| 1. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Thomas, HS, et al.
(författare)
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- 2019
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swepub:Mat__t
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| 3. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 4. |
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| 5. |
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| 6. |
- Ruilope, LM, et al.
(författare)
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Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial
- 2019
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Ingår i: American journal of nephrology. - : S. Karger AG. - 1421-9670 .- 0250-8095. ; 50:5, s. 345-356
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Tidskriftsartikel (refereegranskat)abstract
- <b><i>Background:</i></b> Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. <b><i>Patients and</i></b> <b><i>Methods:</i></b> The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate ≥25 mL/min/1.73 m<sup>2</sup> and albuminuria (urinary albumin-to-creatinine ratio ≥30 to ≤5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. <b><i>Conclusions:</i></b> FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049.
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| 7. |
- Cheema, H. A., et al.
(författare)
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In-hospital mortality of COVID-19 patients hospitalized with ST-segment elevation myocardial infarction : A meta-analysis
- 2022
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Ingår i: IJC Heart & Vasculature. - : Elsevier BV. - 2352-9067. ; 43
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Coronavirus Disease 2019 (COVID-19) has been associated with an increased risk of adverse cardiovascular events including arteriovenous thrombosis, myocarditis and acute myocardial injury. Relevant literature to date has reported widely varying estimates of mortality, ranging from approximately 2 to 11 times higher odds of mortality in COVID-19-positive STEMI (ST-segment elevation myocardial infarction) patients. Hence, we conducted this meta-analysis to resolve these inconsistencies and assess the impact of COVID-19 infection on mortality and other clinical outcomes in patients presenting with STEMI. Methods: This meta-analysis was registered in PROSPERO (CRD42021297458) and performed according to the Cochrane Handbook for Systematic Reviews of Interventions. PubMed and Embase were searched from inception to November 2021 (updated on April 2022) using a search strategy consisting of terms relating to COVID-19, STEMI, and mortality. Results: We identified 435 studies through our initial search. After screening according to our eligibility criteria, a total of 11 studies were included. Compared with the non-COVID-19 STEMI patients, the in-hospital mortality rate was higher in COVID-19-positive STEMI patients. Similarly, the risk of cardiogenic shock was higher in the COVID-19-positive patients. Length of hospital stay was longer in STEMI patients with COVID-19. Conclusions: Our study highlights the necessity for early evaluation of COVID-19 status in all STEMI patients followed by risk stratification, prompt reperfusion and more aggressive management of COVID-19-positive patients. Further research is needed to elucidate the mechanisms behind poorer prognosis in such patients.
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| 8. |
- Bhatti, M. K., et al.
(författare)
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Scheduling of Parallel Tasks with Proportionate Priorities
- 2016
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Ingår i: Arabian Journal for Science and Engineering. - : Springer Verlag. - 2193-567X .- 1319-8025 .- 2191-4281. ; 41:8, s. 3279-3295
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Tidskriftsartikel (refereegranskat)abstract
- Parallel computing systems promise higher performance for computationally intensive applications. Since programmes for parallel systems consist of tasks that can be executed simultaneously, task scheduling becomes crucial for the performance of these applications. Given dependence constraints between tasks, their arbitrary sizes, and bounded resources available for execution, optimal task scheduling is considered as an NP-hard problem. Therefore, proposed scheduling algorithms are based on heuristics. This paper presents a novel list scheduling heuristic, called the Noodle heuristic. Noodle is a simple yet effective scheduling heuristic that differs from the existing list scheduling techniques in the way it assigns task priorities. The priority mechanism of Noodle maintains a proportionate fairness among all ready tasks belonging to all paths within a task graph. We conduct an extensive experimental evaluation of Noodle heuristic with task graphs taken from Standard Task Graph. Our experimental study includes results for task graphs comprising of 50, 100, and 300 tasks per graph and execution scenarios with 2-, 4-, 8-, and 16-core systems. We report results for average Schedule Length Ratio (SLR) obtained by producing variations in Communication to Computation cost Ratio. We also analyse results for different degree of parallelism and number of edges in the task graphs. Our results demonstrate that Noodle produces schedules that are within a maximum of 12 % (in worst-case) of the optimal schedule for 2-, 4-, and 8-core systems. We also compare Noodle with existing scheduling heuristics and perform comparative analysis of its performance. Noodle outperforms existing heuristics for average SLR values.
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| 9. |
- Colbourne, JK, et al.
(författare)
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The Precision Toxicology initiative
- 2023
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Ingår i: Toxicology letters. - 1879-3169. ; 383, s. 33-42
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Dini, P., et al.
(författare)
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Proceedings - 5th International Conference on Software Engineering Advances, ICSEA 2010 : Preface
- 2010
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Ingår i: International Conference on Software Engineering Advances (ICSEA). - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. xii-xiii
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Konferensbidrag (populärvet., debatt m.m.)abstract
- Presents the introductory welcome message from the conference proceedings. May include the conference officers' congratulations to all involved with the conference event and publication of the proceedings record.
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| 11. |
- Farooq, M. U., et al.
(författare)
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Generalized LDPC Codes with Convolutional Code Constraints
- 2020
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Ingår i: 2020 IEEE International Symposium on Information Theory (ISIT). - 9781728164328 - 9781728164335 ; , s. 479-484
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Konferensbidrag (refereegranskat)abstract
- Braided convolutional codes (BCCs) are a class of spatially coupled turbo-like codes that can be described by a (2), (3)-regular compact graph. In this paper, we introduce a family of (d v , d c )-regular GLDPC codes with convolutional code constraints (CC-GLDPC codes), which form an extension of classical BCCs to arbitrary regular graphs. In order to characterize the performance in the waterfall and error floor regions, we perform an analysis of the density evolution thresholds as well as the finite-length ensemble weight enumerators and minimum distances of the ensembles. In particular, we consider various ensembles of overall rate R = 1/3 and R = 1/2 and study the trade-off between variable node degree and strength of the component codes. We also compare the results to corresponding classical LDPC codes with equal degrees and rates. It is observed that for the considered LDPC codes with variable node degree d v > 2, we can find a CC-GLDPC code with smaller d v that offers similar or better performance in terms of BP and MAP thresholds at the expense of a negligible loss in the minimum distance.
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| 12. |
- Farooq, U., et al.
(författare)
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A step forward towards synthesizing a stable and regeneratable nanocomposite for remediation of trichloroethene
- 2018
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Ingår i: Chemical Engineering Journal. - : Elsevier BV. - 1385-8947 .- 1873-3212. ; 347, s. 660-668
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Tidskriftsartikel (refereegranskat)abstract
- Synthesizing supported heterogeneous catalysts is always considered as a persistent approach for degradation of contaminants. However, the stability of these nanocomposites and improvement of process conditions influencing target pollutants degradation are still limited. Herein, on the basis of self-adhesive nature of polydopamine (PDA) and its strong electrostatic interaction with metallic ions, we synthesized a facile, stable, magnetically separable, and environmentally benign PDA decorated, reduced graphene oxide (rGO) supported Fe nanocatalyst (PDA@Fe/rGO). The effects of process variables (pH, PDA@Fe/rGO, and persulphate (PS) dose) on the degradation performance of trichloroethene (TCE), a model chlorinated organic pollutant selected in this study, were investigated. PDA not only encapsulated the host Fe/rGO magnetic particles but also exhibited high magnetization. PDA wrapping tremendously enhanced the thermal stability of nanocatalyst with just 24.1% weight loss at elevated temperature compared to solo Fe/rGO (40.2%). Moreover, TCE degradation mechanism was interpreted by ESR and radical scavenger tests, validating OH[rad], SO4 [rad]− and O2 [rad]− radicals being responsible for TCE degradation. Considering its eminent catalytic activity, simple synthesis approach and excellent kinetics, this recyclable and improved PDA assisted Fe/rGO nanocatalyst further opens a door for practical implementation in the field of contaminated groundwater remediation.
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| 13. |
- Farooq, U., et al.
(författare)
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Efficient transformation in characteristics of cations supported-reduced graphene oxide nanocomposites for the destruction of trichloroethane
- 2017
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Ingår i: Applied Catalysis A. - : Elsevier B.V.. - 0926-860X .- 1873-3875. ; 544, s. 10-20
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Tidskriftsartikel (refereegranskat)abstract
- Experiments were conducted to investigate the use of graphene-oxide supported metallic nanocomposites for improving the degradation of trichloroethane (TCA) by sodium percarbonate (SPC). Two methods of production, chemical reduction (CR) and solvo-thermal (ST), were tested for preparation of single (Fe) and binary (Fe-Cu) nanocomposites supported by reduced graphene oxide (rGO). A variety of analytical techniques including N2 adsorption Brunauer-Emmett-Teller (BET), x-ray diffraction (XRD), fourier-transfrom infrared spectroscopy (FTIR), and transmisison electron microscopy (TEM) were applied to characterize the physicochemical and microstructural properties of the synthesized nanocomposites. The characterization indicated that the CR method produced nanocomposites that comprised only mesoporous structure. Conversely, both micro and mesoporous structures were present for samples produced with the ST method. The synthesized single and bimetallic composites produced from the ST method showed higher surface areas, i.e. 93.6 m2/g and 119.2 m2/g as compared to the ones synthesized via the CR method, i.e. 13.8 m2/g and 38.0 m2/g respectively. The results of FTIR and XRD analyses confirmed that the ST method produced highly crystalline nanocomposites. SEM and TEM analysis validated that metallic particles with definite morphology well distributed on the surface of rGO. X-ray photoelectron spectroscopy (XPS) analysis confirmed the homogeneity nanocomposites and occurrence of variation in copper oxidation states during degradation process. EDS mapping validate the homogeneous distribution of Cu and Fe at reduced graphene oxide surface. The Fe-Cu/rGO (ST) activated SPC system effectively degraded TCA (92%) in 2.5 h at low nanocomposite dose compared to the Fe-Cu/rGO (CR) and only Fe, for which the maximum degradation efficiencies achieved were 81% and 34%. In conclusion, excellent catalytic characteristics were observed for the ST-synthesized single and bimetallic (Fe/rGO, Fe-Cu/rGO) catalysts. These catalysts were successful in improving the degradation of TCA via activated SPC.
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| 14. |
- Ihlow, F., et al.
(författare)
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Geographic range extension of Speke's hinge-back tortoise kinixys spekii gray, 1863
- 2019
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Ingår i: Amphibian and Reptile Conservation. - 1083-446X. ; 13:2, s. 61-67
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Tidskriftsartikel (refereegranskat)abstract
- Kinixys spekii has a wide distribution range across sub-Saharan Africa, having been reported from Angola, Botswana, Burundi, the Democratic Republic of the Congo, eSwatini, Kenya, Malawi, Mozambique, Namibia, South Africa, Tanzania, Zambia, and Zimbabwe. Kinixys spekii inhabits savannah and dry bushveld habitats and was previously considered an inland species. However, recent records suggest a more extensive geographical distribution. Here, we provide genetically verified records for Angola, South Africa, and Mozambique, and discuss reliable sightings for Rwanda. These new records extend the range significantly to the east and west, and provide evidence for the occurrence of this species along the coast of the Indian Ocean in South Africa and Mozambique. © 2019 Ihlow et al.
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| 15. |
- Khan, H. R., et al.
(författare)
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Cross-cultural prevalence of sleep quality and psychological distress in healthcare workers during COVID-19 pandemic
- 2021
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Ingår i: Brain and Behavior. - : John Wiley & Sons. - 2162-3279 .- 2162-3279. ; 11:11
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Tidskriftsartikel (refereegranskat)abstract
- Background: Poor quality sleep and emotional disturbances are expected in times of crisis. COVID-19 has severely impacted healthcare worldwide and with that comes the concern about its effects on healthcare workers. The purpose of the present study was to assess sleep quality and psychological distress in healthcare workers during the COVID-19 pandemic.Methods: The present work is a multi-centric cross-sectional study targeting healthcare workers from India, Pakistan, and Nepal. It used an online version of the Pittsburg Sleep Quality Index and the General Health Questionnaire, and data were analyzed using SPSS V.24.Results: A total of 1790 participants completed the questionnaire. Of the 1790 participants, 57% reported poor sleep quality, and 10% reported a high level of psychological distress. A cross-cultural comparison found some differences between the different groups of participants. The details of the differences were further explored in the article.Conclusion: The present study highlights that a significant proportion of healthcare workers are affected by poor sleep quality and psychological distress during the COVID-19 pandemic. It also emphasizes the imperative to provide them with psychosocial support to avoid potential short- and long-term psychological consequences of these troubling times.
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| 16. |
- Naqvi, Muhammad, et al.
(författare)
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Polygeneration system integrated with small non-wood pulp mills for substitute natural gas production
- 2018
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Ingår i: Applied Energy. - : Elsevier. - 0306-2619 .- 1872-9118. ; 224, s. 636-646
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Tidskriftsartikel (refereegranskat)abstract
- This study aims to examine the potential substitute natural gas (SNG) production by integrating black liquor gasification (BLG) island with a small wheat straw-based non-wood pulp mills (NPM), which do not employ the black liquor recovery cycle. For such integration, it is important to first build knowledge on expected improvements in an overall integrated non-wood pulp mill energy system using the key performance indicators. O2-blown circulating fluidized bed (CFB) gasification with direct causticization is integrated with a reference small NPM to evaluate the overall performance. A detailed economic analysis is performed together with a sensitivity analysis based on variations in the rate of return due to varying biomass price, total capital investment, and natural gas prices. The quantitive results showed considerable SNG production but significantly reduced electricity production. There is a substantial CO2 abatement potential combining CO2 capture and CO2 mitigation from SNG use replacing compressed natural gas (CNG) or gasoline. The economic performance through sensitivity analysis reflects significant dependency on both substitute natural gas production and natural gas market price. Furthermore, the solutions to address the challenges and barriers for the successful commercial implementation of BLG based polygeneration system at small NPMs are discussed. The system performance and discussion on the real application of integrated system presented in this article form a vital literature source for future use by large number of small non-wood pulp industries.
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| 17. |
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| 18. |
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