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- Baad-Hansen, Lene, et al.
(författare)
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Chair-side intraoral somatosensory examination in patients with atypical odontalgia and healthy subjects
- 2012
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Chair-side intraoral somatosensory examination in patients with atypical odontalgia and healthy subjects L Baad-Hansen, M Pigg, S Elmasry Ivanovic, H Faris, T List, M Drangsholt, P Svensson Aim of investigation: In patients with persistent orofacial pain, assessment of somatosensory function is recommended. A chair-side qualitative examination with good reliability revealing signs of hyper-/hyposensitivity to touch, cold and painful pinprick stimulation may be performed. The aim of this multicenter study was to compare three qualitative measures of intraoral somatosensory function between patients with atypical odontalgia (AO) and healthy subjects. Methods: 31 AO patients (6 male, 25 female; mean age: 54±13) and 47 healthy age- and sex-matched controls (15 male, 32 female: mean age: 47±12) were recruited from Malmö University (Sweden), University of Washington (USA) and Aarhus University (Denmark). In AO patients, sensitivity to touch, cold, and pinprick stimuli was evaluated on the buccal gingiva adjacent to the painful site and the corresponding contralateral ‘mirror-image’ gingival site. In healthy subjects, tests were performed bilaterally on the buccal gingiva adjacent to the first maxillary premolars. Patients were asked to report hyper-, hypo-, or normo-sensitivity/- algesia to touch, cold and painful stimuli on the painful site compared with the contralateral site; healthy subjects were asked to compare sensitivity between sides. Χ2-tests were used to analyze differences in frequency of hyper-, hyposensitivity or normosensitivity between groups. Results: The frequency of subjectively reported normosensitivity to all stimulus modalities were significantly lower in patients (23-58%) than in healthy subjects (68-91%), P<0.001. Frequency of hypersensitivity to all modalities were significantly higher in patients (29-61%) than in controls (9-17%), P<0.015, whereas reports of hyposensitivity were similar between groups (2-16%), P>0.054. Conclusion: A quick and simple chair-side evaluation of intraoral somatosensory function can detect intraoral sensory disturbances in AO patients, mainly in the form of hyper-sensitivity. These tests may be useful in the initial screening of patients with persistent orofacial pain.
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| 2. |
- Baad-Hansen, Lene, et al.
(författare)
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Chairside intraoral qualitative somatosensory testing : reliability and comparison between patients with atypical odontalgia and healthy controls
- 2013
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Ingår i: Journal of Orofacial Pain. - : Quintessence. - 1064-6655 .- 1945-3396. ; 27:2, s. 165-170
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: To assess intraoral inter- and intraexaminer reliability of three qualitative measures of intraoral somatosensory function and to compare these measures between patients with atypical odontalgia (AO) and healthy controls. METHODS: Thirty-one AO patients and 47 healthy controls participated. Inter- and intraexaminer reliability was tested on a subgroup of 46 subjects (25 AO; 21 healthy). Sensitivity to touch, cold, and pinprick stimuli was evaluated on the painful gingival site and the corresponding contralateral site in AO patients, and bilaterally on the gingiva of the first maxillary premolars in controls. Patients were asked to report hypersensitivity, hyposensitivity, or normal sensitivity to stimuli on the painful site compared with the nonpainful site. Kappa values were calculated, and chi-square and Fisher's exact tests were used to compare frequencies between groups. RESULTS: Kappa values ranged between 0.63 and 0.75. The frequency of hypersensitivity to either modality was significantly higher in patients (29% to 61%) than in controls (9% to 17%) (P < .015), whereas reports of hyposensitivity were similar between groups (2% to 16%) (P > .057). Only 3.2% of the AO patients had no reports of abnormal sensitivity on any of the tests, compared with 59.6% of the healthy subjects (P < .001). CONCLUSION: Intraoral qualitative somatosensory testing can detect intraoral sensory disturbances in AO patients, and the reliability is sufficient for initial screening of orofacial somatosensory function.
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| 3. |
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| 4. |
- Baad-Hansen, Lene, et al.
(författare)
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Intraoral somatosensory abnormalities in patients with atypical odontalgia : a controlled multicenter quantitative sensory testing study
- 2013
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Ingår i: Pain. - : Elsevier. - 0304-3959 .- 1872-6623. ; 154:8, s. 1287-1294
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Tidskriftsartikel (refereegranskat)abstract
- Intraoral somatosensory sensitivity in patients with atypical odontalgia (AO) has not been investigated systematically according to the most recent guidelines. The aims of this study were to examine intraoral somatosensory disturbances in AO patients using healthy subjects as reference, and to evaluate the percent agreement between intraoral quantitative sensory testing (QST) and qualitative sensory testing (QualST). Forty-seven AO patients and 69 healthy control subjects were included at Universities of Washington, Malmö, and Aarhus. In AO patients, intraoral somatosensory testing was performed on the painful site, the corresponding contralateral site, and at thenar. In healthy subjects, intraoral somatosensory testing was performed bilaterally on the upper premolar gingiva and at thenar. Thirteen QST and 3 QualST parameters were evaluated at each site, z-scores were computed for AO patients based on the healthy reference material, and LossGain scores were created. Compared with control subjects, 87.3% of AO patients had QST abnormalities. The most frequent somatosensory abnormalities in AO patients were somatosensory gain with regard to painful mechanical and cold stimuli and somatosensory loss with regard to cold detection and mechanical detection. The most frequent LossGain code was L0G2 (no somatosensory loss with gain of mechanical somatosensory function) (31.9% of AO patients). Percent agreement between corresponding QST and QualST measures of thermal and mechanical sensitivity ranged between 55.6% and 70.4% in AO patients and between 71.1% and 92.1% in control subjects. In conclusion, intraoral somatosensory abnormalities were commonly detected in AO patients, and agreement between quantitative and qualitative sensory testing was good to excellent.
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| 5. |
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| 6. |
- El-Masry Ivanovic, Susanne, et al.
(författare)
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PRELIMINARY REPORT OF RELIABILITY OF QUANTITATIVE SENSORY TESTING (QST) IN PATIENTS WITH PERSISTENT IDIOPATHIC DENTOALVEOLAR PAIN
- 2010
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Ingår i: Abstracts of the 13th World Congress of Pain. - : IASP (International Association for the Study of Pain and Omnipress).
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The German Network for Neuropathic Pain (DFNS) has recommended a protocol with 13 quantitative sensory testing (QST) measures for detection of somatosensory abnormalities. We have recently reported that the reliability of intraoral QST in healthy subjects is acceptable for most QST measures. This study investigated the inter- and intra-examiner reliability of 13 intraoral QST measures at the painful site and pain-free control site in patients with persistent idiopathic dentoalveolar pain. Methods: Seven female patients (61 ± 14 years) with atypical odontalgia (AO), a chronic continuous dentoalveolar pain (CCDAP) condition, have so far been included in this ongoing study. The average AO pain was 6.3 ± 2.4 assessed on a 0-10 numerical rating scale (NRS). Two trained, blinded examiners examined the patients using the DNFS QST protocol. Each patient was examined twice on the same day, once by each examiner (inter-examiner reliability). After 1-2 weeks, one examiner examined all patients again (intra-examiner reliability). The parameters tested were: thresholds for detection of cold (CDT) and warmth (WDT), pain on cold (CPT) and heat (HPT), thermal sensory limen (TSL) and paradoxical heat sensations during this procedure (PHS); thresholds for mechanical detection (MDT) and pain (MPT), vibration detection (VDT) and pressure pain (PPT); mechanical pain sensitivity (MPS), dynamic mechanical allodynia (DMA) and wind-up ratio (WUR) for pinprick pain were also recorded. All testing was made at the buccal gingiva adjacent to the painful tooth (P) and at a corresponding contralateral gingival site (CO). The skin of the right hand (thenar) was also tested. Intraclass correlation coefficient (ICC) for continuous variables and kappa value for categorical variables (PHS, DMA) were used to calculate correlations ICC <0.4 was considered poor; 0.4-0.59 fair; 0.6-0.75 good; and >0.75 excellent agreement, and for Kappa: ≤ 0.2 poor; 0.21-0.40 fair; 0.41-0.60 moderate; 0.61-0.80 good; and 0.81-1.00 excellent agreement. Results: On CO site, intra-examiner reliability was excellent for MPS, DMA and VDT; fair-good for CDT, TSL, MPT and WUR; poor for HPT, MDT and PPT. Inter-examiner reliability: excellent for DMA and VDT; fair-good for CDT, TSL, MPT and MPS; poor for WDT, CPT, HPT, MDT, WUR and PPT. On P site, intra-examiner reliability was excellent for MPS, VDT and PPT; fair-good for WDT, TSL, MDT and WUR; poor for CDT, CPT, HPT, DMA and MPT. Inter-examiner reliability: fair-good for CDT, CPT, MDT, MPT, MPS, VDT and PPT; poor for WDT, TSL, PHS, HPT, DMA and WUR. Conclusions: This initial assessment of the inter- and intra-examiner reliability of intraoral QST measures shows, that most are acceptable for assessment of somatosensory function in patients with persistent idiopathic dentoalveolar pain.
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| 7. |
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| 8. |
- Sallam, Malik, et al.
(författare)
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Low covid-19 vaccine acceptance is correlated with conspiracy beliefs among university students in Jordan
- 2021
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Ingår i: International Journal of Environmental Research and Public Health. - : MDPI AG. - 1661-7827 .- 1660-4601. ; 18:5
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Tidskriftsartikel (refereegranskat)abstract
- Vaccination to prevent coronavirus disease 2019 (COVID-19) emerged as a promising measure to overcome the negative consequences of the pandemic. Since university students could be considered a knowledgeable group, this study aimed to evaluate COVID-19 vaccine acceptance among this group in Jordan. Additionally, we aimed to examine the association between vaccine conspiracy beliefs and vaccine hesitancy. We used an online survey conducted in January 2021 with a chain-referral sampling approach. Conspiracy beliefs were evaluated using the validated Vaccine Conspiracy Belief Scale (VCBS), with higher scores implying embrace of conspiracies. A total of 1106 respondents completed the survey with female predominance (n = 802, 72.5%). The intention to get COVID-19 vaccines was low: 34.9% (yes) compared to 39.6% (no) and 25.5% (maybe). Higher rates of COVID-19 vaccine acceptance were seen among males (42.1%) and students at Health Schools (43.5%). A Low rate of influenza vaccine acceptance was seen as well (28.8%), in addition to 18.6% of respondents being anti-vaccination altogether. A significantly higher VCBS score was correlated with reluctance to get the vaccine (p <0.001). Dependence on social media platforms was significantly associated with lower intention to get COVID-19 vaccines (19.8%) compared to dependence on medical doctors, scientists, and scientific journals (47.2%, p <0.001). The results of this study showed the high prevalence of COVID-19 vaccine hesitancy and its association with conspiracy beliefs among university students in Jordan. The implementation of targeted actions to increase the awareness of such a group is highly recommended. This includes educational programs to disman-tle vaccine conspiracy beliefs and awareness campaigns to build recognition of the safety and efficacy of COVID-19 vaccines.
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