SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Ericsson Peter) "

Sökning: WFRF:(Ericsson Peter)

  • Resultat 1-50 av 117
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Bangsbo, Jens, et al. (författare)
  • The Copenhagen Consensus Conference 2016 : children, youth, and physical activity in schools and during leisure time
  • 2016
  • Ingår i: British Journal of Sports Medicine. - : BMJ Publishing Group Ltd. - 0306-3674 .- 1473-0480. ; 50:19, s. 1177-1178
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • From 4 to 7 April 2016, 24 researchers from 8 countries and from a variety of academic disciplines gathered in Snekkersten, Denmark, to reach evidence-based consensus about physical activity in children and youth, that is, individuals between 6 and 18 years. Physical activity is an overarching term that consists of many structured and unstructured forms within school and out-of-school-time contexts, including organised sport, physical education, outdoor recreation, motor skill development programmes, recess, and active transportation such as biking and walking. This consensus statement presents the accord on the effects of physical activity on children's and youth's fitness, health, cognitive functioning, engagement, motivation, psychological well-being and social inclusion, as well as presenting educational and physical activity implementation strategies. The consensus was obtained through an iterative process that began with presentation of the state-of-the art in each domain followed by plenary and group discussions. Ultimately, Consensus Conference participants reached agreement on the 21-item consensus statement.
  •  
2.
  • Ericsson, Peter, et al. (författare)
  • ECL Cell Histamine Mobilization Studied byGastric Submucosal Microdialysis in Awake Rats:Methodological Considerations.
  • 2003
  • Ingår i: Pharmacology and Toxicology. - : Wiley. - 1600-0773 .- 0901-9928. ; 93:2, s. 57-65
  • Tidskriftsartikel (refereegranskat)abstract
    • The ECL cells are endocrine/paracrine cells in the acid-producing part of the stomach. They secrete histamine in response to circulating gastrin. Gastric submucosal microdialysis has been used to study ECL-cell histamine mobilization in awake rats. In the present study we assess the usefulness and limitations of the technique. Microdialysis probes were implanted in the gastric submucosa. Histological analysis of the stomach wall around the probe revealed a moderate, local inflammatory reaction 1-2 days after implantation; the inflammation persisted for at least 10 days. Experiments were conducted 3 days after the implantation. The "true" submucosal histamine concentration was determined by perfusing at different rates (the zero flow method) or with different concentrations of histamine at a constant rate (the no-net-flux method): in fasted rats it was calculated to be 87±5 (means±S.E.M.) nmol/l and 76±9 nmol/l, respectively. The corresponding histamine concentrations in fed rats were 93±5 and 102±8 nmol/l, respectively. With a perfusion rate of 74 mul/hr the recovery of submucosal histamine was 49%, at 34 mul/hr the recovery increased to 83%. At a perfusion rate below 20 mul/hr the microdialysate histamine concentration was close to the actual concentration in the submucosa. The ECL-cell histamine mobilization was independent of the concentrations of Ca2+ in the perfusion medium (0-3.4 mmol/l Ca2+). In one experiment, histamine mobilization in response to gastrin (10 nmol/kg/hr subcutaneously) was monitored in rats pretreated with prednisolone (60 mg/kg) or indomethacin (15 mg/kg). The two antiinflammatory agents failed to affect the concentration of histamine in the microdialysate either before or during the gastrin challenge, which was in accord with the observation that the inflammatory reaction was modest and that inflammatory cells were relatively few around the probe and in the wall of the probe. In another experiment, rats were given aminoguanidine (10 mg/kg) or metoprine (10 mg/kg) 4 hr before the start of gastrin infusion (5 nmol/kg/hr intravenously). Metoprine (inhibitor of histamine N-methyl transferase) did not affect the microdialysate histamine concentration, while aminoguanidine (inhibitor of diamine oxidase) raised both basal and gastrin-stimulated histamine concentrations. We conclude that microdialysis can be used to monitor changes in the concentration of histamine in the submucosa of the stomach, and that the inflammatory reaction to the probe is moderate and does not affect the submucosal histamine mobilization.
  •  
3.
  • Forsberg, Fredrik, et al. (författare)
  • CMOS-integrated Si/SiGe quantum-well infrared microbolometer focal plane arrays manufactured with very large-scale heterogeneous 3-d integration
  • 2015
  • Ingår i: IEEE Journal of Selected Topics in Quantum Electronics. - : Institute of Electrical and Electronics Engineers Inc.. - 0792-1233 .- 1077-260X .- 1558-4542. ; 21:4
  • Tidskriftsartikel (refereegranskat)abstract
    • We demonstrate infrared focal plane arrays utilizing monocrystalline silicon/silicon-germanium (Si/SiGe) quantum-well microbolometers that are heterogeneously integrated on top of CMOS-based electronic read-out integrated circuit substrates. The microbolometers are designed to detect light in the long wavelength infrared (LWIR) range from 8 to 14 μm and are arranged in focal plane arrays consisting of 384 × 288 microbolometer pixels with a pixel pitch of 25 μm × 25 μm. Focal plane arrays with two different microbolometer designs have been implemented. The first is a conventional single-layer microbolometer design and the second is an umbrella design in which the microbolometer legs are placed underneath the microbolometer membrane to achieve an improved pixel fill-factor. The infrared focal plane arrays are vacuum packaged using a CMOS compatible wafer bonding and sealing process. The demonstrated heterogeneous 3-D integration and packaging processes are implemented at wafer-level and enable independent optimization of the CMOS-based integrated circuits and the microbolometer materials. All manufacturing is done using standard semiconductor and MEMS processes, thus offering a generic approach for integrating CMOS-electronics with complex miniaturized transducer elements
  •  
4.
  •  
5.
  • Karell, Patrik, et al. (författare)
  • Mammalian nest predation induces small-scale nest site switching in territorial tawny owl (Strix aluco) females
  • 2020
  • Ingår i: Ornis Fennica. - 0030-5685. ; 97:2, s. 45-52
  • Tidskriftsartikel (refereegranskat)abstract
    • Nest predation is a major factor affecting fitness in birds. Individuals are expected to respond to nest predation by selecting safe nesting sites and by moving away from risky sites. Thereby, perceived risk or experience of predation should lead to shifts in nest site selection. Experimental studies on behavioural and life-history consequences of nest predation have traditionally manipulated the risk of predation and studied the immediate consequences thereof. Fewer studies have however analysed the behavioural consequences of perceived predation risk to future breeding events and we know little about how sedentary territorial species respond to nest predation. We experimentally manipulated tawny owl (Strix aluco) breeding nest site choice by providing an additional alternative nest box within the territory, nearby the original nesting sites. The new nest box was provided either after a successful reproductive event (control group), or following a failed reproductive event caused by a nest predator (i.e. pine marten Martes martes, predated group). We show that tawny owls generally switched to the alternative nest site in the current breeding season when the nest was predated in the previous year, whereas they used the same nest after a successful breeding. We found no effects of previous predation experience on the probability to breed nor on clutch size. We conclude that small scale movement within the territory are used by tawny owls to minimize predation risk and that the owls use information on past predation events and nest failure to optimize their breeding decision in the following season.
  •  
6.
  • Kolmert, Johan, et al. (författare)
  • Urinary Leukotriene E-4 and Prostaglandin D-2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation A Clinical Observational Study
  • 2021
  • Ingår i: American Journal of Respiratory and Critical Care Medicine. - NEW YORK, USA : AMER THORACIC SOC. - 1073-449X .- 1535-4970. ; 203:1, s. 37-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Rationale: New approaches are needed to guide personalized treatment of asthma. Objectives: To test if urinary eicosanoid metabolites can direct asthma phenotyping. Methods: Urinary metabolites of prostaglandins (PGs), cysteinyl leukotrienes (CysLTs), and isoprostanes were quantified in the U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Diseases Outcomes) study including 86 adults with mild-to-moderate asthma (MMA), 411 with severe asthma (SA), and 100 healthy control participants. Validation was performed internally in 302 participants with SA followed up after 12-18 months and externally in 95 adolescents with asthma. Measurement and Main Results: Metabolite concentrations in healthy control participants were unrelated to age, body mass index, and sex, except for the PGE(2) pathway. Eicosanoid concentrations were generally greater in participants with MMA relative to healthy control participants, with further elevations in participants with SA. However, PGE(2) metabolite concentrations were either the same or lower in male nonsmokers with asthma than in healthy control participants. Metabolite concentrations were unchanged in those with asthma who adhered to oral corticosteroid treatment as documented by urinary prednisolone detection, whereas those with SA treated with omalizumab had lower concentrations of LTE4 and the PGD(2) metabolite 2,3-dinor-11 beta-PGF(2 alpha). High concentrations of LTE4 and PGD(2) metabolites were associated with lower lung function and increased amounts of exhaled nitric oxide and eosinophil markers in blood, sputum, and urine in U-BIOARED participants and in adolescents with asthma. These type 2 (T2) asthma associations were reproduced in the follow-up visit of the U-BIOPRED study and were found to be as sensitive to detect T2 inflammation as the established biomarkers. Conclusions: Monitoring of urinary eicosanoids can identify T2 asthma and introduces a new noninvasive approach for molecular phenotyping of adult and adolescent asthma.
  •  
7.
  • Yasinska, Valentyna, et al. (författare)
  • Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids
  • 2023
  • Ingår i: ERJ Open Research. - : European Respiratory Society. - 2312-0541. ; 9:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Rationale: Patients with severe asthma are dependent upon treatment with high doses of inhaled corticosteroids (ICS) and often also oral corticosteroids (OCS). The extent of endogenous androgenic anabolic steroid (EAAS) suppression in asthma has not previously been described in detail. The objective of the present study was to measure urinary concentrations of EAAS in relation to exogenous corticosteroid exposure.Methods: Urine collected at baseline in the U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease outcomes) study of severe adult asthmatics (SA, n=408) was analysed by quantitative mass spectrometry. Data were compared to that of mild-to-moderate asthmatics (MMA, n=70) and healthy subjects (HC, n=98) from the same study.Measurements and main results: The concentrations of urinary endogenous steroid metabolites were substantially lower in SA than in MMA or HC. These differences were more pronounced in SA patients with detectable urinary OCS metabolites. Their dehydroepiandrosterone sulfate (DHEA-S) concentrations were <5% of those in HC, and cortisol concentrations were below the detection limit in 75% of females and 82% of males. The concentrations of EAAS in OCS-positive patients, as well as patients on high-dose ICS only, were more suppressed in females than males (p<0.05). Low levels of DHEA were associated with features of more severe disease and were more prevalent in females (p<0.05). The association between low EAAS and corticosteroid treatment was replicated in 289 of the SA patients at follow-up after 12–18 months.Conclusion: The pronounced suppression of endogenous anabolic androgens in females might contribute to sex differences regarding the prevalence of severe asthma.
  •  
8.
  •  
9.
  • Andersson, Emelie, et al. (författare)
  • Costs of diabetes complications : hospital-based care and absence from work for 392,200 people with type 2 diabetes and matched control participants in Sweden
  • 2020
  • Ingår i: Diabetologia. - : Springer. - 0012-186X .- 1432-0428. ; 63:12, s. 2582-2594
  • Tidskriftsartikel (refereegranskat)abstract
    • AIMS/HYPOTHESIS: The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital-based healthcare (inpatient and outpatient care) and work absence related to individual macrovascular and microvascular complications of type 2 diabetes in Sweden in 2016.METHODS: Data for 2016 were retrieved from a Swedish national retrospective observational database cross-linking individual-level data for 1997-2016. The database contained information from population-based health, social insurance and socioeconomic registers for 392,200 people with type 2 diabetes and matched control participants (5:1). Presence of type 2 diabetes and of diabetes complications were derived using all years, 1997-2016. Costs of hospital-based care and of absence from work due to diabetes complications were estimated for the year 2016. Regression analysis was used for comparison with control participants to attribute absence from work to individual complications, and to account for joint presence of complications.RESULTS: Use of hospital care for complications was higher in type 2 diabetes compared with control participants in 2016: 26% vs 12% had ≥1 hospital contact; there were 86,104 vs 24,608 outpatient visits per 100,000 people; and there were 9894 vs 2546 inpatient admissions per 100,000 people (all p < 0.001). The corresponding total costs of hospital-based care for complications were €919 vs €232 per person (p < 0.001), and 74.7% of costs were then directly attributed to diabetes (€687 per person). Regression analyses distributed the costs of days absent from work across diabetes complications per se, basic type 2 diabetes effect and unattributed causes. Diabetes complications amounted to €1317 per person in 2016, accounting for possible complex interactions (25% of total costs of days absent). Key drivers of costs were the macrovascular complications angina pectoris, heart failure and stroke; and the microvascular complications eye diseases, including retinopathy, kidney disease and neuropathy. Early mortality in working ages cost an additional €579 per person and medications used in risk-factor treatment amounted to €418 per person.CONCLUSIONS/INTERPRETATION: The economic burden of complications in type 2 diabetes is substantial. Costs of absence from work in this study were found to be greater than of hospital-based care, highlighting the need for considering treatment consequences in a societal perspective in research and policy. Graphical abstract.
  •  
10.
  •  
11.
  • Ansari, Shaquib Rahman, et al. (författare)
  • Pharmaceutical Quality by Design Approach to Develop High-Performance Nanoparticles for Magnetic Hyperthermia
  • 2024
  • Ingår i: ACS Nano. - 1936-0851 .- 1936-086X. ; 18:23, s. 15284-15302
  • Tidskriftsartikel (refereegranskat)abstract
    • Magnetic hyperthermia holds significant therapeutic potential, yet its clinical adoption faces challenges. One obstacle is the large-scale synthesis of high-quality superparamagnetic iron oxide nanoparticles (SPIONs) required for inducing hyperthermia. Robust and scalable manufacturing would ensure control over the key quality attributes of SPIONs, and facilitate clinical translation and regulatory approval. Therefore, we implemented a risk-based pharmaceutical quality by design (QbD) approach for SPION production using flame spray pyrolysis (FSP), a scalable technique with excellent batch-to-batch consistency. A design of experiments method enabled precise size control during manufacturing. Subsequent modeling linked the SPION size (6–30 nm) and composition to intrinsic loss power (ILP), a measure of hyperthermia performance. FSP successfully fine-tuned the SPION composition with dopants (Zn, Mn, Mg), at various concentrations. Hyperthermia performance showed a strong nonlinear relationship with SPION size and composition. Moreover, the ILP demonstrated a stronger correlation to coercivity and remanence than to the saturation magnetization of SPIONs. The optimal operating space identified the midsized (15–18 nm) Mn0.25Fe2.75O4 as the most promising nanoparticle for hyperthermia. The production of these nanoparticles on a pilot scale showed the feasibility of large-scale manufacturing, and cytotoxicity investigations in multiple cell lines confirmed their biocompatibility. In vitro hyperthermia studies with Caco-2 cells revealed that Mn0.25Fe2.75O4 nanoparticles induced 80% greater cell death than undoped SPIONs. The systematic QbD approach developed here incorporates process robustness, scalability, and predictability, thus, supporting the clinical translation of high-performance SPIONs for magnetic hyperthermia.
  •  
12.
  • Bach-Gansmo, T, et al. (författare)
  • Motion associated susceptibility artifacts
  • 1992
  • Ingår i: Acta Radiologica. - 1600-0455. ; 33:6, s. 606-610
  • Tidskriftsartikel (refereegranskat)abstract
    • A bowel labeling agent is important for improving abdominal MR. Besides providing contrast between the bowel and other organs, the contrast agent itself is a potential source of artifacts. The artifacts created by superparamagnetic particles (SPP) subjected to motion have been studied in vitro at 0.5 T, and compared to artifacts created by a paramagnetic compound. Apart from the expected static effects of the SPP, movement induced additional artifacts were seen as signal displacements in the phase-encoding direction. The artifacts were obvious at an iron concentration of 1 mg Fe/ml, barely visible at 0.2 mg Fe/ml, and completely absent at 0.1 mg Fe/ml. Artifacts were also evident with the SPP outside the imaging slice. This further emphasizes the importance of choosing the lowest effective dose when using SPP contrast agents. For the paramagnetic agent, motion propagated artifacts consisted of high and low signal regions in a mosaic pattern.
  •  
13.
  • Banér, Johan, et al. (författare)
  • Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes
  • 2007
  • Ingår i: Journal of Virological Methods. - : Elsevier BV. - 0166-0934 .- 1879-0984. ; 143:2, s. 200-206
  • Tidskriftsartikel (refereegranskat)abstract
    • The World Organization for Animal Health (Office International des Epizooties, OIE) includes the diseases caused by foot-and-mouth disease virus (FMDV), swine vesicular disease virus (SVDV), and vesicular stomatitis virus (VSV), as "Diseases Notifiable to the OIE". Foot-and-mouth disease (FMD) outbreaks have severe economical as well as social effects and cannot be differentiated from the diseases caused by the other two viruses on the basis of clinical symptoms. Efficient laboratory techniques are therefore required for detection and identification of the viruses causing similar vesicular symptoms in swine. A rapid method is described using padlock probes and microarrays to detect simultaneously and differentiate the three viruses in a single reaction, as well as providing serotype information in cases of VSV infection. The padlock probe/microarray assay detected successfully and identified 39 cDNA samples of different origin representing the three viruses. The results were in complete agreement with identities and serotypes determined previously. This novel virus detection method is discussed in terms of usefulness and further development.
  •  
14.
  • Bauer, Peter, 1992- (författare)
  • När slutar invandrarna vandra? : Integrationsfrågan i statlig, kommunal och skolpolitisk diskurs 1967–2000
  • 2023
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • During the last three decades of the 20th century Swedish immigrant policy went through a profound change. In the late 1960s immigrant policy were based on assimilation but during the 1970’s and 1980’s this policy was exchanged to multicultural guidelines. These multicultural guidelines were however abandoned in the late 1990s when integration became a key word in the debate about immigrants.  This thesis investigates how these changes were made possible by a shifting understanding of immigrants in state and local discourse (the last represented by Malmö municipality) by operationalizing Carol Lee Bacchis What’s the problem represented to be analysis.  Previous research has shown that the social category of immigrants during the first six decades of the 20th century understood immigrants as a threat towards the Swedish race and later the welfare state. From this perspective immigrant policy can be seen as the result of the creation of a problematized immigrant subject, a tendency that is also the case for later decades. The investigation shows that immigrants in the early 1970’s were mainly understood from a class and welfare perspective. During this period immigrants were seen as a threat towards the social cohesion of the welfare state as well as the social democratic ambitions of a raised standard of living for the working class. This understanding led to the development of a multicultural policy where immigrant culture was supported within state and local politics and by structural changes in the education system, aiming to include the category in civic life and improve their living conditions.  In the years between 1976 and 1985 the understanding of immigrants however changed. During this period immigrants became increasingly problematized for their lack of employment and a cultural difference. During the end of this period the multicultural policy changed from an emphasis on culture as a resource for social inclusion to that some parts of of a Swedish identity were not subject of choice. Furthermore, this period also lead to increased efforts at the individual level, were the policy aimed to give individual immigrants increased chances at the labor market. During the last fifteen years the 20th century immigrant policy became increasingly politicized, and immigrants became understood as radically culturally different from swedes. In this period immigrant culture were constructed as oppressive towards women and outdated when compared to the modern Swedish culture. Furthermore, the notion of immigrants as unemployed from previous decades continued to play an important part and immigrants were also conceived as living segregated. This view resulted in the creation of integration policies aiming to not handle immigrants as a from the general population different group. Instead, immigrants should become integrated in Swedish society through the general welfare with an emphasis that not all parts of a Swedish identity were choose able.The result of the investigation show that European culture became increasingly normative in the development of Swedish migrant policy, thus excluding European immigrants from the problematized immigrant subject. Thereby the globalization of migration towards Sweden led to a development were immigrant policy shifted focus from class to cultural perspectives. 
  •  
15.
  •  
16.
  • Bergqvist, D, et al. (författare)
  • Extraanatomic vascular reconstruction in patients with aorto-iliac arteriosclerosis
  • 1984
  • Ingår i: Acta Chirurgica Scandinavica. - 0001-5482. ; 150:3, s. 205-209
  • Tidskriftsartikel (refereegranskat)abstract
    • During an 11-year period 117 extraanatomic reconstructions were made for aorto-iliac arteriosclerosis; 36 axillofemoral and 81 femorofemoral crossover bypasses. The patients were old and had several factors making them poor risks for surgery. Axillofemoral grafts were more often used in patients with malignant disease. Postoperative mortality was 10% without difference between the two types of reconstruction. Both early and late complications were significantly more frequent in patients with axillofemoral bypass. Reoperations for occlusion and symptoms from the donor side also were significantly more common among axillofemoral patients. Life table analysis showed a higher survival and patency rate among patients with crossover grafts.
  •  
17.
  • Berntsen, Peter, 1974, et al. (författare)
  • Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells
  • 2010
  • Ingår i: Journal of the Royal Society Interface. - : The Royal Society. - 1742-5689 .- 1742-5662. ; 7:Suppl 3
  • Tidskriftsartikel (refereegranskat)abstract
    • The past decade has seen significant increases in combustion-generated ambient particles, which contain a nanosized fraction (less than 100 nm), and even greater increases have occurred in engineered nanoparticles (NPs) propelled by the booming nanotechnology industry. Although inhalation of these particulates has become a public health concern, human health effects and mechanisms of action for NPs are not well understood. Focusing on the human airway smooth muscle cell, here we show that the cellular mechanical function is altered by particulate exposure in a manner that is dependent upon particle material, size and dose. We used Alamar Blue assay to measure cell viability and optical magnetic twisting cytometry to measure cell stiffness and agonist-induced contractility. The eight particle species fell into four categories, based on their respective effect on cell viability and on mechanical function. Cell viability was impaired and cell contractility was decreased by (i) zinc oxide (40-100 nm and less than 44 mu m) and copper(II) oxide (less than 50 nm); cell contractility was decreased by (ii) fluorescent polystyrene spheres (40 nm), increased by (iii) welding fumes and unchanged by (iv) diesel exhaust particles, titanium dioxide (25 nm) and copper(II) oxide (less than 5 mu m), although in none of these cases was cell viability impaired. Treatment with hydrogen peroxide up to 500 mu M did not alter viability or cell mechanics, suggesting that the particle effects are unlikely to be mediated by particle-generated reactive oxygen species. Our results highlight the susceptibility of cellular mechanical function to particulate exposures and suggest that direct exposure of the airway smooth muscle cells to particulates may initiate or aggravate respiratory diseases.
  •  
18.
  • Berntsen, Peter, 1974, et al. (författare)
  • The serial millisecond crystallography instrument at the Australian Synchrotron incorporating the "Lipidico" injector
  • 2019
  • Ingår i: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 90:8
  • Tidskriftsartikel (refereegranskat)abstract
    • A serial millisecond crystallography (SMX) facility has recently been implemented at the macromolecular crystallography beamline, MX2 at the Australian Synchrotron. The setup utilizes a combination of an EIGER X 16M detector system and an in-house developed high-viscosity injector, "Lipidico." Lipidico uses a syringe needle to extrude the microcrystal-containing viscous media and it is compatible with commercially available syringes. The combination of sample delivery via protein crystals suspended in a viscous mixture and a millisecond frame rate detector enables high-throughput serial crystallography at the Australian Synchrotron. A hit-finding algorithm, based on the principles of "robust-statistics," is employed to rapidly process the data. Here we present the first SMX experimental results with a detector frame rate of 100 Hz (10 ms exposures) and the Lipidico injector using a mixture of lysozyme microcrystals embedded in high vacuum silicon grease. Details of the experimental setup, sample injector, and data analysis pipeline are designed and developed as part of the Australian Synchrotron SMX instrument and are reviewed here. Published under license by AIP Publishing.
  •  
19.
  •  
20.
  •  
21.
  • Boman, Mattias, et al. (författare)
  • Outdoor recreation - A necessity or a luxury? : Estimation of Engel curves for Sweden
  • 2013
  • Ingår i: Journal of Outdoor Recreation and Tourism. - : Elsevier BV. - 2213-0780 .- 2213-0799. ; 3-4, s. 49-56
  • Tidskriftsartikel (refereegranskat)abstract
    • Income constitutes one important constraint for the degree of participation in outdoor recreation. The effect of this constraint can be measured by the income elasticity of outdoor recreation demand, which is of policy interest when the distribution of recreation opportunities across socioeconomic groups is a concern. This study investigated income elasticity of expenditures for three types of outdoor recreation in Sweden, at the individual level: outdoor recreation as an aggregated composite good, outdoor recreation close to home (less than 100 km away from the permanent residence), and hunting. The findings indicated that outdoor recreation as a composite is a luxury good with elasticity in excess of unity (i.e. a relative increase in income will lead to a greater relative increase in demand). The elasticities of the specific activities were found to be lower. Outdoor recreation close to home was characterized as a necessity with elasticity less than unity (i.e. a relative increase in income will lead to a smaller relative increase in demand). The results further suggested that an increase in income could lead to either a decrease or an increase in the demand for hunting, indicating that hunting might be an inferior good or possibly a necessity. Management implications Based on data from national surveys in Sweden, this paper explores the relationship between income and demand for different types of outdoor recreation activities. The analysis reveals that: The total demand for outdoor recreation opportunities can be expected to increase with increasing income levels in society. An increase in total demand does, however, not imply that demand for all types of outdoor recreation will increase simultaneously.The relationship between income and outdoor recreation demand differs among various types of recreation activities. Outdoor recreation close to home and hunting provided two examples of such diverging patterns in this paper. This, in turn, leads to different policy implications.Policy measures should, therefore, be adapted to the specific type of outdoor recreation under consideration.Managers need to be aware of the underlying factors affecting demand, such as socioeconomic characteristics, substitutability, motivations and different types of constraints.Future analysis should consider also the following factors potentially affecting outdoor recreation demand:- The distinction between recreation enjoyed during overnight trips (i.e. tourism related), as opposed to day based recreation activities where income may be less important.- The time available for outdoor recreation and the family situation.- Recreational activities must be regarded within the regulatory national framework. For example hunting in Sweden is guided by bag limits, reduced mobility because of limited access to specific hunting grounds, and specific national management of hunting opportunities. © 2013 Elsevier Ltd.
  •  
22.
  •  
23.
  •  
24.
  •  
25.
  • Cedervall, Johan, et al. (författare)
  • Influence of cobalt substitution on the magnetic properties of Fe5PB2
  • 2018
  • Ingår i: Inorganic Chemistry. - : American Chemical Society (ACS). - 0020-1669 .- 1520-510X. ; 57:2, s. 777-784
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study the effects of cobalt substitutions in Fe5PB2 have been studied. An increased cobalt content reduces the magnetic exchange interactions. This has been concluded from a large, linear decrease in both the Curie temperature as well as the saturated magnetic moment. At high cobalt concentrations, cobalt prefers to order at the M(2) position in the crystal structure. A tunable Curie transition like this shows some prerequisites for magnetic cooling applications.The substitutional effects of cobalt in (Fe1–xCox)5PB2 have been studied with respect to crystalline structure and chemical order with X-ray diffraction and Mössbauer spectroscopy. The magnetic properties have been determined from magnetic measurements, and density functional theory calculations have been performed for the magnetic properties of both the end compounds, as well as the chemically disordered intermediate compounds. The crystal structure of (Fe1–xCox)5PB2 is tetragonal (space group I4/mcm) with two different metal sites, with a preference for cobalt atoms in the M(2) position (4c) at higher cobalt contents. The substitution also affects the magnetic properties with a decrease of the Curie temperature (TC) with increasing cobalt content, from 622 to 152 K for Fe5PB2 and (Fe0.3Co0.7)5PB2, respectively. Thus, the Curie temperature is dependent on composition, and it is possible to tune TC to a temperature near room temperature, which is one prerequisite for magnetic cooling materials.
  •  
26.
  • Chachage, Chachage Seithy L., et al. (författare)
  • Mining and structural adjustment : studies on Zimbabwe and Tanzania
  • 1993
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • The mining sector has played an historically central role in the economy of Africa, but large-scale investment in it declined after 1970. Structural adjustment and the dismantling of apartheid opens up the possibility of a revival of such investment, but also raises questions about the terms on which it will take place and the fate of local small-scale mining industries. These two studies examine tensions between large- and small-scale mining in Tanzania, and the emergence of new forms of relation between international mining houses and the national state in Zimbabwe.
  •  
27.
  • Collsiöö, August, et al. (författare)
  • Do We Know What We Are Doing? A Multi-Method Mapping of Intuitive and Analytic Thought in Rule-Based and Memory-Based Processes
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • In this article, we compare two different ways of defining intuitive- and analytic thought processes. One is the standard fast-and-slow dual-process perspective, emphasizing that intuitive processes are autonomous and fast, whereas analytic processes are slow and deliberative. An older Brunswikian perspective emphasizes that intuition is approximate, drawing on processes of perception and memory, which yield Gaussian error distributions. Analytic processes instead involve deterministic use of rules and symbols that yield spikey leptokurtic error distributions. Across four experiments involving multiple-cue judgment, participants provided brief written retrospective reports on how they mentally performed the judgments (n = 284). Observers coded these reports as involving either intuitive or analytic cognitive processes and if they drew on cue abstraction or exemplar memory, according to a pre-defined coding scheme that did not refer to response times or error distributions. Data from the judgment phase of the experiments were then analyzed separately for participants categorized as drawing on “intuitive” or “analytic” cognitive processes. The key question was to what degree the predictions of the two perspectives are supported when participants are categorized as predominantly relying on an intuitive or analytic process based on their written description of their thought process. Bayesian hypothesis testing comparing participants coded as intuitive and analytic demonstrated that, at least in these tasks, there was strong evidence against the fast-and-slow dual-process prediction of higher response times for analytic participants, but strong evidence in favor of different error distributions in line with the Brunswikian hypothesis.
  •  
28.
  • Connor, Peter, et al. (författare)
  • Devising renewable heat policy: Overview of support options
  • 2013
  • Ingår i: Energy Policy. - : Elsevier BV. - 1873-6777 .- 0301-4215. ; 59, s. 3-16
  • Tidskriftsartikel (refereegranskat)abstract
    • Renewable energy sources of heat offer the substantial economic, environmental and social benefits associated with renewable electricity but policy to support their expansion is considerably less advanced. The potential for applying various support instruments to renewable heat is considered with advantages and disadvantages discussed. (c) 2012 Published by Elsevier Ltd.
  •  
29.
  • Ericsson, Andreas, et al. (författare)
  • A combined electromagnetic and acoustic analysis of a triaxial carbon fiber weave for reflector antenna applications
  • 2016
  • Ingår i: Aerospace Science and Technology. - : Elsevier. - 1270-9638 .- 1626-3219. ; 58, s. 401-417
  • Tidskriftsartikel (refereegranskat)abstract
    • Fiber composites are widely used for space applications such as antennas, solar panels and spacecraft support structures. This paper presents a combined electromagnetic and acoustic analysis of a triaxial carbon fiber weave structure, designed for ultra lightweight reflector antennas in satellite communication systems. The electromagnetic and acoustic performance of the structure are analyzed over a wide range of parametric studies, both at a microscopic and mesoscopic length scale. The electromagnetic study indicates that the main parameter governing the electromagnetic reflection performance of the weave is the electric conductivity of the carbon fibers, given that the weave structure is significantly smaller than the wavelength of the incident signals. The acoustic study identifies a critical threshold in the mesoscale geometry in order to avoid a critically high resistive behavior of the weave structure, driven by viscous effects. Design guidelines are drawn from these analyses in order to achieve a trade-off between the electromagnetic reflection properties and the resistance to acoustic loading of such composite materials. These combined analyses allow to deepen the understanding from both an electromagnetic and acoustic perspective in order to open for some new design possibilities.
  •  
30.
  • Ericsson, Emma, 1981-, et al. (författare)
  • Controlled Orientation and Covalent Attachment of Proteins on Biosensor Surfaces by Chelation Assisted Photoimmobilization
  • 2013
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • This report presents a novel method for uniform orientation and covalent attachment of proteins to sensing surfaces, termed Chelation Assisted Photoimmobilization (CAP). Alkanethiols terminated with either nitrilotriacetic acid (NTA), benzophenone (BP) or oligo(ethylene glycol) were synthesized and mixed self-assembled monolayers (SAMs) were prepared on gold and thoroughly characterized by infrared reflection absorption spectroscopy (IRAS), ellipsometry and contact angle goniometry. In the process of CAP, NTA chelates Ni2+ and the complex coordinates a His-tagged ligand in an oriented assembly. The ligand is then photoimmobilized via BP, which forms covalent bonds upon UV light activation. The CAP concept was demonstrated using human IgG-Fc modified with C-terminal hexahistidine tags (His-IgGFc) as the ligand and protein A as the analyte.In the development of affinity biosensors, uniform orientation of ligand molecules where all analyte binding sites are accessible is often preferred to random orientation. In order to monitor the effect of ligand orientation on analyte response, the ligand-analyte interaction was quantified by surface plasmon resonance analysis, both in the case of CAP and when the ligand was attached by conventional amine coupling on surfaces presenting NTA. Responses were adjusted for differences in ligand immobilization level using IRAS. The normalized analyte response with randomly oriented ligand was 2.5 times higher than that with ligand immobilized by CAP, probably due to molecular crowding effects on the surface and the fact that His-IgGFc is bivalent for protein A. This is a reminder that many other factors than orientation alone may play a decisive role in analyte binding on biosensor surfaces.
  •  
31.
  • Ericsson, Emma M, et al. (författare)
  • Controlled orientation and covalent attachment of proteins on biosensor surfaces by Chelation Assisted Photoimmobilization
  • 2013
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • In the context of surface chemistry for affinity biosensor chips, it is widely accepted that uniform orientation of the immobilized recognition element (ligand) is preferred over random orientation. However, this assumption has often been based on studies where differences in ligand immobilization level have not been taken into account. In this contribution, we present a novel two-step method for homogenous orientation and covalent attachment of proteins to sensing surfaces, called Chelation Assisted Photoimmobilization (CAP). Careful quantification of the effect of ligand orientation on analyte responses was performed by comparing this strategy to immobilization by conventional amine coupling. In CAP, the chelation agent is nitrilotriacetic acid (NTA) which chelates Ni2+. A His-tagged ligand forms an oriented assembly when binding Ni2+-NTA and is then covalently bound to the surface via photolabile benzophenone (BP), which attacks C-H bonds upon UV light activation. We relied on a surface chemistry based on self-assembled monolayers (SAMs) of oligo(ethylene glycol) (OEG)-containing alkanethiolates on gold. Alkanethiols terminated with either NTA, BP or OEG were synthesized and mixed SAMs were characterized by infrared reflection absorption spectroscopy (IRAS), ellipsometry and contact angle goniometry. IRAS was also used to quantify ligand immobilization levels obtained either by CAP or by amine coupling via the carboxyl groups of an NTA-presenting surface. The model ligand was human IgG-Fc modified with a C-terminal 6xHis-tag and the analyte was Protein A. The ligand-analyte interaction was quantified by a surface plasmon resonance biosensor. Analyte responses were normalized with respect to the ligand amounts obtained by the two immobilization strategies. Interestingly, the normalized analyte response with randomly oriented ligand was >2 times higher than that with ligand immobilized by CAP. This shows that oriented ligand immobilization is not necessarily a means of increasing the sensitivity of a biosensor. Factors that may influence performance include the valency of the ligand and constraints related to the surface chemistry used for orientation.
  •  
32.
  • Ericsson, Emma, et al. (författare)
  • Oriented Protein Immobilization by Chelate Associated Photochemistry
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • We demonstrate herein the synthesis, characterization and application of a novel chelateassociated photochemistry (CAP) for oriented and robust attachment of biomolecular ligandsto sensing surfaces. The chelation agent is nitrilotriacetic acid (NTA) which is capable ofcoordinating two histidine (His) molecules in the presence of Nickel. Therefore a ligandmodified with a His-sequence can be attached to NTA to form an oriented assembly ofligands on the sensor surface. The ligand is then covalently bound to the surface via a nearbyphotolabile benzophenone (BP) which attacks C-H bonds upon UV light activation. Theligand is then available for analyte interaction. The synthesized compounds used in this studyare based on the well-known organosulphur surface chemistry for proper attachment to goldsurfaces. Besides the two BP and NTA alkane thiols/disulphides we also synthesized a fillermolecule with an oligo (ethylene glycol) (OEG) tail to fine tune the surface composition andto reduce non-specific binding. Results from surface plasmon resonance (SPR) measurementsusing a Biacore 3000 instrument indicate that up to 55% larger analyte response is obtainedwith CAP as compared to the response obtained with the random orientation achieved byphotoimmobilization alone.
  •  
33.
  • Ericsson, Emma, et al. (författare)
  • Site-Specific and Covalent Attachment of His-Tagged Proteins by Chelation Assisted Photoimmobilization: A Strategy for Microarraying of Protein Ligands
  • 2013
  • Ingår i: Langmuir. - : American Chemical Society. - 0743-7463 .- 1520-5827. ; 29:37, s. 11687-11694
  • Tidskriftsartikel (refereegranskat)abstract
    • A novel strategy for site-specific and covalent attachment of proteins has been developed, intended for robust and controllable immobilization of histidine (His)-tagged ligands in protein microarrays. The method is termed chelation assisted photoimmobilization (CAP) and was demonstrated using human IgG-Fc modified with C-terminal hexahistidines (His-IgGFc) as the ligand and protein A as the analyte. Alkanethiols terminated with either nitrilotriacetic acid (NTA), benzophenone (BP); or oligo(ethylene glycol) were synthesized and mixed self-assembled monolayers (SAMs) were prepared on gold and thoroughly characterized by infrared reflection absorption spectroscopy (IRAS), ellipsometry, and contact angle goniometry. In the process of CAP, NTA chelates Ni2+ and the complex coordinates the His-tagged ligand in an oriented assembly. The ligand is then photoimmobilized via BP, which forms covalent bonds upon UV light activation. In the development of affinity biosensors and protein microarrays, site-specific attachment of ligands in a fashion where analyte binding sites are available is often preferred to random coupling. Analyte binding performance of ligands immobilized either by CAP or by standard amine coupling was characterized by surface plasmon resonance in combination with IRAS. The relative analyte response with randomly coupled ligand was 2.5 times higher than when site-specific attachment was used. This is a reminder that also when immobilizing ligands via residues far from the binding site, there are many other factors influencing availability and activity. Still, CAP provides a valuable expansion of protein immobilization techniques since it offers attractive microarraying possibilities amenable to applications within proteomics.
  •  
34.
  • Ericsson, Hans, et al. (författare)
  • The glucokinase activator AZD6370 decreases fasting and postprandial glucose in type 2 diabetes mellitus patients with effects influenced by dosing regimen and food
  • 2012
  • Ingår i: Diabetes Research and Clinical Practice. - : Elsevier. - 0168-8227 .- 1872-8227. ; 98:3, s. 436-444
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: To investigate the pharmacodynamics, pharmacokinetics and safety of the glucokinase activator AZD6370 after 1 day of administration under fed and fasted conditions in patients with type 2 diabetes mellitus (T2DM). less thanbrgreater than less thanbrgreater thanMethods: This was a two-part study. In Part A, patients received a single oral dose of AZD6370 (20, 60 or 180 mg) or placebo in the fasted or fed states (both n = 8). In Part B, patients (n = 8) received placebo and a total dose of AZD6370 180 mg given in one, two or four divided doses. Plasma glucose, insulin and C-peptide changes versus placebo were assessed. less thanbrgreater than less thanbrgreater thanResults: AZD6370 provided dose-dependent reductions in plasma glucose of up to 30% versus placebo in both fasted and fed patients (p andlt; 0.001 at 60 and 180 mg doses). Insulin secretion increased with dose, but absolute increases were relatively small in the fasted versus fed state (0-4 h). Dosing AZD6370 twice or four-times over 1 day gave a smoother 24-h glucose profile than single-dose. AZD6370 was rapidly absorbed. Pharmacokinetics of AZD6370 were dose-independent and unaffected by food. AZD6370 was generally well tolerated. less thanbrgreater than less thanbrgreater thanConclusions: AZD6370 produced dose-dependent glucose reductions and increased glucose-stimulated insulin secretion in patients with T2DM.
  •  
35.
  •  
36.
  •  
37.
  • Ericsson, Olle, et al. (författare)
  • Clinical validation of a novel automated cell-free DNA screening assay for trisomies 21, 13, and 18 in maternal plasma.
  • 2019
  • Ingår i: Prenatal diagnosis. - : Wiley. - 1097-0223 .- 0197-3851. ; 39:11, s. 1011-1015
  • Tidskriftsartikel (refereegranskat)abstract
    • To evaluate clinical performance of a new automated cell-free (cf)DNA assay in maternal plasma screening for trisomies 21, 18, and 13, and to determine fetal sex.Maternal plasma samples from 1200 singleton pregnancies were analyzed with a new non-sequencing cfDNA method, which is based on imaging and counting specific chromosome targets. Reference outcomes were determined by either cytogenetic testing, of amniotic fluid or chorionic villi, or clinical examination of neonates.The samples examined included 158 fetal aneuploidies. Sensitivity was 100% (112/112) for trisomy 21, 89% (32/36) for trisomy 18, and 100% (10/10) for trisomy 13. The respective specificities were 100%, 99.5%, and 99.9%. There were five first pass failures (0.4%), all in unaffected pregnancies. Sex classification was performed on 979 of the samples and 99.6% (975/979) provided a concordant result.The new automated cfDNA assay has high sensitivity and specificity for trisomies 21, 18, and 13 and accurate classification of fetal sex, while maintaining a low failure rate. The study demonstrated that cfDNA testing can be simplified and automated to reduce cost and thereby enabling wider population-based screening.
  •  
38.
  •  
39.
  • Ericsson, Peter, 1963- (författare)
  • Att använda case-metoden i grundutbildningen i Historia : Projektrapport
  • 2008
  • Rapport (populärvet., debatt m.m.)abstract
    • Implementing the case-method into undergraduate educa­tion in History The purpose of the project is to introduce the case-method into under­graduate education in History. This has been achieved by constructing a number of cases, i.e. short narratives, on central historical issues. These issues have then been discussed at case-seminars. The benefits of this method are that our teaching can be related to current research; that we can make the study of history tangible without omitting a theoretical perspective; that the students are encouraged to independent, critical analysis; and, not least, that student motivation seems to improve. The cases produced within the project will be published as a text­book.
  •  
40.
  •  
41.
  • Ericsson, Peter (författare)
  • Corporative Privileges Undermined. : The Meaning of Extra-Ordinary Taxation in Sweden in the 17th and 18th Centuries
  • 2008
  • Ingår i: La Fiscalità nell'economia europea. Secc. XIII-XVIII • Fiscal Systems in the European Economy 13th - 18th Centuries.. - 9788884537034
  • Konferensbidrag (refereegranskat)abstract
    • The point of departure for this paper is the notion that taxation in Sweden in the 17th and 18th centuries was a special case. It was essentially direct, periodic and individual in character. Based on that, the communicative aspects of extra-ordinary taxation are considered. To do something to someone is to make a statement. The solutions to the questions of who should pay, and how much different groups and individuals should pay, can be seen as an articulation of the relationship between different groups or classes. The social distribution of taxation thus had ideological implications.In the course of the 17th century extra-ordinary taxation in Sweden was not only levied on individual peasant households, but it was also targeting specific crafts and professions, particularly civil servants and military officers. In the 18th century this became even more evident, although it was never an unproblematic or uninterrupted process.Thus, extra-ordinary taxation in Sweden tended to undermine corporative privileges, in particular noble privileges. It adhered to the principle that the rich should make a more substan¬tial contribution to the common good than those who had less. In this way, it conveyed a type of christian morality at the same time as it expressed a political program. This process can in turn be related to the pro¬cess in which royal subjects were transformed into citizens.
  •  
42.
  •  
43.
  •  
44.
  • Ericsson, Peter, et al. (författare)
  • Gastrin release: Antrum microdialysis reveals a complex neural control.
  • 2010
  • Ingår i: Regulatory Peptides. - : Elsevier BV. - 1873-1686 .- 0167-0115. ; 161, s. 22-32
  • Tidskriftsartikel (refereegranskat)abstract
    • We used microdialysis to monitor local gastrin release in response to food, acid blockade and acute vagal excitation. For the first time, gastrin release has been monitored continuously in intact conscious rats in a physiologically relevant experimental setting in a fashion that minimizes confounding systemic effects. Microdialysis probes were placed in the submucosa on either side of the antrum, 3days before the experiments. The concentration of gastrin in the antral submucosal compartment was 5-10 times higher than in serum regardless of the prandial state. The rats were conscious during microdialysis except when subjected to electrical vagal stimulation. Acid blockade (omeprazole treatment of freely fed rats for 4days), or bilateral sectioning of the abdominal vagal trunks (fasted rats), raised the gastrin concentration in blood as well as microdialysate. The high gastrin concentration following omeprazole treatment was not affected by vagotomy. Vagal excitation stimulated the G cells: electrical vagal stimulation and pylorus ligation (fasted rats) raised the gastrin concentration transiently in both serum and microdialysate. Food intake induced a 2- to 3-fold increase in serum gastrin, while gastrin in antral microdialysate increased 10- to 15-fold. In unilaterally vagotomized rats, food evoked a prompt peak gastrin release followed by a gradual decline on the intact side. On the vagotomized side of the antrum, the peak response seemed to be reduced while the microdialysate gastrin concentration remained elevated. Thus, unilateral vagotomy surprisingly raised the integrated gastrin response to food on the denervated side compared to the intact side, indicating that vagotomy suppresses an inhibitory as well as a stimulating effect on the G cells. While local infusion of atropine was without effect, infusion of the neuronal blocker tetrodotoxin (TTX) (which had no effect on basal gastrin) virtually abolished the food-evoked gastrin response and lowered the high microdialysate gastrin concentration in omeprazole-treated rats by 65%. We conclude that activated gastrin release, unlike basal gastrin release, is highly dependent on a neural input: 1) Vagal excitation has a transient stimulating effect on the G cells. The transient nature of the response suggests that the vagus has not only a prompt stimulatory but also a slow inhibitory effect on gastrin release. 2) Although vagal denervation did not affect the gastrin response to anacidity, the TTX experiments revealed that both food-evoked and anacidity-evoked gastrin release depends on neural input.
  •  
45.
  • Ericsson, Peter, et al. (författare)
  • Gastrin response to candidate messengers in intact conscious rats monitored by antrum microdialysis.
  • 2010
  • Ingår i: Regulatory Peptides. - : Elsevier BV. - 1873-1686 .- 0167-0115. ; 163, s. 24-30
  • Tidskriftsartikel (refereegranskat)abstract
    • We monitored gastrin release in response to locally applied candidate messengers in intact conscious rats. Earlier studies have been performed on anaesthetized animals, isolated pieces of antrum, or purified preparations of gastrin cells. In this study we created an experimental situation to resemble physiological conditions, using reverse microdialysis to administer regulatory peptides and amines that might affect gastrin secretion. Microdialysis probes were implanted in the submucosa of the antrum of the rat stomach. Three days later, putative messenger compounds were administered via the probe. Their effects on basal (24h fast) and omeprazole-stimulated (400mumol/kg/day, 4days peroral administration) gastrin release were monitored by continuous measurement (3h) of gastrin in the perfusate (radioimmunoassay). Fasted rats (low microdialysate gastrin, 2.1+/-0.1pmoll(-1)) were used to study stimulation of gastrin release. Omeprazole-treated rats (high microdialysate gastrin, 95.8+/-6.7pmoll(-1)) were used to study suppression of gastrin release. The following agents raised the concentration of microdialysate gastrin (peak response): gastrin-releasing peptide (GRP) (11-fold increase at a near-maximal dose), carbachol (5-fold increase), serotonin (2-fold increase) and isoprenaline (20-fold increase). Adrenaline and noradrenaline induced transient but powerful elevation (40- and 20-fold increase). Somatostatin, galanin and bradykinin (at near-maximal doses) suppressed omeprazole-stimulated gastrin release (50% decrease). Calcitonin gene-related peptide, ghrelin, gastric inhibitory peptide, motilin, neurotensin, neuromedin U-25, peptide YY and vasoactive intestinal peptide were without effect on gastrin release, as were aspartate, gamma-aminobutyric acid, glutamate, glycine, dopamine and histamine. The results support the view that G cells operate under neurocrine/paracrine control. They were stimulated by agents present in enteric neurons (GRP, galanin, choline ester and catechol amines) and in gastric endocrine cells (serotonin). They were inhibited by somatostatin (D cell peptide), galanin (neuropeptide) and by the inflammatory agent bradykinin.
  •  
46.
  • Ericsson, Peter (författare)
  • Inledning
  • 2007
  • Ingår i: Gud, konung och undersåtar. - Uppsala : Historiska institutionen, Uppsala universitet. - 9789197731201 ; , s. 5-9
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
  •  
47.
  •  
48.
  •  
49.
  •  
50.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-50 av 117
Typ av publikation
tidskriftsartikel (59)
konferensbidrag (16)
bokkapitel (16)
rapport (7)
annan publikation (7)
doktorsavhandling (5)
visa fler...
samlingsverk (redaktörskap) (3)
recension (3)
licentiatavhandling (1)
visa färre...
Typ av innehåll
refereegranskat (62)
övrigt vetenskapligt/konstnärligt (50)
populärvet., debatt m.m. (5)
Författare/redaktör
Ericsson, Peter, 196 ... (20)
Ericsson, Tore (6)
Häggström, Lennart (6)
Ericsson, Magnus (6)
Ericsson, Stina, 197 ... (6)
Nilsson, Peter (5)
visa fler...
Svedlindh, Peter (5)
Håkanson, Rolf (5)
Ljunglöf, Peter, 197 ... (5)
Norlén, Per (5)
Ericsson, Göran (4)
Liedberg, Bo (4)
Enander, Karin (4)
Konradsson, Peter (4)
Larsson, Staffan, 19 ... (4)
Auffray, C (3)
De Meulder, B (3)
Wheelock, CE (3)
Dahlen, SE (3)
Djukanovic, R (3)
Sterk, PJ (3)
Chung, KF (3)
Montuschi, P (3)
Fowler, SJ (3)
Sandström, Thomas, 1 ... (3)
Shaw, DE (3)
Bates, S (3)
Lundström, Ingemar (3)
Kolmert, J (3)
Ostling, J (3)
Dahlen, Sven-Erik (3)
Gomez, C (3)
Ericsson, M (3)
Thorngren, JO (3)
Bakke, PS (3)
Caruso, M (3)
Horvath, I (3)
Krug, N (3)
Alving, Kjell, 1959- (3)
Kolmert, Johan (3)
Jonson, Rebecca, 197 ... (3)
Milward, David (3)
Ericsson, Thomas, 19 ... (3)
Cedervall, Johan (3)
Sahlberg, Martin, 19 ... (3)
Kupczyk, M. (3)
James, Anna (3)
Dahlén, Barbro (3)
Mikus, Maria (3)
Bui, Lan (3)
visa färre...
Lärosäte
Uppsala universitet (48)
Lunds universitet (22)
Göteborgs universitet (16)
Kungliga Tekniska Högskolan (11)
Karolinska Institutet (11)
Umeå universitet (9)
visa fler...
Örebro universitet (8)
Linköpings universitet (5)
Chalmers tekniska högskola (5)
Stockholms universitet (3)
RISE (3)
Sveriges Lantbruksuniversitet (3)
Luleå tekniska universitet (2)
Malmö universitet (2)
Mittuniversitetet (2)
Högskolan i Borås (2)
Nordiska Afrikainstitutet (1)
Högskolan i Gävle (1)
Högskolan Väst (1)
Mälardalens universitet (1)
Södertörns högskola (1)
Linnéuniversitetet (1)
Karlstads universitet (1)
Försvarshögskolan (1)
visa färre...
Språk
Engelska (90)
Svenska (24)
Franska (2)
Ryska (1)
Forskningsämne (UKÄ/SCB)
Humaniora (34)
Medicin och hälsovetenskap (32)
Naturvetenskap (20)
Samhällsvetenskap (16)
Teknik (7)
Lantbruksvetenskap (3)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy