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Sökning: WFRF:(Eriksson Malin 1969 )

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1.
  • Drevinge, Christina, 1983, et al. (författare)
  • Perilipin 5 is protective in the ischemic heart
  • 2016
  • Ingår i: International Journal of Cardiology. - : Elsevier BV. - 0167-5273 .- 1874-1754. ; 219, s. 446-454
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Myocardial ischemia is associated with alterations in cardiac metabolism, resulting in decreased fatty acid oxidation and increased lipid accumulation. Here we investigate how myocardial lipid content and dynamics affect the function of the ischemic heart, and focus on the role of the lipid droplet protein perilipin 5 (Plin5) in the pathophysiology of myocardial ischemia. Methods and results: We generated Plin5(-/-) mice and found that Plin5 deficiency dramatically reduced the triglyceride content in the heart. Under normal conditions, Plin5(-/-) mice maintained a close to normal heart function by decreasing fatty acid uptake and increasing glucose uptake, thus preserving the energy balance. However, during stress or myocardial ischemia, Plin5 deficiency resulted in myocardial reduced substrate availability, severely reduced heart function and increased mortality. Importantly, analysis of a human cohort with suspected coronary artery disease showed that a common noncoding polymorphism, rs884164, decreases the cardiac expression of PLIN5 and is associated with reduced heart function following myocardial ischemia, indicating a role for Plin5 in cardiac dysfunction. Conclusion: Our findings indicate that Plin5 deficiency alters cardiac lipid metabolism and associates with reduced survival following myocardial ischemia, suggesting that Plin5 plays a beneficial role in the heart following ischemia. (C) 2016 The Authors. Published by Elsevier Ireland Ltd.
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3.
  • Eklund Wimelius, Malin, 1972-, et al. (författare)
  • "They think of us as part of the problem instead of part of the solution" : Swedish civil society and faith based organizations in resilience building and prevention of radicalization and violent Islamist extremism
  • 2020
  • Ingår i: Journal for Deradicalization. - : German Institute on Radicalization and De-Radicalization Studies (GIRDS). - 2363-9849. ; :22, s. 122-154
  • Tidskriftsartikel (refereegranskat)abstract
    • Radicalization and violent extremism are pressing issues on the Swedish political agenda. The local level has been identified as pivotal when it comes to preventive work and local public actors are encouraged to cooperate with civil society in efforts to promote local resilience. However, the Swedish debate on the role of civil society organizations (CSOs) and faith based organizations (FBOs) in resilience building and prevention is heated. Based on 14 interviews with representatives for secular, Christian and Muslim CSOs and FBOs, we have explored and analysed how they perceive their role in resilience building and preventive work. We have asked how they interpret local resilience against radicalization and violent extremism and what they think is needed in order to promote it. Findings are mirrored against a recent literature review on local resilience. In the interviews, there is a strong emphasis on work to strengthen social support networks, enhance community resources and build collective identity. In relation to the literature review, there are significant similarities with how resilience is defined and said to be promoted.
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4.
  • Eriksson, Malin, 1969-, et al. (författare)
  • Ensamkommande ungdomars placering vid SiS särskilda ungdomshem : Placeringsmotiv, problembild och insatser
  • 2021
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Under år 2017 var nästan 33 procent av samtliga pojkar placerade på SiS, ensamkommande ungdomar. För SiS innebär gruppen ensamkommande ungdomar nya utmaningar genom språkbarriärer och komplex  problematik.Syftet med rapporten är att bidra till ökad kunskap om på vilka grunder ensamkommande ungdomar placeras på SiS, hur placeringsinsatsen organiseras och om insatserna under placeringen skiljer sig jämfört med insatserna för andra placerade ungdomar. Rapporten fokuserar på följande forskningsfrågor: Vilka motiv ligger till grund för ensamkommande ungdomars placering på SiS? Vilka problem avser en SiS-placering lösa? Finns det skillnader mellan hur olika aktörer uppfattar motiv och problem vid SiS-placering? Vilka insatser genomförs under placeringstiden och hur uppfattas dessa? Skiljer sig användningen av särskilda befogenheter i hanteringen av ensamkommande ungdomar jämfört med andra placerade ungdomar?Svaren på forskningsfrågorna baseras på intervjuer med SiS-personal, socialsekreterare och ensamkommande ungdomar placerade vid SiS, avidentifierade journaler samt data ur klient- och institutionsadministrativa system (KIA).Resultaten visar att två övergripande och delvis motstridiga bilder framträder vad gäller motiv för placering av ensamkommande ungdomar på SiS. Å ena sidan finns uppfattningen att ensamkommande ungdomar har en komplex problematik vilket motiverar placering på SiS. Å andra sidan uppfattas en del av de ensamkommande på SiS som felplacerade eller placerade på för vaga grunder. De insatser som ges under placeringen handlar till stor del om att ge struktur, fasta ramar och upprätta en vardag, vilket SiS har goda förutsättningar att lyckas med inom ramen för den strukturerade tvångsvårdsmiljö som erbjuds. Insatser som avser att hjälpa ensamkommande ungdomar att ”uppnå drogfrihet” eller ”komma ifrån en kriminell livsstil” har dock sämre förutsättningar att lyckas inom SiS, då dessa insatser utformas med det svenska språket och ”svenska bärande samhällsnormer” som grund. När det gäller användandet av särskilda befogenheter, visar resultaten att dessa används i lägre utsträckning för ensamkommande jämfört med andra ungdomar.
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5.
  • Ghazinour, Mehdi, 1967-, et al. (författare)
  • Are the problems and motives clear enough? : A study on the placement of unaccompanied asylum-seeking minors at compulsory care institutions in Sweden
  • 2021
  • Ingår i: The Journal of Refugee Studies. - : Oxford University Press. - 0951-6328 .- 1471-6925. ; 34:2, s. 1675-1694
  • Tidskriftsartikel (refereegranskat)abstract
    • The Swedish National Board of Institutional Care (SNBIC) is an independent governmental agency that provides compulsory care for minors with psychosocial problems, criminal behavior, and substance abuse. During recent years, a noticeable number of the youth placed at compulsory care institutions have been asylum-seeking minors who have arrived in Sweden without parents or guardians. This steady increase in placements has raised questions and concerns among the involved actors regarding the motives and needs underlying these placements. This qualitative study investigates the main motives that lead unaccompanied asylum-seeking minors to be placed at SNBIC residential homes and the problems that are to be solved during their placement, according to social workers and SNBIC staff. The study is based on 28 in-depth interviews with social workers and SNBIC staff. Findings indicate clear disagreement between social workers and SNBIC staff with regard to the motives for placing unaccompanied minors at SNBIC homes. Although the social workers and SNBIC staff explain that most of the unaccompanied youth placed at SNBIC homes have some form of criminal behavior or substance abuse, SNBIC staff believe, in some cases, the problem is not sufficiently serious to warrant compulsory care. As these disagreements and misunderstandings between the actors have an impact on their collaboration and, consequently, the situation of the unaccompanied minors, all attempts to reach a consensus on the leading causes for placement and the problems that need to be solved with SNBIC placement would increase security for both the young people and the relevant staff.
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6.
  • Ghazinour, Mehdi, 1967-, et al. (författare)
  • Ensamkommande barns placering vid SiS särskilda ungdomshem : Vilka place­ras, hur mår de och vilka insatser får de?
  • 2019
  • Ingår i: Socialmedicinsk Tidskrift. - Stockholm : Socialmedicinsk tidskrift. - 0037-833X. ; 96:1, s. 22-37
  • Tidskriftsartikel (refereegranskat)abstract
    • Antalet asylsökande barn har globalt ökat dramatiskt de senaste åren och Sverige har under flera år mottagit ensamkommande ungdomar. Deras behov har tillgodosetts genom samarbete mellan ett stort antal aktörer. De senaste åren har antalet ensamkommande ungdomar som placerats för tvångsvård vid SiS särskilda ungdomshem ökat. Syftet med denna artikel är att beskriva vad som kännetecknar ensamkommande ungdomar som placeras på SiS särskilda ungdomshem, beträffande bakgrund, asylstatus, hälsa och tillgång till sociala nätverk samt att beskriva de insatser som genomförs vid placering av ensamkommande ungdomar på SiS. Resultaten baseras på en genom-gång av avidentifierade journaler från 25 ensamkommande ungdomar som varit placerade på SiS under 2015, och visar att gruppen som sådan består av en majoritet pojkar, flertalet har traumatiska upplevelser i sitt förflutna, en majoritet har en dokumenterad psykisk ohälsa, tillgången till sociala nätverk i Sverige är begränsad och flertalet saknar uppehållstillstånd i Sverige.
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7.
  • Klevstig, Martina, et al. (författare)
  • Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia
  • 2019
  • Ingår i: Journal of Molecular and Cellular Cardiology. - : Elsevier BV. - 0022-2828 .- 1095-8584. ; 137, s. 1-8
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: The microsomal triglyceride transport protein (MTTP) is critical for assembly and secretion of apolipoprotein B (apoB)-containing lipoproteins and is most abundant in the liver and intestine. Surprisingly, MTTP is also expressed in the heart. Here we tested the functional relevance of cardiac MTTP expression. Materials and methods: We combined clinical studies, advanced expression analysis of human heart biopsies and analyses in genetically modified mice lacking cardiac expression of the MTTP-A isoform of MTTP. Results: Our results indicate that lower cardiac MTTP expression in humans is associated with structural and perfusion abnormalities in patients with ischemic heart disease. MTTP-A deficiency in mice heart does not affect total MTTP expression, activity or lipid concentration in the heart. Despite this, MTTP-A deficient mice displayed impaired cardiac function after a myocardial infarction. Expression analysis of MTTP indicates that MTTP expression is linked to cardiac function and responses in the heart. Conclusions: Our results indicate that MTTP may play an important role for the heart function in conjunction to ischemic events.
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8.
  • Strandh, Veronica, 1982-, et al. (författare)
  • Allmänhetens kännedom om våldsbejakandeextremism och om kommunernas arbete
  • 2018
  • Ingår i: Mänsklig säkerhet.
  • Tidskriftsartikel (populärvet., debatt m.m.)abstract
    • Kommunernas roll i det förebyggande arbetet mot våldsbejakande extremism framhålls ofta som central. Kraven och förväntningarna på kommunerna har  ökat och många har idag inte bara lokala samordnare mot våldsbejakande extremism, utan också egna handlingsplaner. Kunskap och forskning om hur kommunerna arbetar har dessutom vuxit. Hur allmänheten ser på kommunernas arbete och på våldsbejakande extremism som fenomen vet vi emellertid mindre om. I den här artikeln redovisas en delmängd från en nationell enkätundersökning som ingår i ett forskningsprojekt vid Umeå universitet om radikalisering och lokal motståndskraft. Resultat från enkätundersökningen visar bland annat att våldsbejakande extremism oroar allmänheten men att få vet till vem man på lokal nivå skall vända sig med frågor som rör detta och att förtroendet för kommunernas arbete är relativt lågt.
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9.
  • Ahlborg, Mikael G., et al. (författare)
  • SoCap YMH - youth mental health, social capital and help-seeking : a study protocol
  • 2024
  • Ingår i: Frontiers in Public Health. - : Frontiers Media S.A.. - 2296-2565. ; 12
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The increase in adolescents reporting mental health problems presents a major public health challenge. The complex association between mental health and social capital motivates further investigation of social capital as a crucial aspect in shaping adolescents' help-seeking knowledge, attitudes, and behaviours.Aim: This protocol presents a project that aims to investigate social capital in relation to help-seeking and mental health in close collaboration with adolescents and key stakeholders in the school setting, in the southern part of Sweden.Methods: A mixed-method design with three interconnected work packages (WP) will be undertaken with an emphasis on co-production where adolescents are involved throughout the process. WP1 is a development and validation of two questionnaire instruments for assessing social capital and help-seeking in adolescence. WP2 is a longitudinal quantitative study involving 1,500 adolescents from two regions representing rural and suburban/urban settings. Adolescents aged 15 will be asked to complete questionnaires concerning social capital, mental health, and help-seeking in a baseline and one-year follow-up, allowing for investigation of the role of social capital for help-seeking. WP3 is designed to elucidate experiences and knowledge of adolescents and key stakeholders via collaborative World Café workshops. These will be held along the project to evolve the generated knowledge and maximize it's applicability during and after the project is finalized.Conclusion: The results are expected to further the understanding of the relationship between adolescents' social capital, mental health, and help-seeking, to contribute to a deeper understanding of the mechanisms behind the paradoxical help-seeking patterns among adolescents today and to narrow the gap between research and practice to produce sustainable and efficient strategies, which may facilitate help-seeking and improve the mental health of adolescents within existing organizational structures.
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10.
  • Ahlborg, Mikael, 1985-, et al. (författare)
  • SoCap YMH - youth mental health, social capital and help-seeking : a study protocol
  • 2024
  • Ingår i: Frontiers in Public Health. - Lausanne : Frontiers Media S.A.. - 2296-2565. ; 12
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The increase in adolescents reporting mental health problems presents a major public health challenge. The complex association between mental health and social capital motivates further investigation of social capital as a crucial aspect in shaping adolescents' help-seeking knowledge, attitudes, and behaviours. Aim: This protocol presents a project that aims to investigate social capital in relation to help-seeking and mental health in close collaboration with adolescents and key stakeholders in the school setting, in the southern part of Sweden. Methods: A mixed-method design with three interconnected work packages (WP) will be undertaken with an emphasis on co-production where adolescents are involved throughout the process. WP1 is a development and validation of two questionnaire instruments for assessing social capital and help-seeking in adolescence. WP2 is a longitudinal quantitative study involving 1,500 adolescents from two regions representing rural and suburban/urban settings. Adolescents aged 15 will be asked to complete questionnaires concerning social capital, mental health, and help-seeking in a baseline and one-year follow-up, allowing for investigation of the role of social capital for help-seeking. WP3 is designed to elucidate experiences and knowledge of adolescents and key stakeholders via collaborative World Café workshops. These will be held along the project to evolve the generated knowledge and maximize it's applicability during and after the project is finalized. Conclusion: The results are expected to further the understanding of the relationship between adolescents' social capital, mental health, and help-seeking, to contribute to a deeper understanding of the mechanisms behind the paradoxical help-seeking patterns among adolescents today and to narrow the gap between research and practice to produce sustainable and efficient strategies, which may facilitate help-seeking and improve the mental health of adolescents within existing organizational structures. Copyright © 2024 Ahlborg, Morgan, Svedberg, Nygren, Eriksson and Westberg.
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11.
  • Ander, Magnus, et al. (författare)
  • Elchockvapen som hjälpmedel vid polisiära ingripanden : En vetenskaplig utvärdering av Polismyndighetens försöksverksamhet med elchockvapen 2018-2019
  • 2020
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • BAKGRUND: Ur ett internationellt perspektiv har det, inom polisen, under de senaste åren skett en ökning i använ­dandet av mindre dödliga vapen. Dessa vapen används för att ta kontroll över potentiellt farliga och icke samarbetsvilliga personer. Ett vanligt förekommande mindre dödligt vapen är elchockvapen (ECV). Elchockvapen har fram till 2018 inte använts i Sverige, men Polismyndigheten har under åren 2018–2019 genomfört en försöksverksamhet med ECV.SYFTE: Syftet med undersökningen var att utvärdera Polismyndighetens försöksverksamhet med ECV, samt att undersöka vilken legitimitet polisens användning av ECV har bland allmänheten.METOD: Både kvantitativa och kvalitativa data samlades in för att utvärdera försöket med ECV. Mätningar före, under, och i slutet av försöksverksamheten genomfördes med hjälp av en enkät. Enkäten besvarades av två grupper av poliser; en grupp som ingick i försöksverksamheten med ECV samt en kontrollgrupp poliser som inte ingick i försöksverksamheten. För att fördjupa förståelsen för enkätresultaten genom­fördes djupintervjuer och fokusgruppsintervjuer med poliser som hade erfarenhet av ECV under för­söksverksamheten. För att undersöka legitimitetsaspekter utifrån ett medborgarperspektiv genomför­des fokusgrupper med deltagare från allmänheten. Data från Polisens arbetsskadesystem LISA inhämtades för att undersöka ECV:s inverkan på skador hos poliserna.RESULTAT: Enkätresultaten visade inga skillnader mellan delaktiga och kontrollgrupp när det gäller upplevelse av stressfulla situationer. Upplevelsen av trygghet vid ingripanden med hög grad av motstånd eller när polisen blir fysisk angripen har dock ökat för de poliser som deltagit i ECV­försöket, jämfört med kon­trollgruppen. Intervjuresultaten åskådliggör också att tillgången till ECV bidrar till att minska upplevel­sen av stress i våldsamma situationer genom att ECV ökar tryggheten i sådana situationer. Intervjure­sultaten påvisar även att tillgången till ECV gör att man slipper använda andra potentiellt skadligare våldshjälpmedel såsom fysiska metoder och skjutvapen. Enkätresultatet visar ingen skillnad mellan de som ingick i försöksverksamheten och kontrollgruppen när det gäller att utsättas för hot, våld eller motstånd, eller att polis eller motpart blir skadade. Resultaten från intervjuer och fokusgrupper syn­liggör att poliserna upplever att ECV fyller en viktig funktion. Poliserna ser enbart fördelar med ECV och vissa menar att det är det bästa verktyg som de har fått. ECV upplevs kunna rädda liv, minska skad­or på polis och motpart, samt förbättra arbetsmiljön för poliser. Intervjuer och fokusgrupper pekar på att deltagarna upplever att ECV har en de­eskalerande inverkan, vilket både kan minska våldsanvänd­ningen, och förebygga våld mot polisen. Enkät­ och intervjuresultaten indikerar att ECV bidrar till en minskad användning av andra hjälpmedel såsom batong och pepparspray, vilka ofta ger mer skador på både motpart och polis. Deltagarna från allmänheten har uppfattningen att ECV är ett effektivt och bra verktyg för polisen, men lyfter vikten av att det finns en lyhördhet gällande vilka situationer som den används i och mot vem.SLUTSATSER: Utifrån våra enkätresultat är det svårt att dra några säkra slutsatser kring hur användandet av ECV in­verkar på skador hos poliser och motpart. Erfarenheterna bland de delaktiga är dock att risken för våld och skador minskar markant, vilket är en viktig indikator. Tillgången till ECV kan öka trygghet och minska stress i ingripandesituationer där kraftigt motstånd och våld förekommer. ECV kan även mins­ka användandet av pepparspray och batong, och det finns indikationer på att ECV har använts istället för skjutvapen. ECV kan underlätta val av hjälpmedel vid ingripanden med hög grad av hot och våld och kan ha en de­eskalerande inverkan. Polisens användande av våldshjälpmedel, inklusive ECV, upp­levs berättigat av informanterna från allmänheten. 
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12.
  • Blom, Björn, 1965-, et al. (författare)
  • Socialtjänstens arbete med social hållbarhet : en introduktion
  • 2023
  • Ingår i: Socialtjänstens arbete med social hållbarhet. - Lund : Studentlitteratur AB. - 9789144153162 ; , s. 21-37
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • Den här antologin handlar om socialtjänstens arbete med social hållbarhet. Det är ett tema som per definition kan sägas vara betydelsefullt, men samtidigt är det oklart vad det innebär, både i teori och praktik. Vi förmodar att olika läsare närmar sig boken med skilda förväntningar och förkunskaper. Några frågor som antagligen kan infinna sig är: Vad är social hållbarhet? Vad finns det för koppling mellan social hållbarhet och socialtjänstens arbete? Är socialtjänstens arbete med social hållbarhet något nytt? Vilka behöver kunskap om socialtjänstens arbete med social hållbarhet och varför? I det här kapitlet för vi en introducerade diskussion i anslutning till dessa frågor. Därigenom läggs en grund för bokens övriga kapitel där olika aspekter av socialtjänstens arbete med social hållbarhet behandlas mer ingående.
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13.
  • Briones-Vozmediano, E., et al. (författare)
  • Young men's discourses of health service utilization for Chlamydia infection testing in Stockholm
  • 2020
  • Ingår i: European Journal of Public Health. - : Oxford University Press. - 1101-1262 .- 1464-360X. ; 30:Issue Supplement_5
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Background:Chlamydia Trachomatis (CT) infection is the most commonly reported sexually transmitted bacterial disease in Sweden, other European countries, as well as globally. CT is often asymptomatic and if it goes untreated it can cause severe reproductive health issues. In Sweden, men test for CT in a much lesser extent than women. The aim of this study is to identify factors influencing Swedish young men to use Health care for CT detection.Methods:Qualitative study based on 18 semi-structured interviews with young men (18-30 years old) in Stockholm during 2018. A Situational Analysis was conducted (a development of Constructivist Grounded Theory) of the interviews' transcriptions, using Open Code as the software for qualitative analysis in order to code and organize the information obtained. We constructed a situational map to illustrate the positions taken by Swedish young men according to their discourses.Results:Three ideal types of Swedish young men with different discourses and behaviors towards CT testing were identified: unconcerned men are indifferent about CT and other sexual transmitted infections (STI) and therefore not testing; ambivalent men only test when suspect suffering from an STI and/or are influenced by their social network; Whereas, proactive men test regularly as a way to know they are healthy. The differences between the ideal types are explained by their risk perception, the role of health services, and the positive or negative influence of their social network.Conclusions:The ideal types of young men identified in this study show a range of discourses linked to their risk perception, the role of health services, and the influence of their social network, which in practice is translated into different behaviours adopted for CT testing. Testing should be encouraged as an important part of CT prevention by educating groups of unconcerned young men about both the consequences of untreated CT and the free testing options available in Sweden.Key messages: Swedish young men have different discourses towards CT testing depending on their risk perception, the strategies adopted to test and the positive or negative role of their social network.The role of health services and the social support emerged as key factors to promoting testing among Swedish Young men.
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14.
  • Canabarro, Ana Paula Finatto, et al. (författare)
  • Cognitive social capital as a health-enabling factor for STI testing among young men in Stockholm, Sweden : A cross-sectional population-based study
  • 2023
  • Ingår i: Heliyon. - : Elsevier. - 2405-8440. ; 9:10
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To assess whether different forms of cognitive social capital increased the relative probability of testing for sexually transmitted infections (STIs) among young men living in Stockholm, Sweden.Methods: A population-based cross-sectional study was conducted in 2017 with men aged 20–29 years living in Stockholm County, Sweden (n = 523). The main outcome was STI testing patterns (never tested, tested only within a 12-month period, tested only beyond a 12-month period, repeatedly tested). The main exposure were two forms of cognitive social capital: social support (having received help, having someone to share inner feelings with) and institutionalized trust (in school, healthcare, media). Data were analyzed using weighted multivariable multinomial logistic regression to obtain adjusted weighted relative probability ratio (aRPR).Results: After adjusting for confounding factors, receiving help (aRPR: 5.2, 95% CI: 1.7–16.2) and having someone to share inner feelings with (aRPR: 3.1, 95% CI: 1.2–7.7) increased the relative probabilities of young men testing for STIs, but only for those testing beyond a 12-month period. Trust in media increased the relative probability of STI testing for those testing only within a 12-month period (aRPR: 2.6, 95% CI: 1.1–6.1) and for those testing repeatedly (aRPR: 3.6, 95% CI: 1.5–8.8).Conclusion: Young men in Stockholm County exhibit distinct STI testing patterns. Social support and trust in media were factors that increased the probability of being tested for STIs, with this effect varying according to the young men's STI testing pattern. Further studies are required to explore how trust in media might promote STI testing in this population.
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17.
  • Eriksson, Malin, 1969-, et al. (författare)
  • Children's perspectives on health promoting living environmens: the significance of social capital
  • 2020
  • Ingår i: Social Science and Medicine. - : Elsevier. - 0277-9536 .- 1873-5347. ; 258
  • Tidskriftsartikel (refereegranskat)abstract
    • This article discusses the usefulness of social capital as a conceptual tool to design neighbourhoods promoting children’s health. The aim was to explore children’s perspectives of health promoting environments, and we used a combination of photovoice and grounded theory. Children from two neighbourhoods in a Swedish municipality were invited to photograph and discuss places of importance for their well-being. They presented places facilitating togetherness, enjoyable activities and positive emotions, mostly found in their immediate environments: at home, at school and in their neighbourhoods, but the access to these places was unequally distributed between the areas. The results highlight a need for ensuring all children’s access to health promoting places and to include children’s views in policy and planning. Investments in the physical environment need to be combined with efforts to influence norms and collective efficacy to secure local ownership and use of these investments. We found that the concept of social capital is a relevant conceptual tool for understanding what constitutes health-promoting places from children’s perspectives and contributes to a deeper understanding on how physical and social environments are interlinked.
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19.
  • Eriksson, Malin, 1969- (författare)
  • En essä om sociala bestämningsfaktorer för hälsan som ett användbart begreppsligt ramverk för hälso- och sjukvårdskuratorernas arbete
  • 2022
  • Ingår i: Socionomens forskningssupplement. - : Akademikerförbundet SSR. - 0283-1929. ; :52
  • Tidskriftsartikel (refereegranskat)abstract
    • Kunskapen om sambanden mellan sociala livsvillkor och hälsa var tidigt en central utgångspunkt för hälso- och sjukvårdskuratorernas arbete, men har över tid tenderat att underordnas ett fokus på mer individinriktade insatser. Samtidigt beskrivs ofta hälso- och sjukvårdskuratorerna ha en otydlig yrkesroll och en svag professionell ställning. Den nya legitimationsgrundande examen utgör en unik möjlighet att förtydliga hälso- och sjukvårdskuratorernas yrkesroll, och kan idealt leda till utvecklandet av ett samlat begreppsligt ramverk för arbetet. I denna essä lyfter jag ramverket om de sociala bestämningsfaktorerna för hälsan som ett lämpligt begreppsligt ramverk för hälso- och sjukvårdskuratorernas arbete. Ramverket passar väl in i kuratorernas generalistexpertis och biopsykosociala perspektiv, och skulle kunna bidra till att tydliggöra yrkesgruppens unika kompetens. Ramverket om de sociala bestämningsfaktorerna för hälsan kan också användas för att återaktualisera och tydliggöra behovet av kurativa insatser inte bara på individ- utan även på meso- och makronivå.
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20.
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21.
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22.
  • Eriksson, Malin, 1969-, et al. (författare)
  • Social Capital and Sustainable Social Development-How Are Changes in Neighbourhood Social Capital Associated with Neighbourhood Sociodemographic and Socioeconomic Characteristics?
  • 2021
  • Ingår i: Sustainability. - : MDPI AG. - 2071-1050. ; 13:23
  • Tidskriftsartikel (refereegranskat)abstract
    • The development of social capital is acknowledged as key for sustainable social development. Little is known about how social capital changes over time and how it correlates with sociodemographic and socioeconomic factors. This study was conducted in 46 neighbourhoods in Umea Municipality, northern Sweden. The aim was to examine neighbourhood-level characteristics associated with changes in neighbourhood social capital and to discuss implications for local policies for sustainable social development. We designed an ecological study linking survey data to registry data in 2006 and 2020. Over 14 years, social capital increased in 9 and decreased in 15 neighbourhoods. Higher levels of social capital were associated with specific sociodemographic factors, but these differed in urban and rural areas. Urban neighbourhoods with a higher proportion of older pensioners (OR = 1.49, CI: 1.16-1.92), children under 12 (OR= 2.13, CI: 1.31-3.47), or a lower proportion of foreign-born members (OR= 0.32, CI: 0.19-0.55) had higher odds for higher social capital levels. In rural neighbourhoods, a higher proportion of single-parent households was associated with higher levels of social capital (OR = 1.44, 95% CI = 1.04-1.98). Neighbourhood socioeconomic factors such as income or educational level did not influence neighbourhood social capital. Using repeated measures of social capital, this study gives insights into how social capital changes over time in local areas and the factors influencing its development. Local policies to promote social capital for sustainable social development should strive to integrate diverse demographic groups within neighbourhoods and should increase opportunities for inter-ethnic interactions.
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23.
  • Eriksson, Malin, 1969-, et al. (författare)
  • Social capital, gender and educational level : impact on self-rated health
  • 2010
  • Ingår i: The Open Public Health Journal. - : Bentham Science Publishers. - 1874-9445. ; 3, s. 1-12
  • Tidskriftsartikel (refereegranskat)abstract
    • Objectives: Social capital has been recognized as one important social determinant for health, but we still have limited knowledge about how it can be used to explain inequality in health. This study investigated the links between individual social capital and self-rated health by gender and educational level, and analyzed if access to social capital might explain the observed disparities in self-rated health between men and women and different educational groups. Study design: A cross-sectional survey in Northern Sweden. Methods: A social capital questionnaire was constructed and mailed to 15 000 randomly selected individuals. Different forms of structural and cognitive social capital were measured. Self-rated health was used as the outcome measure. Crude and adjusted OR and 95% CI were calculated for good selfrated health and access to each form of social capital. Multivariate regression was used to analyze how sociodemographic factors and access to social capital might influence differences in self-rated health by gender and educational level. Results: Access to almost each form of social capital significantly increased the odds for good self-rated health for all groups. A higher education significantly increased the odds for access to each form of social capital, and being a man significantly increased the odds for having access to some forms of social capital. The health advantage for higher educated and men partly decreased when controlling for access to social capital. Conclusions: Access to social capital can partly explain the observed health inequality between men and women and different educational groups. Strengthening social capital might be one way of tackling health inequality. It is important to consider the structural conditions that create unequal opportunities for different groups to access social capital.
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24.
  • Eriksson, Malin, 1969- (författare)
  • Social capital, health and community action : implications for health promotion
  • 2010
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background; The overwhelming increase in studies about social capital and health occurring since 1995 indicates a renewed interest in the social determinants of health and a call for a more explicit use of theory in public health and epidemiology. The links between social capital and health are still not clear and the meanings of different forms of individual and collective social capital and their implications for health promotion needs further exploration. The overall aims of this thesis are to explore the relationship between social capital and health and to contribute to the theoretical framework of the role of social capital for health and health promotion.Methods; Data from a social capital survey were used to investigate the associations between individual social capital and self-rated health for men and women and different educational groups. Survey data were also analyzed to determine the association between collective social capital and self-rated health for men and women. A qualitative case study in a small community with observed high levels of civic engagement formed the basis for exploring the role of social capital for community action. Data from the same study were utilized for a grounded theory situational analysis of the social mechanisms leading to social capital mobilization.Main findings; Access to individual social capital increases the odds for good self-rated health equally for men and women and different educational groups. However, the likelihood of having access to social capital differs between groups. The results indicate a positive association between collective social capital and self-rated health for women but not for men. Results from the qualitative case study illustrate how social capital in local communities can facilitate collective actions for public good but may also increase social inequality. Mobilizing social capital in local communities requires identification of community issues that call for action, a fighting spirit from trusted local leaders, “know-how” from creative entrepreneurs, and broad legitimacy and support in the community.Conclusions; This thesis supports the idea that individual social capital is health-enhancing and that strengthening individual social capital can be considered one important health promotion strategy. Collective social capital may have a positive effect on self-rated health for women but not for men and therefore mobilizing collective social capital might be more health-enhancing for women. Collective social capital may have indirect positive effects on health for all by facilitating the ability of communities to solve collective health problems. However, mobilizing social capital in local communities requires an awareness of the risk for increased social inequality.
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25.
  • Eriksson, Malin, 1969- (författare)
  • Socialt kapital och lokalt polisarbete
  • 2022. - 1
  • Ingår i: Polisiärt arbete i utsatta områden. - Lund : Studentlitteratur AB. - 9789144140957 ; , s. 225-245
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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26.
  • Eriksson, Malin, 1969- (författare)
  • Twenty years of research on social capital and health : what is the utility for health promotion?
  • 2020
  • Ingår i: Socialmedicinsk Tidskrift. - Stockholm : Stiftelsen Socialmedicinsk tidskrift. - 0037-833X. ; 97:3, s. 467-477
  • Tidskriftsartikel (refereegranskat)abstract
    • Despite the huge amount of research about social capital and health during the last 20 years, the utility of this knowledge for health promotion remains unclear. This article aims to conceptualise social capital in relation to health promotion and to identify what is required for social capital to be used as a resource in health promotion. It suggests that social capital has become an important concept in health promotion but that many challenges remain on how it could be utilised in policy and practice. Social capital does not add any ground-breaking new knowledge in health promotion but complements already existing knowledge within social networks/social support and community development approaches in health promotion. Utilizing social capital in health promotion requires an awareness of power relations and social inequality, as well as the political structures that exist were the intervention take place. There is a need for more systematic explorations of case studies attempting to utilise social capital in health promotion.
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27.
  • Eriksson, Malin, 1969-, et al. (författare)
  • Understanding the role of social capital for health promotion beyond Putnam : a qualitative case study from northern Sweden
  • 2009
  • Ingår i: Social theory and health. - : Springer Science and Business Media LLC. - 1477-8211 .- 1477-822X. ; 7:4, s. 318-338
  • Tidskriftsartikel (refereegranskat)abstract
    • Social capital is believed to improve the capacity of communities to work together for solving collective health problems. The present study was conducted in a community in northern Sweden where citizens through collective actions managed to build an association-driven health center. The aims were to describe the community's existing social capital in order to explore how Putnam's theories could contribute to an understanding of the observed high civic engagement and to discuss how other theoretical perspectives might add to an understanding of the role of social capital for health promotion. A qualitative case study was performed and the analysis followed a grounded theory approach. In accordance with Putnam, inherited social capital and high participation in existing associations were found to be important for uniting people. Beyond these, other aspects such as effective information channels, strong leaders and high social control were also significant and better understood by adding Coleman's and Bourdieu's views of social capital. If social capital is to be used for the purposes of health promotion the risk of increased social inequality as an unintended consequence needs to be considered. An awareness of how specific contextual conditions affect the building and mobilizing of social capital is also crucial.
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28.
  • Erlandsson, Malin, 1972, et al. (författare)
  • Survivin improves the early recognition of rheumatoid arthritis among patients with arthralgia : A population-based study within two university cities of Sweden
  • 2018
  • Ingår i: Seminars in Arthritis & Rheumatism. - : Saunders Elsevier. - 0049-0172 .- 1532-866X. ; 47:6, s. 778-785
  • Forskningsöversikt (refereegranskat)abstract
    • Objectives: The aim of this study was to validate the use of survivin for preclinical recognition of rheumatoid arthritis (RA) among patients with unexplained arthralgia.Methods: Serum levels of survivin and the arthritis-specific autoantibodies RF and ACPA were measured in total of 5046 patients with musculoskeletal complains during 12 consecutive months in Gothenburg and in Umea. Among them, 303 arthralgia patients were identified and prospectively followed.Results: After 48 months, 12.2% of the arthralgia patients developed RA. Most of RA cases had high serum survivin, which increased the relative risk for RA (RR = 5.90,p = 3 x 10(-7)). Combination of survivin with autoantibodies was present in only 4.6% of the arthralgia patients and increased further the risk of RA and shortened time to RA development. Presence of any single autoantibody in the survivin-negative patients was associated with a minor risk for RA and had RA-free survival similar to the reference group.Conclusion: This study shows that measurement of survivin in serum improves estimation of RA risk and prospectively predicts RA development in patients with arthralgia. Survivin may indicate a phase preceding autoantibody production. 
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29.
  • Ghazinour, Mehdi, 1967-, et al. (författare)
  • Den psykiska hälsan hos poliser som arbetar i yttre tjänst i särskilt utsatta områden
  • 2021
  • Ingår i: Socialmedicinsk Tidskrift. - : Stiftelsen Socialmedicinsk tidskrift. - 0037-833X. ; 98:2, s. 290-302
  • Tidskriftsartikel (refereegranskat)abstract
    • Artikelns syfte är att belysa den psykiska hälsan hos svenska poliser som arbetar i yttre tjänst. Polisernas psykiska hälsa är ett viktigt forskningsområde med tanke på hur polisen arbetar i samhället. Att utföra enkla och svåra arbetsuppgifter ställer höga krav på polisens mentala processer. I den här artikeln uppmärksammar vi poliser i yttre tjänst som arbetar i särskilt utsatta områden i Stockholmregionen. Det självskattade frågeformuläret DSM-5 om psykisk hälsa har insamlats och analyserats med hjälp av beskrivande statistik. Resultatet visar att stigande ålder och att leva i en parrelation är skyddsfaktorer mot psykisk ohälsa hos dessa poliser.
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30.
  • Ghazinour, Mehdi, 1967-, et al. (författare)
  • Inledning
  • 2022. - 1
  • Ingår i: Polisiärt arbete i utsatta områden. - Lund : Studentlitteratur AB. - 9789144140957 ; , s. 17-21
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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31.
  • Ghazinour, Mehdi, 1967-, et al. (författare)
  • Inledning
  • 2022
  • Ingår i: Polisiärt arbete i utsatta områden. - Lund : Studentlitteratur AB. - 9789144140957 ; , s. 17-21
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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32.
  • Hallander, Per, 1970-, et al. (författare)
  • Using tailored temperature variations to obtain flawless forming of multi-stacked unidirectional prepreg
  • 2020
  • Ingår i: Journal of composite materials. - : SAGE Publications Ltd. - 0021-9983 .- 1530-793X. ; 54:26, s. 3999-4009
  • Tidskriftsartikel (refereegranskat)abstract
    • In this article, tailored temperature zones are used to obtain improved quality during rapid, high pressure forming of multi-stacked unidirectional prepreg. Particularly in aerospace applications, commonly used forming processes for multi-stacked unidirectional prepreg are often considered a bottleneck in production since the forming cycle requires both heating and cooling ramps and consequently takes long time—often about 1 h. It is possible to speed up the process by using elevated pressure and temperature. However, higher pressure and temperature also increase the influence of pressure gradient-driven, in-plane material movement (squeeze flow). This typically appears as radius thinning when forming a C-spar geometry on a male mold. Decrease of lay-up temperature will decrease radius thinning, but due to obstructed interply slippage, instead bending-induced wrinkles appear on the spar flange. In this article, tailored temperatures at the radius and in the flange area are introduced by using a hot lay-up and a cold mold. The results show that temperature differences of 6℃–10℃ between the radius area and the flange edge of the lay-up decreases radius thinning while still avoiding bending-induced wrinkles. Except from the radius temperature also the stacking sequence and the choice of prepreg system showed a significant influence on the radius thinning.
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33.
  • Hansson, Jonas, 1971-, et al. (författare)
  • Coercive measures against minors in the Swedish asylum process : legal uncertainty, ambivalence and experiences of intrusiveness
  • 2023
  • Ingår i: Nordic Journal of Social Research. - : Universitetsforlaget. - 1892-2783. ; 14:1, s. 1-21
  • Tidskriftsartikel (refereegranskat)abstract
    • Asylum-seeking minors are viewed as particularly vulnerable but are still exposed to coercive measures permitted by law. This study analyses Swedish Police Authority and Swedish Migration Agency officials’ perceptions of coercive measures towards minors in the asylum process in light of the Swedish law, and raises minors’ own voices on their experiences of coercive measures. Qualitative interviews were performed with 1) officials at the Swedish Police Authority and Swedish Migration Agency who manage and use coercive actions against minors and 2) former minors with experiences of being subjected to coercive measures. Based on a thematic analysis, the results illustrate how the officials’ perceptions about coercive measures are characterized by uncertainty and ambivalence. The minors expressed the importance of how they were treated during the asylum process rather than the coercive measure as such. Swedish law regulating coercive measures needs clarifications to give sufficient guidance for practice.
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34.
  • Hjertstedt, Mattias, 1974-, et al. (författare)
  • Åldersbedömningar i svensk asylprocess - Gräsrotsbyråkrati eller expertstyre?
  • 2024
  • Ingår i: Socialmedicinsk Tidskrift. - 0037-833X. ; 101:1, s. 57-70
  • Tidskriftsartikel (refereegranskat)abstract
    • Syftet med denna artikel är att utforska hur centrala svenska aktörer upplever och hanterar arbetet med åldersbedömningar av asylsökande barn i Sverige. Vidare syftar artikeln till att diskutera hur dessa aktörer använder sitt handlingsutrymme till att balansera mellan den rättsliga regleringen å den ena sidan och barnets rättigheter och behov å den andra. I artikeln används Lipskys teori om gräsrotsbyråkrater. Undersökningen baseras på kvalitativa semi-strukturerade intervjuer med tjänstepersoner vid Migrationsverket och rättsläkare. Av resultaten dras slutsatsen att tjänstepersonerna vid Migrationsverket har ett stort handlingsutrymme vid åldersbedömning av asylsökande barn, men att de i hög grad använder detta till att överlämna beslutet om ålder till rättsläkarna. Vidare dras slutsatsen att rättsläkarna har ett mer begränsat handlingsutrymme, eftersom det är utlåtanden från tandläkare och röntgenläkare som egentligen avgör vilken åldersbedömning som görs.
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35.
  • Jemberie, Wossenseged Birhane, 1985-, et al. (författare)
  • "Ageing with an alcohol problem is not what I envision" : reclaiming agency in shaping personal ageing trajectory and recovery from alcohol problems
  • 2023
  • Ingår i: BMC Geriatrics. - : BioMed Central (BMC). - 1471-2318. ; 23
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Eliciting and understanding older persons’ descriptions of their resources for healthy ageing and the interaction of these resources with alcohol use and alcohol problems can facilitate health promotion. It can also inform clinicians when identifying areas of recovery capital that present risks and strength for older people seeking alcohol treatment. The objective of this study was to illuminate the experiences and perspectives of older persons on ageing, alcohol use, treatment, and recovery from alcohol problems, as well as their understanding of healthy ageing.Methods: Eight men and two women, aged 61 to 73 years, with moderate drinking as a treatment goal and treated at an outpatient alcohol clinic in Sweden, participated in semi-structured audio-recorded virtual interviews. A qualitative content analysis examined the transcribed interviews.Results: Three themes were identified: “Tipping the balance”, “Staying behind a veil” and “Lifting the vail”. First, participants understood healthy ageing as a personal and multidimensional process that involved actively expanding, maintaining or adjusting to the resources needed to lead an active and meaningful life while preserving autonomy, dignity and independence for as long as possible. Second, most participants viewed moderate alcohol use as a contributor to healthy ageing. They sought treatment when their drinking became unsustainable and an immediate threat to their healthy ageing resources. Stigma, ambivalence and a lack of treatment options, however, contributed to delayed treatment. Third, the participants responded to treatment approaches that elicited their concern, incorporated their expertise and treatment and life goals, appreciated their autonomy and agency, and considered them partners in goal setting and decision making. Reduced drinking helped participants regain their agency and improved their healthy ageing capital which in turn catalyzed continuing recovery.Conclusions: Older persons in non-abstinent recovery perceive healthy ageing and alcohol recovery as personal and interacting multidimensional processes involving their agency to improve biopsychosocial functioning. Treatment approaches that recognize older persons’ desire for healthy ageing, incorporate their treatment goals and respect their autonomy are likely to be acceptable and effective.
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36.
  • Jemberie, Wossenseged Birhane, 1985- (författare)
  • Alcohol and aging : a multimethod study on heterogeneity and multidimensionality
  • 2023
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background and Objectives: With an ageing population, the number of older persons with substance use problems, particularly problematic alcohol use, is increasing. Despite grow­ing recognition of the negative consequences of problematic alcohol use on older persons, there is a dearth of knowledge about the alcohol use profiles and the dimensionality of alcohol problems in older people. Moreover, little is known about older persons’ experi­ences and perspectives on alcohol use in relation to their ageing and their personal goals regarding treatment and recovery. This thesis aimed to (i) describe the characteristics of older persons who accessed municipal substance use treatment and care services (addic­tion services) and to investigate their future hospitalization; (ii) examine the heterogeneity and multidimensionality of problematic alcohol use among older persons; and (iii) to shed light on the experiences and perspectives of older persons regarding ageing, alcohol prob­lems and recovery.Methods: For studies I-III, municipal Addiction Severity Index (ASI) assessment data (between 2003 and 2017) from adults aged 50 years and older were used to select the study samples. Generalized linear regression models investigated hospitalization related out­comes among 3624 older persons in Study-I. In Study-II, a latent class analysis was applied on ASI data from 1747 individuals with alcohol problems. Study-III linked the ASI data from Study-II to hospital discharge and mortality data forming time-to-repeated-event dataset; Andersen-Gill regression model with a robust variance estimator was used for the analysis. Study-IV applied qualitative content analysis on interview data from ten older persons re­cruited from a specialist outpatient clinic for alcohol treatment. Results: Nearly three-fourth of older persons assessed for substance use severity at municipal addiction services were later hospitalized (Study-I). Individuals diagnosed with substance use disorders, psychiatric or dual diagnoses had more cumulative hospitalized days, higher rates of hospital readmissions, and shorter time to first admission following an initial ASI assessment at municipal addiction services (Study-I). Five distinct groups of older persons with comparable alcohol problem severity but with variation in onset age, psychiatric comorbidities, polysubstance use, social support and gender composition were identified (Study-II). The five groups varied in risks of repeated hospitalizations due to substance use and psychiatric disorders (Study-III). Older persons experienced their ageing and alcohol use having a dynamic interplay (Study-IV). They needed to constantly negotiate with their environment to maintain a positive ageing trajectory. They perceived moderate alcohol use fosters healthy ageing, but over time, experienced their alcohol use as unsustainable and a threat to their pursuit of healthy ageing. Stigma and ambivalence delayed treatment seeking (Study-IV). They accessed treatment programs which re­spected their preferences and autonomy, engaged them in goal setting and strengthened their agency. After reducing their alcohol use, positive changes in their biopsychosocial functioning encouraged them to continue their recovery journey even in the presence of setbacks (Study-IV).Conclusion: Most older persons who access municipal addiction services are hospitalized repeatedly. Many older persons with alcohol problems live with medical and psychiatric comorbidities suggesting multiple care needs from health and social care services. Incor­porating older persons’ desire for healthy ageing into alcohol treatment plan can facilitate treatment engagement and recovery. Many older persons aim to moderate their alcohol consumption. Clinicians can deliver person-centered care for older persons, by consider­ing their heterogeneity in treatment goals, biopsychosocial functioning, and available re­sources. A multidimensional identification of alcohol use profiles could improve treatment by establishing the variation in alcohol problems among older treatment seekers. Older persons stay engaged in alcohol treatment programs which value their experiences and expertise, incorporate their personal treatment and life goals, respect their autonomy and agency, and involve them as active participants. Sensitizing service providers on old age substance use problems could provide multiple points of contact for screening of older persons and earlier referral to treatment. A streamlined data sharing within and between health and social care services fosters timely and equitable care and facilitates an inte­grated and person-centered care across the continuum. 
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37.
  • Jemberie, Wossenseged Birhane, 1985-, et al. (författare)
  • Studying the trajectories and mediators of old-age problematic alcohol use and the agency of older persons
  • 2023
  • Annan publikationabstract
    • Unit of analysis: IndividualPopulation: Older people aged between 61 and 73 years who have sought treatment for alcohol at a specialist outpatient clinic in a metropolitan city in Sweden.Time Method: Cross-sectionSampling procedure: Non-probability: PurposiveThe study participants were purposefully recruited from a specialist outpatient alcohol treatment clinic located in a Swedish metropolitan city. To be eligible for the study, participants had to be 55 years or older, had to self-report a history of problematic alcohol use and treatment for alcohol use after the age of 50. Individuals who were unable or unwilling to provide informed consent or participate in the interview via Zoom, Skype, or telephone were excluded from the study.Time period(s) investigated: 2021-12 – 2022-04Number of individuals/objects: 10Data format / data structure: Text
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38.
  • Jemberie, Wossenseged Birhane, 1985-, et al. (författare)
  • Substance Use Disorders and COVID-19 : Multi-Faceted Problems Which Require Multi-Pronged Solutions
  • 2020
  • Ingår i: Frontiers in Psychiatry. - : Frontiers Media S.A.. - 1664-0640. ; 11
  • Tidskriftsartikel (refereegranskat)abstract
    • COVID-19 shocked health and economic systems leaving millions of people without employment and safety nets. The pandemic disproportionately affects people with substance use disorders (SUDs) due to the collision between SUDs and COVID-19. Comorbidities and risk environments for SUDs are likely risk factors for COVID-19. The pandemic, in turn, diminishes resources that people with SUD need for their recovery and well-being. This article presents an interdisciplinary and international perspective on how COVID-19 and the related systemic shock impact on individuals with SUDs directly and indirectly. We highlight a need to understand SUDs as biopsychosocial disorders and use evidence-based policies to destigmatize SUDs. We recommend a suite of multi-sectorial actions and strategies to strengthen, modernize and complement addiction care systems which will become resilient and responsive to future systemic shocks similar to the COVID-19 pandemic.
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39.
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40.
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41.
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42.
  • Lantero Rodriguez, Marta, et al. (författare)
  • Testosterone reduces metabolic brown fat activity in male mice
  • 2021
  • Ingår i: Journal of Endocrinology. - : Bioscientifica. - 0022-0795 .- 1479-6805. ; 251:1, s. 83-96
  • Tidskriftsartikel (refereegranskat)abstract
    • Brown adipose tissue (BAT) burns substantial amounts of mainly lipids to produce heat. Some studies indicate that BAT activity and core body temperature are lower in males than females. Here we investigated the role of testosterone and its receptor (the androgen receptor; AR) in metabolic BAT activity in male mice. Castration, which renders mice testosterone deficient, slightly promoted the expression of thermogenic markers in BAT, decreased BAT lipid content, and increased basal lipolysis in isolated brown adipocytes. Further, castration increased the core body temperature. Triglyceride-derived fatty acid uptake, a proxy for metabolic BAT activity in vivo, was strongly increased in BAT from castrated mice ( 4.5-fold increase vs sham-castrated mice) and testosterone replacement reversed the castration-induced increase in metabolic BAT activity. BAT-specific AR deficiency did not mimic the castration effects in vivo and AR agonist treatment did not diminish the activity of cultured brown adipocytes in vitro, suggesting that androgens do not modulate BAT activity via a direct, AR-mediated pathway. In conclusion, testosterone is a negative regulator of metabolic BAT activity in male mice. Our findings provide new insight into the metabolic actions of testosterone.
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43.
  • Lestari, Septi K., et al. (författare)
  • A longitudinal study on social support, social participation, and older Europeans' Quality of life
  • 2021
  • Ingår i: Ssm-Population Health. - : Elsevier BV. - 2352-8273. ; 13
  • Tidskriftsartikel (refereegranskat)abstract
    • The association between quality of life (QoL) and social relationships is well established. This paper further analyses whether and how participation in social activities as well as providing and receiving social support, independently, are associated with QoL among the older population in 16 European countries. QoL was measured using the CASP-12 scale. The baseline data came from Wave 6 and the outcome from Wave 7 of the Survey of Health, Ageing and Retirement in Europe (SHARE). The associations of interest were analysed using multivariable linear regression. The effect of possible non-ignorable dropout was tested. Then, doubly robust estimation and sensitivity analyses for unobserved confounding were performed to evaluate the possible causal interpretation of the associations found. Our findings show that participation in at least one of the socially productive activities was positively associated with QoL at two-year follow-up (Average Causal Effect, ACE: 0.474; 95%CI: 0.361, 0.587). The association was stronger among women, people aged 75+, and those in the Southern European region. Providing social support had a positive association with QoL, but only among people aged 75+ (ACE: 0.410; 95%CI: 0.031, 0.789). Conversely, receiving social support had a negative association (ACE: -0.321; 95%CI: -0.448, -0.195) with QoL, especially for men, people aged 75+, and those in Eastern European countries. Sensitivity analyses for unobserved confounders showed that the associations found cannot be attributed to causal effects.
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44.
  • Lestari, Septi Kurnia, 1989- (författare)
  • Active and healthy ageing in Europe : significance of social relationships
  • 2022
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Social relationships have important roles in achieving active and healthy ageing. Social relationships are dynamic across the life course. A myriad of contextual and individual (e.g., sociodemographic and health-related) factors shape the levels of social relationship constructs (e.g., social contact, participation, and support) and how they change over time. This thesis aims to contribute to a better understanding of social relationships among the older European population, the impact of health on social relationships, the influence of social relationships on quality of life, and the impact of the COVID-19 pandemic on the levels of social relationships.Methods: The study subjects were community-dwelling Europeans aged 50 and over who participated in the Survey of Health, Ageing and Retirement in Europe (SHARE) between 2004 and 2020. In Sub-study 1, multilevel growth modelling was used to analyse the trajectories of seven social relationship constructs, i.e., provision and receipt of instrumental support, social contact, and participation in volunteer work, sport/social club, educational activity, and political/community organisation. Sub-study 2 used latent class analysis (LCA) to identify social relationship typologies based on the seven social relationship constructs and perceived emotional support. Next, the associations between frailty and social relationship typologies were analysed using LCA-with-covariates. Sub-study 3 evaluated the possible causal effect of social support provision, support receipt, and participation on quality of life using doubly robust estimation and sensitivity analysis for unobserved confounding. Sub-study 4 used multilevel logistic regression analysis to determine whether individuals’ exposure to COVID-19 and the country’s COVID-19 policies stringency index (S-Index) were associated with the initiation of provision and receipt of instrumental support and volunteering during the first phase of the COVID-19 pandemic. Results: In contrast to instrumental support receipt, the probability of instrumental support provision, social contact, and participation declined slightly over time (Sub-study 1). Four social relationship types were identified: 1) poor, 2) frequent and emotionally close, 3) frequent, emotionally close, and supportive, and 4) frequent, emotionally close, and active (Sub-study 2). Poor self-rated health limited instrumental support provision and increased instrumental support receipt from outside the household (Sub-study 1). Being pre-frail or frail was associated with less active social relationship types, i.e., Types 1, 2, and 3 (Sub-study 2). Social participation and instrumental support provision for people outside the household were correlated with a higher quality of life while receiving instrumental support was associated with a lower quality of life. None of these associations could be considered causal (Sub-study 3). During the COVID-19 pandemic, the level of volunteering and instrumental support provision was lower, but the level of instrumental support receipt was higher than before the pandemic. Being exposed to COVID-19 was positively associated with support receipt initiation. The close ones’ exposure to COVID-19 was positively associated with volunteering, support provision, and support receipt. S-Index was positively associated with instrumental support provision initiation but negatively associated with support receipt initiation (Sub-study 4).Conclusions: A significant share of older Europeans was socially active. Their engagement in social contact, support, and participation changed over time. The four social relationship types revealed the importance of having frequent contact in initiating instrumental support exchange and social participation. Health is a vital determinant of older adults’ social relationships. On the other hand, observed associations indicate that social relationships may influence older adults’ quality of life. The pandemic might lower social support provision and volunteering and increase support receipt levels in the population. However, the pandemic might also encourage older adults to provide help, likely to people within their neighbourhood. Overall, maintaining close social ties, especially with family and close friends, is important to stimulate active engagement in social support exchange and participation, which promotes healthy ageing.
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45.
  • Lestari, Septi K., et al. (författare)
  • Changes in the provision of instrumental support by older adults in nine European countries during 2004-2015: a panel data analysis
  • 2020
  • Ingår i: BMC Geriatrics. - : Springer Science and Business Media LLC. - 1471-2318. ; 20:1
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundProviding support to others has been shown to be beneficial to older adults. As people age, their health and social relationships change. These changes may also relate to changes in social support provision. We examined the trajectory of instrumental support provision by older people in three European regions throughout 11 years of follow-up. We then examined the extent to which age at baseline, sex, and region (representing welfare state regime) influenced the variations in the trajectory.MethodsData collected from 8354 respondents who had completed at least waves 1 and 6 of the Survey of Health, Ageing and Retirement in Europe (SHARE) was analysed. Instrumental support provision was determined from asking a single question regarding whether the respondent provided help personally for people outside their household. Region, sex, and age at baseline were the main predictors tested. We used growth modelling to address the aims of this study.ResultsThe northern European region (Sweden and Denmark) had the highest odds ratio of instrumental support provision. The likelihood of being involved in providing instrumental support decreased by 8% annually (OR: 0.916, 95%CI: 0.893,0.940) over the 11 years of follow-up. Older respondents were less likely to provide instrumental support and their trajectories declined faster than those of the younger respondents. Sex difference in instrumental support provision was more apparent among younger-older people in the southern European region.ConclusionsOlder European adults are an important source of instrumental support, especially for their families. The probability of instrumental support provision by European older adults declines over time. Age, sex, and welfare state regime predict this trajectory.
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46.
  • Lestari, Septi K, et al. (författare)
  • Frailty and types of social relationships among older adults in 17 European countries: A latent class analysis
  • 2022
  • Ingår i: Archives of Gerontology and Geriatrics. - : Elsevier BV. - 0167-4943 .- 1872-6976. ; 101
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Frailty is a syndrome commonly associated with old age. Social relationships are an essential determinant of frailty progression, and frailty can negatively affect social relationships. Objectives: To identify social relationship types among older adults in Europe; to evaluate whether social relationship types differ across European regions; and to assess the association between frailty status and social relationship type.& nbsp;& nbsp;Methods: We used data from 56,226 individuals from 17 European countries who participated in Wave 6 of the Survey of Health, Ageing and Retirement in Europe. We constructed social relationship types from social relationship variables (contacts frequency, perceived emotional support, participation in social activities, providing and receiving instrumental support) using latent class analysis (LCA). Associations between social relationship types and frailty were examined using multinomial regression analyses integrated with LCA.& nbsp;Results: We identified four social relationship types: 'poor'; 'frequent and emotionally close'; 'frequent, emotionally close, and supportive'; and 'frequent, emotionally close, and active'. Type 3 is also characterised by participation in sport/social clubs (in the northern region) or receiving support (in the eastern region). Participation in volunteering/charity activities (in the central and northern regions) and instrumental support provision (in the northern region) are Type 4 & PRIME;s characteristics as well. In all regions, being frail was associated with less active social relationships (Types 1, 2, and 3) relative to the more 'active' type (Type 4).& nbsp;Conclusion: Frailty status was associated with social relationship types. The identified types may help tailor intervention programmes for older adults to prevent worsening frailty.
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47.
  • Lestari, Septi Kurnia, 1989-, et al. (författare)
  • Volunteering and instrumental support during the first phase of the pandemic in Europe : the significance of COVID-19 exposure and stringent country’s COVID-19 policy
  • 2024
  • Ingår i: BMC Public Health. - : BioMed Central (BMC). - 1471-2458. ; 24:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The COVID-19 control policies might negatively impact older adults’ participation in volunteer work, instrumental support provision, and the likelihood of receiving instrumental support. Studies that quantify changes in these activities and the related factors are limited. The current study aimed to examine the level of volunteering, instrumental support provision and receipt before and during the first phase of the COVID-19 pandemic in Europe and to determine whether older adults’ volunteering, instrumental support provision and receipt were associated with individual exposure to COVID-19 and the stringency of country’s COVID-19 control policy during the first phase of the COVID-19 pandemic.Methods: A cross-sectional survey using data from the Survey of Health, Ageing and Retirement in Europe (SHARE) Corona Survey 1 was designed to focus on community-dwelling Europeans aged ≥50 years. History of participation in volunteering work and instrumental support provision or receipt was assessed from the previous SHARE Wave data. The country’s COVID-19 control policy stringency index (S-Index) was from the Oxford COVID-19 Government Response Tracker database. A total of 45,669 respondents from 26 European countries were included in the volunteering analysis. Seventeen European countries were included in the analyses of instrumental support provision (N = 36,518) and receipt (N = 36,526). The multilevel logistic regression model was fitted separately to analyse each activity.Results: The level of volunteering and instrumental support provision was lower during the pandemic, but instrumental support receipt was higher. The country S-Index was positively associated with support provision (OR:1.13;95%CI:1.02–1.26) and negatively associated with support receipt (OR:0.69;95%CI:0.54–0.88). Exposure to COVID-19 was positively associated with support receipt (OR:1.64;95%CI:1.38–1.95). COVID-19 exposure on close ones positively associated with volunteering (OR:1.47;95%CI:1.32–1.65), support provision (OR:1.28;95%CI:1.19–1.39), and support receipt (OR:1.25;95%CI:1.15–1.35).Conclusions: The COVID-19 pandemic impacted older Europeans’ volunteering, instrumental support provision, and instrumental support receipt from outside their household. When someone close to them was exposed to COVID-19, older Europeans were likely to receive instrumental support and to volunteer and provide instrumental support. A stricter country’s COVID-19 control policy might motivate older adults to provide instrumental support, but it prevents them from receiving instrumental support from outside their households. 
  •  
48.
  • Lundström, Sara, 1981, et al. (författare)
  • Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms
  • 2016
  • Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697 .- 1879-1026. ; 553, s. 587-95
  • Tidskriftsartikel (refereegranskat)abstract
    • Selection pressure generated by antibiotics released into the environment could enrich for antibiotic resistance genes and antibiotic resistant bacteria, thereby increasing the risk for transmission to humans and animals. Tetracyclines comprise an antibiotic class of great importance to both human and animal health. Accordingly, residues of tetracycline are commonly detected in aquatic environments. To assess if tetracycline pollution in aquatic environments promotes development of resistance, we determined minimal selective concentrations (MSCs) in biofilms of complex aquatic bacterial communities using both phenotypic and genotypic assays. Tetracycline significantly increased the relative abundance of resistant bacteria at 10 μg/L, while specific tet genes (tetA and tetG) increased significantly at the lowest concentration tested (1 μg/L). Taxonomic composition of the biofilm communities was altered with increasing tetracycline concentrations. Metagenomic analysis revealed a concurrent increase of several tet genes and a range of other genes providing resistance to different classes of antibiotics (e.g. cmlA, floR, sul1, and mphA), indicating potential for co-selection. Consequently, MSCs for the tet genes of ≤ 1 μg/L suggests that current exposure levels in e.g. sewage treatment plants could be sufficient to promote resistance. The methodology used here to assess MSCs could be applied in risk assessment of other antibiotics as well.
  •  
49.
  • Ng, Nawi, 1974, et al. (författare)
  • Sustainable Behavior Change for Health Supported by Person-Tailored, Adaptive, Risk-Aware Digital Coaching in a Social Context: Study Protocol for the STAR-C Research Programme
  • 2021
  • Ingår i: Frontiers in Public Health. - : Frontiers Media SA. - 2296-2565. ; 9
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: The Vasterbotten Intervention Programme (VIP) in the Region Vasterbotten Sweden is one of the very few cardiovascular disease (CVD) prevention programmes globally that is integrated into routine primary health care. The VIP has been shown as a cost-effective intervention to significantly reduce CVD mortality. However, little is known about the effectiveness of a digital solution to tailor risk communication strategies for supporting behavioral change. STAR-C aims to develop and evaluate a technical platform for personalized digital coaching that will support behavioral change aimed at preventing CVD. Methods: STAR-C employs a mixed-methods design in seven multidisciplinary projects, which runs in two phases during 2019-2024: (i) a formative intervention design and development phase, and (ii) an intervention implementation and evaluation phase. In the 1st phase, STAR-C will model the trajectories of health behaviors and their impact on CVDs (Project 1), evaluate the role of the social environment and social networks on behavioral change (Project 2) and assess whether and how social media facilitates the spread of health information beyond targeted individuals and stimulates public engagement in health promotion (Project 3). The findings will be utilized in carrying out the iterative, user-centered design, and development of a person-tailored digital coaching platform (Project 4). In the 2nd phase, STAR-C will evaluate the implementation of the coaching programme and its effectiveness for promoting behavioral change and the spreading of health information across social networks and via social media (Project 5). The cost-effectiveness (Project 6) and ethical issues (Project 7) related to the coaching programme intervention will be evaluated. Discussion: The STAR-C research programme will address the knowledge and practice research gaps in the use of information technologies in health promotion and non-communicable disease (NCD) prevention programmes in order to narrow the health inequality gaps. Ethics: STAR-C has received approval from the Swedish Ethical Review Authority (Dnr. 2019-02924;2020-02985). Dissemination: The collaboration between Umea University and Region Vasterbotten will ensure the feasibility of STAR-C in the service delivery context. Results will be communicated with decision-makers at different levels of society, stakeholders from other regions and healthcare professional organizations, and through NGOs, local and social media platforms.
  •  
50.
  • Nygren, Lennart, 1953-, et al. (författare)
  • Diskontinuitet i sociala barnavårdsprocesser : från risktecken till vuxenliv
  • 2020
  • Ingår i: Socionomens forskningssupplement. - : Akademikerförbundet SSR. - 0283-1929. ; :48, s. 18-29
  • Tidskriftsartikel (refereegranskat)abstract
    • Artikeln beskriver och analyserar förekomst och erfarenheter av diskontinuitet för unga vuxna under deras väg som föremål för samhällets insatser. Underlaget består av detaljerade studier av akt- och journaldata, kombinerat med livshistoriska intervjuer med ett tjugotal unga vuxna med erfarenheter av placering i samhällsvård. Studien visar att diskontinuiteter förekommer i olika faser i samhällets insatser: i tiden mellan första dokumentation av risktecken och de första åtgärderna från socialtjänsten; i de besluts- och insatsprocesser som sker i tidsspannet mellan första åtgärd och den tidpunkt då den unge lämnar samhällsvården; samt, i övergången mellan samhällsvårdens avslutning och den unges självständiga vuxenliv. Diskontinuitet kan vara kontextuellt och individuellt betingad och kopplad till administrativ hantering, relationer, informationsflöden eller vara erfaren eller associerad med problematikens allvarlighetsgrad. I många fall kan diskontinuitetsproblem ge negativa erfarenheter för unga i samhällsvård.
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