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- Erosa-Rejon, Gilda J., et al.
(författare)
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Benzochromenes from the roots of Bourreria pulchra
- 2010
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Ingår i: Phytochemistry Letters. - : Elsevier BV. - 1874-3900. ; 3:1, s. 9-12
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Tidskriftsartikel (refereegranskat)abstract
- Two new benzochromenes, (6,6-dimethyl-2-methoxy-6H-benzo[c]chromen-9-yl)methanol (1), and 2-methoxy-6,6-dimethyl-6H-benzo[c]chromen-9-carbaldehyde (2), together with several already known metabolites, were isolated from the root extract of Bourreria pulchra (Boraginaceae). The structures of 1 and 2 were established on the basis of their spectroscopic data. Both were assayed for in vitro antiprotozoan activity, and especially 1 was found to possess significant activity against Leishmania mexicana and Trypanosoma cruzi parasites (IC50 4.6 mu g/mL and 7.5 mu g/mL, respectively). (C) 2009 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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