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  • Mesas-Sánchez, Laura, et al. (author)
  • Non-enzymatic kinetic resolution of 1,2-azidoalcohols using a planar-chiral DMAP derivative catalyst
  • 2013
  • In: Tetrahedron. - : Elsevier BV. - 0040-4020 .- 1464-5416. ; 69:2, s. 753-757
  • Journal article (peer-reviewed)abstract
    • Optically pure 1,2-azidoalcohols are widely used as precursors for other high value organic products. A non-enzymatic kinetic resolution procedure for the stereoselective synthesis of chiral 1,2-azidoalcohols from the readily available racemic counterparts has been developed, employing a planar-chiral DMAP derivative catalyst. Following this procedure, a range of aromatic 1,2-azidoalcohols was obtained in good selectivities (up to S=45) and high enantiomeric excess (up to 99% ee).
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Dinér, Peter (1)
Mesas-Sánchez, Laura (1)
Díaz-Álvarez, Alba E ... (1)
University
Royal Institute of Technology (1)
Uppsala University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year

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