| 1. |
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| 2. |
- Ahl, David, et al.
(författare)
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Turning Up the Heat : Local Temperature Control During in vivo Imaging of Immune Cells
- 2019
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Ingår i: Frontiers in Immunology. - : FRONTIERS MEDIA SA. - 1664-3224. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- Intravital imaging is an invaluable tool for studying the expanding range of immune cell functions. Only in vivo can the complex and dynamic behavior of leukocytes and their interactions with their natural microenvironment be observed and quantified. While the capabilities of high-speed, high-resolution confocal and multiphoton microscopes are well-documented and steadily improving, other crucial hardware required for intravital imaging is often developed in-house and less commonly published in detail. In this report, we describe a low-cost, multipurpose, and tissue-stabilizing in vivo imaging platform that enables sensing and regulation of local tissue temperature. The effect of tissue temperature on local blood flow and leukocyte migration is demonstrated in muscle and skin. Two different models of vacuum windows are described in this report, however, the design of the vacuum window can easily be adapted to fit different organs and tissues.
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| 3. |
- Björklund, Fredrik, et al.
(författare)
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Recent Work on Motivational Internalism
- 2012
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Ingår i: Analysis. - Oxford, UK : Oxford University Press (OUP). - 0003-2638 .- 1467-8284. ; 72:1, s. 124-137
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Forskningsöversikt (refereegranskat)abstract
- Reviews recent work on motivational internalism.
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| 4. |
- Björnsson, Gunnar, 1969, et al.
(författare)
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Motivational internalism and folk intuitions
- 2015
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Ingår i: Philosophical Psychology. - : Informa UK Limited. - 1465-394X .- 0951-5089. ; 28:5, s. 715-734
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Tidskriftsartikel (refereegranskat)abstract
- Motivational internalism postulates a necessary connection between moral judgments and motivation. In arguing for and against internalism, metaethicists traditionally appeal to intuitions about cases, but crucial cases often yield conflicting intuitions. One way to try to make progress, possibly uncovering theoretical bias and revealing whether people have conceptions of moral judgments required for noncognitivist accounts of moral disagreement, is to investigate non-philosophers’ willingness to attribute moral judgments. A pioneering study by Shaun Nichols seemed to undermine internalism, as a large majority of subjects were willing to attribute moral understanding to an agent lacking moral motivation. However, our attempts to replicate this study yielded quite different results, and we identified a number of problems with Nichols’ experimental paradigm. The results from a series of surveys designed to rule out these problems (a) show that people are more willing to attribute moral understanding than moral belief to agents lacking moral motivation, (b) suggest that a majority of subjects operate with some internalist conceptions of moral belief, and (c) are compatible with the hypothesis that an overwhelming majority of subjects do this. The results also seem to suggest that if metaethicists’ intuitions are theoretically biased, this bias is more prominent among externalists.
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| 5. |
- Danvind, Jonas, et al.
(författare)
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Calibration of a constitutive model for diffusive moisture transport in wood using data from X-ray CT-scanning and digital speckle photography
- 2004
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Ingår i: 5th Conference on Timber drying for value-added prducts, COST action E15 "advances in drying of wood". ; , s. 210-218
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- An unsteady-state diffusion model is applied for studying wood drying below the fibre saturation point. The moisture diffusion coefficient in Fick's law for Norway spruce under isothermal drying conditions is determined. Using X-ray CT-scanning and Digital Speckle Photography, the wood density and moisture content are obtained in the radial direction of the wood samples. An optimization scheme is used to minimize the difference between observed and computed moisture content in order to calibrate the values of a set of parameters describing the diffusion coefficient. In this study the values of the parameters for a parameterization of Arrhenius' type are determined. The general idea discussed, however, is not limited to a specific model, butcan be used for a wide class of parameter identification problems. The results show a good agreement between observed and computed moisture content and it is concluded that the numerical realization of the optimization scheme works well. Nevertheless, the value of the diffusion coefficient is somewhat higher than expected. This is likely the consequence of a permeable coating of the samples.
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| 6. |
- Engström, Gunnar, et al.
(författare)
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Pulmonary function and atherosclerosis in the general population : causal associations and clinical implications
- 2024
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Ingår i: European Journal of Epidemiology. - : Springer Nature. - 0393-2990 .- 1573-7284. ; 39:1, s. 35-49
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Tidskriftsartikel (refereegranskat)abstract
- Reduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50–64 years. The results were confirmed using 2-sample Mendelian randomization. Lower lung function and emphysema were associated with more atherosclerosis, but these relationships were attenuated after adjustment for cardiovascular risk factors. Lung function was not associated with coronary atherosclerosis in 14,524 never-smokers. No potentially causal effect of lung function on atherosclerosis, or vice versa, was found in the 2-sample Mendelian randomization analysis. Here we show that reduced lung function and atherosclerosis are correlated in the population, but probably not causally related. Assessing lung function in addition to conventional cardiovascular risk factors to gauge risk of subclinical atherosclerosis is probably not meaningful, but low lung function found by chance should alert for atherosclerosis.
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| 7. |
- Eriksson, Carina, 1973-
(författare)
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Isolation, Synthesis and Structure-Activity Relationships of Antifeedants against the Pine Weevil, Hylobius Abietis
- 2006
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The large pine weevil, Hylobius abietis L., is a major insect pest on conifer seedlings in northern Europe. Due to its feeding newly planted trees get girdled, resulting in high seedling mortality (up to 80%). As a consequence great financial losses to the forest industry occur. Today the seedlings are protected with the pyrethroid insecticide cypermethrin. This insecticide is toxic to aquatic organisms and is, from 2010, prohibited for use in Sweden by the Swedish Chemicals Inspectorate. An alternative to insecticides is to protect the seedlings with antifeedants, compounds that, either through taste or smell or both, deter the weevils from feeding. This thesis describes the search for and the synthesis of such antifeedant compounds. Bark extracts of several woody species, known to be non-palatable to the weevil, were prepared and found to display antifeedant activity against H. abietis. The major chemical constituents of the extracts were tested for antifeedant activity. Antifeedants such as eugenol, 2-phenylethanol and benzylalcohol, but also feeding stimulants such as β-sitosterol and linoleic acid, were identified. An extract of linden bark, Tilia cordata, was shown to contain nonanoic acid, a highly active antifeedant. Other aliphatic carboxylic acids were also found to display high antifeedant activities against the weevil, both in laboratory and in field tests. The enantiomers of dihydropinidine, a piperidine alkaloid present in several conifer species, were prepared by dimethylzinc mediated allylation of 2- methyltetrahydropyridine-N-oxide. When tested in micro feeding assays, no difference in antifeedant activity was found for the enantiomers. In a field test high antifeedant activity, comparable with that of the presently used insecticide cypermethrin, was found for (±)-dihydropindine. Other naturally occurring piperidine alkaloids were synthesised and also found to display high antifeedant activities in laboratory tests. Structure-activity relationships were evaluated for methoxy substituted benzaldehydes, benzoic acids and cinnamic aldehydes, -acids, -esters and -alcohols. While the carboxylic acids were inactive or even feeding stimulants, the aldehydes were the most active antifeedants
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| 8. |
- Eriksson, John, 1973, et al.
(författare)
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A Mass-Transport Model for Drying Wood under Isothermal Conditions
- 2005
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Ingår i: 9th international IUFRO wood drying conference, Nanjing, China, August 21-26, 2005. ; 1:1, s. 51-56
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Mass transport in wood during drying is often described in terms of different periods. Depending on the current moisture content (MC) and the structure of the wood, the driving forces behind the mass transport are essentially different. Above a certain level of MC, the fibres are partially saturated and the transport of liquid (free) water occurs mainly as a consequence of capillary action. On the other hand, below the fibre saturation point, bound water within the cell walls is conveyed by diffusion, and water vapour in the lumen moves under influence of pressures. In this contribution, a unified model is presented that takes into account the transport of the different water phases. Simulation of the drying of a Norway spruce sample from about 135% to 7% MC is carried out using the finite element method (FEM). The resulting mean MC is compared with experimental observations obtained from X-ray Computed Tomography showing reasonable agreement. Possible simplifications in the model are briefly discussed as well as some aspects of the numerical implementation.
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| 9. |
- Eriksson, John, 1973, et al.
(författare)
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A Mass Transport Model for Drying Wood under Isothermal Conditions
- 2007
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Ingår i: Drying Technology. - : Informa UK Limited. - 1532-2300 .- 0737-3937. ; 25:3, s. 433-439
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Tidskriftsartikel (refereegranskat)abstract
- Mass transport in wood during drying can have different mechanisms at different periods of drying. Depending on the current moisture content (MC) and the structure of the wood, the driving forces for the mass transport are essentially different. Above the fiber saturation point (FSP), the lumens are partially saturated and the transport of liquid (free) water occurs as a consequence of capillary action. On the other hand, below the FSP, bound water within the cell walls is conveyed by diffusion, and water vapor in the lumens moves under influence of pressures gradient. Based on these considerations, a unified model is presented that takes into account the transport of the different moisture phases. Simulation of the drying of a Norway spruce sample at 50°C from about 135 to 7% MC is carried out using the finite element method (FEM). Comparison between the simulated average MC and the experimental observations obtained from X-ray computed tomography (CT) shows reasonable agreement. Possible simplifications in the model are briefly discussed as well as some aspects of the numerical implementation. Finally, the influence of absolute permeability on the average MC is studied.
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| 10. |
- Eriksson, John, 1973, et al.
(författare)
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An experimental and numerical study of the shape stability in glued columns
- 2005
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Ingår i: European Journal of Wood and Wood Products. - : Springer. - 0018-3768 .- 1436-736X. ; 63:6, s. 423-429
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Tidskriftsartikel (refereegranskat)abstract
- The study concerns the question of how the shape stability features of laminated columns of Norway spruce can be improved in terms of twist through optimal orientation of the individual laminates. Both experimental testing and numerical simulations were employed for evaluating twist stability. In all the columns studied, deformations were measured experimentally at different moisture content levels. A number of columns were also selected for numerical analysis in order to obtain a more thorough understanding of the twist behavior involved, their geometries and material properties of interest being determined. The experimental results showed the twist stability of the columns to be highly dependant upon the internal orientation of the individual laminates. It was also found that high quality columns in terms of shape stability could be manufactured, even when the center-core material has a strong twist tendency. The numerical simulations performed were in close agreement with the experimental results.
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| 11. |
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| 12. |
- Eriksson, John, 1973, et al.
(författare)
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Cognitivism and the argument from evidence non-responsiveness
- 2023
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Ingår i: Ethical Theory and Moral Practice. - 1386-2820.
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Tidskriftsartikel (refereegranskat)abstract
- Several philosophers have recently challenged cognitivism, i.e., the view that moral judgments are beliefs, by arguing that moral judgments are evidence non-responsive in a way that beliefs are not. If you believe that P, but acquire (sufficiently strong) evidence against P, you will give up your belief that P. This does not seem true for moral judgments. Some subjects maintain their moral judgments despite believing that there is (sufficiently strong) evidence against the moral judgments. This suggests that there is a mismatch between moral judgments and beliefs. This is an interesting argument. In particular, it forces the cognitivist to be more explicit about the nature of belief and the sense in which moral judgments are responsive to evidence. This paper has two aims. First, it aims to systematically examine different versions of the argument from evidence non-responsiveness. Second, it aims to outline a more nuanced understanding of the sense in which beliefs are evidence responsive that explains why the extant versions of the argument do not constitute a challenge to cognitivism.
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| 13. |
- Eriksson, John, 1973
(författare)
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Defining Lying: In Defense of the Falsity Condition
- 2011
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Ingår i: Neither/Nor: Philosophical Papers Dedicated to Erik Carlson on the Occasion of His Fiftieth Birthday. - Västerås : Edita Västra Aros. - 9789150622249 ; , s. 69-78
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 14. |
- Eriksson, John, 1973
(författare)
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Disagreement and inconsistency: a problem for orthodox expressivism
- 2022
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Ingår i: Synthese. - : Springer Science and Business Media LLC. - 0039-7857 .- 1573-0964. ; 200:5
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Tidskriftsartikel (refereegranskat)abstract
- What makes two sentences inconsistent? Expressivists understand the meaning of a sentence in terms of the mental state it expresses. In order to explain the inconsistency between two sentences, the expressivist must appeal to some inconsistency feature of the mental states expressed. A simple explanation is that two sentences, e.g., “murder is wrong” and “murder is not wrong” are inconsistent by virtue of expressing mental states that disagree. Schroeder (2008) argues that the expressivist lacks a plausible explanation of the disagreement. Baker & Woods (2015) argue that Schroeder is wrong. With these authors, I agree that expressivists have an explanation of disagreement, but this does not adequately explain why two sentences are inconsistent. The reason is that two intuitively inconsistent sentences do not necessarily express mental states that disagree. Moreover, assuming that the expressivist gives a structurally identical explanation for moral and non-moral language, the problem generalizes to non-moral language. It is also argued that the problem extends to thought. How expressivists can and should conceive of inconsistency thus remains a challenge.
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| 15. |
- Eriksson, John, 1973
(författare)
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Elaborating Expressivism: Moral judgments, Desires and Motivation
- 2014
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Ingår i: Ethical Theory and Moral Practice. - : Springer Science and Business Media LLC. - 1386-2820 .- 1572-8447. ; 17:2, s. 253-267
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Tidskriftsartikel (refereegranskat)abstract
- According to expressivism, moral judgments are desire-like states of mind. It is often argued that this view is made implausible because it isn't consistent with the conceivability of amoralists, i.e., agents who make moral judgments yet lack motivation. In response, expressivists can invoke the distinction between dispositional and occurrent desires. Strandberg (Am Philos Quart 49:81-91, 2012) has recently argued that this distinction does not save expressivism. Indeed, it can be used to argue that expressivism is false. In this paper I argue that expressivism is a much more complex thesis than Strandberg assumes. Once these complexities are acknowledged, Strandberg's arguments are rendered ineffective and expressivism rendered more plausible.
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| 16. |
- Eriksson, John, 1973
(författare)
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Explaining Disagreement: A Problem for (Some) Hybrid Expressivists
- 2015
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Ingår i: Pacific Philosophical Quarterly. - : Wiley. - 0279-0750. ; 96:1, s. 39-53
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Tidskriftsartikel (refereegranskat)abstract
- Hybrid expressivists depart from pure expressivists by claiming that moral sentences express beliefs and desires. Daniel Boisvert and Michael Ridge, two prominent defenders of hybrid views, also depart from pure expressivists by claiming that moral sentences express general attitudes rather than an attitude towards the subject of the sentence. This article argues that even if the shift to general attitudes helps solve some of the traditional problems associated with pure expressivism, a view like Ridge's, according to which the descriptive meaning is speaker relative, turns out to have problems explaining moral disagreement.
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| 17. |
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| 18. |
- Eriksson, John, 1973
(författare)
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Expressivism, attitudinal complexity and two senses of disagreement in attitude
- 2016
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Ingår i: Erkenntnis. - : Springer Science and Business Media LLC. - 0165-0106 .- 1572-8420. ; 81:4, s. 775-794
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Tidskriftsartikel (refereegranskat)abstract
- It has recently become popular to apply expressivism outside the moral domain, e.g., to truth and epistemic justification. This paper examines the prospects of generalizing expressivism to taste. This application has much initial plausibility. Many of the standard arguments used in favor of moral expressivism seem to apply to taste. For example, it seems conceivable that you and I disagree about whether chocolate is delicious although we don't disagree about the facts, which suggests that taste judgments are noncognitive attitudes rather than beliefs. However, there is also a striking difference between moral disagreements and disagreements about taste. Faced with a moral disagreement, we intuit that (at least) either party is at fault. Disagreements about taste, by contrast, are occurrences where neither party intuitively is at fault. This leads to a dilemma. On the one hand, if a disagreement in attitude is not intuited as faultless, then it seems implausible if applied to taste. If, on the other hand, a disagreement in attitude is a disagreement that we intuit as faultless, then it seems implausible if applied to the moral domain. The aim of this paper is to examine how an expressivist can avoid this dilemma.
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| 19. |
- Eriksson, John, 1973, et al.
(författare)
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Finite element analysis of coupled nonlinear heat and moisture transfer in wood
- 2006
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Ingår i: Numerical Heat Transfer, Part A Applications. - : Informa UK Limited. - 1040-7782 .- 1521-0634. ; 50:9, s. 851-864
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Tidskriftsartikel (refereegranskat)abstract
- A nonlinear model for analysing heat and moisture flow in wood during drying below the fiber saturation point is presented. The model used considers wood at a macro level without taking the various moisture transports mechanisms at the microscopic level into account. Based on the finite-element method, a coupled system of equations resulting from the adopted heat and moisture transfer equations is established and an iterative scheme is proposed. The numerical procedure is verified by a test example. In a two-dimensional analysis, the influence of the coupling on the combined heat and moisture transfer is studied for a board subjected to a typical kiln-drying condition. How well the results agree with those obtained by introducing a commonly applied simplification is discussed.
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| 20. |
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| 21. |
- Eriksson, John, 1973
(författare)
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Hybrid expressivism: how to think about meaning
- 2014
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Ingår i: Having it both ways: hybrid theories and modern metaethics / Guy Fletcher and Michael Ridge.. - New York : Oxford university press. - 9780199347582 ; , s. 149-170
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Bokkapitel (refereegranskat)
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| 22. |
- Eriksson, John, 1973, et al.
(författare)
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Matters of ambiguity: faultless disagreement, relativism and realism
- 2016
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Ingår i: Philosophical Studies. - : Springer Science and Business Media LLC. - 0031-8116 .- 1573-0883. ; 173:6, s. 1517-1536
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Tidskriftsartikel (refereegranskat)abstract
- In some cases of disagreement it seems that neither party is at fault or making a mistake. This phenomenon, so-called faultless disagreement, has recently been invoked as a key motivation for relativist treatments of domains prone to such disagreements. The conceivability of faultless disagreement therefore appears incompatible with traditional realists semantics. This paper examines recent attempts to accommodate faultless disagreement without giving up on realism. We argue that the accommodation is unsatisfactory. However, the examination highlights that "faultless" is multiply ambiguous. The more overarching purpose is to examine the consequences of this-more generally, how to think about faultless disagreement.
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| 23. |
- Eriksson, John, 1973
(författare)
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Moisture Transport and Moisture-Induced Distortions in Timber - an Experimental and Numerical Study
- 2005
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Timber products subjected to climatic variations commonly display moisture-induced distortions that can lead to serious problems for end-users. The aim of the thesis, which consists of an extended summary and six appended papers, was to investigate the potential of using the gluing technique suggested here for dealing with problems of moisture-induced distortions and developing the heat and mass transfer models which such distortion analyses require. An extensive investigation of the distortion of individual boards, laminated boards and columns was carried out. An overview of the work together with detailed information on various aspects of wood drying and of the distortion associated with it is presented. The shape stability (particularly the twist) of the timber products studied was investigated using both numerical and experimental approaches. Theories of heat and mass transfer in timber are taken up and the numerical implementation is discussed. The finite element method is utilized to solve the equations concerning the hygro-thermal-mechanical behaviour of wood that were obtained, and a method for determining material parameters needed in wood drying was developed. An adaptive procedure was employed to control the discretization error that the numerical procedure introduced, and a coupled non-linear model for predicting heat and moisture transfer during drying below the fibre saturation point is presented. For drying from an initially green condition, the moisture content predicted was compared with that estimated on the basis of CT-scanning.For the timber products studied, much better shape stability was obtained through proper orientation of the comprising laminates. The results provide support for the deformation predictions obtained through computer simulations. Material parameters of Norway spruce were determined, some of them being a function both of moisture content and of temperature. The theoretical predictions of moisture content agreed reasonably well with those obtained experimentally both above and below the fibre saturation point. The diffusion coefficient determined by optimisation was in accordance with values reported in the literature.
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| 24. |
- Eriksson, John, 1973, et al.
(författare)
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Moral Judgments, Cognitivism and the Dispositional Nature of Belief: Why Moral Peer Intransigence is Intelligible
- 2021
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Ingår i: Philosophia. - : Springer Science and Business Media LLC. - 0048-3893 .- 1574-9274. ; 49, s. 1753-1766
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Tidskriftsartikel (refereegranskat)abstract
- Richard Rowland has recently argued that considerations based on moral disagreement between epistemic peers give us reason to think that cognitivism about moral judgments, i.e., the thesis that moral judgments are beliefs, is false. The novelty of Rowland's argument is to tweak the problem descriptively, i.e., not focusing on what one ought to do, but on what disputants actually do in the light of peer disagreement. The basic idea is that moral peer disagreement is intelligible. However, if moral judgments were beliefs, and beliefs track perceived evidence, then moral peer disagreement would not be intelligible. Hence, moral judgments are not beliefs. The argument is both novel and interesting, but this paper argues that it fails to establish the conclusion. Beliefs are plausibly analyzed as constituted by dispositions to respond to what is perceived as evidence, but dispositions can always be interfered with. Provided a background explanation of why the disposition is not manifested, peer intransigence is quite intelligible.
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| 25. |
- Eriksson, John, 1973-
(författare)
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Moved by Morality : An Essay on the Practicality of Moral Thought and Talk
- 2006
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- It is part of our everyday experience that there is a reliable connection between moral opinions and motivation. Thinking that an act is right (wrong) tends to be accompanied by motivation to (avoid to) perform the act in question. This is mirrored in moral talk. We tend to think that someone who says that he thinks that it is right (wrong) to act in a certain way without being motivated, to some extent, will most likely be speaking insincerely. Moveover, moral utterances have a dynamic function to exhort and guide conduct. This suggests that moral utterances involve a kind of attitudinal expressiveness that makes them very different from prosaically factual utterances. These commonsensical features of our moral practice represent the practicality of moral thought and talk. The main purpose of this essay is to investigate how the practicality of moral thought and talk is best represented and whether it supports either a cognitivist or noncognitivist analysis of moral judgments. I argue that sophisticated versions of internalism and externalism, the main competing explanations of the connection between moral judgments and motivation, represent the reliable connection equally good and that the relevant kind of attitudinal expression can be accomodated by both cognitivists and noncognitivists. The upshot is that considerations based on the practicality of moral thought and talk does not cut much philosophical ice. Hence, the rivalry between cognitivists and noncognitivists analyses must be settled beyond considerations based on practicality. Maybe the belief-like features of moral thought and talk can tilt things in favor of cognitivism. However, noncognitivists have different ways of accommodating the belief-like features. In fact, in the wake of different accommodation projects one wonders what remains of the traditional debate between cognitivist and noncognitivist analyses, a debate that shaped metaethics as we know it.
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| 26. |
- Eriksson, John, 1973, et al.
(författare)
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Non-Cognitivism and the Classification Account of Moral Uncertainty
- 2016
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Ingår i: Australasian Journal of Philosophy. - : Informa UK Limited. - 0004-8402 .- 1471-6828. ; 94:4, s. 719-735
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Tidskriftsartikel (refereegranskat)abstract
- It has been objected to moral non-cognitivism that it cannot account for fundamental moral uncertainty. A person is derivatively uncertain about whether an act is, say, morally wrong, when her certainty is at bottom due to uncertainty about whether the act has certain non-moral, descriptive, properties, which she takes to be wrong-making. She is fundamentally morally uncertain when her uncertainty directly concerns whether the properties of the act are wrong-making. In this paper we advance a new reply to the objection to non-cognitivism, immune to the problems afflicting earlier replies. First, we argue that fundamental moral uncertainty is best understood as classificatory uncertainty, since (i) the psychological factors behind fundamental moral uncertainty are analogous to the factors behind fundamental uncertainty regarding descriptive, non-moral, matters, and (ii) fundamental descriptive uncertainty is naturally understood as classificatory uncertainty. We call this the classification account of moral uncertainty. Second, we argue that it is congenial with non-cognitivism, given certain plausible assumptions about the psychology of moral judgment formation.
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| 27. |
- Eriksson, John, 1973
(författare)
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Noncognitivism: From the Vienna Circle to the Present Day
- 2017
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Ingår i: The Cambridge History of Moral Philosophy / Edited by Sacha Golob and Jens Timmermann. - Cambridge : Cambridge University Press. - 9781107033054 ; , s. 591-606
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Bokkapitel (refereegranskat)
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| 28. |
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| 29. |
- Eriksson, John, 1973
(författare)
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Self-deception, agency and responsibility
- 2011
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Ingår i: 32nd International Congress on Law and Mental Health Berlin July 17th-23rd, 2011.
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Konferensbidrag (refereegranskat)
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| 30. |
- Eriksson, John, 1973
(författare)
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Self-expression, Expressiveness, and Sincerity
- 2010
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Ingår i: Acta Analytica. - : Springer Science and Business Media LLC. - 0353-5150 .- 1874-6349. ; 25:1, s. 71-79
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Tidskriftsartikel (refereegranskat)
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| 31. |
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| 32. |
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| 33. |
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| 34. |
- Fjendbo Petersen, Mette, et al.
(författare)
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Impacts by point and diffuse micropollutant sources on the stream water quality at catchment scale
- 2012
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Ingår i: Geophysical Research Abstracts. - Vienna : Copernicus Gesellschaft. ; , s. 11892-11892
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The water quality of surface waters is threatened by multiple anthropogenic pollutants and the large variety of pollutants challenges the monitoring and assessment of the water quality. The aim of this study was to characterize and quantify both point and diffuse sources of micropollutants impacting the water quality of a stream at catchment scale. Grindsted stream in western Jutland, Denmark was used as a study site. The stream passes both urban and agricultural areas and is impacted by severe groundwater contamination in Grindsted city. Along a 12 km reach of Grindsted stream, the potential pollution sources were identified including a pharmaceutical factory site with a contaminated old drainage ditch, two waste deposits, a wastewater treatment plant, overflow structures, fish farms, industrial discharges and diffuse agricultural and urban sources. Six water samples were collected along the stream and analyzed for general water quality parameters, inorganic constituents, pesticides, sulfonamides, chlorinated solvents, BTEXs, and paracetamol and ibuprofen. The latter two groups were not detected. The general water quality showed typical conditions for a stream in western Jutland. Minor impacts by releases of organic matter and nutrients were found after the fish farms and the waste water treatment plant. Nickel was found at concentrations 5.8 – 8.8 g/l. Nine pesticides and metabolites of both agricultural and urban use were detected along the stream; among these were the two most frequently detected and some rarely detected pesticides in Danish water courses. The concentrations were generally consistent with other findings in Danish streams and in the range 0.01 – 0.09 g/l; except for metribuzin-diketo that showed high concentrations up to 0.74 g/l. The groundwater contamination at the pharmaceutical factory site, the drainage ditch and the waste deposits is similar in composition containing among others sulfonamides and chlorinated solvents (including vinyl chloride). Vinyl chloride concentrations surpassed Danish stream water quality criteria with a factor 10. The largest chemical impact occurs at the reach downstream Grindsted city revealing that the main contaminant groundwater discharge zones are found here. The contaminant plume from the factory site north of the stream is known to impact the stream whereas the impact by the old landfill south of the stream remains to be assessed. A conceptual model of the chemical impacts by the identified sources was made, and high impact was assigned to the contaminant plume from the factory site and to the diffuse sources of urban-use and agricultural pesticides. The next step will be a quantification of the sources, which will be presented at the conference.
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| 35. |
- Lantero Rodriguez, Marta, et al.
(författare)
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Testosterone reduces metabolic brown fat activity in male mice
- 2021
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Ingår i: Journal of Endocrinology. - : Bioscientifica. - 0022-0795 .- 1479-6805. ; 251:1, s. 83-96
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Tidskriftsartikel (refereegranskat)abstract
- Brown adipose tissue (BAT) burns substantial amounts of mainly lipids to produce heat. Some studies indicate that BAT activity and core body temperature are lower in males than females. Here we investigated the role of testosterone and its receptor (the androgen receptor; AR) in metabolic BAT activity in male mice. Castration, which renders mice testosterone deficient, slightly promoted the expression of thermogenic markers in BAT, decreased BAT lipid content, and increased basal lipolysis in isolated brown adipocytes. Further, castration increased the core body temperature. Triglyceride-derived fatty acid uptake, a proxy for metabolic BAT activity in vivo, was strongly increased in BAT from castrated mice ( 4.5-fold increase vs sham-castrated mice) and testosterone replacement reversed the castration-induced increase in metabolic BAT activity. BAT-specific AR deficiency did not mimic the castration effects in vivo and AR agonist treatment did not diminish the activity of cultured brown adipocytes in vitro, suggesting that androgens do not modulate BAT activity via a direct, AR-mediated pathway. In conclusion, testosterone is a negative regulator of metabolic BAT activity in male mice. Our findings provide new insight into the metabolic actions of testosterone.
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| 36. |
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Motivational Internalism
- 2015
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- Motivational internalism—the thesis that there is an intrinsic or necessary connection between moral judgment and moral motivation—is a central thesis in a number of metaethical debates. In conjunction with a Humean picture of motivation, it has provided a challenge for cognitivist theories that take moral judgments to concern objective aspects of reality, and versions of internalism have been seen as having implications for moral absolutism, realism, non-naturalism, and rationalism. Being a constraint on theories of moral motivation and moral judgment, it is also directly relevant to wider issues in moral psychology. But internalism is a controversial thesis, and the apparent possibility of amoralists and the rejection of strong forms of internalism have also been seen as a problem for non-cognitivists. This volume is meant to help people appreciate the state of the art of research on internalism, to see connections between various aspects of the debate, and to deepen the discussion of a number of central aspects. The introductory chapter provides a structured overview of the debate with a focus on the last two decades or so, distinguishing several important threads and trends in recent developments. The 13 chapters of original research are divided into three parts. The essays in the first part focus on what evidence there is for or against various versions of internalism, those in the second on the relevance of versions of internalism for wider metaethical issues, and those in the third develop different ways of accommodating both internalist and externalist aspects of moral practice.
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| 37. |
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