| 1. |
- Hansson, Linnea J., et al.
(författare)
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Autoplant—Autonomous Site Preparation and Tree Planting for a Sustainable Bioeconomy
- 2024
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Ingår i: Forests. - : MDPI. - 1999-4907. ; 15:2
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Tidskriftsartikel (refereegranskat)abstract
- Sustainable forestry requires efficient regeneration methods to ensure that new forests are established quickly. In Sweden, 99% of the planting is manual, but finding labor for this arduous work is difficult. An autonomous scarifying and planting machine with high precision, low environmental impact, and a good work environment would meet the needs of the forest industry. For two years, a collaborative group of researchers, manufacturers, and users (forest companies) has worked together on developing and testing a new concept for autonomous forest regeneration (Autoplant). The concept comprises several subsystems, i.e., regeneration and route planning, autonomous driving (path planning), new technology for forest regeneration with minimal environmental impact, automatic plant management, crane motion planning, detection of planting spots, and follow-up. The subsystems were tested separately and integrated together during a field test at a clearcut. The concept shows great potential, especially from an environmental perspective, with significantly reduced soil disturbances, from approximately 50% (the area proportion of the area disturbed by disc trenching) to less than 3%. The Autoplant project highlights the challenges and opportunities related to future development, e.g., the relation between machine cost and operating speed, sensor robustness in response to vibrations and weather, and precision in detecting the size and type of obstacles during autonomous driving and planting.
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| 2. |
- Steneberg, Pär, et al.
(författare)
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PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes patients
- 2018
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Ingår i: JCI INSIGHT. - : American Society for Clinical Investigation. - 2379-3708. ; 3:12
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Tidskriftsartikel (refereegranskat)abstract
- AMPK activated protein kinase (AMPK), a master regulator of energy homeostasis, is activated in response to an energy shortage imposed by physical activity and caloric restriction. We here report on the identification of PAN-AMPK activator O304, which - in diet-induced obese mice - increased glucose uptake in skeletal muscle, reduced beta cell stress, and promoted beta cell rest. Accordingly, O304 reduced fasting plasma glucose levels and homeostasis model assessment of insulin resistance (HOMA-IR) in a proof-of-concept phase IIa clinical trial in type 2 diabetes (T2D) patients on Metformin. T2D is associated with devastating micro-and macrovascular complications, and O304 improved peripheral microvascular perfusion and reduced blood pressure both in animals and T2D patients. Moreover, like exercise, O304 activated AMPK in the heart, increased cardiac glucose uptake, reduced cardiac glycogen levels, and improved left ventricular stroke volume in mice, but it did not increase heart weight in mice or rats. Thus, O304 exhibits a great potential as a novel drug to treat T2D and associated cardiovascular complications.
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| 3. |
- Al Moubayed, Samer, et al.
(författare)
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Animated Faces for Robotic Heads : Gaze and Beyond
- 2011
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Ingår i: Analysis of Verbal and Nonverbal Communication and Enactment. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642257742 ; , s. 19-35
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Konferensbidrag (refereegranskat)abstract
- We introduce an approach to using animated faces for robotics where a static physical object is used as a projection surface for an animation. The talking head is projected onto a 3D physical head model. In this chapter we discuss the different benefits this approach adds over mechanical heads. After that, we investigate a phenomenon commonly referred to as the Mona Lisa gaze effect. This effect results from the use of 2D surfaces to display 3D images and causes the gaze of a portrait to seemingly follow the observer no matter where it is viewed from. The experiment investigates the perception of gaze direction by observers. The analysis shows that the 3D model eliminates the effect, and provides an accurate perception of gaze direction. We discuss at the end the different requirements of gaze in interactive systems, and explore the different settings these findings give access to.
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| 4. |
- Albertsson, Ann-Christine, 1945-, et al.
(författare)
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Increased biocompatibility by surface modification
- 2004
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Ingår i: Abstracts of Papers of the American Chemical Society. - : American Chemical Society (ACS). - 0065-7727. ; 228, s. U508-U508
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 5. |
- Andersson, Sandra, et al.
(författare)
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The Transcriptomic and Proteomic Landscapes of Bone Marrow and Secondary Lymphoid Tissues
- 2014
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:12, s. e115911-
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Tidskriftsartikel (refereegranskat)abstract
- Background: The sequencing of the human genome has opened doors for global gene expression profiling, and the immense amount of data will lay an important ground for future studies of normal and diseased tissues. The Human Protein Atlas project aims to systematically map the human gene and protein expression landscape in a multitude of normal healthy tissues as well as cancers, enabling the characterization of both housekeeping genes and genes that display a tissue-specific expression pattern. This article focuses on identifying and describing genes with an elevated expression in four lymphohematopoietic tissue types (bone marrow, lymph node, spleen and appendix), based on the Human Protein Atlas-strategy that combines high throughput transcriptomics with affinity-based proteomics. Results: An enriched or enhanced expression in one or more of the lymphohematopoietic tissues, compared to other tissue-types, was seen for 693 out of 20,050 genes, and the highest levels of expression were found in bone marrow for neutrophilic and erythrocytic genes. A majority of these genes were found to constitute well-characterized genes with known functions in lymphatic or hematopoietic cells, while others are not previously studied, as exemplified by C19ORF59. Conclusions: In this paper we present a strategy of combining next generation RNA-sequencing with in situ affinity-based proteomics in order to identify and describe new gene targets for further research on lymphatic or hematopoietic cells and tissues. The results constitute lists of genes with enriched or enhanced expression in the four lymphohematopoietic tissues, exemplified also on protein level with immunohistochemical images.
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| 6. |
- Artman, Henrik, 1968-, et al.
(författare)
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Effektiv miljötillsyn : slutrapport
- 2013
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Målsättningen har varit att ta fram ny kunskap inom miljötillsynen och därigenom uppnå en effektivare miljötillsyn samt att få in nya vetenskapliga perspektiv på miljötillsyn.I rapporten studeras metoder för inspektioner och det kommunikativa samspelet mellan inspektören och företrädare för den verksamhet som inspekteras, hur den institutionella ramen för inspektionsprocessen fungerar samt visar på möjligheter att mäta effekterna av inspektioner och tillsyn.Naturvårdsverket kommer att ha resultatet som ett kunskapsunderlag i fortsatt arbete med tillsynsvägledning och utveckling av hur tillsyn och tillsynsvägledning kan följas upp och utvärderas.
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| 7. |
- Beskow, Jonas, et al.
(författare)
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Face-to-Face Interaction and the KTH Cooking Show
- 2010
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Ingår i: Development of multimodal interfaces. - Berlin, Heidelberg : Springer Berlin Heidelberg. - 9783642123962 ; , s. 157-168
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Konferensbidrag (refereegranskat)abstract
- We share our experiences with integrating motion capture recordings in speech and dialogue research by describing (1) Spontal, a large project collecting 60 hours of video, audio and motion capture spontaneous dialogues, is described with special attention to motion capture and its pitfalls; (2) a tutorial where we use motion capture, speech synthesis and an animated talking head to allow students to create an active listener; and (3) brief preliminary results in the form of visualizations of motion capture data over time in a Spontal dialogue. We hope that given the lack of writings on the use of motion capture for speech research, these accounts will prove inspirational and informative.
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| 8. |
- Beskow, Jonas, et al.
(författare)
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Innovative interfaces in MonAMI : The Reminder
- 2008
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Ingår i: Perception In Multimodal Dialogue Systems, Proceedings. - Berlin, Heidelberg : Springer Berlin Heidelberg. - 9783540693680 ; , s. 272-275
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Konferensbidrag (refereegranskat)abstract
- This demo paper presents the first version of the Reminder, a prototype ECA developed in the European project MonAMI, which aims at "main-streaming accessibility in consumer goods and services, using advanced technologies to ensure equal access, independent living and participation for all". The Reminder helps users to plan activities and to remember what to do. The prototype merges ECA technology with other, existing technologies: Google Calendar and a digital pen and paper. This innovative combination of modalities allows users to continue using a paper calendar in the manner they are used to, whilst the ECA provides verbal notifications on what has been written in the calendar. Users may also ask questions such as "When was I supposed to meet Sara?" or "What's on my schedule today?"
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| 9. |
- Beskow, Jonas, et al.
(författare)
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Multimodal Interaction Control
- 2009
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Ingår i: Computers in the Human Interaction Loop. - Berlin/Heidelberg : Springer Berlin/Heidelberg. - 9781848820531 - 9781848820548 ; , s. 143-158
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Bokkapitel (refereegranskat)
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| 10. |
- Beskow, Jonas, et al.
(författare)
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Speech technology in the European project MonAMI
- 2008
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Ingår i: Proceedings of FONETIK 2008. - Gothenburg, Sweden : University of Gothenburg. - 9789197719605 ; , s. 33-36
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- This paper describes the role of speech and speech technology in the European project MonAMI, which aims at “mainstreaming ac-cessibility in consumer goods and services, us-ing advanced technologies to ensure equal ac-cess, independent living and participation for all”. It presents the Reminder, a prototype em-bodied conversational agent (ECA) which helps users to plan activities and to remember what to do. The prototype merges speech technology with other, existing technologies: Google Cal-endar and a digital pen and paper. The solution allows users to continue using a paper calendar in the manner they are used to, whilst the ECA provides notifications on what has been written in the calendar. Users may also ask questions such as “When was I supposed to meet Sara?” or “What’s on my schedule today?”
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| 11. |
- Beskow, Jonas, et al.
(författare)
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The MonAMI Reminder : a spoken dialogue system for face-to-face interaction
- 2009
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Ingår i: Proceedings of the 10th Annual Conference of the International Speech Communication Association, INTERSPEECH 2009. - Brighton, U.K. ; , s. 300-303
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Konferensbidrag (refereegranskat)abstract
- We describe the MonAMI Reminder, a multimodal spoken dialogue system which can assist elderly and disabled people in organising and initiating their daily activities. Based on deep interviews with potential users, we have designed a calendar and reminder application which uses an innovative mix of an embodied conversational agent, digital pen and paper, and the web to meet the needs of those users as well as the current constraints of speech technology. We also explore the use of head pose tracking for interaction and attention control in human-computer face-to-face interaction.
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| 12. |
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| 13. |
- Costa, Carolina, et al.
(författare)
-
Emulsion Formation and Stabilization by Biomolecules : The Leading Role of Cellulose.
- 2019
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Ingår i: Polymers. - : MDPI AG. - 2073-4360. ; 11:10
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Tidskriftsartikel (refereegranskat)abstract
- Emulsion stabilization by native cellulose has been mainly hampered because of its insolubility in water. Chemical modification is normally needed to obtain water-soluble cellulose derivatives. These modified celluloses have been widely used for a range of applications by the food, cosmetic, pharmaceutic, paint and construction industries. In most cases, the modified celluloses are used as rheology modifiers (thickeners) or as emulsifying agents. In the last decade, the structural features of cellulose have been revisited, with particular focus on its structural anisotropy (amphiphilicity) and the molecular interactions leading to its resistance to dissolution. The amphiphilic behavior of native cellulose is evidenced by its capacity to adsorb at the interface between oil and aqueous solvent solutions, thus being capable of stabilizing emulsions. In this overview, the fundamentals of emulsion formation and stabilization by biomolecules are briefly revisited before different aspects around the emerging role of cellulose as emulsion stabilizer are addressed in detail. Particular focus is given to systems stabilized by native cellulose, either molecularly-dissolved or not (Pickering-like effect).
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| 14. |
- Costa, Carolina, et al.
(författare)
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Interfacial activity and emulsion stabilization of dissolved cellulose
- 2019
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Ingår i: Journal of Molecular Liquids. - : Elsevier B.V.. - 0167-7322 .- 1873-3166. ; 292
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Tidskriftsartikel (refereegranskat)abstract
- Some aspects of the interfacial behavior of cellulose dissolved in an aqueous solvent were investigated. Cellulose was found to significantly decrease the interfacial tension (IFT) between paraffin oil and 85 wt% phosphoric acid aqueous solutions. This decrease was similar in magnitude to that displayed by non-ionic cellulose derivatives. Cellulose's interfacial activity indicated a significant amphiphilic character and that the interfacial activity of cellulose derivatives is not only related to the derivatization but inherent in the cellulose backbone. This finding suggests that cellulose would have the ability of stabilizing dispersions, like oil-in-water emulsions in a similar way as a large number of cellulose derivatives. In its molecularly dissolved state, cellulose proved to be able to stabilize emulsions of paraffin in the polar solvent on a short-term. However, long-term stability against drop-coalescence was possible to achieve by a slight change in the amphiphilicity of cellulose, effected by a slight increase in pH. These emulsions exhibited excellent stability against coalescence/oiling-off over a period of one year. Ageing of the cellulose solution before emulsification (resulting in molecular weight reduction) was found to favour the creation of smaller droplets.
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| 15. |
- Costa, Carolina, et al.
(författare)
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Lignin enhances cellulose dissolution in cold alkali
- 2021
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Ingår i: Carbohydrate Polymers. - : Elsevier BV. - 0144-8617 .- 1879-1344. ; 274
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Tidskriftsartikel (refereegranskat)abstract
- Aqueous sodium hydroxide solutions are extensively used as solvents for lignin in kraft pulping. These are also appealing systems for cellulose dissolution due to their inexpensiveness, ease to recycle and low toxicity. Cellulose dissolution occurs in a narrow concentration region and at low temperatures. Dissolution is often incomplete but additives, such as zinc oxide or urea, have been found to significantly improve cellulose dissolution. In this work, lignin was explored as a possible beneficial additive for cellulose dissolution. Lignin was found to improve cellulose dissolution in cold alkali, extending the NaOH concentration range to lower values. The regenerated cellulose material from the NaOH-lignin solvents was found to have a lower crystallinity and crystallite size than the samples prepared in the neat NaOH and NaOH-urea solvents. Beneficial lignin-cellulose interactions in solution state appear to be preserved under coagulation and regeneration, reducing the tendency of crystallization of cellulose.
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| 16. |
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| 17. |
- Costa, Carolina, et al.
(författare)
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On the formation and stability of cellulose-based emulsions in alkaline systems : Effect of the solvent quality
- 2022
-
Ingår i: Carbohydrate Polymers. - : Elsevier BV. - 0144-8617 .- 1879-1344. ; 286
-
Tidskriftsartikel (refereegranskat)abstract
- With amphiphilic properties, cellulose molecules are expected to adsorb at the O/W interface and be capable of stabilizing emulsions. The effect of solvent quality on the formation and stability of cellulose-based O/W emulsions was evaluated in different alkaline systems: NaOH, NaOH-urea and tetrabutylammonium hydroxide (TBAH). The optimal solvency conditions for cellulose adsorption at the O/W interface were found for the alkaline solvent with an intermediate polarity (NaOH-urea), which is in line with the favorable conditions for adsorption of an amphiphilic polymer. A very good solvency (in TBAH) and the interfacial activity of the cation lead to lack of stability because of low cellulose adsorption. However, to achieve long-term stability and prevent oil separation in NaOH-urea systems, further reduction in cellulose's solvency was needed, which was achieved by a change in the pH of the emulsions, inducing the regeneration of cellulose at the surface of the oil droplets (in-situ regeneration).
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| 18. |
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| 19. |
- Djureinovic, Dijana, et al.
(författare)
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Profiling cancer testis antigens in non-small-cell lung cancer
- 2016
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Ingår i: JCI INSIGHT. - : American Society for Clinical Investigation. - 2379-3708. ; 1:10
-
Tidskriftsartikel (refereegranskat)abstract
- Cancer testis antigens (CTAs) are of clinical interest as biomarkers and present valuable targets for immunotherapy. To comprehensively characterize the CTA landscape of non-small-cell lung cancer (NSCLC), we compared RNAseq data from 199 NSCLC tissues to the normal transcriptome of 142 samples from 32 different normal organs. Of 232 CTAs currently annotated in the Caner Testis Database (CTdatabase), 96 were confirmed in NSCLC. To obtain an unbiased CTA profile of NSCLC, we applied stringent criteria on our RNAseq data set and defined 90 genes as CTAs, of which 55 genes were not annotated in the CTdatabase, thus representing potential new CTAs. Cluster analysis revealed that CTA expression is histology dependent and concurrent expression is common. IHC confirmed tissue-specific protein expression of selected new CTAs (TKTL1, TGIF2LX, VCX, and CXORF67). Furthermore, methylation was identified as a regulatory mechanism of CTA expression based on independent data from The Cancer Genome Atlas. The proposed prognostic impact of CTAs in lung cancer was not confirmed, neither in our RNAseq cohort nor in an independent meta-analysis of 1,117 NSCLC cases. In summary, we defined a set of 90 reliable CTAs, including information on protein expression, methylation, and survival association. The detailed RNAseq catalog can guide biomarker studies and efforts to identify targets for immunotherapeutic strategies.
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| 20. |
- Edlund, Ann-Catrine, 1959-, et al.
(författare)
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Sealing
- 2016
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Ingår i: Encyclopedia of the Barents Region. - Oslo : Pax Forlag. - 9788253038599 ; , s. 312-313
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Bokkapitel (refereegranskat)
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| 21. |
- Edlund, Ann-Catrine, 1959-, et al.
(författare)
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Sealing
- 2016
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Ingår i: Encyclopedia of the Barents Region. - Oslo : Pax Forlag. - 9788253038599 ; , s. 312-313
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Bokkapitel (refereegranskat)
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| 22. |
- Edlund, Björn, et al.
(författare)
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A Method of Finding HCT Roundwood Corridors for Reduction of GHG Emissions and Fuel Costs in Sweden
- 2020
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Ingår i: Forests. - : MDPI AG. - 1999-4907. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Background and Objectives: in Sweden during 2016, 71.6 million metric tonnes (t) of forest biomass (roundwood and forest fuels) were transported by truck, corresponding to approximately 15% of all national goods truck transport. To reduce the environmental impact of forest product transports and meet Swedish climate goals, the use of 90 t high-capacity transport (HCT) trucks on well-chosen routes has been identified as one potential measure. The objective was, therefore, to develop a method of finding the geographical occurrence of potential roundwood HCT corridors for 90 t trucks, as well as estimating their environmental and economic potential in comparison to the conventional 74 t-truck transport system for Swedish conditions. Materials and Methods: the study used data from actual roundwood transports during 2016 along with a digitalization of the Swedish road network (National Road Database, SNVDB) for corridor identification. In four steps we: 1) identified supportive networks, 2) identified flow supporting corridors on the technically supportive networks, 3) applied a calibrated route finder (CRF) to route relevant transports both directly from the landing to the receiver and via the corridor, gathering drive distance information and, for example, 4) analyzed transports fuel consumption and potential CO2 savings. Results: Results showed there was annual potential for 25 HCT corridors throughout Sweden to employ 20 90 t trucks to transport 2.5 Mt of roundwood, reducing up to 5500 t of CO2 and euro3.1 M in fuel costs. Conclusions: the study reinforces previous studies' findings concerning economic and environmental potential using HCT vehicles and identifies terminal establishment and management costs as a bottleneck in successful large-scale implementation of HCT corridors.
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| 23. |
- Edlund, Björn, et al.
(författare)
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Quad Bike Riders’ Attitudes toward and Use of Safety Technologies
- 2019
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Ingår i: Journal of Agricultural Safety and Health. - : American Society of Agricultural and Biological Engineers (ASABE). - 1074-7583 .- 1943-7846. ; 25, s. 169-187
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Tidskriftsartikel (refereegranskat)abstract
- Worldwide, the number of quad bike-related injuries and fatalities has increased over the last 30 years and, although quad bike safety has become increasingly important over the last decade, greater understanding of the risks associated with these vehicles is required. This study aimed to improve understanding of the interrelationships between risk perception, risk management, and the use of safety technologies in quad bike operation. A total of 70 quad bike riders were interviewed in two sets of interviews: one targeting riders visiting two forestry fairs, and the other targeting riders with quad bikes equipped with ROPS. The interviews showed that the quad bike riders had a tendency for externalization of risk. This result possibly derives from the articulation and allocation of blame; the majority of respondents saw the problem of quad bike safety as a result of faulty rider behavior, thus shifting focus away from the technology as well as from themselves. This also applies to many of the interviewed ROPS owners, as one of their prime motivators in acquiring ROPS was to improve the safety of others rather than their own safety.
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| 24. |
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| 25. |
- Edlund, Björn
(författare)
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Safety interventions in Swedish small-scale forestry
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In private non-industrial forestry, self-employed work has long been associated with high risks for injuries. This thesis is based on four studies that focused on two of the major high-risk activities in this sector in Sweden: two on felling, de-limbing and bucking trees with a chainsaw; and two on off-road use of quad bikes.The main intervention targeting the risk of chainsaw injuries is promotion of safe work practice, thus chainsaw training is seen an important tool. However, the provided training must effectively transfer knowledge and skill to the trainees, and more knowledge of the effectiveness of this transfer is required.Thus, half of this thesis is devoted to the Swedish chainsaw license and training. The results show that chainsaw training increases relevant knowledge and skill, and seems to result in changes in chainsaw users’ behaviour. Although knowledge retention was found to be relatively poor just a year after obtaining a licence (which generally involves training as a theoretical and practical examinations must be passed), no clear further effect of time in the period between one and nine years after receiving one was detected. The results also revealed no clear effect of time on skill retention.The use of quad bikes is associated with high risks for rollover injuries. A suggested intervention targeting this risk is to use an operator protective device (OPD) intended to create a safe space for the operator during a rollover incident, thus preventing the quad bike from crushing the operator. Although such devices have been available for a long time, none have been widely accepted, and many questions regarding optimal kinds of OPDs, their effects and implementation have not been adequately addressed. The other half of this thesis is thus devoted to the development and implementation of quad bike OPDs. The results showed, inter alia, that many quad bike users' understanding of quad bike safety is characterized by a belief that not all users are at risk and that risks are not equally distributed. Thus, several participating users decided to acquire an OPD not necessarily to increase their own safety but rather to increase the safety of others.
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| 26. |
- Edlund, Björn, et al.
(författare)
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The effect of rollover protection systems and trailers on quad bike stability
- 2020
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Ingår i: International Journal of Forest Engineering. - : Informa UK Limited. - 1494-2119 .- 1913-2220. ; 31, s. 95-105
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Tidskriftsartikel (refereegranskat)abstract
- Quad bikes are light-weight vehicles which are used for transportation of personnel, equipment, and material in forestry operations such as planning, logging, planting, and fire-fighting. With increased quad bike usage, serious injuries have become an increasing concern. The most common forms of severe incidents occur when a quad bike loses stability, causing injuries as it rolls over the rider trapped beneath. The risk of injuries during a rollover incident can be decreased by equipping the vehicle with rollover protection systems (ROPS), but since ROPS tend to decrease the stability of quad bikes, their use can be a trade-off between the risk of overturning and the outcome of any such incident. In this study, we examine the effects of approach angle, trailer load, ROPS and different hardware configurations on a quad bike’s static stability. We found that approach angle and trailer configurations influenced the vehicle’s stability, although the effect was difficult to quantify in a static environment. Furthermore, the quad bike’s stability was negatively influenced by equipping it with a heavy (44 kg) ROPS. It reduced the static stability by an average of 5.1°, while a light (14.7 kg) prototype ROPS only reduced the vehicle’s static stability by an average of 1.0°. The negative impact a ROPS has on a quad bike’s lateral stability could be effectively counteracted by increasing the quad bike’s track width. Increasing track width by less than 2% (20 mm) compensated for any negative impact that the light prototype ROPS had on the quad bike’s lateral stability.
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| 27. |
- Edlund, Jonathan, et al.
(författare)
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Validation and quantification of left ventricular function during exercise and free breathing from real-time cardiac magnetic resonance images
- 2022
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- Exercise cardiovascular magnetic resonance (CMR) can unmask cardiac pathology not evident at rest. Real-time CMR in free breathing can be used, but respiratory motion may compromise quantification of left ventricular (LV) function. We aimed to develop and validate a post-processing algorithm that semi-automatically sorts real-time CMR images according to breathing to facilitate quantification of LV function in free breathing exercise. A semi-automatic algorithm utilizing manifold learning (Laplacian Eigenmaps) was developed for respiratory sorting. Feasibility was tested in eight healthy volunteers and eight patients who underwent ECG-gated and real-time CMR at rest. Additionally, volunteers performed exercise CMR at 60% of maximum heart rate. The algorithm was validated for exercise by comparing LV mass during exercise to rest. Respiratory sorting to end expiration and end inspiration (processing time 20 to 40 min) succeeded in all research participants. Bias ± SD for LV mass was 0 ± 5 g when comparing real-time CMR at rest, and 0 ± 7 g when comparing real-time CMR during exercise to ECG-gated at rest. This study presents a semi-automatic algorithm to retrospectively perform respiratory sorting in free breathing real-time CMR. This can facilitate implementation of exercise CMR with non-ECG-gated free breathing real-time imaging, without any additional physiological input.
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| 28. |
- Edlund, Klara, et al.
(författare)
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Introduktion
- 2009. - 1
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Ingår i: Fetma - del 1. - Lund : Studentlitteratur. - 9789144018928 ; , s. 27-31
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 29. |
- Edlund, Sara, 1983-, et al.
(författare)
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Facing negative emotions : Evaluation of a brief training in validating communication for contact nurses in cancer care
- 2023
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Ingår i: European Journal of Oncology Nursing. - : Elsevier. - 1462-3889 .- 1532-2122. ; 66
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Tidskriftsartikel (refereegranskat)abstract
- Background: Contact nurses in cancer care (CNCC) often face challenges when communicating with patients and their families. The overall aim was to evaluate a brief digital validation training for CNCC, to test whether it was associated with increased validation and decreased invalidation. Associations between communication skills in validation and markers of work-related stress were also investigated. Methods: This intervention study investigated associations between the training and validation skills using a within-group design with repeated measures (at pre, post, and eight-week follow-up). Additionally, associations between the training and occupational self-efficacy, self-validation, and exhaustion symptoms were explored. Results: Seventeen CNCCs (all female with relatively long work experience) completed a five-week digital training program. Results indicated a statistically significant increase in validation and a statistically significant decrease in invalidation, showing that the nurses improved their communication skills following the training. No changes were found in markers of work-related stress. Conclusion: The results indicate that digital validation training for CNCCs is potentially beneficial by means of improving communication skills. This study further demonstrates that a brief digital training in validating communication to CNCC is associated with improved person-centered communication regarding strong negative emotions.
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| 30. |
- Eivazihollagh, Alireza, et al.
(författare)
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One-pot synthesis of cellulose-templated copper nanoparticles with antibacterial properties
- 2017
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Ingår i: Materials letters (General ed.). - : Elsevier BV. - 0167-577X .- 1873-4979. ; 187, s. 170-172
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Tidskriftsartikel (refereegranskat)abstract
- We report a facile in situ synthesis of spherical copper nanoparticles (NPs) templated by a gelled cellulose II matrix under alkaline aqueous reaction conditions. In under 20 min, the hybrid material could be obtained in a one-pot reaction. Field-emission scanning electron microscopy (FE-SEM) revealed that the polycrystalline NPs of 200–500 nm were well distributed in the regenerated cellulose matrix. The average Cu crystallite size was of the order of 20 nm, as estimated from both X-ray diffraction (XRD) and FE-SEM. XRD data also indicated that the composite contained up to approximately 20% Cu2O. In suspensions containing the hybrid material, growth of Escerichia coli and Staphylococcus aureus strains was inhibited by 80% and 95%, respectively, after 72 h. The synthesis procedure offers a general approach to designing various low-cost hybrid materials of almost any shape, and the concept could be extended to utilization areas such as catalysis, functional textiles, and food packaging as well as to electronic applications.
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| 31. |
- Eivazihollagh, Alireza, et al.
(författare)
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Vesicle-templated all-cellulose nanocapsules
- 2019
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Konferensbidrag (refereegranskat)abstract
- Polymeric multilayers capsules constructed using the layer-by-layer (LbL) technique are interesting candidates for the purposes of storage, encapsulation and release in a wide range of biomedical applications. In the current study, cellulose-based nanocapsules were produced via the LbL technique. In this procedure, alternating deposition of the two biocompatible polymers anionic cellulose, carboxymethylcellulose (CMC), and cationic cellulose, quaternized hydroxyethylcellulose ethoxylate (QHECE), on a cationic vesicular template made of didodecyldimethylammonium bromide (DDAB), was performed. The obtained nanocapsules, were characterized by dynamic light scattering (DLS), ⇣ potential measurements, and field-emission scanning electron microscopy (FE-SEM). DLS measurements revealed that the size of the spheres is about hundreds of nanometer with polydispersity index (PDI) values between 0.2 and 0.3, indicating a relatively homogeneous size distribution. In addition, FESEM characterization also indicated the shape and size of obtained material. The surface charge analysis of the nanocapsules by ⇣ potential measurements indicated the presence of electrostatically stabilized nanoparticles. The values of diameter, PDI and surface charge for cationic vesicles coated by CMC were 204 nm, 0.26 and –38 mV, respectively. After deposition of QHECE, the diameter, PDI, and surface charge were about 265 nm, 0.36 and +32.5 mV, respectively. Figure 1 shows FE-SEM images of cellulose nanoparticles fabricated via LbL deposition of polyelectrolyte layers. As seen in the microscopy images, the shape of the core-shell particles are not fully spherical which could be due to drying e↵ects of the sample before FE-SEM characterization. The construction of cellulose nanocontainers by using an alternating deposition of oppositely charged biobased polyelectrolytes on vesicles o↵ers several advantages such as simplicity, reproducibility, biocompatibility, low-cost, mild reaction conditions, and high controllability over the thickness and composition of the shell.
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| 32. |
- Fagerberg, Linn, et al.
(författare)
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Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
- 2014
-
Ingår i: Molecular & Cellular Proteomics. - 1535-9476 .- 1535-9484. ; 13:2, s. 397-406
-
Tidskriftsartikel (refereegranskat)abstract
- Global classification of the human proteins with regards to spatial expression patterns across organs and tissues is important for studies of human biology and disease. Here, we used a quantitative transcriptomics analysis (RNA-Seq) to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody- based profiling of the same tissues. To present the data, we launch a new version of the Human Protein Atlas that integrates RNA and protein expression data corresponding to 80% of the human protein-coding genes with access to the primary data for both the RNA and the protein analysis on an individual gene level. We present a classification of all human protein-coding genes with regards to tissue-specificity and spatial expression pattern. The integrative human expression map can be used as a starting point to explore the molecular constituents of the human body.
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| 33. |
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| 34. |
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| 35. |
- Fjeld, Dag, et al.
(författare)
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Accelerated learning for wood supply managers - the next generation of on-line training tools
- 2024
-
Ingår i: International Journal of Forest Engineering. - 1494-2119 .- 1913-2220. ; 35, s. 3-10
-
Tidskriftsartikel (refereegranskat)abstract
- The Virtual Wood Supply Arena is an on-line training environment for managing roundwood purchase, production and transport in cut-to-length supply systems. The purpose of its development was accelerated training for coordination of these functions under realistic operating conditions. It offers 8- and 12-week scenarios for supplying five mills. Weekly planning is done for 10 harvesting teams and 10 trucks in a Swedish case geography while tracking mill delivery fulfillment under weekly trafficability restrictions. The purpose of this paper is to introduce the training environment and report the progression of student performance after 2 years of use in university-level training. Student teams reached full delivery fulfillment within three training runs. After familiarization during an introductory run, a complete 12-week scenario took four effective hours to complete. Delivery fulfillment increased from 82 to 95 and 100% between the first, second and third training runs. The progression of team performance included a 36% reduction of relocation distances for harvesting teams and 11% reduction of transport distances for hauling from forest to mill. By the third training run these performance levels were attained with less than 2 weeks of inventory for both the purchase bank and roadside stocks.
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| 36. |
- Gremel, Gabriela, et al.
(författare)
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The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling
- 2015
-
Ingår i: Journal of gastroenterology. - : Springer. - 0944-1174 .- 1435-5922. ; 50:1, s. 46-57
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The gastrointestinal tract (GIT) is subdivided into different anatomical organs with many shared functions and characteristics, but also distinct differences. We have combined a genome-wide transcriptomics analysis with immunohistochemistry-based protein profiling to describe the gene and protein expression patterns that define the human GIT. METHODS: RNA sequencing data derived from stomach, duodenum, jejunum/ileum and colon specimens were compared to gene expression levels in 23 other normal human tissues analysed with the same method. Protein profiling based on immunohistochemistry and tissue microarrays was used to sub-localize the corresponding proteins with GIT-specific expression into sub-cellular compartments and cell types. RESULTS: Approximately 75% of all human protein-coding genes were expressed in at least one of the GIT tissues. Only 51 genes showed enriched expression in either one of the GIT tissues and an additional 83 genes were enriched in two or more GIT tissues. The list of GIT-enriched genes with validated protein expression patterns included various well-known but also previously uncharacterised or poorly studied genes. For instance, the colon-enriched expression of NXPE family member 1 (NXPE1) was established, while NLR family, pyrin domain-containing 6 (NLRP6) expression was primarily found in the human small intestine. CONCLUSIONS: We have applied a genome-wide analysis based on transcriptomics and antibody-based protein profiling to identify genes that are expressed in a specific manner within the human GIT. These genes and proteins constitute important starting points for an improved understanding of the normal function and the different states of disease associated with the GIT.
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| 37. |
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| 38. |
- Habuka, Masato, et al.
(författare)
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The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
- 2014
-
Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:12, s. e116125-
-
Tidskriftsartikel (refereegranskat)abstract
- To understand renal functions and disease, it is important to define the molecular constituents of the various compartments of the kidney. Here, we used comparative transcriptomic analysis of all major organs and tissues in the human body, in combination with kidney tissue micro array based immunohistochemistry, to generate a comprehensive description of the kidney-specific transcriptome and proteome. A special emphasis was placed on the identification of genes and proteins that were elevated in specific kidney subcompartments. Our analysis identified close to 400 genes that had elevated expression in the kidney, as compared to the other analysed tissues, and these were further subdivided, depending on expression levels, into tissue enriched, group enriched or tissue enhanced. Immunohistochemistry allowed us to identify proteins with distinct localisation to the glomeruli (n=11), proximal tubules (n=120), distal tubules (n=9) or collecting ducts (n=8). Among the identified kidney elevated transcripts, we found several proteins not previously characterised or identified as elevated in kidney. This description of the kidney specific transcriptome and proteome provides a resource for basic and clinical research to facilitate studies to understand kidney biology and disease.
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| 39. |
- Hedenström, Mattias, et al.
(författare)
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Visualization and interpretation of OPLS models based on 2D NMR Data
- 2008
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Ingår i: Chemometrics and Intelligent Laboratory Systems. - : Elsevier. - 0169-7439 .- 1873-3239. ; 92:2, s. 110-117
-
Tidskriftsartikel (refereegranskat)abstract
- Multivariate analysis on spectroscopic 1H NMR data is well established in metabolomics and other fields where the composition of complex samples is studied. However, biomarker identification can be hampered by overlapping resonances. 2D NMR data provides a more detailed “fingerprint” of the chemical structure and composition of the sample with greatly improved spectral resolution compared to 1H NMR data. In this report, we demonstrate a procedure for the construction of multivariate models based on frequency domain 2D NMR data where the loadings can be visualized as highly informative 2D loading spectra. This method is based on the analysis of raw spectral data without any need for peak picking or integration prior to analysis. Spectral features such as line widths and peak positions are thus retained. Hence, the loadings can be visualized and interpreted on a molecular level as pseudo 2D spectra in order to identify potential biomarkers. To demonstrate this strategy we have analyzed HSQC spectra acquired from populus phloem plant extracts originating from a set of designed experiments with OPLS regression.
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| 40. |
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| 41. |
- Häggström, Carola, et al.
(författare)
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Knowledge Retention and Changes in Licensed Chainsaw Workers’ risk awareness
- 2023
-
Ingår i: Small-Scale Forestry. - : Springer Science and Business Media LLC. - 1873-7617 .- 1873-7854. ; 22, s. 103-119
-
Tidskriftsartikel (refereegranskat)abstract
- Work with chainsaws is hazardous and felling trees is the activity with the highest risks for injuries and fatalities. While industrial forestry is increasingly mechanized, manual felling is still the main work method for private, small-scale forest owners. During this work, the workers' safety heavily depends on their skill and safe practice, so training is presumably important for preventing injuries and reducing fatalities. Unfortunately, private forest owners have been difficult to reach with this kind of safety intervention. Moreover, target chainsaw users are not likely to repeat the training very frequently. Hence, the training must both be effective and be so for many years to come. This paper addresses the knowledge retention and self-reported changes in behaviour of 682 chainsaw users who passed the exam for the Swedish chainsaw licence 1, 3, 5, 7 or 9 years previously. Acquisition of the licence resulted in a strong increase in 98% of the participants' risk awareness and safe work practices. Less than half (45%) of the participants passed a re-test equivalent to the theoretical examination for the chainsaw licence. Private forest owners performed somewhat better than employees did. The main indicator of retained knowledge of safe chainsaw handling was frequency of practice the previous year. After one year, the test results did not deteriorate with additional time. Based on those results, the best practice is to ensure regular usage of the chainsaw and refresher training when the chainsaw has not been used for a year.
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| 42. |
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| 43. |
- Johansson, Björn, et al.
(författare)
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Release Rates for Pine Sawfly Pheromones from Two Types of Dispensers and Phenology of Neodiprion sertifer
- 2001
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Ingår i: Journal of Chemical Ecology. - 0098-0331 .- 1573-1561. ; 27:4, s. 733-745
-
Tidskriftsartikel (refereegranskat)abstract
- Comparisons of release rates, duration in the field, and catch efficiency of polyethylene and cotton roll dispensers for the sex pheromones of sawflies (Hymenoptera: Diprionidae) were conducted. The release rates of the Neodiprion sertifer (Geoffr.) and Diprion pini (L.) sex pheromones, the acetates of pentadecanol and (2S,3S,7S)-3,7-dimethyl (2S,3R,7R)-3,7-dimethyl-2-tridecanol from polyethylene dispensers were measured at different temperatures in the laboratory. The release rates for the substances depended on both the temperature and initial load in the vials. The catch from cotton rolls baited with 100 μg of the acetate or propionate of 3,7-dimethyl-2-pentadecanol was compared to the catch from regularly renewed cotton rolls baited with 10 μg of the same acetate. The catch was higher for the 100-μg cotton rolls for, at most, 45 days, and there was no significant difference in catch between the acetate and the propionate. The catch in traps baited with polyethylene or cotton roll dispensers loaded with the acetate of 3,7-dimethyl-2-pentadecanol was compared and showed that cotton roll traps mirrored the decreasing release of the substance rather than the actual flight activity. The length of the flight period of N. sertifer in Sweden, the Czech Republic, Italy, and Greece did not exceed 100 days in any of the countries. By adjusting the initial pheromone load of the polyethylene vials to the expected temperatures, it should be possible to get a constant and sufficiently high release rate during the entire flight period.
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| 44. |
- Kampf, Caroline, et al.
(författare)
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The human liver-specific proteome defined by transcriptomics and antibody-based profiling
- 2014
-
Ingår i: FASEB Journal. - : Wiley. - 1530-6860 .- 0892-6638. ; 28:7, s. 2901-2914
-
Tidskriftsartikel (refereegranskat)abstract
- Human liver physiology and the genetic etiology of the liver diseases can potentially be elucidated through the identification of proteins with enriched expression in the liver. Here, we combined data from RNA sequencing (RNA-Seq) and antibody-based immunohistochemistry across all major human tissues to explore the human liver proteome with enriched expression, as well as the cell type-enriched expression in hepatocyte and bile duct cells. We identified in total 477 protein-coding genes with elevated expression in the liver: 179 genes have higher expression as compared to all the other analyzed tissues; 164 genes have elevated transcript levels in the liver shared with at least one other tissue type; and an additional 134 genes have a mild level of increased expression in the liver. We identified the precise localization of these proteins through antibody-based protein profiling and the subcellular localization of these proteins through immunofluorescent-based profiling. We also identified the biological processes and metabolic functions associated with these proteins, investigated their contribution in the occurrence of liver diseases, and identified potential targets for their treatment. Our study demonstrates the use of RNA-Seq and antibody-based immunohistochemistry for characterizing the human liver proteome, as well as the use of tissue-specific proteins in identification of novel drug targets and discovery of biomarkers.
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| 45. |
- Kilbo Edlund, Karl, et al.
(författare)
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Long-term exposure to air pollution, coronary artery calcification, and carotid artery plaques in the population-based Swedish SCAPIS Gothenburg cohort.
- 2022
-
Ingår i: Environmental research. - : Elsevier BV. - 1096-0953 .- 0013-9351. ; 214:Pt 2
-
Tidskriftsartikel (refereegranskat)abstract
- Long-term exposure to air pollution is associated with cardiovascular events. A main suggested mechanism is that air pollution accelerates the progression of atherosclerosis, yet current evidence is inconsistent regarding the association between air pollution and coronary artery and carotid artery atherosclerosis, which are well-established causes of myocardial infarction and stroke. We studied associations between low levels of long-term air pollution, coronary artery calcium (CAC) score, and the prevalence and area of carotid artery plaques, in a middle-aged population-based cohort. The Swedish CArdioPulmonary bioImage Study (SCAPIS) Gothenburg cohort was recruited during 2013-2017 and thoroughly examined for cardiovascular risk factors, including computed tomography of the heart and ultrasonography of the carotid arteries. In 5070 participants (age 50-64 years), yearly residential exposures to air pollution (PM2.5, PM10, PMcoarse, NOx, and exhaust-specific PM2.5 1990-2015) were estimated using high-resolution dispersion models. We used Poisson regression to examine associations between long-term (26 years' mean) exposure to air pollutants and CAC score, and prevalence of carotid artery plaques, adjusted for potential confounders. Among participants with carotid artery plaques, we also examined the association with plaque area using linear regression. Mean exposure to PM2.5 was low by international standards (8.5μg/m3). There were no consistent associations between long-term total PM2.5 exposure and CAC score or presence of carotid artery plaques, but an association between total PM2.5 and larger plaque area in participants with carotid plaques. Associations with traffic-related air pollutants were consistently positive for both a high CAC score and bilateral carotid artery plaques. These associations were independent of road traffic noise. We found stronger associations among men and participants with cardiovascular risk factors. The results lend some support to atherosclerosis as a main modifiable pathway between low levels of traffic-related ambient air pollution and cardiovascular disease, especially in vulnerable individuals.
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| 46. |
- Kronholm, Thomas, et al.
(författare)
-
Implementering av skyddsbågar på fyrhjulingar : en utvärdering av användares erfarenheter av ett vältskydd
- 2023
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Intresset för fyrhjulingar har ökat under de senaste åren och fyrhjulingen är idag ett frekvent använt arbets- och nöjesfordon i Sverige. Enbart under år 2021 registrerades 12 000 nya fyrhjulingar i Sverige. Med en mer utbredd användning av fyrhjulingar så har också antalet allvarliga olyckor och dödsfall i samband med fyrhjulingskörning ökat. Trafikverket, försäkringsbolag, skogsföretag, forskare och en del branschorganisationer har under de senaste åren därför initierat flera projekt och insatser i syfte att öka säkerheten och minska antalet omkomna och skadade fyrhjulingsanvändare. En säkerhetshöjande åtgärd som återkommande lyfts fram i forskningen är att utrusta fyrhjulingen med ett vältskydd, en så kallad skyddsbåge, som skyddar föraren vid vältningsolyckor. Vid en vältningsolycka riskerar föraren att hamna i kläm under maskinen, men med ett vältskydd som hindrar maskinen från att rulla runt så minskar denna risk betydligt. I vissa länder, t.ex. Australien, finns idag krav på att fyrhjulingar skall vara utrustade med någon typ av vältskydd. I Sverige har intresset för att utrusta fyrhjulingen med vältskydd hittills varit begränsat. En del studier har pekat på att det både bland förare och tillverkare har funnits ett motstånd mot implementering av vältskydd, bl.a. på grund av en oro för att det skulle vara hindrande för normal användning.Det övergripande syftet med detta projekt har varit att kartlägga och beskriva erfarenheterna från en stor grupp med användare av fyrhjuling med vältskydd och därigenom öka säkerheten och det allmänna medvetandet om nyttan med vältskydd på fyrhjulingar. En målsättning är att detta arbete kan skynda på utvecklingen av säkerheten för fyrhjulingar och på sikt leda till en storskalig implementering av vältskydd i Sverige, i likhet med den utveckling som redan skett i andra länder.För kunna samla in erfarenheter från fyrhjulingsanvändare med vältskydd så importerades vältskydd av märket Quadbar från Australien och distribuerades till ca 50 personer som hade anmält intresse att montera ett vältskydd på sin fyrhjuling och därefter dela med sig av sina synpunkter och erfarenheter. Dessa synpunkter samlades in vid tre olika enkättillfällen. Den första enkäten gjordes inför monteringen av vältskyddet, den andra efter en kortare tids användning och den sista drygt ett år efter att vältskyddet hade monterats. Den första enkäten besvarades av 50 deltagare, den andra av 38, och den sista enkäten besvarades av 37 deltagare.De vanligaste farhågorna inför projektet var att vältskyddet skulle påverka körningen och framkomligheten, eller att det skulle vara hindrande för transporter. Exempelvis att det kan fastna i låg hängande grenar eller liknande och därmed orsaka en olycka. Andra farhågor var att det skulle vara hindrande för användningen av vissa redskap, så som vinsch eller släp. Ur ett säkerhetsperspektiv var deltagarna generellt positivt inställda till vältskyddet.En stor majoritet av deltagarna använde normalt sin fyrhjuling till transporter av material, person och utrustning i skogsbruket, eller till transporter på gården. Färre än hälften använde den normalt till nöjesåkning. De vanligaste terrängtyperna som fyrhjulingen framfördes i var skogsmark, enskild väg, traktorväg och jordbruksmark. En mindre andel av deltagarna framförde i normala fall fyrhjulingen på allmän väg. Det var mycket vanligt att fyrhjulingen kördes tillsammans med ett tillkopplat släp som saknade bromsar. Drygt hälften av deltagarna transporterade även last på fyrhjulingens bakre eller främre lastbåge.Under testperioden var ca 20 % av deltagarna med om en olycka eller incident med sin fyrhjuling. Totalt inrapporterades tio olyckor eller incidenter. Vid de vältningsolyckor som inträffat hade vältskyddet fungerat som det var tänkt och haft en positiv inverkan på utfallet, enligt de beskrivningar som deltagarna har lämnat. Vid några av de mindre allvarliga incidenterna hade förarna av ovana eller oaktsamhet missbedömt den nya höjden på ekipaget eller glömt bort att de Sammanfattning hade vältskyddet bakom ryggen, vilket hade lett till att vältskyddet hade tagit i när de kört under låga passager (t.ex. en klädlina). Inga personskador har inrapporterats i samband med incidenterna.Deltagarna var generellt nöjda med den vältskydd de hade haft, vilket framgår av att en stor andel uttryckte att det var troligt eller mycket troligt att de skulle rekommendera Quadbar till sina bekanta. Resultaten visar också att deltagarnas säkerhetskänsla ökade med vältskyddet monterad på fyrhjulingen. Detta gällde både för deras egen och för andra förares säkerhet. Deras trygghetskänsla ökade över tid.De mest vanliga bekymren som en del deltagare hade upplevt var att det aktuella vältskyddets infästning försämrade möjligheten att koppla till släpp på fyrhjulingen, samt att det försvårade användningen av vinsch. Den medföljande dragkroksförlängaren ansågs i vissa fall ha för dålig hållfasthet. Några deltagare hade därför gjort modifieringar på vältskyddet, dess infästning, eller något tillbehör till denna för att kunna nyttja fyrhjulingen enligt sina egna behov. Att vältskyddet gjorde ekipaget högre försvårade också transport av fyrhjulingen på släp med kåpa. Flera deltagare efterlyste därför en smidigare lösning för att tillfälligt kunna plocka av eller vika ner vältskyddet. Liknande önskemål hade de som ville kunna använda vinsch eller för att komma åt förvaringsutrymmen som annars blockerades av vältskyddet.En av studiens slutsatser är att vältskyddet generellt verkar ha fungerat bra för de flesta av deltagarna, och användningen av vältskydd kan öka både den upplevda och den faktiska säkerheten vid fyrhjulingsanvändning. Deltagarnas positiva inställning till att rekommendera vältskyddet till bekanta kan antas bidra till ett ökat intresse hos fler att införskaffa denna eller liknande vältskydd. Projektet har också synliggjort vad som särskilt behöver utvecklas för att just Quadbar ska bli ännu bättre lämpad för fyrhjulingsanvändare som främst nyttjar den i skogsbruket.
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| 47. |
- Landsiedel, Christian, et al.
(författare)
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Syllabification of conversational speech using bidirectional long-short-term memory neural networks
- 2011
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Ingår i: Acoustics, Speech and Signal Processing (ICASSP), 2011 IEEE International Conference on. - Prague, Czech Republic. ; , s. 5256-5259
-
Konferensbidrag (refereegranskat)abstract
- Segmentation of speech signals is a crucial task in many types of speech analysis. We present a novel approach at segmentation on a syllable level, using a Bidirectional Long-Short-Term Memory Neural Network. It performs estimation of syllable nucleus positions based on regression of perceptually motivated input features to a smooth target function. Peak selection is performed to attain valid nuclei positions. Performance of the model is evaluated on the levels of both syllables and the vowel segments making up the syllable nuclei. The general applicability of the approach is illustrated by good results for two common databases - Switchboard and TIMIT - for both read and spontaneous speech, and a favourable comparison with other published results.
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| 48. |
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| 49. |
- Lindman, Björn, et al.
(författare)
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The relevance of structural features of cellulose and its interactions to dissolution, regeneration, gelation and plasticization phenomena
- 2017
-
Ingår i: Physical Chemistry Chemical Physics. - : Royal Society of Chemistry (RSC). - 1463-9076 .- 1463-9084. ; 19:35, s. 23704-23718
-
Forskningsöversikt (refereegranskat)abstract
- Cellulose is the most abundant polymer and a very important renewable resource. Since cellulose cannot be shaped by melting, a major route for its use for novel materials, new chemical compounds and renewable energy must go via the solution state. Investigations during several decades have led to the identification of several solvents of notably different character. The mechanisms of dissolution in terms of intermolecular interactions have been discussed from early work but, even on fundamental aspects, conflicting and opposite views appear. In view of this, strategies for developing new solvent systems for various applications have remained obscure. There is for example a strong need for using forest products for higher value materials and for environmental and cost reasons to use water-based solvents. Several new water-based solvents have been developed recently but there is no consensus regarding the underlying mechanisms. Here we wish to address the most important mechanisms described in the literature and confront them with experimental observations. A broadened view is helpful for improving the current picture and thus cellulose derivatives and phenomena such as fiber dissolution, swelling, regeneration, plasticization and dispersion are considered. In addition to the matter of hydrogen bonding versus hydrophobic interactions, the role of ionization as well as some applications of new knowledge gained are highlighted.
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| 50. |
- Lindman, Björn, et al.
(författare)
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The relevance of structural features of cellulose and its interactions to dissolution, regeneration, gelation and plasticization phenomena
- 2017
-
Ingår i: Physical Chemistry, Chemical Physics - PCCP. - 1463-9076 .- 1463-9084. ; 19:35, s. 23704-23718
-
Tidskriftsartikel (refereegranskat)abstract
- Cellulose is the most abundant polymer and a very important renewable resource. Since cellulose cannot be shaped by melting, a major route for its use for novel materials, new chemical compounds and renewable energy must go via the solution state. Investigations during several decades have led to the identification of several solvents of notably different character. The mechanisms of dissolution in terms of intermolecular interactions have been discussed from early work but, even on fundamental aspects, conflicting and opposite views appear. In view of this, strategies for developing new solvent systems for various applications have remained obscure. There is for example a strong need for using forest products for higher value materials and for environmental and cost reasons to use water-based solvents. Several new water-based solvents have been developed recently but there is no consensus regarding the underlying mechanisms. Here we wish to address the most important mechanisms described in the literature and confront them with experimental observations. A broadened view is helpful for improving the current picture and thus cellulose derivatives and phenomena such as fiber dissolution, swelling, regeneration, plasticization and dispersion are considered. In addition to the matter of hydrogen bonding versus hydrophobic interactions, the role of ionization as well as some applications of new knowledge gained are highlighted.
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