| 1. |
- Santangelo, James S., et al.
(författare)
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Global urban environmental change drives adaptation in white clover
- 2022
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 375
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Tidskriftsartikel (refereegranskat)abstract
- Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural dines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale.
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| 3. |
- Tjernström, Michael, et al.
(författare)
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The Arctic Summer Cloud Ocean Study (ASCOS) : overview and experimental design
- 2014
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Ingår i: Atmospheric Chemistry And Physics. - : Copernicus GmbH. - 1680-7316 .- 1680-7324. ; 14:6, s. 2823-2869
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Tidskriftsartikel (refereegranskat)abstract
- The climate in the Arctic is changing faster than anywhere else on earth. Poorly understood feedback processes relating to Arctic clouds and aerosol-cloud interactions contribute to a poor understanding of the present changes in the Arctic climate system, and also to a large spread in projections of future climate in the Arctic. The problem is exacerbated by the paucity of research-quality observations in the central Arctic. Improved formulations in climate models require such observations, which can only come from measurements in situ in this difficult-to-reach region with logistically demanding environmental conditions. The Arctic Summer Cloud Ocean Study (ASCOS) was the most extensive central Arctic Ocean expedition with an atmospheric focus during the International Polar Year (IPY) 2007-2008. ASCOS focused on the study of the formation and life cycle of low-level Arctic clouds. ASCOS departed from Longyearbyen on Svalbard on 2 August and returned on 9 September 2008. In transit into and out of the pack ice, four short research stations were undertaken in the Fram Strait: two in open water and two in the marginal ice zone. After traversing the pack ice northward, an ice camp was set up on 12 August at 87 degrees 21' N, 01 degrees 29' W and remained in operation through 1 September, drifting with the ice. During this time, extensive measurements were taken of atmospheric gas and particle chemistry and physics, mesoscale and boundary-layer meteorology, marine biology and chemistry, and upper ocean physics. ASCOS provides a unique interdisciplinary data set for development and testing of new hypotheses on cloud processes, their interactions with the sea ice and ocean and associated physical, chemical, and biological processes and interactions. For example, the first-ever quantitative observation of bubbles in Arctic leads, combined with the unique discovery of marine organic material, polymer gels with an origin in the ocean, inside cloud droplets suggests the possibility of primary marine organically derived cloud condensation nuclei in Arctic stratocumulus clouds. Direct observations of surface fluxes of aerosols could, however, not explain observed variability in aerosol concentrations, and the balance between local and remote aerosols sources remains open. Lack of cloud condensation nuclei (CCN) was at times a controlling factor in low-level cloud formation, and hence for the impact of clouds on the surface energy budget. ASCOS provided detailed measurements of the surface energy balance from late summer melt into the initial autumn freeze-up, and documented the effects of clouds and storms on the surface energy balance during this transition. In addition to such process-level studies, the unique, independent ASCOS data set can and is being used for validation of satellite retrievals, operational models, and reanalysis data sets.
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| 9. |
- Granath, C, et al.
(författare)
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Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women
- 2021
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Ingår i: Open heart. - : BMJ. - 2053-3624. ; 8:2
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Tidskriftsartikel (refereegranskat)abstract
- Determine whether associations between bicuspid aortic valve (BAV) phenotypes, valve disease and aortopathy differ between sexes.Methods1045 patients with BAV (76.0% men, n=794) from two surgical centres were included in this cross-sectional study. Valve phenotype was classified intraoperatively as right–left (RL), right-non-coronary (RN), left-non-coronary (LN) or 2-sinus BAV. Echocardiography was used to determine type and degree of valve disease, and aortic dimensions. Aortic dilatation was defined as diameter ≥4.5 cm.ResultsRL was the most common phenotype (73.6%), followed by RN (16.2%), 2-sinus BAV (9.2%) and LN (1.1%), with no difference in phenotype distribution between men and women (p=0.634). Aortic valve insufficiency (AI) prevalence differed significantly with valve phenotype in men (p=0.047), with RL and LN having the highest prevalence (34.1% and 44.0%, respectively). In women, RN had a higher proportion of AI than RL (21.3% vs 7.3%, p=0.017). Men with RL had larger root dimensions, in particular at the sinus (mean difference 0.24 cm compared with RN, p=0.002). Men with 2-sinus BAV had the highest prevalence of root phenotype dilatation (7.0%, other phenotypes ≤2.3%, p=0.031), whereas women with 2-sinus BAV did not have root dilatation and smaller sinus dimensions (mean difference: 0.35 cm compared with RL, p=0.021). Aortic root segments were larger in men with AI compared with aortic stenosis (sinus mean difference: 0.40 cm, p<0.001). The difference was even larger in women (mean difference: 0.78 cm, p<0.001), and women with AI also had larger tubular segments (mean difference: 0.61 cm, p=0.001).ConclusionsThere are significant sex differences in clinical associations of BAV phenotypes, which should be considered in further studies on the role of phenotypes in individualised patient management.
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| 10. |
- Gronhagen, C. M., et al.
(författare)
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Increased risk of cancer among 3663 patients with cutaneous lupus erythematosus : a Swedish nationwide cohort study
- 2012
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Ingår i: British Journal of Dermatology. - : Oxford University Press (OUP). - 0007-0963 .- 1365-2133. ; 166:5, s. 1053-1059
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Tidskriftsartikel (refereegranskat)abstract
- Background: Other autoimmune diseases have been associated with higher risks for cancer, and numerous case reports of cutaneous lupus erythematosus (CLE) and different cancer types are available. Objectives: To estimate the overall and specific cancer risks in a nationwide cohort study of patients diagnosed with CLE in Sweden and compare that risk with that in a control cohort without CLE. Methods: A cohort of 3663 individuals with CLE and a matched control cohort from the general population (three controls to each CLE case) without a diagnosis of CLE were derived from the Swedish National Patient Register, 1997-2007, and were electronically linked to the Swedish Cancer Register and the Swedish Cause of Death Register. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated to compare the observed vs. the expected numbers of cancers. Results: A total of 183 incident cancers occurred within the observation interval, yielding a HR of 1.8 (95% CI 1.5-2.2) for cancer overall. Median follow-up was 4.1 years. About a fourfold risk increase was seen for buccal cancer, lymphomas, respiratory cancer and nonmelanoma skin cancer. Conclusions: Patients with CLE appear to have an elevated risk for certain cancer types, an increase that remains when excluding patients also diagnosed with systemic lupus erythematosus. Our findings point to the importance of counselling about not smoking and sun avoidance, and underscore the need for specialized monitoring of this patient group along with bench-to-bedside research efforts to clarify pathogenesis.
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| 11. |
- Gronhagen, C. M., et al.
(författare)
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Subacute cutaneous lupus erythematosus and its association with drugs : a population-based matched case-control study of 234 patients in Sweden
- 2012
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Ingår i: British Journal of Dermatology. - : Oxford University Press (OUP). - 0007-0963 .- 1365-2133. ; 167:2, s. 296-305
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Tidskriftsartikel (refereegranskat)abstract
- Background Numerous case reports about drug-induced (DI) subacute cutaneous lupus erythematosus (SCLE) have been published. Various drug types with different latencies has been proposed as triggers for this autoimmune skin disease.Objectives To evaluate the association between exposure to certain suspected drugs (previously implicated to induce SCLE) and a subsequent diagnosis of SCLE.Methods We performed a population-based matched case-control study in which all incident cases of SCLE (n = 234) from 2006 to 2009 were derived from the National Patient Register. The control group was selected from the general population, matched (1 : 10) for gender, age and county of residence. The data were linked to the Prescribed Drug Register. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for the association between exposures to certain suspected drugs and the development of SCLE.Results: During the 6 months preceding SCLE diagnosis, 166 (71%) of the patients with SCLE had at least one filled prescription of the suspected drugs. The most increased ORs were found for terbinafine (OR 52.9, 95% CI 6.6-infinity), tumour necrosis factor-alpha inhibitors (OR 8.0, 95% CI 1.6-37.2), antiepileptics (OR 3.4, 95% CI 1.9-5.8) and proton pump inhibitors (OR 2.9, 95% CI 2.0-4.0).Conclusions: We found an association between drug exposure and SCLE. More than one third of the SCLE cases could be attributed to drug exposure. No significant OR was found for thiazides, which might be due to longer latency and therefore missed with this study design. DI-SCLE is reversible once the drug is discontinued, indicating the importance of screening patients with SCLE for potentially triggering drugs. A causal relationship cannot be established from this study and the underlying pathogenesis remains unclear.
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| 16. |
- Andersson, C A Morgan, 1965, et al.
(författare)
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Aging-in-Place: Residents’ Attitudes and Floor Plan Potential in Apartment Buildings From 1990 to 2015
- 2021
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Ingår i: HERD. - : SAGE Publications. - 2167-5112 .- 1937-5867. ; 14:4, s. 211-226
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: We investigated apartment designs in apartment blocks built 1990-2015 in Gothenburg, Sweden. We investigated the residents' attitudes toward their previous, present, and future housing and their perceived possibilities for aging-in-place. We analyzed their apartments, focusing on the possibilities for aging-in-place in future care situations concerning bedroom capacity in a care situation; spatial proximity between bathroom, bedroom, storage, and entrance; and functional autonomy in a care situation without too much disturbance for a partner. Background: Since the 2000s, the ambition in Sweden is to enable older people to remain in ordinary housing. The possibilities for aging-in-place should therefore be considered already in the design stage, also when producing standard apartments. Methods: Semi-structured interviews were made with 30 households, with one or more resident 65 years or older. Floor plan analyses were made of their present apartments. Results: The majority displayed a pragmatic attitude toward aging, high satisfaction with their present housing situation, and good chances for aging-in-place in future homecare scenarios. The floor plan analysis shows that the three concepts of bedroom capacity, spatial proximity, and functional autonomy can be used to determine the potential for aging-in-place. Conclusions: The results suggest that architectural qualities related to aging-in-place are not automatically connected to floor size or number of rooms. Small apartments can perform better than larger ones, depending on spatio-functional organization and connections between different functions. The residents' perceived chances for aging-in-place confirm this relation. Future studies should compare different locations, production periods, and relations between size, space efficiency, and accessibility.
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| 17. |
- Andersson, C A Morgan, 1965, et al.
(författare)
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Bygglov Göteborg 2017.
- 2022
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- I boken finns samlat beviljade bygglov för flerbostadshus i Göteborg 2017. Författarna analyserar i boken projekten och delat in dem i typer, antal och storlekar. Här beskrivs också tendenser som identifierats i byggloven, exempelvis nya kökstyper som korridorköket och entréköket. Men även planlösningsproblematik med lägenheter där alla sovrum vetter ut mot loftgång och lägenheter med stor andel kommunikationsyta. Boken lyfter också fram de goda exemplen, föredömen, som finns i materialet. Syftet med sammanställningen är att initiera en diskussion om vad som byggs, vilka lägenhetsstorlekar, vilka typer, var i staden nya bostäder byggs, vem som bygger, vilka arkitekter som ritar och vilka arkitekturkvaliteter som framgår av planlösningarna.
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| 18. |
- Andersson, C A Morgan, 1965, et al.
(författare)
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Potential för kvarboende
- 2022
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Ingår i: Bra bostäder för seniorer. - 9789179171537 ; , s. 95-100
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Rapporten sammanfattar en bostadsstudie som genomförts 2017–2020 på Norra Älvstranden i Göteborg. Syftet med projektet har varit att undersöka möjligheterna till kvarboende för äldre personer 65+ i lägenheter byggda cirka 1990–2015. Studiens huvudfråga har varit: – vad krävs av en bostad i ett flerbostadshus för att det ska finnas möjlighet till kvarboende för äldre personer med stora behov av vård och omsorg. Forskningsfrågan är ställd mot bakgrund av utvecklingen av svensk bostadspolitik. Där framgår att bostäder byggda under 2010-talet minskar i storlek, areamässigt. Parallellt finns ambitioner inom vårdsektorn om ökat kvarboende och att bedriva mer vård i hemmet. Möjligheten att göra det är en viktig del i att minska belastningen på sjukhus och vårdcentraler. För att fånga begreppet kvarboende och hushållens attityder har forskargruppen gjort 30 intervjuer med boende i deras hem, som tillsammans med en enkät ger en bra bild över hur bostäderna används.
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| 19. |
- Andersson, C A Morgan, 1965, et al.
(författare)
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Potential för kvarboende. Sovrumskapacitet - rumslig närhet - funktionell autonomi
- 2021
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Den här rapporten sammanfattar en bostadsstudie som genomfördes 2017–2020 på Norra Älvstranden i Göteborg. Syftet med projektet har varit att undersöka möjligheterna till kvarboende för äldre personer i lägenheter byggda 1990–2015. Vad krävs av en bostad i ett flerbostadshus för att det ska finnas möjlighet till kvarboende för äldre personer med stora behov av vård och omsorg? Studiens huvudfråga är ställd mot bakgrund av utvecklingen inom svensk bostadspolitik, där bostäder byggda under 2010-talet har minskat i storlek, areamässigt. Parallellt har vårdsektorn ambitioner att bedriva mer vård i hemmet. Möjligheten att göra det är en viktig del i att minska belastningen på sjukhus och vårdcentraler. För att fånga begreppet kvarboende och hushållens attityder har forskargruppen gjort intervjuer med boende i deras hem, och tillsammans med en enkät ger det en bra bild över hur bostäderna används. Resultatet ringar in tre begrepp som är viktiga för att definiera en planlösnings potential för kvarboende: Sovrumskapacitet. Här avses tillräcklig rumslig storlek i en vårdsituation för att bedriva vård. Det krävs en fri golvyta på 300 x 310 centimeter. Rumslig närhet mellan entré, sovrum, badrum och förvaring. Rumsorganisatoriskt innebär detta att ett av sovrummen bör ligga i anslutning till entrén, med de övriga funktioner inom sex meters gångavstånd från varandra. Funktionell autonomi. Det är en vanlig situation att en person i ett parhushåll har vårdbehov, medan den andra är frisk. Det är en stor fördel om inte hela bostaden berörs av en vårdsituation. Förbindelsen mellan entré, sovrum, badrum och förvaring bör inte gå genom lägenhetens sociala rum (kök och vardagsrum). Det är också bra om det i större lägenheter finns minst ett sovrum som inte berörs av vårdsituationen. Med de tre begreppen kan kvarboendepotentialen i en planlösning beräknas och bli en tydlig faktor i diskussionen om utformningen av framtida bostäder i Sverige.
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| 21. |
- Askling, Johan, et al.
(författare)
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Cancer risk in patients with rheumatoid arthritis treated with anti-tumor necrosis factor alpha therapies : does the risk change with the time since start of treatment?
- 2009
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Ingår i: Arthritis and Rheumatism. - : Wiley. - 0004-3591 .- 1529-0131. ; 60:11, s. 3180-3189
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE:To determine the short-term and medium-term risks of cancer in patients receiving anti-tumor necrosis factor alpha (anti-TNFalpha) therapies that have proven effective in the treatment of chronic inflammatory conditions.METHODS:By linking together data from the Swedish Biologics Register, Swedish registers of RA, and the Swedish Cancer Register, we identified and analyzed for cancer occurrence a national cohort of 6,366 patients with RA who first started anti-TNF therapy between January 1999 and July 2006. As comparators, we used a national biologics-naive RA cohort (n = 61,160), a cohort of RA patients newly starting methotrexate (n = 5,989), a cohort of RA patients newly starting disease-modifying antirheumatic drug combination therapy (n = 1,838), and the general population of Sweden. Relative risks (RRs) were estimated using Cox regression analyses, examining overall RR as well as RR by time since the first start of anti-TNF therapy, by the duration of active anti-TNF therapy, and by the anti-TNF agent received.RESULTS:During 25,693 person-years of followup in 6,366 patients newly starting anti-TNF, 240 first cancers occurred, yielding an RR of 1.00 (95% confidence interval 0.86-1.15) versus the biologics-naive RA cohort, and similar RRs versus the other 2 RA comparators. RRs did not increase with increasing time since the start of anti-TNF therapy, nor with the cumulative duration of active anti-TNF therapy. During the first year following the first treatment start, but not thereafter, dissimilar cancer risks for adalimumab, etanercept, and infliximab were observed.CONCLUSION:During the first 6 years after the start of anti-TNF therapy in routine care, no overall elevation of cancer risk and no increase with followup time were observed.
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| 24. |
- Bereczky, S., et al.
(författare)
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Spleen enlargement and genetic diversity of Plasmodium falciparum infection in two ethnic groups with different malaria susceptibility in Mali, West Africa
- 2006
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Ingår i: Transactions of the Royal Society of Tropical Medicine and Hygiene. - Amsterdam : Elsevier. - 0035-9203 .- 1878-3503. ; 100:3, s. 248-257
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Tidskriftsartikel (refereegranskat)abstract
- The high resistance to malaria in the nomadic Fulani population needs further understanding. The ability to cope with multiclonal Plasmodium falciparum infections was assessed in a cross-sectional survey in the Fulani and the Dogon, their sympatric ethnic group in Mali. The Fulani had lower parasite prevalence and densities and more prominent spleen enlargement. Spleen rates in children aged 2–9 years were 75% in the Fulani and 44% in the Dogon (P < 0.001). There was no difference in number of P. falciparum genotypes, defined by merozoite surface protein 2 polymorphism, with mean values of 2.25 and 2.11 (P = 0.503) in the Dogon and Fulani, respectively. Spleen rate increased with parasite prevalence, density and number of co-infecting clones in asymptomatic Dogon. Moreover, splenomegaly was increased in individuals with clinical malaria in the Dogon, odds ratio 3.67 (95% CI 1.65–8.15, P = 0.003), but not found in the Fulani, 1.36 (95% CI 0.53–3.48, P = 0.633). The more susceptible Dogon population thus appear to respond with pronounced spleen enlargement to asymptomatic multiclonal infections and acute disease whereas the Fulani have generally enlarged spleens already functional for protection. The results emphasize the importance of spleen function in protective immunity to the polymorphic malaria parasite.
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| 28. |
- Bjorkholm, M., et al.
(författare)
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Treatment-related risk factors for transformation to acute myeloid leukemia and myelodysplastic syndromes in myeloproliferative neoplasms
- 2011
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Ingår i: Journal of Clinical Oncology. - : American Society of Clinical Oncology: JCO. - 0732-183X .- 1527-7755. ; 29:17, s. 2410-2415
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: Patients with myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis, have a propensity to develop acute myeloid leukemia (AML) and myelodysplastic syndromes (MDSs). Using population-based data from Sweden, we assessed the role of MPN treatment and subsequent AML/MDS risk with special focus on the leukemogenic potential of hydroxyurea (HU). Methods: On the basis of a nationwide MPN cohort (N = 11,039), we conducted a nested case-control study, including 162 patients (153 and nine with subsequent AML and MDS diagnosis, respectively) and 242 matched controls. We obtained clinical and MPN treatment data for all patients. Using logistic regression, we calculated odds ratios (ORs) as measures of AML/MDS risk. Results: Forty-one (25%) of 162 patients with MPNs with AML/MDS development were never exposed to alkylating agents, radioactive phosphorous (P32), or HU. Compared with patients with who were not exposed to HU, the ORs for 1 to 499 g, 500 to 999 g, more than 1,000 g of HU were 1.5 (95% CI, 0.6 to 2.4), 1.4 (95% CI, 0.6 to 3.4), and 1.3 (95% CI, 0.5 to 3.3), respectively, for AML/MDS development (not significant). Patients with MPNs who received P32 greater than 1,000 MBq and alkylators greater than 1 g had a 4.6-fold (95% CI, 2.1 to 9.8; P = .002) and 3.4-fold (95% CI, 1.1 to 10.6; P = .015) increased risk of AML/MDS, respectively. Patients receiving two or more cytoreductive treatments had a 2.9-fold (95% CI, 1.4 to 5.9) increased risk of transformation. Conclusion: The risk of AML/MDS development after MPN diagnosis was significantly associated with high exposures of P32 and alkylators but not with HU treatment. Twenty-five percent of patients with MPNs who developed AML/MDS were not exposed to cytotoxic therapy, supporting a major role for nontreatment-related factors. © 2011 by American Society of Clinical Oncology.
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| 30. |
- Cars, T, et al.
(författare)
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Antibiotic use and bacterial complications following upper respiratory tract infections: a population-based study
- 2017
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 7:11, s. e016221-
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Tidskriftsartikel (refereegranskat)abstract
- To investigate if use of antibiotics was associated with bacterial complications following upper respiratory tract infections (URTIs).DesignEcological time-trend analysis and a prospective cohort study.SettingPrimary, outpatient specialist and inpatient care in Stockholm County, Sweden. All analyses were based on administrative healthcare data on consultations, diagnoses and dispensed antibiotics from January 2006 to January 2016.Main outcome measuresEcological time-trend analysis: 10-year trend analyses of the incidence of URTIs, bacterial infections/complications and respiratory antibiotic use.Prospective cohort study: Incidence of bacterial complications following URTIs in antibiotic-exposed and non-exposed patients.ResultsThe utilisation of respiratory tract antibiotics decreased by 22% from 2006 to 2015, but no increased trend for mastoiditis (p=0.0933), peritonsillar abscess (p=0.0544), invasive group A streptococcal disease (p=0.3991), orbital abscess (p=0.9637), extradural and subdural abscesses (p=0.4790) and pansinusitis (p=0.3971) was observed. For meningitis and acute ethmoidal sinusitis, a decrease in the numbers of infections from 2006 to 2015 was observed (p=0.0038 and p=0.0003, respectively), and for retropharyngeal and parapharyngeal abscesses, an increase was observed (p=0.0214). Bacterial complications following URTIs were uncommon in both antibiotic-exposed (less than 1.5 per 10 000 episodes) and non-exposed patients (less than 1.3 per 10 000 episodes) with the exception of peritonsillar abscess after tonsillitis (risk per 10 000 tonsillitis episodes: 32.4 and 41.1 in patients with no antibiotic treatment and patients treated with antibiotics, respectively).ConclusionsBacterial complications following URTIs are rare, and antibiotics may lack protective effect in preventing bacterial complications. Analyses of routinely collected administrative healthcare data can provide valuable information on the number of URTIs, antibiotic use and bacterial complications to patients, prescribers and policy-makers.
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| 36. |
- Helstrom, L, et al.
(författare)
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Abortion rate and contraceptive practices in immigrant and native women in Sweden
- 2003
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Ingår i: Scandinavian journal of public health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 31:6, s. 405-410
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The aim of this study was to analyse whether immigrant women request induced abortion more frequently than Swedish-born women and, if so, to study possible explanations, including contraceptive practices and attitudes. Methods: All women who requested induced abortion during a period of one year were included in the study. The 1,289 women, of whom 36% were born outside Sweden, were interviewed by a nurse-midwife who, using a structured protocol, gathered information on socioeconomic factors, reasons for abortion, experience of contraceptive methods, and family planning counselling. The proportion of women with non-Swedish origin in the study population was compared with the official demographic statistics of the corresponding area. Results: The number of women born outside Sweden who requested induced abortion was larger than expected from their proportion in the population. The immigrant women originated from 77 countries and four continents, the largest subgroup, 11%, coming from Iran. Immigrant women had less experience of contraceptive use, more previous pregnancies and more induced abortions than women born in Sweden. In a multivariate analysis, immigrant status and educational level were found to be independent risk factors for repeat abortion. Conclusion: Immigrant status seems to be an independent risk factor for induced abortion. The immigrant women originated from a wide range of cultures. There is no reason to believe that the women in this heterogeneous group should have any cultural factor in common that could explain their higher proneness to seek induced abortion. The most probable cause is that immigrant status is associated more often with low education, weak social network, poverty, unemployment, and being outside common pathways to healthcare.
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| 44. |
- Limpens, J., et al.
(författare)
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Glasshouse vs field experiments : do they yield ecologically similar results for assessing N impacts on peat mosses?
- 2012
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Ingår i: New Phytologist. - : Wiley. - 0028-646X .- 1469-8137. ; 195:2, s. 408-418
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Tidskriftsartikel (refereegranskat)abstract
- Peat bogs have accumulated more atmospheric carbon (C) than any other terrestrial ecosystem today. Most of this C is associated with peat moss (Sphagnum) litter. Atmospheric nitrogen (N) deposition can decrease Sphagnum production, compromising the C sequestration capacity of peat bogs. The mechanisms underlying the reduced production are uncertain, necessitating multifactorial experiments. We investigated whether glasshouse experiments are reliable proxies for field experiments for assessing interactions between N deposition and environment as controls on Sphagnum N concentration and production. We performed a meta-analysis over 115 glasshouse experiments and 107 field experiments. We found that glasshouse and field experiments gave similar qualitative and quantitative estimates of changes in Sphagnum N concentration in response to N application. However, glasshouse-based estimates of changes in production even qualitative assessments diverged from field experiments owing to a stronger N effect on production response in absence of vascular plants in the glasshouse, and a weaker N effect on production response in presence of vascular plants compared to field experiments. Thus, although we need glasshouse experiments to study how interacting environmental factors affect the response of Sphagnum to increased N deposition, we need field experiments to properly quantify these effects.
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| 45. |
- Liu, Fei, 1980-
(författare)
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English teaching in China : EFL teacher motivation and demotivation at the university level
- 2022
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Teacher motivation has been shown to be a major factor that affects students’ motivation to learn a second language; however, English as a foreign language (EFL) teachers’ motivation has not been given enough attention, particularly in the Chinese context where English plays a key role. Thus, this study investigates the motivation of English teachers at the university level in China in order to prepare the ground for the development of recommendations on how to enhance teacher motivation and thereby improve teaching quality and student performance. 101 in-service native Chinese EFL teachers currently working at universities in mainland China participated in the study voluntarily. A mixed methods design was adopted using a web-based questionnaire as the main instrument to explore EFL teachers’ motivation for choosing a teaching career and factors contributing to their motivation and demotivation. Individual background variables in relation to their motivation, such as their English writing proficiency, gender, teaching experience, overseas experience and types of students taught, were also examined. The questionnaire consists of closed questions adapted from previous studies and open-ended questions targeted at providing qualitative data as well as linguistic data for analyzing EFL teachers’ English writing proficiency. The results show that the EFL teachers were multi-motivated when choosing to enter the teaching profession, the main reasons being intrinsic, followed by altruistic reasons. The majority of the participants (73.30%) reported high levels of motivation at the present stage in their career. Significant differences between the first years of teaching and the present were found in the levels of teacher enthusiasm, interest and dedication. EFL teachers’ motivation was affected by various factors, among which student-related factors were reported the most important. Extrinsic factors such as a low salary and limited sources of income, unpleasant working conditions, and students’ negative attitudes were found to be demotivating factors. The results also indicated a positive correlation between EFL teachers’ level of motivation and satisfaction with self-reported English language skills (r =.435). The EFL teachers with overseas experience tended to outperform those with no overseas experience in terms of their English writing proficiency. Nevertheless, despite no statistically significant correlations between EFL teachers’ career motivation and the complexity of their written English nor between career motivation and gender, highly proficient and proficient EFL teachers tended to be predominately intrinsically motivated to enter teaching as compared with moderately proficient EFL teachers who became teachers primarily for altruistic reasons. More female (84.10%) than male EFL teachers reported becoming teachers for altruistic reasons, whereas male teachers more often reported choosing to be an EFL teacher for extrinsic reasons. Age was found to correlate negatively with the EFL teachers’ career motivation. That is, the older EFL teachers were even less likely to change their career and choose another career path than the younger ones. No significant differences in motivation were found between teachers who teach different types of students.
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| 46. |
- Ludvigsson, JF, et al.
(författare)
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Authors' reply to Makiyama and colleagues
- 2016
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Ingår i: BMJ (Clinical research ed.). - : BMJ. - 1756-1833. ; 352, s. i776-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 47. |
- Moore, Paul A., et al.
(författare)
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Assessing the peatland hummock-hollow classification framework using high-resolution elevation models : implications for appropriate complexity ecosystem modeling
- 2019
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Ingår i: Biogeosciences. - : COPERNICUS GESELLSCHAFT MBH. - 1726-4170 .- 1726-4189. ; 16:18, s. 3491-3506
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Tidskriftsartikel (refereegranskat)abstract
- The hummock-hollow classification framework used to categorize peatland ecosystem microtopography is pervasive throughout peatland experimental designs and current peatland ecosystem modeling approaches. However, identifying what constitutes a representative hummock-hollow pair within a site and characterizing hummock-hollow variability within or between peatlands remains largely unassessed. Using structure from motion (SfM), high-resolution digital elevation models (DEMs) of hummock-hollow microtopography were used to (1) examine how much area needs to be sampled to characterize site-level microtopographic variation; and (2) examine the potential role of microtopographic shape/structure on biogeochemical fluxes using plot-level data from nine northern peatlands. To capture 95% of site-level microtopographic variability, on average, an aggregate sampling area of 32 m(2) composed of 10 randomly located plots was required. Both site(i.e. transect data) and plot-level (i.e. SfM-derived DEM) results show that microtopographic variability can be described as a fractal at the submeter scale, where contributions to total variance are very small below a 0.5 m length scale. Microtopography at the plot level was often found to be non-bimodal, as assessed using a Gaussian mixture model (GMM). Our findings suggest that the non-bimodal distribution of microtopography at the plot level may result in an undersampling of intermediate topographic positions. Extended to the modeling domain, an underrepresentation of intermediate microtopographic positions is shown to lead to potentially large flux biases over a wide range of water table positions for ecosystem processes which are non-linearly related to water and energy availability at the moss surface. Moreover, our simple modeling results suggest that much of the bias can be eliminated by representing microtopography with several classes rather than the traditional two (i.e. hummock/hollow). A range of tools examined herein can be used to easily parameterize peatland models, from GMMs used as simple transfer functions to spatially explicit fractal landscapes based on simple power-law relations between microtopographic variability and scale.
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| 48. |
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| 49. |
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| 50. |
- Piatkowski, Bryan T., et al.
(författare)
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Draft Metagenome Sequences of the Sphagnum (Peat Moss) Microbiome from Ambient and Warmed Environments across Europe
- 2022
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Ingår i: Microbiology Resource Announcements. - : American Society for Microbiology. - 2576-098X. ; 11:10
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Tidskriftsartikel (refereegranskat)abstract
- We present 49 metagenome assemblies of the microbiome associated with Sphagnum (peat moss) collected from ambient, artificially warmed, and geothermally warmed conditions across Europe. These data will enable further research regarding the impact of climate change on plant-microbe symbiosis, ecology, and ecosystem functioning of northern peatland ecosystems.
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