| 1. |
- Pettersson, Stefan, 1972, et al.
(author)
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Off- to in-season body composition adaptations in elite male and female endurance and power event athletics competitors: an observational study
- 2024
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In: BMC Sports Science, Medicine and Rehabilitation. - : Springer Nature. - 2052-1847. ; 16
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Journal article (peer-reviewed)abstract
- Background: Monitoring elite athletes’ body composition (BC) is vital for health and optimizing performance in sports emphasizing leanness, such as athletics. This study aims to investigate and compare sex- and event-specific off-to in-season BC changes in endurance and power event athletics competitors.Methods: Elite male and female endurance athletes (> 800 m runners; n = 21) and power event athletes (sprinters, jumpers; n = 32) underwent dual-energy X-ray absorptiometry (DXA) scans for whole and regional lean mass (LM), fat mass (FM), bone mineral content (BMC), and density (BMD) during off-season (September-October) and in-season (April-May). Linear mixed models tested between-group off-season differences in BC, within-group off-season to in-season changes, and between-group differences in change. To assess meaningful or least significant changes (LSC) in BC, DXA precision errors were determined from two consecutive total body scans in a subsample of athletes (n = 30).Results: Male athletes (n = 26) gained significantly (p < 0.05) more body mass (BM; mean difference 1.5 [95% confidence interval (CI):0.5–2.4] kg), LM (843 [95% CI:-253:1459] g), and trunk LM (756 [-502:1156] g) than female athletes (n = 27). The proportion of changes in athlete’s BC exceeding the LSC threshold for LM and trunk LM were 70% and 65% in males, and 48% and 26% in females. Significant (p < 0.05) within-group off-season to in-season increases in LM were found for male endurance and power athletes, and female power athletes. All groups significantly increased BMD (p < 0.05). Only male and female power athletes had significant in- to-off-season increases in BMC. 80% of all athletes who had a meaningful increase in BMC belonged to the power event group. No significant within- or between group change in FM was observed.Conclusions: The present study found that male athletes gained more BM, LM and trunk LM than females. Within-group increases in regional and whole-body LM and BMC were predominantly found among power event competitors. Incorporating individual meaningful changes alongside traditional statistics provided additional insights into sex and event-group differences. Future research on elite athletic event groups should include DXA measurements closer to major outdoor-season competitions, coupled with site-specific measures (ultrasound, MRI) for better detection of subtle changes in LM and FM.
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| 2. |
- Arndt, Anton, 1968-, et al.
(author)
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Editorial
- 2021
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In: Footwear Science. - : Taylor & Francis. - 1942-4280 .- 1942-4299. ; 13:SUP1, s. S1-S3
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Journal article (other academic/artistic)
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| 3. |
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| 4. |
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| 5. |
- Barisch-Fritz, B., et al.
(author)
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Evaluation of the rule-of-thumb: calculation of the toe allowance for developing feet
- 2016
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In: Footwear Science. - : Informa UK Limited. - 1942-4280 .- 1942-4299. ; 8:3, s. 119-127
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Journal article (peer-reviewed)abstract
- The amount of toe allowance (TA, the space in front of the toes) in children's shoes is physiologically important and often estimated by the rule-of-the-parent's-thumb. Besides this, other rules-of-thumb exist mainly based on experiences or footprint analysis. The aim of this study is to scientifically evaluate these rules-of-thumb. TA was calculated as a function of growth rate, foot extension, and walking advance based on three-dimensional (3D) foot scans of 2554 children (6-16 years) during standing and walking. Foot extension was determined as the difference in foot length between static and dynamic weight-bearing, walking advance as movement of the most anterior point of toes, and growth rate as semi-annual foot growth. TA was smaller than all rules-of-thumb and was influenced by gender and foot length. These findings primarily present TA based on 3D foot scans which is important for shoe construction. It is recommended to use 90th percentiles instead of mean values for the construction of TA.
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| 6. |
- Barisch-Fritz, B., et al.
(author)
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Foot deformation during walking: differences between static and dynamic 3D foot morphology in developing feet
- 2014
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In: Ergonomics. - : Informa UK Limited. - 0014-0139 .- 1366-5847. ; 57:6, s. 921-933
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Journal article (peer-reviewed)abstract
- The complex functions of feet require a specific composition, which is progressively achieved by developmental processes. This development should take place without being affected by footwear. The aim of this study is to evaluate differences between static and dynamic foot morphology in developing feet. Feet of 2554 participants (6-16 years) were recorded using a new scanner system (DynaScan4D). Each foot was recorded in static half and full weight-bearing and during walking. Several foot measures corresponding to those used in last construction were calculated. The differences were identified by one-way ANOVA and paired Student's t-test. Static and dynamic values of each foot measure must be considered to improve the fit of footwear. In particular, footwear must account for the increase of forefoot width and the decrease of midfoot girth. Furthermore, the toe box should have a more rounded shape. The findings are important for the construction of footwear for developing feet. Practitioner Summary: Until now, foot deformation has not been analysed in developing feet. The presented differences between standing and walking of 2554 children were obtained using a new dynamic 3D scanner system. The results show that especially differences between foot width and girth measures and angles must be considered in footwear construction.
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| 7. |
- Björkman, Anne, 1981, et al.
(author)
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Plant functional trait change across a warming tundra biome
- 2018
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In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 562:7725, s. 57-62
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Journal article (peer-reviewed)abstract
- The tundra is warming more rapidly than any other biome on Earth, and the potential ramifications are far-reaching because of global feedback effects between vegetation and climate. A better understanding of how environmental factors shape plant structure and function is crucial for predicting the consequences of environmental change for ecosystem functioning. Here we explore the biome-wide relationships between temperature, moisture and seven key plant functional traits both across space and over three decades of warming at 117 tundra locations. Spatial temperature–trait relationships were generally strong but soil moisture had a marked influence on the strength and direction of these relationships, highlighting the potentially important influence of changes in water availability on future trait shifts in tundra plant communities. Community height increased with warming across all sites over the past three decades, but other traits lagged far behind predicted rates of change. Our findings highlight the challenge of using space-for-time substitution to predict the functional consequences of future warming and suggest that functions that are tied closely to plant height will experience the most rapid change. They also reveal the strength with which environmental factors shape biotic communities at the coldest extremes of the planet and will help to improve projections of functional changes in tundra ecosystems with climate warming.
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| 8. |
- Björkman, Anne, 1981, et al.
(author)
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Tundra Trait Team: A database of plant traits spanning the tundra biome
- 2018
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In: Global Ecology and Biogeography. - : Wiley. - 1466-822X .- 1466-8238. ; 27:12, s. 1402-1411
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Journal article (peer-reviewed)abstract
- © 2018 The Authors Global Ecology and Biogeography Published by John Wiley & Sons Ltd Motivation: The Tundra Trait Team (TTT) database includes field-based measurements of key traits related to plant form and function at multiple sites across the tundra biome. This dataset can be used to address theoretical questions about plant strategy and trade-offs, trait–environment relationships and environmental filtering, and trait variation across spatial scales, to validate satellite data, and to inform Earth system model parameters. Main types of variable contained: The database contains 91,970 measurements of 18 plant traits. The most frequently measured traits (>1,000 observations each) include plant height, leaf area, specific leaf area, leaf fresh and dry mass, leaf dry matter content, leaf nitrogen, carbon and phosphorus content, leaf C:N and N:P, seed mass, and stem specific density. Spatial location and grain: Measurements were collected in tundra habitats in both the Northern and Southern Hemispheres, including Arctic sites in Alaska, Canada, Greenland, Fennoscandia and Siberia, alpine sites in the European Alps, Colorado Rockies, Caucasus, Ural Mountains, Pyrenees, Australian Alps, and Central Otago Mountains (New Zealand), and sub-Antarctic Marion Island. More than 99% of observations are georeferenced. Time period and grain: All data were collected between 1964 and 2018. A small number of sites have repeated trait measurements at two or more time periods. Major taxa and level of measurement: Trait measurements were made on 978 terrestrial vascular plant species growing in tundra habitats. Most observations are on individuals (86%), while the remainder represent plot or site means or maximums per species. Software format: csv file and GitHub repository with data cleaning scripts in R; contribution to TRY plant trait database (www.try-db.org) to be included in the next version release.
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| 9. |
- Boije af Gennäs, Klara, et al.
(author)
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Researching overuse injuries among adolescent soccer players using an interdisciplinary approach
- 2018
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In: Svensk Beteendevetenskaplig Idrottsforsknings konferens (SVEBI).
-
Conference paper (other academic/artistic)abstract
- Introduction Adolescent soccer players frequently suffer traumatic and overuse injuries. Research shows that injuries at a young age are problematic as they may limit continued participation and are a risk factor for future injuries (Junge, Cheung, Edwards, & Dvorak, 2004). Current findings indicate that injuries are caused by a multitude of factors, however, this knowledge is not integrated and does not provide a contextualized picture of how an injury develops. With a contextualized picture there can be a gain in information on social and temporal development of an injury. And detailed understanding of how an injury develops. Aim and theoretical framework The purpose of this poster is to provide an overview of the methodology used in an interdisciplinary research project on the development of overuse injuries among adolescent soccer players. In order to achieve this, the aim is to use Bronfenbrenner’s (2005) bioecological theory to create a contextualized view of factors that can create injuries. Method The project follows case-study inquiry. This inquiry has two main data production items. The first item contains a questionnaire, which all participants complete on a weekly basis for 6 months. The questionnaire is based on Clarsen’s (2013) Oslo Sports Trauma research on health problems (OSTRC) and provides a base and longitudinal overview of health problems. The second item contains five data gathering methods and is conducted as a case portfolio consisting of: a) biomechanical profiling based on a 3D running motion capture; b) isometric strength measurements and clinical flexibility tests; c) a training protocol filled in by the soccer players coach; d) observations during soccer practice; and e) semistructured interviews with the soccer players and their coaches. The sample selection is information-oriented, which means that samples are selected based on their expected content information (Flyvbjerg, 2006). Data is analysed for each employed method, as well as through an integrated portfolio analysis inspired by Bronfenbrenner s (2005) ́ bioecological theory. Results The cases’ injury history, individual biomedical, training, contextual and subjectivity results demonstrate individual factors that resulted in an injury. In relating these to each other, the two cases demonstrate how an injury develops over time, in particular contexts, in relation to particular training methods and coaching strategies, and as a result of individual dispositions and assumptions. Discussion and conclusions The findings of the study allow the collation of injury history, individual biomedical, training, contextual and subjectivity factors in a bioecological model of injury development. This model has the potential to create more effective injury prevention guidelines. The case-study approach provides concrete and contextdependent knowledge (Flyvbjerg, 2006), to develop case-oriented expertise, expanding the knowledge on the interdisciplinary interaction of overuse injury development. References Bronfenbrenner, U. (2005). Making human beings human: Bioecological perspectives on human development. Thousand Oaks: Sage Publications. Clarsen. B., Myklebust, G., & Bahr, R. (2013). Development and validation of a new method for the registration of overuse injuries in sports injury epidemiology: The Oslo Sports Trauma Research Centre (OSTRC) overuse injury questionnaire. British Journal of Sports Medicine, 47(8), 495-502. Flyvbjerg, B. (2006). Five Misunderstandings About Case-Study Research. Qualitative Inquiry, 12(2), 219-245. Junge, A., Cheung, K., Edwards, T., & Dvorak, J. (2004). Injuries in youth amateur soccer and rugby players—comparison of incidence and characteristics. British Journal of Sports Medicine, 38(2), 168-172. doi:10.1136/bjsm.2002.003020
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| 10. |
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| 11. |
- Casalbuoni, Sara, et al.
(author)
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COLDDIAG: A Cold Vacuum Chamber for Diagnostics
- 2011
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In: IEEE Transactions on Applied Superconductivity. - 1051-8223. ; 21:3, s. 2300-2303
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Journal article (peer-reviewed)abstract
- One of the still open issues for the development of superconducting insertion devices is the understanding of the heat load induced by the beam passage. With the aim of measuring the beam heat load to a cold bore and in order to gain a deeper understanding in the beam heat load mechanisms, a cold vacuum chamber for diagnostics is under construction. We plan to have access with the same set-up to a number of different diagnostics, so we are implementing: i) retarding field analysers to measure the electron flux, ii) temperature sensors to measure the total heat load, iii) pressure gauges, iv) and mass spectrometers to measure the gas content. The inner vacuum chamber will be removable in order to test different geometries and materials. COLDDIAG is built to fit in a short straight section at ANKA, but we are proposing its installation in different synchrotron light sources with different energies and beam characteristics. A first installation in DIAMOND is planned in June 2011. Here we describe the technical design report of this device and the planned measurements with beam.
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| 12. |
- Debette, Stéphanie, et al.
(author)
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Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection
- 2015
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 47, s. 78-83
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Journal article (peer-reviewed)abstract
- Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a major cause of ischemic stroke in young adults although relatively uncommon in the general population (incidence of 2.6/100,000 per year)1. Minor cervical traumas, infection, migraine and hypertension are putative risk factors1–3, and inverse associations with obesity and hypercholesterolemia are described3,4. No confirmed genetic susceptibility factors have been identified using candidate gene approaches5. We performed genome-wide association studies (GWAS) in 1 1,393 CeAD cases and 1 14,416 controls. The rs9349379[G] allele (PHACTR1) was associated with lower CeAD risk (odds ratio (OR) = 0.75, 95% confidence interval (CI) = 0.69–0.82; P = 4.46 × 1 10−10), with confirmation in independent follow-up samples (659 CeAD cases and 2,648 controls; P = 3.91 1 × 1 10−3; combined P = 1 1.00 × 1 10−1111). The rs9349379[G] allele was previously shown to be associated with lower risk of migraine and increased risk of myocardial infarction6–9. Deciphering the mechanisms underlying this pleiotropy might provide important information on the biological underpinnings of these disabling conditions.
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| 13. |
- Desai, Pia, et al.
(author)
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Effectiveness of an 18-week general strength and foam-rolling intervention on running-related injuries in recreational runners
- 2023
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In: Scandinavian Journal of Medicine & Science in Sports. - : Wiley. - 0905-7188 .- 1600-0838. ; 33:5, s. 766-775
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Journal article (peer-reviewed)abstract
- Rationale: More research is needed to uncover the effectiveness of combined strength and foam-rolling interventions to prevent running-related injuries. Objectives: To evaluate effectiveness of an 18-week general strength and foam-rolling intervention on the incidence of running-related injuries. Method: This is an 18-week observational comparative study. A total of 433 recreational runners participated (n = 203 female). The intervention group (n = 228) performed general strength and foam-rolling exercises twice weekly for 18 weeks, the control group (n = 205) maintained their regular training habits. Running volume and running-related pain were reported weekly. Secondary analyses were performed on the subgroups of the intervention group based on compliance; low compliance (n = 100), intermediate compliance (n = 63), and high compliance (n = 65). Cumulative incidence proportions were calculated and time-to- event statistics were performed to compare survival times between groups. Univariate cox proportional hazards ratio was calculated to estimate the risk of running-related injuries at 18 weeks. Results: A total of 100 running-related injuries were sustained. The cumulative incidence proportion for the control and intervention groups was 27.1% (95% CI:21.4–33.9) and 23.0% (95% CI: 17.8–29.4), respectively. No statistically significant difference was found between the overall intervention group and control group (log- rank p = 0.31). A significant difference existed between the high-compliance subgroup and the control group (log-rank p = 0.00). Highly compliant runners were 85% less likely (hazard rate ratio = 0.15; 95% CI: 0.05–0.46) to sustain an injury during the study compared with controls. Conclusion: Recreational runners highly compliant with the intervention were 85% less likely and took on average 57 days longer to sustain a running-related injury when compared with controls, with a cumulative incidence proportion of 4.6% after 18 weeks.
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| 14. |
- Desai, Pia, et al.
(author)
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Recreational Runners With a History of Injury Are Twice as Likely to Sustain a Running-Related Injury as Runners With No History of Injury: A 1-Year Prospective Cohort Study
- 2021
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In: Journal of Orthopaedic and Sports Physical Therapy. - 0190-6011. ; 51:3, s. 144-150
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Journal article (peer-reviewed)abstract
- To investigate (1) the cumulative incidence proportion and the most common anatomical locations of running-related injuries in recreational runners, and (2) the associations between running-related injuries and previous injury, running experience, weekly running distance, age, gender and body mass index (BMI).A one-year prospective cohort study.224 recreational runners (average of 15km weekly running distance for the past 12 months) were included (89 women, 135 men). Pain information was reported weekly for one year and all running-related injuries with time-loss or requiring medical consultation were recorded. We accounted for censoring when calculating cumulative incidence proportion, and used crude Cox proportional hazards regression to evaluate if the variables of interest were associated with running-related injuries.The one-year cumulative incidence proportion of running-related injuries was 46% (95% CI: 38.4-54.1). The most common anatomical locations were the knee (20 of 75, 27%) and Achilles tendon/calf (19 of 75, 25%). Previous injury was associated with a higher injury rate (hazard ratio: 1.9, 95% CI: 1.2-3.2), while the other variables had no statistically significant association with injury.There were 75 running-related injuries during the one-year surveillance period for a cumulative incidence proportion of 46%. The most common injuries were to the knee and Achilles tendon/calf. Recreational runners with a previous injury were twice as likely to sustain a running-related injury than runners with no previous injury.
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| 15. |
- Fridolfsson, Jonatan, 1992, et al.
(author)
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Measurement of physical activity by shoe-based accelerometers—calibration and free-living validation
- 2021
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In: Sensors. - : MDPI AG. - 1424-8220. ; 21:7
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Journal article (peer-reviewed)abstract
- There is conflicting evidence regarding the health implications of high occupational physical activity (PA). Shoe-based accelerometers could provide a feasible solution for PA measurement in workplace settings. This study aimed to develop calibration models for estimation of energy expenditure (EE) from shoe-based accelerometers, validate the performance in a workplace setting and compare it to the most commonly used accelerometer positions. Models for EE estimation were calibrated in a laboratory setting for the shoe, hip, thigh and wrist worn accelerometers. These models were validated in a free-living workplace setting. Furthermore, additional models were devel-oped from free-living data. All sensor positions performed well in the laboratory setting. When the calibration models derived from laboratory data were validated in free living, the shoe, hip and thigh sensors displayed higher correlation, but lower agreement, with measured EE compared to the wrist sensor. Using free-living data for calibration improved the agreement of the shoe, hip and thigh sensors. This study suggests that the performance of a shoe-based accelerometer is similar to the most commonly used sensor positions with regard to PA measurement. Furthermore, it high-lights limitations in using the relationship between accelerometer output and EE from a laboratory setting to estimate EE in a free-living setting.
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| 16. |
- Fridolfsson, Jonatan, 1992, et al.
(author)
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Workplace activity classification from shoebased movement sensors
- 2020
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In: BMC Biomedical Engineering. - : Springer Science and Business Media LLC. - 2524-4426. ; 2
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Journal article (peer-reviewed)abstract
- Background: High occupational physical activity is associated with lower health. Shoe-based movement sensors can provide an objective measurement of occupational physical activity in a lab setting but the performance of such methods in a free-living environment have not been investigated. The aim of the current study was to investigate the feasibility and accuracy of shoe sensor-based activity classification in an industrial work setting. Results: An initial calibration part was performed with 35 subjects who performed different workplace activities in a structured lab setting while the movement was measured by a shoe-sensor. Three different machine-learning models (random forest (RF), support vector machine and k-nearest neighbour) were trained to classify activities using the collected lab data. In a second validation part, 29 industry workers were followed at work while an observer noted their activities and the movement was captured with a shoe-based movement sensor. The performance of the trained classification models were validated using the free-living workplace data. The RF classifier consistently outperformed the other models with a substantial difference in in the free-living validation. The accuracy of the initial RF classifier was 83% in the lab setting and 43% in the free-living validation. After combining activities that was difficult to discriminate the accuracy increased to 96 and 71% in the lab and freeliving setting respectively. In the free-living part, 99% of the collected samples either consisted of stationary activities or walking. Conclusions: Walking and stationary activities can be classified with high accuracy from a shoe-based movement sensor in a free-living occupational setting. The distribution of activities at the workplace should be considered when validating activity classification models in a free-living setting.
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| 17. |
- Gemmell, Neil J., et al.
(author)
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The tuatara genome reveals ancient features of amniote evolution
- 2020
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In: Nature. - : Springer Nature. - 0028-0836 .- 1476-4687. ; 584:7821, s. 403-409
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Journal article (peer-reviewed)abstract
- The tuatara (Sphenodon punctatus)—the only living member of the reptilian order Rhynchocephalia (Sphenodontia), once widespread across Gondwana1,2—is an iconic species that is endemic to New Zealand2,3. A key link to the now-extinct stem reptiles (from which dinosaurs, modern reptiles, birds and mammals evolved), the tuatara provides key insights into the ancestral amniotes2,4. Here we analyse the genome of the tuatara, which—at approximately 5 Gb—is among the largest of the vertebrate genomes yet assembled. Our analyses of this genome, along with comparisons with other vertebrate genomes, reinforce the uniqueness of the tuatara. Phylogenetic analyses indicate that the tuatara lineage diverged from that of snakes and lizards around 250 million years ago. This lineage also shows moderate rates of molecular evolution, with instances of punctuated evolution. Our genome sequence analysis identifies expansions of proteins, non-protein-coding RNA families and repeat elements, the latter of which show an amalgam of reptilian and mammalian features. The sequencing of the tuatara genome provides a valuable resource for deep comparative analyses of tetrapods, as well as for tuatara biology and conservation. Our study also provides important insights into both the technical challenges and the cultural obligations that are associated with genome sequencing.
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| 18. |
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| 19. |
- Grau, Stefan, et al.
(author)
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Improvement of safety shoe fit - evaluation of dynamic foot structure
- 2018
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In: Footwear Science. - : Informa UK Limited. - 1942-4280 .- 1942-4299. ; 10:3, s. 179-187
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Journal article (peer-reviewed)abstract
- Safety shoe development is based on static foot measures, which are transferred to last design. However, workplaces are not just static (‘standing workplaces only’). The aim of the present study is to examine static and dynamic foot loading of workers to determine whether foot morphology changes between different loading situations. The results could be used to improve last and shoe design to improve the fit of safety shoes. 1024 workers at different industrial locations in Germany took part in the study. The DynaScan4D dynamic scanner system was used to measure static and dynamic foot morphology during different phases of ground contact. All scan variables were selected based on measures required in the last development process. Cohen’s d (effect size) was calculated to identify individual differences between maximum values during the stance phase of walking and static values in standing. Stepwise multiple linear regression analysis was performed to identify possible influencing variables with regard to differences between static and dynamic values. Several foot measures showed relevant differences between dynamic and static loading. Interestingly, most length, width, height, and angular measures increased during dynamic loading (compared to static loading), whereas all circumference measures decreased. None of the tested variables (age, BMI, gender) predicted the differences between the two loading situations. Most dynamic changes are practical relevant changes between static and dynamic loading. Regarding the fit of safety shoes, it seems appropriate to adapt these changes to the last or shoe design.
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| 20. |
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| 21. |
- Hall, Ulrika Andersson, et al.
(author)
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Exercise, aerobic fitness, and muscle strength in relation to glucose tolerance 6 to 10 years after gestational diabetes
- 2022
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In: Diabetes Research and Clinical Practice. - : Elsevier BV. - 0168-8227. ; 191
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Journal article (peer-reviewed)abstract
- Aims: We sought to identify self-reported exercise and objectively measured fitness variables associated with glucose tolerance and metabolic health 6–10 years after gestational diabetes (GDM) Methods: Women (n = 84) underwent oral glucose tolerance testing (OGTT), body composition measurements, and lifestyle questionnaires 6 and 10 years after GDM. In a subset (n = 45), peak oxygen uptake (VO2peak), peak fat oxidation, and maximal isometric strength of five muscle groups were tested. Results: At 10 years, 41 women (49%) had impaired glucose metabolism or type 2 diabetes (T2D). VO2peak and muscle strength were lowest in the T2D group. In a regression analysis, VO2peak and all strength measurements were associated negatively with HbA1c and waist-hip ratio and positively with high-density lipoprotein cholesterol. However, only muscle strength was associated with fasting and area-under-the-curve glucose. For changes between the 6- and 10-year follow-ups, only muscle strength was associated with HbA1c change, whereas both VO2peak and strength were associated with high-density lipoprotein level and changes in waist-hip ratio. Peak fat oxidation and self-reported physical activity showed no or weak relationships with glycemic variables. Conclusion: Objectively measured fitness variables, particularly muscle strength, were strongly associated with glycemic and other metabolic outcomes in a high-risk group after GDM.
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| 22. |
- Hausken, Solveig E. S., 1986, et al.
(author)
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Injury-free children and adolescents : Towards better practice in Swedish football (FIT project)
- 2018
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In: Research Ideas and Outcomes. - : Pensoft Publishers. - 2367-7163. ; 4, s. 1-16
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Journal article (peer-reviewed)abstract
- This interdisciplinary research project will produce evidence-based recommendations on how injuries in Swedish youth football (soccer) can be prevented. Fewer injuries will positively impact athlete health, performance and career longevity and have the potential to promote life-long physical activity and wellbeing. Injury pattern research demonstrates that injuries are a significant problem in (Swedish) youth sport. Football has a higher traumatic and overuse injury rate than many contact/ collision sports (e.g., field hockey, basketball). In research on youth football, the incidence of overuse training injuries was measured as high as 15.4 injuries per 1000 training hours, and the incidence of traumatic and overuse match injuries was 47.5 injuries per 1000 match hours. The injury frequency is alarming and applies to the 54% of children aged 7-14 and the 39% of youths aged 15-19 years who participate in Swedish organised sports. A large body of research identifies injury risk factors and preventative strategies; however, as the recent IOC consensus statement on youth athletic development points out, the existing, mostly bio-medical knowledge does not provide effective evidence-based injury prevention strategies. To address this deficit, interdisciplinary and context-driven knowledge on injury development in youth sport is needed.The proposed project will produce scientific evidence through four consecutive studies: a) Questionnaire to register the types, frequency and management of injuries; b) Laboratory testing of biomechanical, clinical and training-specific parameters to establish individual physical and sport-specific dispositions; c) Observation of sporting contexts to understand sporting cultures, coaching methods and coach-athlete relationships; and d) Interviews with coaches and players to recognize knowledge that shapes coaching and training. The sample of youth players will be recruited from Sweden’s most popular and injury-prone sport: football. Each of the four studies will conduct its own data production and analyses, and a collective analysis will produce integrated evidence. Concrete recommendations for best sporting practice will be developed, which will serve sporting federations, sport education institutions, coaches, sport support staff and players.
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| 23. |
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| 24. |
- Hausken-Sutter, Solveig E., et al.
(author)
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Interdisciplinary sport injury research and the integration of qualitative and quantitative data.
- 2023
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In: BMC Medical Research Methodology. - : BioMed Central (BMC). - 1471-2288. ; 23:1
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Journal article (peer-reviewed)abstract
- BACKGROUND: To understand and prevent sport injuries, scholars have employed different scientific approaches and research methods. Traditionally, this research has been monodisciplinary, relying on one subdiscipline of sport science and applying qualitative or quantitative research methods. Recently, scholars have argued that traditional approaches fail to address contextual components of sport and the nonlinear interactions between different aspects in and around the athlete, and, as a way forward, called for alternative approaches to sport injury research. Discussion of alternative approaches are today taking place, however, practical examples that demonstrate what such approaches entails are rare. Therefore, the purpose of this paper is to draw on an interdisciplinary research approach to (1) outline an interdisciplinary case analysis procedure (ICAP); and (2) provide an example for future interdisciplinary sport injury research.METHODS: We adopt an established definition and application of interdisciplinary research to develop and pilot the ICAP for interdisciplinary sport injury teams aiming to integrate qualitative and quantitative sport injury data. The development and piloting of ICAP was possible by drawing on work conducted in the interdisciplinary research project "Injury-free children and adolescents: Towards better practice in Swedish football" (the FIT project).RESULTS: The ICAP guides interdisciplinary sport injury teams through three stages: 1. Create a more comprehensive understanding of sport injury aetiology by drawing on existing knowledge from multiple scientific perspectives; 2. Collate analysed qualitative and quantitative sport injury data into a multilevel data catalogue; and 3. Engage in an integrated discussion of the collated data in the interdisciplinary research team.CONCLUSION: The ICAP is a practical example of how an interdisciplinary team of sport injury scholars can approach the complex problem of sport injury aetiology and work to integrate qualitative and quantitative data through three stages. The ICAP is a step towards overcoming the obstacles of integrating qualitative and quantitative methods and data that scholars have identified.
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| 25. |
- Hausken-Sutter, Solveig E., et al.
(author)
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Methodological implications of adapting and applying a web‑based questionnaire on health problems to adolescent football players
- 2021
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In: BMC Medical Research Methodology. - : BioMed Central. - 1471-2288. ; 21:252
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Journal article (peer-reviewed)abstract
- Background: The Oslo Sport Trauma Research Centre Questionnaire on Health Problems (OSTRC‑H) has become a popular tool to monitor health status in athletes. Originally developed for adult athletes, the tool is today also being used in adolescent athletes. However, little is known on the suitability of the questionnaire for the adolescent age group and the methodological implications of applying the tool to prospectively monitor illness and injury. To address this gap in methodological knowledge, the aim of this study is to outline and discuss the adaption and application process of the OSTRC‑H to adolescent football players.Method: The adaption process included a slightly modified back‑translation method to translate the questionnaire. The application process included a web‑based version of the Swedish OSTRC‑H sent out once a week over 23 weeks to 115 adolescent football players aged 10‑19 attending two football schools in Sweden. The response rate and prevalence of health problems over 23 weeks were calculated as feasibility indicators. Additionally, comprehensibility questions were added to the questionnaire in the end of the study.Result: No major disagreement was found between the original and translated versions of the questionnaire. However, significant changes to the wording of the questions and answer categories were necessary to adapt it to ado‑lescents. A visual body figure was also added. The average weekly response rate was 38% (SD 13.5). To increase this rate, questionnaire data was gathered retrospectively through telephone and email contact with the participants and their parents, elevating the response rate to 53% (SD 15.5). The adolescents experienced the questionnaire as easy to understand and to cover all relevant health problems.Conclusion: Our study demonstrates the importance of adapting the questionnaire to the adolescent target group through translation, pre‑tests, adjustments of wording and the facilitation of answering the questionnaire using a visual body figure. The study further shows the importance of keeping close and personal contact with the participants, their parents, teachers, and coaches throughout data collection. Future studies should take into account the age group and study context when adapting and applying the OSTRC‑H to adolescents.
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| 26. |
- Hausken-Sutter, Solveig E., et al.
(author)
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Youth sport injury research : a narrative review and the potential of interdisciplinarity
- 2021
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In: BMJ Open Sport & Exercise Medicine. - : BMJ Publishing Group Ltd. - 2055-7647. ; 7:1
-
Research review (peer-reviewed)abstract
- To prevent sports injuries, researchers have aimed to understand injury aetiology from both the natural and social sciences and through applying different methodologies. This research has produced strong disciplinary knowledge and a number of injury prevention programmes. Yet, the injury rate continues to be high, especially in youth sport and youth football. A key reason for the continued high injury rate is the development of injury prevention programmes based on monodisciplinary knowledge that does not account for the complex nature of sport injury aetiology. The purpose of this paper is to consider and outline an interdisciplinary research process to research the complex nature of sport injury aetiology. To support our proposition, we first present a narrative review of existing youth football and youth sport injury research demonstrating an absence of paradigmatic integration across the research areas’ main disciplines of biomedicine, psychology and sociology. We then demonstrate how interdisciplinary research can address the complexity of youth sport injury aetiology. Finally, we introduce the interdisciplinary process we have recently followed in a youth football injury research project. While further research is necessary, particularly regarding the integration of qualitative and quantitative sport injury data, we propose that the pragmatic interdisciplinary research process can be useful for researchers who aim to work across disciplines and paradigms and aim to employ methodological pluralism in their research.
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| 27. |
- Hecker, Andreas, et al.
(author)
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Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1 beta Release
- 2015
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In: Journal of Immunology. - : AMER ASSOC IMMUNOLOGISTS. - 0022-1767 .- 1550-6606. ; 195:5, s. 2325-2334
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Journal article (peer-reviewed)abstract
- IL-1 beta is a potent proinflammatory cytokine of the innate immune system that is involved in host defense against infection. However, increased production of IL-1 beta plays a pathogenic role in various inflammatory diseases, such as rheumatoid arthritis, gout, sepsis, stroke, and transplant rejection. To prevent detrimental collateral damage, IL-1 beta release is tightly controlled and typically requires two consecutive danger signals. LPS from Gram-negative bacteria is a prototypical first signal inducing pro-IL-1 beta synthesis, whereas extracellular ATP is a typical second signal sensed by the ATP receptor P2X7 that triggers activation of the NLRP3-containing inflammasome, proteolytic cleavage of pro-IL-1 beta by caspase-1, and release of mature IL-1 beta. Mechanisms controlling IL-1 beta release, even in the presence of both danger signals, are needed to protect from collateral damage and are of therapeutic interest. In this article, we show that acetylcholine, choline, phosphocholine, phosphocholine-modified LPS from Haemophilus influenzae, and phosphocholine-modified protein efficiently inhibit ATP-mediated IL-1 beta release in human and rat monocytes via nicotinic acetylcholine receptors containing subunits alpha 7, alpha 9, and/or alpha 10. Of note, we identify receptors for phosphocholine-modified macromolecules that are synthesized by microbes and eukaryotic parasites and are well-known modulators of the immune system. Our data suggest that an endogenous anti-inflammatory cholinergic control mechanism effectively controls ATP-mediated release of IL-1 beta and that the same mechanism is used by symbionts and misused by parasites to evade innate immune responses of the host.
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| 28. |
- Hein, Tobias, 1982, et al.
(author)
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Can minimal running shoes imitate barefoot heel-toe running patterns? A comparison of lower leg kinematics
- 2014
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In: Journal of Sport and Health Science. - : Elsevier BV. - 2095-2546. ; 3:2, s. 67-73
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Journal article (peer-reviewed)abstract
- Background: Numerous studies about the interaction between footwear (and barefoot) and kinematic and kinetic outcomes have been published over the last few years. Recent studies however lead to the conclusion that the assumed interactions depend mainly on the subjects' experience of barefoot (BF) walking/running, the preferred running strike pattern, the speed, the hardness of the surface, the thickness of the midsole material, and the runners' level of ability. The aim of the present study was to investigate lower leg kinematics of BF running and running in minimal running shoes (MRS) to assess comparability of BF kinematics in both conditions. To systematically compare both conditions we monitored the influencing variables described above in our measurement setup. We hypothesized that running in MRS does not alter lower leg kinematics compared to BF running. Methods: Thirty-seven subjects, injury-free and active in sports, ran BF on an EVA foam runway, and also ran shod wearing Nike Free 3.0 on a tartan indoor track. Lower-leg 3D kinematics was measured to quantify rearfoot and ankle movements. Skin markers were used in both shod and BF running. Results: All runners revealed rearfoot strike pattern when running barefoot. Differences between BF and MRS running occurred particularly during the initial stance phase of running, both in the sagittal and the frontal planes. BF running revealed a flatter foot placement, a more plantar flexed ankle joint and less inverted rearfoot at touchdown compared to MRS running. Conclusion: BF running does not change the landing automatically to forefoot running, especially after a systematic exclusion of surface and other influencing factors. The Nike Free 3.0 mimics some BF features. Nevertheless, changes in design of the Nike Free should be considered in order to mimic BF movement even more closely. Copyright (C) 2014, Shanghai University of Sport. Production and hosting by Elsevier B. V. All rights reserved.
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| 29. |
- Hein, Tobias, 1982, et al.
(author)
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Prospective analysis of intrinsic and extrinsic risk factors on the development of Achilles tendon pain in runners
- 2014
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In: Scandinavian Journal of Medicine & Science in Sports. - : Wiley. - 0905-7188 .- 1600-0838. ; 24:3
-
Journal article (peer-reviewed)abstract
- There are currently no generally accepted, consistent results that clearly characterize factors causing Achilles tendon pain (AT) in runners. Therefore, we carried out a prospective study to evaluate the multifactorial influence of clinical, biomechanical (isometric strength measurements and three-dimensional kinematics) and training-related risk factors on the development of AT. Two hundred sixty-nine uninjured runners were recruited and underwent an initial examination. One hundred forty-two subjects completed their participation by submitting training information on a weekly basis over a maximal period of 1 year. Forty-five subjects developed an overuse injury, with 10 runners suffering from AT. In an uninjured state, AT runners already demonstrated decreased knee flexor strength and abnormal lower leg kinematics (sagittal knee and ankle joint) compared with a matched control group. A relationship between years of running experience or previous overuse injuries and the development of new symptoms could not be established. The interrelationship of biomechanical and training-specific variables on the generation of AT is evident. A combination of alterations in lower leg kinematics and higher impacts caused by fast training sessions might lead to excessive stress on the Achilles tendon during weight bearing and thus to AT in recreational runners.
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| 30. |
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| 31. |
- Herfurth, M., et al.
(author)
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Gait velocity and step length at baseline predict outcome of Nordic walking training in patients with Parkinson's disease
- 2015
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In: Parkinsonism & Related Disorders. - : Elsevier BV. - 1353-8020. ; 21:4, s. 413-416
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Journal article (peer-reviewed)abstract
- Background: The impact of Nordic walking (NW) in Parkinson's disease (PD) has been investigated in several studies but results are inconsistent. This may be due to different cohorts studied and the heterogeneity of their PD symptoms which impact the outcome of NW. This study aimed at determining predictive factors for a positive effect of NW on PD. Methodology and principal findings: Primary outcome was to define the baseline disease-associated and demographic parameters that distinguish patients who demonstrate improvement in the Unified PD rating scale (UPDRS) motor part following NW training ("U+") from those patients with no improvement after the same intervention ("U-"). The potentially predictive parameters were: age, age at onset, disease duration, gait velocity, step length, daily step number, UPDRS-motor part, Berg-Balance-Scale, Parkinson-Neuropsychometric-Dementia-Assessment, verbal-fluency-test and Becks-Depression-Inventory-II. Twenty-two PD patients (H&Y stage 2-2.5) performed twelve weeks of NW training. Eighteen patients were included in the final analysis. Overall, the UPDRS motor part did not improve significantly; however, eight patients had an improvement in the UPDRS motor part from baseline to end of study (U+). When comparing the potentially predictive factors of the 1J(+) cohort with those ten patients who did not improve (U-), there was a notable difference in gait velocity and step length, and showed a significant correlation with an improvement in the UDPRS motor part scores. Conclusion: Gait velocity and step length can predict the outcome of NW training as determined by the UPDRS motor part, indicating that PD patients with only slightly impaired gait performance benefit most. (c) 2015 Elsevier Ltd. All rights reserved.
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| 32. |
- Jansen, Iris E, et al.
(author)
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
- 2022
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In: Acta neuropathologica. - : Springer Science and Business Media LLC. - 1432-0533 .- 0001-6322. ; 144:5, s. 821-842
-
Journal article (peer-reviewed)abstract
- Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the European Alzheimer & Dementia Biobank (EADB), the largest collaborative effort on genetics underlying CSF biomarkers was established, including 31 cohorts with a total of 13,116 individuals (discovery n=8074; replication n=5042 individuals). Besides the APOE locus, novel associations with two other well-established AD risk loci were observed; CR1 was shown a locus for Aβ42 and BIN1 for pTau. GMNC and C16orf95 were further identified as loci for pTau, of which the latter is novel. Clustering methods exploring the influence of all known AD risk loci on the CSF protein levels, revealed 4 biological categories suggesting multiple Aβ42 and pTau related biological pathways involved in the etiology of AD. In functional follow-up analyses, GMNC and C16orf95 both associated with lateral ventricular volume, implying an overlap in genetic etiology for tau levels and brain ventricular volume.
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| 33. |
- Jungmalm, Jonatan, 1991, et al.
(author)
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Associations between biomechanical and clinical/anthropometrical factors and running-related injuries among recreational runners: a 52-week prospective cohort study.
- 2020
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In: Injury epidemiology. - : Springer Science and Business Media LLC. - 2197-1714. ; 7:1
-
Journal article (peer-reviewed)abstract
- The purpose of this exploratory study was to investigate whether runners with certain biomechanical or clinical/anthropometrical characteristics sustain more running-related injuries than runners with other biomechanical or clinical/anthropometrical characteristics.The study was designed as a prospective cohort with 52-weeks follow-up. A total of 224 injury-free, recreational runners were recruited from the Gothenburg Half Marathon and tested at baseline. The primary exposure variables were biomechanical and clinical/anthropometrical measures, including strength, lower extremity kinematics, joint range of motion, muscle flexibility, and trigger points. The primary outcome measure was any running-related injury diagnosed by a medical practitioner. Cumulative risk difference was used as measure of association. A shared frailty approach was used with legs as the unit of interest. A total of 448 legs were included in the analyses.The cumulative injury incidence proportion for legs was 29.0% (95%CI=24.0%; 34.8%). A few biomechanical and clinical/anthropometrical factors influence the number of running-related injuries sustained in recreational runners. Runners with a late timing of maximal eversion sustained 20.7% (95%CI=1.3; 40.0) more injuries, and runners with weak abductors in relation to adductors sustained 17.3% (95%CI=0.8; 33.7) more injuries, compared with the corresponding reference group.More injuries are likely to occur in runners with late timing of maximal eversion or weak hip abductors in relation to hip adductors.
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| 34. |
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| 35. |
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| 36. |
- Jungmalm, Jonatan, 1991, et al.
(author)
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Study protocol of a 52-week Prospective Running Injury study in Gothenburg (SPRING)
- 2018
-
In: BMJ Open Sport Exercise Medicine. - : BMJ. - 2044-6055 .- 2055-7647. ; 4:1
-
Journal article (peer-reviewed)abstract
- Introduction It is assumed that a running-related (overuse) injury occurs when a specific structure of the human body is exposed to a load that exceeds that structures’ load capacity. Therefore, monitoring training load is an important key to understanding the development of a running-related injury. Additionally, other distribution, magnitude and capacity-related factors should be considered when aiming to understand the causal chain of injury development. This paper presents a study protocol for a prospective cohort study that aims to add comprehensive information on the aetiology of running-related injuries and present a new approach for investigating changes in training load with regard to running-related injuries. Methods and analysis This study focused on recreational runners, that is, runners exposed to a minimum weekly average of 15 km for at least 1 year. Participants will undergo baseline tests consisting of a clinical/anthropometrical examination and biomechanical measurements. Furthermore, participants will log all training sessions in a diary on a weekly basis for 1 year. The primary exposure variable is changes in training load. A medical practitioner will examine runners suffering from running-related pain and, if possible, make a clear diagnosis. Finally, additional time-varying exposure variables will be included in the main analysis, whereas the analysis for the secondary purpose is based on timefixed baseline-related risk factors.
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| 37. |
- Lundberg Zachrisson, Andreas, 1987, et al.
(author)
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Athlete availability and incidence of overuse injuries over an athletics season in a cohort of elite Swedish athletics athletes - A prospective study
- 2020
-
In: Injury Epidemiology. - London : Springer Science and Business Media LLC. - 2197-1714. ; 7:1
-
Journal article (peer-reviewed)abstract
- Background: Athletics is a sport with a high incidence of injury, where most injuries are caused by overuse. Research on injury incidence and the occurrence of overuse injuries during a season in athletics is scarce. An athlete availability (unrestricted ability to participate in training or competition) of less than 80% has been linked with athletes being less likely to reach their performance goals. The purpose of this study was to estimate the monthly injury incidence rates, athlete availability, and the overuse injury incidence rate per 1000 athletics-hours of training in a cohort of Swedish elite athletics athletes. Methods: The cohort consisted of 59 male and female elite athletes competing in either middle or long-distance running, sprint, or jumping events. Injury and training data were collected during one athletics season, from October to the end of August. All injury data were collected by medical professionals. Training data were collected monthly, and consisted of event-specific training diaries covering training sessions, training days, and non-training or non-competition days. Monthly injury incidence rates were based on the number of new injuries per month in relation to the number of exposed (injury-free) athletes. Results: The overall injury incidence rate for all athletes was highest in October (22.0%). Monthly injury incidence rate for middle and long-distance runners was highest in October (26.1%), for sprinters in April (19.0%), and for jumpers in October (21.4%). The overall athlete availability was 78.0% for the cohort. Sprinters had the lowest athlete availability (71.4%), followed by jumpers (77.3%), and middle-distance and long-distance runners (82.7%). Female athletes (76.5%) had a lower athlete availability than male athletes (79.7%). The injury incidence rate was 1.81 injuries per 1000 athletics hours of training. Middle and long-distance runners had the highest injury incidence rate (2.38), followed by jumpers (1.62), and sprinters (1.34). Conclusion: Monthly injury incidence rates during a season appears to correspond to periods of high training volume (conditioning phases and training camps). The low overall athlete availability (> 80%) indicates that many Swedish elite athletes are less likely to reach their full potential. © 2020 The Author(s).
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| 38. |
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| 39. |
- Lundberg Zachrisson, Andreas, 1987, et al.
(author)
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Occurrence of overuse injuries in elite Swedish athletics—A prospective cohort study over one athletics season
- 2020
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In: Translational Sports Medicine. - : Hindawi Limited. - 2573-8488. ; 3:6, s. 649-656
-
Journal article (peer-reviewed)abstract
- The incidence proportion and severity of overuse injuries (OIs) in elite athletics are still unclear due to methodological limitations of prior studies. The aim was to pro-spectively measure OI incidence proportion, severity, and anatomic location during a complete Swedish elite athletics season. Seventy-five male and female elite ath-letes between 18 and 32 years of age, competing in either middle- and long-distance running, sprint, jumping, or throwing events were recruited. A medical professional diagnosed injuries during a physical examination. All injuries were classified as gradual or sudden onset incident injuries due to overuse. An athlete was considered injury free after reporting full return to training in their training documentation. The OI incidence proportion was 72.4% (95% CI: 60.8%, 84%), with 71 recorded injuries. Most injuries were severe, with 38% of them being moderately serious (8-28 days) and 36.6% serious (>28 days-6 months). The most common injury location was the thigh/hip at 41% followed by the foot/shank at 39%. The incidence proportion and severity of OIs were higher when medical professionals evaluated each athlete who developed symptoms, compared to self-reporting athletes. Future research should evaluate possible risk factors for OIs to try to lower the OI incidence proportion.
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| 40. |
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| 41. |
- Lundberg Zachrisson, Andreas, 1987, et al.
(author)
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Overuse injuries in Swedish elite athletics–a study protocol for a prospective multifactorial cohort study
- 2018
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In: BMC Musculoskeletal Disorders. - : Springer Science and Business Media LLC. - 1471-2474. ; 19, s. 1-12
-
Journal article (peer-reviewed)abstract
- Background: Overuse injuries (OI) are common in elite athletics. Previous studies have had athletes self-report injuries rather than having a medical professional provide a clear diagnosis. This might be a major reason for the inconsistencies in reported incident proportions of OI in elite athletics, in addition to the varying definitions of OI in current literature. Risk factors or combinations of risk factors (biomechanical, clinical, and training-related) have been shown to be important in the developmental process of OI. However, no studies have examined these relationships using a multifactorial and prospective approach in elite athletics. The purpose of this study protocol is to describe OI incidence proportion, injury severity, location, and occurrence during a complete athletics season. Moreover, possible discipline specific and injury specific risk factors that might be associated with OI will be examined. Methods: This study will be an explorative prospective cohort study including approximately 120 elite athletes. All athletes will be screened twice during one complete athletics season. The screening will consist of a body composition scan to measure muscle mass, fat free mass, lean mass, bone density, and bone mineral content. In addition, clinical examination will measure range of motion for the lower back, hip, knee, shoulder, and elbow and ankle joints. A running analysis will measure the 3D motions of the hip, knee, and ankle joints. Finally, maximal isometric strength tests of the main core and lower extremity muscles will be carried out. To record injuries, each athlete will consult a physiotherapist or sports medicine doctor affiliated with the study to get a clear diagnosis. Injury data will be recorded according to the previously published athletics consensus statement. Discussion: Results from this study protocol will contribute more insight and detailed knowledge regarding the extent of OI occurrence among elite athletes during a complete athletics season. It will also provide further insights into which risk factors are associated with the development of OI in elite athletics.
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| 42. |
- Lundberg Zachrisson, Andreas, 1987, et al.
(author)
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Risk factors for overuse injuries in a cohort of elite Swedish track and field athletes
- 2021
-
In: Bmc Sports Science Medicine and Rehabilitation. - London : Springer Science and Business Media LLC. - 2052-1847. ; 13:1
-
Journal article (peer-reviewed)abstract
- Background Most injuries in track and field are caused by overuse with conflicting reports concerning the underlying mechanisms. The purpose of this study was to evaluate how biomechanical and clinical factors relate to the risk of overuse injuries, and to investigate whether the relationships between potential risk factors and injury become stronger if injuries are grouped by location. Methods The study is a prospective cohort study conducted during a Swedish track and field season over eleven months, from October to August. The cohort consisted of elite male and female track and field athletes competing in either middle- and long-distance running, sprinting, jumping, or throwing events (n = 96). Athletes performed a baseline screening at enrollment consisting of a clinical examination, running, and strength tests. Injury data was collected during the season by medical professionals and divided according to their anatomical location into upper-body, thigh/hip, knee, or foot/shank injuries. Results Thirty-four (54.8%) injuries where located at the foot/shank, followed by sixteen injuries at the thigh/hip (25.8%). Only eight knee (12.9%) and four upper-body (6.5%) injuries were registered during the season and therefore not analysed. Effect sizes were calculated for all test variables. Small effect sizes (r(pb) = .10-.23) were found for eleven risk factors between the overall injured (all injuries combined) and non-injured athletes. By further sub-grouping the injured group into thigh/hip injuries, effect size increased in hip adduction range of motion knee flexion velocity and the muscle flexibility of the iliopsoas. For foot/shank injuries, only the hamstring:quadriceps strength ratios increased for the right side to a small effect size. Conclusions Injury grouping appears to increase effect size for certain risk factors. Athletes with a slower knee flexion velocity during stance phase were more likely to become injured (p-value <.03, r(pb) = .37). An increased cohort size to further sub-divide injuries into specific diagnoses is needed.
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| 43. |
- Perchthaler, Dennis, et al.
(author)
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Acute Effects of Whole-Body Vibration on Trunk and Neck Muscle Activity in Consideration of Different Vibration Loads
- 2015
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In: Journal of Sports Science and Medicine. - 1303-2968. ; 14:1, s. 155-162
-
Journal article (peer-reviewed)abstract
- The intention of this study was to systematically analyze the impact of biomechanical parameters in terms of different peakto- peak displacements and knee angles on trunk and neck muscle activity during whole-body vibration (WBV). 28 healthy men and women (age 23 ± 3 years) performed four static squat positions (2 peak-to-peak displacements x 2 knee angles) on a side alternating vibration platform with and without vibration stimulus. Surface electromyography (EMG) was used to record the neuromuscular activity of the erector spinae muscle, the rectus abdominis muscle, and of the splenius muscle. EMG levels normalized to maximal voluntary contractions ranged between 3.2 – 27.2 % MVC during WBV. The increase in muscle activity caused by WBV was significant, particularly for the back muscles, which was up to 19.0 % MVC. The impact of the factor ‘condition’ (F-values ranged from 13.4 to 132.0, p ≤ 0.001) and of the factor ‘peak-to-peak displacement’ (F-values ranged from 6.4 to 69.0 and p-values from < 0.001 to 0.01) were statistically significant for each muscle tested. However, the factor ‘knee angle’ only affected the back muscles (F-value 10.3 and 7.3, p ≤ 0.01). The results of this study should give more information for developing effective and safe training protocols for WBV treatment of the upper body.
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| 44. |
- Perchthaler, Dennis, et al.
(author)
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Evaluation of a six-week whole-body vibration intervention on neuromuscular performance in older adults
- 2015
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In: Journal of Strength and Conditioning Research. - 1064-8011. ; 29:1
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Research review (peer-reviewed)abstract
- Perchthaler, D, Grau, S, and Hein, T. Evaluation of a 6-week whole-body vibration intervention on neuromuscular performance in older adults. J Strength Cond Res 29(1): 86–95, 2015—Research in the field of whole-body vibration (WBV) for the enhancement of neuromuscular performance is becoming increasingly popular. However, additional understanding of optimal WBV training protocols is still necessary to develop optimal and effective training and prevention concepts, especially for elderly people. The intention of this study was to evaluate a 6-week WBV intervention program based on optimal vibration loads adapted from the literature on lower-limb strength parameters and performance, as well as on perceived exertion according to a subjective rating. A total of 21 older adults were allocated randomly into either a WBV training or control group (CO). Before and after the intervention period, jump height was measured during a countermovement jump. In addition, isolated isokinetic maximal knee extension and flexion strength, mean power, and work were recorded using a motordriven dynamometer. Borg’s scale for rating of perceived exertion was used to evaluate the intensity of WBV exercises within each training session. After the intervention period, jump height increased by 18.55% (p , 0.001) in the WBV group, whereas values of the CO remained unchanged. There were no statistically significant differences in isokinetic maximal strength, mean power, or work values in knee extension or flexion (all p . 0.05). Finally, the subjective perceived exertion of the WBV exercises and respective training parameters ranged between moderate rating levels of 7 and 13 of Borg’s scale. Our data show that WBV is a feasible and safe training program for elderly people to increase multijoint strength performance of the lower limbs during a countermovement jump. This could help to determine the potential of WBV programs in training of the elderly to prevent age-related reduction of neuromuscular performance.
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| 45. |
- Pfeiffer, Dorothea, et al.
(author)
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Genetic Imbalance Is Associated With Functional Outcome After Ischemic Stroke
- 2019
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In: Stroke. - 1524-4628. ; 50:2, s. 298-304
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Journal article (peer-reviewed)abstract
- Background and Purpose- We sought to explore the effect of genetic imbalance on functional outcome after ischemic stroke (IS). Methods- Copy number variation was identified in high-density single-nucleotide polymorphism microarray data of IS patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) and SiGN (Stroke Genetics Network)/GISCOME (Genetics of Ischaemic Stroke Functional Outcome) networks. Genetic imbalance, defined as total number of protein-coding genes affected by copy number variations in an individual, was compared between patients with favorable (modified Rankin Scale score of 0-2) and unfavorable (modified Rankin Scale score of ≥3) outcome after 3 months. Subgroup analyses were confined to patients with imbalance affecting ohnologs-a class of dose-sensitive genes, or to those with imbalance not affecting ohnologs. The association of imbalance with outcome was analyzed by logistic regression analysis, adjusted for age, sex, stroke subtype, stroke severity, and ancestry. Results- The study sample comprised 816 CADISP patients (age 44.2±10.3 years) and 2498 SiGN/GISCOME patients (age 67.7±14.2 years). Outcome was unfavorable in 122 CADISP and 889 SiGN/GISCOME patients. Multivariate logistic regression analysis revealed that increased genetic imbalance was associated with less favorable outcome in both samples (CADISP: P=0.0007; odds ratio=0.89; 95% CI, 0.82-0.95 and SiGN/GISCOME: P=0.0036; odds ratio=0.94; 95% CI, 0.91-0.98). The association was independent of age, sex, stroke severity on admission, stroke subtype, and ancestry. On subgroup analysis, imbalance affecting ohnologs was associated with outcome (CADISP: odds ratio=0.88; 95% CI, 0.80-0.95 and SiGN/GISCOME: odds ratio=0.93; 95% CI, 0.89-0.98) whereas imbalance without ohnologs lacked such an association. Conclusions- Increased genetic imbalance was associated with poorer functional outcome after IS in both study populations. Subgroup analysis revealed that this association was driven by presence of ohnologs in the respective copy number variations, suggesting a causal role of the deleterious effects of genetic imbalance.
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| 46. |
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| 47. |
- Rapp, W., et al.
(author)
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Improvement of walking speed and gait symmetry in older patients after hip arthroplasty: a prospective cohort study
- 2015
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In: Bmc Musculoskeletal Disorders. - : Springer Science and Business Media LLC. - 1471-2474. ; 16
-
Journal article (peer-reviewed)abstract
- Background: Retraining walking in patients after hip or knee arthroplasty is an important component of rehabilitation especially in older persons whose social interactions are influenced by their level of mobility. The objective of this study was to test the effect of an intensive inpatient rehabilitation program on walking speed and gait symmetry in patients after hip arthroplasty (THA) using inertial sensor technology. Methods: Twenty-nine patients undergoing a 4-week inpatient rehabilitation program following THA and 30 age-matched healthy subjects participated in this study. Walking speed and gait symmetry parameters were measured using inertial sensor device for standardized walking trials (2*20.3 m in a gym) at their self-selected normal and fast walking speeds on postoperative days 15, 21, and 27 in patients and in a single session in control subjects. Walking speed was measured using timing lights. Gait symmetry was determined using autocorrelation calculation of the cranio-caudal (CC) acceleration signals from an inertial sensor placed at the lower spine. Results: Walking speed and gait symmetry improved from postoperative days 15-27 (speed, female: 3.2 and 4.5 m/s; male: 4.2 and 5.2 m/s; autocorrelation, female: 0.77 and 0.81; male: 0.70 and 0.79; P < 0.001 for all). After the 4-week rehabilitation program, walking speed and gait symmetry were still lower than those in control subjects (speed, female 4.5 m/s vs. 5.7 m/s; male: 5.2 m/s vs. 5.3 m/s; autocorrelation, female: 0.81 vs. 0.88; male: 0.79 vs. 0.90; P < 0.001 for all). Conclusions: While patients with THA improved their walking capacity during a 4-week inpatient rehabilitation program, subsequent intensive gait training is warranted for achieving normal gait symmetry. Inertial sensor technology may be a useful tool for evaluating the rehabilitation process during the post-inpatient period.
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| 48. |
- Regmi, P., et al.
(author)
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The future of WRRF modelling - Outlook and challenges
- 2019
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In: Water Science and Technology. - : IWA Publishing. - 0273-1223 .- 1996-9732. ; 79:1, s. 3-14
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Journal article (peer-reviewed)abstract
- The wastewater industry is currently facing dramatic changes, shifting away from energy-intensive wastewater treatment towards low-energy, sustainable technologies capable of achieving energy positive operation and resource recovery. The latter will shift the focus of the wastewater industry to how one could manage and extract resources from the wastewater, as opposed to the conventional paradigm of treatment. Debatable questions arise: Can the more complex models be calibrated, or will additional unknowns be introduced? After almost 30 years using well-known International Water Association (IWA) models, should the community move to other components, processes, or model structures like 'black box' models, computational fluid dynamics techniques, etc.? Can new data sources - e.g. on-line sensor data, chemical and molecular analyses, new analytical techniques, off-gas analysis - keep up with the increasing process complexity? Are different methods for data management, data reconciliation, and fault detection mature enough for coping with such a large amount of information? Are the available calibration techniques able to cope with such complex models? This paper describes the thoughts and opinions collected during the closing session of the 6th IWA/WEF Water Resource Recovery Modelling Seminar 2018. It presents a concerted and collective effort by individuals from many different sectors of the wastewater industry to offer past and present insights, as well as an outlook into the future of wastewater modelling.
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