| 1. |
- Carlsson, Pernilla, et al.
(författare)
-
Polychlorinated biphenyls (PCBs) as sentinels for the elucidation of Arctic environmental change processes : a comprehensive review combined with ArcRisk project results
- 2018
-
Ingår i: Environmental Science and Pollution Research. - : Springer Science and Business Media LLC. - 0944-1344 .- 1614-7499. ; 25:23, s. 22499-22528
-
Forskningsöversikt (refereegranskat)abstract
- Polychlorinated biphenyls (PCBs) can be used as chemical sentinels for the assessment of anthropogenic influences on Arctic environmental change. We present an overview of studies on PCBs in the Arctic and combine these with the findings from ArcRisk-a major European Union-funded project aimed at examining the effects of climate change on the transport of contaminants to and their behaviour of in the Arctic-to provide a case study on the behaviour and impact of PCBs over time in the Arctic. PCBs in the Arctic have shown declining trends in the environment over the last few decades. Atmospheric long-range transport from secondary and primary sources is the major input of PCBs to the Arctic region. Modelling of the atmospheric PCB composition and behaviour showed some increases in environmental concentrations in a warmer Arctic, but the general decline in PCB levels is still the most prominent feature. 'Within-Arctic' processing of PCBs will be affected by climate change-related processes such as changing wet deposition. These in turn will influence biological exposure and uptake of PCBs. The pan-Arctic rivers draining large Arctic/sub-Arctic catchments provide a significant source of PCBs to the Arctic Ocean, although changes in hydrology/sediment transport combined with a changing marine environment remain areas of uncertainty with regard to PCB fate. Indirect effects of climate change on human exposure, such as a changing diet will influence and possibly reduce PCB exposure for indigenous peoples. Body burdens of PCBs have declined since the 1980s and are predicted to decline further.
|
|
| 2. |
- Eriksson, Daniel, et al.
(författare)
-
GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility
- 2021
-
Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 12:1
-
Tidskriftsartikel (refereegranskat)abstract
- Autoimmune Addison's disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first genome-wide association study on AAD, which identifies nine independent risk loci (P < 5 × 10-8). In addition to loci implicated in lymphocyte function and development shared with other autoimmune diseases such as HLA, BACH2, PTPN22 and CTLA4, we associate two protein-coding alterations in Autoimmune Regulator (AIRE) with AAD. The strongest, p.R471C (rs74203920, OR = 3.4 (2.7-4.3), P = 9.0 × 10-25) introduces an additional cysteine residue in the zinc-finger motif of the second PHD domain of the AIRE protein. This unbiased elucidation of the genetic contribution to development of AAD points to the importance of central immunological tolerance, and explains 35-41% of heritability (h2).
|
|
| 3. |
- Gommenginger, Christine, et al.
(författare)
-
SEASTAR: A mission to study ocean submesoscale dynamics and small-scale atmosphere-ocean processes in coastal, shelf and polar seas
- 2019
-
Ingår i: Frontiers in Marine Science. - : Frontiers Media SA. - 2296-7745. ; 6:JUL
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- High-resolution satellite images of ocean color and sea surface temperature reveal an abundance of ocean fronts, vortices and filaments at scales below 10 km but measurements of ocean surface dynamics at these scales are rare. There is increasing recognition of the role played by small scale ocean processes in ocean-atmosphere coupling, upper-ocean mixing and ocean vertical transports, with advanced numerical models and in situ observations highlighting fundamental changes in dynamics when scales reach 1 km. Numerous scientific publications highlight the global impact of small oceanic scales on marine ecosystems, operational forecasts and long-term climate projections through strong ageostrophic circulations, large vertical ocean velocities and mixed layer re-stratification. Small-scale processes particularly dominate in coastal, shelf and polar seas where they mediate important exchanges between land, ocean, atmosphere and the cryosphere e.g. freshwater, pollutants. As numerical models continue to evolve towards finer spatial resolution and increasingly complex coupled atmosphere-wave-ice-ocean systems, modern observing capability lags behind, unable to deliver the high-resolution synoptic measurements of total currents, wind vectors and waves needed to advance understanding, develop better parameterizations and improve model validations, forecasts and projections. SEASTAR is a satellite mission concept that proposes to directly address this critical observational gap with synoptic two-dimensional imaging of total ocean surface current vectors and wind vectors at 1 km resolution and coincident directional wave spectra. Based on major recent advances in squinted along-track Synthetic Aperture Radar interferometry, SEASTAR is an innovative, mature concept with unique demonstrated capabilities, seeking to proceed towards spaceborne implementation within Europe and beyond.
|
|
| 4. |
- Kukkonen, J., et al.
(författare)
-
Towards a Comprehensive Evaluation of the Environmental and Health Impacts of Shipping Emissions
- 2022
-
Ingår i: Springer Proceedings in Complexity. - Cham : Springer International Publishing. - 2213-8684 .- 2213-8692. ; , s. 329-336
-
Konferensbidrag (refereegranskat)abstract
- We present a new concept for marine research, applied in the EU-funded project EMERGE, “Evaluation, control and Mitigation of the EnviRonmental impacts of shippinG Emissions” (2020–2024; https://emerge-h2020.eu/ ). For the first time, both the various marine and atmospheric impacts of the shipping sector have been and will be comprehensively analyzed, using a concerted modelling and measurements framework. The experimental part of the project focuses on five European geographical case studies in different ecologically vulnerable regions, and a mobile onboard case study. The EMERGE consortium has also developed a harmonised and integrated modelling framework to assess the combined impacts of shipping emissions, both (i) on the marine ecosystems and (ii) the atmospheric environment. The first results include substantial refinements of a range of models to be applied, especially those for the STEAM and OpenDrift models. In particular, the STEAM (Ship Traffic Emission Assessment Model) model has been extended to allow for the effects of atmospheric and oceanographic factors on the fuel consumption and emissions of the ships. The OpenDrift model has been improved to take into account the partitioning, degradation, and volatilization of pollutants in water. The predicted emission and discharge values have been used as input for both regional scale atmospheric dispersion models, such as WRF-CMAQ (Weather Research and Forecasting—Community Multiscale Air Quality Model) and SILAM (System for Integrated modeLling of Atmospheric composition), and water quality and circulation models, such as OpenDrift (Open source model for the drifting of substances in the ocean) and Delft3D (oceanographic model). The case study regions are Eastern Mediterranean, Northern Adriatic Sea, the Lagoon of Aveiro, the Solent Strait and the Öresund Strait. We have also conducted a substantial part of the experimental campaigns scheduled in the project. The final assessment will include the benefits and costs of control and mitigation options affecting water quality, air pollution exposure, health impacts, climate forcing, and ecotoxicological effects and bioaccumulation of pollutants in marine biota.
|
|
| 5. |
- Wu, Lichuan, et al.
(författare)
-
Ocean‐Wave‐Atmosphere Interaction Processes in a Fully Coupled Modeling System
- 2019
-
Ingår i: Journal of Advances in Modeling Earth Systems. - 1942-2466. ; 11:11, s. 3852-3874
-
Tidskriftsartikel (refereegranskat)abstract
- A high‐resolution coupled ocean‐wave‐atmosphere model (Uppsala University Coupled model, UU‐CM) of the Baltic Sea and the North Sea with improved representation of ocean‐wave‐atmosphere interaction processes is presented. In the UU‐CM model, the stress on the air‐sea interface is estimated as a balance of four stress terms, that is, the air‐side stress, ocean‐side stress, wave‐supported stress (absorption of momentum by the wave field), and the momentum flux from waves to currents (breaking waves). The vector differences between these four stress terms are considered in the coupled system. The turbulent kinetic energy flux induced by wave breaking, the Stokes‐Coriolis force and the Stokes drift material advection terms are added to the ocean circulation model component. Based on two‐month‐long (January and July) simulations, we find that the ocean‐wave‐atmosphere coupling has a significant influence on coastal areas. The coupled system captures the influence of surface currents and local systems such as coastal upwelling and their impact on the atmosphere. The wave‐current interaction enhances the upper ocean mixing and reduces the sea surface temperature in July significantly. However, the pattern of the wave‐current processes influences on the ocean current and waves are complex due to the stress differences in both magnitude and direction.
|
|
| 6. |
- Wu, Lichuan, et al.
(författare)
-
The Redistribution of Air-€“Sea Momentum and Turbulent Kinetic Energy Fluxes by Ocean Surface Gravity Waves
- 2022
-
Ingår i: Journal of Physical Oceanography. - : American Meteorological Society. ; 52:7, s. 1483-1496
-
Tidskriftsartikel (refereegranskat)abstract
- The momentum flux to the ocean interior is commonly assumed to be identical to the momentum flux lost from the atmosphere in traditional atmosphere, ocean, and coupled models. However, ocean surface gravity waves (hereafter waves) can alter the magnitude and direction of the ocean-side stress (tau(oc)) from the air-side stress (tau(a)). This is rarely considered in coupled climate and forecast models. Based on a 30-yr wave hindcast, the redistribution of the global wind stress and turbulent kinetic energy (TKE) flux by waves was investigated. Waves play a more important role in the windy oceans in middle and high latitudes than that in the oceans in the tropics (i.e., the central portion of the Pacific and Atlantic Oceans). On average, the relative difference between tau(oc) and tau(a), gamma(tau), can be up to 6% in middle and high latitudes. The frequency of occurrence of gamma(tau) > 9% can be up to 10% in the windy extratropics. The directional difference between tau(oc) and tau(a) exceeds 3.5 degrees in the middle and high latitudes 10% of the time. The difference between tau(oc) and tau(a) becomes more significant closer to the coasts of the continents due to strong wind gradients. The friction velocity-based approach overestimates (underestimates) the breaking-induced TKE flux in the tropics (middle and high latitudes). The findings presented in the current study show that coupled climate and Earth system models would clearly benefit from the inclusion of a wave model. Significance StatementThe purpose of this study is to investigate the redistribution of the global wind stress and turbulent kinetic energy flux due to surface waves based on a 30-yr wave hindcast. The mean relative difference of the magnitude between the air-side and ocean-side stress is up to 6% with a 90th percentile of more than 9% in the windy extratropics. Due to strong wind gradients, the redistributive role of waves in the stress becomes more significant closer to coasts. The results indicate that we should consider the redistributive role of waves in the momentum and energy fluxes in climate and Earth system models since they are the key elements in the predictability of weather forecasting models and climate models.
|
|
