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- Bouillon, Marc E., et al.
(författare)
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Synthesis of Anemoclemosides A and B, Two Saponins Isolated from Anemoclema glaucifolium
- 2020
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Ingår i: European Journal of Organic Chemistry. - : Wiley. - 1434-193X .- 1099-0690. ; 2020:48, s. 7470-7473
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Tidskriftsartikel (refereegranskat)abstract
- Steroidal and triterpenoid saponins are attractive for their wide-ranging pharmacological properties. The triterpenoid saponins Anemoclemoside A and B are root constituents of the Chinese folk medicinal plant Anemoclema glaucifolium (Ranunculaceae). Both compounds feature an unusual cyclic acetal linkage to the carbohydrate l-arabinose in its open chain form rather than the typical glycosidic bond present in normal saponins. The straightforward and scalable syntheses of both saponins starting from l-arabinose as well as l-lyxose and l-rhamnose are described.
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