > Hg > NO2 > Pb > K > Cl > Na > Mg > SO4 > NO3 > HCO3 > Ca. The results of entropy weighted water quality index (EWWQI) calculation show that about 34 and 32% of 206 samples in the wet and dry seasons, respectively, are classified as extremely poor quality (ranks 4 and 5). Approximately 60 and 55% of 206 samples in wet and dry seasons, respectively, have excellent, good, and medium quality (ranks 1, 2, and 3). The non-carcinogenic human health risk (NHHR) from intake and dermal contact pathways using deterministic approach show that 36 and 17 samples in both seasons are not suitable for drinking by children. Furthermore, 9 and 2 samples are not suitable for drinking by adults. The results show that children are more vulnerable than adults to these health risks. The non-carcinogenic risks through dermal contact were negligible.
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| 40. |
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| 41. |
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| 42. |
- Frank, A. Carolin, et al.
(författare)
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Genome deterioration : Loss of repeated sequences and accumulation of junk DNA
- 2002
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Ingår i: Genetica. - 0016-6707 .- 1573-6857. ; 115:1, s. 1-12
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Tidskriftsartikel (refereegranskat)abstract
- A global survey of microbial genomes reveals a correlation between genome size, repeat content and lifestyle. Free-living bacteria have large genomes with a high content of repeated sequences and self-propagating DNA, such as transposons and bacteriophages. In contrast, obligate intracellular bacteria have small genomes with a low content of repeated sequences and no or few genetic parasites. In extreme cases, such as in the 650 kb-genomes of aphid endosymbionts of the genus Buchnera all repeated sequences above 200bp have been eliminated. We speculate that the initial downsizing of the genomes of obligate symbionts and parasites occurred by homologous recombination at repeated genes, leading to the loss of large blocks of DNA as well as to the consumption of repeated sequences. Further sequence elimination in these small genomes seems primarily to result from the accumulation of short deletions within genic sequences. This process may lead to temporary increases in the genomic content of pseudogenes and 'junk' DNA. We discuss causes and long-term consequences of extreme genome size reductions in obligate intracellular bacteria.
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| 43. |
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| 44. |
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| 45. |
- Jouybari, Arash, et al.
(författare)
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Methods comparison for attitude determination of a lightweight buoy by raw data of IMU
- 2019
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Ingår i: Measurement. - : Elsevier. - 0263-2241 .- 1873-412X. ; 135, s. 348-354
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Tidskriftsartikel (refereegranskat)abstract
- Today, one of the most important issues is the determination of instantaneous sea level and distinguishing the Tsunami by floating buoy in the ocean. Usually, gyroscopes are used to measure the angular velocity of a buoy. On the other hand, considering the advancement of various technologies in the field of precise accelerometers, make it possible to use these kinds of sensors for navigation purpose. In this research, stable and optimal methods for determining the orientation of a moving buoy is presented using a combination of the gyroscope, accelerometers, and magnetic sensors data. In order to prove the effectiveness of the proposed methods, the raw data were collected from accelerometers, gyroscopes, and magnetometers of (Xsens MTI-G-700) mounted on a Buoy in coastal waters of Kish Island, Iran. Then, by using the proposed methods, the Euler angles of the buoy are determined, while the Euler angles are derived from the Xsens sensor we are considered as a reference. Based on the results, RMSD for Madgwick algorithm are 0.57° 0.37° and 0.50° for Mahony algorithm are 0.56° 0.37° and 0.50° and finally for Complementary algorithm is 0.63° 0.26° and 2.38° which these values are for roll, pitch, and yaw angles respectively. Thus Mahony algorithm for determining roll and yaw Euler angles is more accurate than other algorithms; however, this differences is negligible compared to the Madgwick algorithm. The Complementary algorithm is less accurate than the other two algorithms, especially for determining the yaw angle of the buoy.
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| 46. |
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| 47. |
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| 48. |
- Leal-Ferreira, M. L., et al.
(författare)
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Magnetic fields around evolved stars: further observations of H2O maser polarization
- 2013
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 554
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Tidskriftsartikel (refereegranskat)abstract
- Context: A low-or intermediate-mass star is believed to maintain a spherical shape throughout the evolution from the main sequence to the asymptotic giant branch (AGB) phase. However, many post-AGB objects and planetary nebulae exhibit non-spherical symmetry. Several candidates have been suggested as factors that can play a role in this change of morphology, but the problem is still not well understood. Magnetic fields are one of these possible agents. Aims. We aim to detect the magnetic field and infer its properties around four AGB stars using H2O maser observations. The sample we observed consists of the following sources: the semi-regular variable RT Vir, and the Mira variables AP Lyn, IK Tau, and IRC+60370. Methods. We observed the 6(1,6)-5(2,3) H2O maser rotational transition in full-polarization mode to determine its linear and circular polarization. Based on the Zeeman effect, one can infer the properties of the magnetic field from the maser polarization analysis. Results. We detected a total of 238 maser features in three of the four observed sources. No masers were found toward AP Lyn. The observed masers are all located between 2.4 and 53.0 AU from the stars. Linear and circular polarization was found in 18 and 11 maser features, respectively. Conclusions. We more than doubled the number of AGB stars in which a magnetic field has been detected from H2O maser polarization. Our results confirm the presence of fields around IK Tau, RT Vir, and IRC+60370. The strength of the field along the line of sight is found to be between 47 and 331 mG in the H2O maser region. Extrapolating this result to the surface of the stars, assuming a toroidal field (proportional to r(-1)), we find magnetic fields of 0.3-6.9 G on the stellar surfaces. If, instead of a toroidal field, we assume a poloidal field (proportional to r(-2)), then the extrapolated magnetic field strength on the stellar surfaces are in the range between 2.2 and similar to 115 G. Finally, if a dipole field (proportional to r(-3)) is assumed, the field strength on the surface of the star is found to be between 15.8 and similar to 1945 G. The magnetic energy of our sources is higher than the thermal and kinetic energy in the H2O maser region of this class of objects. This leads us to conclude that, indeed, magnetic fields probably play an important role in shaping the outflows of evolved stars.
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| 49. |
- Leal-Ferreira, M. L., et al.
(författare)
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Rotten Egg nebula: the magnetic field of a binary evolved star
- 2012
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 540, s. Article Number: A42-
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Tidskriftsartikel (refereegranskat)abstract
- Context. Most of the planetary nebulae (PNe) observed are not spherical. The loss of spherical symmetry occurs somewhere between the asymptotic giant branch (AGB) phase and the PNe phase. The cause of this change of morphology is not yet well understood, but magnetic fields are one of the possible agents. The origin of the magnetic field remains to be determined, and potentially requires the presence of a massive companion to the AGB star. Therefore, further detections of the magnetic field around evolved stars, and in particular those thought to be part of a binary system, are crucial to improve our understanding of the origin and role of magnetism during the late stages of stellar evolution. One such binary is the pre-PN OH231.8+4.2, around which a magnetic field has previously been detected in the OH maser region of the outer circumstellar envelope. Aims. We aim to detect and infer the properties of the magnetic field of the pre-PN OH231.8+4.2 in the H2O maser region that probes the region close to the central star. This source is a confirmed binary with collimated outflows and an envelope containing several maser species. Methods. In this work we observed the 6(1,6)-5(2,3) H2O maser rotational transition to determine its linear and circular polarization. As a result of Zeeman splitting, the properties of the magnetic field can be derived from maser polarization analysis. The H2O maser emissions of OH231.8+4.2 are located within the inner regions of the source (at a few tens of AU). Results. We detected 30 H2O maser features around OH231.8+4.2. The masers occur in two distinct regions that are moving apart with a velocity on the sky of 2.3 mas/year. Taking into account the inclination angle of the source with the line of sight, this corresponds to an average separation velocity of 21 km s(-1). Based on the velocity gradient of the maser emission, the masers appear to be dragged along the direction of the nebula jet. Linear polarization is present in three of the features, and circular polarization is detected in the two brightest features. The circular polarization results imply a magnetic field strength of vertical bar B-parallel to vertical bar similar to 45 mG. Conclusions. We confirm the presence of a magnetic field around OH231.8+4.2, and report the first measurements of its strength within a few tens of AU of the stellar pair. Assuming a toroidal magnetic field, this imples B similar to 2.5 G on the stellar surface. The morphology of the field is not yet determined, but the high scatter found in the directions of the linear polarization vectors could indicate that the masers occur near the tangent points of a toroidal field.
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| 50. |
- Leal-Ferreira, M.L., et al.
(författare)
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Water Maser Emission Around Low/Intermediate Mass Evolved Stars
- 2012
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Ingår i: Proceedings of the International Astronomical Union. - 1743-9213 .- 1743-9221. ; 8:S287, s. 79 - 80
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We present results of Very Long Baseline Array (VLBA) polarimetric 22 GHz H2O maser observations of a number of low/intermediate mass evolved stars. We observed 3 Miras (Ap Lyn, IK Tau and IRC+60370), 1 semi-regular variable (RT Vir) and 1 pPN (OH231.8+4.2). Circular polarization is detected in the H2O maser region of OH231.8+4.2 and we infer a magnetic field of |B||| = ~45 mG. This implies an extrapolated magnetic field of ~2.5 G on the surface of the central star. The preliminary results on RT Vir and IRC+60370 also indicate the first detection of weak H2O maser linear polarization.
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