| 1. |
- Evangelou, Evangelos, et al.
(författare)
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
- 2018
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 50:10, s. 1412-1425
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Tidskriftsartikel (refereegranskat)abstract
- High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
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| 2. |
- Lou, Xiaolong, et al.
(författare)
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An Integrated Application of Motion Sensing and Eye Movement Tracking Techniques in Perceiving User Behaviors in a Large Display Interaction
- 2023
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Ingår i: Machines. - : MDPI AG. - 2075-1702. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- In public use of a large display, it is a usual phenomenon that multiple users individually participate in respective tasks on a common device. Previous studies have categorized such activity as independent interaction that involves little group engagement. However, by investigating how users approach, participate in, and interact with large displays, we found that parallel use is affected by group factors such as group size and between-user relationship. To gain a thorough understanding of individual and group behaviors, as well as parallel interaction task performance, one 70-inch display-based information searching task and experiment was conducted, in which a mobile eye movement tracking headset and a motion sensing RGB-depth sensor were simultaneously applied. The results showed that (1) a larger group size had a negative influence on the group users’ concentration on the task, perceived usability, and user experience; (2) a close relationship between users contributed to occasional collaborations, which was found to improve the users’ task completion time efficiency and their satisfaction on the large display user experience. This study proves that an integrated application of eye movement tracking and motion sensing is capable of understanding individual and group users’ behaviors simultaneously, and thus is a valid and reliable scheme in monitoring public activities that can be widely used in public large display systems.
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| 3. |
- Lou, Xiaolong, et al.
(författare)
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Distance effects on visual search and visually guided freehand interaction on large displays
- 2022
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Ingår i: International Journal of Industrial Ergonomics. - : Elsevier BV. - 0169-8141 .- 1872-8219. ; 90
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Tidskriftsartikel (refereegranskat)abstract
- Different from mouse-based and touch-based interactions at a static distance, motion-sensing interaction on a large display is typically performed at varying distances ranging from an arm's length to several metres. To investigate the effect of distance on visual search and freehand interaction performance, an empirical experiment was conducted; 30 participants were recruited to complete a series of target search and freehand selection tasks on large displays, which were 1.6 and 2.4 m wide, respectively. The results indicated that (1) the user-preferred viewing distance was positively related to the physical size of the display: a larger display size corresponded to a larger viewing distance. (2) The viewing distance had a two-sided effect on the visual search time efficiency. At a close range, increasing distance improved the search time efficiency; but at a farther range, the efficiency decreased. (3) An optimal field of view at which visual search was most efficient was found; (4) however, increasing the distance lowered freehand interaction efficiency and accuracy. Changing the distance also caused variations in the performance on divided large display areas: (5) the visual search efficiency on the upper area was higher than that on the lower area, increasing the distance reduced the difference; (6) freehand interaction efficiency and accuracy on the lower area outperformed that on the upper area, increasing the distance also reduced the difference. Implications were discussed for building more efficient and user-friendly large display-based user interfaces.
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