| 1. |
- Friman, Johanna, et al.
(författare)
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Feeding silage to fattening pigs – effects on nitrogen utilization and ammonia losses from fresh manure
- 2023
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Ingår i: Acta agriculturae Scandinavica. Section A, Animal science. - : Taylor & Francis. - 0906-4702 .- 1651-1972. ; 72:3, s. 111-
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Tidskriftsartikel (refereegranskat)abstract
- ABSTRACTThis study evaluated the effect of feeding silage to pigs on nitrogen (N) utilization and ammonia (NH3) volatilization. In total, 128 Yorkshire ? Hampshire (30?110?kg) pigs were fed commercial feed (Control) or commercial feed mixed with dried, milled silage in pelleted form (Pellet-S), fresh, chopped silage (Silage-Ch) or intensively treated silage (Silage-Pr). Silage replaced 20% of the crude protein (g/kg). Diet affected daily N excretion, which was higher for pigs fed Silage-Ch and Silage-Pr than for pigs in the Pellet-S and Control treatments. Ammonium nitrogen (NH4-N) content in the manure and NH3 volatilization from fresh manure were higher for Control pigs than for pigs in the other treatments. Overall, these results show that pre-treatment of silage influences N utilization and excretion. Furthermore, the results indicate that feeding silage to pigs can reduce NH3 volatilization from fresh manure.
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| 2. |
- Friman, Johanna, et al.
(författare)
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Grass/clover silage for growing/finishing pigs – effect of silage pre-treatment and feeding strategy on growth performance and carcass traits
- 2021
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Ingår i: Acta Agriculturae Scandinavica, Section A - Animal Science. - : Informa UK Limited. - 0906-4702 .- 1651-1972. ; 70, s. 151-160
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Tidskriftsartikel (refereegranskat)abstract
- This study evaluated the influence of feeding strategy and grass/clover silage pre-treatment on pig growth performance and carcass traits. In total, 128 pigs weighing 30–110 kg were fed either a commercial control feed or received silage in a pellet (SP) or in a total mixed ratio (TMR) containing chopped silage (SC) or intensively treated silage (SE). Silage replaced 20% of dietary crude protein content (g/kg). Diet affected weight gain (P = 0.001), with pigs fed the SP diet showing best overall growth performance. Pigs fed the SC diet had the lowest weight gain (P = 0.001), while pigs fed the SE diet performed similarly to those fed the control diet. Carcass weight and dressing percentage differed between the diets (P = 0.016 and P = 0.018), but there was no difference in lean meat content (P = 0.832). The results show satisfactory growth performance and carcass traits, indicating that silage can replace other protein sources in growing/finishing pig diets.
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| 3. |
- Friman, Johanna, et al.
(författare)
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Inclusion of silage in diets to fattening pigs: effect on gastric ulcers and skin lesions
- 2024
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Ingår i: Animal. - 1751-7311 .- 1751-732X. ; 1
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Tidskriftsartikel (refereegranskat)abstract
- Limited access to high-quality feed protein for pigs has made it necessary to evaluate new protein sources that both promote sustainable pig production and meet the nutritional requirements of pigs. Providing pigs with roughage has positive effects on their behaviour and gut health. However, roughage is seldom given as a part of the pigs’ diet and often has a long straw length. Knowledge is lacking on the effect of feeding silage with smaller particle size and as a part of the pigs' diet on pig behaviour and welfare. This study evaluated the influence of feeding fattening pigs silage with different particle sizes on aggressive encounters, measured as the number of skin lesions, and on the occurrence of gastric lesions and ulcers. In total, 128 Swedish Yorkshire × Hampshire pigs were fed either a commercial control feed without silage (Pellet-C), or silage mixed with commercial feed, either in a pellet (Pellet-S) or in a total mixed ration (TMR) with chopped (TMR-Ch) or intensively treated silage (TMR-Ex). Skin lesions were assessed twice in the study according to the Welfare Quality® protocol. The first assessment was performed when the pigs were 105 days old and the second assessment at 132 days of age. Gastric lesions were examined in both the pars oesophagea and the pars glandularis region of the stomach. Stomachs were collected after slaughter, and gastric lesions were scored based on established scoring criteria. There was a treatment × assessment interaction on the number of skin lesions on the ear (P = 0.049). Apart from this interaction, no other effect of treatment on the number of skin lesions could be observed between the treatments or the assessment occasions. Treatment had a clear effect on the occurrence of gastric lesions and pigs fed the fresh silage (TMR-Ch and TMR-Ex) had a lower occurrence of gastric lesions and ulcers compared to the pelleted treatments (Pellet-C and Pellet-S) (P = 0.001). This study could not show any clear reduction effect of dietary silage inclusion on skin lesions. However, feeding silage in TMR significantly reduced the occurrence of stomach ulcers.
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| 4. |
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| 5. |
- Friman, Johanna
(författare)
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Ley crop silage in diets to fattening pigs : How does it affect pig performance, nitrogen utilization, health and behaviour?
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- There is an increasing interest to use silage as a feed ingredient to pigs. The aim of this thesis was to study the effect of using silage in the diet to fattening pigs and how feeding strategy influenced pig performance, behaviour, gut health and nitrogen utilization. Two studies were performed. Study I focused on 1) pig performance, 2) behaviour and gut health and 3) nitrogen utilization and study II focused on pig behaviour and time budgets. In study I, 128 fattening pigs (30-110 kg) were fed either a commercial control feed (control) or received silage in a pellet (Pellet-S) or in a total mixed ration (TMR) containing fresh, chopped silage (TMR-Ch) or fresh, intensively treated silage (TMR-Ex). In study II, 126 growing pigs (30-70 kg) received a commercial control feed (control) or silage in a pellet (Pell-S) or fresh in a TMR with chopped silage (TMR-S). In both studies, silage replaced 20% of the dietary crude protein content (g/kg). The results in study I showed that pigs fed silage in general had a satisfying growth, but feeding fresh silage slightly reduced the daily weight gain. Pigs fed the pelleted silage had the highest daily weight gain and that feeding fresh silage slightly reduced the daily weight gain, however, pigs fed intensively treated silage performed similar to pigs fed the control diet. In study II, pigs fed TMR with fresh silage spent more and longer time performing foraging behaviours and were overall more active compared to pigs fed the pelleted silage and control diets. Feeding fresh silage reduced occurrences of gastric lesions in the gastric mucosa. Silage-based diets reduced the ammonia volatilization from the manure, which highlights the potential of using silage to reduce the environmental load from pig housing. The results support that silage is a suitable feed ingredient for fattening pigs, with potential to improve pig health and welfare.
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| 6. |
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| 7. |
- Friman, Vanda, 1952, et al.
(författare)
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Defective peripheral B cell selection in common variable immune deficiency patients with autoimmune manifestations
- 2023
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Ingår i: Cell Reports. - : Elsevier. - 2211-1247. ; 42:5
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Tidskriftsartikel (refereegranskat)abstract
- Common variable immune deficiency (CVID) is a heterogeneous disorder characterized by recurrent infections, low levels of serum immunoglobulins, and impaired vaccine responses. Autoimmune manifestations are common, but B cell central and peripheral selection mechanisms in CVID are incompletely understood. Here, we find that receptor editing, a measure of central tolerance, is increased in transitional B cells from CVID patients and that these cells have a higher immunoglobulin κ:λ ratio in CVID patients with autoimmune manifestations than in those with infection only. Contrariwise, the selection pressure in the germinal center on CD27bright memory B cells is decreased in CVID patients with autoimmune manifestations. Finally, functionally, T cell-dependent activation showed that naive B cells in CVID patients are badly equipped for activation and induction of mismatch repair genes. We conclude that central tolerance is functional whereas peripheral selection is defective in CVID patients with autoimmune manifestations, which could underpin the development of autoimmunity.
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| 8. |
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| 9. |
- Thegerström, Johanna, et al.
(författare)
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Clinical features and incidence of Mycobacterium avium infections in children
- 2008
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 40:6-7, s. 481-6
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Tidskriftsartikel (refereegranskat)abstract
- Mycobacterium avium is the most common pathogen in children presenting as non-tuberculous mycobacterial lymphadenitis. In Sweden non-tuberculous mycobacterial infection is a notifiable disease. The goal of our study was to determine the annual incidence of M. avium infection in Swedish children, 1998-2003, and describe clinical features related to age and treatment of children with M. avium lymphadenitis. To do this, we retrospectively analysed patient records of 162 children less than 7 y of age from the entire country with culture-verified M. avium disease. The incidence of M. avium infection in Sweden was lower in 2000-2003 than in 1998-1999. Young children (
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| 10. |
- Thegerström, Johanna, 1972-, et al.
(författare)
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Mycobacterium avium avium and Mycobacterium avium hominissuis give different cytokine responses after in vitro stimulation of human blood mononuclear cells
- 2012
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Ingår i: PLOS ONE. - : PloS. - 1932-6203. ; 7:4, s. e34391-
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Tidskriftsartikel (refereegranskat)abstract
- Background: Mycobacterium avium is the principal etiologic agent of non-tuberculous lymphadenitis in children. It is also a known pathogen for birds and other animals. Molecular epidemiologic evidence indicates that humans and animals are infected with different M. avium subspecies, namely, M. avium subsp. avium and M. avium subsp. hominissuis, respectively.Aim: To investigate the effect on the human immune system of 10 isolates of M. avium subsp. avium mainly isolated from animals and of 11 isolates of M. avium subsp. hominissuis isolated from children with lymphadenitis.Method: Peripheral blood mononuclear cells (PBMC) from six healthy blood donors were stimulated in vitro with the inactivated mycobacteria followed by quantification of IL-10, IL-12p70, TNF, IFN-γ and IL-17 in supernatants by multiplex bead array analysis (Luminex).Results: M. avium subsp. hominissuis induced significantly more IL-10 and significantly less IL-12p70, TNF, IFN-γ and IL-17 compared to M. avium subsp. avium. All strains induced high levels of IL-17, but very little IL-12.Conclusion: The lower T helper (Th) 1 and Th17 responses induced by M. avium subsp. hominissuis compared to M. avium subsp. avium after in vitro stimulation of PBMC might contribute to its higher pathogenicity in humans.
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| 11. |
- Thegerström, Johanna, et al.
(författare)
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Mycobacterium avium lymphadenopathy among children, Sweden
- 2008
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Ingår i: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6040 .- 1080-6059. ; 14:4, s. 661-663
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Tidskriftsartikel (refereegranskat)abstract
- We studied Mycobacterium avium lymphadenopathy in 183 Swedish children (<7 years of age) from 1998 through 2003. Seasonal variation in the frequency of the disease, with a peak in October and a low point in April, suggests cyclic environmental factors. We also found a higher incidence of the disease in children who live close to water.
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| 12. |
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| 13. |
- Vu, Emy, et al.
(författare)
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Vallfoder till gris och dess effekt på produktion, beteende och hälsa samt reproduktion
- 2023
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Ingår i: Report from the Department of Crop Production Ecology (VPE). - 1653-5375. ; , s. 113-116
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Vallfoder kan nyttjas som en lokalt odlad foderresurs till grisar. Utfodring med ett finhackat ensilage som mixas med kraftfoder genererade likvärdiga produktionsegenskaper som utfodring med konventionellt slaktgrisfoder. Därtill sänktes förekomsten av magsår hos grisar som utfodrades med färskt ensilage. Slutligen ökade grisarnas aktivitetsnivå. Idag finns bristande information om hur fytoöstrogener i rödklöverensilage metaboliseras i suggor, med oro för fertilitetsstörningar. Studier på metabolismen av fytoöstrogener och hur de påverkar suggans reproduktionsegenskaper har gjorts, som visar skillnader i fytoöstrogenhalter.
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| 14. |
- Zira, Stanley, et al.
(författare)
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An assessment of scenarios for future pig production using a One Health approach
- 2022
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Ingår i: Livestock Science. - : Elsevier BV. - 1871-1413 .- 1878-0490. ; 260
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Tidskriftsartikel (refereegranskat)abstract
- One Health is an approach to achieve better health and well-being outcomes for people, farmed organisms and their shared environment. The One Health approach was used to analyse the impacts on the environment, people and organisms (including the pigs) of three scenarios for future pig production to ascertain their strengths and weaknesses when compared with a Reference case reflecting today's pig production. The scenarios were: Business as usual scenario (AsUsual), Sustainable Feed scenario (SusFeed), and Sustainable Feed and Pigs bred for feed efficiency and better animal welfare scenario (SusFeedPig). In SusFeed, the pig diets were without soybean meal but with locally produced feed ingredients including yeast protein. The pigs had access to an outdoor veranda, silage and straw for enrichment, and were selected using today's breeding goal. In SusFeedPig, pigs had the same feed as in SusFeed, had access to pasture during summer and were selected using an alternative to today's breeding goal with focus on overall feed efficiency and improved animal welfare. In AsUsual, pigs were fed current diets including soybean meal, had no access to a veranda and silage, and pigs were bred based on today's breeding goals. The different scenarios were assessed using a One Health framework with 13 success metrics. The selection and scoring of indicators for success metrics may be subjective because they depend on individual assessments that can be variable. SusFeed performed better than the Reference case on nine success metrics, SusFeedPig on eight and AsUsual on six. Sustainability in all the future scenarios was improved when compared to the Reference case but SusFeed with the alternative breeding goal was the most preferable scenario due to reduced negative effects for the environment, people and farmed organisms.
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| 15. |
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