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Sökning: WFRF:(Brandt Mikkel)

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1.
  • Andersen, Lars L, et al. (författare)
  • Effect of physical exercise on workplace social capital: cluster randomized controlled trial
  • 2015
  • Ingår i: Scandinavian Journal of Public Health. - : SAGE Publications. - 1651-1905 .- 1403-4948. ; 43:8, s. 810-818
  • Tidskriftsartikel (refereegranskat)abstract
    • While workplace health promotion with group-based physical exercise can improve workers' physical health, less is known about potential carry-over effects to psychosocial factors. This study investigates the effect of physical exercise on social capital at work.
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2.
  • Andersen, Lars L, et al. (författare)
  • Factors associated with high physical exertion during manual lifting : Cross-sectional study among 200 blue-collar workers
  • 2018
  • Ingår i: Work. - 1875-9270. ; 59:1, s. 59-66
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: High physical exertion during work is a risk factor for back pain and long-term sickness absence.OBJECTIVE: To investigate which factors are associated with physical exertion during manual lifting.METHODS: From 14 workplaces across Denmark, 200 blue-collar workers reported perceived physical exertion (Borg-CR10) during manual lifting from floor to table height of 5, 10, 20 and 30 kg at the beginning and end of the working day. The workers also responded to a questionnaire and went through testing of isometric back muscle strength. Associations were modelled using logistic regression analysis controlled for various confounders. The outcome was dichotomized into low (0-4) and high (5-10) physical exertion.RESULTS: Gender (OR 8.57 [95% CI 4.46-16.46] for women), load (OR 4.22 [95% CI 3.58-4.97] for each 5-kg increase), back muscle strength (OR 0.43 [95% CI 0.23-0.83] for high), and back pain intensity (OR 2.80 [95% CI 1.43-5.48] for high) were associated with high perceived physical exertion. Age, smoking, Body Mass Index (BMI), and time of the day were not associated with physical exertion.CONCLUSIONS: Gender, load, back muscle strength and back pain influence physical exertion during manual lifting in blue-collar workers. These factors should be considered when planning work with manual lifting for individual workers.
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3.
  • Feng, Shaohong, et al. (författare)
  • Dense sampling of bird diversity increases power of comparative genomics
  • 2020
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 587:7833
  • Tidskriftsartikel (refereegranskat)abstract
    • Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity(1-4). Sparse taxon sampling has previously been proposed to confound phylogenetic inference(5), and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from 92.4% of bird families-including 267 newly sequenced genomes produced for phase II of the Bird 10,000 Genomes (B10K) Project. We use this comparative genome dataset in combination with a pipeline that leverages a reference-free whole-genome alignment to identify orthologous regions in greater numbers than has previously been possible and to recognize genomic novelties in particular bird lineages. The densely sampled alignment provides a single-base-pair map of selection, has more than doubled the fraction of bases that are confidently predicted to be under conservation and reveals extensive patterns of weak selection in predominantly non-coding DNA. Our results demonstrate that increasing the diversity of genomes used in comparative studies can reveal more shared and lineage-specific variation, and improve the investigation of genomic characteristics. We anticipate that this genomic resource will offer new perspectives on evolutionary processes in cross-species comparative analyses and assist in efforts to conserve species. A dataset of the genomes of 363 species from the Bird 10,000 Genomes Project shows increased power to detect shared and lineage-specific variation, demonstrating the importance of phylogenetically diverse taxon sampling in whole-genome sequencing.
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4.
  • Jakobsen, Markus Due, et al. (författare)
  • Characterization of Occupational Lifting Patterns with Exposure Variation Analysis. Cross-sectional Workplace Study among Blue-Collar Workers
  • 2022
  • Ingår i: Annals of Work Exposures and Health. - : Oxford University Press (OUP). - 2398-7308 .- 2398-7316. ; 66:7, s. 863-877
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVES: To investigate and characterize the influence of sex, age, muscle strength, and cardiovascular fitness on manual lifting patterns using exposure variation analysis (EVA) during a full working day among blue-collar workers.METHODS: Muscular activity (surface electromyography [sEMG]) of the thigh, low-back, and shoulder was measured throughout the working day in 173 employees with manual lifting tasks from 14 workplaces. Relative sEMG loading was expressed as % of maximal voluntary contraction (MVC). As an additional and more practically oriented analysis, calibration of load from standardized box lifts (5, 10, 20, and 30 kg) identified corresponding sEMG values in kg. Using an EVA 'lifting periods' of [1 to 5, >5 to 10, >10 to 20, >20 to 30, and >30] kg in time intervals [0 to 0.5, >0.5 to 1, >1 to 2, >2 to 5, >5 to 10, and >10] s were identified. Arm elevation and back inclination were measured using accelerometers.RESULTS: Females and older workers (≥50 years) primarily used the thighs for lifting and were exposed to more frequent thigh muscle 'lifting periods' of varying duration and load and performed more thigh lifts >30 kg and >60% of MVC compared with males and younger workers (P < 0.05). Females had less brief shoulder lifting periods and more work with bent back >30° than the males (P < 0.05), whereas stronger workers performed more work with elevated arm >60° and >90° than workers with low muscle strength (P < 0.05). However, besides a single difference where workers with lower cardiovascular fitness were exposed to more light (1-5 kg) and moderate duration (5-10 s) trapezius loading, the number of lifting periods was not affected by muscle strength nor cardiovascular fitness (P > 0.05).CONCLUSIONS: This EVA demonstrated sex- and age-related differences in exposure to lifting periods involving shoulder and thigh muscles.
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5.
  • Jakobsen, Markus Due, et al. (författare)
  • Estimation of physical workload of the low-back based on exposure variation analysis during a full working day among male blue-collar workers. Cross-sectional workplace study
  • 2018
  • Ingår i: Applied Ergonomics. - : Elsevier BV. - 0003-6870. ; 70, s. 127-133
  • Tidskriftsartikel (refereegranskat)abstract
    • This study aims to quantify physical workload of the low-back using exposure variation analysis (EVA) during a full working day among blue-collar workers with manual lifting tasks. One hundred and ten male employees (39 warehouse workers, 27 operators, 24 postal workers and 20 slaughterhouse workers) with manual lifting tasks from 12 workplaces participated. The workers performed standardized box lifts using 5, 10, 20 and 30 kg before and after a working day. Muscular activity of the low-back was measured throughout the working day using surface electromyography (sEMG). Corresponding sEMG-values for 0–30 kg lifts were identified using linear regression. EVA at exposure levels corresponding to “lifting periods” of [1-5, 5-10, 10-20, 20-30 and >30] kg in time intervals [0–0.5, 0.5–1, 1-2, 2-5, 5-10, >10] sec was computed. Back inclination was measured using tri-axial accelerometers. Compared to the other job groups, the operators’ low-back muscles were exposed to more short duration “lifting periods” with varying loads and more frequent medium duration high load “lifting periods” respectively. The operators also worked more with their back inclined (>30° >60° and >90°) than the remaining job groups. Nonetheless, more than 41% of the workers performed heavy “lifting periods” that exceeded Danish lifting guidelines. This EVA demonstrates that almost half of the blue-collar workers were exposed to heavy low-back loading which puts them at risk of developing musculoskeletal disorders and low-back injury. Operators are, in particular, exposed to more short duration and medium duration “lifting periods” with varying load compared to warehouse-, postal- and slaughterhouse workers.
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6.
  • Koch, Markus, et al. (författare)
  • Frequency of breaks, amount of muscular rest, and sustained muscle activity related to neck pain in a pooled dataset
  • 2024
  • Ingår i: PLoS ONE. - 1932-6203. ; 19:6, s. 1-22
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Neck pain remains a persistent challenge in modern society and is frequently encountered across a wide range of occupations, particularly those involving repetitive and monotonous tasks. It might be expected that patterns of trapezius muscle activity at work, characterized by few breaks and prolonged periods of sustained muscle activity, are linked to neck pain. However, previous cross-sectional studies have generally failed to establish a definitive association. While some longitudinal studies have suggested that extended periods of heightened muscle activity could be a risk factor for neck pain, these findings often relied on limited participant numbers or specific professional groups. This study aimed to investigate the relationship between trapezius muscle activity and neck pain by pooling data from seven Scandinavian research institutes encompassing a diverse range of occupational backgrounds.METHODS: Electromyographic (EMG) data for the upper trapezius muscle, collected during working hours, were coupled with questionnaire responses pertaining to neck pain, individual characteristics, and potential confounding variables for a total of 731 subjects. Additionally, longitudinal data from 258 subjects were available. The various EMG datasets were consolidated into a standardized format, and efforts were made to harmonize inquiries about neck pain. Regression analyses, adjusting for sex and height, were conducted to explore the associations between muscle activity variables and neck pain. An exposure index was devised to quantify the cumulative neck load experienced during working hours and to differentiate between various occupational categories.RESULTS: The cross-sectional data displayed a distinct pattern characterized by positive associations for brief periods of sustained muscle activity (SUMA) and negative associations for prolonged SUMA-periods and neck pain. The longitudinal data exhibited a contrasting trend, although it was not as pronounced as the cross-sectional findings. When employing the exposure index, notable differences in cumulative muscle load emerged among occupational groups, and positive associations with longitudinal neck pain were identified.DISCUSSION: The results suggest that individuals with neck pain experience higher cumulative workloads and extended periods of muscle activity over the long term. In the short term, they appear to compensate by taking frequent short breaks, resulting in a lower cumulative workload. Regardless of their occupation, it is crucial to distribute work breaks throughout the workday to ensure that the cumulative load remains manageable.
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7.
  • Sundstrup, Emil, et al. (författare)
  • Central Sensitization and Perceived Indoor Climate among Workers with Chronic Upper-Limb Pain: Cross-Sectional Study.
  • 2015
  • Ingår i: Pain Research and Treatment. - : Hindawi Limited. - 2090-1542 .- 2090-1550. ; 2015, s. 793750-793750
  • Tidskriftsartikel (refereegranskat)abstract
    • Monitoring of indoor climate is an essential part of occupational health and safety. While questionnaires are commonly used for surveillance, not all workers may perceive an identical indoor climate similarly. The aim of this study was to evaluate perceived indoor climate among workers with chronic pain compared with pain-free colleagues and to determine the influence of central sensitization on this perception. Eighty-two male slaughterhouse workers, 49 with upper-limb chronic pain and 33 pain-free controls, replied to a questionnaire with 13 items of indoor climate complaints. Pressure pain threshold (PPT) was measured in muscles of the arm, shoulder, and lower leg. Cross-sectional associations were determined using general linear models controlled for age, smoking, and job position. The number of indoor climate complaints was twice as high among workers with chronic pain compared with pain-free controls (1.8 [95% CI: 1.3-2.3] versus 0.9 [0.4-1.5], resp.). PPT of the nonpainful leg muscle was negatively associated with the number of complaints. Workers with chronic pain reported more indoor climate complaints than pain-free controls despite similar actual indoor climate. Previous studies that did not account for musculoskeletal pain in questionnaire assessment of indoor climate may be biased. Central sensitization likely explains the present findings.
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