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- Bahat, Gulistan, et al.
(författare)
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Paving the way for applying GLIM criteria in clinical practice and research : how to define mild to moderate and severe reduced muscle mass
- 2022
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Ingår i: European Geriatric Medicine. - : Springer Nature. - 1878-7649 .- 1878-7657. ; 13:3, s. 611-614
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Tidskriftsartikel (refereegranskat)abstract
- Key summary pointsAim To report grade 1 and grade 2 reduced muscle mass cut-offs for skeletal muscle mass (SMM) adjusted by body mass index (BMI) to increase the applicability of the GLIM criteria. Findings Grade 1 vs. grade 2 low muscle mass (LMM) thresholds were 1.189 and 0.954 kg/BMI vs. 1.049 and 0.823 kg/BMI in males and females, respectively. Message While validation studies are needed to evaluate their predictive ability, our approach presented here seems applicable and the cut-off values acceptable for use until population-specific values in different populations or global generic cut-offs are identified. Purpose Among approaches to adjust skeletal muscle mass (SMM) for body size, adjustment for body mass index (BMI) correlated better with functional measures. To enhance applicability of GLIM criteria, we report grade 1 and grade 2 reduced muscle mass cut-offs for SMM adjusted by BMI. Methods 301 young, healthy adults involving students, patient relatives and staff working in the university hospital were included. SMM was estimated by bio-impedance analysis (BIA). SMM index (BMI) [SMMI(BMI)] was calculated as SMM/BMI. Grade 1 low muscle mass (LMM) was defined as "mean young SMMI(BMI)-one standard deviation" and grade 2 LMM as "mean young SMMI(BMI)-two standard deviations". Results Mean age was 26.5 +/- 4.6 (62.1% male). Grade 1 vs grade 2 LMM thresholds were 1.189 and 0.954 kg/BMI vs 1.049 and 0.823 kg/BMI in males and females, respectively. Conclusion This is the first report identifying stage 1 and stage 2 LMM thresholds for SMMI adjusted by BMI. Studies are needed to evaluate their predictive validity.
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| 2. |
- Cruz-Jentoft, Alfonso J., et al.
(författare)
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Sarcopenia : revised European consensus on definition and diagnosis
- 2019
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Ingår i: Age and Ageing. - : OXFORD UNIV PRESS. - 0002-0729 .- 1468-2834. ; 48:1, s. 16-31
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Tidskriftsartikel (refereegranskat)abstract
- Background: In 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings.Objectives: To increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia.Recommendations: Sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia.Conclusions; EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.
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| 3. |
- Soulis, George, et al.
(författare)
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Geriatric care in European countries where geriatric medicine is still emerging
- 2020
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Ingår i: European Geriatric Medicine. - : Springer Science and Business Media LLC. - 1878-7649 .- 1878-7657.
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: Practicing geriatric medicine is a challenging task since it involves working together with other medical doctors while coordinating a multidisciplinary team. Global Europe Initiative (GEI) group within the European Geriatric Medicine Society gathers geriatricians from different regions where geriatrics is underrepresented or still developing to promote initiatives for the advancement of geriatric medicine within these countries. Methods: Here we present a first effort to describe several aspects that affect practicing geriatric medicine in five different countries: Greece, Portugal, Russia, Turkey, and Tunisia. Results: We can notice discrepancies between countries concerning all dimensions of geriatrics (recognition, training, educational and professional standards, academic representation, working context). Conclusions: These differences correspond to the specificities of each country and set the frame where geriatric medicine is going to be developed across Europe. EuGMS with GEI group can provide useful support.
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