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| 2. |
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| 3. |
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| 4. |
- Bouyoucef, S E, et al.
(författare)
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Poster Session 2 : Monday 4 May 2015, 08
- 2015
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Tidskriftsartikel (refereegranskat)
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| 5. |
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| 6. |
- Ferreira, Mjv, et al.
(författare)
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Poster Session 3 : Tuesday 5 May 2015, 08
- 2015
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Tidskriftsartikel (refereegranskat)
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| 7. |
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| 8. |
- Ebersole, Charles R., et al.
(författare)
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Many Labs 5: Testing Pre-Data-Collection Peer Review as an Intervention to Increase Replicability
- 2020
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Ingår i: Advances in Methods and Practices in Psychological Science. - : Sage. - 2515-2467 .- 2515-2459. ; 3:3, s. 309-331
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Tidskriftsartikel (refereegranskat)abstract
- Replication studies in psychological science sometimes fail to reproduce prior findings. If these studies use methods that are unfaithful to the original study or ineffective in eliciting the phenomenon of interest, then a failure to replicate may be a failure of the protocol rather than a challenge to the original finding. Formal pre-data-collection peer review by experts may address shortcomings and increase replicability rates. We selected 10 replication studies from the Reproducibility Project: Psychology (RP:P; Open Science Collaboration, 2015) for which the original authors had expressed concerns about the replication designs before data collection; only one of these studies had yielded a statistically significant effect (p < .05). Commenters suggested that lack of adherence to expert review and low-powered tests were the reasons that most of these RP:P studies failed to replicate the original effects. We revised the replication protocols and received formal peer review prior to conducting new replication studies. We administered the RP:P and revised protocols in multiple laboratories (median number of laboratories per original study = 6.5, range = 3-9; median total sample = 1,279.5, range = 276-3,512) for high-powered tests of each original finding with both protocols. Overall, following the preregistered analysis plan, we found that the revised protocols produced effect sizes similar to those of the RP:P protocols (Delta r = .002 or .014, depending on analytic approach). The median effect size for the revised protocols (r = .05) was similar to that of the RP:P protocols (r = .04) and the original RP:P replications (r = .11), and smaller than that of the original studies (r = .37). Analysis of the cumulative evidence across the original studies and the corresponding three replication attempts provided very precise estimates of the 10 tested effects and indicated that their effect sizes (median r = .07, range = .00-.15) were 78% smaller, on average, than the original effect sizes (median r = .37, range = .19-.50).
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| 9. |
- Frantz, Laurent A. F., et al.
(författare)
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Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe
- 2019
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 116:35, s. 17231-17238
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Tidskriftsartikel (refereegranskat)abstract
- Archaeological evidence indicates that pig domestication had begun by similar to 10,500 y before the present ( BP) in the Near East, and mitochondrial DNA ( mtDNA) suggests that pigs arrived in Europe alongside farmers similar to 8,500 y BP. A few thousand years after the introduction of Near Eastern pigs into Europe, however, their characteristic mtDNA signature disappeared and was replaced by haplotypes associated with European wild boars. This turnover could be accounted for by substantial gene flow from local European wild boars, although it is also possible that European wild boars were domesticated independently without any genetic contribution from the Near East. To test these hypotheses, we obtained mtDNA sequences from 2,099 modern and ancient pig samples and 63 nuclear ancient genomes from Near Eastern and European pigs. Our analyses revealed that European domestic pigs dating from 7,100 to 6,000 y BP possessed both Near Eastern and European nuclear ancestry, while later pigs possessed no more than 4% Near Eastern ancestry, indicating that gene flow from European wild boars resulted in a near-complete disappearance of Near East ancestry. In addition, we demonstrate that a variant at a locus encoding black coat color likely originated in the Near East and persisted in European pigs. Altogether, our results indicate that while pigs were not independently domesticated in Europe, the vast majority of human-mediated selection over the past 5,000 y focused on the genomic fraction derived from the European wild boars, and not on the fraction that was selected by early Neolithic farmers over the first 2,500 y of the domestication process.
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| 10. |
- Valassi, E., et al.
(författare)
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High mortality within 90 days of diagnosis in patients with Cushing's syndrome: results from the ERCUSYN registry
- 2019
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Ingår i: European Journal of Endocrinology. - : Oxford University Press (OUP). - 0804-4643 .- 1479-683X. ; 181:5, s. 461-472
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Patients with Cushing's syndrome (CS) have increased mortality. The aim of this study was to evaluate the causes and time of death in a large cohort of patients with CS and to establish factors associated with increased mortality. Methods: In this cohort study, we analyzed 1564 patients included in the European Registry on CS (ERCUSYN); 1045 (67%) had pituitary-dependent CS, 385 (25%) adrenal-dependent CS, 89 (5%) had an ectopic source and 45 (3%) other causes. The median (IQR) overall follow-up time in ERCUSYN was 2.7 (1.2-5.5) years. Results: Forty-nine patients had died at the time of the analysis; 23 (47%) with pituitary-dependent CS, 6 (12%) with adrenal-dependent CS, 18 (37%) with ectopic CS and two (4%) with CS due to other causes. Of 42 patients whose cause of death was known, 15 (36%) died due to progression of the underlying disease, 13 (31%) due to infections, 7 (17%) due to cardiovascular or cerebrovascular disease and 2 due to pulmonary embolism. The commonest cause of death in patients with pituitary-dependent CS and adrenal-dependent CS were infectious diseases (n = 8) and progression of the underlying tumor (n = 10) in patients with ectopic CS. Patients who had died were older and more often males, and had more frequently muscle weakness, diabetes mellitus and ectopic CS, compared to survivors. Of 49 deceased patients, 22 (45%) died within 90 days from start of treatment and 5 (10%) before any treatment was given. The commonest cause of deaths in these 27 patients were infections (n = 10; 37%). In a regression analysis, age, ectopic CS and active disease were independently associated with overall death before and within 90 days from the start of treatment. Conclusion: Mortality rate was highest in patients with ectopic CS. Infectious diseases the commonest cause of death soon after diagnosis, emphasizing the need for careful vigilance at that time, especially in patients presenting with concomitant diabetes mellitus.
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| 11. |
- Albert, Damien, et al.
(författare)
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A Decade with VAMDC : Results and Ambitions
- 2020
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Ingår i: Atoms. - : MDPI. - 2218-2004. ; 8:4
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents an overview of the current status of the Virtual Atomic and Molecular Data Centre (VAMDC) e-infrastructure, including the current status of the VAMDC-connected (or to be connected) databases, updates on the latest technological development within the infrastructure and a presentation of some application tools that make use of the VAMDC e-infrastructure. We analyse the past 10 years of VAMDC development and operation, and assess their impact both on the field of atomic and molecular (A&M) physics itself and on heterogeneous data management in international cooperation. The highly sophisticated VAMDC infrastructure and the related databases developed over this long term make them a perfect resource of sustainable data for future applications in many fields of research. However, we also discuss the current limitations that prevent VAMDC from becoming the main publishing platform and the main source of A&M data for user communities, and present possible solutions under investigation by the consortium. Several user application examples are presented, illustrating the benefits of VAMDC in current research applications, which often need the A&M data from more than one database. Finally, we present our vision for the future of VAMDC.
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| 12. |
- Arvidsson, Anna K, 1971-, et al.
(författare)
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Appraisal methodology : Deliverable D2.1
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This report represents INFRACOMS deliverable D2.1 Appraisal Methodology. It builds upon the deliverables of INFRACOMS Work Package 1 which identified the information needs, gaps and priorities of NRAs in terms of their approach to data collection and monitoring, and a list of current and emerging measurement technologies. This report includes a review of several commonly-used appraisal methodologies that can be used to evaluate the effectiveness, suitability and potential impact of new technologies for an organisation. These methodologies include Technology Readiness Levels (TRLs), Cost Benefit Analysis (CBA), Life Cycle Cost Analysis (LCCA), Risk Assessment, and Multi-Criteria Decision Analysis (MCDA). Elements of these commonly used methodologies are included in the INFRACOMS Appraisal Methodology. The report also includes key highlights from a workshop with NRAs conducted in January 2023 which also fed into the design of the appraisal methodology. The INFRACOMS Appraisal Methodology described here is designed around the technology use case, that is, a particular application of a technology by a NRA. It incorporates three core processes for Pre-Evaluation, Evaluation and Case Studies of technology use cases. It also includes processes for NRAs to define their strategic and technical priorities so that the appraisal process can be tailored to addressing their individual requirements, as identified from Work Package 1.
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| 13. |
- Arvidsson, Anna K, 1971-, et al.
(författare)
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Current Practice, Future need and Gap Analysis : Deliverable D1.1
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This report is INFRACOMS first deliverable D1.1. It addresses the “Understanding of information needs and gaps” component of the project. The aim has been to identify the current priorities and future needs of NRAs for the management of carriageway and bridge assets, specifically in terms of their approach to data collection and monitoring. The approach has been to establish existing knowledge via a review of previous projects, current best practices and standards in data collection and inspection, and a review of current business processes, NRA strategies around data collection and digitalisation etc. The report identifies a set of key imperatives for carriageway and bridge assets covering Availability, Reliability, Environment, Economy and Safety. Each of these is supported by the collection of key condition data, which is used to report technical parameters and performance indicators that can be combined to assess the ability of the asset to meet its key imperatives. A wide range of technologies are identified, which are currently applied to collect the data that supports this assessment.The consultation shows that there are also gaps between the desired and the current capability for the assessment of these assets. These include gaps in the data, challenges in the ability to collect the data, gaps in the application of the data that is already collected etc. A review of emerging technologies shows that there are tools and technologies that could help to fill these gaps. These could overcome the limitations of current technologies, better integrate new data sources, provide greater flexibility in using current and new data, and provide better analysis. They include remote sensing, Internet of Things (IoT), crowdsourcing, and advanced data processing/visualisation.
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| 14. |
- Arvidsson, Anna K, 1971-, et al.
(författare)
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Report on state-of-the-art data assessment and visualisation methods : Deliverable D3.1
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Effective analysis and visualisation of data is critical for the efficient application of the data provided by carriageway and bridge condition monitoring technologies. It supports better decisions in relation to asset reliability, availability, safety, economy and environment. This report discusses the link between the data provided by monitoring technologies on the properties of assets and how the collected data can be analysed and visualised to provide value in decision support. The next step in the report is to use this understanding to develop an appraisal system which could enable technologies in the INFRACOMS technology database to be appraised (scored) in relation to their abilities for data analysis, visualisation, integration and use in decision support.The presented system is referred to as the D3.1 scoring system. It consists of four components covering data visualisation, data analysis, integration within current data architectures and potential for practical decision-making. The present D3.1 report primarily examines the components pertaining to data visualisation and data analysis, while the exploration of the other two components, data architecture and decision support, will be carried out in the D3.2 report. It is proposed that the D3.1 scoring system could be used to appraise the capability of monitoring technologies to support asset management decisions, and would become an integral component of the INFRACOMS Appraisal Toolkit. It will also be used to further filter the current INFRACOMS Technology Database 2.0 technologies as part of the Appraisal Toolkit as INFRACOMS completes the development of the toolkit/database within WP2.
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| 15. |
- da Silva, Edson P., et al.
(författare)
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Combined Optical and Electrical Spectrum Shaping for High-Baud-Rate Nyquist-WDM Transceivers
- 2016
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Ingår i: IEEE Photonics Journal. - : Institute of Electrical and Electronics Engineers (IEEE). - 1943-0655. ; 8:1
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Tidskriftsartikel (refereegranskat)abstract
- We discuss the benefits and limitations of optical time-division multiplexing (OTDM) techniques based on the optical generation of a periodic train of sinc pulses for wavelength-division multiplexing (WDM) transmission at high baud rates. It is shown how the modulated OTDM spectrum bandwidth is related to the optical comb parameters and the pulse shaping of the modulating waveforms in the electrical domain. Such dependence may result in broadening of the modulated spectra, which can degrade the performance of Nyquist-WDM systems due to interchannel crosstalk penalties. However, it is shown and experimentally demonstrated that the same technique of optical pulse train generation can be allied with digital pulse shaping to improve the confinement of the modulated spectrum toward the Nyquist limit independently of the number of OTDM tributaries used. To investigate the benefits of the proposed approach, we demonstrate the first WDM Nyquist-OTDM signal generation based on the periodic train of sinc pulses and electrical spectrum shaping. Straight line transmission of five 112.5-Gbd Nyquist-OTDM dual-polarization quadrature phase-shift keying (QPSK) channels is demonstrated over a dispersion uncompensated link up to 640 km, with full-field coherent detection at the receiver. It is shown that such a design strategy effectively improves the spectral confinement of the modulated OTDM signal, providing a minimum intercarrier crosstalk penalty of 1.5 dB in baud-rate-spaced Nyquist-WDM systems.
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| 16. |
- Fortuin-de Smidt, Melony C., et al.
(författare)
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Effect of exercise training on insulin sensitivity, hyperinsulinemia and ectopic fat in black South African women : a randomized controlled trial
- 2020
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Ingår i: European Journal of Endocrinology. - : Bioscientifica. - 0804-4643 .- 1479-683X. ; 183:1, s. 51-61
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Tidskriftsartikel (refereegranskat)abstract
- Objective: We investigated the effects of a 12-week exercise intervention on insulin sensitivity (SI) and hyperinsulinemia and associated changes in regional and ectopic fat.Research design and methods: Healthy, black South African women with obesity (mean age 23 ± 3.5 years) and of isiXhosa ancestry were randomised into a 12-week aerobic and resistance exercise training group (n = 23) and a no exercise group (control, n = 22). Pre and post-intervention testing included assessment of SI, insulin response to glucose (AIRg), insulin secretion rate (ISR), hepatic insulin extraction (FEL) and disposition index (DI) (AIRg × SI) (frequently sampled i.v. glucose tolerance test); fat mass and regional adiposity (dual-energy X-ray absorptiometry); hepatic, pancreatic and skeletal muscle fat content and abdominal s.c. and visceral adipose tissue volumes (MRI).Results: Exercise training increased VO2peak (mean ± s.d.: 24.9 ± 2.42 to 27.6 ± 3.39 mL/kg/min, P < 0.001), SI (2.0 (1.2–2.8) to 2.2 (1.5–3.7) (mU/l)−1 min−1, P = 0.005) and DI (median (interquartile range): 6.1 (3.6–7.1) to 6.5 (5.6–9.2) × 103 arbitrary units, P = 0.028), and decreased gynoid fat mass (18.5 ± 1.7 to 18.2 ± 1.6%, P < 0.001) and body weight (84.1 ± 8.7 to 83.3 ± .9.7 kg, P = 0.038). None of these changes were observed in the control group, but body weight increased (P = 0.030). AIRg, ISR and FEL, VAT, SAT and ectopic fat were unaltered after exercise training. The increase in SI and DI were not associated with changes in regional or ectopic fat.Conclusion: Exercise training increased SI independent from changes in hyperinsulinemia and ectopic fat, suggesting that ectopic fat might not be a principal determinant of insulin resistance in this cohort.
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| 17. |
- Jia, Shi, et al.
(författare)
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0.4 THz Photonic-Wireless Link with 106 Gbit/s Single Channel Bitrate
- 2018
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Ingår i: Journal of Lightwave Technology. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0733-8724 .- 1558-2213. ; 36:2, s. 610-616
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Tidskriftsartikel (refereegranskat)abstract
- To accommodate the demand of exponentially increased global wireless data traffic, the prospective data rates for wireless communication in the market place will soon reach 100 Gbit/s and beyond. In the lab environment, wireless transmission throughput has been elevated to the level of over 100 Gbit/s attributed to the development of photonic-assisted millimeter wave (MMW) and THz technologies. However, most of recent demonstrations with over 100 Gbit/s data rates are based on spatial or frequency division multiplexing techniques, resulting in increased system's complexity and energy consumption. Here, we experimentally demonstrate a single channel 0.4 THz photonic-wireless link achieving a net data rate of beyond 100 Gbit/s by using a single pair of THz emitter and receiver, without employing any spatial/frequency division multiplexing techniques. The high throughput up to 106 Gbit/s within a single THz channel is enabled by combining spectrally efficient modulation format, ultra-broadband THz transceiver and advanced digital signal processing (DSP) routine. Besides that, our demonstration from system-wide implementation viewpoint also features high transmission stability, and hence shows its great potential to not only decrease the system's complexity, but also meet the requirements of prospective data rates for bandwidth-hungry short-range wireless applications.
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| 18. |
- Kpeglo, D. O., et al.
(författare)
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Radiochemical characterization of produced water from two production offshore oilfields in Ghana
- 2016
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Ingår i: Journal of Environmental Radioactivity. - : Elsevier BV. - 0265-931X. ; 152, s. 35-45
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Tidskriftsartikel (refereegranskat)abstract
- Produced water from two Ghanaian offshore production oilfields has been characterized using alpha spectrometry after radiochemical separation, non-destructive gamma spectrometry and ICP-MS and other complimentary analytical tools. The measured concentrations of main NORM components were in the range of 6.2-22.3 Bq.L-1, 6.4-35.5 Bq.L-1, and 0.7-7.0 Bq.L-4 (f)or Ra-226, Ra-228 and Ra-224 respectively. A good correlation between several physico-chemical parameters and radium isotopes was observed in each production oilfield. The radium concentrations obtained in this study for produced water from the two oilfields of Ghana are of radiological importance and hence there may be the need to put in place measures for future contamination concerns due to their bioavailability in the media and bioaccumulation characteristics. The results will assist in critical decision making for future set up of appropriate national guidelines for the management of NORM waste from the emerging oil and gas industry in Ghana. (C) 2015 Elsevier Ltd. All rights reserved.
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| 19. |
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| 20. |
- Salak, Dragan, et al.
(författare)
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Molecular Outflow in the Reionization-epoch Quasar J2054-0005 Revealed by OH 119 μ m Observations
- 2024
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Ingår i: Astrophysical Journal. - 1538-4357 .- 0004-637X. ; 962:1
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Tidskriftsartikel (refereegranskat)abstract
- Molecular outflows are expected to play a key role in galaxy evolution at high redshift. To study the impact of outflows on star formation at the epoch of reionization, we performed sensitive Atacama Large Millimeter/submillimeter Array observations of OH 119 mu m toward J2054-0005, a luminous quasar at z = 6.04. The OH line is detected and exhibits a P-Cygni profile that can be fitted with a broad blueshifted absorption component, providing unambiguous evidence of an outflow, and an emission component at near-systemic velocity. The mean and terminal outflow velocities are estimated to be v(out )approximate to 670 and 1500 km s(-1), respectively, making the molecular outflow in this quasar one of the fastest at the epoch of reionization. The OH line is marginally spatially resolved for the first time in a quasar at z > 6, revealing that the outflow extends over the central 2 kpc region. The mass outflow rate is comparable to the star formation rate (M-out/SFR similar to 2), indicating rapid (similar to 10(7 )yr) quenching of star formation. The mass outflow rate in a sample of star-forming galaxies and quasars at 4 < z < 6.4 exhibits a positive correlation with the total infrared luminosity, although the scatter is large. Owing to the high outflow velocity, a large fraction (up to similar to 50%) of the outflowing molecular gas may be able to escape from the host galaxy into the intergalactic medium.
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| 21. |
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| 22. |
- Zhang, Fengqiao, et al.
(författare)
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Integration of New and Emerging Technologies into Data Architectures : Deliverable D3.2
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- To appraise the ability to integrate the data provided by a specific technology into an existing data architecture this report commences with the development of an approach to describe the "ideal" data architecture, that can integrate various types of data from new and emerging technologies to facilitate decision making. The data architecture forms a pipeline from raw data creation/delivery to data ingestion, data organization, data analysis and visualisation, until information that is useful for decision making. We then review two existing data architectures as examples in the context of the proposed data architecture pipeline. From the understanding of the two sides – the data properties of technologies and the capabilities of data architectures – we develop an appraisal scoring process to evaluate the ability to integrate the new data into the existing data architecture.To generalize this approach, the report presents a list of questions that can be used by stakeholders to help understand the data architecture used by any NRA (not only limited to the selected examples) when conduct the appraisal. We also develop an appraisal scoring process to evaluate the potential of the technologies to support practical decision making.The outcomes in this report (D3.2) and the previous one (D3.1), complete the INFRACOMS appraisal (scoring) system for the aspects of: data analysis, visualisation, integration into data architecture and potential support for decision making (forming part of the overall appraisal process). An example application of the process is presented for the case of acoustic emission monitoring the wire break in steel cables. In addition, the process has been applied to further technologies in the INFRACOMS database 1.0, and provided in the appendix. It is anticipated that refinement, and further guidance
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| 23. |
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| 24. |
- Zibar, Darko, et al.
(författare)
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Hybrid optical fibre-wireless links at the 75–110 GHz band supporting 100 Gbps transmission capacities
- 2011
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Ingår i: 2011 IEEE International Topical Meeting on Microwave Photonics - Jointly Held with the 2011 Asia-Pacific Microwave Photonics Conference, MWP/APMP 2011. - 9781612847184 ; , s. 445-449
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Konferensbidrag (refereegranskat)abstract
- We present a photonic generation and down-conversion method for realizing a 40Gbps wireless link at the 75-110 GHz band exploiting the recent advances in photonic coherent detection technologies and digital signal processing. Furthermore, we analyze the capacities of hybrid optical fiber-wireless links at the 75-110GHz band, and propose several approaches to overcome the challenges towards 100Gbps wireless capacity.
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