| 1. |
- Blomqvist, Maria K., 1975, et al.
(author)
-
High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS
- 2017
-
In: Journal of Lipid Research. - 0022-2275. ; 58:7, s. 1482-1489
-
Journal article (peer-reviewed)abstract
- Sulfatides (STs) are a group of glycosphingolipids that are highly expressed in brain. Due to their importance for normal brain function and their potential involvement in neurological diseases, development of accurate and sensitive methods for their determination is needed. Here we describe a high-throughput oriented and quantitative method for the determination of STs in cerebrospinal fluid (CSF). The STs were extracted using a fully automated liquid/liquid extraction method and quantified using ultra-performance liquid chromatography coupled to tandem mass spectrometry. With the high sensitivity of the developed method, quantification of 20 ST species from only 100 mu l of CSF was performed. Validation of the method showed that the STs were extracted with high recovery (90%) and could be determined with low inter-and intra-day variation. Our method was applied to a patient cohort of subjects with an Alzheimer's disease biomarker profile. Although the total ST levels were unaltered compared with an age-matched control group, we show that the ratio of hydroxylated/nonhydroxylated STs was increased in the patient cohort. In conclusion, we believe that the fast, sensitive, and accurate method described in this study is a powerful new tool for the determination of STs in clinical as well as preclinical settings.-Blomqvist, M., J. Boren, H. Zetterberg, K. Blennow, J-E. Mansson, and M. Stahlman. High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS.
|
|
| 2. |
- Hollestelle, Antoinette, et al.
(author)
-
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
- 2016
-
In: Gynecologic Oncology. - : Elsevier BV. - 0090-8258 .- 1095-6859. ; 141:2, s. 386-401
-
Journal article (peer-reviewed)abstract
- Objective Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3′ UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast cancer risks as well as clinical outcome associated with rs61764370. Methods Centralized genotyping and analysis were performed for 140,012 women enrolled in the Ovarian Cancer Association Consortium (15,357 ovarian cancer patients; 30,816 controls), the Breast Cancer Association Consortium (33,530 breast cancer patients; 37,640 controls), and the Consortium of Modifiers of BRCA1 and BRCA2 (14,765 BRCA1 and 7904 BRCA2 mutation carriers). Results We found no association with risk of ovarian cancer (OR = 0.99, 95% CI 0.94-1.04, p = 0.74) or breast cancer (OR = 0.98, 95% CI 0.94-1.01, p = 0.19) and results were consistent among mutation carriers (BRCA1, ovarian cancer HR = 1.09, 95% CI 0.97-1.23, p = 0.14, breast cancer HR = 1.04, 95% CI 0.97-1.12, p = 0.27; BRCA2, ovarian cancer HR = 0.89, 95% CI 0.71-1.13, p = 0.34, breast cancer HR = 1.06, 95% CI 0.94-1.19, p = 0.35). Null results were also obtained for associations with overall survival following ovarian cancer (HR = 0.94, 95% CI 0.83-1.07, p = 0.38), breast cancer (HR = 0.96, 95% CI 0.87-1.06, p = 0.38), and all other previously-reported associations. Conclusions rs61764370 is not associated with risk of ovarian or breast cancer nor with clinical outcome for patients with these cancers. Therefore, genotyping this variant has no clinical utility related to the prediction or management of these cancers.
|
|
| 3. |
- Novakova, Lenka, 1984, et al.
(author)
-
Cerebrospinal fluid sulfatide isoforms lack diagnostic utility in separating progressive from relapsing-remitting multiple sclerosis.
- 2023
-
In: Multiple sclerosis and related disorders. - 2211-0356. ; 74
-
Journal article (peer-reviewed)abstract
- Multiple sclerosis (MS) is an immune-mediated demyelinating disorder of the central nervous system. The glycosphingolipid sulfatide, a lipid particularly enriched in the myelin sheath, has been shown to be involved the maintenance of this specific membrane structure. Sulfatide in cerebrospinal fluid (CSF) may reflect demyelination, a dominating feature of MS. We investigated the diagnostic utility of CSF sulfatide isoform levels to separate different courses or phenotypes of MS disease.This was a mono-center, cross-sectional study of relapsing-remitting MS (RRMS) (n=45) and progressive MS (PMS) (n=42) patients (consisting of primary PMS (n=17) and secondary PMS (n=25)) and healthy controls (n=19). In total, 20 sulfatide isoforms were measured in CSF by liquid chromatography-mass spectrometry.CSF total sulfatide concentrations, as well as CSF sulfatide isoform distribution, did not differ across the study groups, and their levels were independent of disease course/phenotype, disease duration, time to conversion to secondary PMS, age, and disability in MS patients.CSF sulfatide isoforms lack diagnostic and prognostic utility as a biomarker for progressive MS.
|
|
| 4. |
- Novakova, Lenka, 1984, et al.
(author)
-
Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS
- 2018
-
In: Journal of Neurochemistry. - : Wiley. - 0022-3042. ; 146:3, s. 322-332
-
Journal article (peer-reviewed)abstract
- Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Several biomarkers including proteins and lipids have been reported in MS cerebrospinal fluid (CSF), reflecting different aspects of the pathophysiology particularly of relapsing-remitting MS (RRMS). Sulfatide, abundant in the myelin sheath and a proposed target for autoimmune attack in MS, has been reported altered in MS CSF. Here, we investigated the potential of CSF sulfatide and its isoforms as biomarkers in MS. A highly sensitive and quantitative mass spectrometry method was employed to determine levels of sulfatide isoforms in CSF from RRMS and progressive MS (PMS) patients, and healthy donors (HD). We demonstrate that levels of total CSF sulfatide and C24:1, C26:1, and C26:1-OH isoforms were significantly increased in PMS compared with RRMS patients and HD, while C23:0-OH was significantly decreased in CSF from PMS patients compared to the other two groups. Multivariate discriminant analysis showed that CSF sulfatide isoform pattern in PMS patients was distinct and non-overlapping with that of RRMS patients and HD. Sulfatide levels did not correlate with tested biomarkers or clinical parameters. The results suggest that CSF sulfatide isoform levels may be used to discriminate the phenotype ofMS and might play a role in the progression of the disease.
|
|
| 5. |
|
|
| 6. |
- Adler, Jan-Olof, et al.
(author)
-
A broad range tagging spectrometer for the MAX-laboratory
- 1997
-
In: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - 0167-5087. ; 388:1-2, s. 17-26
-
Journal article (peer-reviewed)abstract
- A broad range tagging spectrometer together with a new beam transport system for photonuclear experiments at the MAX-laboratory in Lund is described. The spectrometer consists of a quadrupole followed by an Elbek-type dipole and has a large momentum acceptance. It can produce both polarized and unpolarized tagged photons in the energy range 10–80 MeV with an energy resolution of about 300 keV.
|
|
| 7. |
- Anderberg, Mats, 1961-, et al.
(author)
-
Strukturerade intervjuer inom missbruksvården : - som en grund för kunskapsutveckling
- 2009
-
Doctoral thesis (other academic/artistic)abstract
- Anderberg, Mats & Dahlberg, Mikael (2009). Strukturerade intervjuer inom missbruksvården – som en grund för kunskapsutveckling (Structured interviews in substance abuse treatment - as a foundation for the development of knowledge). In the discussion on knowledge development in social work, structured interviews have attracted an increasing amount of attention. The aim of this thesis is to examine and analyze how structured interviews can serve as a basis in the compilation and development of knowledge for practice and research in addiction treatment. More precisely, it means a problematization of the methodological issues that are of central importance in studying treatment outcomes, in which structured interviews form the basis. The methodological aspects in focus here are scientific concepts such as reliability, validity and specific factors in the evaluation of treatment interventions. A further objective is to outline a model for analysis when compiling and evaluating treatment outcome. The five empirical studies have been conducted in their natural context, in organisations in which structured interviews with clients are carried out as an everyday routine and used for e.g. treatment planning. The structured interview DOK (a Swedish abbreviation for Documentation of clients) is used as a basis and an example for the empirical studies in this thesis. The validation studies show that the DOK interview generally attains a good level of reliability and validity, but also contains a small number of variables that do not live up to the requirements which may be imposed. Deficiencies in operationalization and question construction seem to have a large impact. Another conclusion is that it is possible to carry out validation studies, where each variable is examined separately and evaluated with the aid of both sound methodological starting points and relevant statistical theory. Another of the central questions, the thesis addresses, is how structured interviews can be used as a basis for evaluation of treatment. The two studies which highlight this issue show that it is obvious that structured interviews are suitable for such a purpose, through its standardized form and multi-dimensional nature. Validation of structured interviews or evaluation of social interventions should not be reduced to single numbers or values. The multidimensional nature of the structured interview shall also be reflected in the results and analysis. The thesis presents an analysis model for evaluating treatment outcome in relation to two empirical examples and foregoing theoretical starting points. Our view is that structured interviews can provide a link between practice and research and thus contribute to the development of knowledge in social work and substance abuse treatment.
|
|
| 8. |
|
|
| 9. |
- Andersson, S., et al.
(author)
-
Sulfur recirculation for increased electricity production in Waste-to-Energy plants
- 2014
-
In: Waste Management. - : Elsevier BV. - 0956-053X .- 1879-2456. ; 34:1, s. 67-78
-
Journal article (peer-reviewed)abstract
- Sulfur recirculation is a new technology for reducing boiler corrosion and dioxin formation. It was demonstrated in full-scale tests at a Waste to Energy plant in Goteborg (Sweden) during nearly two months of operation. Sulfur was recirculated as sulfuric acid from the flue gas cleaning back to the boiler, thus creating a sulfur loop. The new technology was evaluated by extensive measurement campaigns during operation under normal conditions (reference case) and operation with sulfur recirculation. The chlorine content of both fly ash and boiler ash decreased and the sulfur content increased during the sulfur recirculation tests. The deposit growth and the particle concentration decreased with sulfur recirculation and the dioxin concentration (I-TEQ) of the flue gas was reduced by approximately 25%. Sulfuric acid dew point measurements showed that the sulfuric acid dosage did not lead to elevated SO3 concentrations, which may otherwise induce low temperature corrosion. In the sulfur recirculation corrosion probe exposures, the corrosion rate decreased for all tested materials (16Mo3, Sanicro 28 and Inconel 625) and material temperatures (450 degrees C and 525 degrees C) compared to the reference exposure. The corrosion rates were reduced by 60-90%. Sulfur recirculation prevented the formation of transition metal chlorides at the metal/oxide interface, formation of chromate and reduced the presence of zinc in the corrosion products. Furthermore, measured corrosion rates at 525 degrees C with sulfur recirculation in operation were similar or lower compared to those measured at 450 degrees C material temperature in reference conditions, which corresponds to normal operation at normal steam temperatures. This implies that sulfur recirculation allows for higher steam data and electricity production without increasing corrosion.
|
|
| 10. |
|
|
| 11. |
|
|
| 12. |
- Blomqvist, G, et al.
(author)
-
Association between development of lower lip cancer and tobacco habits
- 1991
-
In: Journal of oral and maxillofacial surgery (Print). - : Elsevier BV. - 0278-2391 .- 1531-5053. ; 49:10, s. 1044-1047; discussion 1048
-
Journal article (peer-reviewed)abstract
- Tobacco use is considered to increase the risk of tumor induction. The purpose of this case-controlled investigation was to assess the association of tobacco habits and development of squamous cell carcinoma of the lower lip. Sixty-one patients treated for lower lip cancer, aged between 42 and 90 years, were studied. Age- and sex-matched healthy controls showed a similar exposure to tobacco in years and a comparable distribution of tobacco habits. Although the mean exposure factor (duration times exposure) was greater in the tumor group, no intimate correlation between lip cancer and tobacco was demonstrated. However, an increased, although small, occurrence of herpes labialis lesions was found in cancer patients. The hypothesis is presented that smokers experiencing recurrent herpes simplex virus 1 (HSV-1) infections are more liable to tumor initiation, which issue will be subjected to a future study.
|
|
| 13. |
|
|
| 14. |
|
|
| 15. |
|
|
| 16. |
|
|
| 17. |
|
|
| 18. |
|
|
| 19. |
|
|
| 20. |
- Blomqvist, Jan, 1946-
(author)
-
Av egen kraft - med andras stöd
- 2013
-
In: Hjälpande möten i vård och omvärld. - Stockholm : Liber. - 9789147105373 ; , s. 182-210
-
Book chapter (other academic/artistic)
|
|
| 21. |
|
|
| 22. |
- Blomqvist, Jan, 1946-
(author)
-
Beyond treatment? : widening the approach to alcohol problems and solutions
- 1998
-
Doctoral thesis (other academic/artistic)abstract
- The dissertation includes four different studies which, from different points of departure, aim to illuminate problems and prospects of social work with alcohol problems in contemporary Sweden.Paper 1 analyses the historical succession of predominant public images of, and societal responses to, alcohol problems in Sweden during the past century. The analysis distinguishes between a moral, an enlightenment, a medical and a compensatory approach to these problems. The main development in society's handling of alcohol problems is described to have been a gradual shift from the moral to the medical approach, despite the fact that the compensatory approach is in many respects the one most akin to the general social policy ideal of Sweden. The paper concludes by discussing the future prospects of community-based approaches to alcohol problems, relying on the assumptions of the latter approach.Paper 2 scrutinises, based on reanalyses of a variety of empirical sources, developments within residential care for substance misusers in Sweden during the past three decades. The results of these analyses belie several popular notions about the role of institutions in social work with alcohol problems. Thus they show, in contrast to claims in some public reports, that the annual number of alcohol misusers cared for decreased during most of the 1980s, already before the major decrease in the beginning of the 1990s. Further, they show that residential care has - despite a growing "treatment rhetoric" over the years - been primarily utilised for a rather small group of long-term misusers with severe social problems, and with a pattern of repeated - and often prematurely interrupted - admissions and readmissions over a long succession of years.Paper 3 reviews and discusses the significance of research on "spontaneous recovery" from substance misuse and treatment outcome research. The paper outlines and develops further the notion that there may be "common elements" or mechanisms in all successful change processes, whether these include professional interventions or not. Formal treatment is further discussed in terms of temporary interventions in the client's life course, which may, if successful, facilitate and accelerate "naturally" occurring rehabilitation processes. The paper concludes by proposing a closer integration of research on "spontaneous recovery" and treatment outcome research, as a way of learning more about the potential interplay between life events, formal interventions and change of lifestyle.Paper 4 is an account of an attempt to put the ideas of Paper 3 into practice, by comparing subjects who recovered from severe alcohol problems without formal assistance, with subjects who were assisted in doing so. Comparisons were made with regard to drinking patterns and occurrences of significant life events during a period of time, encapsulating four years before and two years after the resolution, and with regard to subjects' attributions as to what initiated and maintained recovery. As regards drinking patterns and event occurrences, comparisons were further made with assisted and unassisted subjects with current alcohol problems. The results indicate that initial attempts to solve the drinking problem and initial help-seeking, as well as long-term maintenance of the resolution, are influenced by environmental factors, operating outside the context of formal treatment. Unassisted remitters showed greater social stability before the resolution than assisted remitters, more often stated positive incentives for trying to change their lifestyle, and more often tapered their drinking gradually. The results underline the need to consider and try to harness contextual factors when planning individually directed and preventive measures.In an introductory chapter, the four papers are linked together by an examination of prevailing theoretical models of alcohol problems, and the outlining of an overarching perspective that accounts for habitual ex-cessive drinking as a "central activity" in the drinker's way of life. Finally, some joint implications of the four papers, with regard to social work with alcohol problems, and with regard to future research, are discussed.
|
|
| 23. |
|
|
| 24. |
|
|
| 25. |
|
|
| 26. |
|
|
| 27. |
- Blomqvist, Jan Einar
(author)
-
Educating entrepreneurs for handling the innovation process with new product development in industry or in own formed company
- 1989
-
In: SEFITALIA89. - Neapel : University of Naples. ; , s. 15-21
-
Conference paper (peer-reviewed)abstract
- At Halmstad University College on the west coast of Sweden, we have a unique education in innovation and entrepreneurial engineering. The three year program provides the candidates with a braod technical economical education with special emphasize on handling the innovation process and running new product development projects. This is the summing up og 10 years experience during which 140 innovation engineers have been graduated.
|
|
| 28. |
- Blomqvist, Jan Einar, 1936-
(author)
-
Innovation engineering : Pedagogic strategy of Halmstad University
- 1992
-
In: Product development in engineering education. - Halmstad : Halmstad University. - 9163011034 ; , s. 11-18
-
Conference paper (peer-reviewed)abstract
- At small Halmstad University we have, for the past 13 years, a unique educational program in innovation engineering. The three-year educational program provides the candidates with a broad technical and economical education with special emphasise on handling the innovation process and running new product development projects. An optional fourth year, entitled innovation management, focuses on leadership, innovation, and the choices of technology in multinational companies. This is the summing up of 13 years of experience, during which 286 innovation engineers received an education (even if 22% left with one or two unwritten exams).
|
|
| 29. |
|
|
| 30. |
- Blomqvist, Jan
(author)
-
From faith to knowledge? Reflections on some prerequisites for evidence-based addiction care in Sweden
- 2007
-
Conference paper (pop. science, debate, etc.)abstract
- It has often been claimed that the historical development of addiction care reflects ideological, political, and economical changes, and/or shifting therapeutic crazes, constantly failing to live up to what they offer, rather than the continuous march of progress in science. During the past decades, however, evidence-based practice (EBP) has become a well established doctrine in many parts of the health and welfare field, including addiction care. A recent example of this is the National guidelines for addiction care and treatment, issued by the Swedish National Board of Health and Welfare in spring 2007. According to the most eager proponents, the acceptance of the EBP doctrine will bring an end to ideological and religious beliefs, self-assured convictions, and pure guesswork as a ground for treatment practice, replacing them with valid empirical facts and certain scientific proof. However, these claims have not gone uncontested, and some have claimed the new doctrine to represent just another “promise for the future” that will never be fulfilled. For one thing, evidence-based medicine (EBM), which is often described as the root of EBP, typically distinguishes three important sources for informing practice, namely dependable clinical experience, external scientific proof, and patients’ needs and wishes. However, many critics have claimed that EBP in the general welfare field has often come to mean “based on RCT studies”, thus considering mainly or only one of these sources. To a large extent, this critique can be claimed to be valid in the case of the Swedish National guidelines. Other objections that have been directed at these guidelines have concerned flawed and partly contradictory scientific underpinning, partial lack of references for conclusions drawn, inconsistencies with regard to the use of various review methods and so on. Valid as these objections may be claimed to be, this contribution will rather scrutinize the same guidelines from the point of view of the practice field. Based on an appraisal of (i) the historical role of the treatment system, (ii) the predominating views of the character of the problems attended to, (iii) who the clients cared for by the system are, (iv) the typical modus operandi of the same system, and (v) what we know about how recovery from addiction problems actually comes about, some obvious problems and drawbacks, but also some potential benefits of the new guidelines will be highlighted.
|
|
| 31. |
- Blomqvist, Jan, 1946-, et al.
(author)
-
How should substance use problems be handled? : popular views in Sweden, Finland, and Canada
- 2014
-
In: Drugs and Alcohol Today. - 1745-9265. ; 14:1, s. 19-30
-
Journal article (peer-reviewed)abstract
- Purpose – Although the way in which, for example, substance use problems are conceived and reacted to (by experts and treatment professionals but also by the environment), can have vast consequences for those directly or indirectly concerned, there is little systematic knowledge about how various preferred approaches differ between types of problems and sociocultural settings. In an ambition to at least partly mend this gap, this paper aims to compare how the general public in Sweden, Finland, and Canada appraise four generically different approaches to dealing with substance use problems, as these are applied to problem use of alcohol, cannabis, heroin, and cigarettes.Design/methodology/approach – The paper uses data from three national surveys, aimed at uncovering how representative population samples from Sweden, Finland, and Canada perceive and understand the character of, and the proper way of handling, various addictive problems. Data from these surveys have been used to discern and operationalize four basic “models of helping and coping” as these have been outlined by Brickman et al. (1982). The analysis has aimed at investigating how the popular preferences for either of these models vary with type of addiction (to cigarettes, alcohol, cannabis, and other (“hard”) drugs, national setting, and potentially important respondent characteristics.Findings – The results point to large differences between the ways in which the general public understands the proper way of handling the four types of addiction, and shows, for example, that addiction to “hard” drugs is predominantly perceived as a matter for expert treatment, whereas smoking, or addiction to cigarettes, is more often perceived as a bad habit which the user is able to break on her/his own. In addition, the popularity of different handling models is found to vary between countries, and with personal characteristics such as gender, age, and substance use experiences.Originality/value – The study is one of few that have systematically tried to find out how various forms of substance use problems, or addiction, are conceived and reacted to in various national and social settings.
|
|
| 32. |
- Blomqvist, Jan
(author)
-
Is it really more treatment or ’better methods’ that we need?
- 2008
-
Conference paper (pop. science, debate, etc.)abstract
- After years of relative neglect addiction care and treatment has, during the new millennium, again come to the attention of authorities and policy makers in Sweden. To a large part, this new interest has taken the form of developing addiction care into an “evidence-based practice” by the implementation of scientifically underpinned treatment methods. Another part has been the allocation of special resources to increase the use of coercive care. Based on results from topical research on the state-of-art of the Swedish addiction care system, and on “self-change” from various forms of addiction problems, the presentation will argue that neither “more resources” nor “better methods” are necessarily what is most urgently needed to develop more responsive and better-working means to counter addiction problems in Sweden. Among topics that will be discussed in the presentation is the “revolving-door” character of the present care system, why the majority of problem substance users refrain from seeking contact with the system, and some problems attached to the EBP concept as a basis for addiction care. As an alternative, the presentation will point to the need for broader and more flexible social strategies to counter addiction problems.
|
|
| 33. |
|
|
| 34. |
- Blomqvist, Jan
(author)
-
Långtidsförlopp vid narkotikamissbruk
- 2006
-
In: Faktaunderlag till Nationella riktlinjer för missbruks- och beroendevård. - Stockholm : Socialstyrelsen. ; , s. 87-107
-
Book chapter (other academic/artistic)
|
|
| 35. |
|
|
| 36. |
- Blomqvist, Jan, et al.
(author)
-
Modelling of furniture experiments with zone models
- 1985
-
In: Fire and Materials. - : Wiley. - 0308-0501 .- 1099-1018.
-
Reports (other academic/artistic)abstract
- The Harvard Computer Fire Code Mark V has been used to simulate full-scale Furniture fires. Simulations were run with one sofa burning in the open and another burning in a small room. To obtain better agreement between experiment and simulation, changes were made in the code to include heating of the lower surfaces in the room. A simulation of a mattress test, conducted at NBS, is included. Comparison with a zone model using a different plume equation is also presented.
|
|
| 37. |
|
|
| 38. |
- Blomqvist, Jan, et al.
(author)
-
'More cure and less control' or 'more care and lower costs'? Recent changes in services for problem drug users in Stockholm and Sweden
- 2009
-
In: Drugs. - : Informa UK Limited. - 0968-7637 .- 1465-3370. ; 16:6, s. 479-496
-
Journal article (peer-reviewed)abstract
- This article deals with the development of drug services in Stockholm, Sweden since the mid-1990s. Initially, data were collected as part of a European Union comparative study of the development of drug services in six major European cities. However, the present article uses these data to analyse to what extent the traditional 'Swedish model' of dealing with narcotic drugs can be said to have come to a crossroad. The article describes and analyses changes in drug use, and in the structure, organization and utilization of social services based, as well as healthcare-based drug services in Stockholm during the past decade. As pointed out in the article, the 'drug-free society' is still the ultimate goal of Swedish drug policy. However, as the Stockholm example hints, when it comes to the care and treatment of individual drug problems, there seems to be an on-going shift, from in-patient treatment towards measures such as substitution treatment, outpatient care and housing. The article discusses whether these changes signify a softening of Sweden's restrictive drug policy, or whether they rather point to a 're-medicalization' of drug services, and shift in focus from 'cure' and social re-integration towards a focus on 'care' and on attempts to avoid 'public nuisance'.
|
|
| 39. |
|
|
| 40. |
|
|
| 41. |
|
|
| 42. |
|
|
| 43. |
|
|
| 44. |
|
|
| 45. |
|
|
| 46. |
|
|
| 47. |
|
|
| 48. |
|
|
| 49. |
|
|
| 50. |
- Blomqvist, Jan, 1946-
(author)
-
Perceptions of addiction and recovery in Sweden : The influence of respondent characteristics
- 2012
-
In: Addiction Research and Theory. - : Informa UK Limited. - 1058-6989 .- 1606-6359 .- 1476-7392. ; 20:5, s. 435-446
-
Journal article (peer-reviewed)abstract
- Respondents to a representative population survey were asked to rate four psychoactive substances (tobacco, alcohol, cannabis and ‘hard’ drugs) with regard to their severity to society and addictiveness, as well as the options for recovery, with and without treatment, from an addiction to the same substances. This article explores if and how these ratings differ with regard to respondents’ socio-demographic characteristics, their own and close persons’ substance use experiences, and, their attitudes towards people with substance use problems. Data were analysed using descriptive statistics and logistic or linear regressions. Although the main difference goes between respondents’ perceptions of various substances and addictions, the results also point to some interesting differences with regard to respondents’ experiences and characteristics. Thus for example, women and respondents with no personal substance use experiences, tend to play up the severity and addictiveness of most substances, and to play down the options for untreated recovery from an addiction, whereas current risk users tend to take an opposite view. Main interpretations are that there is a general tendency to exaggerate the hazards of and risks with habits that are perceived as unfamiliar and alien, that current risk users at the same time dwell on a ‘false hope’ of being able to quit, and that women are, for various reasons, more inclined than men to worry about their own substance use habits, as well as those in their close environment. Potential implications, for further research as well as for policy and prevention, are discussed.
|
|
