| 1. |
- Apel, Christina, et al.
(författare)
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Safe-and-sustainable-by-design: State of the art approaches and lessons learned from value chain perspectives
- 2024
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Ingår i: Current Opinion in Green and Sustainable Chemistry. - Stockholm : IVL Svenska Miljöinstitutet. - 2452-2236. ; 45, s. 100876-100876
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Tidskriftsartikel (refereegranskat)abstract
- Safe-and-sustainable-by-design (SSbD) is central in the European Chemicals Strategy for Sustainability, yet a common understanding of what SSbD is in concept and in practice isstill needed. A comparison of current SSbD descriptions and approaches was made and lessons learned were derived from value chain discussions (packaging, textile, construction,automotive, energy materials, electronics, and fragrances value chains) to help provide input on how to implement SSbD in practice.Five important building blocks were identified:design, data, risk and sustainability governance, competencies, and social and corporate strategic needs. Other lessons learned include the identification of the biggest safety andsustainability challenges in a lifecycle-thinking approach towards the development of purpose-driven innovations, and connecting trans-disciplinary experts to the innovation process, already from the early phases. A clear understanding of what SSbD is and how to implement the SSbD framework is needed with clear procedures and incentives to support the industrial sector, especially SMEs.
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| 2. |
- Bjerstedt, Sven, et al.
(författare)
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Lessons from jazz improvisation to qualitative inquiry and reflective practice
- 2017
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Ingår i: European Congress of Qualitative Inquiry Proceedings 2017: QUALITY AND REFLEXIVITY IN QUALITATIVE INQUIRY. - 9789067841979 ; , s. 90-94
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In this presentation I will focus on lessons from the arts to qualitative inquiry, especially, what reflection on jazz improvisation may bring to qualitative inquiry. First, I will make the general suggestion that qualitative investigations, seen as reflective practices, have much in common with – and probably much to learn from – jazz improvisational practices. The complex processes of hermeneutic understanding include laying bare the researcher’s pre-understanding as well as, in the interpretation of statements, the dynamics between their holistic coherence and the agent’s intentions. Through interview excerpts, the important phenomenon of breaks in the conversational flow will be shown to have great signficance to qualitative inquiry as a reflective practice, pointing to improvisational practices as relevant providers of solutions to the problematic dynamics of understanding, pre- understanding, self-understanding and misunderstanding. Second, I will discuss a number of ’lessons’ that reflection on jazz improvisation may bring to qualitative research. One lesson concerns the dynamics of different kinds of authenticity. ust as jazz improvisation can be authentic in more than one way, so can research. A second lesson concerns the dynamics of observation and interpretation. Just as jazz improvisation can be viewed both as a response to external impulses and as a manifestation of internal gestures, so can research. A third lesson concerns identity. Just as the notion of changing narrative identity can be seen as key to jazz improvisation, so may an expanded notion of prolonged engagement emerge as highly relevant to qualitative research processes.
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| 3. |
- Nolte, I. M., et al.
(författare)
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Genetic loci associated with heart rate variability and their effects on cardiac disease risk
- 2017
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-wide significant SNPs in eight loci. HRV SNPs tag non-synonymous SNPs (in NDUFA11 and KIAA1755), expression quantitative trait loci (eQTLs) (influencing GNG11, RGS6 and NEO1), or are located in genes preferentially expressed in the sinoatrial node (GNG11, RGS6 and HCN4). Genetic risk scores account for 0.9 to 2.6% of the HRV variance. Significant genetic correlation is found for HRV with heart rate (-0.74 < r(g) < -0.55) and blood pressure (-0.35 < r(g) < -0.20). These findings provide clinically relevant biological insight into heritable variation in vagal heart rhythm regulation, with a key role for genetic variants (GNG11, RGS6) that influence G-protein heterotrimer action in GIRK-channel induced pacemaker membrane hyperpolarization.
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