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2. |
- de Jong, R. S., et al.
(författare)
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4MOST : Project overview and information for the First Call for Proposals
- 2019
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Ingår i: The Messenger. - : European Southern Observatory. - 0722-6691. ; 175, s. 3-11
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- We introduce the 4-metre Multi-Object Spectroscopic Telescope (4MOST), a new high-multiplex, wide-field spectroscopic survey facility under development for the four-metre-class Visible and Infrared Survey Telescope for Astronomy (VISTA) at Paranal. Its key specifications are: a large field of view (FoV) of 4.2 square degrees and a high multiplex capability, with 1624 fibres feeding two low-resolution spectrographs (R = λ/Δλ ~ 6500), and 812 fibres transferring light to the high-resolution spectrograph (R ~ 20 000). After a description of the instrument and its expected performance, a short overview is given of its operational scheme and planned 4MOST Consortium science; these aspects are covered in more detail in other articles in this edition of The Messenger. Finally, the processes, schedules, and policies concerning the selection of ESO Community Surveys are presented, commencing with a singular opportunity to submit Letters of Intent for Public Surveys during the first five years of 4MOST operations.
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3. |
- Schulze, S., et al.
(författare)
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GRB 120422A/SN 2012bz : Bridging the gap between low- and high-luminosity gamma-ray bursts
- 2014
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 566
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Tidskriftsartikel (refereegranskat)abstract
- Context. At low redshift, a handful of gamma-ray bursts (GRBs) have been discovered with luminosities that are substantially lower (L-iso less than or similar to 10(48.5) erg s(-1)) than the average of more distant ones (L-iso greater than or similar to 10(49.5) erg s(-1)). It has been suggested that the properties of several low-luminosity (low-L) GRBs are due to shock break-out, as opposed to the emission from ultrarelativistic jets. This has led to much debate about how the populations are connected. Aims. The burst at redshift z = 0.283 from 2012 April 22 is one of the very few examples of intermediate-L GRBs with a gamma-ray luminosity of L-iso similar to 10(49.6-49.9) erg s(-1) that have been detected up to now. With the robust detection of its accompanying supernova SN 2012bz, it has the potential to answer important questions on the origin of low-and high-L GRBs and the GRB-SN connection. Methods. We carried out a spectroscopy campaign using medium-and low-resolution spectrographs with 6-10-m class telescopes, which covered a time span of 37.3 days, and a multi-wavelength imaging campaign, which ranged from radio to X-ray energies over a duration of similar to 270 days. Furthermore, we used a tuneable filter that is centred at H alpha to map star-formation in the host and the surrounding galaxies. We used these data to extract and model the properties of different radiation components and fitted the spectral energy distribution to extract the properties of the host galaxy. Results. Modelling the light curve and spectral energy distribution from the radio to the X-rays revealed that the blast wave expanded with an initial Lorentz factor of Gamma(0) similar to 50, which is a low value in comparison to high-L GRBs, and that the afterglow had an exceptionally low peak luminosity density of less than or similar to 2 x 10(30) erg s(-1) Hz(-1) in the sub-mm. Because of the weak afterglow component, we were able to recover the signature of a shock break-out in an event that was not a genuine low-L GRB for the first time. At 1.4 hr after the burst, the stellar envelope had a blackbody temperature of k(B)T similar to 16 eV and a radius of similar to 7 x 10(13) cm (both in the observer frame). The accompanying SN 2012bz reached a peak luminosity of M-V = -19.7 mag, which is 0.3 mag more luminous than SN 1998bw. The synthesised nickel mass of 0.58 M-circle dot, ejecta mass of 5.87 M-circle dot, and kinetic energy of 4.10x10(52) erg were among the highest for GRB-SNe, which makes it the most luminous spectroscopically confirmed SN to date. Nebular emission lines at the GRB location were visible, which extend from the galaxy nucleus to the explosion site. The host and the explosion site had close-to-solar metallicity. The burst occurred in an isolated star-forming region with an SFR that is 1/10 of that in the galaxy's nucleus. Conclusions. While the prompt gamma-ray emission points to a high-L GRB, the weak afterglow and the low Gamma(0) were very atypical for such a burst. Moreover, the detection of the shock break-out signature is a new quality for high-L GRBs. So far, shock break-outs were exclusively detected for low-L GRBs, while GRB 120422A had an intermediate L-iso of similar to 10(49.6-49.9) erg s(-1). Therefore, we conclude that GRB 120422A was a transition object between low-and high-L GRBs, which supports the failed-jet model that connects low-L GRBs that are driven by shock break-outs and high-L GRBs that are powered by ultra-relativistic jets.
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4. |
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5. |
- Bonham, LW, et al.
(författare)
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Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
- 2019
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Ingår i: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1, s. 10854-
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Tidskriftsartikel (refereegranskat)abstract
- The semantic variant of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and progressive loss of semantic knowledge. Unlike many other forms of frontotemporal lobar degeneration (FTLD), svPPA has a highly consistent underlying pathology composed of TDP-43 (a regulator of RNA and DNA transcription metabolism). Previous genetic studies of svPPA are limited by small sample sizes and a paucity of common risk variants. Despite this, svPPA’s relatively homogenous clinicopathologic phenotype makes it an ideal investigative model to examine genetic processes that may drive neurodegenerative disease. In this study, we used GWAS metadata, tissue samples from pathologically confirmed frontotemporal lobar degeneration, and in silico techniques to identify and characterize protein interaction networks associated with svPPA risk. We identified 64 svPPA risk genes that interact at the protein level. The protein pathways represented in this svPPA gene network are critical regulators of RNA metabolism and cell death, such as SMAD proteins and NOTCH1. Many of the genes in this network are involved in TDP-43 metabolism. Contrary to the conventional notion that svPPA is a clinical syndrome with few genetic risk factors, our analyses show that svPPA risk is complex and polygenic in nature. Risk for svPPA is likely driven by multiple common variants in genes interacting with TDP-43, along with cell death,x` working in combination to promote neurodegeneration.
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6. |
- Pastorello, A., et al.
(författare)
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Supernovae 2016bdu and 2005gl, and their link with SN 2009ip-like transients : another piece of the puzzle
- 2018
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 474:1, s. 197-218
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Tidskriftsartikel (refereegranskat)abstract
- Supernova (SN) 2016bdu is an unusual transient resembling SN 2009ip. SN 2009ip-like events are characterized by a long-lasting phase of erratic variability that ends with two luminous outbursts a few weeks apart. The second outburst is significantly more luminous (about 3 mag) than the first. In the case of SN 2016bdu, the first outburst (Event A) reached an absolute magnitude M-r approximate to -15.3 mag, while the second one (Event B) occurred over one month later and reached M-r approximate to -18 mag. By inspecting archival data, a faint source at the position of SN 2016bdu is several times in the past few years. We interpret these detections as signatures of a phase of erratic variability, similar to that experienced by SN 2009ip between 2008 and mid-2012, and resembling the currently observed variability of the luminous blue variable SN 2000ch in NGC 3432. Spectroscopic monitoring of SN 2016bdu during the second peak initially shows features typical of an SN IIn. One month after the Event B maximum, the spectra develop broad Balmer lines with P Cygni profiles and broad metal features. At these late phases, the spectra resemble those of a typical Type II SN. All members of this SN 2009ip-like group are remarkably similar to the Type IIn SN 2005gl. For this object, the claim of a terminal SN explosion is supported by the disappearance of the progenitor star. While the similarity with SN 2005gl supports a genuine SN explosion scenario for SN 2009ip-like events, the unequivocal detection of nucleosynthesized elements in their nebular spectra is still missing.
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7. |
- Pastorello, A., et al.
(författare)
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A luminous stellar outburst during a long-lasting eruptive phase first, and then SN IIn 2018cnf
- 2019
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 628
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Tidskriftsartikel (refereegranskat)abstract
- We present the results of the monitoring campaign of the Type IIn supernova (SN) 2018cnf (a.k.a. ASASSN-18mr). It was discovered about ten days before the maximum light (on MJD = 58 293.4 +/- 5.7 in the V band, with M-V = -18.13 +/- 0.15 mag). The multiband light curves show an immediate post-peak decline with some minor luminosity fluctuations, followed by a flattening starting about 40 days after maximum. The early spectra are relatively blue and show narrow Balmer lines with P Cygni profiles. Additionally, Fe II, O I, He I, and Ca II are detected. The spectra show little evolution with time and with intermediate-width features becoming progressively more prominent, indicating stronger interaction of the SN ejecta with the circumstellar medium. The inspection of archival images from the Panoramic Survey Telescope and Rapid Response System (Pan-STARRS) survey has revealed a variable source at the SN position with a brightest detection in December 2015 at M-r = -14.66 +/- 0.17 mag. This was likely an eruptive phase from the massive progenitor star that started from at least mid-2011, and that produced the circumstellar environment within which the star exploded as a Type IIn SN. The overall properties of SN 2018cnf closely resemble those of transients such as SN 2009ip. This similarity favours a massive hypergiant, perhaps a luminous blue variable, as progenitor for SN 2018cnf.
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8. |
- Kupfer, T., et al.
(författare)
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The OmegaWhite Survey for Short-period Variable Stars. V. Discovery of an Ultracompact Hot Subdwarf Binary with a Compact Companion in a 44-minute Orbit
- 2017
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 851:1
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Tidskriftsartikel (refereegranskat)abstract
- We report the discovery of the ultracompact hot subdwarf (sdOB) binary OW J074106.0-294811.0 with an orbital period of P-orb = 44.66279 +/- 1.16 x 10(-4) minutes, making it the most compact hot subdwarf binary known. Spectroscopic observations using the VLT, Gemini and Keck telescopes revealed a He-sdOB primary with an intermediate helium abundance, T-eff = 39 400 +/- 500 K and log g = 5.74 +/- 0.09. High signal-to-noise ratio light curves show strong ellipsoidal modulation resulting in a derived sdOB mass M-sdOB= 0.23 +/- 0.12 M-circle dot with a WD companion (M-WD = 0.72 +/- 0.17 M-circle dot). The mass ratio was found to be q = M-sdOB/M-WD = 0.32 +/- 0.10. The derived mass for the He-sdOB is inconsistent with the canonical mass for hot subdwarfs of approximate to 0.47 M-circle dot. To put constraints on the structure and evolutionary history of the sdOB star we compared the derived T-eff, log g, and sdOB mass to evolutionary tracks of helium stars and helium white dwarfs calculated with Modules for Experiments in Stellar Astrophysics (MESA). We find that the best-fitting model is a helium white dwarf with a mass of 0.320 M-circle dot, which left the common envelope approximate to 1.1 Myr ago, which is consistent with the observations. As a helium white dwarf with a massive white dwarf companion, the object will reach contact in 17.6 Myr at an orbital period of 5 minutes. Depending on the spin-orbit synchronization timescale the object will either merge to form an R CrB star or end up as a stably accreting AM CVn-type system with a helium white dwarf donor.
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9. |
- Pastorello, A., et al.
(författare)
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The evolution of luminous red nova AT 2017jfs in NGC 4470
- 2019
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Ingår i: Astronomy and Astrophysics. - : EDP SCIENCES S A. - 0004-6361 .- 1432-0746. ; 625
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Tidskriftsartikel (refereegranskat)abstract
- We present the results of our photometric and spectroscopic follow-up of the intermediate-luminosity optical transient AT 2017jfs. At peak, the object reaches an absolute magnitude of M-g = 15.46 +/- 0.15 mag and a bolometric luminosity of 5.5 x 10(41) erg s(-1). Its light curve has the double-peak shape typical of luminous red novae (LRNe), with a narrow first peak bright in the blue bands, while the second peak is longer-lasting and more luminous in the red and near-infrared (NIR) bands. During the first peak, the spectrum shows a blue continuum with narrow emission lines of H and Fe II. During the second peak, the spectrum becomes cooler, resembling that of a K-type star, and the emission lines are replaced by a forest of narrow lines in absorption. About 5 months later, while the optical light curves are characterized by a fast linear decline, the NIR ones show a moderate rebrightening, observed until the transient disappears in solar conjunction. At these late epochs, the spectrum becomes reminiscent of that of M-type stars, with prominent molecular absorption bands. The late-time properties suggest the formation of some dust in the expanding common envelope or an IR echo from foreground pre-existing dust. We propose that the object is a common-envelope transient, possibly the outcome of a merging event in a massive binary, similar to NGC4490-2011OT1.
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10. |
- Xu, D., et al.
(författare)
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DISCOVERY OF THE BROAD-LINED TYPE Ic SN 2013cq ASSOCIATED WITH THE VERY ENERGETIC GRB 130427A
- 2013
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Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 776:2, s. 98-
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Tidskriftsartikel (refereegranskat)abstract
- Long-duration gamma-ray bursts (GRBs) at z < 1 are found in most cases to be accompanied by bright, broadlined Type Ic supernovae (SNe Ic-BL). The highest-energy GRBs are mostly located at higher redshifts, where the associated SNe are hard to detect observationally. Here, we present early and late observations of the optical counterpart of the very energetic GRB 130427A. Despite its moderate redshift, z = 0.3399+/-0.0002, GRB 130427A is at the high end of the GRB energy distribution, with an isotropic-equivalent energy release of E-iso similar to 9.6 x 10(53) erg, more than an order of magnitude more energetic than other GRBs with spectroscopically confirmed SNe. In our dense photometric monitoring, we detect excess flux in the host-subtracted r-band light curve, consistent with that expected from an emerging SN, similar to 0.2 mag fainter than the prototypical SN 1998bw. A spectrum obtained around the time of the SN peak (16.7 days after the GRB) reveals broad undulations typical of SNe Ic-BL, confirming the presence of an SN, designated SN 2013cq. The spectral shape and early peak time are similar to those of the high expansion velocity SN 2010bh associated with GRB 100316D. Our findings demonstrate that high-energy, long-duration GRBs, commonly detected at high redshift, can also be associated with SNe Ic-BL, pointing to a common progenitor mechanism.
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11. |
- Cano, Z., et al.
(författare)
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GRB 161219B/SN 2016jca : A low-redshift gamma-ray burst supernova powered by radioactive heating
- 2017
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 605
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Tidskriftsartikel (refereegranskat)abstract
- Since the first discovery of a broad-lined type Ic supernova (SN) with a long-duration gamma-ray burst (GRB) in 1998, fewer than fifty GRB-supernovae (SNe) have been discovered. The intermediate-luminosity Swift GRB 161219B and its associated supernova SN 2016jca, which occurred at a redshift of z = 0.1475, represents only the seventh GRB-SN to have been discovered within 1 Gpc, and hence provides an excellent opportunity to investigate the observational and physical properties of these very elusive and rare type of SN. As such, we present optical to near-infrared photometry and optical spectroscopy of GRB 161219B and SN 2016jca, spanning the first three months since its discovery. GRB 161219B exploded in the disk of an edge-on spiral galaxy at a projected distance of 3.4 kpc from the galactic centre. GRB 161219B itself is an outlier in the E-p,E-i - E-gamma,E-iso plane, while SN 2016jca had a rest-frame, peak absolute V-band magnitude of M-V = -19.0 +/- 0.1, which it reached after 12.3 +/- 0.7 rest-frame days. We find that the bolometric properties of SN 2016jca are inconsistent with being powered solely by a magnetar central engine, and demonstrate that it was likely powered exclusively by energy deposited by the radioactive decay of nickel and cobalt into their daughter products, which were nucleosynthesised when its progenitor underwent core collapse. We find that 0.22 +/- 0.08 M-circle dot of nickel is required to reproduce the peak luminosity of SN 2016jca, and we constrain an ejecta mass of 5.8 +/- 0.3 M-circle dot and a kinetic energy of 5.1 +/- 0.8 x 10(52) erg. Finally, we report on a chromatic, pre-maximum bump in the g-band light curve, and discuss its possible origin.
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12. |
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13. |
- Lévy, Romain, et al.
(författare)
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Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency.
- 2023
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Ingår i: The Journal of experimental medicine. - : Rockefeller University Press. - 1540-9538 .- 0022-1007. ; 220:2
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Tidskriftsartikel (refereegranskat)abstract
- Patients with inherited CARMIL2 or CD28 deficiency have defective T cell CD28 signaling, but their immunological and clinical phenotypes remain largely unknown. We show that only one of three CARMIL2 isoforms is produced and functional across leukocyte subsets. Tested mutant CARMIL2 alleles from 89 patients and 52 families impair canonical NF-κB but not AP-1 and NFAT activation in T cells stimulated via CD28. Like CD28-deficient patients, CARMIL2-deficient patients display recalcitrant warts and low blood counts of CD4+ and CD8+ memory T cells and CD4+ TREGs. Unlike CD28-deficient patients, they have low counts of NK cells and memory B cells, and their antibody responses are weak. CARMIL2 deficiency is fully penetrant by the age of 10 yr and is characterized by numerous infections, EBV+ smooth muscle tumors, and mucocutaneous inflammation, including inflammatory bowel disease. Patients with somatic reversions of a mutant allele in CD4+ T cells have milder phenotypes. Our study suggests that CARMIL2 governs immunological pathways beyond CD28.
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14. |
- Villarroel, Brian, et al.
(författare)
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The VASCO project : 100 red transients and their follow up
- 2020
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Ingår i: Proceedings of the International Astronautical Congress, IAC. - : International Astronautical Federation, IAF.
-
Konferensbidrag (refereegranskat)abstract
- The Vanishing & Appearing Sources during a Century of Observations (VASCO) project investigates astronomical surveys spanning a 70 years time interval, searching for unusual and exotic transients. We present herein the VASCO Citizen Science Project, that uses three different approaches to the identification of unusual transients in a given set of candidates: hypothesis-driven, exploratory-driven and machine learning-driven (which is of particular benefit for SETI searches). To address the big data challenge, VASCO combines methods from the Virtual Observatory, a user-aided machine learning and visual inspection through citizen science. In this article, we demonstrate the citizen science project, the new and improved candidate selection process and give a progress report. We also present the VASCO citizen science network led by amateur astronomy associations mainly located in Algeria, Cameroon and Nigeria. At the moment of writing, the citizen science project has carefully examined 12,000 candidate image pairs in the data, and has so far identified 713 objects classified as “vanished”. The most interesting candidates will be followed up with optical and infrared imaging, together with the observations by the most potent radio telescopes.
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15. |
- Brimacombe, J., et al.
(författare)
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Supernova 2011fc = Psn J23013638+3220069
- 2011
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Ingår i: Central Bureau Electronic Telegrams. ; 2788, s. 2-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- CBET 2788 available at Central Bureau for Astronomical Telegrams.
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16. |
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17. |
- Fynbo, J. P. U., et al.
(författare)
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The galaxy counterpart and environment of the dusty damped Lyman-α absorber at z = 2.226 towards Q 1218+0832
- 2023
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Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 679
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Tidskriftsartikel (refereegranskat)abstract
- We report on further observations of the field of the quasar Q 1218+0832. Geier et al. (2019, A&A, 625, L9) presented the discovery of the quasar resulting from a search for quasars reddened and dimmed by dust in foreground damped Lyman-α absorbers (DLAs). The DLA is remarkable by having a very large H I column density close to 1022 cm−2. Its dust extinction curve shows the 2175 Å bump known from the Local Group. It also shows absorption from cold gas exemplified by C I and CO molecules. For this paper, we present narrow-band observations of the field of Q 1218+0832 and also use an archival Hubble Space Telescope (HST) image to search for the galaxy counterpart of the DLA. No emission from the DLA galaxy is found in either the narrow-band imaging or in the HST image. In the HST image, we could probe down to an impact parameter of 0.3 arcsec and a 3-σ detection limit of 26.8 mag per arcsec2. In the narrow-band image, we probed down to a 0 arcsec impact parameter and detected nothing down to a 3-σ detection limit of about 3 × 10−17 erg s−1 cm−2. We did detect a bright Lyman-α emitter 59 arcsec south of Q 1218+0832 with a flux of 3 × 10−16 erg s−1 cm−2. We conclude that the DLA galaxy must be located at a very small impact parameter (< 0.3 arcsec, 2.5 kpc) or it is optically dark. Also, the DLA galaxy most likely is part of a galaxy group.
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18. |
- Gandolfi, D., et al.
(författare)
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Kepler-423b: a half-Jupiter mass planet transiting a very old solar-like star
- 2015
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 576
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Tidskriftsartikel (refereegranskat)abstract
- We report the spectroscopic confirmation of the Kepler object of interest KOI-183.01 (Kepler-423b), a half-Jupiter mass planet transiting an old solar-like star every 2.7 days. Our analysis is the first to combine the full Kepler photometry (quarters 1 17) with high-precision radial velocity measurements taken with the FIES spectrograph at the Nordic Optical Telescope. We simultaneously modelled the photometric and spectroscopic data-sets using Bayesian approach coupled with Markov chain Monte Carlo sampling. We found that the Kepler pre-search data conditioned light curve of Kepler-423 exhibits quarter-to-quarter systematic variations of the transit depth, with a peak-to-peak amplitude of similar to 4.3% and seasonal trends reoccurring every four quarters. We attributed these systematics to an incorrect assessment of the quarterly variation of the crowding metric. The host star Kepler-423 is a G4 dwarf with M-* = 0.85 +/- 0.04 M-circle dot, R-* = 0.95 +/- 0.04 R-circle dot, T-eff = 5560 +/- 80 K, [M/H] = -0.10 +/- 0.05 dex, and with an age of 11 +/- 2 Gyr. The planet Kepler-423b has a mass of M-p = 0.595 +/- 0.081 M-Jup and a radius of R-p = 1.192 +/- 0.052 R-Jup, yielding a planetary bulk density of rho(p) = 0.459 +/- 0.083 g cm(-3). The radius of Kepler-423b is consistent with both theoretical models for irradiated coreless giant planets and expectations based on empirical laws. The inclination of the stellar spin axis suggests that the system is aligned along the line of sight. We detected a tentative secondary eclipse of the planet at a 2 sigma confidence level (Delta F-ec = 14.2 +/- 6.6 ppm) and found that the orbit might have a small non-zero eccentricity of 0.019(-0.014)(+0.028) . With a Bond albedo of A(B) = 0.037 +/- 0.019, Kepler-423b is one of the gas-giant planets with the lowest albedo known so far.
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19. |
- Latour, M., et al.
(författare)
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Quantitative spectral analysis of the sdB star HD188112 : A helium-core white dwarf progenitor
- 2016
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 585
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Tidskriftsartikel (refereegranskat)abstract
- Context. HD 188112 is a bright (V = 10 : 2 mag) hot subdwarf B (sdB) star with a mass too low to ignite core helium burning and is therefore considered a pre-extremely low-mass (ELM) white dwarf (WD). ELM WDs (M less than or similar to 0.3 M-circle dot) are He-core objects produced by the evolution of compact binary systems. Aims. We present in this paper a detailed abundance analysis of HD188112 based on high-resolution Hubble Space Telescope (HST) near-and far-ultraviolet spectroscopy. We also constrain the mass of the star's companion. Methods. We use hybrid non-LTE model atmospheres to fit the observed spectral lines, and to derive the abundances of more than a dozen elements and the rotational broadening of metallic lines. Results. We confirm the previous binary system parameters by combining radial velocities measured in our UV spectra with the previously published values. The system has a period of 0.60658584 days and a WD companion with M >= 0.70 M-circle dot. By assuming a tidally locked rotation combined with the projected rotational velocity (v sin i = 7.9 +/- 0.3 km s(-1)), we constrain the companion mass to be between 0.9 and 1.3 M-circle dot. We further discuss the future evolution of the system as a potential progenitor of an underluminous type Ia supernova. We measure abundances for Mg, Al, Si, P, S, Ca, Ti, Cr, Mn, Fe, Ni, and Zn, and for the trans-iron elements Ga, Sn, and Pb. In addition, we derive upper limits for the C, N, O elements and find HD188112 to be strongly depleted in carbon. We find evidence of non-LTE e ff ects on the line strength of some ionic species such as Si II and Ni II. The metallic abundances indicate that the star is metal-poor, with an abundance pattern most likely produced by diffusion effects.
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20. |
- Sebastian, D., et al.
(författare)
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Sub-stellar companions of intermediate-mass stars with CoRoT: CoRoT-34b, CoRoT-35b, and CoRoT-36b
- 2022
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 516:1, s. 636-655
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Tidskriftsartikel (refereegranskat)abstract
- Theories of planet formation give contradicting results of how frequent close-in giant planets of intermediate mass stars (IMSs; 1.3 <= M-* <= 3.2 M-circle dot) are. Some theories predict a high rate of IMSs with close-in gas giants, while others predict a very low rate. Thus, determining the frequency of close-in giant planets of IMSs is an important test for theories of planet formation. We use the CoRoT survey to determine the absolute frequency of IMSs that harbour at least one close-in giant planet and compare it to that of solar-like stars. The CoRoT transit survey is ideal for this purpose, because of its completeness for gas-giant planets with orbital periods of less than 10 d and its large sample of main-sequence IMSs. We present a high precision radial velocity follow-up programme and conclude on 17 promising transit candidates of IMSs, observed with CoRoT. We report the detection of CoRoT-34b, a brown dwarf close to the hydrogen burning limit, orbiting a 1.1 Gyr A-type main-sequence star. We also confirm two inflated giant planets, CoRoT-35b, part of a possible planetary system around a metal-poor star, and CoRoT-36b on a misaligned orbit. We find that 0.12 +/- 0.10 per cent of IMSs between 1.3 <= M-* <= 1.6 M-circle dot observed by CoRoT do harbour at least one close-in giant planet. This is significantly lower than the frequency (0.70 +/- 0.16 per cent) for solar-mass stars, as well as the frequency of IMSs harbouring long-period planets (similar to 8 per cent).
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23. |
- de Lange, Charlotte, 1963, et al.
(författare)
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Hepatic magnetic resonance T1-mapping and extracellular volume fraction compared to shear-wave elastography in pediatric Fontan-associated liver disease
- 2021
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Ingår i: Pediatric Radiology. - : Springer Science and Business Media LLC. - 0301-0449 .- 1432-1998. ; 51:1, s. 66-76
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Tidskriftsartikel (refereegranskat)abstract
- Background: Children with Fontan circulation are at risk of developing hepatic fibrosis/cirrhosis. Reliable noninvasive monitoring techniques are lacking or under development. Objective: To investigate surrogate indicators of hepatic fibrosis in adolescents with Fontan circulation by evaluating hepatic magnetic resonance (MR) T1 mapping and extracellular volume fraction measurements compared to US shear-wave elastography. Materials and methods: We analyzed hepatic native T1 times and extracellular volume fractions with modified Look-Locker inversion recovery. Liver stiffness was analyzed with shear-wave elastography. We compared results between 45 pediatric patients ages 16.7±0.6 years with Fontan circulation and 15 healthy controls ages 19.2±1.2 years. Measurements were correlated to clinical and hemodynamic data from cardiac catheterization. Results: MR mapping was successful in 35/45 patients, revealing higher hepatic T1 times (774±44 ms) than in controls (632±52 ms; P<0.001) and higher extracellular volume fractions (47.4±5.0%) than in controls (34.6±3.8%; P<0.001). Liver stiffness was 1.91±0.13 m/s in patients vs. 1.20±0.10 m/s in controls (P<0.001). Native T1 times correlated with central venous pressures (r=0.5, P=0.007). Native T1 was not correlated with elastography in patients (r=0.2, P=0.1) or controls (r = −0.3, P=0.3). Extracellular volume fraction was correlated with elastography in patients (r=0.5, P=0.005) but not in controls (r=0.2, P=0.6). Conclusion: Increased hepatic MR relaxometry and shear-wave elastography values in adolescents with Fontan circulation suggested the presence of hepatic fibrosis or congestion. Central venous pressure was related to T1 times. Changes were detected differently with MR relaxometry and elastography; thus, these techniques should not be used interchangeably in monitoring hepatic fibrosis.
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24. |
- Fynbo, J. P. U., et al.
(författare)
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On the two high-metallicity DLAs at z=2.412 and 2.583 towards Q 0918+1636
- 2013
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 436:1, s. 361-370
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Tidskriftsartikel (refereegranskat)abstract
- The quasar Q0918+1636 (z = 3.07) has two intervening high-metallicity Damped Lyman a Absorbers (DLAs) along the line of sight, at redshifts of z = 2.412 and 2.583. The z = 2.583 DLA is located at a large impact parameter of 16.2 kpc, and despite this large impact parameter it has a very high metallicity (consistent with solar), a substantial fraction of H-2 molecules and it is dusty as inferred from the reddened spectrum of the background QSO. The z = 2.412 DLA has a metallicity of [M/H] = -0.6 (based on Zn II and Si II). In this paper we present new observations of this interesting sightline consisting of deep multiband imaging and further VLT spectroscopy. By fitting stellar population synthesis models to the photometric Spectral Energy Distribution we constrain the physical properties of the z = 2.583 DLA galaxy, and we infer its morphology by fitting a Sersic model to its surface brightness profile. We find it to be a relatively massive (M-* approximate to 10(10) M-circle dot), strongly star-forming (SFR approximate to 30 M-circle dot yr(-1)), dusty (E(B - V) = 0.4) galaxy with a disc-like morphology. We detect strong emission lines from the z = 2.583 DLA ([O II] lambda 3727, [O III] lambda lambda 4960, 5007, H beta and H alpha, albeit at low signal-to-noise ratio except for the [O III] lambda 5007 line). The metallicity derived from the emission lines is consistent with the absorption metallicity (12 + log (O/H) = 8.8 +/- 0.2). We also detect [O III] lambda 5007 emission from the galaxy counterpart of the z = 2.412 DLA at a small impact parameter (<2 kpc). Overall our findings are consistent with the emerging picture that high-metallicity DLAs are associated with relatively luminous and massive galaxy counterparts, compared to typical DLAs.
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25. |
- Hohn, Nuri, et al.
(författare)
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Amphiphilic diblock copolymer-mediated structure control in nanoporous germanium-based thin films
- 2019
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Ingår i: Nanoscale. - : ROYAL SOC CHEMISTRY. - 2040-3364 .- 2040-3372. ; 11:4, s. 2048-2055
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Tidskriftsartikel (refereegranskat)abstract
- Fabrication of porous, foam-like germanium-based (Ge-based) nanostructures is achieved with the use of the amphiphilic diblock copolymer polystyrene-b-polyethylene oxide as structure directing agent. Basic concepts of block copolymer assisted sol-gel synthesis are successfully realized based on the [Ge-9](4-) Zintl clusters as a precursor for Ge-based thin films. Material/elemental composition and crystalline Ge-based phases are investigated via X-ray photoelectron spectroscopy and X-ray diffraction measurements, respectively. Poor-good solvent pair induced phase separation leads to pore sizes in the Ge-based films up to 40 nm, which can be tuned through a change of the molar mixing ratio between polymer template and precursor as proven by grazing incidence small angle X-ray scattering and scanning electron microscopy.
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29. |
- Maccari, Maria Elena, et al.
(författare)
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Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity.
- 2023
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Ingår i: The Journal of allergy and clinical immunology. - 1097-6825. ; 152:4
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Tidskriftsartikel (refereegranskat)abstract
- Activated phosphoinositide-3-kinase δ syndrome (APDS) is an inborn error of immunity (IEI) with infection susceptibility and immune dysregulation, clinically overlapping with other conditions. Management depends on disease evolution, but predictors of severe disease are lacking.This study sought to report the extended spectrum of disease manifestations in APDS1 versus APDS2; compare these to CTLA4 deficiency, NFKB1 deficiency, and STAT3 gain-of-function (GOF) disease; and identify predictors of severity in APDS.Data was collected from the ESID (European Society for Immunodeficiencies)-APDS registry and was compared with published cohorts of the other IEIs.The analysis of 170 patients with APDS outlines high penetrance and early onset of APDS compared to the other IEIs. The large clinical heterogeneity even in individuals with the same PIK3CD variant E1021K illustrates how poorly the genotype predicts the disease phenotype and course. The high clinical overlap between APDS and the other investigated IEIs suggests relevant pathophysiological convergence of the affected pathways. Preferentially affected organ systems indicate specific pathophysiology: bronchiectasis is typical of APDS1; interstitial lung disease and enteropathy are more common in STAT3 GOF and CTLA4 deficiency. Endocrinopathies are most frequent in STAT3 GOF, but growth impairment is also common, particularly in APDS2. Early clinical presentation is a risk factor for severe disease in APDS.APDS illustrates how a single genetic variant can result in a diverse autoimmune-lymphoproliferative phenotype. Overlap with other IEIs is substantial. Some specific features distinguish APDS1 from APDS2. Early onset is a risk factor for severe disease course calling for specific treatment studies in younger patients.
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30. |
- Moltu, Sissel J., et al.
(författare)
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Arachidonic and docosahexaenoic acid supplementation and brain maturation in preterm infants : a double blind RCT
- 2024
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Ingår i: Clinical Nutrition. - : Elsevier. - 0261-5614 .- 1532-1983. ; 43:1, s. 176-186
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Tidskriftsartikel (refereegranskat)abstract
- Background: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are important structural components of neural cellular membranes and possess anti-inflammatory properties. Very preterm infants are deprived of the enhanced placental supply of these fatty acids, but the benefit of postnatal supplementation on brain development is uncertain. The aim of this study was to test the hypothesis that early enteral supplementation with ARA and DHA in preterm infants improves white matter (WM) microstructure assessed by diffusion-weighted MRI at term equivalent age.Methods: In this double-blind, randomized controlled trial, infants born before 29 weeks gestational age were allocated to either 100 mg/kg ARA and 50 mg/kg DHA (ARA:DHA group) or medium chain triglycerides (control). Supplements were started on the second day of life and provided until 36 weeks postmenstrual age. The primary outcome was brain maturation assessed by diffusion tensor imaging (DTI) using Tract-Based Spatial Statistics (TBSS) analysis.Results: We included 120 infants (60 per group) in the trial; mean (range) gestational age was 26+3 (22+6 - 28+6) weeks and postmenstrual age at scan was 41+3 (39+1 - 47+0) weeks. Ninety-two infants underwent MRI imaging, and of these, 90 had successful T1/T2 weighted MR images and 74 had DTI data of acceptable quality. TBSS did not show significant differences in mean or axial diffusivity between the groups, but demonstrated significantly higher fractional anisotropy in several large WM tracts in the ARA:DHA group, including corpus callosum, the anterior and posterior limb of the internal capsula, inferior occipitofrontal fasciculus, uncinate fasciculus, and the inferior longitudinal fasciculus. Radial diffusivity was also significantly lower in several of the same WM tracts in the ARA:DHA group.Conclusion: This study suggests that supplementation with ARA and DHA at doses matching estimated fetal accretion rates improves WM maturation compared to control treatment, but further studies are needed to ascertain any functional benefit.Clinical trial registration: www.clinicaltrials.gov; ID:NCT03555019.
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33. |
- Pipinato, A., et al.
(författare)
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Prolonging the service life of steel truss bridges
- 2018
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Ingår i: Maintenance, Safety, Risk, Management and Life-Cycle Performance of Bridges. - : Taylor & Francis. ; , s. 489-496
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Konferensbidrag (refereegranskat)abstract
- Prolonging the life of existing steel trusses all over the world is a incoming necessity for all managing authorities wherever these structures have reached a particular state of use. The unsatisfactory behavior of these structures under the current type and increasing number of loads make clearer that innovative solutions are needed. For this purpose, the realization of different techniques are presented, in order to retrofit the actual load onto a structure conceived with historical codes, characterized by lower design live loads. The possibilities of retrofitting bridges with different solution studied in a recent research program are presented and compared in this study.
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34. |
- Pipinato, A., et al.
(författare)
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Steel bridge structural retrofit : Innovative and light-weight solutions
- 2018
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Ingår i: Life Cycle Analysis and Assessment in Civil Engineering: Towards an Integrated Vision. - : Taylor & Francis. ; , s. 2857-2867
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Konferensbidrag (refereegranskat)abstract
- Prolonging the life of existing steel trusses all over the world is a incoming necessity for all managing authorities wherever these structures have reached a particular state of use. The unsatisfactory behavior of these structures under the current type and increasing number of loads make clearer that innovative solutions are needed. For this purpose, the realization of different techniques are presented, in order to retrofit the actual load onto a structure conceived with historical codes, characterized by lower design live loads. The possibilities of retrofitting bridges with different solution studied in a recent research program are presented and compared in this study.
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35. |
- Pipinato, A., et al.
(författare)
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UHPFRC strengthening strategies on existing steel and steel-concrete bridges
- 2021
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Ingår i: Bridge Maintenance, Safety, Management, Life-Cycle Sustainability and Innovations. - : CRC Press. ; , s. 598-605
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Konferensbidrag (refereegranskat)abstract
- The overall traffic density and the allowed vehicle weights have been increasing over the last decades. As a response, new roads and railway lines are continuously planned and built. On the other hand, the existing bridges must also be capable of dealing with the increasing traffic volume and the increasing vehicle weights. Many existing bridges were not originally designed for the high traffic loads and todays traffic volume. To cope with the increased loads and load frequencies, the aged structures need repair and strengthening. To avoid the replacement of existing structures, the overall objective is to improve the structural performance of existing steel and steel-concrete bridges by providing innovative and well documented repair and strengthening solutions to bridge designers and road/railway-administrations in Europe. In this paper the use of UHPFRC as a solution for bridge and viaduct repair and strengthening has been presented.
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36. |
- Poidevin, F., et al.
(författare)
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Optical polarization and spectral properties of the hydrogen-poor superluminous supernovae SN 2021bnw and SN 2021fpl
- 2023
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 521:4, s. 5418-5439
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Tidskriftsartikel (refereegranskat)abstract
- New optical photometric, spectroscopic, and imaging polarimetry data are combined with publicly available data to study some of the physical properties of the two hydrogen-poor superluminous supernovae (SLSNe) SN 2021bnw and SN 2021fpl. For each SLSN, the best-fitting parameters obtained from the magnetar model with Modular Open-Source Fitter for Transients do not depart from the range of parameter obtained on other SLSNe discussed in the literature. A spectral analysis with SYN++ shows that SN 2021bnw is a W type, fast evolver, while SN 2021fpl is a 15bn type, slow evolver. The analysis of the polarimetry data obtained on SN 2021fpl at four epochs (+1.8, +20.6, +34.1, and +43.0 d, rest frame) shows >3σ polarization detections in the range of 0.8–1 per cent. A comparison of the spectroscopy data suggests that SN 2021fpl underwent a spectral transition a bit earlier than SN 2015bn, during which, similarly, it could have underwent a polarization transition. The analysis of the polarimetry data obtained on SN 2021bnw does not show any departure from symmetry of the photosphere at an empirical diffusion time-scale of ≈2 (+81.1 d rest frame). This result is consistent with those on the sample of W-type SLSN observed at empirical diffusion time-scale ≤ 1 with that technique, even though it is not clear the effect of limited spectral windows varying from one object to the other. Measurements at higher empirical diffusion time-scale may be needed to see any departure from symmetry as it is discussed in the literature for SN 2017egm.
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37. |
- Poidevin, F., et al.
(författare)
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Post maximum light and late time optical imaging polarimetry of type I superluminous supernova 2020znr
- 2022
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 511:4, s. 5948-5963
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Tidskriftsartikel (refereegranskat)abstract
- Optical imaging polarimetry was conducted on the hydrogen poor superluminous supernova 2020znr during three phases after maximum light (approximate to +34 d, +288 d, and +289 d). After instrumental and interstellar polarization correction, all measurements are consistent with null-polarization detection. Modelling the light curve with a magnetar spin-down model shows that SN2020znr has similar magnetar and ejecta parameters to other SLSNe. A comparison of the best-fitting values discussed in the literature on SN 2017egm and SN 2015bn, two hydrogen poor SLSNe showing an increase of polarization after maximum light, suggests that SN 2020znr has higher mass ejecta that may prevent access to the geometry of the inner ejecta with optical polarimetry. The combined information provided by spectroscopy and light-curve analysis of type I SLSNe may be an interesting avenue to categorize the polarization properties of this class of transients. This approach would require to expand the sample of SLSNe polarimetry data currently available with early and late time epochs new measurements.
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38. |
- Purucker, E, et al.
(författare)
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Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids
- 2002
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Ingår i: American journal of physiology. Renal physiology. - : American Physiological Society. - 1931-857X .- 1522-1466. ; 283:6, s. F1281-F1289
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Tidskriftsartikel (refereegranskat)abstract
- Hepatic synthesis and plasma levels of glutathione are markedly decreased in chronic liver disease. Because glutathione turnover is highest in kidneys, we examined whether changes in kidney glutathione occur in chronic cholestasis and whether they are related to kidney dysfunction in liver disease. Kidney and plasma GSH and GSSG were measured 1) in bile duct-ligated (BDL) rats; 2) in healthy rats after bile acid loading to mimic cholestasis; and 3) after irreversible inhibition of glutathione synthetase with buthionine-sulfoximine (BSO), where glutathione consumption, urinary volume, and sodium excretion were also estimated. In addition, γ-glutamylcysteine synthetase (γ-GCS) mRNA, protein, and enzymatic specific activity were measured in kidney tissue after BDL. After BDL, kidney GSH and GSSG increased within hours by 67 and 66%, respectively. The increases were not related to plasma glutathione, which decreased below control values. Intravenous bile acid loading caused identical increases in GSH and GSSG as occurred after BDL, when glycine- or taurine-conjugated dihydroxy bile acids were administered. Glutathione consumption, as estimated after blocking of de novo synthesis with BSO, was significantly increased after BDL (127 vs. 44 nmol · g−1· min−1). γ-GCS mRNA and enzymatic specific activity were significantly reduced 5 days after BDL, whereas protein concentrations did not change. The urinary sodium concentration was 70% lower in BDL than in control rats. Depletion of renal glutathione normalized sodium excretion by increasing urinary sodium concentration and urinary volume. The increase in kidney glutathione after BDL seems to be mediated by an increase in plasma bile acids and is critically related to sodium retention. The increase in GSH consumption despite reduced γ-GCS activity indicates a decreased GSH turnover tentatively due to reduced renal GSH efflux by competition with organic anions at membrane transport proteins.
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39. |
- Villarroel, Beatriz, et al.
(författare)
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Launching the VASCO Citizen Science Project
- 2022
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Ingår i: Universe. - : MDPI AG. - 2218-1997. ; 8:11, s. 561-
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Tidskriftsartikel (refereegranskat)abstract
- The Vanishing & Appearing Sources during a Century of Observations (VASCO) project investigates astronomical surveys spanning a time interval of 70 years, searching for unusual and exotic transients. We present herein the VASCO Citizen Science Project, which can identify unusual candidates driven by three different approaches: hypothesis, exploratory, and machine learning, which is particularly useful for SETI searches. To address the big data challenge, VASCO combines three methods: the Virtual Observatory, user-aided machine learning, and visual inspection through citizen science. Here we demonstrate the citizen science project and its improved candidate selection process, and we give a progress report. We also present the VASCO citizen science network led by amateur astronomy associations mainly located in Algeria, Cameroon, and Nigeria. At the moment of writing, the citizen science project has carefully examined 15,593 candidate image pairs in the data (ca. 10% of the candidates), and has so far identified 798 objects classified as "vanished". The most interesting candidates will be followed up with optical and infrared imaging, together with the observations by the most potent radio telescopes.
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