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- Lauwers, E., et al.
(författare)
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Potential human transmission of amyloid beta pathology: surveillance and risks
- 2020
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Ingår i: Lancet Neurology. - 1474-4422 .- 1474-4465. ; 19:10, s. 872-878
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Tidskriftsartikel (refereegranskat)abstract
- Studies in experimental animals show transmissibility of amyloidogenic proteins associated with prion diseases, Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. Although these data raise potential concerns for public health, convincing evidence for human iatrogenic transmission only exists for prions and amyloid beta after systemic injections of contaminated growth hormone extracts or dura mater grafts derived from cadavers. Even though these procedures are now obsolete, some reports raise the possibility of iatrogenic transmission of amyloid beta through putatively contaminated neurosurgical equipment. Iatrogenic transmission of amyloid beta might lead to amyloid deposition in the brain parenchyma and blood vessel walls, potentially resulting in cerebral amyloid angiopathy after several decades. Cerebral amyloid angiopathy can cause life-threatening brain haemorrhages; yet, there is no proof that the transmission of amyloid can also lead to Alzheimer's dementia. Large, long-term epidemiological studies and sensitive, cost-efficient tools to detect amyloid are needed to better understand any potential routes of amyloid beta transmission and to clarify whether other similar proteopathic seeds, such as tau or alpha-synuclein, can also be transferred iatrogenically.
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- Hjalgrim, H, et al.
(författare)
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Cancer incidence in blood transfusion recipients
- 2007
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Ingår i: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 1460-2105 .- 0027-8874. ; 99:24, s. 1864-1874
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Tidskriftsartikel (refereegranskat)
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- Agren, A, et al.
(författare)
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In response
- 2014
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Ingår i: Anesthesia and analgesia. - 1526-7598. ; 119:6, s. 1453-1453
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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- Edgren, Aina, 1995, et al.
(författare)
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Alloying of C40-structured Mo(Si,Al) 2 with Nb, Ta and V
- 2023
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Ingår i: Materials Letters. - 1873-4979 .- 0167-577X. ; 353
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Tidskriftsartikel (refereegranskat)abstract
- Alloying of Mo(Si,Al)2, prepared by sintering, with Nb, Ta or V has been studied. All alloyed materials retained the C40-structured matrix phase of the un-alloyed reference material. The concentration of alloying elements in the C40 phase reached 0.4–1.6 at.% (approximately 20–50 % of the intended levels), and the remaining alloying content was dissolved in the minority D8m- and D88-structured (Mo,X)5(Si,Al)3 phases. V-alloying also promoted the formation of C54-structured (Mo,V)(Si,Al)2.
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38. |
- Edgren, Aina, 1995, et al.
(författare)
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Competing High-Temperature Deformation Mechanisms in Mo(Si,Al) 2 –Al 2 O 3 Composites
- 2024
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Ingår i: Metallurgical and Materials Transactions A: Physical Metallurgy and Materials Science. - 1073-5623. ; 55:9, s. 3220-3225
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Tidskriftsartikel (refereegranskat)abstract
- Mo(Si,Al)2–Al2O3 composites were tested in four-point bending at 1300 °C. The addition of Al2O3 led to a decrease in grain size, and a subsequent decrease in strength for materials containing up to 15 wt pct Al2O3. At higher Al2O3 fractions, the decrease in grain size saturates and the strength is recovered as the Al2O3 particles prevent grain boundary sliding.
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- Edgren, G, et al.
(författare)
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Enigmatic sex disparities in cancer incidence
- 2012
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Ingår i: European journal of epidemiology. - : Springer Science and Business Media LLC. - 1573-7284 .- 0393-2990. ; 27:3, s. 187-196
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Tidskriftsartikel (refereegranskat)
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