| 1. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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| 4. |
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| 5. |
- Athan, E., et al.
(författare)
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Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis
- 2017
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Ingår i: Clinical Microbiology and Infection. - : Elsevier BV. - 1198-743X .- 1469-0691. ; 23, s. 544-549
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Tidskriftsartikel (refereegranskat)abstract
- © 2017 European Society of Clinical Microbiology and Infectious Diseases Objectives Left-sided methicillin-susceptible Staphylococcus aureus (MSSA) endocarditis treated with cloxacillin has a poorer prognosis when the vancomycin minimum inhibitory concentration (MIC) is ≥1.5 mg/L. We aimed to validate this using the International Collaboration on Endocarditis cohort and to analyse whether specific genetic characteristics were associated with a high vancomycin MIC (≥1.5 mg/L) phenotype. Methods All patients with left-sided MSSA infective endocarditis treated with antistaphylococcal β-lactam antibiotics between 2000 and 2006 with available isolates were included. Vancomycin MIC was determined by Etest as either high (≥1.5 mg/L) or low (<1.5 mg/L). Isolates underwent spa typing to infer clonal complexes and multiplex PCR for identifying virulence genes. Univariate analysis was performed to evaluate the association between in-hospital and 1-year mortality, and vancomycin MIC phenotype. Results Sixty-two cases met the inclusion criteria. Vancomycin MIC was low in 28 cases (45%) and high in 34 cases (55%). No significant differences in patient demographic data or characteristics of infection were observed between patients with infective endocarditis due to high and low vancomycin MIC isolates. Isolates with high and low vancomycin MIC had similar distributions of virulence genes and clonal lineages. In-hospital and 1-year mortality did not differ significantly between the two groups (32% (9/28) vs. 27% (9/34), p 0.780; and 43% (12/28) vs. 29% (10/34), p 0.298, for low and high vancomycin MIC respectively). Conclusions In this international cohort of patients with left-sided MSSA endocarditis treated with antistaphylococcal β-lactams, vancomycin MIC phenotype was not associated with patient demographics, clinical outcome or virulence gene repertoire.
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| 6. |
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| 7. |
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| 8. |
- Heshmati, Almas, et al.
(författare)
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Introduction to and summary of the contributions
- 2012
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Ingår i: Perspectives on Kurdistan's economy and society in transition. - New York : Nova Science Publishers, Inc.. - 9781622579341 ; , s. 1-6
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 9. |
- Heshmati, Almas, et al.
(författare)
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Preface
- 2012
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Ingår i: Perspectives on Kurdistan's economy and society in transition. - New York : Nova Science Publishers, Inc.. - 9781622579341 ; , s. ix-x
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 10. |
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| 11. |
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Perspectives on Kurdistan’s economy and society in transition
- 2012
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- The First World Kurdish Congress was held in October 2011 at Rotterdam with the theme of researching science and culture towards increased progress in Kurdistan. The papers presented focused on various important aspects of health, education, economy, culture and political science in Kurdistan. The objective was to create a network of academicians to exchange and develop knowledge on how to further enhance the progress within the Kurdish society. This book is a collection of 20 studies presented at the Congress. The presentation topics are diverse, covering several areas pertinent to the current Kurdish situation. The studies are divided into eight areas including: human rights and freedom; greater Kurdistan, education and nation building; diaspora; politics and international relations; corruption; health care and trauma; and economy, business and science and technology. ©2012 by Nova Science Publishers, Inc. All rights reserved.
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| 12. |
- Qadir, Harem O., et al.
(författare)
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Potential field survey of subsurface structures of the NW segment of the Zagros Fold-Thrust Belt, Kurdistan Region
- 2023
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Ingår i: Geophysical Prospecting. - : John Wiley & Sons. - 0016-8025 .- 1365-2478. ; 71:8, s. 1673-1690
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Tidskriftsartikel (refereegranskat)abstract
- This study reports results of gravity and magnetic surveys conducted for the first time in the western segment of the Zagros Fold-and-Thrust Belt in the Kurdistan Region. This study attempts to delineate deep structures in an area, which has not been surveyed before. CG-5 Autograv gravimeter and G-857 portable proton-precession magnetometer were used to acquire gravity and magnetic data from 750 stations along over eleven traverses across and parallel to the Zagros trend (NW-SE). Six of these traverses are parallel to the Zagros trend, whereas the others are perpendicular to the trend of the other traverses and can be tied where they intersect. The total length of the traverses is about 1000 km. Tilt Angle of horizontal gradient method is used to detect regional gravity and magnetic lineaments. The mapped lineaments from regional gravity and magnetic surveys are divided into two categories: the NE-SW lineaments, which represent transversal faults in the study area, and the NW-SE lineaments, which represent the Zagros Thrust Faults, some of which may be linked to the inverted basement normal faults of Arabian passive margin (the NW-SE Najd Fault system). The results show that there is a relationship between the regional gravity and magnetic lineaments outlining the same deep geological features. The data presented here confirm the presence of regional longitudinal and transversal lineaments documented in other studies (e.g. Anah-Qalat Dizeh Fault, Surdash-Tikrit Fault, Sirwan Fault, Khanaqin Fault, Zagros Mountain Front Fault, Baranan Back Thrust Fault and High Zagros Reverse Fault) and outlines new lineaments not mapped before. Most of the detected regional lineaments in the current study coincide with the previously confirmed lineaments, which have played a significant role in the tectonic evolution of the Zagros Fold-and-Thrust Belt. As such, this study contributes to a better understanding of the subsurface structure of the Kurdistan segment of the Zagros Fold-and-Thrust Belt and probably the rest of the belt.
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| 13. |
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