| 1. |
- Krawczyk, M., et al.
(författare)
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Liver Transplantation for Hepatic Trauma: A Study From the European Liver Transplant Registry
- 2016
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Ingår i: Transplantation. - : Ovid Technologies (Wolters Kluwer Health). - 0041-1337. ; 100:11, s. 2372-2381
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Tidskriftsartikel (refereegranskat)abstract
- Background. Liver transplantation is the most extreme form of surgical management of patients with hepatic trauma, with very limited literature data supporting its use. The aim of this study was to assess the results of liver transplantation for hepatic trauma. Methods. This retrospective analysis based on European Liver Transplant Registry comprised data of 73 recipients of liver transplantation for hepatic trauma performed in 37 centers in the period between 1987 and 2013. Mortality and graft loss rates at 90 days were set as primary and secondary outcome measures, respectively. Results. Mortality and graft loss rates at 90 days were 42.5% and 46.6%, respectively. Regarding general variables, cross-clamping without extracorporeal veno-venous bypass was the only independent risk factor for both mortality (P = 0.031) and graft loss (P = 0.034). Regarding more detailed factors, grade of liver trauma exceeding IV increased the risk ofmortality (P = 0.005) and graft loss (P = 0.018). Moreover, a tendency above the level of significance was observed for the negative impact of injury severity score (ISS) onmortality (P = 0.071). The optimal cutoff for ISS was 33, with sensitivity of 60.0%, specificity of 80.0%, positive predictive value of 75.0%, and negative predictive value of 66.7%. Conclusions. Liver transplantation seems to be justified in selected patients with otherwise fatal severe liver injuries, particularly in whom cross-clamping without extracorporeal bypass can be omitted. The ISS cutoff less than 33 may be useful in the selection process.
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| 2. |
- Cesar de Freitas, Artur, et al.
(författare)
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Effects of aluminum distearate addition on UO2 sintering and microstructure
- 2022
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Ingår i: Progress in nuclear energy (New series). - : Elsevier BV. - 0149-1970 .- 1878-4224. ; 153, s. 104440-104440
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Tidskriftsartikel (refereegranskat)abstract
- Uranium dioxide (UO2) is widely used as a fuel in commercial nuclear light-water reactors (LWRs). Rigorous control of density, pore, and grain size of UO2 pellets are important prerequisites for fuel performance. Solid lubricants, frequently used in pellets manufacturing, minimize structural defects on compaction such as cracks and end-capping, promoting grain growth during sintering. This work presents and discusses the effects of the aluminum distearate (ADS) addition on the sintering behavior and microstructure of UO2 fuel pellets. UO2 and UO2-0.2wt% ADS pellets were sintered at 1760 °C for 5.7 h for comparison purposes. The results show that the densification rate increases using the solid lubricant, but the shrinkage is lowered by 0.7% due to low homogenization. The average grain size was increased by about 35% during sintering. Based on our results and a literature review, a mechanism for grain growth by aluminum addition is proposed.
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