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| 4. |
- Bonita, Ruth, et al.
(författare)
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Linnaeus : Alive and well
- 2011
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Ingår i: Global Health Action. - : Co-Action Publishing. - 1654-9716 .- 1654-9880. ; 4, s. 5760-2
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Tidskriftsartikel (refereegranskat)
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| 9. |
- Brändström, Anders, et al.
(författare)
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Clustering across generations : a comparative analysis of infant mortality in 19th century Sweden
- 2007
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Ingår i: ESSHC Conference in Lisbon, 26 February-1 March, 2008.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Many studies in the past have emphasized the positive correlation between infant mortality and fertility, but how this operates remain unclear. In this paper, we investigate these interdependent processes using data from the Demographic Data base at Ume{\aa} University. More specifically, we have data from regions in the northern part of Sweden, starting in the fifteenth century and ending around the year 1900. In an earlier paper, we have studied the intergenerational aspects of infant mortality and in this paper we incorporate fertility. We investigate the interaction between the two processes and how patterns are tranferred from generation to generation.
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| 13. |
- Brändström, Anders, et al.
(författare)
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Determinants of home care utilization among the Swedish old : nationwide register-based study
- 2022
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Ingår i: European Journal of Ageing. - : Springer. - 1613-9372 .- 1613-9380. ; 19, s. 651-662
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Tidskriftsartikel (refereegranskat)abstract
- Since the 1990s, Sweden has implemented aging-in-place policies increasing the share of older adults dependent on home care instead of residing in care homes. At the same time previous research has highlighted that individuals receive home care at a higher age than before. Consequently, services are provided for a shorter time before death, increasing reliance on family and kin as caregivers. Previous studies addressing how homecare is distributed rely primarily on small surveys and are often limited to specific regions. This study aims to ascertain how home care services are distributed regarding individual-level factors such as health status, living arrangements, availability of family, education, and socioeconomic position. To provide estimates that can be generalized to Sweden as a whole, we use register data for the entire Swedish population aged 65 + in 2016. The study's main findings are that home care recipients and the amount of care received are among the oldest old with severe co morbidities. Receiving home care is slightly more common among women, but only in the highest age groups. Childlessness and socioeconomic factors play a small role in who receives home care or not. Instead, the primary home care recipients are those older adults living alone who lack direct support from family members residing in the same household.
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| 20. |
- Brändström, Anders, 1955-, et al.
(författare)
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Inledning
- 2012
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Ingår i: Människan, arbetet och historien. - Umeå : Umeå universitet. - 9789174594737 ; , s. 5-7
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 21. |
- Brändström, Anders, et al.
(författare)
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Introduction
- 1995
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Ingår i: Swedish Urban Demography during Industrialization. - Umeå : Umeå universitet. - 9171911146 ; , s. 7-12
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 22. |
- Brändström, Anders, et al.
(författare)
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Introduction
- 2000
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Ingår i: Population Dynamics during Industrialization. - Umeå : Umeå universitet. - 9171914218 ; , s. 5-10
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 23. |
- Brändström, Anders, et al.
(författare)
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Introduction
- 2002
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Ingår i: Hygiea Internationalis. - : Linkoping University Electronic Press. - 1403-8668 .- 1404-4013. ; 3:1, s. 7-11
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 27. |
- Brändström, Anders, et al.
(författare)
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Retirement, home care and the importance of gender
- 2021
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Ingår i: Historical Life Course Studies. - : International Institute of Social History. - 2352-6343. ; 10, s. 172-179
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Tidskriftsartikel (refereegranskat)abstract
- In recent decades elderly care policies in Sweden have been characterized by a marked shift from institutional care to home care. Previous research has highlighted how this has resulted in the elderly receiving care at a higher age and increased reliance on family and kin for providing care. Using register data for the entire Swedish population aged 65+ in 2016, we analyze how home care services in contemporary Sweden distribute regarding individual-level factors such as gender, health status, living arrangements, and closeness to kin. By far, the most critical determinants of receiving home care are age, health status, and whether the elderly are living alone or not. Although our results do not discard that access to kin has become more important, our results show that childlessness and geographical proximity to adult children play a minor role for differentials in the reception of home care. The main conduit for informal care instead takes the form of spousal support. Gender plays a role in how living arrangements influence the probability of receiving home care, where cohabiting women are significantly more likely to receive care than cohabiting men. We interpret this as a result of women, on average, being younger than their male partners and more easily adopting caregivers' roles. This gendered pattern is potentially explained by the persistence of more traditional gender roles prevailing in older cohorts.
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- Brändström, Helge, 1953-
(författare)
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Accidental hypothermia and local cold injury : physiological and epidemiological studies on risk
- 2012
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Background: (Papers I and II) The objectives were to first determine incidence and contributing factors to cold-related injuries in northern Sweden, both those that led to hospitalization and those that led to fatality. (Papers III and IV) A further aim was to assess post-cooling hand-rewarming responses and effects of training in a cold environment, both on fingertip rewarming and on function of the autonomic nervous system, to evaluate if there was adaptation related to prolonged occupational cold exposure.Methods: In a retrospective analysis, cases of accidental cold-related injury with hospital admission in northern Sweden during 2000-2007 were analyzed (Paper I). Cases of fatal hypothermia in the same region during 1992-2008 were analyzed (Paper II). A cohort of volunteers was studied before and after many months of occupational cold exposure. Subject hand rewarming response was measured after a cold hand immersion provocation and categorized as slow, moderate or normal in rewarming speed. This cold provocation and rewarming assessment was performed before and after their winter training. (Paper III). Heart rate variability (HRV) was analyzed from the same cold provocation/recovery sequences (Paper IV).Results: (Paper I) For the 379 cases of hospitalization for cold-related injury, annual incidences for hypothermia, frostbite, and drowning were 3.4/100,000, 1.5/100,000, and 1.0/100,000 inhabitants, respectively. Male gender was more frequent for all categories. Annual frequencies for hypothermia hospitalizations increased during the study period. Hypothermia degree and distribution of cases were 20 % mild (between 32 and 35ºC), 40% moderate (31.9 to 28ºC), and 24% severe (< 28ºC), while 12% had temperatures over 35.0ºC. (Paper II) The 207 cases of fatal hypothermia showed an annual incidence of 1.35 per 100,000 inhabitants, 72% in rural areas, 93% outdoors, 40% found within 100 meters of a building. Paradoxical undressing was documented in 30%. Ethanol was detected in femoral vein blood in 43%. Contributing co-morbidity was common including heart disease, previous stroke, dementia, psychiatric disease, alcoholism, and recent trauma. (Paper III) Post-training, baseline fingertip temperatures and cold recovery variables in terms of final rewarming fingertip temperature and vasodilation time increased significantly in moderate and slow rewarmers. Cold-related injury (frostbite) during winter training occured disproportionately more often in slow rewarmers (4 of the 5 injuries). (Paper IV) At ‘pre- winter-training’, normal rewarmers had higher power for low frequency and high frequency heart rate variability. After cold acclimatization (post-training), normal rewarmers showed lower resting power values for the low frequency and high frequency heart rate variability components. Conclusions: Hypothermia and cold injury continues to cause injury and hospitalization in the northern region of Sweden. Assessment and management is not standardized across hospitals. With the identification of groups at high risk for fatal hypothermia, it should be possible to reduce the incidence, particularly for highest risk subjects; rural, living alone, alcohol-imbibing, and psychiatric diagnosis-carrying citizens. Long-term cold-weather training may affect hand rewarming patters after a cold provocation, and a warmer baseline hand temperature with faster rewarming after a cold provocation may be associated with less general risk for frostbite. Heart rate variability results support the conclusion that cold adaptation in the autonomic nervous system occurred in both groups, though the biological significance of this is not yet clear.
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| 34. |
- Brändström, Helge, et al.
(författare)
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Fatal hypothermia : an analysis from a sub-arctic region
- 2012
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Ingår i: International Journal of Circumpolar Health. - : Informa UK Limited. - 1239-9736 .- 2242-3982. ; 71:0, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Objectives. To determine the incidence as well as contributing factors to fatal hypothermia.Study design. Retrospective, registry-based analysis.Methods. Cases of fatal hypothermia were identified in the database of the National Board of Forensic Medicine for the 4 northernmost counties of Sweden and for the study period 1992-2008. Police reports, medical records and autopsy protocols were studied.Results. A total of 207 cases of fatal hypothermia were noted during the study period, giving an annual incidence of 1.35 per 100,000 inhabitants. Seventy-two percent occurred in rural areas, and 93% outdoors. Many (40%) were found within approximately 100 meters of a building. The majority (75%) occurred during the colder season (October to March). Some degree of paradoxical undressing was documented in 30%. Ethanol was detected in femoral vein blood in 43% of the victims. Contributing co-morbidity was common and included heart disease, earlier stroke, dementia, psychiatric disease, alcoholism, and recent trauma.Conclusions. With the identification of groups at high risk for fatal hypothermia, it should be possible to reduce risk through thoughtful interventions, particularly related to the highest risk subjects (rural, living alone, alcohol-imbibing, and psychiatric diagnosis-carrying) citizens.
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| 35. |
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| 36. |
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| 37. |
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| 38. |
- Edvinsson, Sören, 1953-, et al.
(författare)
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Folkhälsans historia från 1870 till nutid
- 1997
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Ingår i: Sundsvalls historia del 2. - Sundsvall : Stadshistoriska Kommittén. - 9188186075
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 39. |
- Edvinsson, Sören, 1953-, et al.
(författare)
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Folkhälsans utveckling - tiden före 1870
- 1996
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Ingår i: Sundsvalls historia del 1. - Sundsvall : Stadshistoriska kommittén. - 9188186075
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 40. |
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| 41. |
- Edvinsson, Sören, 1953-, et al.
(författare)
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Introduction
- 2002
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Ingår i: Hygiea Internationalis. - Linköping : Linköping University Electronic Press. - 1403-8668 .- 1404-4013. ; 3:1, s. 7-11
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Tidskriftsartikel (refereegranskat)
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| 42. |
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| 43. |
- Frost, Anders, et al.
(författare)
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Interleukin-13 inhibits cell proliferation and stimulates interleukin-6 formation in isolated human osteoblasts.
- 1998
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Ingår i: The Journal of clinical endocrinology and metabolism. - 0021-972X. ; 83:9, s. 3285-9
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Tidskriftsartikel (refereegranskat)abstract
- Interleukin-13 (IL-13) is a recently identified cytokine that is secreted by activated T cells and regulates inflammatory responses. We have investigated the effects of IL-13 on isolated human osteoblast-like cells (hOB). IL-13 dose-dependently (1-100 pmol/L) reduced the incorporation rate of [3H]thymidine in hOB cells by more than 50%. Using a cell metabolic assay as well as direct cell counting, we found that treatment with IL-13 lead to a decrease in hOB cell number. The effect was both time and dose dependent, and after 12 days of culture, treatment with IL-13 (0.1 nmol/L) caused a 70% decrease in the number of cells. Also, IL-13 increased the levels of IL-6 messenger ribonucleic acid in hOBs, as measured by ribonuclease protection assay, and stimulated secretion of IL-6 into culture supernatants. In conclusion, IL-13 inhibits cell proliferation and increases IL-6 formation in human osteoblasts. Our findings suggest that IL-13 may cause bone loss due to impaired osteoblastic growth and IL-6-induced osteoclast recruitment.
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| 44. |
- Hjälm, Anna, 1977-
(författare)
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A family landscape : On the geographical distances between elderly parents and adult children in Sweden
- 2011
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- With a background in the ageing of the population and the new challenges facing individuals, families and the welfare state, the aim of this thesis is to analyse the changing family landscape and the geographical distances between elderly parents and adult children. The thesis consists of four empirical studies derived from three different sources of data: In the first paper (Paper I), historical population data is combined with modern register data for two Swedish regions. In the second and third papers, individual-level register data covering the entire Swedish population serves as the empirical starting point. The fourth paper leaves the registers aside and builds upon interviews. Paper I provides an introduction and historical background to the question of intergenerational geographical proximity and distance. The paper analyses intergenerational distances and seeks to compare and discuss the significance of the variations. It is shown that concerning extreme proximity a great decrease has occurred over 200 years, however when it comes to having kin within reach the decrease is less dramatic, and that now, just as then, a majority of elderly parents have an adult child within reach. The article concludes that even though geographical distances between generations vary over time and space, no clear linear trend towards intergenerational geographical separation can be established. In Paper II we analyse some features and trends in intergenerational distances in Sweden. We find that 10% of all elderly parents have at least one child living very close and that a majority, 85%, have an adult child within reach. The study shows no clear trend towards increasing intergenerational separation, but suggests that periods of intense societal restructuring, such urbanisation, can lead to spells of increased intergenerational separation on an aggregated level. Paper III investigates whether, and to what extent, elderly parents and adult children move close to each other. We find that even though the older generation makes up a smaller share of the moves made, when they do move they are more likely to move closer to an adult child. Further, having more than one relative at a destination adds to the attraction, and that older elderly are less likely to move close to a child than younger elderly. One interpretation is that young-old parents serve as a resource for their adult children, while older elderly are more influenced by the need for welfare state based assistance. The last paper, IV, returns to the elderly parents living very close to an adult child. In interviews with 14 elderly the aim of the paper is to gain new understanding about the interaction between intergenerational proximity, assistance and the meaning of being close. Some of the issues raised in the paper relate to migration histories, reciprocity and independence.
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| 45. |
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| 46. |
- Kumie, Abera, et al.
(författare)
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Sources of variation for indoor nitrogen dioxide in rural residences of Ethiopia
- 2009
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Ingår i: Environmental Health. - 1476-069X. ; 8, s. 51-
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Unprocessed biomass fuel is the primary source of indoor air pollution (IAP) in developing countries. The use of biomass fuel has been linked with acute respiratory infections. This study assesses sources of variations associated with the level of indoor nitrogen dioxide (NO2).MATERIALS AND METHODS: This study examines household factors affecting the level of indoor pollution by measuring NO2. Repeated measurements of NO2 were made using a passive diffusive sampler. A Saltzman colorimetric method using a spectrometer calibrated at 540 nm was employed to analyze the mass of NO2 on the collection filter that was then subjected to a mass transfer equation to calculate the level of NO2 for the 24 hours of sampling duration. Structured questionnaire was used to collect data on fuel use characteristics. Data entry and cleaning was done in EPI INFO version 6.04, while data was analyzed using SPSS version 15.0. Analysis of variance, multiple linear regression and linear mixed model were used to isolate determining factors contributing to the variation of NO2 concentration.RESULTS: A total of 17,215 air samples were fully analyzed during the study period. Wood and crop were principal source of household energy. Biomass fuel characteristics were strongly related to indoor NO2 concentration in one-way analysis of variance. There was variation in repeated measurements of indoor NO2 over time. In a linear mixed model regression analysis, highland setting, wet season, cooking, use of fire events at least twice a day, frequency of cooked food items, and interaction between ecology and season were predictors of indoor NO2 concentration. The volume of the housing unit and the presence of kitchen showed little relevance in the level of NO2 concentration.CONCLUSION: Agro-ecology, season, purpose of fire events, frequency of fire activities, frequency of cooking and physical conditions of housing are predictors of NO2 concentration. Improved kitchen conditions and ventilation are highly recommended.
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| 47. |
- Kurbasic, Azra, et al.
(författare)
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Gene-Lifestyle Interactions in Complex Diseases : Design and Description of the GLACIER and VIKING Studies
- 2014
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Ingår i: Current nutrition reports. - : Springer Science and Business Media LLC. - 2161-3311. ; 3:4, s. 400-411
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Tidskriftsartikel (refereegranskat)abstract
- Most complex diseases have well-established genetic and non-genetic risk factors. In some instances, these risk factors are likely to interact, whereby their joint effects convey a level of risk that is either significantly more or less than the sum of these risks. Characterizing these gene-environment interactions may help elucidate the biology of complex diseases, as well as to guide strategies for their targeted prevention. In most cases, the detection of gene-environment interactions will require sample sizes in excess of those needed to detect the marginal effects of the genetic and environmental risk factors. Although many consortia have been formed, comprising multiple diverse cohorts to detect gene-environment interactions, few robust examples of such interactions have been discovered. This may be because combining data across studies, usually through meta-analysis of summary data from the contributing cohorts, is often a statistically inefficient approach for the detection of gene-environment interactions. Ideally, single, very large and well-genotyped prospective cohorts, with validated measures of environmental risk factor and disease outcomes should be used to study interactions. The presence of strong founder effects within those cohorts might further strengthen the capacity to detect novel genetic effects and gene-environment interactions. Access to accurate genealogical data would also aid in studying the diploid nature of the human genome, such as genomic imprinting (parent-of-origin effects). Here we describe two studies from northern Sweden (the GLACIER and VIKING studies) that fulfill these characteristics.
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| 48. |
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| 49. |
- Poveda, Alaitz, et al.
(författare)
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The heritable basis of gene–environment interactions in cardiometabolic traits
- 2017
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Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 60:3, s. 442-452
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Tidskriftsartikel (refereegranskat)abstract
- Aims/hypothesis: Little is known about the heritable basis of gene–environment interactions in humans. We therefore screened multiple cardiometabolic traits to assess the probability that they are influenced by genotype–environment interactions. Methods: Fourteen established environmental risk exposures and 11 cardiometabolic traits were analysed in the VIKING study, a cohort of 16,430 Swedish adults from 1682 extended pedigrees with available detailed genealogical, phenotypic and demographic information, using a maximum likelihood variance decomposition method in Sequential Oligogenic Linkage Analysis Routines software. Results: All cardiometabolic traits had statistically significant heritability estimates, with narrow-sense heritabilities (h2) ranging from 24% to 47%. Genotype–environment interactions were detected for age and sex (for the majority of traits), physical activity (for triacylglycerols, 2 h glucose and diastolic BP), smoking (for weight), alcohol intake (for weight, BMI and 2 h glucose) and diet pattern (for weight, BMI, glycaemic traits and systolic BP). Genotype–age interactions for weight and systolic BP, genotype–sex interactions for BMI and triacylglycerols and genotype–alcohol intake interactions for weight remained significant after multiple test correction. Conclusions/interpretation: Age, sex and alcohol intake are likely to be major modifiers of genetic effects for a range of cardiometabolic traits. This information may prove valuable for studies that seek to identify specific loci that modify the effects of lifestyle in cardiometabolic disease.
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