| 1. |
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| 2. |
- Andersson, Sören, et al.
(författare)
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Säsongslagring av värme i berg
- 1981
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Ingår i: Byggnadskonst. - 0007-7593. ; 73:11, s. 45-47
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 3. |
- Ank, Nina, et al.
(författare)
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Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo.
- 2006
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Ingår i: Journal of virology. - 0022-538X. ; 80:9, s. 4501-9
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Tidskriftsartikel (refereegranskat)abstract
- Type III interferons (IFNs) (interleukin-28/29 or lambda interferon [IFN-lambda]) are cytokines with IFN-like activities. Here we show that several classes of viruses induce expression of IFN-lambda1 and -lambda2/3 in similar patterns. The IFN-lambdas were-unlike alpha/beta interferon (IFN-alpha/beta)-induced directly by stimulation with IFN-alpha or -lambda, thus identifying type III IFNs as IFN-stimulated genes. In vitro assays revealed that IFN-lambdas have appreciable antiviral activity against encephalomyocarditis virus (EMCV) but limited activity against herpes simplex virus type 2 (HSV-2), whereas IFN-alpha potently restricted both viruses. Using three murine models for generalized virus infections, we found that while recombinant IFN-alpha reduced the viral load after infection with EMCV, lymphocytic choriomeningitis virus (LCMV), and HSV-2, treatment with recombinant IFN-lambda in vivo did not affect viral load after infection with EMCV or LCMV but did reduce the hepatic viral titer of HSV-2. In a model for a localized HSV-2 infection, we further found that IFN-lambda completely blocked virus replication in the vaginal mucosa and totally prevented development of disease, in contrast to IFN-alpha, which had a more modest antiviral activity. Finally, pretreatment with IFN-lambda enhanced the levels of IFN-gamma in serum after HSV-2 infection. Thus, type III IFNs are expressed in response to most viruses and display potent antiviral activity in vivo against select viruses. The discrepancy between the observed antiviral activity in vitro and in vivo may suggest that IFN-lambda exerts a significant portion of its antiviral activity in vivo via stimulation of the immune system rather than through induction of the antiviral state.
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| 4. |
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| 5. |
- Bengtsson, Maria, et al.
(författare)
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Innovationer gynnas av både konkurrens och samarbete
- 2008
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Ingår i: Marknadsorientering. - : Liber AB Malmö. - 9789147088928 ; , s. 239-256
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Bokkapitel (refereegranskat)abstract
- De myter som diskuteras i detta kapitel är att antingen konkurrens eller samarbete utgör det bästa receptet för att stödja innovationsprocesser.En orsak till att myterna fått så stor genomslagskraft är att konkurrens och samarbete sällan diskuteras kopplat till vad somutgör innovativa processer, nämligen förmogan att utforska och exploatera nya idéer. Det är därför viktigt att man avfärdar de båda myterna och istället inser att konkurrens och samarbete pågår samtidigt, så kallad coopetition.Både konkurrens och samarbete kan stimulera och försvåra innovativa processer om än på olika sätt under olika delar av den innovativa processen. I kapitlet visas med hjälp av några praktiska exempel hur olika kombinationer av konkurrens och samarbete stimulerar förmågan att utforska respektive exploatera nya idéer.
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| 6. |
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| 7. |
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| 8. |
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| 9. |
- Bergström, Petra, et al.
(författare)
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Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons
- 2021
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Ingår i: Viruses-Basel. - : MDPI AG. - 1999-4915. ; 13:10
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Tidskriftsartikel (refereegranskat)abstract
- Herpes simplex virus 1 (HSV-1) and 2 (HSV-2) can infect the central nervous system (CNS) with dire consequences; in children and adults, HSV-1 may cause focal encephalitis, while HSV-2 causes meningitis. In neonates, both viruses can cause severe, disseminated CNS infections with high mortality rates. Here, we differentiated human induced pluripotent stem cells (iPSCs) towards cortical neurons for infection with clinical CNS strains of HSV-1 or HSV-2. Progenies from both viruses were produced at equal quantities in iPSCs, neuroprogenitors and cortical neurons. HSV-1 and HSV-2 decreased viability of neuroprogenitors by 36.0% and 57.6% (p < 0.0001), respectively, 48 h post-infection, while cortical neurons were resilient to infection by both viruses. However, in these functional neurons, both HSV-1 and HSV-2 decreased gene expression of two markers of synaptic activity, CAMK2B and ARC, and affected synaptic activity negatively in multielectrode array experiments. However, unaltered secretion levels of the neurodegeneration markers tau and NfL suggested intact axonal integrity. Viral replication of both viruses was found after six days, coinciding with 6-fold and 22-fold increase in gene expression of cellular RNA polymerase II by HSV-1 and HSV-2, respectively. Our results suggest a resilience of human cortical neurons relative to the replication of HSV-1 and HSV-2.
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| 10. |
- Bernhardsson, Christian, et al.
(författare)
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Environmental radiation baseline around the Belarusian nuclear power plant – assessments in Belarus and Lithuania
- 2023
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Ingår i: Medical Physics in the Baltic States : Proceedings of the 16<sup>th</sup> International Conference on Medical Physics - Proceedings of the 16<sup>th</sup> International Conference on Medical Physics. - 1822-5721. ; , s. 121-125
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Konferensbidrag (refereegranskat)abstract
- Prior to the operation of the first Belarussian nuclear power plant (BelNPP), the baseline of the radiation environment was determined within a radius of about 30 km from BelNPP. This independent assessment was carried out during two expeditions in 2019. In 2022, a similar survey was carried out (during the initialoperation of BelNPP) on the Lithuanian side of the boarder. Here we present the overall project and some general results of the baseline assessments.
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| 11. |
- Bernhardsson, Christian, et al.
(författare)
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Radiological environmental monitoring at the ESS facility – Annual report 2020
- 2021
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Results from the radiological environmental monitoring of the European Spallation Source (ESS) are presented for year 2020.Among the 63 environmental samples analysed for gamma emitting radionuclides, no elevated levels of anthropogenic radioactivity were observed. All samples (except two samples of lichen) had activity concentrations below the MDA for the natural radionuclides as well as 137Cs, and normal levels of 40K. In sewage sludge, detectable levels of 177Lu and 1311 were observed in samples that were measured within one week after sampling.Mobile gamma spectrometry surveys were carried out around ESS and MAX IV (when operating at high frequency during a test run). No deviating radiation levels were observed.The samples analysed for their 3H activity concentration (120 samples) were generally below the detection limit using the current procedure, instrumentation and analysis time (MDA typically 1.6 Bq L-1). The results show no evidence of any local contamination of 3H in Lund during 2020.The 14C data in the 26 samples of grass, fruits, berries, crops, milk, honey and meat of in the Lund area and in southern Sweden is consistent with the declining 14C specific activity in atmospheric CO2. Seasonal variations were observed in the 14C data. No evidence of anthropogenic 14C contamination in the Lund area was noted during 2020.The report presents the first base-line measurements of 129I (10 samples) in the ESS environmental monitoring programme. The 129I activity concentrations ranged between (3.18 ± 0.20)∙1011 atoms/kg d.w. for grass and (1.31 ± 0.03)∙1013 atoms/kg d.w. for moss. These values are in the expected range.
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| 12. |
- Bernhardsson, Christian, et al.
(författare)
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ZERO POINT ASSESSMENT OF THE RADIATION ENVIRONMENT – EXAMPLES OF A PROGRAM APPLIED IN SWEDEN (ESS) AND IN BELARUS (BELNPP)
- 2019
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Ingår i: MEDICAL PHYSICS IN THE BALTIC STATES : Proceedings of the 14th International Conference on Medical Physics - Proceedings of the 14th International Conference on Medical Physics. ; , s. 85-88
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Konferensbidrag (refereegranskat)abstract
- Before commissioning of a nuclear facility it is important to determine the baseline of the radiation environment. Such baseline or Zero Point assessments can only,and uniquely, be made before start of operation of the facility and will serve several purposes when the facility is in operation. Here we report on the planning and implementation of such a Zero Point program for achieving high reproducibility and effectiveness of the assessments around two nuclear installations.
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| 13. |
- Bignert, Anders, et al.
(författare)
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Temporal trends of organochlorines in Northern Europe, 1967–1995. Relation to global fractionation, leakage from sediments and international measures
- 1998
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Ingår i: Environmental Pollution. - 0269-7491 .- 1873-6424. ; 99:2, s. 177-198
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Tidskriftsartikel (refereegranskat)abstract
- The time trend monitoring of organochlorine pollution was carried out in Sweden since the late 1960s. This report presents data on concentrations of DDT, PCB, HCHs and HCB in biota samples collected and analysed annually. All the matrices and compounds studied show a significant decrease over time. The data cover severely polluted Swedish marine and fresh water in southern Sweden as well as locally unpolluted waters in remote northern Arctic regions of Sweden. A total of 13 time series representing different locations and species are presented for the different pollutants. The period studied covers the time when pollution was serious as well as the time of recovery. All monitoring activities were carried out at the same laboratories over the entire study period, which means that comparability over time is good in the sets of data presented. The various time trends show a convincing agreement with trends and annual change over time, although the concentrations differ between the species and locations investigated, the highest concentrations being in the south. Since the annual changes are normally similar regardless of locations and species, spatial variations in concentrations remain over time, although concentrations are lower today. The onset of changes in concentrations over time can be related to international measures or other circumstances that lowered releases into the environment. Similarities in the annual changes, as well as the time when changes began, are discussed with respect to suggested hypotheses on the fate of the investigated organochlorines. It was not possible to verify that the oxygenation of anoxic sediments mobilised old pollution in Baltic sediments. Neither was it possible to conclude that eutrophication has caused a measurable effect on the rate and timing of the decreases. Finally, long-range transport to Arctic regions seems to be due more to a one step transport than to the ‘Grass-hopper’ effect. The comprehensive database used, clearly shows how important it is to have datasets big enough to describe between-year variation before attempting to evaluate the time trend. In addition, if between-year variation is not known, it is then also difficult to evaluate spatial variation on the basis of single year observations.
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| 14. |
- Blomstrand, Malin, et al.
(författare)
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Estimated clinical benefit of protecting neurogenesis in the developing brain during radiation therapy for pediatric medulloblastoma.
- 2012
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Ingår i: Neuro-Oncology. - : Oxford University Press (OUP). - 1523-5866 .- 1522-8517. ; 14:7, s. 882-889
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Tidskriftsartikel (refereegranskat)abstract
- We sought to assess the feasibility and estimate the benefit of sparing the neurogenic niches when irradiating the brain of pediatric patients with medulloblastoma (MB) based on clinical outcome data. Pediatric MB survivors experience a high risk of neurocognitive adverse effects, often attributed to the whole-brain irradiation that is part of standard management. Neurogenesis is very sensitive to radiation, and limiting the radiation dose to the hippocampus and the subventricular zone (SVZ) may preserve neurocognitive function. Radiotherapy plans were created using 4 techniques: standard opposing fields, intensity-modulated radiotherapy (IMRT), intensity-modulated arc therapy (IMAT), and intensity-modulated proton therapy (IMPT). Mean dose to the hippocampus and SVZ (mean for both sites) could be limited to 88.3% (range, 83.6%-91.0%), 77.1% (range, 71.5%-81.3%), and 42.3% (range, 26.6%-51.2%) with IMAT, IMRT, and IMPT, respectively, while maintaining at least 95% of the prescribed dose in 95% of the whole-brain target volume. Estimated risks for developing memory impairment after a prescribed dose of 23.4 Gy were 47% (95% confidence interval [CI], 21%-69%), 44% (95% CI, 21%-65%), 41% (95% CI, 22%-60%), and 33% (95% CI, 23%-44%) with opposing fields, IMAT, IMRT, and IMPT, respectively. Neurogenic niche sparing during cranial irradiation of pediatric patients with MB is feasible and is estimated to lower the risks of long-term neurocognitive sequelae. Greatest sparing is achieved with intensity-modulated proton therapy, thus making this an attractive option to be tested in a prospective clinical trial.
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| 15. |
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| 16. |
- Brodin, Håkan, et al.
(författare)
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Fracture Mechanical Modelling of a Plasma Sprayed TBC System
- 2009
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Ingår i: Advanced Ceramic Coatings and Interfaces IV. - Westerville, OH, United States : American Ceramic Society Inc.. - 9780470457535 ; , s. 113-124
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Konferensbidrag (refereegranskat)abstract
- A thermal barrier coating (TBC) system subjected to thermal cycling will develop a microcrack partem near the interface between the metallic bond coat and the ceramic top coat. These small cracks link up and form internal TBC delaminations during repeated heating / cooling. After a longer time period, the internal delamination cracks will form a larger spallation damage, where the TBC is detached from the underlying material. Since cracks are initiated in multiple sites of the thermal barrier coating, the damage is initially considered to be governed by local stress conditions. The purpose of the present work is to compare experimental data with predictions of a physically based fatigue life model. The present study has been performed on plasma-sprayed TBCs where the interface geometry has been varied. In the present work, calculation of fatigue life is done for a number of cases under thermal fatigue loading. Different interface geometries are compared in order to understand the influence of variations in the TC/BC interface roughness on oxidation behaviour and thermal fatigue life. Thermal fatigue tests indicate that an increased surface roughness is beneficial from a fatigue life point of view.
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| 17. |
- Brodin, N Patrik, et al.
(författare)
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Hippocampal sparing radiotherapy for pediatric medulloblastoma: impact of treatment margins and treatment technique.
- 2014
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Ingår i: Neuro-oncology. - : Oxford University Press (OUP). - 1523-5866 .- 1522-8517. ; 16:4, s. 594-602
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundWe investigated how varying the treatment margin and applying hippocampal sparing and proton therapy impact the risk of neurocognitive impairment in pediatric medulloblastoma patients compared with current standard 3D conformal radiotherapy.MethodsWe included 17 pediatric medulloblastoma patients to represent the variability in tumor location relative to the hippocampal region. Treatment plans were generated using 3D conformal radiotherapy, hippocampal sparing intensity-modulated radiotherapy, and spot-scanned proton therapy, using 3 different treatment margins for the conformal tumor boost. Neurocognitive impairment risk was estimated based on dose-response models from pediatric CNS malignancy survivors and compared among different margins and treatment techniques.ResultsMean hippocampal dose and corresponding risk of cognitive impairment were decreased with decreasing treatment margins (P < .05). The largest risk reduction, however, was seen when applying hippocampal sparing proton therapy-the estimated risk of impaired task efficiency (95% confidence interval) was 92% (66%-98%), 81% (51%-95%), and 50% (30%-70%) for 3D conformal radiotherapy, intensity-modulated radiotherapy, and proton therapy, respectively, for the smallest boost margin and 98% (78%-100%), 90% (60%-98%), and 70% (39%-90%) if boosting the whole posterior fossa. Also, the distance between the closest point of the planning target volume and the center of the hippocampus can be used to predict mean hippocampal dose for a given treatment technique.ConclusionsWe estimate a considerable clinical benefit of hippocampal sparing radiotherapy. In choosing treatment margins, the tradeoff between margin size and risk of neurocognitive impairment quantified here should be considered.
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| 18. |
- Brodin, N. Patrik, et al.
(författare)
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Modeling freedom from progression for standard-risk medulloblastoma : A mathematical tumor control model with multiple modes of failure
- 2013
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Ingår i: International Journal of Radiation Oncology, Biology, Physics. - : Elsevier BV. - 0360-3016. ; 87:2, s. 422-429
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Tidskriftsartikel (refereegranskat)abstract
- Purpose As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data. Methods and Materials Outcome data for standard-risk MB published after 1990 with pattern of relapse information were used to fit a tumor control dose-response model addressing failures in both the high-dose boost volume and the elective craniospinal volume. Estimates of 5-year event-free survival from 2 large randomized MB trials were used to model the time-to-progression distribution. Uncertainty in freedom from progression (FFP) was estimated by Monte Carlo sampling over the statistical uncertainty in input data. Results The estimated 5-year FFP (95% confidence intervals [CI]) for craniospinal doses of 15, 18, 24, and 36 Gy while maintaining 54 Gy to the posterior fossa was 77% (95% CI, 70%-81%), 78% (95% CI, 73%-81%), 79% (95% CI, 76%-82%), and 80% (95% CI, 77%-84%) respectively. The uncertainty in FFP was considerably larger for craniospinal doses below 18 Gy, reflecting the lack of data in the lower dose range. Conclusions Estimates of tumor control and time-to-progression for standard-risk MB provides a data-driven setting for hypothesis generation or power calculations for prospective trials, taking the uncertainties into account. The presented methods can also be applied to incorporate further risk-stratification for example based on molecular biomarkers, when the necessary data become available.
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| 19. |
- Broström, Göran, et al.
(författare)
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Social class and sex-specific adult mortality during 200 years in Sweden
- 2019
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Konferensbidrag (refereegranskat)abstract
- Recent regional studies on adult mortality and socio-economic status inSweden are merged and also completed with analyses from country-widecensuses in strategic time periods, with the purpose to find out whetherthe locally drawn conclusions about a changing social gradient in mortalitystill holds.The answer is firmly positive: While the upper classes have definiteadvantage in modern time (after, say, the 1960s), the reverse situationholds during the nineteenth and early twentieth century for men. Women, onthe other hand, seem to follow the expected pattern of a positive socialgradient through the last 200 years.
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| 20. |
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| 21. |
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| 22. |
- Danared, Håkan, et al.
(författare)
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Preface
- 2017
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Ingår i: IPAC 2018 : Proceedings of the 8th International Particle Accelerator Conference - Proceedings of the 8th International Particle Accelerator Conference. - 9783954501823
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 23. |
- Di Francesco, Davide, et al.
(författare)
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Debottlenecking a Pulp Mill by Producing Biofuels from Black Liquor in Three Steps
- 2021
-
Ingår i: ChemSusChem. - : Wiley. - 1864-5631 .- 1864-564X. ; 14:11, s. 2414-2425
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Tidskriftsartikel (refereegranskat)abstract
- By extracting lignin, pulp production can be increased without heavy investments in a new recovery boiler, the typical bottleneck of a pulp mill. The extraction is performed by using 0.20 and 0.15 weight equivalents of CO2 and H2SO4 respectively. Herein, we describe lignin esterification with fatty acids using benign reagents to generate a lignin ester mixable with gas oils. The esterification is accomplished by activating the fatty acid and lignin with acetic anhydride which can be regenerated from the acetic acid recycled in this reaction. The resulting mass balance ratio is fatty acid/lignin/acetic acid (2 : 1 : 0.1). This lignin ester can be hydroprocessed to generate hydrocarbons in gasoline, aviation, and diesel range. A 300-hour continuous production of fuel was accomplished. By recirculating reagents from both the esterification step and applying a water gas shift reaction on off-gases from the hydroprocessing, a favorable overall mass balance is realized.
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| 24. |
- Domènech-Gil, Guillem, Mr. Doctor, et al.
(författare)
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Electronic Nose for Improved Environmental Methane Monitoring
- 2024
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Ingår i: Environmental Science and Technology. - : AMER CHEMICAL SOC. - 0013-936X .- 1520-5851. ; 58, s. 352-361
-
Tidskriftsartikel (refereegranskat)abstract
- Reducing emissions of the key greenhouse gas methane (CH4) is increasingly highlighted as being important to mitigate climate change. Effective emission reductions require cost-effective ways to measure CH4 to detect sources and verify that mitigation efforts work. We present here a novel approach to measure methane at atmospheric concentrations by means of a low-cost electronic nose strategy where the readings of a few sensors are combined, leading to errors down to 33 ppb and coefficients of determination, R-2, up to 0.91 for in situ measurements. Data from methane, temperature, humidity, and atmospheric pressure sensors were used in customized machine learning models to account for environmental cross-effects and quantify methane in the ppm-ppb range both in indoor and outdoor conditions. The electronic nose strategy was confirmed to be versatile with improved accuracy when more reference data were supplied to the quantification model. Our results pave the way toward the use of networks of low-cost sensor systems for the monitoring of greenhouse gases.
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| 25. |
- Edsfeldt, Andreas, et al.
(författare)
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Human Atherosclerotic Plaque Progression Is Dependent on Apoptosis According to Bomb-Pulse 14C Dating
- 2021
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Ingår i: JACC: Basic to Translational Science. - : Elsevier BV. - 2452-302X. ; 6:9-10, s. 734-745
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Tidskriftsartikel (refereegranskat)abstract
- Individuals with rapidly progressing atherosclerotic plaques are at higher risk of experiencing acute complications. Currently, we lack knowledge regarding factors in human plaque that cause rapid progression. Using the 14C bomb-pulse dating method, we assessed the physical age of atherosclerotic plaques and which biological processes were associated with rapidly progressing plaques. Interestingly, increased apoptosis was the main component associated with a young physical plaque age, reflecting rapid plaque progression. Our findings in combination with recent advances in imaging techniques could guide future diagnostic imaging strategies to identify rapidly progressing plaques or therapeutic targets, halting plaque progression.
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| 26. |
- Eriksson, Anna, et al.
(författare)
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Epigenetic aberrations in acute myeloid leukemia : Early key events during leukemogenesis
- 2015
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Ingår i: Experimental Hematology. - : Elsevier BV. - 0301-472X .- 1873-2399. ; 43:8, s. 609-624
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Tidskriftsartikel (refereegranskat)abstract
- As a result of the introduction of new sequencing technologies, the molecular landscape of acute myeloid leukemia (AML) is rapidly evolving. From karyotyping, which detects only large genomic aberrations of metaphase chromosomes, we have moved into an era when sequencing of each base pair allows us to define the AML genome at highest resolution. This has revealed a new complex landscape of genetic aberrations where addition of mutations in epigenetic regulators has been one of the most important contributions to the understanding of the pathogenesis of AML. These findings, together with new insights into epigenetic mechanisms, have placed dysregulated epigenetic mechanisms at the forefront of AML development. Not only have several new mutations in genes directly involved in epigenetic regulatory mechanisms been discovered, but also previously well-known gene fusions have been found to exert aberrant effects through epigenetic mechanisms. In addition, mutations in epigenetic regulators such as DNMT3A, TET2, and ASXL1 have recently been found to be the earliest known events during AML evolution and to be present as preleukemic lesions before the onset of AML. In this article, we review epigenetic changes in AML also in relation to what is known about their mechanism of action and their prognostic role.
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| 27. |
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| 28. |
- Eriksson, Annika, et al.
(författare)
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The Need to Document
- 2005
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Bok (övrigt vetenskapligt/konstnärligt)
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| 29. |
- Eriksson, Daniel, 1987-
(författare)
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Getting to grips with cartons : Interactions of carbonboard packages with an artificial finger
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Packaging is an important part of most products in our modern world. It produces waste, but it also enables products to reach consumers safely and efficiently. Hence, the proper design of packaging is becoming increasingly important. Historically, cartonboard packages were designed for box compression strength. While this remains important, there are other types of loads that are important to consider. One such type of load arises from manual handling. As packages as moved and used, consumers need to exert forces on the package. These forces deform and can damage the package.Understanding these interactions can be challenging. By developing a method for quantifying the deformation due to manual handling, it becomes possible to measure and compare a redesigned package with the original to see if the performance has changed. This can aid packaging designers, but it can also be used for product control. The converting process is complex and deviations from specification can be introduced at many points along the production process.In this work, a method for quantifying interactions similar to those in manual handling is presented and evaluated. The method is then applied to study the effect of position and material properties on the mechanics of the interaction. The method is shown to have low variability and be robust to modifications in packaging and experimental design. It was seen that increasing the size of packages from 82 mm to 98 mm corresponded to decreasing the grammage by 10-20%. The method also showed the stiffening effect of corners and flaps, suggesting that the strategic placement of these design elements could help maintain the desired mechanical properties of the package at the point of interaction, provided the most likely point can be predicted.
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| 30. |
- Eriksson, Elisabet, 1971-, et al.
(författare)
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Internationally educated nurses' and medical graduates' experiences of getting a license and practicing in Sweden - a qualitative interview study
- 2018
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Ingår i: BMC Medical Education. - : Springer Science and Business Media LLC. - 1472-6920. ; 18:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The Swedish healthcare system has an increased need for nurses and physicians, and the number of International Educated Nurses (IENs) and International Medical Graduates (IMGs) seeking job opportunities and a license to practice in Sweden is rising. This study explored how IENs and IMGs describe their experience of getting a license to practice, their perceptions of working in Sweden and of how their intercultural competence is utilized.METHOD: A qualitative study based on semi-structured interviews with 11 IENs and 11 IMGs. The interviews were conducted between 2015 and 2017. The data were analyzed using qualitative content analysis.RESULTS: Three main themes were identified: 'Getting a license - a different story,' 'The work is familiar, yet a lot is new,' 'Trying to master a new language.' The time to obtain a license to practice and finding a job was shorter for IENs and IMGs coming from European countries than for those from non-European countries. Some of the experiences of getting a license to practice and of entering a new workplace in another country were the same for nurses and physicians. In general, both IENs and IMGs felt welcomed and used their intercultural competence at work. Lack of language skills was regarded as the main problem for both professions, while workplace introduction was shorter for IMGs than for IENs.CONCLUSIONS: Problems related to language and culture are often underestimated, therefore organizations and managers employing IENs and IMGs should provide longer workplace introduction to facilitate the acculturation process. More time-efficient language courses specifically adapted to IENs and IMGs could make the transition easier and shorten the time to obtain a license to practice for both professions.
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| 31. |
- Eriksson, Johan, 1969-
(författare)
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Heidegger och filosofins metod : Om den filosofiska artikulationens och den filosofiska insiktens karaktär eller En introduktion till fenomenologin
- 2007
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Phenomenology is a philosophical method created by Edmund Husserl at the beginning of the last century. In general terms, phenomenology is a way of investigating meaning, where ”meaning” is the most formal concept describing the way the world (with its different kind of objects) is given in every kind of experience.The most influential development and modification of Husserl’s phenomenology is to be found in the works of his disciple Martin Heidegger. In Heidegger’s magnum opus Sein und Zeit we can read that philosophy in its most original sense is ontology, and ontology is only possible in the form of phenomenology.Heidegger, however, never gave a systematic and explicit account of the phenomenological method of ontology. The ambition of this study is to read the ontological investigation of the being of man (or the being of ”Dasein”) which Heidegger develops in Sein und Zeit, as an investigation which ultimate purpose is to give ontology its own methodological self-consciousness. More specifically, on the basis of Heidegger’s investigations into Dasein’s being, together with the explicit methodological discussions which can be found both in Sein und Zeit and in the lecture-courses Heidegger gave before and around the time of that work, the ambition of this study is to try to reconstruct and unfold a systematic analysis of Heidegger’s phenomenological method. This analysis is thus centered around questions such as: Given the fact that the philosophical research does not seek knowledge about something which can be found anywhere in the world, how does philosophy gain access to its own thematic ”object”? How does philosophy ground and prove? What characterizes philosophical knowledge? And most importantly: what characterizes that peculiar form of articulation and conceptuality which in a genuine way tries to mediate and generate knowledge about something which ”is” not?
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| 32. |
- Eriksson, Kristina, 1962, et al.
(författare)
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Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2-Induced IFN-β Expression.
- 2017
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Ingår i: Journal of immunology (Baltimore, Md. : 1950). - : The American Association of Immunologists. - 1550-6606 .- 0022-1767. ; 199:8, s. 2613-2617
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Tidskriftsartikel (refereegranskat)abstract
- IFN-γ-inducible protein 16 (IFI16) is an immunological DNA sensor proposed to act in the cyclic GMP-AMP synthase-stimulator of IFN genes pathway. Because mice do not have a clear ortholog of IFI16, this system is not suitable for genetic studies of IFI16. In this study, we have compared the dependency on IFI16, cyclic GMP-AMP synthase, and stimulator of IFN genes for type I IFN induction by a panel of pathogenic bacteria and DNA viruses. The IFN response induced by HSV-2 was particularly dependent on IFI16. In a cohort of patients with genital herpes and healthy controls, the minor G allele of the IFI16 single nucleotide polymorphism rs2276404 was associated with resistance to infection. Furthermore, the combination of this allele with the C allele of rs1417806 was significantly overrepresented in uninfected individuals. Cells from individuals with the protective GC haplotype expressed higher levels of IFI16 and induced more IFN-β upon HSV-2 infection. These data provide genetic evidence for a role for IFI16 in protection against genital herpes.
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| 33. |
- Eriksson, Maertha, et al.
(författare)
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Insect brain plasticity : effects of olfactory input on neuropil size
- 2019
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Ingår i: Royal Society Open Science. - : The Royal Society. - 2054-5703. ; 6:8
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Tidskriftsartikel (refereegranskat)abstract
- Insect brains are known to express a high degree of experience-dependent structural plasticity. One brain structure in particular, the mushroom body (MB), has been attended to in numerous studies as it is implicated in complex cognitive processes such as olfactory learning and memory. It is, however, poorly understood to what extent sensory input per se affects the plasticity of the mushroom bodies. By performing unilateral blocking of olfactory input on immobilized butterflies, we were able to measure the effect of passive sensory input on the volumes of antennal lobes (ALs) and MB calyces. We showed that the primary and secondary olfactory neuropils respond in different ways to olfactory input. ALs show absolute experience-dependency and increase in volume only if receiving direct olfactory input from ipsilateral antennae, while MB calyx volumes were unaffected by the treatment and instead show absolute age-dependency in this regard. We therefore propose that cognitive processes related to behavioural expressions are needed in order for the calyx to show experience-dependent volumetric expansions. Our results indicate that such experience-dependent volumetric expansions of calyces observed in other studies may have been caused by cognitive processes rather than by sensory input, bringing some causative clarity to a complex neural phenomenon.
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| 34. |
- Eriksson, Maertha, et al.
(författare)
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Structural plasticity of olfactory neuropils in relation to insect diapause
- 2020
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Ingår i: Ecology and Evolution. - : Wiley. - 2045-7758. ; 10:24, s. 14423-14434
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Tidskriftsartikel (refereegranskat)abstract
- Many insects that live in temperate zones spend the cold season in a state of dormancy, referred to as diapause. As the insect must rely on resources that were gathered before entering diapause, keeping a low metabolic rate is of utmost importance. Organs that are metabolically expensive to maintain, such as the brain, can therefore become a liability to survival if they are too large. Insects that go through diapause as adults generally do so before entering the season of reproduction. This order of events introduces a conflict between maintaining low metabolism during dormancy and emerging afterward with highly developed sensory systems that improve fitness during the mating season. We investigated the timing of when investments into the olfactory system are made by measuring the volumes of primary and secondary olfactory neuropils in the brain as they fluctuate in size throughout the extended diapause life-period of adult Polygonia c-album butterflies. Relative volumes of both olfactory neuropils increase significantly during early adult development, indicating the importance of olfaction to this species, but still remain considerably smaller than those of nondiapausing conspecifics. However, despite butterflies being kept under the same conditions as before the dormancy, their olfactory neuropil volumes decreased significantly during the postdormancy period. The opposing directions of change in relative neuropil volumes before and after diapause dormancy indicate that the investment strategies governing structural plasticity during the two life stages could be functionally distinct. As butterflies were kept in stimulus-poor conditions, we find it likely that investments into these brain regions rely on experience-expectant processes before diapause and experience-dependent processes after diapause conditions are broken. As the shift in investment strategies coincides with a hard shift from premating season to mating season, we argue that these developmental characteristics could be adaptations that mitigate the trade-off between dormancy survival and reproductive fitness.
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| 35. |
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| 36. |
- Eriksson, Robert, et al.
(författare)
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TBC bond coat-top coat interface roughness : influence on fatigue life and modelling aspects
- 2013
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Ingår i: Surface & Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 236, s. 230-238
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Tidskriftsartikel (refereegranskat)abstract
- Thermal barrier coatings (TBCs), when used in gas turbines, may fail through thermal fatigue, causing the ceramic top coat to spall off the metallic bond coat. The life prediction of TBCs often involves finite element modelling of the stress field close to the bond coat/top coat interface and thus relies on accurate modelling of the interface. The present research studies the influence of bond coat/top coat interface roughness on the thermal fatigue life of plasma sprayed TBCs. By using different spraying parameters, specimens with varying interface roughness were obtained. During thermal cycling it was found that higher interface roughness promoted longer thermal fatigue life. The interfaces were characterised by roughness parameters, such as Ra, Rq and Rq, as well as by autocorrelation, material ratio curves, probability plots and slope distribution. The variation of spray parameters was found to affect amplitude parameters, such as Ra, but not spacing parameters, such as RSm. Three different interface geometries were tried for finite element crack growth simulation: cosine, ellipse and triangular shape. The cosine model was found to be an appropriate interface model and a procedure for obtaining the necessary parameters, amplitude and wavelength, was suggested. The positive effect of high roughness on life was suggested to be due to a shift from predominantly interface failure, for low roughness, to predominantly top coat failure, for high roughness.
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| 37. |
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| 38. |
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| 39. |
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| 40. |
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| 41. |
- Eriksson, Sören, 1953-
(författare)
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Can Singapore develop into a global media city?
- 2011. - 1st
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Ingår i: Media Clusters. - Cheltenham, UK, Northampton, MA, USA : Edward Elgar Publishing. - 978 0 85793 268 6 ; , s. 328-353
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Bokkapitel (refereegranskat)
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| 42. |
- Eriksson, Sören, 1953-
(författare)
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China's aircraft industry: collaboration and technology transfer - the case of Airbus
- 2010
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Ingår i: International Journal of Technology Transfer and Commercialisation (IJTTC). - : Inderscience Enterprises Ltd. - 1470-6075 .- 1741-5284. ; 9:4, s. 306-325
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Tidskriftsartikel (refereegranskat)abstract
- China has moved a long way in economic and industrial development during the last decades and has developed into a global player in many industries. With increased knowledge in high-technology industries, China has ambitions to move into sectors that necessitate a high level of research and development, such as the aerospace industry. China is now in the process of establishing a modern aircraft industry based on domestic efforts as well as agreements with foreign partners in the manufacturing of complete aircraft. This paper analyzes what measures have been taken by Airbus in the form of technology transfer and other supportive measures to strengthen its position in the Chinese market. The findings conclude that Airbus’ transfer should be looked upon as a broad spectrum of technology and knowledge transfer, which include aircraft manufacturing technology, as well as cabin crew training centre, establishment of a warehouse and suppliers ”village”, an engineering centre, maintenance and various service functions.
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| 43. |
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| 44. |
- Eriksson, Sören
(författare)
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Cluster creation and innovation within an emerging Taiwanese high-tech sector
- 2006
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Ingår i: International Journal of Technology Transfer and Commercialisation. - 1470-6075 .- 1741-5284. ; 5:3, s. 208-236
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Tidskriftsartikel (refereegranskat)abstract
- The paper investigates in what way and to what extent Taiwan has been able to develop a commercial aerospace industry and the formation of an internationally competitive supplier system, i.e. high-tech cluster. The development of such an industry has been much more difficult than expected. Since the late 1990s there have been signs that a supplier system is under development, but there are great challenges ahead, amid a fierce international competition.
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| 45. |
- Eriksson, Sören, 1953-
(författare)
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Clusters : A Survey of Research within Localized Economic Growth
- 2009
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This paper explores the nature and development of research in localized growth, focusing on the development of economic and industrial clusters. The renewed interest in agglomeration and localized economic growth research has come from a variety of disciplines, but ideas and thoughts about local thickening have a much older origin. Research in local agglomeration and embeddedness crosses through expressions such as cluster, industrial districts, innovative milieu and networks. ‘Internal’ versus ‘external’ influences, weaknesses of research, definitions and new approaches of research in clusters are also discussed. Not all spatial agglomerations of firms in the same or related sectors necessarily comprise a cluster.
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| 46. |
- Eriksson, Sören, et al.
(författare)
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Commercial air transport in Africa : changing structure and development of country pairs
- 2024
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Ingår i: International Journal of Services, Technology and Management. - 1460-6720. ; 29:1, s. 59-75
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Tidskriftsartikel (refereegranskat)abstract
- This study investigates cross-border commercial air passenger traffic in Africa, focusing on the development of the 15 busiest country pairs during the period 1989 to 2015. It explores dimensions not previously studied by using ICAO’s ‘Traffic by Flight Stage’ (TFS) and data from the CEPII Gravity Dataset. The spatial results show on an uneven geographical distribution of country pairs with the centre of gravity to South, East and North-East Africa, with one long-distance corridor between Egypt and South Africa. Countries in North and West Africa have rather few linkages, except for Egypt. Central African countries are not represented among the 15 country pairs. Although the number of passengers and the rank among the countries have shifted, South Africa and Egypt stand out, as having most country pair connections. Factors such as changing economic, diplomatic and political relations have had an influence on changing country pair connections throughout the period. A number of variables were selected to investigate how they correlated with Africa’s commercial passenger traffic. Of the seven variables selected, five did show on a correlation and two did partly so. In that view, Africa’s air traffic follows rather typical patterns.
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| 47. |
- Eriksson, Sören, 1953-
(författare)
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Development of a conceptual model for an integrated logistics cluster: a case of Jönköping, Sweden
- 2009
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Ingår i: International Journal of Logistics Economics and Globalisation. - : Inderscience. - 1741-5373 .- 1741-5381. ; Vol. 2:No. 1, s. 77-94
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Tidskriftsartikel (refereegranskat)abstract
- The profound changes in the world economy in the last few decades accompanied by the duality of de-territorialising and territorialising forces has seen an increased interest in localised growth in the spatial economy. This pilot study deals with identifying an emerging logistics cluster in Jönköping, Sweden, by using qualitative and quantitative measures. Based on these findings a conceptual model is developed which can be a basis for further studies of logistics clusters. There is a need for further research on such clusters, especially their role in a global-local context as well as from supply-chain perspectives.
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| 48. |
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| 49. |
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| 50. |
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