| 1. |
- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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| 2. |
- Ruilope, LM, et al.
(författare)
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Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial
- 2019
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Ingår i: American journal of nephrology. - : S. Karger AG. - 1421-9670 .- 0250-8095. ; 50:5, s. 345-356
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Tidskriftsartikel (refereegranskat)abstract
- <b><i>Background:</i></b> Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. <b><i>Patients and</i></b> <b><i>Methods:</i></b> The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate ≥25 mL/min/1.73 m<sup>2</sup> and albuminuria (urinary albumin-to-creatinine ratio ≥30 to ≤5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. <b><i>Conclusions:</i></b> FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049.
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| 3. |
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| 4. |
- Abbasi, R., et al.
(författare)
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Characterization of the astrophysical diffuse neutrino flux using starting track events in IceCube
- 2024
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Ingår i: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 2470-0010 .- 2470-0029. ; 110:2
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Tidskriftsartikel (refereegranskat)abstract
- A measurement of the diffuse astrophysical neutrino spectrum is presented using IceCube data collected from 2011-2022 (10.3 years). We developed novel detection techniques to search for events with a contained vertex and exiting track induced by muon neutrinos undergoing a charged-current interaction. Searching for these starting track events allows us to not only more effectively reject atmospheric muons but also atmospheric neutrino backgrounds in the southern sky, opening a new window to the sub-100 TeV astrophysical neutrino sky. The event selection is constructed using a dynamic starting track veto and machine learning algorithms. We use this data to measure the astrophysical diffuse flux as a single power law flux (SPL) with a best-fit spectral index of γ=2.58-0.09+0.10 and per-flavor normalization of φper-flavorAstro=1.68-0.22+0.19×10-18×GeV-1 cm-2 s-1 sr-1 (at 100 TeV). The sensitive energy range for this dataset is 3-550 TeV under the SPL assumption. This data was also used to measure the flux under a broken power law, however we did not find any evidence of a low energy cutoff.
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| 5. |
- Abbasi, R., et al.
(författare)
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Improved modeling of in-ice particle showers for IceCube event reconstruction
- 2024
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Ingår i: Journal of Instrumentation. - 1748-0221. ; 19:6
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Tidskriftsartikel (refereegranskat)abstract
- The IceCube Neutrino Observatory relies on an array of photomultiplier tubes to detect Cherenkov light produced by charged particles in the South Pole ice. IceCube data analyses depend on an in-depth characterization of the glacial ice, and on novel approaches in event reconstruction that utilize fast approximations of photoelectron yields. Here, a more accurate model is derived for event reconstruction that better captures our current knowledge of ice optical properties. When evaluated on a Monte Carlo simulation set, the median angular resolution for in-ice particle showers improves by over a factor of three compared to a reconstruction based on a simplified model of the ice. The most substantial improvement is obtained when including effects of birefringence due to the polycrystalline structure of the ice. When evaluated on data classified as particle showers in the high-energy starting events sample, a significantly improved description of the events is observed.
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| 6. |
- Abbasi, R., et al.
(författare)
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Citizen science for IceCube: Name that Neutrino
- 2024
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Ingår i: European Physical Journal Plus. - 2190-5444. ; 139:6
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Tidskriftsartikel (refereegranskat)abstract
- Name that Neutrino is a citizen science project where volunteers aid in classification of events for the IceCube Neutrino Observatory, an immense particle detector at the geographic South Pole. From March 2023 to September 2023, volunteers did classifications of videos produced from simulated data of both neutrino signal and background interactions. Name that Neutrino obtained more than 128,000 classifications by over 1800 registered volunteers that were compared to results obtained by a deep neural network machine-learning algorithm. Possible improvements for both Name that Neutrino and the deep neural network are discussed.
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| 7. |
- Barnett, R., et al.
(författare)
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Euclid preparation V. Predicted yield of redshift 7 < z < 9 quasars from the wide survey
- 2019
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 631
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Tidskriftsartikel (refereegranskat)abstract
- We provide predictions of the yield of 7 < z < 9 quasars from the Euclid wide survey, updating the calculation presented in the Euclid Red Book in several ways. We account for revisions to the Euclid near-infrared filter wavelengths; we adopt steeper rates of decline of the quasar luminosity function (QLF; Phi) with redshift, Phi proportional to 10(k(z-6)), k = 0:72, and a further steeper rate of decline, k = 0:92; we use better models of the contaminating populations (MLT dwarfs and compact early-type galaxies); and we make use of an improved Bayesian selection method, compared to the colour cuts used for the Red Book calculation, allowing the identification of fainter quasars, down to J(AB) similar to 23. Quasars at z > 8 may be selected from Euclid OYJH photometry alone, but selection over the redshift interval 7 < z < 8 is greatly improved by the addition of z-band data from, e.g., Pan-STARRS and LSST. We calculate predicted quasar yields for the assumed values of the rate of decline of the QLF beyond z = 6. If the decline of the QLF accelerates beyond z = 6, with k = 0.92, Euclid should nevertheless find over 100 quasars with 7.0 < z < 7.5, and similar to 25 quasars beyond the current record of z = 7.5, including similar to 8 beyond z = 8.0. The first Euclid quasars at z > 7.5 should be found in the DR1 data release, expected in 2024. It will be possible to determine the bright-end slope of the QLF, 7 < z < 8, M-1450 < 25, using 8m class telescopes to confirm candidates, but follow-up with JWST or E-ELT will be required to measure the faint-end slope. Contamination of the candidate lists is predicted to be modest even at J(AB) similar to 23. The precision with which k can be determined over 7 < z < 8 depends on the value of k, but assuming k = 0.72 it can be measured to a 1 sigma uncertainty of 0.07.
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| 8. |
- Lensink, Marc F., et al.
(författare)
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15-CAPRI experiment
- 2023
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Ingår i: Proteins. - : WILEY. - 0887-3585 .- 1097-0134.
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Tidskriftsartikel (refereegranskat)abstract
- We present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody-antigen complexes, and 7 large assemblies. On average similar to 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups and by 15 CAPRI scorer groups were evaluated using the CAPRI model quality measures and the DockQ score consolidating these measures. The prediction performance was quantified by a weighted score based on the number of models of acceptable quality or higher submitted by each group among their five best models. Results show substantial progress achieved across a significant fraction of the 60+ participating groups. High-quality models were produced for about 40% of the targets compared to 8% two years earlier. This remarkable improvement is due to the wide use of the AlphaFold2 and AlphaFold2-Multimer software and the confidence metrics they provide. Notably, expanded sampling of candidate solutions by manipulating these deep learning inference engines, enriching multiple sequence alignments, or integration of advanced modeling tools, enabled top performing groups to exceed the performance of a standard AlphaFold2-Multimer version used as a yard stick. This notwithstanding, performance remained poor for complexes with antibodies and nanobodies, where evolutionary relationships between the binding partners are lacking, and for complexes featuring conformational flexibility, clearly indicating that the prediction of protein complexes remains a challenging problem.
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| 9. |
- Carpio, A. J., et al.
(författare)
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Angling as a source of non-native freshwater fish : a European review
- 2019
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Ingår i: Biological Invasions. - : Springer Science and Business Media LLC. - 1387-3547 .- 1573-1464. ; 21:11, s. 3233-3248
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Tidskriftsartikel (refereegranskat)abstract
- In a context of the growing concern about the impact of biological invasions, our objective is to review the role of those non-native species that have primarily been introduced for angling purposes in at least one European country. We are particularly interested in: (1) the relative role of sport fish species in the context of non-native species introductions; (2) assessing the relative importance of different fish taxa; (3) identifying similarity patterns in the composition of the angling fish species introduced throughout the continent, and (4) assessing the underlying factors that drive their diversity in Europe. According to our results, 23.6% of the freshwater fish introduced into Europe during the last century were released primarily for angling purposes. The species composition differed among countries, with a higher diversity of introduced angling species in larger countries and in those with a greater GDP per capita, along with a lower latitude. This review stresses that angling was a significant pathway for the introduction of invasive fish species into Europe in the last century. Furthermore, some of the introduced angling species had severe environmental impacts on many European regions. However, introductions of non-native angling species are still occurring. Therefore, existing EU regulations need better enforcement as well as to increase public awareness regarding invasive fish. This will help to preserve biodiversity and improve the sustainability of current angling schemes in increasingly managed European freshwater ecosystems. However, non-native fish could make angling sustainable, although not for biodiversity generally.
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| 10. |
- Gonzalez-Alfonso, E., et al.
(författare)
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HIGH-LYING OH ABSORPTION, [C II] DEFICITS, AND EXTREME LFIR/MH2 RATIOS IN GALAXIES
- 2015
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Ingår i: Astrophysical Journal. - 1538-4357 .- 0004-637X. ; 800:1, s. 1-10
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Tidskriftsartikel (refereegranskat)abstract
- Herschel/PACS observations of 29 local (ultra) luminous infrared galaxies, including both starburst and active galactic nucleus (AGN) dominated sources as diagnosed in the mid-infrared/optical, show that the equivalent width of the absorbing OH 65 mu m.3/2 J = 9/2-7/2 line (Weq(OH65)) with lower level energy Elow 300 K, is anticorrelated with the [Cii] 158 mu m line to far-infrared luminosity ratio, and correlated with the far-infrared luminosity per unit gas mass and with the 60-to-100 mu m far-infrared color. While all sources are in the active LIR/MH2 > 50L /M mode as derived from previous CO line studies, the OH65 absorption shows a bimodal distribution with a discontinuity at LFIR/MH2 100L /M . In the most buried sources, OH65 probes material partially responsible for the silicate 9.7 mu m absorption. Combined with observations of the OH 71 mu m.1/2 J = 7/2-5/2 doublet (Elow 415 K), radiative transfer models characterized by the equivalent dust temperature, Tdust, and the continuum optical depth at 100 mu m, t100, indicate that strong [C ii] 158 mu m deficits are associated with far-IR thick (t100 0.7, NH 1024 cm-2), warm (Tdust 60 K) structures where the OH 65 mu m absorption is produced, most likely in circumnuclear disks/tori/cocoons. With their high LFIR/MH2 ratios and columns, the presence of these structures is expected to give rise to strong [C ii] deficits. Weq(OH65) probes the fraction of infrared luminosity arising from these compact/warm environments, which is 30%-50% in sources with high Weq(OH65). Sources with high Weq(OH65) have surface densities of both LIR and MH2 higher than inferred from the half-light (CO or UV/optical) radius, tracing coherent structures that represent the most buried/active stage of (circum) nuclear starburst-AGN co-evolution.
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| 11. |
- Lutz, D., et al.
(författare)
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Molecular outflows in local galaxies: Method comparison and a role of intermittent AGN driving
- 2020
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 633
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Tidskriftsartikel (refereegranskat)abstract
- We report new detections and limits from a NOEMA and ALMA CO(1-0) search for molecular outflows in 13 local galaxies with high far-infrared surface brightness, and combine these with local universe CO outflow results from the literature. The CO line ratios and spatial outflow structure of our targets provide some constraints on the conversion steps from observables to physical quantities such as molecular mass outflow rates. Where available, ratios between outflow emission in higher J CO transitions and in CO(1-0) are typically consistent with excitation R-i1 less than or similar to 1. However, for IRAS 13120 5453, R-31 = 2.10 +/- 0.29 indicates optically thin CO in the outflow. Like much of the outflow literature, we use ff CO(1 0) = 0.8, and we present arguments for using C = 1 in deriving molecular mass outflow rates. (M)over dot(out) = CM(out)v(out)/R-out. We compare the two main methods for molecular outflow detection: CO millimeter interferometry and Herschel OH-based spectroscopic outflow searches. For 26 sources studied with both methods, we find an 80% agreement in detecting vout & 150 km s 1 outflows, and non-matches can be plausibly ascribed to outflow geometry and signal-to-noise ratio. For a published sample of 12 bright ultraluminous infrared galaxies with detailed OH-based outflow modeling, CO outflows are detected in all but one. Outflow masses, velocities, and sizes for these 11 sources agree well between the two methods, and modest remaining di fferences may relate to the di fferent but overlapping regions sampled by CO emission and OH absorption. Outflow properties correlate better with active galactic nucleus (AGN) luminosity and with bolometric luminosity than with far-infrared surface brightness. The most massive outflows are found for systems with current AGN activity, but significant outflows in nonAGN systems must relate to star formation or to AGN activity in the recent past. We report scaling relations for the increase of outflow mass, rate, momentum rate, and kinetic power with bolometric luminosity. Short flow times of similar to 10(6) yr and some sources with resolved multiple outflow episodes support a role of intermittent driving, likely by AGNs.
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| 12. |
- Cicone, C., et al.
(författare)
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Massive molecular outflows and evidence for AGN feedback from CO observations
- 2014
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 562, s. 25-
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Tidskriftsartikel (refereegranskat)abstract
- We study the properties of massive, galactic-scale outflows of molecular gas and investigate their impact on galaxy evolution. We present new IRAMPdBI CO(1-0) observations of local ultra-luminous infrared galaxies (ULIRGs) and quasar-hosts: a clear signature of massive and energetic molecular outflows, extending on kpc scales, is found in the CO(1-0) kinematics of four out of seven sources, with measured outflow rates of several 100M(circle dot)yr(-1). We combine these new observations with data from the literature, and explore the nature and origin of massive molecular outflows within an extended sample of 19 local galaxies. We find that starburst-dominated galaxies have an outflow rate comparable to their star formation rate (SFR), or even higher by a factor of similar to 2-4, implying that starbursts can indeed be effective in removing cold gas from galaxies. Nevertheless, our results suggest that the presence of an active galactic nucleus (AGN) can boost the outflow rate by a large factor, which is found to increase with the L-AGN/L-bol ratio. The gas depletion time scales due to molecular outflows are anti-correlated with the presence and luminosity of an AGN in these galaxies, and range from a few hundred million years in starburst galaxies down to just a few million years in galaxies hosting powerful AGNs. In quasar hosts, the depletion time scales due to the outflow are much shorter than the depletion time scales due to star formation. We estimate the outflow kinetic power and find that, for galaxies hosting powerful AGNs, it corresponds to about 5% of the AGN luminosity, as expected by models of AGN feedback. Moreover, we find that momentum rates of about 20 L-AGN/c are common among the AGN-dominated sources in our sample. For "pure" starburst galaxies, our data tentatively support models in which outflows are mostly momentum-driven by the radiation pressure from young stars onto dusty clouds. Overall, our results indicate that, although starbursts are effective in powering massive molecular outflows, the presence of an AGN may strongly enhance such outflows, and therefore have a profound feedback effect on the evolution of galaxies by efficiently removing fuel for star formation, hence quenching star formation.
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| 13. |
- Gonzalez-Alfonso, E., et al.
(författare)
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Molecular Outflows in Local ULIRGs: Energetics from Multitransition OH Analysis
- 2017
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 1538-4357 .- 0004-637X. ; 836:1
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Tidskriftsartikel (refereegranskat)abstract
- We report on the energetics of molecular outflows in 14 local ultraluminous infrared galaxies (ULIRGs) that show unambiguous outflow signatures (P Cygni profiles or high-velocity absorption wings) in the far-infrared lines of OH measured with the Herschel/PACS spectrometer. All sample galaxies are gas-rich mergers at various stages of the merging process. Detection of both ground-state (at 119 and 79 mu m) and one or more radiatively excited (at 65 and 84 mu m) lines allows us to model the nuclear gas (. 300 pc) and the more extended components using spherically symmetric radiative transfer models. Reliable models and the corresponding energetics are found in 12 of the 14 sources. The highest molecular outflow velocities are found in buried sources, in which slower but massive expansion of the nuclear gas is also observed. With the exception of a few outliers, the outflows have momentum fluxes of (2-5) x L-IR/c and mechanical luminosities of (0.1-0.3)% of L-IR. The moderate momentum boosts in these sources (. 3) suggest that the outflows are mostly momentum driven by the combined effects of active galactic nuclei (AGNs) and nuclear starbursts, as a result of radiation pressure, winds, and supernova remnants. In some sources ( similar to 20%), however, powerful (10(10.5- 11) L circle dot) AGN feedback and (partially) energy-conserving phases are required, with momentum boosts in the range of 3-20. These outflows appear to be stochastic, strong AGN feedback events that occur throughout the merging process. In a few sources, the outflow activity in the innermost regions has subsided in the past similar to 1 Myr. While OH traces the molecular outflows at subkiloparsec scales, comparison of the masses traced by OH with those previously inferred from tracers of more extended outflowing gas suggests that most mass is loaded (with loading factors of M/SFR = 1-10) from the central galactic cores (a few. x. 100 pc), qualitatively consistent with an ongoing inside-out quenching of star formation. Outflow depletion timescales are
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| 14. |
- Gonzalez-Alfonso, E., et al.
(författare)
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The Mrk 231 molecular outflow as seen in OH
- 2014
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 561, s. Article no. A27-
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Tidskriftsartikel (refereegranskat)abstract
- We report on the Herschel/PACS observations of OH in Mrk 231, with detections in nine doublets observed within the PACS range, and present radiative-transfer models for the outflowing OH. Clear signatures of outflowing gas are found in up to six OH doublets with different excitation requirements. At least two outflowing components are identified, one with OH radiatively excited, and the other with low excitation, presumably spatially extended and roughly spherical. Particularly prominent, the blue wing of the absorption detected in the in-ladder (2)Pi(3/2) J = 9/2-7/2 OH doublet at 65 mu m, with E-lower = 290 K, indicates that the excited outflowing gas is generated in a compact and warm (circum) nuclear region. Because the excited, outflowing OH gas in Mrk 231 is associated with the warm, far-infrared continuum source, it is most likely more compact (diameter of similar to 200-300 pc) than that probed by CO and HCN. Nevertheless, its mass-outflow rate per unit of solid angle as inferred from OH is similar to that previously derived from CO, greater than or similar to 70 x (2.5 x 10(-6)/X-OH) M-circle dot yr(-1) sr(-1), where X-OH is the OH abundance relative to H nuclei. In spherical symmetry, this would correspond to greater than or similar to 850 x (2.5 x 10(-6)/X-OH) M-circle dot yr(-1), though significant collimation is inferred from the line profiles. The momentum flux of the excited component attains similar to 15 L-AGN/c, with an OH column density of (1.5-3) x 10(17) cm(-2) and a mechanical luminosity of similar to 10(11) L-circle dot. In addition, the detection of very excited, radiatively pumped OH peaking at central velocities indicates the presence of a nuclear reservoir of gas rich in OH, plausibly the 130 pc scale circumnuclear torus previously detected in OH megamaser emission, that may be feeding the outflow. An exceptional (OH)-O-18 enhancement, with OH/(OH)-O-18 less than or similar to 30 at both central and blueshifted velocities, is most likely the result of interstellar-medium processing by recent starburst and supernova activity within the circumnuclear torus or thick disk.
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| 15. |
- Waldman, Meryl, et al.
(författare)
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COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International Registry
- 2022
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Ingår i: KIDNEY360. - : AMER SOC NEPHROLOGY. - 2641-7650. ; 3:2, s. 293-306
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Tidskriftsartikel (refereegranskat)abstract
- Background The acute and long-term effects of severe acute respiratory syndrome coronavirus 2 infection in individuals with GN are still unclear. To address this relevant issue, we created the International Registry of COVID-19 infection in GN.Methods We collected serial information on kidney-related and-unrelated outcomes from 125 GN patients (63 hospitalized and 62 outpatients) and 83 non-GN hospitalized patients with coronavirus disease 2019 (COVID-19) and a median follow-up period of 6.4 (interquartile range 2.3-9.6) months after diagnosis. We used logistic regression for the analyses of clinical outcomes and linear mixed models for the longitudinal analyses of eGFR. All multiple regression models were adjusted for age, sex, ethnicity, and renin-angiotensin-aldosterone system inhibitor use.Results After adjustment for pre-COVID-19 eGFR and other confounders, mortality and AKI did not differ between GN patients and controls (adjusted odds ratio for AKI=1.28; 95% confidence interval [CI], 0.46 to 3.60; P=0.64). The main predictor of AKI was pre-COVID-19 eGFR (adjusted odds ratio per 1 SD unit decrease in eGFR=3.04; 95% CI, 1.76 to 5.28; P,0.001). GN patients developing AKI were less likely to recover pre-COVID19 eGFR compared with controls (adjusted 6-month post-COVID-19 eGFR=0.41; 95% CI, 0.25 to 0.56; times preCOVID-19 eGFR). Shorter duration of GN diagnosis, higher pre-COVID-19 proteinuria, and diagnosis of focal segmental glomerulosclerosis or minimal change disease were associated with a lower post-COVID-19 eGFR.Conclusions Pre-COVID-19 eGFR is the main risk factor for AKI regardless of GN diagnosis. However, GN patients are at higher risk of impaired eGFR recovery after COVID-19-associated AKI. These patients (especially those with high baseline proteinuria or a diagnosis of focal segmental glomerulosclerosis or minimal change disease) should be closely monitored not only during the acute phases of COVID-19 but also after its resolution.
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| 16. |
- Carpio, Antonio J., et al.
(författare)
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Effects of wild boar predation on nests of wading birds in various Swedish habitats
- 2016
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Ingår i: European Journal of Wildlife Research. - : Springer Science and Business Media LLC. - 1612-4642 .- 1439-0574. ; 62:4, s. 423-430
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Tidskriftsartikel (refereegranskat)abstract
- The wild boar has, over the past few decades, undergone an expansion in Europe, which may have negatively affected ground-nesting bird populations and particularly those of wading birds. The aim of this study was to evaluate predation on waders’ nests by wild boar in Sweden, where this species has been increasing since its reintroduction. This was done by placing artificial nests in seven different study areas. A comparison was then made of predation rates of the nests placed on control plots (areas in which no wild boar were present but other predators were) and plots containing different abundances of wild boar. Contrary to our expectations, the proportion of nests predated was significantly lower in those areas in which wild boar were present, with a predation rate of 54 %, whereas the predation rate was 87.5 % in the others. The wild boar was identified as the second most important nest predator in the plots in which it was present, accounting for 18 % of the predated nests. The main predator on both types of plots was the red fox, which was responsible for 28 and 38.5 % of the predated nests on plots with/without wild boar, respectively. Interestingly, predation by badgers occurred principally in areas in which the wild boar was absent (34.5 % of the predated nests), whereas only one nest was predated by this predator in areas containing wild boar. It is not, however, possible to state whether predation by badgers was lower because of the presence of wild boar or whether this was owing to the fact that badgers do not select those particular patches because of habitat features.
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| 17. |
- Carpio, Antonio J., et al.
(författare)
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Hunting as a source of alien species : a European review
- 2017
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Ingår i: Biological Invasions. - : Springer Science and Business Media LLC. - 1387-3547 .- 1573-1464. ; 19:4, s. 1197-1211
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Tidskriftsartikel (refereegranskat)abstract
- Hunting activities are responsible for the translocation and restocking of millions of animals throughout Europe, including the introduction of alien species. In a context of the growing use of game translocations and of increasing concern about the impact of biological invasions, our goal is to review the role of alien species introduced primarily for hunting purposes on the European scale. In particular, we explore: (1) the relative importance of game species in the context of alien species introductions; (2) the temporal evolution of the number of species introduced for hunting purposes; (3) the contribution of different taxa; (4) the pattern of introduced game species composition across countries (in terms of similarity), and (5) the underlying human demographic factors driving the diversity of introduced game species per country. According to our results, 24.3% of the mammals and 30.2% of the birds introduced into Europe during the last century were released primarily for hunting purposes, in total, 93 species (63 birds and 36 mammals), the most important taxa being Artiodactyls, Anseriformes and Galliformes. The species composition differed among countries, with a higher diversity of introduced game species in larger countries and in those with a higher human population density and proportion of hunters. This review stresses that hunting was a significant pathway for the introduction of invasive species into Europe in the last century. Since some of the game species introduced have had severe environmental impacts on many European regions, and introductions of non-native game species are still occurring, it is essential to improve regulations and increase public awareness regarding invasive game animals. This will help to preserve biodiversity and improve the sustainability of current hunting schemes in increasingly managed European ecosystems.
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| 18. |
- Carpio, Antonio J., et al.
(författare)
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Wild boar effects on fungal abundance and guilds from sporocarp sampling in a boreal forest ecosystem
- 2022
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Ingår i: Animals. - : MDPI. - 2076-2615. ; 12:19
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Tidskriftsartikel (refereegranskat)abstract
- Native wild boar (Sus scrofa) populations are expanding across Europe. This is cause for concern in some areas where overabundant populations impact natural ecosystems and adjacent agronomic systems. To better manage the potential for impacts, managers require more information about how the species may affect other organisms. For example, information regarding the effect of wild boar on soil fungi for management application is lacking. Soil fungi play a fundamental role in ecosystems, driving essential ecological functions; acting as mycorrhizal symbionts, sustaining plant nutrition and providing defense; as saprotrophs, regulating the organic matter decomposition; or as plant pathogens, regulating plant fitness and survival. During autumn (Sep–Nov) 2018, we investigated the effects of wild boar (presence/absence and rooting intensity) on the abundance (number of individuals) of fungal sporocarps and their functional guilds (symbiotic, saprotrophic and pathogenic). We selected eleven forested sites (400–500 × 150–200 m) in central Sweden; six with and five without the presence of wild boar. Within each forest, we selected one transect (200 m long), and five plots (2 × 2 m each) for sites without wild boar, and ten plots for sites with boars (five within and five outside wild boar disturbances), to determine the relationship between the intensity of rooting and the abundance of sporocarps for three fungal guilds. We found that the presence of wild boar and rooting intensity were associated with the abundance of sporocarps. Interestingly, this relationship varied depending on the fungal guild analyzed, where wild boar rooting had a positive correlation with saprophytic sporocarps and a negative correlation with symbiotic sporocarps. Pathogenic fungi, in turn, were more abundant in undisturbed plots (no rooting) but located in areas with the presence of wild boar. Our results indicate that wild boar activities can potentially regulate the abundance of fungal sporocarps, with different impacts on fungal guilds. Therefore, wild boar can affect many essential ecosystem functions driven by soil fungi in boreal forests, such as positive effects on energy rotation and in creating mineral availability to plants, which could lead to increased diversity of plants in boreal forests.
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| 19. |
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| 20. |
- Guerrero-Casado, José, et al.
(författare)
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Assessment of the suitability of latrine counts as an indirect method by which to estimate the abundance of European rabbit populations at high and low abundance
- 2020
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Ingår i: European Journal of Wildlife Research. - : Springer Science and Business Media LLC. - 1612-4642 .- 1439-0574. ; 66:1
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Tidskriftsartikel (refereegranskat)abstract
- Monitoring European rabbit (Oryctolagus cuniculus) populations using suitable methods is crucial, especially in those areas in which endangered predators remain and rabbits occur at low densities. We first counted the number of rabbits, the number of scattered pellets, and the number of latrines counted within 16 plots established in areas of low rabbit density, showing that the number of rabbits counted inside the plots was more closely correlated with the number of pellets counted than with the number of latrines. In addition, no latrines were found in 8 plots. In 53 walking transects, the number of pellets m−2 and the number of latrines km−1 had a positive relationship, but no significant correlation was obtained between the two methods when only the transects with a low rabbit abundance were selected. These results suggest that although counting latrines can be useful to compare areas with different abundances, it may underestimate rabbit abundance at low abundances where counting scattered pellets is, therefore, the most accurate alternative. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
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- Scheffler, Julia M., et al.
(författare)
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ER alpha Signaling in a Subset of CXCL12-Abundant Reticular Cells Regulates Trabecular Bone in Mice
- 2022
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Ingår i: JBMR Plus. - : Wiley. - 2473-4039. ; 6:8
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Tidskriftsartikel (refereegranskat)abstract
- Estrogen has pronounced effects on the immune system, which also influences bone homeostasis. In recent years, stromal cells in lymphoid organs have gained increasing attention as they not only support the regulation of immune responses but also affect bone remodeling. A conditional knockout mouse model where estrogen receptor alpha (ER alpha) is deleted in CCL19-expressing stromal cells (Ccl19-Cre ER alpha(fl/fl) mice) was generated and bone densitometry was performed to analyze the importance of stromal cell-specific ER alpha signaling on the skeleton. Results showed that female Ccl19-Cre ER alpha(fl/fl) mice display reduced total bone mineral density and detailed X-ray analyses revealed that ER alpha expression in CCL19-expressing stromal cells is important for trabecular but not cortical bone homeostasis. Further analysis showed that the trabecular bone loss is caused by increased osteoclastogenesis. Additionally, the bone formation rate was reduced; however, the expression of osteoprogenitor genes was not altered. Analysis of the bone marrow stromal cell compartment revealed a deletion of ER alpha in a subgroup of CXCL12-abundant reticular (CAR) cells resulting in increased secretion of the pro-osteoclastogenic chemokine CXCL12. In conclusion, this study reveals the importance of ER alpha signaling in CAR cells for bone health. (c) 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
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