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Sökning: WFRF:(Arvidsson Eva)

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1.
  • Arvidsson, Inga, et al. (författare)
  • Ländrygg
  • 2007
  • Ingår i: Rörelseorganens funktionsstörningar - klinik och sjukgymnastik. - 9789144039541 ; , s. 219-246
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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2.
  • Arvidsson, Linnea, et al. (författare)
  • Virtual Follow up After Distal Radius Fracture Surgery — Patient Experiences During the COVID-19 Pandemic
  • 2023
  • Ingår i: Journal of Patient Experience. - Thousand Oaks, CA : Sage Publications. - 2374-3735 .- 2374-3743. ; 10
  • Tidskriftsartikel (refereegranskat)abstract
    • The majority of patients with a distal radius fracture (DRF) are elderly, a group known to experience difficulties with new technology, partly due to a low level of digital literacy. At the beginning of the coronavirus disease 2019 pandemic, during the spring 2020, patients that underwent DRF surgery had regular follow-ups replaced by video calls from their surgeon and physiotherapist. Afterward, patients answered questionnaires regarding health and digital literacy and took part in semistructured interviews regarding the experience of the virtual follow-up. By systemic text condensation, 2 major categories were identified: (1) The video call—new, but surprisingly simple: All but 1 found it easier than expected, and (2) Video calls—the patient's choice: All but 1 patient preferred video calls to physical visits for follow-up. This is the first mixed methods study to assess patients’ experiences of digital follow-up after DRF surgery. This study indicates that digital follow-up was highly appreciated, even among patients with low levels of digital literacy. Digital technologies must be made suitable even for patients with inadequate levels of digital literacy. © The Author(s) 2023.
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3.
  • Andersson, Sara, et al. (författare)
  • Rehabilitering
  • 2007
  • Ingår i: Nordisk lärobok i audiologi. - Bromma : C. A. Tegnér AB. - 9789163194405 ; , s. 325-389
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Sjukdomstillstånd och skador i organ och vävnader orsakar diverse funktionella avvikelser, som i sin tur ger upphov till symptom, som personen ifråga kan iaktta och lida av. Dessa orsakar funktionsnedsättningar, som påverkar individens möjligheter att fungera och klara sig i sin dagliga miljö hemma, i olika arbetssituationer och i olika sociala sammanhang.
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4.
  • Anell, Anders, et al. (författare)
  • Access to automated comparative feedback reports in primary care : a study of intensity of use and relationship with clinical performance among Swedish primary care practices
  • 2024
  • Ingår i: BMC Health Services Research. - : BioMed Central (BMC). - 1472-6963. ; 24:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Digital applications that automatically extract information from electronic medical records and provide comparative visualizations of the data in the form of quality indicators to primary care practices may facilitate local quality improvement (QI). A necessary condition for such QI to work is that practices actively access the data. The purpose of this study was to explore the use of an application that visualizes quality indicators in Swedish primary care, developed by a profession-led QI initiative (“Primärvårdskvalitet”). We also describe the characteristics of practices that used the application more or less extensively, and the relationships between the intensity of use and changes in selected performance indicators. Methods: We studied longitudinal data on 122 primary care practices’ visits to pages (page views) in the application over a period up to 5 years. We compared high and low users, classified by the average number of monthly page views, with respect to practice and patient characteristics as well as baseline measurements of a subset of the performance indicators. We estimated linear associations between visits to pages with diabetes-related indicators and the change in measurements of selected diabetes indicators over 1.5 years. Results: Less than half of all practices accessed the data in a given month, although most practices accessed the data during at least one third of the observed months. High and low users were similar in terms of most studied characteristics. We found statistically significant positive associations between use of the diabetes indicators and changes in measurements of three diabetes indicators. Conclusions: Although most practices in this study indicated an interest in the automated feedback reports, the intensity of use can be described as varying and on average limited. The positive associations between the use and changes in performance suggest that policymakers should increase their support of practices’ QI efforts. Such support may include providing a formalized structure for peer group discussions of data, facilitating both understanding of the data and possible action points to improve performance, while maintaining a profession-led use of applications.
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5.
  • Arne, Gabriella, et al. (författare)
  • Gastrointestinal stromal tumors (GISTs) express somatostatin receptors and bind radiolabeled somatostatin analogs.
  • 2013
  • Ingår i: Acta oncologica (Stockholm, Sweden). - 1651-226X .- 0284-186X. ; 52:4, s. 783-792
  • Tidskriftsartikel (refereegranskat)abstract
    • Background. Gastrointestinal stromal tumors (GISTs) can be effectively treated with tyrosine kinase inhibitors (TKIs). However, some patients with GIST develop drug resistance, and alternative treatment strategies are therefore needed. The aim of this study was to analyze the expression of somatostatin receptors (SSTR) in GIST as a target for peptide receptor-mediated radiotherapy (PRRT). Material and methods. Expression profiling of SSTR1-5 was performed on biopsies from 34 GISTs (16 gastric tumors, 15 small intestinal tumors, and three rectal tumors). SSTR scintigraphy ((111)In-octreotide) and measurement of (111)In activity in tumor specimens was performed in seven patients. Uptake and internalization of (177)Lu- octreotate was studied in primary cell cultures from two patients. Results. Quantitative PCR analysis showed expression of SSTR1 and SSTR2 in the majority of tumors, while SSTR3-5 were expressed at low levels. Immunohistochemical analysis confirmed the presence of SSTR1 and SSTR2 proteins in all GISTs, and SSTR3-5 in a subset of tumors. Diagnostic imaging by SSTR scintigraphy, using (111)In-octreotide, demonstrated tumor uptake of (111)In in three of six GIST patients. Measurement of (111)In activity in excised tumor specimens from five patients gave tumor-to-blood (T/B) activity ratios of between eight and 96. Tumor cells in primary culture (gastric and small intestinal GIST) specifically bound and internalized (177)Lu when incubated with the therapeutic compound (177)Lu-octreotate for 4-48 hours (p < 0.05). Conclusion. Peptide receptor-mediated radiotherapy via SSTR may provide a novel treatment strategy in carefully selected GIST patients with TKI-resistant tumors.
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8.
  • Arvidsson, Ann-Kristin, et al. (författare)
  • Tyr-716 in the platelet-derived growth factor beta-receptor kinase insertis involved in GRB2 binding and Ras activation
  • 1994
  • Ingår i: Molecular and Cellular Biology. - : American Society for Microbiology. - 0270-7306 .- 1098-5549. ; 14:10, s. 6715-6726
  • Tidskriftsartikel (refereegranskat)abstract
    • Ligand stimulation of the platelet-derived growth factor (PDGF) beta-receptor leads to activation of its intrinsic tyrosine kinase and autophosphorylation of the intracellular part of the receptor. The autophosphorylated tyrosine residues mediate interactions with downstream signal transduction molecules and thereby initiate different signalling pathways. A pathway leading to activation of the GTP-binding protein Ras involves the adaptor molecule GRB2. Here we show that Tyr-716, a novel autophosphorylation site in the PDGF beta-receptor kinase insert, mediates direct binding of GRB2 in vitro and in vivo. In a panel of mutant PDGF beta-receptors, in which Tyr-716 and the previously known autophosphorylation sites were individually mutated, only PDGFR beta Y716F failed to bind GRB2. Furthermore, a synthetic phosphorylated peptide containing Tyr-716 bound GRB2, and this peptide specifically interrupted the interaction between GRB2 and the wild-type receptor. In addition, the Y716(P) peptide significantly decreased the amount of GTP bound to Ras in response to PDGF in permeabilized fibroblasts as well as in porcine aortic endothelial cells expressing transfected PDGF beta-receptors. The mutant PDGFR beta Y716F still mediated activation of mitogen-activated protein kinases and an increased DNA synthesis in response to PDGF, indicating that multiple signal transduction pathways transduce mitogenic signals from the activated PDGF beta-receptor.
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11.
  • Arvidsson, Bo, 1962-, et al. (författare)
  • Reference data for bone mineral density in Swedish women using digital X-ray radiometry
  • 2013
  • Ingår i: Journal of clinical densitometry. - New York, USA : Elsevier. - 1094-6950 .- 1559-0747. ; 16:2, s. 183-188
  • Tidskriftsartikel (refereegranskat)abstract
    • During the last decade, digital X-ray radiometry (DXR) has been used to measure bone mineral density (BMD) in the metacarpal bones. The aim of this study was to establish Swedish reference material for bone mass in women, measured in the metacarpal bones with DXR, and compare these data with the data from the manufacturer. A sample of 1440 women aged 20-79yr living in Örebro County was randomly assigned from the population register. Microdose mammography was used (Sectra MDM L30; Sectra Imtec AB, Linköping, Sweden) to measure BMD. Cole's LMS method was used to calculate DXR. Six hundred sixty-nine (48.3%) women participated. Peak bone mass occurred at the age of 43.4yr with a BMD of 0.597g/cm(2) (standard deviation: 0.050). Our Swedish data correlated well with the manufacturer's material. Only among women aged 50-59yr did BMD differ, where the Swedish sample had lower values. The LMS method can be used to describe the DXR data and provide a more detailed picture of bone density distribution. DXR-BMD in Swedish women aged 20-79yr is equivalent to findings from other studies, showing the same distribution of BMD in most age groups except for ages 50-59yr.
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12.
  • Arvidsson, Eva, et al. (författare)
  • Conditions and barriers for quality improvement work : a qualitative study of how professionals and health centre managers experience audit and feedback practices in Swedish primary care
  • 2021
  • Ingår i: BMC Family Practice. - : BioMed Central. - 1471-2296. ; 22
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: High quality primary care is expected to be the basis of many health care systems. Expectations on primary care are rising as societies age and the burden of chronic disease grows. To stimulate adherence to guidelines and quality improvement, audit and feedback to professionals is often used, but the effects vary. Even with carefully designed audit and feedback practices, barriers related to contextual conditions may prevent quality improvement efforts. The purpose of this study was to explore how professionals and health centre managers in Swedish primary care experience existing forms of audit and feedback, and conditions and barriers for quality improvement, and to explore views on the future use of clinical performance data for quality improvement.Methods: We used an explorative qualitative design. Focus groups were conducted with health centre managers, physicians and other health professionals at seven health centres. The interviews were audio recorded, transcribed and analysed using qualitative content analysis.Results: Four different types of audit and feedback that regularly occurred at the health centres were identified. The main part of the audit and feedback was “external”, from the regional purchasers and funders, and from the owners of the health centres. This audit and feedback focused on non-clinical measures such as revenues, utilisation of resources, and the volume of production. The participants in our study did not perceive that existing audit and feedback practices contributed to improved quality in general. This, along with lack of time for quality improvement, lack of autonomy and lack of quality improvement initiatives at the system (macro) level, were considered barriers to quality improvement at the health centres.Conclusions: Professionals and health centre managers did not experience audit and feedback practices and existing conditions in Swedish primary care as supportive of quality improvement work. From a professional perspective, audit and feedback with a focus on clinical measures, as well as autonomy for professionals, are necessary to create motivation and space for quality improvement work. Such initiatives also need to be supported by quality improvement efforts at the system (macro) level, which favour transformation to a primary care based system.
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  • Arvidsson, Eva, et al. (författare)
  • Core Values of Family Medicine in Europe : Current State and Challenges
  • 2021
  • Ingår i: Frontiers in Medicine. - : Frontiers Media S.A.. - 2296-858X. ; 8
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Values are deeply held views that act as guiding beliefs for individuals and organizations. They state what is important in a profession. The aims of this study were to determine whether European countries have already developed (or are developing) documents on core values in family medicine; to gather the lists of core values already developed in countries; and to gather the opinions of participants on what the core family values in their countries are.Methods: This was a qualitative study. The questionnaire was distributed as an e-survey via email to present and former members of the European Society for Quality and Safety in Family Practice (EQuiP), and other family medicine experts in Europe. The questionnaire included six items concerning core values in family medicine in the respondent's country: the process of defining core values, present core values, the respondents' suggestions for core values, and current challenges of core values.Results: Core values in family medicine were defined or in a process of being defined in several European countries. The most common core values already defined were the doctor-patient relationship, continuity, comprehensiveness and holistic care, community orientation, and professionalism. Some countries expressed the need for an update of the current core values' list. Most respondents felt the core values of their discipline were challenged in today's world. The main values challenged were continuity, patient-centered care/the doctor-patient relationship and comprehensive and holistic care, but also prioritization, equity, and community orientation and cooperation. These were challenged by digital health, workload/lack of family physicians, fragmentation of care, interdisciplinary care, and societal trends and commercial interests.Conclusion: We managed to identify suggestions for core values of family medicine at the European level. There is a clear need to adopt a definition of a value and tailor the discussion and actions on the family medicine core values accordingly. There is also a need to identify the core values of family medicine in European countries. This could strengthen the profession, promote its development and research, improve education, and help European countries to advocate for the profession.
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  • Arvidsson, Eva, et al. (författare)
  • Day-to-day Rationing of Limited Resources in Swedish routine Primary Care : an interview study
  • 2013
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Rationing is a reality in all health care, but little is known about day-to-day rationing in routine primary health care (PHC). This study aims to explore strategies to handle limited of resources in Swedish routine primary care.Methods: Data were compiled from 62 interviews with healthcare professionals (general practitioners, nurses, physiotherapists, and managers at primary care centres). A qualitative research method was applied in the analysis.Results: The interviewed staff described perceptions of a general public with high expectations on PHC in combination with a lack of resources. Strategies to cope with scarce resources were avoiding rationing, ad hoc rationing, or planned rationing. Rationing was largely implicit and not based on ethical principles or other defined criteria. Trying to avoid rationing resulted in unintended rationing. Ad hoc rationing had undesired consequences, e.g. inadequate continuity of care and displacing certain patient groups, especially the chronically ill and the elderly. The staff expressed a need for support and for applicable guidelines, and called for policy statements based on priority decisions to help manage the situation.Conclusions: The interviews suggested a need to improve the transparency of priority setting procedures in PHC, although the nature of the PHC setting presents special challenges. Improving transparency could, in turn, improve equity and the efficient use of resources in PHC.
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16.
  • Arvidsson, Eva, 1951- (författare)
  • Elleholm
  • 1984
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • The aim of the project: This report on the situation of urban archaeology in Elleholm is written as part of the project The Medieval Town: Implications of Early Urbanization for Modem Planning, under the auspices of Riksantikvarieämbetet och statens historiska museer. The aim of the project is to make a detailed survey and documentation of the situation of urban archaeology and its implications for physical planning and make a scholarly evaluation of the uncovered material. The project deals mainly with those places which obtained town rights in the formal legal sense during the Middle Ages.The arrangement of the report: Chapters 1 and 2 give an account of a number of data which in various ways are important for the early development of the town. The information is collected from available literature (mainly as regards documentary material) as well as from primary material in the archives (archaeological data, records from borings). In the firstmentioned case no attempt has been made to correct possible faults through independent research. As regards the archaeological material, the aim has been to include all archaeological observations, even if for different reasons this has not always been possible.One important aim during work on the report has been to appraise and evaluate the archaeological material and to what extent it throws light on essential problems concerning urban history. The basic idea is that archaeological material can provide information about chronology, function, social structure and economic bases. The material has been arranged on the assumption that the form of settlement which took place and is reflected in the archaeological material is the result of a functional adaption to certain decisive prerequisites such as topography, communications, and economical-geographical conditions.The data have been chosen and structured on this basis. The selection gives both a general view of the available material concerning the development of the medieval town and a basis for further work on this material. This in turn will provide a foundation for the antiquarian evaluation in relation to future work.The English summary gives a broad outline of the contents, mainly based on the maps of the report. […] 
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20.
  • Arvidsson, Eva, et al. (författare)
  • Measuring quality in primary healthcare - Opportunities and weaknesses
  • 2019
  • Ingår i: Zdravstveno Varstvo. - : National Institute of Public Health. - 0351-0026 .- 1854-2476. ; 58:3, s. 101-103
  • Tidskriftsartikel (refereegranskat)abstract
    • The easy access to data from electronic patient records has made using this type of data in pay-for performance systems increasingly common. General practitioners (GPs) throughout Europe oppose this for several reasons. Not all data can be used to derive good quality indicators and quality indicators can’t reflect the broad scope of primary care. Qualities like person-centred care and continuity are particularly difficult to measure. The indicators urge doctors and nurses to spend too much time on the registration and administration of required data. However, quality indicators can be very useful as starting points for discussions about quality in primary care, with the purpose being to initiate, stimulate and support local improvement work. This led to The European Society for Quality and Patient Safety in General Practice (EQuiP) feeling the urge to clarify the different aspects of quality indicators by updating their statement on measuring quality in Primary Care. The statement has been endorsed by the Wonca Europe Council in 2018.
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  • Arvidsson, Eva, et al. (författare)
  • Primary care patients' attitudes to priority setting in Sweden
  • 2009
  • Ingår i: Scandinavian Journal of Primary Health Care. - : Informa UK Limited. - 0281-3432 .- 1502-7724. ; 27:2, s. 123-128
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective. To analyse attitudes to priority setting among patients in Swedish primary healthcare. Design. A questionnaire was given to patients comprising statements on attitudes towards prioritizing, on the role of politicians and healthcare staff in prioritizing, and on patient satisfaction with the outcome of their contact with primary healthcare (PHC). Settings. Four healthcare centres in Sweden, chosen through purposive sampling. Participants. All the patients in contact with the health centres during a two-week period in 2004 (2517 questionnaires, 72% returned). Main outcomes. Patient attitudes to priority setting and satisfaction with the outcome of their contact. Results. More than 75% of the patients agreed with statements like Public health services should always provide the best possible care, irrespective of cost. Almost three-quarters of the patients wanted healthcare staff rather than politicians to make decisions on priority setting. Younger patients and males were more positive towards priority setting and they also had a more positive view of the role of politicians. Less than 10% of the patients experienced some kind of economic rationing but the majority of these patients were satisfied with their contact with primary care. Conclusions. Primary care patient opinions concerning priority setting are a challenge for both politicians and GPs. The fact that males and younger patients are less negative to prioritizing may pave the way for a future dialogue between politicians and the general public.
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  • Arvidsson, Eva, 1959- (författare)
  • Prioritering i primärvården
  • 2022
  • Ingår i: Prioriteringscentrum - 20 år i rättvisans tjänst. - Linköping : Linköping University Electronic Press. - 9789179294144 ; , s. 119-125
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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25.
  • Arvidsson, Eva (författare)
  • Priority Setting and Rationing in Primary Health Care
  • 2013
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Studies on priority setting in primary health care are rare. Priority setting and rationing in primary health care is important because outcomes from primary health care have significant implications for health care costs and outcomes in the health system as a whole.Aims: The general aim of this thesis has been to study and analyse the prerequisites for priority setting in primary health care in Sweden. This was done by exploring strategies to handle scarce resources in Swedish routine primary health care (Paper I); analysing patients’ attitudes towards priority setting and rationing and patients’ satisfaction with the outcome of their contact with primary health care (Paper II); describing and analysing how general practitioners, nurses, and patients prioritised individual patients in routine primary health care, studying the association between three key priority setting criteria (severity of the health condition, patient benefit, and cost-effectiveness of the medical intervention) and the overall priority assigned by the general practitioners and nurses to individual patients (Paper III); and analysing how the staff, in their clinical practise, perceived the application of the three key priority setting criteria (Paper IV).Methods: Both qualitative (Paper I and IV) and quantitative (Paper II and III) methods were used. Paper I was an interview study with medical staff at 17 primary health care centres. The data for Paper II and Paper III were collected through questionnaires to patients and staff at four purposely selected health care centres during a 2-week period. Paper IV was a focus group study conducted with staff members who practiced priority setting in day-to-day care.Results: The process of coping with scarce resources was categorised as efforts aimed to avoid rationing, ad hoc rationing, or planned rationing. Patients had little understanding of the need for priority setting. Most of them did not experience any kind of rationing and most of those who did were satisfied with the outcome of their contact with primary health care. Patients, compared to medical staff, gave relatively higher priority to acute/minor conditions than to preventive check-ups for chronic conditions when prioritising individual patients in day-today primary health care. When applying the three priority setting criteria in day-to-day primary health care, the criteria largely influenced the overall prioritisation of each patient. General practitioners were most influenced by the expected cost-effectiveness of the intervention and nurses were most influenced by the severity of the condition. Staff perceived the criteria as relevant, but not sufficient. Three additional aspects to consider in priority setting in primary health care were identified, namely viewpoint (medical or patient’s), timeframe (now or later) and evidence level (group or individual).Conclusion: There appears to be a need for, and the potential to, introduce more consistent priority setting in primary health care. The characteristics of primary health care, such as the vast array of health problems, the large number of patients with vague symptoms, early stages of diseases, and combinations of diseases, induce both special possibilities and challenges.
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  • Arvidsson, Eva, et al. (författare)
  • Priority setting in primary health care - dilemmas and opportunities: a focus group study
  • 2010
  • Ingår i: BMC Family Practice. - : BioMed Central. - 1471-2296. ; 11:71
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Swedish health care authorities use three key criteria to produce national guidelines for local priority setting: severity of the health condition, expected patient benefit, and cost-effectiveness of medical intervention. Priority setting in primary health care (PHC) has significant implications for health costs and outcomes in the health care system. Nevertheless, these guidelines have been implemented to a very limited degree in PHC. The objective of the study was to qualitatively assess how general practitioners (GPs) and nurses perceive the application of the three key priority-setting criteria. Methods: Focus groups were held with GPs and nurses at primary health care centres, where the staff had a short period of experience in using the criteria for prioritising in their daily work. Results: The staff found the three key priority-setting criteria (severity, patient benefit, and cost-effectiveness) to be valuable for priority setting in PHC. However, when the criteria were applied in PHC, three additional dimensions were identified: 1) viewpoint (medical or patients), 2) timeframe (now or later), and 3) evidence level (group or individual). Conclusions: The three key priority-setting criteria were useful. Considering the three additional dimensions might enhance implementation of national guidelines in PHC and is probably a prerequisite for the criteria to be useful in priority setting for individual patients.
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27.
  • Arvidsson, Eva, et al. (författare)
  • Quality improvement in daily work in primary care
  • 2019
  • Konferensbidrag (refereegranskat)abstract
    • Primary health centres (PHCs) nowadays have access to data feed-back through different sources. However, while some HCSs are constantly running improvement projects others don’t use feed-back data. A national system for the audit and feed-back, Primary Care Quality, is now introduced in Sweden. Increased knowledge aboutthe reasons behind the different use of audit and feed-back data at different PHCs would be helpful help to improve conditions for use of data for quality improvement. Focus group interviews were conducted with staff and management teams at primary care centres in Sweden during. Data was analysed using qualitative content analysis. Preliminary results are three main themes that describes different approaches to quality improvement in daily practice. Each theme represents a quality improvement strategy with specifik characteristics. The three themes can be described on an axis from simple to complicated to complex.
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  • Arvidsson, Eva, et al. (författare)
  • Quality indicators : From useless to useful
  • 2020. - Europe Edition
  • Ingår i: The world book of family medicine. - Ljubljana : World Organization of Family Doctors - Europe (WONCA Europe). - 9789610703075 ; , s. 60-62
  • Bokkapitel (refereegranskat)
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  • Arvidsson, Eva, et al. (författare)
  • Quality indicators – sometimes useful sometimes not!
  • 2019
  • Konferensbidrag (refereegranskat)abstract
    • Quality indicators can be very useful as a starting point for quality improvement work. However, using quality indicators for pay for performance, seems to have mainly negative consequences. In order to clarify this EQuiP updated their policy paper on quality indicators, which was recently endorsed by Wonca Europe. The positive side of indicators, using them for quality improvement, is exemplified by ”Primary Care Quality”, a Swedish system for quality improvement in primary care.In this workshop, a brief background to EQuiP’s policy paper is presented. Thereafter ”Primary Care Quality” is introduced.Together, the participants will discuss different use of quality indicators with focus on How the Position paper can be applied in their context How indicators for quality improvement can help quality improvement (by testing ”cases” from Swedish health care centres).Finally, we summarize our experience of working with quality indicators and discuss what we can do to facilitate the positive use of them.
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32.
  • Arvidsson, Eva, et al. (författare)
  • Setting priorities in primary health care - on whose conditions? A questionnaire study
  • 2012
  • Ingår i: BMC Family Practice. - : BioMed Central. - 1471-2296. ; 13:114
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: In Sweden three key criteria are used for priority setting: severity of the health condition; patient benefit; and cost-effectiveness. They are derived from the ethical principles established by the Swedish parliament 1997 but have been used only to a limited extent in primary care. The aim of this study was to describe and analyse: 1) GPs, nurses, and patients prioritising in routine primary care 2) The association between the three key priority setting criteria and the overall priority assigned by the GPs and nurses to individual patients. less thanbrgreater than less thanbrgreater thanMethods: Paired questionnaires were distributed to all patients and the GPs or nurses they had contact with during a 2-week period at four health centres in Sweden. The staff registered the health conditions or health problem, and the planned intervention. Then they estimated the severity of the health condition, the expected patient benefit, and the cost-effectiveness of the planned intervention. Both the staff and the patients reported their overall prioritisation of the patient. In total, 1851 paired questionnaires were collected. less thanbrgreater than less thanbrgreater thanResults: Compared to the medical staff, the patients assigned relatively higher priority to acute/minor conditions than to preventive check-ups for chronic conditions. Severity of the health condition was the priority setting criterion that had the strongest association with the overall priority for the staff as a whole, but for the GPs it was cost-effectiveness. less thanbrgreater than less thanbrgreater thanConclusions: The challenge for primary care providers is to balance the patients demands with medical needs and cost-effectiveness. Transparent priority setting in primary care might contribute to a greater consensus between GPs and nurses on how to use the key priority setting criteria.
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  • Arvidsson, Eva, 1959-, et al. (författare)
  • Så resonerar läkare och sjuksköterskor vid prioriteringar av patienter i primärvård
  • 2007
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Studier av prioriteringar i primärvården är särskilt intressanta eftersom det är där de allra flesta av oss kommer i kontakt med hälso- och sjukvården. Det är också i primärvården prioriteringar och olika former av ransonering på grund av begränsade resurser är vanliga. De allra flesta av oss förstår och accepterar att vi inte omedelbart kan få träffa en läkare om det inte rör sig om akuta och allvarliga sjukdomstillstånd. Vi finner många gånger ett råd om egenvård som en tillfredställande lösning för tillfället. Hur olika prioriteringar görs ”bakom kulisserna” är dock många gånger oklart för oss. Vi kan ibland t.ex. undra varför vi får betala för vissa vårdtjänster medan andra är gratis. Osäkerhet om på vilka grunder prioriteringar sker gäller inte bara för patienter utan även sjukvårdspersonal. Erfarenheter från flera olika håll i Sverige pekar på att de etiska riktlinjer som utgör kärnan i riksdagens prioriteringsprinciper är svåra att använda i praktiken. Det är därför angeläget att få mer kunskap om hur prioriteringsprinciper och begrepp uppfattas av sjukvårdspersonalen för att utveckla arbetsformer som är begripliga och förenliga med rådande rutiner.Distriktsläkare, mottagningssköterskor och distriktssköterskor vid fyra vårdcentraler som tidigare deltagit i en prioriteringsstudie har inbjudits att diskutera prioriteringar utifrån ett antal frågeställningar. Resultaten från dessa diskussioner visar bland att olika begrepp tolkas på många olika sätt. En framgångsrik implementering av den etiska plattformen kräver antagligen betydligt mer av öppna diskussioner om prioriteringar och principer i det dagliga vårdarbetet.Två allmänläkare Eva Arvidsson från Kalmar och Malin André från Falun har bidragit med den största insatsen i projektet som för övrigt inbegriper Lars Borgquist från Avdelningen för allmänmedicin vid Linköpings universitet och Kjell Lindström från Primärvårdens utvecklingsenhet i Jönköping. Studien har finansierats av Forskningsrådet för sydöstra sjukvårdsregionen (FORSS).Jag vill på projektgruppens vägnar tacka alla medverkande från vårdcentralerna Lindsdal och Borgholm i Kalmar läns landsting, Öxnehaga i Jönköpings läns landsting och Ryds vårdcentral i Landstinget i Östergötland.Linköping 2007-07-24Per Carlsson
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34.
  •  
35.
  • Arvidsson, Eva, 1959-, et al. (författare)
  • Vägen framåt
  • 2013
  • Ingår i: Att välja rättvist. - Lund : Studentlitteratur AB. ; , s. 207-214
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Som vi visat har utvecklingen av metoder och strukturer för öppna prioriteringar i Sverige kommit långt. Många frågor återstår likväl. Under vårt arbete med denna bok har vi identifierat ett antal förbättringsområden och utmaningar som vi avslutningsvis vill lyfta fram. Det rör sig om vilka som ska delta i prioriteringarna, tydliggörande av värdegrunden, behov av bättre kunskap, baserad på både vetenskaplig metod och erfarenhet, och fortsatt utveckling av prioriteringsprocesser på olika nivåer och i olika sammanhang. Även om vi i Sverige skulle nå en god enighet kring principer och kriterier för prioriteringar så kommer vi alltid finna många olika sätt att praktiskt lösa specifika prioriteringsproblem.
  •  
36.
  • Arvidsson, Marcus, et al. (författare)
  • Organizational climate in air traffic control
  • 2002
  • Ingår i: European Academy of Occupational Health Psychology conference proceedings series. - 1473-0200. ; , s. 24-27
  • Konferensbidrag (refereegranskat)abstract
    • A positive and innovative organizational climate is of great importance in order to manage and adapt to change. Such a climate seldom evolves in organizations closely governed by rules and regulations. Because of ongoing organizational and technical changes within the Swedish Air Navigation Services Provider, a study concerning the organizational climate for changes and innovations was conducted to investigate the organization’s capacity to cope with changes. Study locations were the two Swedish main air traffic control centers and parts of the civil aviation administration headquarters. 390 subjects took part in the study and the CCQ questionnaire was used to measure the organizational climate. The results show that the organizational climate is quite positive despite the rule governed work. The results also show that administrative personnel assess the organizational climate as more positive than operative personnel. Comparisons between management positions did not result in any differences.
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37.
  • Arvidsson, Per-Ola, et al. (författare)
  • Purification and identification of the violaxanthin de-epoxidase as a 43 kDa protein
  • 1996
  • Ingår i: Photosynthesis Research. - 0166-8595. ; 49:2, s. 119-129
  • Tidskriftsartikel (refereegranskat)abstract
    • Violaxanthin deepoxidase (VDE) has been purified from spinach (Spinacia oleracea) leaves. The purification included differential sonication of thylakoid membranes, differential (NH4)2SO4 fractionation, gel filtration chromatography and finally either hydrophobic interaction chromatography or anion exchange chromatography. A total purification of more than 5000-fold compared to the original thylakoids enabled the identification of a 43 kDa protein as the VDE, in contrast to earlier reported molecular weight of 54–60 kDa. A detailed comparison was made for the VDE activity and polypeptide pattern for the different fractions throughout the purification and the best correlation was always found for the 43 kDa protein. The highest specific activity obtained was 256 mol g–1 s–1 protein, which is at least 10-fold higher than reported earlier. We estimate that there is 1 VDE molecule per 20–100 electron transport chains. The 43 kDa protein was N-terminally sequenced, after protection of cysteine residues with -mercaptoethanol and iodoacetamid, and a unique sequence of 20 amino acids was obtained. The amino acid composition of the protein revealed a high abundance of charged and polar amino acids and remarkably, 11 cysteine residues. Two other proteins (39.5 kDa and 40 kDa) copurifying with VDE were also N-terminally sequenced. The N-terminal part of the 39.5 kDa protein showed complete sequence identity both with the N-terminal part of cyt b 6 and an internal sequence of polyphenol oxidase.
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38.
  • Arvidsson, Sandra, 1986- (författare)
  • Cardiac function in hereditary transthyretin amyloidosis : an echocardiographic study
  • 2016
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Hereditary transthyretin amyloidosis (ATTR) is a lethal disease in which misfolded transthyretin (TTR) proteins accumulate as insoluble aggregates in tissues throughout the body. A common mutation is the exchange of valine to methionine at place 30 (TTR V30M), a form endemically found in the northern parts of Sweden. The main treatment option for ATTR amyloidosis is liver transplantation as the procedure halts production of mutated transthyretin. The disease is associated with marked phenotypic diversity ranging from predominant cardiac complications to pure neuropathy. Two different types of fibril composition – one in which both fragmented and full-length TTR are present (type A) and one consisting of only full-length TTR (type B) have been suggested to account for some phenotypic differences. Cardiac amyloidosis is associated with increased myocardial thickness and the disease could easily be mistaken for other entities characterised by myocardial thickening, such as sarcomeric hypertrophic cardiomyopathy (HCM). The aims in this thesis were to investigate echocardiographic characteristics in Swedish ATTR amyloidosis patients, and to identify markers aiding in differentiating ATTR heart disease from HCM. Another objective was to examine the impact of fibril composition and sex on the phenotypic variation in amyloid heart disease.Methods: A total of 122 ATTR amyloidosis patients that had undergone thorough echocardiographic examinations were included in the studies. Analyses of ventricular geometry as well as assessment of systolic and diastolic function were performed, using both conventional echocardiographic methods and speckle tracking technique. ECG analysis was conducted in study I, allowing measurement of QRS voltage. In study I and study II ATTR patients were compared to patients with HCM. In addition, 30 healthy controls were added to study II.Results: When parameters from ECG and echocardiography were investigated, the results revealed that the combination of QRS voltage <30 mm (<3 mV) and an interventricular/posterior wall thickness quotient <1.6 could differentiate cardiac ATTR amyloidosis from HCM. Differences in degree of right ventricular involvement were also demonstrated between HCM and ATTR amyloidosis, where ATTR patients displayed a right ventricular apical sparing pattern whereas the inverse pattern was found in HCM. Analysis of fibril composition revealed increased LV wall thickness in type A patients compared to type B, but in addition type A women displayed both lower myocardial thickness and more preserved systolic function as compared to type A males. When cardiac geometry and function were evaluated pre and post liver transplantation in type A and B patients, significant deterioration was detected in type A but not in type B patients after liver transplantation.Conclusions: Increasing awareness of typical cardiac amyloidotic signs by echocardiography is important to reduce the risk of delayed diagnosis. Our classification model based on ECG and echocardiography could aid in differentiating ATTR amyloidosis from HCM. Furthermore, the apical sparing pattern found in the right ventricle may pose another clue for amyloid heart disease, although it requires to be studied further. Furthermore, we disclosed that type A fibrils, male sex and increasing age were important determinants of increased myocardial thickness. As type A fibril patients displayed rapid cardiac deterioration after liver transplantation other treatment options should probably be sought for this group of patients.
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39.
  • Axelsson, Ulrik, et al. (författare)
  • Strukturerad miljödatahantering inom järn- och stålindustri
  • 2002
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Efterfrågan på miljöinformation i olika former förväntas öka under de kommande åren. Det gäller såväl internt inom företaget som externt till kunder, ägare, övriga finansiärer, myndigheter m.fl. För att kunna möta de förväntade kraven har företagen inom järn- och stålindustrin identifierat ett behov av att åstadkomma en strukturerad miljödatahantering (lagring, bearbetning och dokumentation), som möjliggör att ett och samma dataunderlag så långt som möjligt kan utnyttjas och relativt enkelt omformas till olika former av kommunikationsprodukter. Projektets mål är därför att ta fram en branschgemensam struktur för miljödatahantering inom järn- och stålindustrin
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40.
  • Axelsson, Ulrik, et al. (författare)
  • Strukturerad miljödatahantering inom järn- och stålindustri. Etapp 2; Miljöinformationssystem
  • 2004
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Det analysarbete som gjorts har i denna etapp har genomförts i samarbete med samma tre typföretag - Höganäs AB, Sandvik Materials Technology samt Ovako Steel AB - som i etapp 1. De tre företagen hanterar vardera en avsevärda mängd miljödata som idag finns utspridd inom organisationerna och lagras i olika system varför sammanställningar försvåras. Det betyder att den miljödata som mäts och beräknas lagras på ett sätt som innebär en irrationell hantering av den samlade miljöinformationen. Den analys som visar att det inom järn- och stålbranschen går att beskriva verksamhetsprocesser på ett enhetligt sätt och att miljödatan som företagen mäter, beräknar och lagrar överensstämmer i mycket stor grad. Baserat på detta har en branschgemensam miljödatastruktur varit möjlig att ta fram. Denna struktur är framtagen för att kunna lagra miljödata för utsläpp till luft, utsläpp till vatten, energianvändning och avfall. Utifrån den miljödatastruktur som arbetats fram och genom diskussioner med representanter för typföretagen i projektet har en översiktlig systemskiss för ett miljöinformationssystem inom järn- och stålindustrin tagits fram. Detta miljöinformationssystem kan vara generellt inom branschen och svara upp mot gemensamma krav på hantering av miljödata.
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41.
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42.
  • Bergqvist, Björn, 1965, et al. (författare)
  • Effect of microwave radiation on permeability of liposomes. Evidence against non-thermal leakage
  • 1994
  • Ingår i: Biochimica et Biophysica Acta - General Subjects. - : Elsevier BV. - 1872-8006 .- 0304-4165. ; 1201:1, s. 51-54
  • Tidskriftsartikel (refereegranskat)abstract
    • The effect of 2.45 GHz microwave radiation on the permeability of unilamellar phosphatidylcholine liposomes has been studied. Leakage of 5(6)-calboxyfluorescein from the liposomes was measured using spectrofluorimetry after exposure to either microwaves or thermal heating for 5-20 min intervals. The exposure temperature, 37.6 +/- 0.5 degrees C, was well above the phase transition temperature of the lipid membrane. The microwave exposure did not result in any non-thermal increase in permeability above that produced by thermal heating. This study refutes the results reported by Saalman et al. [1] in which an increased liposome permeability due to microwave exposure was reported. The refined analysis in the present study shows that this increased liposome permeability was not a non-thermal microwave effect.
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43.
  • Bergström, Eva-Lena, 1961- (författare)
  • Nationalmuseum i offentlighetens ljus : framväxten av tillfälliga utställningar 1866-1966
  • 2018
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The purpose of this study is to investigate the emergence of temporary exhibitions at the Nationalmuseum of Sweden 1866–1966. My aim is to discuss and place the exhibitions in the complex ongoing tension between the role of the museum as a scientific and an educative public institution, and in relation to the permanent collection. This I have called the museum dilemma. The dissertation is divided in three main chapters put in a chronological order 1866–1913, 1914–1939 and 1940–1966.   I have found that during the 1866–1913 period many minor temporary exhibitions were arranged. It seems to have been a practice of coincidences rather than strategic art historical considerations. There were not many exhibitions focusing on art historical narratives. This situation reflects that the main reasons for arranging temporary exhibitions were to complement the museum collection or to present interesting art objects normally hidden from the public view.When the term “temporary exhibition” was established in the late 19th century a tension between the exhibitions and the permanent collection was established. The temporary exhibitions were associated with variety and flexibility while the permanent collection indicated a static art historical narrative.The 1914–1939 period was very socially inclined. There are many examples of exhibitions that openly supported national values and the ongoing democracy development and the exhibition practice developed in dialog with the museum´s collection. The concept “bringing art alive” was frequently used. The museum collections were talked about as dead material, the museum was called a morgue.   During the Second World War, the collections were evacuated from the museum building and an innovative period began. A focus on art history dominates the more elaborated exhibition practice during 1939–1966 period, so called “epoch exhibitions”. They invited to innovative actions, technologies as reconstructions of historical exhibitions, mixed materials and rehanging during the exhibition period. Principles as flexibility and variation were prominent. Another common denominator was the scientific focus and the idea that the exhibition is both an experience and a source of knowledge.   Even though half a century has passed I argue that the results I have found can be related to the museum practice of today. The tendency today is that temporary exhibitions functions as role models for museums, when re-organizing the permanent collections. The effect of this development is that the categories temporary exhibitions and permanent collection melt together. In that sense, I would also suggest that the term temporary exhibition should be replaced. Special exhibition seems to be a more appropriate term for the museums of today.
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44.
  • Borgquist, Lars, 1944-, et al. (författare)
  • Tankar om medicinsk kunskapsutveckling, prioriteringar och svensk primärvårdsorganisation
  • 2016
  • Ingår i: Perspektiv på utvärdering, prioritering, implementering och hälsoekonomi. - Linköping : Linköpings universitet. - 9789176857441 ; , s. 7-17
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Den medicinska kunskapsutvecklingen har genomgått stora förändringar under de senaste femtio åren. Den ökade kunskapen har påverkat arbetsfördelningen mellan sjukhusvård och primärvård. Dessutom har flera vårdorganisatoriska reformer ägt rum under denna tid. Exempelvis övertogs ansvaret för allmänläkarverksamheten av landstingen från staten 1963. År 1970 hade Sverige högst andel av antalet slutenvårdsplatser i Europa. Samma år ändrades ersättningssystemet för läkare till en fast lön. Fyrtio år senare var andelen slutenvårdsplatser lägst i Europa. Under denna tidsperiod ökade antalet vårdcentraler från ett tjugotal till cirka 1200. Omfördelningen från sjukhusvård till primärvård och öppna vårdformer har liksom den medicinska kunskapsutvecklingen haft konsekvenser för relationerna mellan sjukhus och primärvård. Primärvård har traditionellt definierats med ett organisatoriskt perspektiv medan sjukhusspecialiteter i huvudsak har definierats från ett medicinskt kunskapsområde (1). Men både primärvård och sjukhusspecialiteter har ansvar för medicinska problem på låg och hög kunskapsnivå.
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45.
  • Bratt, Charlotte Eva, et al. (författare)
  • Regulation of violaxanthin de-epoxidase activity by pH and ascorbate concentration
  • 1995
  • Ingår i: Photosynthesis Research. - 0166-8595. ; 45:2, s. 169-175
  • Tidskriftsartikel (refereegranskat)abstract
    • The activity of violaxanthin de-epoxidase has been studied both in isolated thylakoids and after partial purification, as a function of pH and ascorbate concentration. We demonstrate that violaxanthin de-epoxidase has a Km for ascorbate that is strongly dependent on pH, with values of 10, 2.5, 1.0 and 0.3 mM at pH 6.0, 5.5, 5.0 and 4.5, respectively. These values can be expressed as a single Km±0.1±0.02 mM for the acid form of ascorbate. Release of the protein from the thylakoids by sonication was also found to be strongly pH dependent with a cooperativity of 4 with respect to protons and with an inflexion point at pH 6.7. These results can explain some of the discrepancies reported in the literature and provide a more consistent view of zeaxanthin formation in vivo.
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46.
  • Broqvist, Mari, 1958-, et al. (författare)
  • Prioriteringar initierade på verksamhetsnivå
  • 2013. - 1:1
  • Ingår i: Att välja rättvist. - Lund : Studentlitteratur. - 9789144083933 ; , s. 189-206
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Den här boken är avsedd som ett stöd för alla som vill ge sig i kast med frågan om prioriteringar i hälso- och sjukvården. Den diskuterar orsakerna till att riksdagsbeslutet om prioriteringar inte genomförts i hälso- och sjukvården, trots att de etiska principer som prioriteringsordningen vilar på är djupt förankrade hos både vårdpersonal och befolkningen i övrigt. Vidare diskuteras grundläggande begrepp i sammanhanget liksom hälso- och sjukvårdens roll i förhållande till ohälsa och sjukdom i befolkningen. I boken betonas vikten av att många erfarenheter och perspektiv möts i dialogen kring prioriteringsfrågorna. En rad olika metoder och erfarenheter som kan underlätta det gemensamma arbetet presenteras också.Boken är avsedd som ett diskussionsunderlag för de som leder eller deltar i prioriteringssammanhang i landstingens och kommunernas hälso- och sjukvård. Den kan också användas i utbildningen av hälso- och sjukvårdspersonal.
  •  
47.
  •  
48.
  • Börjesson, Peter, 1980, et al. (författare)
  • The Merits of Situated Evaluation as an Alternative UX Evaluation Method to Understand Appropriation
  • 2018
  • Ingår i: Interaction Design and Architecture(s). - 2283-2998 .- 1826-9745. ; :37, s. 78-98
  • Tidskriftsartikel (refereegranskat)abstract
    • Oftentimes, technologies are not used in the ways designers had initially envisioned. Instead, people adapt technologies to their own needs, a phenomenon called ‘appropriation’. Appropriation is an important aspect of User Experience design, related to the situatedness and dynamics of the design, recognizing not only that initial needs and requirements may change over time, but also that a design may change the environment that it was designed for. Appropriation can also contribute to a sense of ownership as people use a design in their own way, sometimes in ways the designer did not intend. However, commonly used User Experience evaluation methods often do not focus on the appropriation process of a technology. Situated Evaluation is an approach that does focus on appropriation, although it has not yet been used extensively in the UX field. In this paper, we therefore present and critically discuss our use of the Situated Evaluation approach for the evaluation of a specific tool that aims to enhance the communication between children, parents, and teaching staff in special education. By presenting this case, we hope to inform other UX researchers and designer about the potential of the approach to understand appropriation is an important factor in UX design.
  •  
49.
  •  
50.
  • Clausson, Eva, 1952-, et al. (författare)
  • Omsorg efter trauma
  • 2020
  • Ingår i: Skolhälsan. ; :4, s. 26-27
  • Tidskriftsartikel (populärvet., debatt m.m.)
  •  
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