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1.
  • Eriksson, Christina, et al. (författare)
  • Occupational therapists' perceptions of implementing a client-centered intervention in close collaboration with researchers : A mixed methods study
  • 2020
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 27:2, s. 142-153
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Integration of research-based knowledge in health care is challenging. Occupational therapists (OTs) need to implement new research-based interventions in clinical practice. Therefore it is crucial to recognize and understand the factors of specific barriers and facilitators affecting the implementation process. Aim: To identify the key factors important for OTs during the implementation process of a complex intervention.Materials and methods: A cross-sectional study with a combination of qualitative and quantitative data in a mixed method design. Forty-one OTs and 23 managers from three county councils in Sweden, responded to a questionnaire one year after the OTs participation in a workshop to prepare for implementation of a client-centered activity of daily living intervention for persons with stroke.Results: Over 70% of the OTs benefitted from reading and discussing articles in the workshop; 60% had faith in the intervention; 69% reported usability of the intervention. High level of support from managers was reported, but less from team members. The therapists' interaction, perceptions of own efforts and contextual influence affected the implementation process.Conclusion: The workshop context with facilitation and access to evidence, supportive organizations and teams, sufficient interaction with researchers and satisfying self-image were successful key factors when involved in research.
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  • Eriksson, Therese, et al. (författare)
  • A comparison of perceived occupational gaps between people with stress-related ill health or musculoskeletal pain and a reference group
  • 2012
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 19:5, s. 411-420
  • Tidskriftsartikel (refereegranskat)abstract
    • Aim: To describe and compare how occupational gaps were reported in everyday occupations in a rehabilitation group of people with musculoskeletal pain or stress-related ill health and in a reference group from the Swedish population.Method: Seventy-two persons with musculoskeletal pain or stress-related ill health and 261 people from the Swedish population were included. The Occupational Gaps Questionnaire, measuring to what extent individuals perceive a discrepancy between what they want to do and what they actually do, was completed by the participants. Descriptive statistics were used to analyse the data.Results: Occupational gaps were reported more often in the rehabilitation group. Leisure activities were the gaps reported most often. The occupational repertoire seemed to decrease over time as the number of activities was decreasing, particularly leisure and work-related activities. Instrumental ADL were more desirable as the length of sick leave extended.Conclusions: Being on sick leave appears to start a process towards occupational deprivation where the areas that remain in the occupational repertoire become more important. Our study highlights the need to emphasize the whole occupational repertoire in rehabilitation and to facilitate engagement in valued activities to create a sound base for the process of returning to work.
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7.
  • Löfstedt, Tommy, et al. (författare)
  • Bi-modal OnPLS
  • 2012
  • Ingår i: Journal of Chemometrics. - : John Wiley & Sons. - 0886-9383 .- 1099-128X. ; 26:6, s. 236-245
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper presents an extension to the recently published OnPLS data analysis method. Bi-modal OnPLS allows for arbitrary block relationships in both columns and rows and is able to extract orthogonal variation in both columns and rows without bias towards any particular direction or matrix: the method is fully symmetric with regard to both rows and columns. Bi-modal OnPLS extracts a minimal number of globally predictive score vectors that exhibit maximal covariance and correlation in the column space and a corresponding set of predictive loading vectors that exhibit maximal correlation in the row space. The method also extracts orthogonal variation (i.e. variation that is not related to all other matrices) in both columns and rows. The method was applied to two synthetic datasets and one real data set regarding sensory information and consumer likings of dairy products. It was shown that Bi-modal OnPLS greatly improves the intercorrelations between both loadings and scores while still finding the correct variation. This facilitates interpretation of the predictive components and makes it possible to study the orthogonal variation in the data.
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8.
  • Adde, Magdalena, et al. (författare)
  • Superior outcome in transformed follicular lymphoma compared to de novo aggressive B-cell lymphoma treated with high-dose therapy and autologous stem-cell support
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Purpose: To assess the outcome of high–dose therapy with autologous stem cell support (HDT) in patients with transformed follicular lymphoma compared to patients with de novo aggressive B-cell lymphoma, in a retrospective analysis of patients treated at two Swedish university hospitals. Patients and Methods: 117 patients, mean age 48 years (21-65), 79 with de novo aggressive B-cell lymphoma and 38 with transformed follicular lymphoma, were treated with high-dose-therapy (HDT) as consolidation. Thirteen patients with transformed follicular lymphoma had been treated with a single alkylating agent and 25 were chemonaive at transformation. After transformation, nine patients had HDT as part of first line aggressive therapy, and a further eight failed to obtain CR and had HDT upfront. Twenty-one patients received more than one treatment regimen before HDT. In the de novo aggressive lymphoma group five patients with high risk criteria, and 16 patients who failed to obtain CR, received HDT upfront (CR1), Fifty-eight patients received more than one regimen before HDT because of relapse. Rituximab was given as a single dose to five patients for in vivo purging of the stem cell graft. Results: With a median follow up of 11.5 years (8-20), event free survival (EFS) and overall survival (OS) were 35% and 44% respectively. When comparing the two groups, the ten- year EFS rates were 27% in the de novo group and 55% in the transformed group and the ten-year OS was 33 % and 67% respectively. Treatment related mortality was acceptable with 4% early and 3.5% late mortality. In a multivariate analysis, “transformed vs de novo aggressive” histopathology was the only factor significantly related to outcome. Conclusion: Both EFS and OS were much better in patients with transformed follicular lymphoma compared to patients with de novo aggressive B-cell lymphoma Although the introduction of rituximab certainly has improved the outcome in both groups, HDT should still be considered as a salvage strategy not only in cases of de novo aggressive B-cell lymphoma and especially in transformed follicular lymphoma relapsing after first line treatment..
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9.
  • Agrell, Wilhelm, et al. (författare)
  • Sweden: A Delicate Liaison
  • 2016
  • Ingår i: The Handbook of European Intelligence Cultures. - 9781442249417 ; , s. 371-382
  • Bokkapitel (refereegranskat)
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10.
  • Ahlström, Christer, et al. (författare)
  • Validating speed and road surface realism in VTI driving simulator III
  • 2012
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Nya simulatormodeller för vibrationer, ljud och grafik har utvecklats och implementerats i VTI:S fordonssimulator III. Syftet med denna studie är att validera simulatorn med avseende på hastighet och återgivandet av olika vägyteparametrar. Tjugofyra försökspersoner deltog i studien. De fick köra en och samma rutt i såväl simulator III som på verklig väg. Tre vägavsnitt med olika kvalitet på vägytan, från mycket slät till ganska ojämn, ingick i försöket. Såväl den objektiva förarparametern hastighet som olika subjektiva parametrar avseende förarens uppfattning om vägytans egenskaper (jämnhet, tysthet, komfort) jämfördes. Ett vägavsnitt med skiftande hastighetsgränser var av speciellt intresse. Ingen signifikant skillnad kunde noteras mellan körning i simulator och på verklig väg vare sig avseende hastighet (på avsitt med konstant hastighetsgräns) eller gradering av jämnhet och tysthet. För sträckan med skiftande hastighetsgränser fanns dock en signifikant skillnad mellan hastigheten i bil jämfört med hastigheten i simulator, trots liknande hastighetsprofiler. Såväl accelerationerna som retardationerna var snabbare i simulatorn. Vägkomforten graderades högre i bil än i simulator, men i båda fallen var tendensen den att slätare vägar gav högre värdering av komforten. Dessa resultat indikerar absolut validitet för graderingen av jämnhet och tysthet och för det objektiva måttet hastighet, medan relativ validitet indikerades för såväl hastighet vid skylt för hastighetsändring som för gradering av komfort.
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11.
  • Amini, Rose-Marie, et al. (författare)
  • Altered profile of immune regulatory cells in the peripheral blood of lymphoma patients
  • 2019
  • Ingår i: BMC Cancer. - : BMC. - 1471-2407. ; 19
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Regulatory immune cells may modulate the lymphoma microenvironment and are of great interest due to the increasing prevalence of treatment with immunotherapies in lymphoma patients. The aim was to explore the composition of different immune regulatory cell subsets in the peripheral blood of newly diagnosed lymphoma patients in relation to treatment outcome. Methods: Forty-three newly diagnosed patients with lymphoma were included in the study; 24 with high-grade B-cell lymphoma (HGBCL) and 19 with classical Hodgkin lymphoma (cHL). Peripheral blood was prospectively collected and immune regulatory cells were identified by multi-color flow cytometry and analyzed in relation to healthy blood donors and clinical characteristics and outcome. Results: The percentage of CD3-positive T-cells was lower (p=0.03) in the peripheral blood of lymphoma patients at diagnosis compared to healthy blood donors regardless of lymphoma subtype, although statistically, neither the percentage of monocytes (p=0.2) nor the T-cell/monocyte ratio (p=0.055) differed significantly. A significant decrease in the percentage of a subset of regulatory NK cells (CD7(+)/CD3(-)/CD56(bright)/CD16(dim/-)) was identified in the peripheral blood of lymphoma patients compared to healthy blood donors (p=0.003). Lymphoma patients also had more granulocytic myeloid-derived suppressor cells (MDSCs) (p=0.003) compared to healthy blood donors, whereas monocytic MDSCs did not differ significantly (p=0.07). A superior disease-free survival was observed for cHL patients who had an increase in the percentage of granulocytic MDSCs (p=0.04). Conclusions: An altered profile of immune cells in the peripheral blood with a decrease in T-cells and regulatory NK-cells was observed in newly diagnosed lymphoma patients. CHL patients with higher percentages of regulatory NK cells and higher percentages of granulocytic MDSCs might have a better outcome, although the number of patients was low.
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12.
  • Anderson, Emma S., 1975-, et al. (författare)
  • Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro
  • 2000
  • Ingår i: Neuroscience Letters. - 0304-3940 .- 1872-7972. ; 284:1-2, s. 21-24
  • Tidskriftsartikel (refereegranskat)abstract
    • Accumulating data suggest that the oligodendrocyte population includes morphological and biochemical subtypes. We recently reported that a polyclonal antiserum against an unknown antigen, the T4-O molecule, labels a subpopulation of chicken oligodendrocytes, obviously representing the type IV variety of Del Rio Hortega. The present study examines the developmental expression of the T4-O molecule in situ and in vitro. The results show that T4-O immunoreactive cells first appear at E15 in the ventral funiculus. But, oligodendrocytes cultured in vitro with or without neurones do not develop a T4-O immunoreactivity. We conclude that oligodendrocytes in the spinal cord of chicken embryos first express the T4-O molecule some time after onset of myelination, and that the T4-O immunoreactive phenotype does not develop in vitro.
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  • Andersson, Cecilia K, et al. (författare)
  • Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis
  • 2011
  • Ingår i: Respiratory Research. - : Springer Science and Business Media LLC. - 1465-9921 .- 1465-993X. ; 12:139
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Although mast cells are regarded as important regulators of inflammation and tissue remodelling, their role in cystic fibrosis (CF) and idiopathic pulmonary fibrosis (IPF) has remained less studied. This study investigates the densities and phenotypes of mast cell populations in multiple lung compartments from patients with CF, IPF and never smoking controls. Methods: Small airways, pulmonary vessels, and lung parenchyma were subjected to detailed immunohistochemical analyses using lungs from patients with CF (20 lung regions; 5 patients), IPF (21 regions; 7 patients) and controls (16 regions; 8 subjects). In each compartment the densities and distribution of MCT and MCTC mast cell populations were studied as well as the mast cell expression of IL-6 and TGF-beta. Results: In the alveolar parenchyma in lungs from patients with CF, MCTC numbers increased in areas showing cellular inflammation or fibrosis compared to controls. Apart from an altered balance between MCTC and MCT cells, mast cell in CF lungs showed elevated expression of IL-6. In CF, a decrease in total mast cell numbers was observed in small airways and pulmonary vessels. In patients with IPF, a significantly elevated MCTC density was present in fibrotic areas of the alveolar parenchyma with increased mast cell expression of TGF-beta. The total mast cell density was unchanged in small airways and decreased in pulmonary vessels in IPF. Both the density, as well as the percentage, of MCTC correlated positively with the degree of fibrosis. The increased density of MCTC, as well as MCTC expression of TGF-beta, correlated negatively with patient lung function. Conclusions: The present study reveals that altered mast cell populations, with increased numbers of MCTC in diseased alveolar parenchyma, represents a significant component of the histopathology in CF and IPF. The mast cell alterations correlated to the degree of tissue remodelling and to lung function parameters. Further investigations of mast cells in these diseases may open for new therapeutic strategies.
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  • Andersson Sjöland, Annika, et al. (författare)
  • Fibroblast phenotypes and their activity are changed in the wound healing process after lung transplantation.
  • 2011
  • Ingår i: The Journal of Heart and Lung Transplantation. - : Elsevier BV. - 1557-3117 .- 1053-2498. ; 30, s. 945-954
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Lung transplantation (LTx) is established as a life-saving treatment in end-stage lung disease. However, long-term survival is hampered by the development of chronic rejection, almost synonymous with bronchiolitis obliterans syndrome (BOS). The rejection is characterized by deposition of extracellular matrix in small airways. Fibroblasts/myofibroblasts are the main producers of extracellular matrix molecules such as proteoglycans. This study compared fibroblast phenotype and activity in the wound healing process at different points after LTx in patients who later did, or did not, develop BOS. METHODS: Distally derived fibroblasts from patients 6 and 12 months after LTx and from healthy controls were analyzed for production of the proteoglycans versican, perlecan, biglycan, and decorin, with and without transforming growth factor (TGF)-β(1). Fibroblast migration and proliferation were also studied. RESULTS: At 6 and 12 months after LTx, versican production was higher in fibroblasts from LTx patients (p < 0.01 p < 0.01) than from controls. Fibroblasts from patients who later developed BOS were more responsive to TGF-β(1)-induced synthesis of versican and biglycan than patients without signs of rejection (p < 0.05). Production of perlecan and decorin was negatively correlated with fibroblast proliferation in fibroblasts at 6 months after LTx. In a more detailed case study of 2 patients, one with and one without BOS, the altered proteoglycan profile was associated with impaired lung function. CONCLUSIONS: LTx changes the phenotype of fibroblasts to a non-proliferative but extracellular matrix-producing cell due to wound healing involving TGF-β(1). If not controlled, this may lead to development of BOS.
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  • Andersson Sjöland, Annika, et al. (författare)
  • Fibrocytes and the tissue niche in lung repair
  • 2011
  • Ingår i: Respiratory Research. - : Springer Science and Business Media LLC. - 1465-9921 .- 1465-993X. ; 12
  • Forskningsöversikt (refereegranskat)abstract
    • Human fibrocytes are bone marrow-derived mesenchymal progenitor cells that express a variety of markers related to leukocytes, hematopoietic stem cells and a diverse set of fibroblast phenotypes. Fibrocytes can be recruited from the circulation to the tissue where they further can differentiate and proliferate into various mesenchymal cell types depending on the tissue niche. This local tissue niche is important because it modulates the fibrocytes and coordinates their role in tissue behaviour and repair. However, plasticity of a niche may be co-opted in chronic airway diseases such as asthma, idiopathic pulmonary fibrosis and obliterative bronchiolitis. This review will therefore focus on a possible role of fibrocytes in pathological tissue repair processes in those diseases.
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  • Andersson Sjöland, Annika, et al. (författare)
  • Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis.
  • 2009
  • Ingår i: Respiratory Research. - : Springer Science and Business Media LLC. - 1465-9921 .- 1465-993X. ; 10:Oct 30
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The aim of the present study was to explore the occurrence of fibrocytes in tissue and to investigate whether the appearance of fibrocytes may be linked to structural changes of the parenchyme and vasculature in the lungs of patients with obliterative bronchiolitis (OB) following lung or bone marrow transplantation. METHODS: Identification of parenchyme, vasculature, and fibrocytes was done by histological methods in lung tissue from bone marrow or lung-transplanted patients with obliterative bronchiolitis, and from controls. RESULTS: The transplanted patients had significantly higher amounts of tissue in the alveolar parenchyme (46.5 +/- 17.6%) than the controls (21.7 +/- 7.6%) (p < 0.05). The patients also had significantly increased numbers of fibrocytes identified by CXCR4/prolyl4-hydroxylase, CD45R0/prolyl4-hydroxylase, and CD34/prolyl4-hydroxylase compared to the controls (p < 0.01). There was a correlation between the number of fibrocytes and the area of alveolar parenchyma; CXCR4/prolyl 4-hydroxylase (p < 0.01), CD45R0/prolyl 4-hydroxylase (p < 0.05) and CD34/prolyl 4-hydroxylase (p < 0.05). In the pulmonary vessels, there was an increase in the endothelial layer in patients (0.31 +/- 0.13%) relative to the controls (0.037 +/- 0.02%) (p < 0.01). There was a significant correlation between the number of fibrocytes and the total area of the endothelial layer CXCR4/prolyl 4-hydroxylase (p < 0.001), CD45R0/prolyl 4-hydroxylase (p < 0.001) and CD34/prolyl 4-hydroxylase (p < 0.01). The percent areas of the lumen of the vessels were significant (p < 0.001) enlarged in the patient with OB compared to the controls. There was also a correlation between total area of the lumen and number of fibrocytes, CXCR4/prolyl 4-hydroxylase (p < 0.01), CD45R0/prolyl 4-hydroxylase (p < 0.001) and CD34/prolyl 4-hydroxylase (p < 0.01). CONCLUSION: Our results indicate that fibrocytes are associated with pathological remodelling processes in patients with OB and that tissue fibrocytes might be a useful biomarker in these processes.
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17.
  • Anåker, Anna, et al. (författare)
  • The physical environment and multi-professional teamwork in three newly built stroke units
  • 2020
  • Ingår i: Disability and Rehabilitation. - : Informa UK Limited. - 1464-5165 .- 0963-8288. ; , s. 1-9
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To explore multi-professional teamwork in relation to the physical environment in three newly built or renovated stroke units. Materials and methods: An observational study was undertaken. The participants were all staff members of a multi-professional team working in the reviewed stroke units. The data were collected using behavioural mapping and semi-structured observations, and they were analysed by content analysis and descriptive statistics. Results: Out of all the observations in the behavioural mapping, very few were of two or more members from the team together with a patient. None of the included stroke units had a co-location for all the members of the multi-professional team. Three main categories emerged from the analysis of the interviews: (i) the hub of the unit; (ii) the division of places; and (iii) power imbalance. All the categories reflected the teamwork in relation to parts of the physical environment. Conclusion: The design of the physical environment is important for multi-professional teamwork. Emphasis must be placed on better understanding the impact of the physical environment and on incorporating the evidence related to multi-professional teamwork during the design of stroke units.IMPLICATIONS FOR REHABILITATION Understanding the link between the physical environment and effective teamwork can lead to more tailored and supportive design solutions. The design of the physical environment should be considered as a vital part of effective teamwork in stroke units. The physical environment should include shared workstations, allowing team members to meet and communicate face to face.
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  • Backåberg, Sofia, 1979-, et al. (författare)
  • Sustainable human movements - a threshold concept with potential to open up new perspectives in physiotherapy
  • 2024
  • Ingår i: European Journal of Physiotherapy. - : Taylor & Francis Group. - 2167-9169 .- 2167-9177.
  • Tidskriftsartikel (refereegranskat)abstract
    • There is a call to action for physiotherapists worldwide to contribute to the transition towards 'sustainable health'. In this paper, we build upon the current definition of 'sustainable health' and also on 'sustainable physical activity' to introduce and theoretically substantiate the concept of sustainable human movements, and suggest a definition thereof. Sustainable human movements will be described as a threshold concept with three aligned critical concepts; (i) movement control, including forces as causes of emerging movements, (ii) movement quality, referring to how movements are performed in terms of optimisation, and (iii) physical literacy, including motivation, confidence and physical competence. A deep understanding of these concepts, combined with a collaboration and learning approach applied together with the patient, is proposed to enable a sustainable human movement approach to permeate physiotherapy theory and practice. To facilitate this, a generic and easily accessible tool has recently been developed. It combines support for structured observational movement analysis and pedagogical support for creating a mutual and extended understanding of a patient's lived experience. This encourages the patient to become actively involved and take responsibility for promoting his/her 'sustainable health'. The aims of this paper are to a) suggest a theoretical framework for and definition of the concept sustainable human movements, and b) introduce a clinical tool that ultimately aims at promoting sustainable movements and health.
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20.
  • Balldin, Ulf, et al. (författare)
  • Color vision with rapid-onset acceleration
  • 2003
  • Ingår i: Aviation, Space and Environmental Medicine. - 0095-6562 .- 1943-4448. ; 74:1, s. 29-36
  • Tidskriftsartikel (refereegranskat)
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21.
  • Barns röster om våld : att tolka och förstå
  • 2008. - 1
  • Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
    • Den här boken har två syften. Det första är att utifrån aktuell forskning inom området ge en inblick i kvalitativa, tolkande perspektiv på barn som upplever våld i sin familj. Här är barnens egna röster om sina upplevelser och situation utgångspunkten. Det andra syftet är att ge en grundläggande kunskap om den "nya" barndomssociologin som teori och metod - både i praktiskt arbete med den här gruppen barn samt deras familjer och i forskning.
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23.
  • Beausang, Angela, et al. (författare)
  • "Möjligheten att rädda några av dessa kvinnors liv har inte vägts in"
  • 2014
  • Ingår i: Dagens Medicin. - : Dagens Medicin.
  • Tidskriftsartikel (populärvet., debatt m.m.)abstract
    • Namnet på Socialstyrelsens vägledning lyder: Hur upptäcka våldsutsatthet? Ja, det kan man verkligen fråga sig efter att ha läst detta föga vägledande dokument, skriver ett stort antal kritiska debattörer.
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24.
  • Berglund, Gunilla, et al. (författare)
  • "Between Men" : A psychosocial rehabilitation programme for men with prostate cancer
  • 2007
  • Ingår i: Acta Oncologica. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 46:1, s. 83-89
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to evaluate the effect of psychosocial rehabilitation on newly diagnosed prostate cancer patients. The “Between Men” programme consisted of seven weekly sessions of physical training (Phys) alone, information (Info) alone or physical training plus information (PhysInfo). After diagnoses, patients (n =211) were consecutively included, stratified and randomised to one of four groups: Phys, Info, PhysInfo or standard care control (C). A nurse specialised in urology, an urologist and a physiotherapist performed the interventions. Patients were followed up during one year with mailed standardised questionnaires. It could not be assumed that the “Between Men” programme had any effect on patients’ anxiety and depression (HADS). Health-related quality of life (HRQOL) was associated with stage of disease but not with psychosocial intervention. Thus, Physical Function (PF), Role Function (RF) and Fatigue (FA) were inferior among patients with, than without, metastases of prostate cancer both at baseline and at the 12-month follow-up. This randomized study did not demonstrate any significant effect of psychosocial rehabilitation among prostate cancer patients. Considering the low rate (1/2), of included/eligible patients a less complicated design (intervention versus control) would have been preferred in order to increase power.
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27.
  • Bergstrom, Aileen, et al. (författare)
  • Association between satisfaction and participation in everyday occupations after stroke
  • 2017
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 24:5, s. 339-348
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Within occupational therapy, it is assumed that individuals are satisfied when participating in everyday occupations that they want to do. However, there is little empirical evidence to show this. Aims: The aim of this study is to explore and describe the relation between satisfaction and participation in everyday occupations in a Swedish cohort, 5 years post stroke. Methods: Sixty-nine persons responded to the Occupational Gaps Questionnaire (OGQ). The questionnaire measures subjective restrictions in participation, i.e. the discrepancy between doing and wanting to do 30 different occupations in everyday life, and satisfaction per activity. Results were analysed with McNemar/chi-square. Results: Seventy percent of the persons perceived participation restrictions. Individuals that did not perceive restrictions in their participation had a significantly higher level of satisfaction (p=.002) compared to those that had restrictions. Participants that performed activities that they wanted to do report between 79 and 100% satisfaction per activity. Conclusion: In this cohort, there was a significant association between satisfaction and participating in everyday occupations one wants to do, showing that satisfaction is an important aspect of participation and substantiates a basic assumption within occupational therapy. The complexity of measuring satisfaction and participation in everyday occupations is discussed.
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28.
  • Bergstrom, Aileen L., et al. (författare)
  • Perceived occupational gaps one year after stroke : An explorative study
  • 2012
  • Ingår i: Journal of Rehabilitation Medicine. - Uppsala : Medical Journals Sweden AB. - 1650-1977 .- 1651-2081. ; 44:1, s. 36-42
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To explore and describe factors associated with occupational gaps and to identify factors at 3 months that predict occupational gaps one year post-stroke. A gap, a restriction in participation, is considered to be present when there is a discrepancy between what the individual wants to do and what they actually do in everyday life. Design: Prospective longitudinal study. Subjects: Two hundred persons with stroke. Methods: Data from the Occupational Gaps Questionnaire, one year post-stroke, was used as the dependent variable in 3- and 12-month regression analyses. Domains of the Stroke Impact Scale, global life satisfaction, demographic and medical factors were used as independent variables. Results: At 3 months, activities of daily living abilities, social participation and not being born in Sweden predicted occupational gaps at 12 months. Stroke severity and not being born in Sweden and 3 factors at 12 months: social participation, self-rated recovery, and global life satisfaction were associated with occupational gaps. Conclusion: Activities of daily living ability at 3 months predicted occupational gaps after stroke. Thus, it is possible to identify early on, and provide interventions for, those that risk participation restrictions. Not being born in the country might be an indicator of a risk for participation restrictions.
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30.
  • Bergström, Aileen L., et al. (författare)
  • Combined life satisfaction of persons with stroke and their caregivers : associations with caregiver burden and the impact of stroke
  • 2011
  • Ingår i: Health and Quality of Life Outcomes. - : Springer Science and Business Media LLC. - 1477-7525. ; 9, s. 1-
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Little is known about the life satisfaction of the person with stroke combined with their caregiver, i.e. the dyad, despite the fact that life satisfaction is an important rehabilitation outcome. The aim of this study was to describe the dyads combined life satisfaction and to understand this in relationship to the perceived impact of stroke in everyday life and caregiver burden. Methods: In this cross-sectional study, the life satisfaction of persons and their informal caregivers was measured in 81 dyads one year post stroke. Their global life satisfaction, measured with LiSat-11, was combined to a dyad score and the dyads were then categorized as satisfied, dissatisfied or discordant. The groups were compared and analyzed regarding levels of caregiver burden, measured with the Caregiver Burden scale, and the perceived impact of stroke in everyday life, measured with the Stroke Impact Scale (SIS). Results: The satisfied dyads comprised 40%, dissatisfied 26% and those that were discordant 34%. The satisfied dyads reported a significantly lower impact of the stroke in everyday life compared with the dyads that were not satisfied. As expected, dyads that were not satisfied reported a significantly greater caregiver burden compared with the satisfied dyads. The discordant group was further broken down into a group of dissatisfied and satisfied caregivers. The caregivers that were not satisfied in the discordant group perceived a significantly greater level of caregiver burden compared with the satisfied group. Even caregivers who were satisfied with life but whose care recipients were not satisfied reported caregiver burden. Conclusions: Measuring combined life satisfaction provides a unique focus and appears to be a feasible way of attaining the dyads' perspective. The findings suggest that those dyads with a discordant life satisfaction could be vulnerable because of the caregivers' reported caregiver burden. These findings support the importance of a dyadic perspective and add to the understanding of the reciprocal influences between the caregiver and recipient. This knowledge has clinical implications and contributes to the identification of possible vulnerable dyads in need of tailored support.
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31.
  • Bergström, Aileen L., et al. (författare)
  • Complex negotiations : The lived experience of enacting agency after a stroke
  • 2015
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 22:1, s. 43-53
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: This qualitative, longitudinal, descriptive study aimed to understand the lived experience of enacting agency, and to describe the phenomenon of agency and the meaning structure of the phenomenon during the year after a stroke. Agency is defined as making things happen in everyday life through one's actions. Methods: This study followed six persons (three men and three women, ages 63 to 89), interviewed on four separate occasions. Interview data were analysed using the Empirical Phenomenological Psychological method. Results: The main findings showed that the participants experienced enacting agency in their everyday lives after stroke as negotiating different characteristics over a span of time, a range of difficulty, and in a number of activities, making these negotiations complex. The four characteristics described how the participants made things happen in their everyday lives through managing their disrupted bodies, taking into account their past and envisioning their futures, dealing with the world outside themselves, and negotiating through internal dialogues. Conclusions: This empirical evidence regarding negotiations challenges traditional definitions of agency and a new definition of agency is proposed. Understanding clients' complex negotiations and offering innovative solutions to train in real-life situations may help in the process of enabling occupations after a stroke.
  •  
32.
  • Bergström, Aileen L., et al. (författare)
  • Participation in everyday life and life satisfaction in persons with stroke and their caregivers 3–6 months after onset
  • 2015
  • Ingår i: Journal of Rehabilitation Medicine. - : Medical Journals Sweden AB. - 1650-1977 .- 1651-2081. ; 47:6, s. 508-515
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To explore and describe persons with stroke and their caregivers' restrictions in participation in everyday occupations, i.e. occupational gaps, 3-6 months post-stroke, in relation to life satisfaction, combined life satisfaction, caregiver burden, perceived impact of stroke, and activities of daily living. Design: Cross-sectional study. Subjects: Persons with stroke and their caregivers (105 dyads). Methods: The Occupational Gaps Questionnaire, Life Satisfaction Checklist, Caregiver Burden Scale, Stroke Impact Scale and Barthel Index were used. Correlations were analysed with Spearman's rank, and regression analyses used life satisfaction as the dependent variable. Results: At least one person in 86% of the dyads perceived restrictions in participation, with the most common gap in travelling for pleasure. Correlations were low between the numbers of occupational gaps and life satisfaction (R=-0.33, R=-0.31); however, life satisfaction accounted for occupational gaps both for persons with stroke and for caregivers. A greater number of occupational gaps were perceived in the dyads with combined low levels of life satisfaction compared with those with combined high levels of life satisfaction. Conclusion: Participation in everyday occupations is related to life satisfaction even for caregivers of persons with stroke. The results of this study add to our knowledge about the stroke-caregiver dyad and will help to inform family-centred approaches within stroke rehabilitation.
  •  
33.
  • Bergström, Sten-Erik, et al. (författare)
  • Asthma mortality among Swedish children and young adults, a 10-year study
  • 2008
  • Ingår i: Respiratory Medicine. - : Elsevier BV. - 0954-6111 .- 1532-3064. ; 102:9, s. 1335-1341
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Previous reports indicate that morbidity and mortality from asthma have increased during the past decades. Here, the mortality rate associated with asthma and possible risk factors in children and young adults in Sweden during the period 1994-2003 were evaluated. METHODS: The medical profession was asked to report suspected cases of death from asthma in individuals 1-34 years of age. All death certificates containing relevant ICD codes were reviewed. Medical records and autopsy reports were assessed and telephone interviews with next-of-kin performed. RESULTS: During the 10-year period 37 deaths due to asthma were identified. The median age at the time of death was 27 years and 6 of the deceased were younger than 15. The overall incidence of death from asthma decreased from 1.54 deaths per million in 1994 to 0.53 per million in 2003. Common risk factors were under-treatment (23/37), poor adherence to prescribed treatment (17/37) and adverse psychosocial situation (19/37). An alarming finding was that 11 of the 37 deaths were probably caused by food allergy and for 8 subjects death was associated with exposure to pet dander. The death certificates were found to contain inaccuracies with 30% of those for whom asthma was reported as the underlying cause having died from other causes. CONCLUSION: Asthma mortality in children and young adults in Sweden decreased between 1994 and 2003. Food allergy and inadequate treatment were the major risk factors for such a death. Recognition and special care of patients with asthma who have shown signs of non-compliance, denial or severe food allergy must be encouraged.
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34.
  • Bertilsson, Ann-Sofie, et al. (författare)
  • A client-centred ADL intervention: three-month follow-up of a randomized controlled trial
  • 2014
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 21, s. 377-391
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The aim was to study a client-centred activities of daily living (ADL) intervention (CADL) compared with the usualADL intervention (UADL) in people with stroke regarding: independence in ADL, perceived participation, life satisfaction,use of home-help service, and satisfaction with training and, in their significant others, regarding: caregiver burden, lifesatisfaction, and informal care. Methods: In this multicentre study, 16 rehabilitation units were randomly assigned to deliverCADL or UADL. The occupational therapists who provided the CADL were specifically trained. Eligible for inclusion werepeople with stroke treated in a stroke unit £3 months after stroke, dependent in ‡two ADL, not diagnosed with dementia, andable to understand instructions. Data were collected at inclusion and three months thereafter. To detect a significant differencebetween the groups in the Stroke Impact Scale (SIS) domain “participation”, 280 participants were required. Intention-totreatanalysis was applied. Results: At three months, there was no difference in the outcomes between the CADL group(n = 129) and the UADL group (n = 151), or their significant others (n = 87/n = 93) except in the SIS domain “emotion” infavour of CADL (p = 0.04). Conclusion: The CADL does not appear to bring about short-term differences in outcomes andlonger follow-ups are required.
  •  
35.
  • Bertilsson, Ann Sofie, et al. (författare)
  • A cluster randomized controlled trial of a client-centred, activities of daily living intervention for people with stroke : One year follow-up of caregivers
  • 2016
  • Ingår i: Clinical Rehabilitation. - : SAGE Publications. - 0269-2155 .- 1477-0873. ; 30:8, s. 765-775
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: Compare caregiver burden, provision of informal care, participation in everyday occupations and life satisfaction of caregivers to people with stroke, who either had received a client-centred, activities of daily living intervention or usual activities of daily living interventions. Design: A multicentre cluster randomized controlled trial in which 16 rehabilitation units were randomly assigned to deliver a client-centred, activities of daily living intervention or usual activities of daily living interventions. Caregiver outcomes were compared cross-sectionally at 12 months and changes in outcomes between three and 12 months after people with stroke were included in the study. Setting: Inpatient and outpatient rehabilitation. Participants: Caregivers of people with stroke enrolled in the trial. Intervention: A client-centred, activities of daily living intervention aiming to increase agency in daily activities and participation in everyday life for people after stroke. Main measures: Caregiver Burden Scale, Occupational Gaps Questionnaire, LiSat-11. Results: There were no differences in outcomes between caregivers in the client-centred, activities of daily living (n = 88) and the usual activities of daily living (n = 95) group at 12 months. The caregiver burden score was 42.7 vs. 41.8, p = 0.75, mean occupational gaps were 3.5 vs. 4.0, p = 0.52 and satisfaction with life was 53% vs. 50%, p = 0.87. There were no differences in changes between three and 12 months. However, within groups there were significant differences in caregiver burden, factor general strain, for caregivers in the client-centred, activities of daily living group, and in provision of informal care for the usual activities of daily living group. Conclusion: The client-centred intervention did not bring about any difference between caregiver-groups, but within groups some difference was found for caregiver burden and informal care.
  •  
36.
  • Borglin, Gunilla, 1959-, et al. (författare)
  • Registered nurses' experiences of providing respiratory care in relation to hospital aquired pneumonia at in-patient stroke units: a qualitative descriptive study
  • 2020
  • Ingår i: BMC Nursing. - : BioMed Central. - 1472-6955. ; 19:124, s. 1-11
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: This study aimed to describe registered nurses’ (RNs) experiences of providing respiratory care in relation to hospital acquired pneumonia (HAP), specifically among patients with acute stroke being cared for at in-patient stroke units. Background: One of the most common and serious respiratory complications associated with acute stroke is HAP. Respiratory care is among the fundamentals of patient care, and thus competency in this field is expected as part of nursing training. However, there is a paucity of literature detailing RNs’ experiences with respiratory care in relation to HAP, specifically among patients with acute stroke, in the context of stroke units. As such, there is a need to expand the knowledge base relating to respiratory care focusing on HAP, to assist with evidence-based nursing.Design: A qualitative descriptive study.Method: Eleven RNs working in four different acute stroke units in Southern Sweden participated in the current study. The data were collected through semi-structured interviews, and the transcribed interviews were analysed using inductive content analysis.Results: Three overarching categories were identified: (1), awareness of risk assessments and risk factors for HAP (2) targeting HAP through multiple nursing care actions, and (3) challenges in providing respiratory care to patients in risk of HAP. These reflected the similarities and differences in the experiences that RNs had with providing respiratory care in relation to HAP among in-patients with acute stroke.Conclusions: The findings from this study suggest that the RNs experience organisational challenges in providing respiratory care for HAP among patients with acute stroke. Respiratory care plays a vital role in the identification and prevention of HAP, but our findings imply that RNs’ knowledge needs to be improved, the fundamentals of nursing care need to be prioritised, and evidence-based guidelines must be implemented. RNs would also benefit from further education and support, in order to lead point-of-care nursing in multidisciplinary stroke teams.
  •  
37.
  • Carlsson, Per-Ola, et al. (författare)
  • Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
  • 2018
  • Ingår i: American Journal of Transplantation. - : Elsevier BV. - 1600-6135 .- 1600-6143. ; 18:7, s. 1735-1744
  • Tidskriftsartikel (refereegranskat)abstract
    • Macroencapsulation devices provide the dual possibility to immunoprotect transplanted cells while also being retrievable; the latter bearing importance for safety in future trials with stem-cell derived cells. However, macroencapsulation entails a problem with oxygen supply to the encapsulated cells. The βAir device solves this with an incorporated refillable oxygen tank. This phase 1 study evaluated the safety and efficacy of implanting the βAir device containing allogeneic human pancreatic islets to patients with type 1 diabetes. Four patients were transplanted with 1-2 βAir devices, each containing 155000-180000 IEQ (i.e. 1800-4600 IEQ per kg body weight), and monitored for 3-6 months, followed by the recovery of devices. Implantation of the βAir device was safe and successfully prevented immunization and rejection of the transplanted tissue. However, although beta cells survived in the device, only minute levels of circulating C-peptide were observed with no impact on metabolic control. Fibrotic tissue with immune cells was formed in capsule surroundings. Recovered devices displayed a blunted glucose-stimulated insulin response, and amyloid formation in the endocrine tissue. We conclude that the βAir device is safe and can support survival of allogeneic islets for several months, although the function of the transplanted cells was limited.
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38.
  • Chang, Ya-Ting, et al. (författare)
  • Versican accumulates in vascular lesions in pulmonary arterial hypertension
  • 2016
  • Ingår i: PULMONARY CIRCULATION. - : Wiley. - 2045-8932 .- 2045-8940. ; 6:3, s. 347-359
  • Tidskriftsartikel (refereegranskat)abstract
    • Pulmonary arterial hypertension (PAH) is a lethal condition for which there is no effective curative pharmacotherapy. PAH is characterized by vasoconstriction, wall thickening of pulmonary arteries, and increased vascular resistance. Versican is a chondroitin sulfate proteoglycan in the vascular extracellular matrix that accumulates following vascular injury and promotes smooth-muscle cell proliferation in systemic arteries. Here, we investigated whether versican may play a similar role in PAH. Paraffin-embedded lung sections from patients who underwent lung transplantation to treat PAH were used for immunohistochemistry. The etiologies of PAH in the subjects involved in this study were idiopathic PAH, scleroderma, and congenital heart disease (atrial septal defect) with left-to-right shunt. Independent of the underlying etiology, increased versican immunostaining was observed in areas of medial thickening, in neointima, and in plexiform lesions. Western blot of lung tissue lysates confirmed accumulation of versican in patients with PAH. Double staining for versican and CD45 showed only occasional colocalization in neointima of high-grade lesions and plexiform lesions. In vitro, metabolic labeling with [S-35] sulfate showed that human pulmonary artery smooth-muscle cells (hPASMCs) produce mainly chondroitin sulfate glycosaminoglycans. In addition, hypoxia, but not cyclic stretch, was demonstrated to increase both versican messenger RNA expression and protein synthesis by hPASMCs. Versican accumulates in vascular lesions of PAH, and the amount of versican correlates more with lesion severity than with underlying etiology or inflammation. Hypoxia is a possible regulator of versican accumulation, which may promote proliferation of pulmonary smooth-muscle cells and vascular remodeling in PAH.
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39.
  • Crippa, Alessio, et al. (författare)
  • The ProBio trial : molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer
  • 2020
  • Ingår i: Trials. - : BioMed Central. - 1745-6215. ; 21:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Multiple therapies exist for patients with metastatic castration-resistant prostate cancer (mCRPC). However, their improvement on progression-free survival (PFS) remains modest, potentially explained by tumor molecular heterogeneity. Several prognostic molecular biomarkers have been identified for mCRPC that may have predictive potential to guide treatment selection and prolong PFS. We designed a platform trial to test this hypothesis.Methods: The Prostate-Biomarker (ProBio) study is a multi-center, outcome-adaptive, multi-arm, biomarker-driven platform trial for tailoring treatment decisions for men with mCRPC. Treatment decisions in the experimental arms are based on biomarker signatures defined as mutations in certain genes/pathways suggested in the scientific literature to be important for treatment response in mCRPC. The biomarker signatures are determined by targeted sequencing of circulating tumor and germline DNA using a panel specifically designed for mCRPC.Discussion: Patients are stratified based on the sequencing results and randomized to either current clinical practice (control), where the treating physician decides treatment, or to molecularly driven treatment selection based on the biomarker profile. Outcome-adaptive randomization is implemented to early identify promising treatments for a biomarker signature. Biomarker signature-treatment combinations graduate from the platform when they demonstrate 85% probability of improving PFS compared to the control arm. Graduated combinations are further evaluated in a seamless confirmatory trial with fixed randomization. The platform design allows for new drugs and biomarkers to be introduced in the study.Conclusions: The ProBio design allows promising treatment-biomarker combinations to quickly graduate from the platform and be confirmed for rapid implementation in clinical care.
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40.
  • Dahlkild-Öhman, Gunilla, 1945- (författare)
  • Att börja tala med barn om pappas våld mot mamma : Radikalt lärande i arbetet med vårdnad, boende och umgänge
  • 2011
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • This thesis explores the scope for children’s voices offered to children in court mandated investigations regarding custody, residence or contact. The focus is on children who have been exposed to their father’s violence against their mother The aim is to study how the legislators’ intentions concerning children’s participation in this area are implemented in work groups. The assumption is that implementation can be seen as collective learning. Implementation may in this case challenge established relations of power like age and gender orders. Professional discourses on violence have to shift from gender neutral to gendered discourses and discourses on children have to include a participation discourse. Learning which includes a shift in discourses and challenges established power relations is defined as radical learning.The approach is social constructionist and draws on group interviews with social workers specialized in family law.The thesis analyses which discourses of violence and of children are accessible and used at group level. This can be seen as a discursive opportunity structure. The discourses in question are: gender violence, child protection, treatment and family law discourses as well as care and participation discourses. The conclusion is that all these discourses are accessible to the professionals and the effects of the different discourses are discussed regarding the possibilities for creating a safe situation for mother and child during the investigation.The thesis furthermore analyses the organisation of the work groups. These characteristics can be seen as an organisational opportunity structure. The analysis shows different patterns in the groups when it comes to structure and stage of learning process. One group seems to be at the stage where the members are prepared to start talking to the child about the father’s violence.The final chapter presents a discussion of radical learning and the possibilities for radical social change when established power relations are challenged.
  •  
41.
  • Dahlkild-Öhman, Gunilla, et al. (författare)
  • Inequality regimes and men’s positions in social work
  • 2013
  • Ingår i: Gender, Work and Organization. - : Wiley. - 0968-6673 .- 1468-0432. ; 20:1, s. 85-99
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this article is to contribute to the exploration of men’s positions in professions numerically dominated by women through an in depth analysis of the gendering practices in groups of social workers. The empirical material consists of interviews with three work groups in Sweden, each with one man and several women as members. The analysis focuses upon gendering practices in the interview setting. It shows how the positions occupied by the men in the sample confirm or undermine constructions of masculinity as dominance. Furthermore, it is argued that to fully understand men’s positions in these groups the analysis needs take other forms of inequality into account in addition to gender. It is shown that in the empirical cases under scrutiny men’s positions are shaped by regimes of inequality where age and gender relations, as well as notions of professional experience, are interconnected.
  •  
42.
  • Dahlkild-Öhman, Gunilla, et al. (författare)
  • Konstruktion av risk och barns utsatthet inom olika domäner av politik och praktik : familjerättens möte med barn vars pappa misshandlar mamma
  • 2006
  • Konferensbidrag (refereegranskat)abstract
    • Detta paper presenterar preliminära resultat från ett pågående explorativt forskningsprojekt om barn som sociala aktörer i möten med familjerätten. I fokus står barn som upplevt pappas våld mot mamma. Sedan 1996 åligger det den som vid en rättslig tvist mellan ett barns föräldrar verkställer en utredning om vårdnad, boende och umgänge att, om det inte är direkt olämpligt, undersöka ”barnets inställning” och redovisa den inför rätten. Det finns för närvarande en begränsad kunskap om hur barns upplevelser av våld hanteras i dessa utredningar. Syftet med projektet är att ge en fördjupad kunskap om utsatta barns deltagande i familjerättsliga utrednings-processer. De resultat som presenteras här gäller utredares konstruktioner av utsatthet och risker för barn som upplevt pappas våld mot mamma. Vi diskuterar i vad mån dessa konstruktioner kan förstås som uttryck för dominerande diskurser inom fyra olika domäner av politik-praktik i Sverige idag: ”våld i nära relationer”; ”barnskydd”, ”vårdnad, boende, umgänge” respektive ”behandling”.
  •  
43.
  • Dahlkild-Öhman, Gunilla, et al. (författare)
  • Konstruktion av risk och barns utsatthet inom olika domäner av politik och praktik: Familjerättens möte med barn vars pappa misshandlar mamma : Paper presenterat vid Forskningskonferens 8-10 november 2006 om Utsatt barndom, sårbara familjer och samhällets insatser
  • 2006
  • Konferensbidrag (refereegranskat)abstract
    • Detta paper presenterar preliminära resultat från ett pågående explorativt forskningsprojekt om barn som sociala aktörer i möten med familjerätten. I fokus står barn som upplevt pappas våld mot mamma. Sedan 1996 åligger det den som vid en rättslig tvist mellan ett barns föräldrar verkställer en utredning om vårdnad, boende och umgänge att, om det inte är direkt olämpligt, undersöka ”barnets inställning” och redovisa den inför rätten. Det finns för närvarande en begränsad kunskap om hur barns upplevelser av våld hanteras i dessa utredningar. Syftet med projektet är att ge en fördjupad kunskap om utsatta barns deltagande i familjerättsliga utrednings-processer. De resultat som presenteras här gäller utredares konstruktioner av utsatthet och risker för barn som upplevt pappas våld mot mamma. Vi diskuterar i vad mån dessa konstruktioner kan förstås som uttryck för dominerande diskurser inom fyra olika domäner av politik-praktik i Sverige idag: ”våld i nära relationer”; ”barnskydd”, ”vårdnad, boende, umgänge” respektive ”behandling”.
  •  
44.
  • Dahlkild-Öhman, Gunilla, et al. (författare)
  • Work group characteristics and professional learning processes in the field of men’s violence to women
  • 2007
  • Konferensbidrag (populärvet., debatt m.m.)abstract
    • The paper is based upon ongoing research on professionals’ conversations with children in legal conflicts regarding child custody, contact or residence, with particular focus on children whose father is violent to the mother. Drawing upon group interviews with staff at four work places in Sweden specialised in family law investigations and mediation, we outline different work group characteristics, and discuss what these may mean for learning processes regarding a topic relatively new to the profession, such as men’s violence to women and children’s position in these families. It is argued that the types of groups identified – ‘homogenous and maintaining’, ‘heterogeneous and maintaining’, and ‘homogenous and development-oriented’ may represent different stages of a learning process in this field. Furthermore, that work group characteristics may enable or obstruct further change in a somewhat surprising pattern. We also link the different types of work groups and their learning processes to the wider societal context, specifically discursive shifts in Sweden as regards family law and men’s violence to women.
  •  
45.
  • Dahlkild-Öhman, Gunilla, et al. (författare)
  • Work group characteristics and professional learning processes in the field of men’s violence to women : Paper presented at 8th conference of the European Sociological Association, Glasgow, 3-6 September 2007
  • 2007
  • Konferensbidrag (populärvet., debatt m.m.)abstract
    • The paper is based upon ongoing research on professionals’ conversations with children in legal conflicts regarding child custody, contact or residence, with particular focus on children whose father is violent to the mother. Drawing upon group interviews with staff at four work places in Sweden specialised in family law investigations and mediation, we outline different work group characteristics, and discuss what these may mean for learning processes regarding a topic relatively new to the profession, such as men’s violence to women and children’s position in these families. It is argued that the types of groups identified – ‘homogenous and maintaining’, ‘heterogeneous and maintaining’, and ‘homogenous and development-oriented’ may represent different stages of a learning process in this field. Furthermore, that work group characteristics may enable or obstruct further change in a somewhat surprising pattern. We also link the different types of work groups and their learning processes to the wider societal context, specifically discursive shifts in Sweden as regards family law and men’s violence to women.
  •  
46.
  • Dahlqvist, Vera, et al. (författare)
  • Development of the perceptions of conscience questionnaire.
  • 2007
  • Ingår i: Nursing Ethics. - : SAGE Publications. - 0969-7330 .- 1477-0989. ; 14:2, s. 181-193
  • Tidskriftsartikel (refereegranskat)abstract
    • Health care often involves ethically difficult situations that may disquiet the conscience. The purpose of this study was to develop a questionnaire for identifying various perceptions of conscience within a framework based on the literature and on explorative interviews about perceptions of conscience (Perceptions of Conscience Questionnaire). The questionnaire was tested on a sample of 444 registered nurses, enrolled nurses, nurses' assistants and physicians. The data were analysed using principal component analysis to explore possible dimensions of perceptions of conscience. The results showed six dimensions, found also in theory and empirical health care studies. Conscience was perceived as authority, a warning signal, demanding sensitivity, an asset, a burden and depending on culture. We conclude that the Perceptions of Conscience Questionnaire is valid for assessing some perceptions of conscience relevant to health care providers.
  •  
47.
  • Dalheim Englund, Ann-Charlotte, et al. (författare)
  • Life without professional work : perceptions about one’s self, interpersonal relations and social life after retirement
  • 2019
  • Ingår i: Healthy Aging Research. - : Wolters Kluwer. - 2261-7434. ; 8:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study is to understand how healthy, older adults in Sweden perceive their life situation after retirement. The study is based on a lifeworld approach, and a phenomenographic method was used. Eighteen participants were interviewed, and data were analysed according to the phenomenographic principle of qualitatively different categories. Two categories were developed. The first category, “perceptions that draw attention inward, towards one’s self”, was further described in three subcategories: Sense of decreased status in society, the desire to keep aging at a distance, and contemplation of one’s own existence. The second category, “perceptions that draw attention outward, away from one’s self” was further described in the following four subcategories: caretaking of family members, involvement in social relationships, finding of deep meaning in animals and nature and engagement with society. In the discussion, the findings are further illuminated through comparisons with concepts such as maturity, wisdom and gerotranscendence, and reflections on the findings ‘relevance to a caring context follow. The conclusion suggests this study can provide knowledge that will allow healthcare providers to bridge the gap between generations in order to provide high-quality care. However, for a more profound caring dialogue, for example, about the end of life, a deeper analysis is required.
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48.
  •  
49.
  •  
50.
  • Dury, Jack, 1993- (författare)
  • Dealing With Reservoir Effects in Human and Faunal Skeletal Remains : Understanding the radiocarbon dating of aquatic samples
  • 2021
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Archaeology relies on the ordering of past events to study cultural developments. This has traditionally been achieved by looking at the stratigraphic depths of materials relative to one another. In this way, chronologies of past technological progressions and stylistic changes can be built. The introduction of radiocarbon dating in the 1950s revolutionised archaeology, allowing for direct, numerical estimates of a sample’s age. This allowed for more detailed past chronologies than was previously possible. Radiocarbon dating utilises the radioactive decay of carbon-14 (radiocarbon, 14C) to estimate a sample’s age with older samples having less 14C. Shortly after the introduction of radiocarbon dating, however, it was demonstrated that 14C is not evenly distributed globally. Typically, there is less 14C in marine (and sometimes freshwater) systems compared to the atmosphere. This results in aquatic samples appearing older than they are, a phenomenon known as a ‘reservoir effect’. When radiocarbon dating material from archaeological sites with marine activity, this is an important consideration. With aquatic resources being vital for human populations across the globe and for millennia, the ability to interpret aquatic radiocarbon dates is incredibly important. Making use of radiocarbon dates without properly handling any reservoir effects have proved problematic, sometimes resulting in archaeologically incorrect chronologies being constructed. Reservoir effects can, however, be managed. This thesis demonstrates how archaeologists should interpret radiocarbon dates from aquatic samples, avoiding erroneously-old age estimates. Through careful sample selection, considering complicated carbon source mixing, measuring the scale and variability of reservoir effects within a single ecosystem and using prior knowledge about a sample’s age, the dating of aquatic material can be greatly improved. This thesis also details a novel method of dating teeth, reducing uncertainty, and concomitantly estimating the extent of the reservoir effect. This was achieved by dating dental increments, combined with complex modelling. It is clear that there is no single method of handling reservoir effects, and methods for dealing with reservoir effects will differ depending on the archaeological site and specific research question. In this thesis, novel and existing methods of dealing with reservoir effects are demonstrated by considering five case studies from four archaeological sites:At the site of Hamanaka 2 (Rebun Island, Japan), it is demonstrated that by carefully selecting samples without reservoir effects, the dating of the stratigraphy of the site can be accurately modelled. Concerning the cemetery site of Rounala (northern Sweden), it is demonstrated that by carefully reconstructing complex human diets, the dating of humans can be modelled to a high resolution. This has implications for the understanding of the Church’s relationship with the cemetery. At the site of Ekven (Chukotka, Bering Strait) reservoir effect variability between species is carefully described. A more detailed understanding of regional reservoir effects allows for more accurate dating of human remains from the marine hunting Old Bering Sea culture. More accurate dating of human remains allows for the refining of existing Old Bering Sea culture chronologies. Finally, concerning the material from Resmo (Ӧland, Sweden), a novel dental wiggle matching model is presented as a possible method for reducing dating uncertainty in individuals with a marine dietary component.
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