| 1. |
- Bourdieu, Pierre, et al.
(författare)
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Leve idrottspedagogiken : En vänbok tillägnad Lars-Magnus Engström
- 2005
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Vem ägnar sig åt idrott? Vilken betydelse har fritiden i barns och ungdomars liv? Vad innebär hälsa i skolämnet idrott och hälsa?Leve idrottspedagogiken! tillägnas Lars-Magnus Engström. Texterna i boken speglar delar av det idrottspedagogiska forskningsområdet i Sverige, vars framväxt Lars-Magnus Engström varit den främste företrädaren för. Läsaren får här ta del av exempelvis idrottskulturen, fritidskulturen och skolans ämne idrott och hälsa. Genomgående handlar texterna om villkoren för barns och ungdomars deltagane och om de olika lärprocesser som sker i anslutning till idrottsutövning.Lars-Magnus Engström har gjort betydande insatser som forskare och lärare samt som professor vid Lärarhögskolan i Stockholm och vid Gymnastik- och idrottshögskolan. I snart fyrtion år har han arbetat med studier kring påverkans- och lärprocesser i idrott. Hans forskning har främst kretsat kring människors idrottsvanor och vilka som utvecklar en fysiskt aktiv livsstil. Idrotts- och motionsutövningar ger både ett så kallat egenvärde och investeringsvärde. Med dessa begrepp bland många andra har Lars-Magnus Engström bidragit till en fördjupad vetenskaplig förståelse av idrottskulturen.De flesta författarna har eller har haft Lars-Magnus Engström som handledare och tillhör forskningsgruppen för pedagogik, idrott och fritidskultur. Redaktörer för boken är Karin Redelius och Håkan Larsson.
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| 2. |
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| 3. |
- Bäckström, Ingela, 1963-
(författare)
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On the Relationship between Sustainable Health and Quality Management : Leadership and organizational behaviours from Swedish organizations
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Sickness absence not only causes significant costs for organizations but also leads to other negative consequences for individuals and societies. Previous research has shown that working with organizational values within Quality Management affects job satisfaction and results in increased profitability and customer satisfaction. There would, in addition, seem to be great gains if managers, by working with Quality Management, can manage to establish sustainable health among co-workers. The purpose of the research described in this thesis was to examine how Quality Management could be practised in order to support sustainable health among co-workers and what it is within Quality Management that influences sustainable co-worker health. Accordingly, the purpose was also to contribute to the understanding of the relation between sustainable health and Quality Management. To fulfil this purpose, three research questions were asked. The results are described in three parts related to the three research questions and are the product of six case studies carried out in seven different organizations. Interviews with managers and workshops with co-workers were carried out to investigate how Quality Management can be practised within organizations in order to promote sustainable co-worker health. These investigations took place in four organizations that had received awards. Three had been awarded for their excellence in leadership, work environment and co-workership, along with improved profitability; one for its successful implementation of quality programmes. The results are descriptions of methodologies, behaviours, values and organization structure used by the organizations to support sustainable health. These are exemplified with practical examples. The methodologies, behaviours, values, and organizational structure are considered possible for other organizations to adopt and all of them are already supported in the quality, management and leadership literature. Support from the health literature is also found for most of the behaviours, methodologies, values, and organizational structure. Surveys and focus groups interviews were carried out in five different organizations in order to find out what is of most importance when practising Quality Management in order to influence sustainable co-worker health. The results pointed to ‘Leadership Commitment’ as the most central of the values for achieving sustainable health among the co-workers. Furthermore, the values ‘Continuous Improvements’, ‘Participation of Everybody’ and ‘Customer Orientation’ were found to be related to sustainable health among the co-workers. The values ‘Leadership Commitment’ and the value ‘Participation of Everybody’ were then further elaborated to find aspects of importance for sustainable co-worker health. From the value ‘Leadership Commitment’ four aspects were extracted. These were labelled ‘Empathy’, ‘Presence and Communication’, ‘Integrity’, and ‘Continuity’. The results showed relations between the value ‘Leadership Commitment’ within Quality Management and sustainable health among the co-workers. Thus it is essential for leaders to work in accordance with that value to achieve results in the work towards sustainable co-worker health. The results indicate that this requires management and leadership that are characterized by the aspects above. The leaders have to: • Really understand the co-workers and their work situation. • Be present and available for co-workers and communicate with them. • Act as a role model, be fair and keep their promises. • Stay in their positions long enough to build up trust and confidence. The value ‘Participation of Everybody’ has also been shown to be related to sustainable health among the co-workers. This indicates that it is important to work in accordance with that value in the struggle to achieve sustainable health among the co-workers. The results imply that this value is characterized by the aspects ‘Development’, ‘Influence’ and ‘Being informed’. This could be done by: • Giving the co-workers opportunities to develop their skills and develop personally. • Letting the co-workers influence their work situation and taking suggestions and proposals from them seriously. • Having good communication within the whole organization. To manage this; the managers have to delegate more and empower the co-workers. These results were then further elaborated within another organization in order to develop a measurement approach that can clarify the extent to which the values, ‘Leadership Commitment’ and ‘Participation of Everybody’ permeate an organization. The developed measurement approach can be used to clarify the extent to which the organization is practising the health-promoting values within Quality Management and in what areas improvement is needed to increase co-worker health. The approach can also help the organization to detect those shortcomings within the management which are important for co-worker well-being. The developed measurement approach can be used to establish and enhance co-worker health by improving their well-being, satisfaction and motivation.
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| 4. |
- Bäckström, Ingela, 1963-
(författare)
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Quality Management for Sustainable Health : Methodologies, Values and Practices taken from Swedish Organizations
- 2006
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In many Western countries today, not least in Sweden, there are a lot of organizations that have great problems with sickness absence. The costs connected to the high rates of sickness absence have also risen to alarming levels. Healthy co-workers and healthy organizations are obvious goals for many leaders, but this is not always so easy to establish. Work practices and leadership that are beneficial to co-worker health are thus vital to identify. Studies have shown relationships between company-wide implementation of quality programs and improved co-worker satisfaction along with low co-worker turn over; in other words, co-worker health along with improved customer satisfaction and financial results. Despite the great problems concerning sickness absence, there are organizations that have been awarded prizes for excellence in leadership, internal partnership, working environment, and profitability. The overall purposes of the research described in this thesis are to examine and describe how management and leadership can establish sustainable health among the co-workers and examine how the leadership for sustainable health is related to Quality Management. The in-depth purpose is to examine which aspects within the values derived from the quality movement are those that primarily influence the co-workers’ perceived health. The results presented can be described in three parts and are results from four case studies carried out in five different organizations. Three of the organizations have received awards for establishing good working environment, good financial results, and low sick leaves among their co-workers; the fourth received an award for the successful implementation of quality programs. The first part consists of results from case studies in three different organizations and describes how organizations can work to achieve sustainable health among their co-workers, with practical examples. The results are methodologies, values and organizational structure, which it is considered possible for other organizations to adopt in their efforts to achieve good working conditions resulting in fewer sick leaves. The second part is an attempt to investigate if leadership for sustainable health is related to Quality Management. Methodologies, leadership values, organizational structure, and general values found in organizations which have achieved sustainable health are analyzed in the light of Deming’s 14 points, and a correlation is indicated. There is also correlation found between the TQM values and the co-workers’ perception of their health. The third part examines which of the aspects within the values grown from the quality movement are those that influence the co-workers perceived health. The results show significant correlation between the values and the co-workers’ perception of their health. Aspects found within the value “Top management commitment” were named; Empathy, Presence and Communication, Integrity, and Continuity. Within the value “Let everybody be committed” the aspects; Development, Influence and Being informed were found. These aspects are described in more detail and also in one model per value. The result implies that the TQM values; “Top management commitment”, “Improve continuously” “Let everybody be Committed” and “Focus on customers” are important for achieving healthy organizations and sustainable health among co-workers.
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| 5. |
- Bäckström, Josefin, 1977-
(författare)
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Family Members of Patients with Burns : Experiences of a Distressful Episode
- 2013
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- A severe burn is a trauma associated with long lasting consequences, not only for the survivor but also for the family. Although it is recognized that family members are central in providing social support for the patients, previous research has not focused extensively on this group. The aims of this thesis were to increase knowledge about psychological symptoms and health-related quality of life (HRQoL) in family members of patients with burns, as well as to explore their experiences of burn care and rehabilitation. The research questions were approached using quantitative and qualitative methods.The results showed that most family members demonstrate normal to mild levels of psychological symptoms, while one third demonstrate moderate to severe symptoms during care. The symptoms decreased over time and could be predicted to a certain degree by early symptoms.Further, family members’ report of HRQoL is similar to that of the general population. An improvement is seen over time and HRQoL could be predicted in part by earlier life events and psychological symptoms.Family members’ experiences were explored in an interview study. Qualitative content analysis revealed that the time in hospital is stressful, although there were experiences of a positive character. Family members might benefit from being cared for in a more individualized way. The communication between health care providers and the family members could be improved.Finally, a qualitative content analysis revealed that family members’ experiences and views concerning support is highly individual. There were experiences of sufficient support as well as lack of professional support. Treatment of family members should be modified according to personal circumstances, and it is important to actively include family members in the care process, both before and after discharge.In summary, being a family member of a burn survivor is a distressful experience, not only during care but in many cases also after discharge. The treatment of family members within burn care should be individualized. Some persons are more vulnerable than others and it might be possible to identify those in need of support while care is still ongoing.
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| 6. |
- Bäckström, Josefin, 1977-, et al.
(författare)
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Health-related quality of life in family members of patients with burns
- 2014
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Ingår i: Journal of Burn Care & Research. - 1559-047X .- 1559-0488. ; 35:3, s. 243-250
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Tidskriftsartikel (refereegranskat)abstract
- A severe burn not only affects the patients, but may also have a great impact on the lives of family members. It is known that family members of patients with burns experience psychological distress, but health-related quality of life (HRQoL) has not been studied in this group. The aim was to study predictors of HRQoL in family members of patients with burns. Forty-four family members of adult patients treated in a burn center, between 2000 and 2007, completed questionnaires during care, and at 3, 6, and 12 months after injury. HRQoL was assessed with the EuroQol 5D (EQ-5D), which consists of the dimensions: mobility, self-care, usual activities, pain, and anxiety/depression. The questionnaire generates an EQ-5D index and a visual analog scale (VAS) score. Overall, the EQ-5D index was similar to that of the general population. A slight improvement in HRQoL was found in the VAS scores and in the anxiety/depression dimension over time. In regression models, HRQoL was primarily predicted by earlier life events, symptoms of post-traumatic stress disorder, and HRQoL, assessed during the patients’ hospitalization. In summary, HRQoL assessed with VAS scores increased slightly during the first year postburn, and early screening for life events and psychological symptoms, and HRQoL might be useful in identifying family members in need of support.
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| 7. |
- Bäckström, Josefin, et al.
(författare)
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Prediction of psychological symptoms in family members of patients with burns 1 year after injury
- 2013
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Ingår i: Journal of Advanced Nursing. - : Wiley. - 0309-2402 .- 1365-2648. ; 69:2, s. 384-393
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Tidskriftsartikel (refereegranskat)abstract
- AimTo report a study of predictors of psychological symptoms in family members of patients with burns.BackgroundFamily members are important as a source of social support for patients undergoing prolonged rehabilitation. Little is known about psychological symptoms of family members of patients with burns, especially in the long term.DesignThe design of the study was prospective and longitudinal.MethodsForty-four family members of adult patients treated in a burn centre between 2000-2007 completed questionnaires during care and at 3, 6, and 12 months after injury. Psychological symptoms were assessed with the Hospital Anxiety and Depression Scale. Predictors for anxiety and depression were explored in regression analyses.ResultsThe mean scores indicated normal to mild symptoms in general. Moderate and severe symptom levels during care and at 12 months were demonstrated on the anxiety subscale by 15/44 and 5/39, respectively, and on the depression subscale by 5/44 and 0/39 of the family members, respectively. In the final regression models, the primary predictor was psychological symptoms at the previous assessment. Other predictors were previous life events, age, and the coping strategy avoidance.ConclusionFamily members of patients with burns demonstrate normal to mild levels of psychological symptoms that decrease over time. One-third show moderate to severe anxiety symptoms during care and may benefit from counselling. Previous symptoms predict later symptoms, indicating that screening with a validated instrument is useful. The results provide guidance for nurses in assessing and planning adequate interventions for family members.
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| 8. |
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Codex and Code : Aestethcis, Language and Politics in an Age of Digital Media, NORLIT 2009, Stockholm, August 6-9, 2009
- 2010
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- The conference Codex and Code: Aesthetics, Language and Politics in an Age of Digital Media (NorLit 2009)was held at the Royal Institute of Technology (KTH) in Stockholm, August 6–9, 2009. The conference was organized by the Nordic Association for Comparative Literature (NorLit); the Department of Culture and Communication, Linköping University; the School of Computer Science and Communication, Royal Institute of Technology (KTH); the Department of Comparative Literature, Stockholm University; the Department of Culture and Communication, Södertörn University College; and the Department of Comparative Literature, Uppsala University. The aim of the conference was to develop the study of Comparative Literature through Nordic collaboration both in its own discipline and in Modern Language and Cultural studies. As the title for the conference suggests, the principal question for the conference was the challenge that the study of literature encounters in an age of digitalization and globalization. It was our aim to encourage discussion of how literary studies respond to the ongoing changes in media and technology, politics and economy. Many have argued that the Humanities currently are in a state of crisis. We believe that the discipline seldom has found itself in such an interesting and fruitful historical moment. Several of these questions have surfaced during earlier media system changes, in particular during Romanticism and Modernism, which provided the conference with an historical frame. The conference Codex and Code also addressed questions of authenticity and originality, identity and gender, literary genres and reading practices, media and materiality, culture and popular culture, language and history, world literature, work aesthetics, translations, and canon formation. The conference Codex and Code wanted to stimulate interdisciplinary scholarly research of the literary in a broad sense. The conference was open to scholars in Comparative Literature and in Classical and Modern Languages, Aesthetics, Media and Communication studies, Film and Theatre studies, Philosophy and adjacent disciplines. The conference was organized around a number of thematic sessions in which researchers and scholars presented and discussed papers. The conference has received generous financial support from the Bank of Sweden Tercentenary Foundation, Magnus Bergwall foundation, Granholms foundation, Linköping University, School of Computer Science and Communication, Royal Institute of Technology, Svenska litteratursällskapet; the Swedish Academy, Swedish Science Council, and Vitterhetsakademien.
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| 9. |
-
Codex and Code: Aestethcis, Language and Politics in an Age of Digital Media : NORLIT 2009, Stockholm, August 6-9, 2009
- 2010
-
Proceedings (redaktörskap) (refereegranskat)abstract
- The aim of the conference was to develop the study of Comparative Literature through Nordic collaboration both in its own discipline and in Modern Language and Cultural studies. As the title for the conference suggests, the principal question for the conference was the challenge that the study of literature encounters in an age of digitalization and globalization. It was our aim to encourage discussion of how literary studies respond to the ongoing changes in media and technology, politics and economy. Many have argued that the Humanities currently are in a state of crisis. We believe that the discipline seldom has found itself in such an interesting and fruitful historical moment. Several of these questions have surfaced duringearlier media system changes, in particular during Romanticism and Modernism, which provided the conference with an historical frame. The conference Codex and Code also addressed questions of authenticity and originality, identity and gender, literary genres and reading practices, media and materiality, culture and popular culture, language and history, world literature, work aesthetics, translations, and canon formation.
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| 10. |
- Kahn, Robin, et al.
(författare)
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Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms
- 2022
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Ingår i: Acta Paediatrica, International Journal of Paediatrics. - : Wiley. - 0803-5253 .- 1651-2227. ; 111:2, s. 354-62
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Our aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. Methods: This national, population-based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS-C. The outcomes 2 and 8weeks after diagnosis are presented, and follow-up protocols are suggested. Results: We identified 152 cases, and 133 (87%) participated. When followed up 2weeks after MIS-C was diagnosed, 43% of the 119 patients had abnormal results, including complete blood cell counts, platelet counts, albumin levels, electrocardiograms and echocardiograms. After 8weeks, 36% of 89 had an abnormal patient history, but clinical findings were uncommon. Echocardiogram results were abnormal in 5% of 67, and the most common complaint was fatigue. Older children and those who received intensive care were more likely to report symptoms and have abnormal cardiac results. Conclusion: More than a third (36%) of the patients had persistent symptoms 8weeks after MIS-C, and 5% had abnormal echocardiograms. Older age and higher levels of initial care appeared to be risk factors. Structured follow-up visits are important after MIS-C.
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| 11. |
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| 12. |
- Lindahl, Göran, et al.
(författare)
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Stavanger : Innerstaden - Utvecklingshistoria och Utvecklingsmöjligheter
- 1972
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Rapport (populärvet., debatt m.m.)abstract
- Föreliggande arbete bör inte uppfattas som något slags generalplan eller dispositionsplan utan snarare som en presentation av ett synsätt, som konkretiserats på ett antal fritt valda områden. Framställningen har två tyngdpunkter. Stort intresse har ägnats det historiska perspektivet. Syftet har varit att besvara frågan: Varför ser Stavanger ut som det gör? Varför skiljer sig denna stad så mycket från jämförbara orter i Sverige? De svar som ges för över till bokens huvudtema, frågan hur den befintliga bebyggelsen skall användas i framtiden. Bakom ligger en grundsyn som uppfattar rivning och nybyggande som åtgärder i sista hand, underhåll, upprustning och ombyggnad som det normala, något som kan sträckas ut generation eftel" generation.
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| 13. |
- Löfgren, Magnus, 1979-, et al.
(författare)
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Progesterone withdrawal effects in the open field test can be predicted by elevated plus maze performance
- 2006
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Ingår i: Hormones and Behavior. - : Elsevier BV. - 0018-506X .- 1095-6867. ; 50:2, s. 208-215
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Tidskriftsartikel (refereegranskat)abstract
- Allopregnanolone (3alpha-hydroxy-5alpha-pregnane-20-one) is a ring-A-reduced metabolite of progesterone, which is naturally produced during the luteal phase of the menstrual cycle, during pregnancy and by stressful events. The steroid hormone inhibits neural functions through increased chloride ion flux through the GABAA receptor. The effects and subsequent withdrawal symptoms are similar to those caused by alcohol, benzodiazepines and barbiturates. This study examined the withdrawal effects of progesterone with regards to the influence of individual baseline exploration and risk taking. Rats were tested on the elevated plus maze (EPM) before hormonal treatment, in order to evaluate differences in risk taking and exploration of open and elevated areas. Treatment consisted of ten consecutive once a day progesterone or vehicle s.c. injections. On the last day of treatment, estradiol was injected in addition to progesterone, followed by a 24-h withdrawal before testing in the open field test (OF). Progesterone-treated rats showed a withdrawal effect of open area avoidance in the OF. The vehicle-treated control rats showed strong correlations between the EPM and OF parameters. This relationship was not found for the progesterone group at withdrawal. Rats with greater numbers of open arm entrance in the EPM pretest showed an increased sensitivity to progesterone withdrawal (PWD) compared to rats with low exploration and risk taking. The results indicate that the effects of PWD relate to individual exploration and risk taking. Furthermore, the possible analogy of PWD and PMS/PMDD in relation to individual traits is discussed.
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| 14. |
- Löfgren, Magnus, 1979-, et al.
(författare)
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Withdrawal effects from progesterone and estradiol relate to individual risk-taking and explorative behavior in female rats
- 2009
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Ingår i: Physiology and Behavior. - : Elsevier BV. - 0031-9384 .- 1873-507X. ; 96:1, s. 91-97
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Tidskriftsartikel (refereegranskat)abstract
- Withdrawal from progesterone and estradiol has been used as an animal model of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). In the clinical population individual sensitivity to sex steroid hormones, personality and heredity influence PMS/PMDD. Understanding the phenotypic risk factors of PMS/PMDD and drug development requires an animal model which incorporates individual steroid sensitivity. The main objective of this study was to investigate whether the individual trait of risk-taking and exploration influence the severity of PEWD in female rats. Thirty-two female Wistar rats in their diestrus phase were tested in the open field (OF) and divided into high responders (HR) and low responders (LR). Injections were given i.p. twice daily for 6 days, either 5 mg/kg progesterone combined with 10 mu g/kg 17 beta-estradiol, or vehicle (sesame oil). After a 24-hour withdrawal the animals were tested in the elevated plus maze (EPM). Blood samples for CORT analysis were collected after both behavioral tests. The HR rats withdrawn from progesterone and estradiol, spent less time on the EPM open arms and had lower CORT levels than the HR controls. The LR group showed no differences in EPM behavior and CORT levels during PEWD. The controls showed a stable trait of risk-taking and exploration. indicated by behavioral and CORT level correlations between the OF and EPM tests. These findings show that female rats with the trait of risk-taking and explorative behavior (HR) are more affected by PEWD.
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| 15. |
- Mjörndal, Tom, et al.
(författare)
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Adverse drug reactions as a cause for admissions to a department of internal medicine.
- 2002
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Ingår i: Pharmacoepidemiology and Drug Safety. - : Wiley. - 1053-8569 .- 1099-1557. ; 11:1, s. 65-72
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To assess the occurrence and pattern of adverse drug reactions as a cause for acute hospital admission.METHODS: In 681 randomly selected patients, acutely admitted to a clinic of internal medicine at a Swedish university hospital, information was collected from their medical records about current symptoms and use of drugs, previous diseases and the results of medical investigations and tests. In addition, a standardized interview according to a questionnaire was carried out. A group of experts in clinical pharmacology assessed the data obtained from the patients' case records and the results of the interviews, and then, according to WHO criteria, judged the probability that an adverse drug reaction could have caused or contributed to the actual admission to hospital.RESULTS: Out of the 681 cases included, 94 (13.8%) had symptoms and signs that were judged as drug-related and that had caused or contributed to the admission. Eighty-two patients (12.0%) had altogether 99 symptoms that were classified as adverse drug reactions. Of these, 91% were type A reactions. The relationship between the medication and the reaction was judged certain in eight, probable in 17, and possible in 74 cases. The most common adverse drug reactions were cardiovascular (36.3%). Twelve patients (1.8%) had symptoms indicating intoxications.CONCLUSIONS: The prevalence of drug-related problems causing or contributing to admission to a clinic of internal medicine is high and is dominated by type A reactions, i.e. reactions in principle predictable and preventable. This implies a possibility to increase drug safety by preventive measures.
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| 16. |
- Nilsson, Johanna, 1993, et al.
(författare)
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Cerebrospinal fluid biomarkers of synaptic dysfunction are altered in Parkinson's disease and related disorders
- 2023
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Ingår i: Movement Disorders. - : John Wiley & Sons. - 0885-3185 .- 1531-8257. ; 38:2, s. 267-277
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Tidskriftsartikel (refereegranskat)abstract
- Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects.Objective: To explore candidate biomarkers of synaptic dysfunction in Parkinson's disease (PD) and related disorders.Methods: Mass spectrometry was used to quantify 15 synaptic proteins in two clinical cerebrospinal fluid (CSF) cohorts, including PD (n1 = 51, n2 = 101), corticobasal degeneration (CBD) (n1 = 11, n2 = 3), progressive supranuclear palsy (PSP) (n1 = 22, n2 = 21), multiple system atrophy (MSA) (n1 = 31, n2 = 26), and healthy control (HC) (n1 = 48, n2 = 30) participants, as well as Alzheimer's disease (AD) (n2 = 23) patients in the second cohort.Results: Across both cohorts, lower levels of the neuronal pentraxins (NPTX; 1, 2, and receptor) were found in PD, MSA, and PSP, compared with HC. In MSA and PSP, lower neurogranin, AP2B1, and complexin-2 levels compared with HC were observed. In AD, levels of 14-3-3 zeta/delta, beta- and gamma-synuclein were higher compared with the parkinsonian disorders. Lower pentraxin levels in PD correlated with Mini-Mental State Exam scores and specific cognitive deficits (NPTX2; rho = 0.25–0.32, P < 0.05) and reduced dopaminergic pre-synaptic integrity as measured by DaTSCAN (NPTX2; rho = 0.29, P = 0.023). Additionally, lower levels were associated with the progression of postural imbalance and gait difficulty symptoms (All NPTX; β-estimate = −0.025 to −0.038, P < 0.05) and cognitive decline (NPTX2; β-estimate = 0.32, P = 0.021).Conclusions: These novel findings show different alterations of synaptic proteins in parkinsonian disorders compared with AD and HC. The neuronal pentraxins may serve as prognostic CSF biomarkers for both cognitive and motor symptom progression in PD.
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| 17. |
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NORLIT 2009, Codex and Code: Aestethcis, Language and Politics in an Age of Digital Media : Stockholm, August 6-9, 2009
- 2010
-
Proceedings (redaktörskap) (refereegranskat)abstract
- The aim of the conference was to develop the study of Comparative Literature through Nordic collaboration both in its own discipline and in Modern Language and Cultural studies. As the title for the conference suggests, the principal question for the conference was the challenge that the study of literature encounters in an age of digitalization and globalization. It was our aim to encourage discussion of how literary studies respond to the ongoing changes in media and technology, politics and economy. Many have argued that the Humanities currently are in a state of crisis. We believe that the discipline seldom has found itself in such an interesting and fruitful historical moment. Several of these questions have surfaced duringearlier media system changes, in particular during Romanticism and Modernism, which provided the conference with an historical frame. The conference Codex and Code also addressed questions of authenticity and originality, identity and gender, literary genres and reading practices, media and materiality, culture and popular culture, language and history, world literature, work aesthetics, translations, and canon formation.
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| 18. |
- Ragulis, Paulius, et al.
(författare)
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Shielding Effectiveness of Modern Energy-Saving Glasses and Windows
- 2017
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Ingår i: IEEE Transactions on Antennas and Propagation. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-926X .- 1558-2221. ; 65:8, s. 4250-4258
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Tidskriftsartikel (refereegranskat)abstract
- Thin metal coatings on glass are widely used in modern windows to improve their thermal properties. However, while there are some available papers on the properties of microwave propagation through commercial metallized windows glass below 6 GHz there seems to be a lack of papers regarding metallized multi-glazed windows at higher frequencies. Such data are of the great importance when designing modern microwave communication systems working in urban environments. In this paper, the shielding effectiveness of modern energy-saving glasses and windows were investigated at microwave frequencies from 1 GHz to 20 GHz. Wide measurement range together with proposed fast calculation procedure based on the matrix multiplication method, allowed us to elucidate the reasons responsible for the extremes in dependencies of shielding effectiveness on frequency. It was also shown that by comparing measured and calculated results, the conductivity of the thin metallic layer used in modern energy-saving windows can be determined. During the study, we found that attenuation of microwave radiation passing through modern windows can be as high as 60 dB.
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| 19. |
- Takahashi, Kayo, 1977-
(författare)
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Imaging brain aromatase by using PET : A way to study anabolic steroid abuse
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Aromatase is an enzyme that facilitates the conversion of androgens to estrogens and may play a role in mood and mental status. The main theme of this thesis is the imaging of brain aromatase by use of the PET technique. The PET tracer for aromatase, 11C-labeled vorozole (VOZ) was developed and evaluated by with in vitro and in vivo methods. In vitro experiments using rat brain showed that VOZ was distributed in the medial amygdala, bed nucleus of the stria terminalis and medial preoptic area, regions of the brain known to be rich in aromatase and the KD value was determined to be 0.60 nM. The in vivo PET study in rhesus monkey brain revealed that VOZ penetrated the blood-brain barrier and accumulated in the amygdala and hypothalamus. Taken together, VOZ is a good PET tracer for in vivo aromatase imaging with high affinity and high sensitivity.This technique was applied to an investigation of brain aromatase under the physiological conditions simulating anabolic-androgenic steroid abuse. A significant increase in VOZ binding by anabolic-androgenic steroids was observed in the bed nucleus of stria terminalis and medial preoptic area in the rat brain. In contrast, no significant change in binding was observed in the medial amygdala. These results indicate that the manner of regulation of aromatase expression might be different in the bed nucleus of stria terminalis and medial preoptic area compared with that in the medial amygdala. The aromatase expression was suggested to be regulated through androgen receptors, as indicated in a study with flutamide treatment. The increased aromatase expression was seen in neurons. The PET study with anabolic steroid-treated rhesus monkeys also showed increased VOZ binding in the hypothalamus but not in the amygdala. The alteration of density of aromatase binding in the hypothalamic area could explain some psychological features of anabolic-androgenic steroid abusers.Novel PET tracers for aromatase were developed and examined. The two newly synthesized 18F-labeled vorozole analogs, [18F]FVOZ and [18F]FVOO, displayed different characteristics. Both tracers showed similar binding pattern as VOZ; however, [18F]FVOO was metabolized very quickly, meaning that this tracer is not suitable as a PET tracer. On the other hand, [18F]FVOZ can be an appropriate PET tracer.The role of aromatase in the human brain has not been clarified yet. To approach this problem by in vivo methods, we have just started PET studies to explore aromatase expression in humans.
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| 20. |
- Ängskog, Per, 1964-, et al.
(författare)
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High Power Microwave Effects on Coated Window Panes
- 2015
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Ingår i: Asia Electromagnetics Conference (ASIAEM) 2015.
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Konferensbidrag (refereegranskat)abstract
- Today window panes are usually coated with at least one metal or metal oxide layer to prevent heat energy of the light spectrum from propagating to the other side. This has given problems regarding radio propagation through windows, which might be utilized as a part of a buildings IEMI protection. This paper reports the results from measurements of the shielding effectiveness of a selection of modern window panes before and after irradiation with high power electromagnetic waves. The shielding effectiveness measurements are made in a nested reverberation chamber covering the range 1 – 18 GHz; both before and after high power irradiation at 1.3 GHz. The results show that the shielding effectiveness of window panes may be severely impaired due to thermal stress effects on the coatings during the irradiation, depending of the type of coating.
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| 21. |
- Ängskog, Per, et al.
(författare)
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Measurement of Radio Signal Propagation through Window Panes and Energy Saving Windows
- 2015
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Ingår i: 2015 IEEE International Symposium on Electromagnetic Compatibility (EMC). - : IEEE conference proceedings. - 9781479966158 ; , s. 74-79
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Konferensbidrag (refereegranskat)abstract
- Glass windows have undergone an energy saving evolution over the past three, four decades, from single panes till today’s ultralow-emission windows. While the earliest energy saving windows were constructed as a sandwich of clear glass panes using the vacuum-flask principle, modern low-emission windows includes panes with coatings of metal and/or metal oxides. This coating has caused radio propagation problems for communication systems; something that may be utilized to protect a building from intentional electromagnetic interference (IEMI) attacks and to help protecting against information leakage. In this paper measurements of the shielding performance of different generations of windows and qualities of window panes are presented. The intention is to include the results in a guide-line for IEMI protection of critical infrastructures. Measurements are made using two complementary methods; in a nested reverberation chamber and in a semi-anechoic chamber, both over the range 1 – 18 GHz. The results show a clear generation dependency where the energy saving windows largely do not attenuate RF signals at all and low-emission windows offer shielding effectiveness values between 10 and 45 dB with potentially as much as around 60 dB in the upper half of the spectrum.
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| 22. |
- Ängskog, Per, 1964-, et al.
(författare)
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Shielding Effectiveness and HPM Vulnerability of Energy-Saving Windows and Window Panes
- 2019
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Ingår i: IEEE transactions on electromagnetic compatibility (Print). - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0018-9375 .- 1558-187X. ; 61:3, s. 870-877
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we report results from shielding effectiveness measurements on energy-saving windows and individual, coated window panes of different generations, as well as results from high-power microwave irradiation on single panes. Shielding effectiveness was measured with two complementary methods: first, with near isotropic irradiation in nested reverberation chambers, and the other with irradiation at normal incidence in a semianechoic chamber. The measurements show that the construction of the energy conserving windows has a clear impact on how well they attenuate radio frequency signals. The more modern the window or pane, the higher is the shielding effectiveness. The high-power irradiation on coated panes showed that depending on the type of coating, hotspots can build up causing the coating to crack and, hence, deteriorate the shielding effectiveness. These results may serve as guidance when reviewing high-altitude electromagnetic pulse (EMP), high-power microwave, or intentional electromagnetic interference protection of critical infrastructures, and provide assistance in the work with reduction of compromising emanations.
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| 23. |
- Ängskog, Per, et al.
(författare)
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Shielding Effectiveness of Energy Saving Windows and HPM Effects on Coated Window Panes Measurements Conducted 2014-2016-Results and Lessons Learned
- 2016
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Ingår i: PROCEEDINGS OF THE 2016 INTERNATIONAL SYMPOSIUM ON ELECTROMAGNETIC COMPATIBILITY - EMC EUROPE. - : IEEE conference proceedings. - 9781509014163 ; , s. 461-466, s. 461-466
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Konferensbidrag (refereegranskat)abstract
- The past few decades have shown a veritable explosion of new versions of energy-saving windows and coated window panes. In the wake of this, problems with radio communications into and from within buildings has arisen. However, this unexpected attenuation of radio signals may also be used to shield a facility from incoming intentional electromagnetic interference (IEMI). With the intention to investigate the shielding effectiveness (SE) of modern windows and window panes a two-year measurement campaign was launched mid-2014. Another, little investigated area is what happens to coated glass when irradiated by a high-power microwave (HPM) source. Shielding effectiveness has been measured for different types of energy saving windows and coated window panes both in a semi-anechoic chamber and in a reverberation chamber over the frequency range 1-18 GHz. The effects of HPM irradiation were studied by comparing SE measured before and after the pulsed 28 kV/m L-band irradiation. The main conclusion is that with the right choice of window the shielding effectiveness of a building can reach up 40-50 dB. In this paper we summarize these measurements and lessons learned from the measurement campaign.
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| 24. |
- Ängskog, Per, 1964-, et al.
(författare)
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Shielding Effectiveness Studies of Energy Saving Windows and Coated Window Panes - a Summary
- 2016
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Ingår i: Proceedings of the European Electromagnetics Symposium (EUROEM) 2016. - London : Institution of Engineering and Technology.
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Konferensbidrag (refereegranskat)abstract
- In recent decades, window panes and windows have undergone a virtual revolution with respect to energy saving. Along with this revolution a strong reduction of radio transmission capability through windows has followed. It has been observed that radio communication (e.g. mobile telephony) in newly built or renovated buildings has become increasingly difficult to accomplish due to the higher attenuation in these energy-saving windows. On the upside though, the increased attenuation can help in the protection against intentional electromagnetic interference (IEMI) and compromising emanations from activities inside the building.In this paper we summarize shielding effectiveness (SE) measurements conducted on window panes and window modules during 2014 and 2015 and give some conclusions drawn regarding do’s and don’ts when installing windows.
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| 25. |
- Ängskog, Per, 1964-, et al.
(författare)
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Shielding Effectiveness Study of Two Fabrics with Microwave Properties Before and After High Power Irradiation
- 2015
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Ingår i: Proceedings of the 2015 International Conference on Electromagnetics in Advanced Applications (ICEAA)ICEAA '15 - 17th Edition. - : IEEE conference proceedings. - 9781479978069 ; , s. 930-933
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Konferensbidrag (refereegranskat)abstract
- Over the past decade several applications forfabrics with electromagnetic properties have emerged, most ofthem relating to garments, including jackets with built-inantennas and workwear with increased radar visibility. Besidethese have surfaced two protective applications, namely toprotect transports of confidential equipment from discoveryand identification; and to protect sensitive apparatus fromdamage by high power electromagnetic irradiation e.g. in fieldoperations. In this paper results are presented frommeasurement of shielding effectiveness before and after highpower radiation for two types of fabrics under considerationfor the latter applications. Shielding effectivenessmeasurements have been conducted between 1 and 18 GHzwhile the high power irradiation
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| 26. |
- Ängskog, Per, 1964-, et al.
(författare)
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Skärmverkan och mikrovågseffekter på fönster och fönsterglas
- 2016
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Ingår i: Electronic Environment. - Göteborg : Just Rivista AB. ; -:3, s. 26-29
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Ett allt vanligare fenomen är att mobil telekommunikation inte fungerar i moderna/nybyggda hus. Detta kan härledas till de moderna energisparfönster som monteras in. Denna skärmverkan är inte bara ett problem utan kan också vändas till en fördel i de fall man vill skydda verksamhet från yttre elektromagnetiska störningar, till exempel avsiktlig elektromagnetisk störning (IEMI), samt i de fall då man vill undvika att röjande strålning (RÖS) från elektronisk utrustning läcker ut och kan avlyssnas.Här kommer vi presentera resultaten från mätningar av skärmverkan hos dels fönster av olika generation och dels enskilda fönsterglas med olika funktion som används för att bygga upp dessa fönster. Dessutom presenteras resultat från mätningar av hur skärmverkan påverkas vid bestrålning med högeffekts mikrovågsstrålning (HPM).
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