| 1. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
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| 3. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 4. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 9. |
- Bratt, H.I., et al.
(författare)
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Företagens syn på programvaror förändras : Ökade krav på snabb lönsamhet - Tema: Välja programvara
- 1992
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Ingår i: Diagonalen, nr 2, 1992, sid. 2-5. - Stockholm : Diab Data.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Konsten att köpa programvara är egentligen konsten att välja en bra leverantör. I grunden handlar det om sunt bondförnuft. Och det kan behövas, programvara är den klart viktigaste delen i en datorinvestering.Diagonalen lät tre erfarna herrar samtala om saken vid det runda bordet. Vi ställde några frågor och lyssnade på många kloka ord. De tre är: Anders G. Nilsson, ekonomie doktor vid Handelshögskolan i Stockholm. Hans Wärneryd, Svenska Branschsystem AB i Göteborg. Hans Iwan Bratt, VD för LKD, informatikföretagens organisation med huvudkontor i Danderyd.Det gäller att se klokt och pragmatiskt på programköpet, är deras budskap. Eftersom det gäller ny teknik på en svåröverskådlig marknad där det ständigt sker stora förändringar känner man sig inte lika säker som till exempel när man köper bil. Men i grunden är det samma sak. Man frågar sig inte vad bränslepumpen kan ha för kapacitet, man frågor sig om bilen är bra att skjutsa ungarna till dagis i
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| 13. |
- Martschin, C, et al.
(författare)
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[Strong increase of gonorrhea]
- 2010
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Ingår i: Lakartidningen. - 0023-7205. ; 107:6, s. 336-7
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Tidskriftsartikel (refereegranskat)
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| 14. |
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| 15. |
- Neogi, U., et al.
(författare)
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Recent increased identification and transmission of HIV-1 unique recombinant forms in Sweden
- 2017
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7
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Tidskriftsartikel (refereegranskat)abstract
- A temporal increase in non-B subtypes has earlier been described in Sweden by us and we hypothesized that this increased viral heterogeneity may become a hotspot for the development of more complex and unique recombinant forms (URFs) if the epidemics converge. In the present study, we performed subtyping using four automated tools and phylogenetic analysis by RAxML of pol gene sequences (n = 5246) and HIV-1 near full-length genome (HIV-NFLG) sequences (n = 104). A CD4(+) T-cell decline trajectory algorithm was used to estimate time of HIV infection. Transmission clusters were identified using the family-joining method. The analysis of HIV-NFLG and pol gene described 10.6% (11/104) and 2.6% (137/5246) of the strains as URFs, respectively. An increasing trend of URFs was observed in recent years by both approaches (p = 0 ; 0082; p < 0 . 0001). Transmission cluster analysis using the pol gene of all URFs identified 14 clusters with two to eight sequences. Larger transmission clusters of URFs (BF1 and 01B) were observed among MSM who mostly were sero-diagnosed in recent time. Understanding the increased appearance and transmission of URFs in recent years could have importance for public health interventions and the use of HIV-NFLG would provide better statistical support for such assessments.
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| 34. |
- Bratt, Ola, 1963, et al.
(författare)
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Prostate cancer in kidney transplant recipients - a nationwide register study
- 2020
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Ingår i: Bju International. - : Wiley. - 1464-4096 .- 1464-410X. ; 125:5, s. 679-685
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Tidskriftsartikel (refereegranskat)abstract
- Objective To investigate whether post-transplantation immunosuppression negatively affects prostate cancer outcomes in male kidney transplant recipients. Patients and Methods We used the Swedish Renal Register and the National Prostate Cancer Register to identify all kidney transplantation recipients diagnosed with prostate cancer in Sweden 1998-2016. After linking these registers with Prostate Cancer Database Sweden (PCBaSe), a case-control study was designed to compare time period and risk category-specific probabilities of a prostate cancer diagnosis amongst kidney transplantation recipients versus the male general population. The registers did not include information about the specific immunosuppression agent used in all transplantation recipients. Data from PCBaSe were used to compare prostate cancer characteristics at diagnosis and survival for patients with prostate cancer with versus without a kidney transplant. Propensity score matching, Cox regression analysis and Fisher's exact test were used and 95% confidence intervals (CIs) calculated. Results Almost half of the 133 kidney transplantation recipients were transplanted before the mid-1990s, when PSA testing became common. The transplant recipients were not more likely than age-matched control men to be diagnosed with any (odds ratio [OR] 0.84, 95% CI 0.70-0.99) or high-risk or metastatic prostate cancer (OR 0.84, 95% CI 0.62-1.13). None of the ORs for the different categories of prostate cancer increased with time since transplantation. Cancer characteristics at the time of diagnosis and cancer-specific survival were similar amongst transplant recipients and the control group of 665 men diagnosed with prostate cancer without a kidney transplant. Conclusions This Swedish nationwide, register-based study gave no indication that immunosuppression after kidney transplantation increases the risk of prostate cancer or adversely affects prostate cancer outcomes. The study suggests that men with untreated low-grade prostate cancer can be accepted for transplantation.
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| 39. |
- Casper, C, et al.
(författare)
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Coreceptor usage of primary HIV type 1 isolates obtained from different lymph node subsets
- 2005
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Ingår i: AIDS Research and Human Retroviruses. - : Mary Ann Liebert Inc. - 1931-8405 .- 0889-2229. ; 21:12, s. 1003-1010
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Tidskriftsartikel (refereegranskat)abstract
- Biological characteristics of virus quantitatively rescued from different cell types present in lymph nodes of HIV-1-infected individuals in various stages of their disease were determined, not including patients with AIDS defining illness. Viruses were obtained by cocultivation with donor monocyte-derived macrophages and T-lymphocytes and their biological phenotype compared to viruses obtained from the peripheral blood mononuclear cells of the same patient. The biological phenotype was determined on established cell lines (U937-2, CEM, and MT-2) and on the U87.CD4 coreceptor indicator cell lines and variable region 3 (V3) of the envelope was subjected to direct sequencing. All isolates obtained from lymph node subsets used CCR5 as coreceptor. Furthermore, these viruses were also sensitive to inhibition by beta-chemokines as analyzed for viruses of one patient. All 12 V3 regions showed a unique sequence indicating compartmentalization within each patient. The biological phenotype of CCR5-dependent (R5) HIV-1 isolates obtained from PBMC resembles the phenotype of viruses isolated from different lymph node cell subsets.
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| 40. |
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| 41. |
- Edlund, M, et al.
(författare)
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The spread of Mycoplasma genitalium among men who have sex with men
- 2012
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Ingår i: International journal of STD & AIDS. - : SAGE Publications. - 1758-1052 .- 0956-4624. ; 23:6, s. 455-456
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Tidskriftsartikel (refereegranskat)abstract
- We report two instances of urethral–to–rectal transmission of Mycoplasma genitalium (MG) in men who have sex with men (MSM) couples. Such clear epidemiological correlation has to our knowledge not been published before. The urethral infections led to clinical symptoms, but the rectal infections did not. The rectum might serve as a reservoir for MG in MSM, but there is also some evidence from the literature that MG can cause proctitis. Our finding raises important questions about the role of MG as a pathogen among MSM. Any correlation with HIV transmission risk is currently unknown and needs further research.
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| 42. |
- Ericson, Mats O, et al.
(författare)
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Load moments about the hip and knee joints during ergometer cycling.
- 1986
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Ingår i: Scandinavian Journal of Rehabilitation Medicine. - 0036-5505 .- 1940-2228. ; 18:4, s. 165-72
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to calculate the magnitudes of moments of force acting about the bilateral hip and knee joint axes during ergometer cycling. Six healthy subjects pedalled a weight-braked bicycle ergometer at different workloads, pedalling rates, saddle heights and pedal foot position. During cycling at 120 Watts, 60 revolutions per minute with mid-saddle height and anterior pedal foot position, the mean peak flexing and extending hip load moments were 34.3 and 8.9 Nm, respectively. Mean peak flexing knee load moments was 28.8 Nm and extending moment was 11.9 Nm. Hip load moments were significantly increased by increasing the ergometer workload or pedalling rate. For knee load moments, workload was the most important factor. The flexing knee load moment did not change with changes in pedalling rate. Different saddle heights or pedal food positions had a slight but not always statistically significant influence on the hip and knee joint loads. The maximum hip and knee joint load moments induced during cycling were small compared with those obtained during other exercises or normal activities such as level walking, stair climbing, and lifting.
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| 43. |
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| 44. |
- Esbjornsson, J., et al.
(författare)
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HIV-1 transmission between MSM and heterosexuals, and increasing proportions of circulating recombinant forms in the Nordic Countries
- 2016
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Ingår i: Virus Evolution. - : Oxford University Press (OUP). - 2057-1577. ; 2:1
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Tidskriftsartikel (refereegranskat)abstract
- Increased knowledge about HIV-1 transmission dynamics in different transmission groups and geographical regions is fundamental for assessing and designing prevention efforts against HIV-1 spread. Since the first reported cases of HIV infection during the early 1980s, the HIV-1 epidemic in the Nordic countries has been dominated by HIV-1 subtype B and MSM transmission. HIV-1 pol sequences and clinical data of 51 per cent of all newly diagnosed HIV-1 infections in Sweden, Denmark, and Finland in the period 2000-2012 (N = 3,802) were analysed together with a large reference sequence dataset (N = 4,537) by trend analysis and phylogenetics. Analysis of the eight dominating subtypes and CRFs in the Nordic countries (A, B, C, D, G, CRF01_AE, CRF02_AG, and CRF06_cpx) showed that the subtype B proportion decreased while the CRF proportion increased over the study period. A majority (57 per cent) of the Nordic sequences formed transmission clusters, with evidence of mixing both geographically and between transmission groups. Detailed analyses showed multiple occasions of transmissions from MSM to heterosexuals and that active transmission clusters more often involved single than multiple Nordic countries. The strongest geographical link was between Denmark and Sweden. Finally, Denmark had a larger proportion of heterosexual domestic spread of HIV-1 subtype B (75 per cent) compared with Sweden (49 per cent) and Finland (57 per cent). We describe different HIV-1 transmission patterns between countries and transmission groups in a large geographical region. Our results may have implications for public health interventions in targeting HIV-1 transmission networks and identifying where to introduce such interventions.
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