| 1. |
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| 2. |
- DAWODY, JAZAER, 1959, et al.
(författare)
-
An integrated system for energy-efficient exhaust aftertreatment for heavy-duty vehicles
- 2015
-
Ingår i: Renewable Energy in the Service of Mankind. - Cham : Springer International Publishing. - 9783319177779 - 9783319177762 ; 1, s. 133-143
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- © Springer International Publishing Switzerland 2015. This chapter presents a unique system approach applied in a joint academic- industrial research programme, E4 Mistra, to attain the goals of high energy efficiency and low emissions in an exhaust aftertreatment system for heavy-duty vehicles. The high energy efficiency is achieved by heat recuperation, onboard hydrogen production for NOx reduction, and by finding new solutions for making the aftertreatment system active at low exhaust temperatures. To reach low particulate emissions, a mechanical filter using a sintered metal powder is developed and coated with catalytic material to improve the soot oxidation efficiency. Low NOx emissions are achieved by an efficient NOx reduction catalyst. The integrated E4 Mistra system comprises four technological advances: thermoelectric (TE) materials for heat recuperation, catalytic reduction of NOx over innovative catalyst substrates using either the onboard diesel or biodiesel, H2 from a high-efficiency fuel reformer, and particulate filtration over a porous metal filter. The TE materials are used in a TE generator (TEG) which converts thermal energy into electricity. The TEG is used to recuperate heat from the exhaust-gas recirculation (EGR) circuit of heavy-duty trucks and is expected to generate ~1 kW electric power from 20 kW heat in the exhaust gas. The TEG is integrated in a plate heat exchanger (HEX) designed particularly for this application. Apart from the knowledge and experiences in TEG and heat exchange technologies, a thorough fluid dynamics and TE analysis are performed in this project to understand the governing processes and optimize the system accordingly. The components of the E4 Mistra system are explained in the chapter in addition to test results, which show the system's capacity for H2 production, NOx conversion, particulate matter filtration and soot oxidation, and finally electric power generation via heat recuperation from the exhaust gas using the developed TEG-HEX system.
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| 3. |
- Andersson, Jan, et al.
(författare)
-
Kartläggning av ägarskiften i företag : Utveckling och dokumentation av dataunderlag
- 2014
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Myndigheten för tillväxtpolitiska utvärderingar och analyser, Tillväxtanalys, har haft i uppdrag av regeringen att genomföra kartläggning och analys av ägarskiften i företag. Uppdraget omfattade även att göra jämförelser mellan generationsskiften och andra typer av ägarskiften som inte är åldersbaserade samt belysa möjligheten att följa upp företagens skifte och dynamik över tid. Tillväxtanalys lämnade i oktober 2013 en delrapportering av uppdraget som avser dels en kartläggning av åldersstrukturen i företagsstocken, dels en fördjupad analys av ägarskiften. Denna rapport är en redovisning av uppdragets sista del som innebär utveckling och dokumentation av dataunderlag för identifiering av ägarförändringar.SCB har på uppdrag av Tillväxtanalys undersökt möjligheten att bättre identifiera ägarskiften genom att integrera och göra en matchningskontroll av kompletterande uppgifter gällande delägare i fåmansaktiebolag som kan hämtas från Skatteverket, SKV, med redan befintlig information om företagsdynamik, vilken finns i Företagens och arbetsställenas dynamik, FAD, och den registerbaserade arbetsmarknadsstatisken, RAMS, på SCB. För att göra detta studeras företagens ägarskiften mellan åren 2010 och 2011. Uppdraget omfattar även att beskriva FAD gällande syfte, metodik och innehåll.Cirka 80 procent av samtliga företag oberoende av bolagsform överlevde mellan åren 2010 och 2011. Resterande företag har på något sätt förändrats. Företag läggs ned och andra startar som en del i strukturomvandlingen. Dessutom ser vi att många företag och arbetsställen byter ägare. Näringslivet visar på en stor dynamik och dynamiken omfattar många olika typer av förändringar.Bearbetningarna visar att det med hjälp av RAMS och SKV:s register går att följa och framställa uppgifter om ägarförändringar på ett bra sätt. Detta gäller både för fåmansaktiebolag, där det går att följa individuellt ägande, och för övriga juridiska former där förändringar i organisationsnummer kan spåras, vilket indikerar ändrade ägarförhållanden. Analysen visar att SKV:s register är ett bra komplement till RAMS och FAD och tillför ytterligare information. Samkörningen av dessa registerdata ger mer information än vad som kan fås ut av respektive registerkällor separat. Det går dessutom att koppla på annan information om anställda, omsättning och olika mått på lönsamhet från andra register.Tillväxtanalys rekommenderar därför att SCB får tillgång till register gällande ägarandelar från Skatteverket under en längre tidsperiod än enbart de undersökta åren. Detta för att kunna sammanställa en databas som möjliggör bättre och mer precisa analyser av olika dimensioner av näringslivsdynamik och ägarförändringar. Det vore dessutom önskvärt att denna databas görs tillgänglig för forskning och studier som ökar kunskapen om olika dimensioner av näringslivets strukturomvandling.
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| 4. |
- DAWODY, JAZAER, 1959, et al.
(författare)
-
E4-Mistra, a research program for the development of an energy efficient low emission exhaust aftertreatment system for heavy duty vehicles
- 2012
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Ingår i: World Renewable Energy Forum, WREF 2012, Including World Renewable Energy Congress XII and Colorado Renewable Energy Society (CRES) Annual Conference. - : American Solar Energy Society. - 9781622760923 ; , s. 4530-4536
-
Konferensbidrag (refereegranskat)abstract
- This paper presents a unique system approach applied in a joint academic - industrial research program, E4 Mistra, to reach the goals of energy efficiency and low emissions exhaust aftertreatment system for heavy duty vehicles. The high energy efficiency is achieved by heat recuperation, on-board hydrogen production for use in both an auxiliary power unit and for NOx reduction and by finding new solutions for making the after-treatment system active at low exhaust temperatures. To reach low particulate emissions a mechanical filter using a sintered metal filter is developed. Low NOx emissions are achieved by an efficient NOx reduction catalyst. The system is based on four technological advances: Thermoelectric material s for heat recuperation, catalytic reduction of NOx over innovative catalyst substrates using hydrocarbons from the fuel and H2 from a high efficiency fuel reformer, and particulate filtration over a porous metal filter.
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| 5. |
- Forslund, Sofia K., et al.
(författare)
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Combinatorial, additive and dose-dependent drug–microbiome associations
- 2021
-
Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 600:7889, s. 500-505
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Tidskriftsartikel (refereegranskat)abstract
- During the transition from a healthy state to cardiometabolic disease, patients become heavily medicated, which leads to an increasingly aberrant gut microbiome and serum metabolome, and complicates biomarker discovery1–5. Here, through integrated multi-omics analyses of 2,173 European residents from the MetaCardis cohort, we show that the explanatory power of drugs for the variability in both host and gut microbiome features exceeds that of disease. We quantify inferred effects of single medications, their combinations as well as additive effects, and show that the latter shift the metabolome and microbiome towards a healthier state, exemplified in synergistic reduction in serum atherogenic lipoproteins by statins combined with aspirin, or enrichment of intestinal Roseburia by diuretic agents combined with beta-blockers. Several antibiotics exhibit a quantitative relationship between the number of courses prescribed and progression towards a microbiome state that is associated with the severity of cardiometabolic disease. We also report a relationship between cardiometabolic drug dosage, improvement in clinical markers and microbiome composition, supporting direct drug effects. Taken together, our computational framework and resulting resources enable the disentanglement of the effects of drugs and disease on host and microbiome features in multimedicated individuals. Furthermore, the robust signatures identified using our framework provide new hypotheses for drug–host–microbiome interactions in cardiometabolic disease.
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| 6. |
- Stenberg, Rebecca, 1957-, et al.
(författare)
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Lokalisering i oländig terräng : Slutrapport Terrängpejlen-projektet
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Flygplan och personer som råkar i nöd i oländig terräng kan använda nödsändare som via satellitsystemet COSPAS-SARSAT kan meddela en räddningscentral att det är ett nödläge, samt ungefärlig position. För att sedan lokalisera nödsändaren används ofta flygande resurser, till exempel helikopter, med fast pejl-utrustning som kan fastställa riktningen mot signalkällan. Ibland kan dock flygande resurser inte användas, som till exempel vid dåligt väder eller om de är upptagna på annat uppdrag, och i dagsläget finns inget bra markbaserat alternativ. Syftet med projektet Terrängpejlen var därför att utveckla och utvärdera ett system för markbaserade pejlresurser, så kallad handpejl. Följande slutsatser kunde dras från projektet:Handpejl kommer att behövas mycket sällan vid skarpa insatser. En analys av de senaste fem årens relevanta incidenter tyder på att handpejl inte hade varit till nytta vid något tillfälle. Detta kan dock komma att ändras till exempel. som en följd av ökad frekvens av extremväder, eller vid höjd beredskap på grund av militära hot.Det finns i dag ingen pejl som är perfekt för ändamålet att lokalisera nödsändare. Av de tre pejlar som testades i projektet bedömdes två kunna uppfylla grundfunktionen, att hitta en nödsändare, men hade brister i till exempel användarvänlighet. Bäst för ändamålet bedömdes Rhotheta RT 400 vara, medan Rohde & Schwarz PR 200 är att föredra om pejlen också ska användas för att hitta störsändare, vilket kan vara önskvärt om den är stationerad på en flygplats.Pejling kan utföras av räddningstjänstpersonal på utvalda flygplatser i samverkan med fjällräddare som får agera transportörer. Vid flera flygplatser finns det fortfarande kvar pejlutrustning, trots slopat krav på detta, och det finns också intresse av att upprätthålla kunskapen.Utlarmning och kommunikation bör ske enligt dagens rutin med regelbundna samverkanskonferenser. Direkta kontaktvägar mellan pejloperatörer (flygplatspersonal) och transportörer (fjällräddare) måste upprättas och samverkan måste övas regelbundet.Nödvändig utbildning och övning omfattar utbildning av lokala instruktörer, lokal operatörsutbildning samt regelbundna samverkansövningar. Instruktörsutbildning kan genomföras av Sjöfartsverket. Instruktörerna sköter sedan lokala utbildningar och övningar, vilka bör genomföras minst en gång per år. Dessa kan kombineras med återkommande samverkansövningar tillsammans med Sjö- och flygräddningscentralen, Polisen, SOS Alarm och Fjällräddningen.Sjöfartsverket bör vara ansvarig organisation som äger pejlarna och lånar ut dessa till flygplatserna, samt har ansvar för tillsyn av verksamheten. Urval av flygplatser bör göras i första hand med utgångspunkt från geografiskt täckningsområde. Utslaget på årsbasis blir den dominerande kostnaden vid en implementering att ha flygplatspersonal i beredskap. Med ett riktpris på 250 000 SEK per pejl, blir det också en viss investeringskostnad om många flygplatser ska utrustas.
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| 7. |
- Ahnlund, Petra, 1973-, et al.
(författare)
-
Prevalence and correlates of sexual, physical, and psychological violence against women and men of 60 to 74 years in Sweden
- 2020
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Ingår i: Journal of Interpersonal Violence. - Thousand Oaks : Sage Publications. - 0886-2605 .- 1552-6518. ; 35:5-6, s. 1539-1561
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Tidskriftsartikel (refereegranskat)abstract
- Past-year sexual, physical, and psychological violence against women and men aged 60 to 74 years was studied. The data derived from a nationally representative survey on violence in which approximately 2,800 women and men aged 60 to 74 years in Sweden participated. Women were significantly more likely to have been subjected to at least one form of violence in the past year. The prevalence of sexual violence as well as systematic and repeated psychological violence was found to be significantly higher for women than for men. Sexual violence was the most common form of violence against women. Systematic and repeated psychological violence was the most common form of violence against men. Additional gender differences were found in relation to victim characteristics. While associations among women were found between violence victimization and sociodemographic characteristics, health as well as social capital, only health-related characteristics were found to be associated with past-year violence victimization among men. Among women, economic problems, posttraumatic stress disorder (PTSD) symptoms, lack of trust in other people, and not having anyone to talk to were associated with violence victimization. Poor psychological health and an at-risk consumption of alcohol were found to be associated with violence victimization among men. The results highlight the importance of research on violence victimization to assess gender differences also when inquiring into the situation among persons in older generations. The results also indicate practical implications for caring professions; the need to inquire into the experiences of violence among older persons and to pay particular attention to these characteristics when encountering women and men in this age interval.
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| 8. |
- Anderson, Johan, 1973, et al.
(författare)
-
Fire Spread due to Thermal Runaway in a Lithium-ion Battery Cell
- 2014
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Ingår i: Fires in vehicles (FIVE) 2014 Conference proceedings. ; 2014, s. 267-270
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The risk of spreading of fire between Lithium-ion battery cells is assessed using Finite-Element (FE) modelling of the heat transfer initiated by a thermal runaway. The results are contrasted to experimental data where the heat release rate (HRR) is utilized as an input to the simulation. It is found that the temperature increase in a neighbouring cell can be quantitatively estimated during theearly stages of the fire taking into account the anisotropic thermal conductivity of the cells.
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| 9. |
- Anderson, Johan, 1973, et al.
(författare)
-
Thermal modeling of fire propagation in lithium-ion batteries
- 2015
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Ingår i: The 24th International Technical Conference on the Enhanced Safety of Vehicles (ESV). Gothenburg, Sweden on June 8-11, 2015.
-
Konferensbidrag (refereegranskat)abstract
- The objective of the present work is to assess the risk of spreading of fire between Lithium-ion battery cellsinitiated by a thermal runaway. In particular it aims at developing means to predict the temperature of cells inthe vicinity of an overheated cell during the first 5-7 minutes after the thermal event in a Li-ion cell that has anorganic based electrolyte which is flammable. Finite-Element (FE) modelling is used to compute the heattransfer between cells. The spreading model is assessed modeling a scenario where the cells are exposed to a15 kW propane burner. Two different models where utilized, one that considers the conjugate heat transferbetween the surrounding hot gases and the battery cells while the second is a thermal model where theboundary conditions are measured in a mock-up test. The results from the two models are contrasted toexperimental data where the heat release rate (HRR) is utilized as an input to the simulation. It is found thatthe temperature increase in a neighboring cell can be quantitatively estimated in certain cases during the earlystages of the fire taking into account the anisotropic thermal conductivity of the cells using the conjugate heattransfer model. Moreover, the thermal model captures the qualitative behavior of the test results, however, thetemperature increase is slower in the computational model.
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| 10. |
- Andersson, Annika, et al.
(författare)
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Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease
- 2019
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Ingår i: Clinica Chimica Acta. - : Elsevier B.V.. - 0009-8981 .- 1873-3492. ; 494, s. 79-93
-
Tidskriftsartikel (refereegranskat)abstract
- Detailed knowledge of protein changes in cerebrospinal fluid (CSF) across healthy and diseased individuals would provide a better understanding of the onset and progression of neurodegenerative disorders. In this study, we selected 20 brain-enriched proteins previously identified in CSF by antibody suspension bead arrays (SBA) to be potentially biomarkers for Alzheimer's disease (AD) and verified these using an orthogonal approach. We examined the same set of 94 CSF samples from patients affected by AD (including preclinical and prodromal), mild cognitive impairment (MCI), non-AD dementia and healthy individuals, which had previously been analyzed by SBA. Twenty-eight parallel reaction monitoring (PRM) assays were developed and 13 of them could be validated for protein quantification. Antibody profiles were verified by PRM. For seven proteins, the antibody profiles were highly correlated with the PRM results (r > 0.7) and GAP43, VCAM1 and PSAP were identified as potential markers of preclinical AD. In conclusion, we demonstrate the usefulness of targeted mass spectrometry as a tool for the orthogonal verification of antibody profiling data, suggesting that these complementary methods can be successfully applied for comprehensive exploration of CSF protein levels in neurodegenerative disorders.
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| 11. |
- Andersson, A. F., et al.
(författare)
-
Comparative analysis of human gut microbiota by barcoded pyrosequencing
- 2008
-
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 3:7
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Tidskriftsartikel (refereegranskat)abstract
- Humans host complex microbial communities believed to contribute to health maintenance and, when in imbalance, to the development of diseases. Determining the microbial composition in patients and healthy controls may thus provide novel therapeutic targets. For this purpose, high-throughput, cost-effective methods for microbiota characterization are needed. We have employed 454-pyrosequencing of a hyper-variable region of the 16S rRNA gene in combination with sample-specific barcode sequences which enables parallel in-depth analysis of hundreds of samples with limited sample processing. In silico modeling demonstrated that the method correctly describes microbial communities down to phylotypes below the genus level. Here we applied the technique to analyze microbial communities in throat, stomach and fecal samples. Our results demonstrate the applicability of barcoded pyrosequencing as a high-throughput method for comparative microbial ecology.
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| 12. |
- Andersson, Emmelie, et al.
(författare)
-
När myren blir som fnöske : En utvärdering av Fortifikationsverkets hantering av skogsbränderna 2018
- 2019
-
Rapport (populärvet., debatt m.m.)abstract
- Under sommaren 2018 utbröt ett stort antal skogsbränder runt om i Sverige på grund av det ihållande varma och torra vädret. Bränder uppstod även på flera av Fortifikationsverkets fastigheter. Den största brandutvecklingen skedde på Älvdalens skjutfält i Dalarna och krävde en gemensam insats från kommunala räddningstjänsten, Fortifikationsverkets egen personal, Försvarsmakten, Hemvärnet och frivilliga för att hantera. Som fastighetsägare ansvarade Fortifikationsverket främst för eftersläcknings- och bevakningsarbete. Fortifikationsverkets hantering av bränderna innehöll många positiva delar: initiativförmåga, improvisation och engagemang. Människor ville och kunde göra en insats. Alla dessa är viktiga komponenter i krishantering. Då detta är en av de största händelserna som Fortifikationsverket har fått hantera så har det lett till en rad nya kunskaper och erfarenheter som kan bidra till att utveckla myndighetens krisberedskap, men också till totalförsvarsplaneringen.Fortifikationsverket gav Försvarshögskolans Centrum för totalförsvar och samhällets säkerhet (FHS/CTSS) i uppdrag att dels utvärdera myndighetens insats i hanteringen av skogsbränderna vid Älvdalens skjutfält, och dels myndighetens generella förmåga att hantera uppkomna kriser. Underlaget till utvärderingen består dels av en analys av de dokument som togs fram under insatsen, av myndighetens instruktioner och planer samt av gällande författningar. Därtill har intervjuer genomförts med medarbetare och chefer inom Fortifikationsverket som satt på viktiga krisledningsfunktioner vid insatsen, samt med räddningstjänsten som samverkade med Fortifikationsverket under bränderna. Utvärderingen har resulterat i ett antal slutsatser och rekommendationer som presenteras kortfattat nedan. Rapporten har även kompletterats med en bilaga, ”Typfall skogsbrand”. Bilagan består av ett scenario där utbredda skogsbränder drabbar Fortifikationsverkets fastigheter och olika situationer uppstår som måste hanteras av myndigheten. Därutöver finns en checklista som kan fungera som stöd både före, under och efter en händelse, till exempel en skogsbrand. Bilagan är tänkt att användas till utbildning, övning och planering.
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| 13. |
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| 14. |
- Andersson, Fredrik, 1973-, et al.
(författare)
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Between Private Interests and the State : Corporatist Strategies in the Swedish Railway Council, 1902–67
- 2015
-
Ingår i: Journal of Transport History. - : Sage Publications. - 0022-5266 .- 1759-3999. ; 36:2, s. 151-169
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Tidskriftsartikel (refereegranskat)abstract
- This study explores the strategies employed by the Swedish RailwayCouncil to influence national railway policy from 1902 to 1967. The Council was a corporatist arrangement and functioned as a broker betweenindustrial and regional interests and the public railways. The resultsshow that though the Council's policy influence in many cases wasmarginal, there were occasions when the members could use the Council asa tool to influence railway policy, most notably the division of thenetwork into profitable and unprofitable lines, with different forms ofgovernment subsidies. The Council's influence gained from a shift inarguments from that tariffs should be high enough to deliver a return onthe invested capital, to an emphasis on having tariffs that could supportnational and regional economic development, even if it created commerciallosses. When Swedish transport policy shifted in the 1960s, the Railway Council gradually lost its importance and eventually dissolved.
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| 15. |
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| 16. |
- Andersson, Fredrik, 1973-, et al.
(författare)
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Bland småbrukare och storspioner
- 2008
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Ingår i: Provins: Norrländsk litterär tidskrift. - Piteå : Norrländska författarsällskapet. - 0280-9974. ; :1
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 17. |
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| 18. |
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| 19. |
- Andersson, Fredrik, 1974-, et al.
(författare)
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Female top management in family firms and non-family firms : Evidence from total population data
- 2018
-
Ingår i: International Journal of Entrepreneurship and Small Business. - : InderScience Publishers. - 1476-1297 .- 1741-8054. ; 35:3, s. 303-326
-
Tidskriftsartikel (refereegranskat)abstract
- We exploit information on ownership, management and kinship to study the representation of women in top management teams in Swedish family and non-family firms among domiciled limited liability firms over the years 2004 to 2010. The share of female top managers is analysed across listed and non-listed firms as well as across industries. We then estimate the likelihood that a woman is elected into the top management team in family and non-family firms using a probit regression model where we control for firm- A nd individual-level characteristics, including the gender distribution of the firm and kinship relations to existing board members and firm owners. We find that non-listed family firms are more likely to appoint female top managers, whereas we find no differences among listed firms. Moreover, we find that the gender composition and kinship structures of firms influence the appointment of female top managers.
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| 20. |
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| 21. |
- Andersson, Fredrik, 1973-, et al.
(författare)
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Kamrat med rätt att kugga
- 2001
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Ingår i: Lärares liv - vision och verklighet. - Umeå : Universitetspedagogiskt centrum.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 22. |
- Andersson, Fredrik, 1973-
(författare)
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Mot framtiden på gamla spår? : Regionala intressegrupper och beslutsprocesser kring kustjärnvägarna i Norrland under 1900-talet
- 2004
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In this dissertation the construction of two coastal railways, the East Coast Line and the Bothnia Line, in the Norrland region of northern Sweden is used as a case study of how regionally based interest groups are formed, and how they gain access to decision-making processes on a national level. In periods when a number of preconditions were in place, a window of opportunity opened for the coastal railway that the regional elites could exploit. Among these was the ability to form a coherent regional interest group, through institutions that created platforms and power-bases that enable regional elites to co-operate and act on regional and national levels.The existence of an institutional framework that was adapitve towards regional railway promotion was also important. The study shows that the coastal railway had a very flexible role on the agenda, as it provided a fixed solution against which actors could pin a multitude of different problems. An important factor for explaining the development of the coastal railway question in Norrland was the ideological notion of the region itself. Being a vast, resource-rich and sparsely populated region, Norrland had almost always received special consideration in both public opinion and national policy making. It also created a remarkable stubbornness among the regional actors in working for the coastal railway. Regional interest groups had also learnt that linking their claims to Norrland's peripheral position had high legitimacy on the national arena, by claiming the need for regional fairness and/or the national importance of the regional export-intensive industries. This was instrumental in justifying the repeated exemptions from the national railway policy regimes that ultimately were decissive in making the regional elites successful.
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| 23. |
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| 24. |
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| 25. |
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| 26. |
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| 27. |
- Andersson, Fredrik, 1974-, et al.
(författare)
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The Characteristics and Performance of Family Firms : Exploiting information on ownership, governance and kinship using total population data
- 2017
-
Rapport (refereegranskat)abstract
- Family firms are often considered characteristically different from non-family firms, and the economic implications of these differences have generated significant academic debate. However, our understanding of family firms suffers from an inability to identify them in total population data, as this requires information on owners, their kinship and involvement in firm governance, which is rarely available. We present a method for identifying domiciled family firms using register data that offers greater accuracy than previous methods. We then apply it to data from Statistics Sweden concerning firm ownership, governance and kinship over the years 2004-2010. Next, we use Swedish data to estimate these firms’ economic contribution to total employment and gross domestic product (GDP) and compare them to private domiciled non-family firms in terms of their characteristics and economic performance. We find that the family firm is the prevalent organizational form, contributing to over one-third of all employment and GDP. Family firms are common across industries and sizes, ranging from the smallest producers to the largest multinational firms. However, their characteristics differ across sizes and legal forms, thereby indicating that the seemingly contradictory findings among previous studies on family firms may be due to unobserved heterogeneity. We furthermore find that they are smaller than private non-family firms in employment and sales and carry higher solidity, although they are more profitable. These differences diminish with firm size, however. We conclude that the term ‘family firm’ contains great diversity and call for increased attention to their heterogeneity.
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| 28. |
- Andersson, Fredrik, 1974-, et al.
(författare)
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The Characteristics of Family Firms : Exploiting Information on Ownership, Kinship and Governance Using Total Population Data
- 2018
-
Ingår i: Small Business Economics. - : Kluwer Academic/Plenum Publishers. - 0921-898X .- 1573-0913. ; 51:3, s. 539-556
-
Tidskriftsartikel (refereegranskat)abstract
- Family firms are often considered characteristically different from non-family firms. However, our understanding of family firms suffers from an inability to identify them in total population data; information is rarely available regarding owners, their kinship, and their involvement in firm governance. We present a method for identifying domiciled family firms using register data; this method offers greater accuracy than previous methods. We apply this method to Swedish data concerning firm ownership, governance, and kinship from 2004 to 2010. We find that the family firm is a significant organizational form, contributing over one third of all employment and gross domestic product (GDP). Family firms are common in most industries and range in size. Furthermore, we find that, compared to private non-family firms, family firms have fewer total assets, employment, and sales and carry higher solidity, although family firms are more profitable. These differences diminish with firm size. We conclude that the term “family firm” includes a large variety of firms, and we call for increased attention to their heterogeneity.
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| 29. |
- Andersson, Fredrik, 1973-, et al.
(författare)
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The vision thing : Actors, decision-making and lock-in effects in Swedish road safety policy since the 1990s
- 2008
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This paper investigates the introduction of and consequences of the “Vision Zero” (Nollvisionen) that was part of a law passed in 1997 and called for a radical reduction of deaths caused by road traffic. We try to answer the question why the Vision Zero has failed to reach its goals for the last ten years. The introduction of the Vision Zero can be explained with a combination of changes in traffic policy and welfare policy, together with a reorganization of the transport sector that created new opportunities for old interest groups. Our main conclusion is that the strong idealistic and visionary political goals in the Vision Zero are in line with a Swedish tradition of over-arching visionary national goals for the transport sector in general. Idealistic goals suppressed critical objections, but at the same time there were insufficient resources for investments and lack of approval for the policy from actors within the sector, which can create lock-in effects and actually prevent effective policies from being implemented. This might explain the relative ineffectiveness of the policy, and the slim chances of the Vision Zero to ever being achieved.
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| 30. |
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| 31. |
- Andersson, Henrik, et al.
(författare)
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Assaying cardiac biomarkers for toxicity testing using biosensing and cardiomyocytes derived from human embryonic stem cells
- 2010
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Ingår i: JOURNAL OF BIOTECHNOLOGY. - : Elsevier Science B.V., Amsterdam.. - 0168-1656 .- 1873-4863. ; 150:1, s. 175-181
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Tidskriftsartikel (refereegranskat)abstract
- Human embryonic stem cell (hESC) derived cardiomyocytes are in the present study being used for testing drug-induced cardiotoxicity in a biosensor set-up. The design of an in vitro testing alternative provides a novel opportunity to surpass previous methods based on rodent cells or cell lines due to its significantly higher toxicological relevance. In this report we demonstrate how hESC-derived cardiomyocytes release detectable levels of two clinically decisive cardiac biomarkers, cardiac troponin T and fatty acid binding protein 3, when the cardiac cells are exposed to the well-known cardioactive drug compound. doxorubicin. The release is monitored by the immuno-biosensor technique surface plasmon resonance, particularly appropriate due to its capacity for parallel and high-throughput analysis in complex media.
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| 32. |
- Andersson, Heléne, 1973, et al.
(författare)
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Trauma-induced reactive gliosis is reduced after treatment with octanol and carbenoxolone
- 2011
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Ingår i: Neurological research. - 0161-6412. ; 33:6, s. 614-624
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Tidskriftsartikel (refereegranskat)abstract
- Background: Reactive gliosis and scar formation after brain injury can inhibit the recovery process. As many glial cells utilize gap junctions for intercellular signaling, this study investigated whether two commonly used gap junction blockers, octanol and carbenoxolone, could attenuate reactive gliosis following a minor traumatic brain injury. Methods: Octanol (710 mg/kg) or carbenoxolone (90 mg/kg) was administered 30 minutes before or after a needle track injury in adult male Sprague-Dawley rats. To mark dividing cells, animals were injected with bromodeoxyuridine (BrdU; 150 mg/kg) intraperitoneally two times per day, 8 hours apart and killed 2 days later. Immunohistochemistry for BrdU and markers for reactive glial cells [glial fibrillary acidic protein (GFAP), ED1, and NG2] were investigated using immunohistochemistry and western blot techniques. Results: Two days after injury, increased cellular proliferation, activated astrocytes and microglia, and upregulation of NG2 expression were observed surrounding the injury site. Octanol and carbenoxolone administrated prior to injury significantly decreased cell proliferation by 60 and 70% respectively. The distance of GFAP immunoreactive astrocytes from the wound margin was decreased by 32 and 18% when octanol was administrated prior to or post injury respectively. Treatment with octanol also decreased the number of reactive microglia by 55% and, when administrated prior to injury, octanol reduced the distance of NG2 expression from the wound by 48%. Conclusion: The present study demonstrates that two important components of reactive gliosis, cellular activation and proliferation, can be attenuated by octanol and carbenoxolone.
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| 33. |
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| 34. |
- Andersson, Petra, et al.
(författare)
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Modelling of thermal events in Lithium-ion batteries
- 2015
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Ingår i: ESFSS 2015 2nd European Symposium on Fire Safety Science. 16 - 18 June 2015 European University Cyprus, Cyprus..
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Konferensbidrag (refereegranskat)abstract
- Lithium-ion batteries are seen as part of the solution to meet the environmental concerns for many areas including the automotive sector. The Li-ion technology has many good properties such as a high energy-density but also drawbacks such as its narrow window of stable operation. If the cell is e.g. heated up it might go into a thermal runaway in which the cell rapidly heats itself up, a process that might spread also to adjacent cells. In order to investigate whether a thermal event will progress to adjacent cells, it is important to be able to model the heat transport within a battery module properly. A first attempt to model the spreading has been made using Comsol Multiphysics for a test case where one cell is exposed to a heating source and then the heating spreads to other cells.
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| 35. |
- Andersson, Patrik U, 1970, et al.
(författare)
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Formation of Highly Rovibrationally Excited Ammonia from Dissociative Recombination of NH4
- 2010
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Ingår i: Journal of Physical Chemistry Letters. - : American Chemical Society (ACS). - 1948-7185. ; 1:17, s. 2519-2523
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Tidskriftsartikel (refereegranskat)abstract
- The internal energy distribution of ammonia formed in the dissociative recombination (DR) of NH4+ with electrons has been studied by an imaging technique at the ion storage ring CRYRING. The DR process resulted in the formation of NH3 + H (0.90 ± 0.01), with minor contributions from channels producing NH2 + H2 (0.05 ± 0.01) and NH2 + 2H (0.04 ± 0.02). The formed NH3 molecules were highly internally excited, with a mean rovibrational energy of 3.3 ± 0.4 eV, which corresponds to 70% of the energy released in the neutralization process. The internal energy distribution was semiquantitatively reproduced by ab initio direct dynamics simulations, and the calculations suggested that the NH3 molecules are highly vibrationally excited while rotational excitation is limited. The high internal excitation and the translational energy of NH3 and H will influence their subsequent reactivity, an aspect that should be taken into account when developing detailed models of the interstellar medium and ammonia-containing plasmas.
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| 36. |
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| 37. |
- Andersson-Sköld, Yvonne, et al.
(författare)
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An integrated method for assessing climate-related risks and adaptation alternatives in urban areas
- 2015
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Ingår i: Climate Risk Management. - : Elsevier BV. - 2212-0963. ; 7, s. 31-50
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Tidskriftsartikel (refereegranskat)abstract
- © 2015 The Authors. The urban environment is a complex structure with interlinked social, ecological and technical structures. Global warming is expected to have a broad variety of impacts, which will add to the complexity. Climate changes will force adaptation, to reduce climate-related risks. Adaptation measures can address one aspect at the time, or aim for a holistic approach to avoid maladaptation. This paper presents a systematic, integrated approach for assessing alternatives for reducing the risks of heat waves, flooding and air pollution in urban settings, with the aim of reducing the risk of maladaptation. The study includes strategies covering different spatial scales, and both the current climate situation and the climate predicted under climate change scenarios. The adaptation strategies investigated included increasing vegetation; selecting density, height and colour of buildings; and retreat or resist (defend) against sea-level rise. Their effectiveness was assessed with regard to not only flooding, heat stress and air quality but also with regard to resource use, emissions to air (incl. GHG), soil and water, and people's perceptions and vulnerability. The effectiveness of the strategies were ranked on a common scale (from -3 to 3) in an integrated assessment. Integrated assessments are recommended, as they help identify the most sustainable solutions, but to reduce the risk of maladaptation they require experts from a variety of disciplines. The most generally applicable recommendation, derived from the integrated assessment here, taking into account both expertise from different municipal departments, literature surveys, life cycle assessments and publics perceptions, is to increase the urban greenery, as it contributes to several positive aspects such as heat stress mitigation, air quality improvement, effective storm-water and flood-risk management, and it has several positive social impacts. The most favourable alternative was compact, mid-rise, light coloured building design with large parks/green areas and trees near buildings.
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| 38. |
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| 39. |
- Andree, Maria, et al.
(författare)
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Knowledge Products from Close-To-Practice Research
- 2024
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Ingår i: Round table presentation at the NERA-conference, 6-8 March, Malmö University.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- ‘Close-to-practice research’ has received increased attention across the Nordic countries. Following the British Education Research Association (BERA), the notion of ‘close-to-practice research’ is used to refer to educational research that is based on problems in practice, often involves researchers working in partnership with practitioners in schools and addresses issues of relevance to practitioners. This roundtable focuses on how close-to-practice research can contribute to the knowledge base of the teaching profession by bringing together perspectives from didactics, school improvement and educational policy. More specifically, the interest is directed toward what characterizes the knowledge produced through practice-based research that may have significance for teachers' professional knowledge base and practice. The roundtable conversation builds on a previous analysis of what kinds of knowledge products are generated in didactic close-to-practice research where teachers and researchers work together within the research environment Stockholm Teaching & Learning Studies. As a result of this analysis a typology of knowledge products was proposed including: (i) descriptions of knowing, (ii) teaching design, (iii) didactic examples and (iv) methodological tools. It has been proposed that additional knowledge products may be developed, such as artifacts to be used in teaching (e.g. lesson plans, visual representations). The roundtable will include the following points of discussion: 1) a brief presentation of the typology, 2) challenging and developing the typology of knowledge products proposed by previous research by investigating different cases of close-to-practice research from traditions of action research and practice-developing research within subject-didactics, and 3) discussing how the notion of knowledge products may contribute to advancing the conversation on cumulativity in the field of educational research in general, and in relation to syntheses of close-to-practice research in particular. The participants will be engaged in conversations on the desirability and feasibility of striving towards cumulativity.
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| 40. |
- Andrikopoulos, Petros, et al.
(författare)
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Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide
- 2023
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Ingår i: Nature Communications. - 2041-1723 .- 2041-1723. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- The host-microbiota co-metabolite trimethylamine N-oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear. We applied "explainable" machine learning, univariate, multivariate and mediation analyses of fasting plasma TMAO concentration and a multitude of phenotypes in 1,741 adult Europeans of the MetaCardis study. Here we show that next to age, kidney function is the primary variable predicting circulating TMAO, with microbiota composition and diet playing minor, albeit significant, roles. Mediation analysis suggests a causal relationship between TMAO and kidney function that we corroborate in preclinical models where TMAO exposure increases kidney scarring. Consistent with our findings, patients receiving glucose-lowering drugs with reno-protective properties have significantly lower circulating TMAO when compared to propensity-score matched control individuals. Our analyses uncover a bidirectional relationship between kidney function and TMAO that can potentially be modified by reno-protective anti-diabetic drugs and suggest a clinically actionable intervention for decreasing TMAO-associated excess cardiovascular risk.
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| 41. |
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| 42. |
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| 43. |
- Carlsson, Per-Ola, et al.
(författare)
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Chronically decreased oxygen tension in rat pancreatic islets transplantedunder the kidney capsule
- 2000
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Ingår i: Transplantation. - 0041-1337 .- 1534-6080. ; 69:5, s. 761-766
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: A factor of potential importance in the failure of islet grafts is poor or inadequate engraftment of the islets in the implantation organ. This study measured the oxygen tension and blood perfusion in 1-, 2-, and 9-month-old islet grafts. METHODS: The partial pressure of oxygen was measured in pancreatic islets transplanted beneath the renal capsule of diabetic and nondiabetic recipient rats with a modified Clark electrode (outer tip diameter 2-6 microm). The size of the graft (250 islets) was by purpose not large enough to cure the diabetic recipients. The oxygen tension in islets within the pancreas was also recorded. Blood perfusion was measured with the laser-Doppler technique. RESULTS: Within native pancreatic islets, the partial pressure of oxygen was approximately 40 mm Hg (n=8). In islets transplanted to nondiabetic animals, the oxygen tension was approximately 6-7 mm Hg 1, 2, and 9 months posttransplantation. No differences could be seen between the different time points after transplantation. In the diabetic recipients, an even more pronounced decrease in graft tissue oxygen tension was recorded. The mean oxygen tension in the superficial renal cortex surrounding the implanted islets was similar in all groups (approximately 15 mm Hg). Intravenous administration of glucose (0.1 gxkg(-1)x min(-1)) did not affect the oxygen tension in any of the investigated tissues. The islet graft blood flow was similar in all groups, measuring approximately 50% of the blood flow in the kidney cortex. CONCLUSION: The oxygen tension in islets implanted beneath the kidney capsule is markedly lower than in native islets up to 9 months after transplantation. Moreover, persistent hyperglycemia in the recipient causes an even further decrease in graft oxygen tension, despite similar blood perfusion. To what extent this may contribute to islet graft failure remains to be determined.
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| 44. |
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| 45. |
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| 46. |
- Eklund Karlsson, Leena, et al.
(författare)
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The meaning of health, well-being, and quality of life perceived by Roma people in West Sweden
- 2013
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Ingår i: Societies. - : MDPI AG. - 2075-4698. ; 3:2, s. 243-260
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Tidskriftsartikel (refereegranskat)abstract
- Many Roma people in Sweden are on the margins of society and face problems of social exclusion, institutional discrimination, low education, unemployment, and poor health. The aim is to describe how a group of Roma people, in West Sweden, understand health, well-being, and quality of life within the Roma context, and how they cope with their life-situation. Data consisted of qualitative interviews. The data were analyzed qualitatively using a phenomenological hermeneutic approach. The respondents mainly understood the concept of Health as "being healthy" and "feeling good". Elements that were crucial part of the respondents' health perception were being employed, having an education, social support from family and friends, freedom and security, and the extent of involvement in society. The results indicate that the respondents perceive their health and life situation as good, despite of their marginalized situation and discrimination.
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| 47. |
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| 48. |
- Franke Stenport, Victoria, 1970, et al.
(författare)
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Precipitation of calcium phosphate in the presence of albumin on titanium implants with four different possibly bioactive surface preparations. An in vitro study
- 2008
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Ingår i: Journal of Materials Science: Materials in Medicine. - : Springer Science and Business Media LLC. - 0957-4530 .- 1573-4838. ; 19:12, s. 3497-3505
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the present study was to compare the nucleating behaviour on four types of bioactive surfaces by using the simulated body fluid (SBF) model with the presence albumin. Titanium discs were blasted (B) and then prepared by alkali and heat treatment (AH), anodic oxidation (AO), fluoridation (F), or hydroxyapatite coating (HA). The discs were immersed in SBF with 4.5 mg/ml albumin for 3 days, 1, 2, 3 and 4 weeks and analysed with scanning electron microscopy/energy dispersive X-ray analysis (SEM/EDX) and X-ray photoelectron spectroscopy (XPS). Topographic surface characterisation was performed with a contact stylus profilometer. The results demonstrated that the bioactive surfaces initiated an enhanced calcium phosphate (CaP) formation and a more rapid increase of protein content was present on the bioactive surfaces compared to the blasted control surface. The observation was present on all bioactive surfaces. The fact that there was a difference between the bioactive surfaces and the blasted control surface with respect to precipitation of CaP and protein content on the surfaces support the fact that there may be biochemical advantages in vivo by using a bioactive surface.
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| 49. |
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| 50. |
- Frihammar, Mattias, PhD, 1967-, et al.
(författare)
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I kalla krigets spår : hot, våld och beskydd som kulturarv
- 2023
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Bok (refereegranskat)abstract
- Det förflutna används ständigt för att ge mening åt nuet. I kalla krigets spår skildrar framväxten av ett nytt svenskt militärt kulturarv. Här visas hur minnen och lämningar från en tid fylld av rädsla och säkerhetspolitiska spänningar får nya innebörder när bunkrar och nedlagda militäranläggningar omvandlas till museer, lyxbostäder och spännande besöksmål.Genom fältbesök vid en rad militära kulturarvsplatser runt om i Sverige har författarna undersökt vilka miljöer, föremål och känslor som idag får representera kalla kriget. De visar hur dåtidens hemligheter, hotbilder och militärfordon både blir kittlande och fascinerande inslag i kulturarvet och förmedlar idéer om trygghet och beskydd.Här tas ett nytt grepp på kulturarvsfrågor genom att minnesskapande sätts i relation till säkerhetspolitik. Utifrån kritiska kulturarvsstudier och feministisk teori diskuteras den nationella gemenskapens gränser och vilken roll som genus och sexualitet har i berättelserna om hot och försvar.I en demokrati måste frågor om militärt våld alltid genomlysas och diskuteras. Med denna utgångspunkt granskas kulturarvets betydelse för förståelsen av hot och säkerhet. Boken uppmanar till reflektion om hur historien skrivs och om vad som krävs för att skapa trygghet.I kalla krigets spår är ett resultat av ett tvärvetenskapligt forskningsprojekt. Författarna är forskare vid Stockholms universitet och har skrivit boken tillsammans.
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