| 1. |
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| 2. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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| 4. |
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| 6. |
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| 7. |
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| 8. |
- Drake, TM, et al.
(författare)
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Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
- 2020
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Ingår i: BMJ global health. - : BMJ. - 2059-7908. ; 5:12
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Tidskriftsartikel (refereegranskat)abstract
- Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings.MethodsA multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI).ResultsOf 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI.ConclusionThe odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
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| 9. |
- Sumaila, U. Rashid, et al.
(författare)
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WTO must ban harmful fisheries subsidies
- 2021
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 374:6567, s. 544-544
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Ademuyiwa, Adesoji O., et al.
(författare)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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Ingår i: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Tidskriftsartikel (refereegranskat)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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| 11. |
- Hagag, Naglaa M., et al.
(författare)
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Isolation of a Novel Reassortant Highly Pathogenic Avian Influenza (H5N2) Virus in Egypt
- 2019
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Ingår i: Viruses. - : MDPI. - 1999-4915. ; 11:6
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Tidskriftsartikel (refereegranskat)abstract
- Highly pathogenic avian influenza (HPAI) H5N1 and H5N8 have become endemic among domestic poultry in Egypt since 2006 and 2016, respectively. In parallel, the low pathogenic avian influenza H9N2 virus has been endemic since 2010. Despite the continuous circulation of these subtypes for several years, no natural reassortant has been detected so far among the domestic poultry population in Egypt. In this study, the HPAI (H5N2) virus was isolated from a commercial duck farm, giving evidence of the emergence of the first natural reassortment event in domestic poultry in Egypt. The virus was derived as a result of genetic reassortment between avian influenza viruses of H5N8 and H9N2 subtypes circulating in Egypt. The exchange of the neuraminidase segment and high number of acquired mutations might be associated with an alteration in the biological propensities of this virus.
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| 12. |
- Hassan, Ayah M., et al.
(författare)
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Molecular detection, phylogenetic analysis and genetic diversity of recently isolated foot-and-mouth disease virus serotype A African topotype, Genotype IV
- 2022
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Ingår i: Virology Journal. - : BioMed Central (BMC). - 1743-422X. ; 19:1
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundSurveillance for circulating emerging diseases of economic importance has a major role in the rapid response to major pathogen outbreaks. Foot-and-mouth disease virus (FMDV) is one of the significant endemic viruses in Egypt. FMDV is periodically investigated for monitoring evolution and emergence of new variants. The genetic characterization of foot-and-mouth disease (FMD) virus serotype A responsible for recent outbreaks of FMD in Egypt was determined.MethodsSamples were collected from different locations and virus isolation was performed using BHK-21 cells. Viral RNA was extracted and samples were screened for FMDV using real-time RT-PCR. DNA sequence analysis was performed and computational and bioinformatics analyses were used to determine the substitution rates and phylogenetic relationship.ResultsSequence and phylogenetic analyses of full-length 1D region of FMDV samples collected from different governorates in 2020 showed close similarity to Egyptian FMDV strains from serotype A-African topotype-G-IV with genetic variation of 6.5%. Recently isolated FMDV strains showed high genetic variations from locally used vaccine strains in the major antigenic sites of VP1 region.ConclusionsAlthough, efforts made by the veterinary authorities to implement an effective mass vaccination plan, the recently detected FMDV strains in this study could not be subtyped using the FMDV primers routinely used for molecular serotyping. These dissimilarities raise the alarm for reconsideration of the FMDV isolates used in vaccine manufacture. Clearly close monitoring of FMD in Egypt is urgently required to define the risks of future outbreaks and to ensure appropriate control measures against FMD major outbreaks.
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| 13. |
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| 14. |
- Avall, Karin, et al.
(författare)
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Apolipoprotein CIII links islet insulin resistance to beta-cell failure in diabetes
- 2015
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 112:20, s. E2611-E2619
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Tidskriftsartikel (refereegranskat)abstract
- Insulin resistance and beta-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insulin resistance but also with cardiovascular disorders and inflammation. We now demonstrate that local apoCIII production is connected to pancreatic islet insulin resistance and beta-cell failure. An increase in islet apoCIII causes promotion of a local inflammatory milieu, increased mitochondrial metabolism, deranged regulation of beta-cell cytoplasmic free Ca2+ concentration ([Ca2+](i)) and apoptosis. Decreasing apoCIII in vivo results in improved glucose tolerance, and pancreatic apoCIII knockout islets transplanted into diabetic mice, with high systemic levels of the apolipoprotein, demonstrate a normal [Ca2+](i) response pattern and no hallmarks of inflammation. Hence, under conditions of islet insulin resistance, locally produced apoCIII is an important diabetogenic factor involved in impairment of beta-cell function and may thus constitute a novel target for the treatment of type 2 diabetes mellitus.
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| 15. |
- Essam, Tamer, et al.
(författare)
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Biological treatment of industrial wastes in a photobioreactor
- 2006
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Ingår i: Water Science and Technology. - : IWA Publishing. - 0273-1223 .- 1996-9732. ; 53:11, s. 117-125
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Tidskriftsartikel (refereegranskat)abstract
- An algal-bacterial consortium was tested for the treatment from a coke factory. A Chlorella vulgaris strain and a phenol-degrading Alcaligenes sp. were first isolated from the wastewater treatment plant to serve as inocula in the subsequent biodegradation tests. Batch tests were then conducted with samples from the real wastewater or using a synthetic wastewater containing 325 mg phenol/l and 500 mg NH4+/l as target pollutants. Direct biological treatment of-the real wastewater was not possible due to the toxicity of organic compounds. Activated carbon adsorption and UV(A-B)-irradiation were efficient in detoxifying the effluent for subsequent biological treatment as inoculation of pretreated samples with the algal-bacterial consortium was followed by complete phenol removal and NH4+ removal of 45%. Complete phenol removal and 33% NH4+ removal were achieved during the fed-batch treatment of artificial wastewater. at 6 d hydraulic retention time (HRT). Under continuous feeding at 3.6 d HRT, phenol and NH4+ removal dropped to 58 and 18%, respectively. However, complete phenol removal and 29% NH4+ removal were achieved when 8 g NaHCO3/1 was added to the artificial wastewater to enhance algal growth. This study confirms the potential of solar-based industrial wastewater treatment based on solar-based UV pretreatment followed by algal-bacterial biodegradation.
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| 16. |
- Goel, Ashutosh, et al.
(författare)
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Structure and crystallization behaviour of some MgSiO3-based glasses
- 2009
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Ingår i: Ceramics International. - : Elsevier BV. - 0272-8842. ; 35:4, s. 1529-1538
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Tidskriftsartikel (refereegranskat)abstract
- We report on the structure and crystallization behaviour of four enstatite based glasses. Two glasses with nominal compositions of Y0.125Mg0.875Si0.875B0.125O3 and Y0.125Mg0.725Ba0.15Si0.875B0.125O3 were prepared as parent glasses while the other two glasses were derived by the addition of 8 wt.% Al2O3 to the parent glass compositions, respectively. Structural features of the glasses were accessed by Fourier transform infrared spectroscopy (FTIR). Non-isothermal crystallization kinetics and thermal stability of Al2O3-free glasses were studied using differential scanning calorimetry (DSC). It has been shown that these glasses exhibit higher activation energy of viscous flow and are prone to surface crystallization. Activation energy of crystallization decreases with the addition of BaO in the glasses. Crystallization behaviour of all the experimental glasses in the temperature range of 800–1000 °C was followed by X-ray diffraction (XRD) and FTIR. Clinoenstatite and orthoenstatite were the major crystalline phases in the BaO-free glass-ceramics while BaO-containing compositions featured the early formation and stabilization of protoenstatite.
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| 17. |
- Holmberg, Rebecka, et al.
(författare)
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Lowering apolipoprotein CIII delays onset of type 1 diabetes
- 2011
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 108:26, s. 10685-10689
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Tidskriftsartikel (refereegranskat)abstract
- Serum levels of apolipoprotein CIII (apoCIII) are increased in type 1 diabetic patients, and when β cells are exposed to these diabetic sera, apoptosis occurs, an effect abolished by an antibody against apoCIII. We have investigated the BB rat, an animal model that develops a human-like type 1 diabetes, and found that apoCIII was also increased in sera from prediabetic rats. This increase in apoCIII promoted β-cell death. The endogenous levels of apoCIII were reduced by treating prediabetic animals with an antisense against this apolipoprotein, resulting in a significantly delayed onset of diabetes. ApoCIII thus serves as a diabetogenic factor, and intervention with this apolipoprotein in the prediabetic state can arrest disease progression. These findings suggest apoCIII as a target for the treatment of type 1 diabetes.
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| 18. |
- Jung, Ivar, 1952-, et al.
(författare)
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Colour Associations in Different Cultures
- 2018
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Ingår i: Proceedings of the International Colour Association (AIC) Conference 2018. - Newtown : The International Colour Association. - 9780648472407 ; , s. 503-508
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Konferensbidrag (refereegranskat)abstract
- The aim of this study is to investigate if there are colours that are associated with certain words. The study was conducted in nine countries (Germany, Iran, Japan, Nepal, Russia, Saudi Arabia, Sweden, Turkey and Uganda) to see if there are cultural differences in the way people associate colours with the words. The subjects were asked to match each of the words with only one colour. They could choose colours from the chart consisting of 27 colour samples selected from the NCS Atlas. In total, the dataset included 18,072 responses from 753 participants. The collected data were analysed by hue, chromaticness and the degree of blackness and whiteness. The results show that the colour associations with the words vary to different extent between the different countries. That indicates that there are universal associations with colours for some of the words, as well as cultural differences.
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| 19. |
- Mostafa, Reham R., et al.
(författare)
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An enhanced chameleon swarm algorithm for global optimization and multi-level thresholding medical image segmentation
- 2024
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Ingår i: Neural Computing & Applications. - : SPRINGER LONDON LTD. - 0941-0643 .- 1433-3058.
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Tidskriftsartikel (refereegranskat)abstract
- Medical image segmentation is crucial in using digital images for disease diagnosis, particularly in post-processing tasks such as analysis and disease identification. Segmentation of magnetic resonance imaging (MRI) and computed tomography images pose distinctive challenges attributed to factors such as inadequate illumination during the image acquisition process. Multilevel thresholding is a widely adopted method for image segmentation due to its effectiveness and ease of implementation. However, the primary challenge lies in selecting the optimal set of thresholds to achieve accurate segmentation. While Otsu's between-class variance and Kapur's entropy assist in identifying optimal thresholds, their application to cases requiring more than two thresholds can be computationally intensive. Meta-heuristic algorithms are commonly employed in literature to calculate the threshold values; however, they have limitations such as a lack of precise convergence and a tendency to become stuck in local optimum solutions. In this paper, we introduce an improved chameleon swarm algorithm (ICSA) to address these limitations. ICSA is designed for image segmentation and global optimization tasks, aiming to improve the precision and efficiency of threshold selection in medical image segmentation. ICSA introduces the concept of the "best random mutation strategy" to enhance the search capabilities of the standard chameleon swarm algorithm (CSA). This strategy leverages three distribution functions-Levy, Gaussian, and Cauchy-for mutating search individuals. These diverse distributions contribute to improved solution quality and help prevent premature convergence. We conduct comprehensive experiments using the IEEE CEC'20 complex optimization benchmark test suite to evaluate ICSA's performance. Additionally, we employ ICSA in image segmentation, utilizing Otsu's approach and Kapur's entropy as fitness functions to determine optimal threshold values for a set of MRI images. Comparative analysis reveals that ICSA outperforms well-known metaheuristic algorithms when applied to the CEC'20 test suite and significantly improves image segmentation performance, proving its ability to avoid local optima and overcome the original algorithm's drawbacks. Medical image segmentation is essential for employing digital images for disease diagnosis, particularly for post-processing activities such as analysis and disease identification. Due to poor illumination and other acquisition-related difficulties, radiologists are especially concerned about the optimal segmentation of brain magnetic resonance imaging (MRI). Multilevel thresholding is the most widely used image segmentation method due to its efficacy and simplicity of implementation. The issue, however, is selecting the optimum set of criteria to effectively segment each image. Although methods like Otsu's between-class variance and Kapur's entropy help locate the optimal thresholds, using them for more than two thresholds requires a significant amount of processing resources. Meta-heuristic algorithms are commonly employed in literature to calculate the threshold values; however, they have limitations such as a lack of precise convergence and a tendency to become stuck in local optimum solutions. Due to the aforementioned, we present an improved chameleon swarm algorithm (ICSA) in this paper for image segmentation and global optimization tasks to be able to address these weaknesses. In the ICSA method, the best random mutation strategy has been introduced to improve the searchability of the standard CSA. The best random strategy utilizes three different types of distribution: Levy, Gaussian, and Cauchy to mutate the search individuals. These distributions have different functions, which help enhance the quality of the solutions and avoid premature convergence. Using the IEEE CEC'20 test suite as a recent complex optimization benchmark, a comprehensive set of experiments is carried out in order to evaluate the ICSA method and demonstrate the impact of combining the best random mutation strategy with the original CSA in improving both the performance of the solutions and the rate at which they converge. Furthermore, utilizing the Otsu approach and Kapur's entropy as a fitness function, ICSA is used as an image segmentation method to select the ideal threshold values for segmenting a set of MRI images. Within the experiments, the ICSA findings are compared with well-known metaheuristic algorithms. The comparative findings showed that ICSA performs better than other competitors in solving the CEC'20 test suite and has a significant performance boost in image segmentation.
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| 20. |
- Paetzold, Martin, et al.
(författare)
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Rosetta Radio Science Investigations (RSI)
- 2007
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Ingår i: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 128:1-4, s. 599-627
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Forskningsöversikt (refereegranskat)abstract
- The Rosetta spacecraft has been successfully launched on 2nd March 2004 to its new target comet 67 P/Churyurnov-Gerasimenko. The science objectives of the Rosetta Radio Science Investigations (RSI) experiment address fundamental aspects of cometary physics such as the mass and bulk density of the nucleus, its gravity field, its interplanetary orbit perturbed by nongravitational forces, its size and shape, its internal structure, the composition and roughness of the nucleus surface, the abundance of large dust grains, the plasma content in the coma and the combined dust and gas mass flux. The masses of two asteroids, Steins and Lutetia, shall be determined during flybys in 2008 and 2010. respectively. Secondary objectives are the radio sounding of the solar corona during the superior conjunctions of the spacecraft with the Sun during the cruise phase. The radio carrier links of the spacecraft Telemetry, Tracking and Command (TT&C) subsystem between the orbiter and the Earth will be used for these investigations. An Ultrastable oscillator (USO) connected to both transponders of the radio subsystem serves as a stable frequency reference source for both radio downlinks at X-band (8.4 GHz) and S-band (2.3 GHz) in the one-way mode. The Simultaneous and coherent dual-frequency downlinks via the High Gain Antenna (HGA) permit separation of contributions from the classical Doppler shift and the dispersive media effects caused by the motion of the spacecraft with respect to the Earth and the propagation of the signals through the dispersive media, respectively.
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| 21. |
- Partiyan, Arthur, et al.
(författare)
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Fracture resistance of three-unit zirconia fixed partial denture with modified framework
- 2017
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Ingår i: Odontology. - : Springer. - 1618-1247 .- 1618-1255. ; 105:1, s. 62-67
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Tidskriftsartikel (refereegranskat)abstract
- Obtaining ideal prosthetic framework design is at times hindered by anatomical limitations in the posterior region that might increase the risk for zirconia restoration fracture. Modification such as increasing the bulk thickness especially in the connector region could result in strengthening the zirconia framework. Three-unit zirconia fixed partial dentures replacing mandibular molars were fabricated using the following two techniques: CAD/CAM technology and manual copy milling. Modified framework with unveneered full thickness connectors were designed and fabricated with the aforementioned methods. Conventional frameworks (0.5 mm thick with rounded 3 mm connectors) served as control (N = 20). After cementation on epoxy dies, the frameworks were loaded to fracture in a universal testing machine. Fractured surfaces were prepared for examination using scanning electron microscopy. Statistical analysis revealed significant differences in fracture resistance between conventional and modified framework design for both fabrication techniques tested. SEM examination indicated that critical crack originated at the tensile surface of the connectors for conventional frameworks. The critical crack for modified frameworks occurred on the axial wall of the abutments. The modification of the zirconia framework design presented significant improvement of the fracture resistance compared to the conventional design.
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| 22. |
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| 23. |
- Tanaka, Masaomi, et al.
(författare)
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DISCOVERY OF DRAMATIC OPTICAL VARIABILITY IN SDSS J1100+4421 : A PECULIAR RADIO-LOUD NARROW-LINE SEYFERT 1 GALAXY?
- 2014
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Ingår i: Astrophysical Journal Letters. - 2041-8205 .- 2041-8213. ; 793:2, s. L26-
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Tidskriftsartikel (refereegranskat)abstract
- We present our discovery of dramatic variability in SDSS J1100+4421 by the high-cadence transient survey Kiso Supernova Survey. The source brightened in the optical by at least a factor of three within about half a day. Spectroscopic observations suggest that this object is likely a narrow-line Seyfert 1 galaxy (NLS1) at z = 0.840, however, with unusually strong narrow emission lines. The estimated black hole mass of similar to 10(7) M-circle dot implies bolometric nuclear luminosity close to the Eddington limit. SDSS J1100+4421 is also extremely radio-loud, with a radio loudness parameter of R similar or equal to 4 x 10(2)-3 x 10(3), which implies the presence of relativistic jets. Rapid and large-amplitude optical variability of the target, reminiscent of that found in a few radio- and gamma-ray-loud NLS1s, is therefore produced most likely in a blazar-like core. The 1.4 GHz radio image of the source shows an extended structure with a linear size of about 100 kpc. If SDSS J1100+4421 is a genuine NLS1, as suggested here, this radio structure would then be the largest ever discovered in this type of active galaxies.
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| 24. |
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| 25. |
- Özkılıç, Yasin Onuralp, et al.
(författare)
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Influence of ceramic waste powder on shear performance of environmentally friendly reinforced concrete beams
- 2024
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Ingår i: Scientific Reports. - : Springer. - 2045-2322. ; 14
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Tidskriftsartikel (refereegranskat)abstract
- This investigation considered the usability of ceramic waste powder (CWP) in altered quantities in reinforced concrete beams (RCBs). In this way, it was aimed to reduce the environmental impacts of concrete by using CWP as a raw material in RCBs. 12 small-scale shear RCBs with the dimensions of 100 × 150 × 1000 mm were tested in this study. The variations of stirrups spacing and CWP ratio were examined in these specimens. The percentages of CWP by weight utilized in RCBs were 10%, 20%, and 30%, and stirrups spacings were adopted as 270 mm, 200 mm, and 160 mm. At the end of the study, it was determined that more than 10% CWP additive negatively affected the RCBs’ compressive strength. The load-carrying capacity reduced between 30.3% and 59.4% when CWP increased from 0% to 30% as compared to RCB with stirrups spacing of 270 mm without CWP. However, compared to RCB with stirrups spacings of 200 mm and 160 mm without CWP, there were decreases in the load-carrying capacity as 21.4%–54.3% and 18.6%–54.6%, respectively. While the CWP ratio increased, the specimens with 160 mm, 200 mm, and 270 mm stirrups spacings obtained a lower maximum load value. However, with the increase of the CWP ratio in the specimens with 160 mm stirrups spacing, RCBs reached the maximum load-carrying capacity at an earlier displacement value. When stirrups spacing was selected as 270 mm, it was observed that the maximum load-carrying capacity of RCBs reached at a similar displacement value as the CWP ratio increased. Besides, it was resulted that the bending stiffness of RCBs reduced as the quantity of CWP enhanced. The bending stiffness decreased by 29.1% to 66.4% in the specimens with 270 mm stirrups spacing, 36.3% to 20.2% with 200 mm stirrups spacing, and 10.3% to 36.9% with 160 mm stirrups spacing. As an implication of the experiments, the use of CWP up to 10% in RCBs was realized as an economical and environmental approach and is suggested. There is some evidence to report that making use of CWP may be considered to be ecologically benign. This is due to the fact that reusing CWP may significantly reduce CO2 emissions, save energy, and reduce total power consumption. Furthermore, the experimental results were compared to the analytical calculations.
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