| 1. |
- Bradnam, K. R., et al.
(författare)
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Assemblathon 2 : Evaluating de novo methods of genome assembly in three vertebrate species
- 2013
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Ingår i: GigaScience. - : BioMed Central (BMC). - 2047-217X. ; 2:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many genome assembly tools are available, but they differ greatly in terms of their performance (speed, scalability, hardware requirements, acceptance of newer read technologies) and in their final output (composition of assembled sequence). More importantly, it remains largely unclear how to best assess the quality of assembled genome sequences. The Assemblathon competitions are intended to assess current state-of-the-art methods in genome assembly. Results: In Assemblathon 2, we provided a variety of sequence data to be assembled for three vertebrate species (a bird, a fish, and snake). This resulted in a total of 43 submitted assemblies from 21 participating teams. We evaluated these assemblies using a combination of optical map data, Fosmid sequences, and several statistical methods. From over 100 different metrics, we chose ten key measures by which to assess the overall quality of the assemblies. Conclusions: Many current genome assemblers produced useful assemblies, containing a significant representation of their genes and overall genome structure. However, the high degree of variability between the entries suggests that there is still much room for improvement in the field of genome assembly and that approaches which work well in assembling the genome of one species may not necessarily work well for another.
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| 2. |
- Chikhi, N., et al.
(författare)
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Evaluation of an effective diameter to study quenching and dry-out of complex debris bed
- 2014
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Ingår i: Annals of Nuclear Energy. - : Elsevier BV. - 0306-4549 .- 1873-2100. ; 74, s. 24-41
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Tidskriftsartikel (refereegranskat)abstract
- Many of the current research works performed in the SARNET-2 WP5 deal with the study of the coolability of debris beds in case of severe nuclear power plant accidents. One of the difficulties for modeling and transposition of experimental results to the real scale and geometry of a debris bed in a reactor is the difficulty to perform experiments with debris beds that are representative for reactor situations. Therefore, many experimental programs have been performed using beds made of multi-diameter spheres or non-spherical particles to study the physical phenomena involved in debris bed coolability and to evaluate an effective diameter. This paper first establishes the ranges of porosity and particle size distribution that might be expected for in-core debris beds and ex-vessel debris beds. Then, the results of pressure drop and dry-out heat flux (DHF) measurements obtained in various experimental setups, POMECO, DEBRIS, COOLOCE/STYX and CALIDE/PRELUDE, are presented. The issues of particle size distribution and non-sphericity are also investigated. It is shown that the experimental data obtained in "simple" debris beds are relevant to describe the behavior of more complex beds. Indeed, for several configurations, it is possible to define an "effective" diameter suitable for evaluating (with the porosity) some model parameters as well as correlations for the pressure drop across the bed, the steam flow rate during quenching and the DHF.
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| 3. |
- Korobeinikov, I, et al.
(författare)
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Surface Tension and Density of Cr–Mn–Ni Steels with Transformation Induced Plasticity Effect
- 2020
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Ingår i: Steel Research International. - : Wiley-VCH Verlag. - 1611-3683 .- 1869-344X.
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Tidskriftsartikel (refereegranskat)abstract
- Thermophysical properties of liquid metal alloys play a crucial role in the variety of processes. Present work reports experimental investigations of two new transformation induced plasticity (TRIP) steels. A classical maximum bubble pressure technique is successfully used to measure surface tension and density of the liquid TRIP-steel samples in the temperatures range of 1500–1800 °C. Experiments are performed in two different measurement cells from TU Freiberg and Commissariat a l'Energie Atomique (CEA), Cadarache. Capillaries are made of zirconia partially stabilized with yttrium oxide, and the samples are molten in Al2O3 crucibles. Measurements are conducted under the argon atmosphere. Surface tension of the investigated samples rises up to 1700 °C and further remains the same. Density of the new steels obtained in this study is in good agreement with the previously reported values for Fe–Cr alloys with similar Cr content. Density of the alloy is estimated as 875 488–11 885 × T (±218.85 kg m−3) for a 15%Cr alloy and 796 042–06 897 × T (±199 kg m−3) for a 19%Cr alloy.
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