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| 2. |
- Hensiek, A E, et al.
(författare)
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Familial effects on the clinical course of multiple sclerosis.
- 2007
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Ingår i: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 68:5, s. 376-83
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Familial factors influence susceptibility to multiple sclerosis (MS) but it is unknown whether there are additional effects on the natural history of the disease. METHOD: We evaluated 1,083 families with > or =2 first-degree relatives with MS for concordance of age at onset, clinical course, and disease severity and investigated transmission patterns of these clinical features in affected parent-child pairs. RESULTS: There is concordance for age at onset for all families (correlation coefficient 0.14; p < 0.001), as well as for affected siblings (correlation coefficient 0.15; p < 0.001), and affected parent-child pairs (correlation coefficient 0.12; p = 0.03) when each is evaluated separately. Concordance for year of onset is present among affected siblings (correlation coefficient 0.18; p < 0.001) but not the parent-child group (correlation coefficient 0.08; p = 0.15). The clinical course is similar between siblings (kappa 0.12; p < 0.001) but not affected parents and their children (kappa -0.04; p = 0.09). This influence on the natural history is present in all clinical subgroups of relapsing-remitting, and primary and secondary progressive MS, reflecting a familial effect on episodic and progressive phases of the disease. There is no concordance for disease severity within any of the considered family groups (correlation coefficients: all families analyzed together, 0.02, p = 0.53; affected sibling group, 0.02, p = 0.61; affected parent-child group, 0.02, p = 0.69). Furthermore, there are no apparent transmission patterns of any of the investigated clinical features in affected parent-child pairs and no evidence for anticipation or effects of genetic loading. CONCLUSION: Familial factors do not significantly affect eventual disease severity. However, they increase the probability of a progressive clinical course, either from onset or after a phase of relapsing remitting disease. The familial effect is more likely to reflect genetic than environmental conditions. The results are relevant for counseling patients and have implications for the design of studies seeking to identify factors that influence the natural history of the disease.
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| 3. |
- Bencsik, G., et al.
(författare)
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Conducting polymer based multifunctional composite electrodes
- 2009
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Ingår i: Reaction Kinetics and Catalysis Letters. - : Springer. - 0133-1736 .- 1588-2837. ; 96, s. 421-428
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we report a novel pattern of composite electrocatalysts. PPy/iron-oxalate films exhibit photo-electrochemical activity. The PPy/B12 composite electrode on stainless steal (SS) support shows high catalytic activity in the electrochemical reduction of methylviologen. Thin polymer layers filled with magnetite particles can be applicable in magneto-selective electrochemical reactions.In this paper, we report a novel pattern of composite electrocatalysts. PPy/iron-oxalate films exhibit photo-electrochemical activity. The PPy/B12 composite electrode on stainless steal (SS) support shows high catalytic activity in the electrochemical reduction of methylviologen. Thin polymer layers filled with magnetite particles can be applicable in magneto-selective electrochemical reactions.
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| 4. |
- Endrodi, Balazs, et al.
(författare)
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Continuous-flow electroreduction of carbon dioxide
- 2017
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Ingår i: Progress in Energy and Combustion Science. - : Elsevier. - 0360-1285 .- 1873-216X. ; 62, s. 133-154
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Tidskriftsartikel (refereegranskat)abstract
- Solar fuel generation through electrochemical CO2 conversion offers an attractive avenue to store the energy of sunlight in the form of chemical bonds, with the simultaneous remediation of a greenhouse gas. While impressive progress has been achieved in developing novel nanostructured catalysts and understanding the mechanistic details of this process, limited knowledge has been gathered on continuous-flow electrochemical reactors for CO2 electroreduction. This is indeed surprising considering that this might be the only way to scale-up this fledgling technology for future industrial application. In this review article, we discuss the parameters that influence the performance of flow CO2 electrolyzers. This analysis spans the overall design of the electrochemical cell (microfluidic or membrane-based), the employed materials (catalyst, support, etc.), and the operational conditions (electrolyte, pressure, temperature, etc.). We highlight R&D avenues offering particularly promising development opportunities together with the intrinsic limitations of the different approaches. By collecting the most relevant characterization methods (together with the relevant descriptive parameters), we also present an assessment framework for benchmarking CO2electrolyzers. Finally, we give a brief outlook on photoelectrochemical reactors where solar energy input is directly utilized.
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| 5. |
- Endrodi, Balazs, et al.
(författare)
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Incorporation of cobalt-ferrite nanoparticles into a conducting polymer in aqueous micellar medium : Strategy to get photocatalytic composites
- 2014
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Ingår i: Acta Chimica Slovenica. - 1318-0207. ; 61, s. 376-381
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Tidskriftsartikel (refereegranskat)abstract
- In this study an easy strategy for conducting polymer based nanocomposite formation is presented through the deposition of cobalt-ferrite (CoFe 2O4) containing poly(3,4-ethylenedioxythiophene) (PEDOT) thin layers. The electrochemical polymerization has been performed galvanostatically in an aqueous micellar medium in the presence of the nanoparticlesand the surface active Triton X-100. The nanoparticles have been characterized by Transmission electron microscopy (TEM), the thin layers has been studied by applying Scanning electron microscopy (SEM), and X-ray diffraction (XRD), and the basic electrochemical properties have been also determined. Moreover, electrocatalytic activity of the composite was demonstrated in the electrooxidation reaction of dopamine (DA). The enhanced sensitivity - related to the cobalt-ferritecontent - and the experienced photocatalyitic activity are promising for future application.
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| 7. |
- Szabó, T., et al.
(författare)
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Charge stabilization by reaction center protein immobilized to carbon nanotubes functionalized by amine groups and poly(3-thiophene acetic acid) conducting polymer
- 2012
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Ingår i: Physica status solidi. B, Basic research. - : Wiley-VCH Verlagsgesellschaft. - 0370-1972 .- 1521-3951. ; 249:12, s. 2386-2389
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Tidskriftsartikel (refereegranskat)abstract
- A large number of studies have indicated recently that photosynthetic reaction center proteins (RC) bind successfully to nanostructures and their functional activity is largely retained. The major goal of current research is to find the most efficient systems and conditions for the photoelectric energy conversion and for the stability of this bio-nanocomposite. In our studies, we immobilized the RC protein on multiwalled carbon nanotubes (MWNT) through specific chemical binding to amine functional groups and through conducting polymer (poly(3-thiophene acetic acid), PTAA). Both structural (TEM, AFM) and functional (absorption change and conductivity) measurements has shown that RCs could be bound effectively to functionalized CNTs. The kinetics of the light induced absorption change indicated that RCs were still active in the composite and there was an interaction between the protein cofactors and the CNTs. The light generated photocurrent was measured in an electrochemical cell with transparent CNT electrode designed specially for this experiment.
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