| 1. |
- Arridge, Christopher S., et al.
(författare)
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Uranus Pathfinder : exploring the origins and evolution of Ice Giant planets
- 2012
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Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 33:2-3, s. 753-791
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Tidskriftsartikel (refereegranskat)abstract
- The "Ice Giants" Uranus and Neptune are a different class of planet compared to Jupiter and Saturn. Studying these objects is important for furthering our understanding of the formation and evolution of the planets, and unravelling the fundamental physical and chemical processes in the Solar System. The importance of filling these gaps in our knowledge of the Solar System is particularly acute when trying to apply our understanding to the numerous planetary systems that have been discovered around other stars. The Uranus Pathfinder (UP) mission thus represents the quintessential aspects of the objectives of the European planetary community as expressed in ESA's Cosmic Vision 2015-2025. UP was proposed to the European Space Agency's M3 call for medium-class missions in 2010 and proposed to be the first orbiter of an Ice Giant planet. As the most accessible Ice Giant within the M-class mission envelope Uranus was identified as the mission target. Although not selected for this call the UP mission concept provides a baseline framework for the exploration of Uranus with existing low-cost platforms and underlines the need to develop power sources suitable for the outer Solar System. The UP science case is based around exploring the origins, evolution, and processes at work in Ice Giant planetary systems. Three broad themes were identified: (1) Uranus as an Ice Giant, (2) An Ice Giant planetary system, and (3) An asymmetric magnetosphere. Due to the long interplanetary transfer from Earth to Uranus a significant cruise-phase science theme was also developed. The UP mission concept calls for the use of a Mars Express/Rosetta-type platform to launch on a Soyuz-Fregat in 2021 and entering into an eccentric polar orbit around Uranus in the 2036-2037 timeframe. The science payload has a strong heritage in Europe and beyond and requires no significant technology developments.
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| 2. |
- Williamson, Alice, et al.
(författare)
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Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake
- 2023
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Ingår i: Nature Genetics. - : Springer Nature. - 1061-4036 .- 1546-1718. ; 55:6, s. 973-983
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Tidskriftsartikel (refereegranskat)abstract
- Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on insulin resistance in the fasting state, where hepatic insulin action dominates. Here we studied genetic variants influencing insulin levels measured 2 h after a glucose challenge in >55,000 participants from three ancestry groups. We identified ten new loci (P < 5 × 10-8) not previously associated with postchallenge insulin resistance, eight of which were shown to share their genetic architecture with type 2 diabetes in colocalization analyses. We investigated candidate genes at a subset of associated loci in cultured cells and identified nine candidate genes newly implicated in the expression or trafficking of GLUT4, the key glucose transporter in postprandial glucose uptake in muscle and fat. By focusing on postprandial insulin resistance, we highlighted the mechanisms of action at type 2 diabetes loci that are not adequately captured by studies of fasting glycemic traits.
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| 3. |
- Wang, Rongsheng, et al.
(författare)
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Asymmetry in the current sheet and secondary magnetic flux ropes during guide field magnetic reconnection
- 2012
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Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 117, s. A07223-
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Tidskriftsartikel (refereegranskat)abstract
- A magnetic reconnection event with a moderate guide field encountered by Cluster in the near-Earth tail on 28 August 2002 is reported. The guide field points dawnward during this event. The quadrupolar structure of the Hall magnetic field within the ion diffusion region is distorted toward the northern hemisphere in the earthward part while toward the southern hemisphere tailward part of X-line. Observations of current density and electron pitch angle distribution indicate that the distorted quadrupolar structure is formed due to a deformed Hall electron current system. Cluster crossed the ion diffusion region from south to north earthward of the X-line. An electron density cavity is confirmed in the northern separatrix layer while a thin current layer (TCL) is measured in the southern separatrix layer. The TCL is formed due to electrons injected into the X-line along the magnetic field. These observations are different from simulation results where the cavity is produced associated with inflow electrons along the southern separatrix while the strong current sheet appears with the outflow electron beam along the northern separatrix. The energy of the inflowing electron in the separatrix layer could extend up to 10 keV. Energetic electron fluxes up to 50 keV have a clear peak in the TCL. The length of the separatrix layer is estimated to be at least 65 c/omega(pi). These observations suggest that electrons could be pre-accelerated before they are ejected into the X-line region along the separatrix. Multiple secondary flux ropes moving earthward are observed within the diffusion region. These secondary flux ropes are all identified earthward of the observed TCL. These observations further suggest there are numerous small scale structures within the ion diffusion region.
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| 4. |
- Wang, Rongsheng, et al.
(författare)
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Observation of double layer in the separatrix region during magnetic reconnection
- 2014
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Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 41:14, s. 4851-4858
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Tidskriftsartikel (refereegranskat)abstract
- We present in situ observation of double layer (DL) and associated electron measurement in the subspin time resolution in the separatrix region during reconnection for the first time. The DL is inferred to propagate away from the X line at a velocity of about ion acoustic speed and the parallel electric field carried by the DL can reach -20 mV/m. The electron displays a beam distribution inside the DL and streams toward the X line with a local electron Alfven velocity. A series of electron holes moving toward the X line are observed in the wake of the DL. The identification of multiple similar DLs indicates that they are persistently produced and therefore might play an important role in energy conversion during reconnection. The observation suggests that energy dissipation during reconnection can occur in any region where the DL can reach.
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| 5. |
- Wang, Rongsheng, et al.
(författare)
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Observation of multiple sub-cavities adjacent to single separatrix
- 2013
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Ingår i: Geophysical Research Letters. - : American Geophysical Union (AGU). - 0094-8276 .- 1944-8007. ; 40:11, s. 2511-2517
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Tidskriftsartikel (refereegranskat)abstract
- We investigate a direct south-north crossing of a reconnection ion diffusion region in the magnetotail. During this crossing, multiple electron density dips with a further density decrease within the cavity, called sub-cavities, adjacent to the northern separatrix are observed. The correlation between electron density sub-cavities and strong electric field fluctuations is obvious. Within one of the sub-cavities, a series of very strong oscillating perpendicular electric field and patchy parallel electric field are observed. The parallel electric field is nearly unipolar and directs away from X line. In the same region, inflow electrons with energy up to 100keV are injected into the X line. Based on the observations, we conclude that the high-energy inflowing electrons are accelerated by the patchy parallel electric field. Namely, electrons have been effectively accelerated while they are flowing into the X line along the separatrix. The observations indicate that the electron acceleration region is widely larger than the predicted electron diffusion region in the classical Hall magnetic reconnection model.
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