| 1. |
- Agerberth, B, et al.
(författare)
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FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
- 1995
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 92:1, s. 195-9
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Tidskriftsartikel (refereegranskat)abstract
- PR-39, a proline/arginine-rich peptide antibiotic, has been purified from pig intestine and later shown to originate in the bone marrow. Intending to isolate a clone for a human counterpart to PR-39, we synthesized a PCR probe derived from the PR-39 gene. However, when this probe was used to screen a human bone marrow cDNA library, eight clones were obtained with information for another putative human peptide antibiotic, designated FALL-39 after the first four residues. FALL-39 is a 39-residue peptide lacking cysteine and tryptophan. All human peptide antibiotics previously isolated (or predicted) belong to the defensin family and contain three disulfide bridges. The clone for prepro-FALL-39 encodes a cathelin-like precursor protein with 170 amino acid residues. We have postulated a dibasic processing site for the mature FALL-39 and chemically synthesized the putative peptide. In basal medium E, synthetic FALL-39 was highly active against Escherichia coli and Bacillus megaterium. Residues 13-34 in FALL-39 can be predicted to form a perfect amphiphatic helix, and CD spectra showed that medium E induced 30% helix formation in FALL-39. RNA blot analyses disclosed that the gene for FALL-39 is expressed mainly in human bone marrow and testis.
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| 8. |
- Brenning, Nils, et al.
(författare)
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Critical ionization velocity interaction in the CRIT I rocket experiment
- 1990
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Ingår i: Advances in Space Research. - : Elsevier BV. - 0273-1177. ; 10, s. 63-66
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Tidskriftsartikel (refereegranskat)abstract
- In the rocket experiment CRIT I, launched from Wallops Island on 13 May 1986, two identical Barium shaped charges were fired from distances of 1.3 km and 3.6 km towards the main experiment payload, which was separated from a sub-payload by a couple of km along the magnetic field. The relevance of earlier proposed mechanisms for electron heating in ionospheric critical velocity experiments is investigated in the light of the CRIT I results. It is concluded that both the "homogeneous" and the "ionizing front" models can be applied, in different parts of the stream. It is also possible that a third, entirely different, mechanism may contribute to the electron heating. This mechanism involves direct energization of electrons in the magnetic-field-aligned component of the DC electric field. © 1989.
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| 9. |
- Brenning, Nils, et al.
(författare)
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Electrodynamic interaction between the CRIT I ionized barium streams and the ambient ionosphere
- 1990
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Ingår i: Advances in Space Research. - : Elsevier BV. - 0273-1177. ; 10, s. 67-70
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Tidskriftsartikel (refereegranskat)abstract
- In the CRIT I Critical Velocity experiment, launched from Wallops Island on 13 May, 1986, two fast barium streams were ejected by means of shaped charges. Their electrodynamic interaction with the ambient ionosphere is discussed. An outstanding feature of the DC electric field observed within the streams was a large magnetic-field-aligned component, persisting on the time scale of the passage of the streams. One interpretation of the DC electric field data is that the internal electric fields of the streams is not greatly modified by Birkeland currents, i.e. a state is established, where the transverse currents are to a first approximation divergence-free. It is argued that this interpretation can explain why a reversal of the strong explosion-directed electric field was observed in the first explosion but not in the second (more distant one). © 1989.
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| 10. |
- Brenning, Nils, et al.
(författare)
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Interpretation of the Electric Fields Measured in an Ionospheric Critical Ionization Velocity Experiment
- 1991
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Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 96, s. 9719-9733
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Tidskriftsartikel (refereegranskat)abstract
- This paper deals with the quasi-dc electric fields measured in the CRIT I ionospheric release experiment, which was launched from Wallops Island on May 13, 1986. The purpose of the experiment was to study the critical ionization velocity (CIV) mechanism in the ionosphere. Two identical barium shaped charges were fired from distances of 1.99 km and 4.34 km towards a main payload, which made full three-dimensional measurements of the electric field inside the streams. There was also a subpayload separated from the main payload by a couple of kilometers along the magnetic field. The relevance of earlier proposed mechanisms for electron heating in CIV is investigated in the light of the CRIT I results. It is concluded that both the “homogeneous” and the “ionizing front” models probably apply, but in different parts of the stream. It is also possible that electrons are directly accelerated by a magnetic-field-aligned component of the electric field; the quasi-dc electric field observed within the streams had a large magnetic-field-aligned component, persisting on the time scale of the passage of the streams. The coupling between the ambient ionosphere and the ionized barium stream in CRIT I was more complicated than is usually assumed in CIV theories, with strong magnetic-field-aligned electric fields and probably current limitation as important processes. One interpretation of the quasi-dc electric field data is that the internal electric fields of the streams were not greatly modified by magnetic-field-aligned currents, i.e., a state was established where the transverse currents were to a first approximation divergence-free. It is argued that this interpretation can explain both a reversal of the strong explosion-directed electric field in burst 1 and the absence of such a reversal in burst 2.
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| 11. |
- Fredriksson-Larsson, Ulla, 1962, et al.
(författare)
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The single-item measure of stress after myocardial infarction and its association with fatigue
- 2015
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Ingår i: Open Journal of Nursing. - : Scientific Research Publishing, Inc.. - 2162-5336 .- 2162-5344. ; 5:4, s. 345-353
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Tidskriftsartikel (refereegranskat)abstract
- Surviving a myocardial infarction (MI) can be a stressful event entailing challenges in daily life during the recovery period. Experiencing fatigue symptoms post-MI has been described as bothersome and occurs in nearly half of patients four months and two years after MI. The aetiology of fatigue disorder is unclear, but research has shown that fatigue plays an important role in the relationship between stress and perceived poor health. Previous findings indicate that having access to an easily administered stress measurement is worthwhile both in the clinic and in research. The single-item measure of stress symptoms has not been validated in persons treated for MI. The aim was to validate the single-item measure of stress symptoms and to explore its association with fatigue in a sample of persons treated for MI. Methods: 142 respondents completed the questionnaires of the Multidimensional Fatigue Inventory-20, the single-item measure of stress symptoms and the Perceived Stress Scale-10 (PPS-10) two months post-MI. Correlation analysis and t-tests were used to validate the single-item stress measure and its association with post-MI fatigue. Results: The convergent validity of the single-item measure of stress symptoms was confirmed. In analyses of relations between stress and fatigue, it was found that the single-item stress measure was strongly associated with both the global fatigue score and all four fatigue dimension scores (general, physical and mental fatigue as well as reduced activity). Conclusion: The single-item measure of stress symptoms was found to be a valid measure of post-MI stress. Also, the measure was useful in assessing associations between stress and fatigue and could therefore indicate that post-MI fatigue experiences should be further explored in full using multidimensional fatigue assessment.
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| 12. |
- Fredriksson-Larsson, Ulla, et al.
(författare)
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The single-item measure of stress symptoms after myocardial infarction and its association with fatigue.
- 2015
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Ingår i: Open Journal of Nursing. - : Scientific Research Publishing, Inc.. - 2162-5336 .- 2162-5344. ; 5, s. 345-353
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Tidskriftsartikel (refereegranskat)abstract
- Surviving a myocardial infarction (MI) can be a stressful event entailing challenges in daily life during the recovery period. Experiencing fatigue symptoms post-MI has been described as bothersome and occurs in nearly half of patients four months and two years after MI. The aetiology of fatigue disorder is unclear, but research has shown that fatigue plays an important role in the relationship between stress and perceived poor health. Previous findings indicate that having access to an easily administered stress measurement is worthwhile both in the clinic and in research. The single-item measure of stress symptoms has not been validated in persons treated for MI. The aim was to validate the single-item measure of stress symptoms and to explore its association with fatigue in a sample of persons treated for MI. Methods: 142 respondents completed the questionnaires of the Multidimensional Fatigue Inventory-20, the single-item measure of stress symptoms and the Perceived Stress Scale-10 (PPS-10) two months post-MI. Correlation analysis and t-tests were used to validate the single-item stress measure and its association with post-MI fatigue. Results: The convergent validity of the single-item measure of stress symptoms was confirmed. In analyses of relations between stress and fatigue, it was found that the single-item stress measure was strongly associated with both the global fatigue score and all four fatigue dimension scores (general, physical and mental fatigue as well as reduced activity). Conclusion: The single-item measure of stress symptoms was found to be a valid measure of post-MI stress. Also, the measure was useful in assessing associations between stress and fatigue and could therefore indicate that post-MI fatigue experiences should be further explored in full using multidimensional fatigue assessmen
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| 13. |
- Gustafsson, Georg, et al.
(författare)
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First results of electric field and density observations by Cluster EFW based on initial months of operation
- 2001
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Ingår i: Annales Geophysicae. - : Copernicus GmbH. - 0992-7689 .- 1432-0576. ; 19:12-okt, s. 1219-1240
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Tidskriftsartikel (refereegranskat)abstract
- Highlights are presented from studies of the electric field data from various regions along the CLUSTER orbit. They all point towards a very high coherence for phenomena recorded on four spacecraft that are separated by a few hundred kilometers for structures over the whole range of apparent frequencies from I mHz to 9 kHz. This presents completely new opportunities to study spatial-temporal plasma phenomena from the magnetosphere out to the solar wind. A new probe environment was constructed for the CLUSTER electric field experiment that now produces data of unprecedented quality. Determination of plasma flow in the solar wind is an example of the capability of the instrument.
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| 14. |
- Harvey, P, et al.
(författare)
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The electric field instrument on the Polar satellite
- 1995
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Ingår i: Space Science Reviews. - 0038-6308 .- 1572-9672. ; 71, s. 583-596
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Tidskriftsartikel (refereegranskat)abstract
- The Polar satellite carries a system of four wire booms in the spacecraft spin plane and two rigid booms along the spin axis. Each of the booms has a spherical sensor at its tip along with nearby guard and stub surfaces whose potentials relative to that of their sphere are controlled by associated electronics. The potential differences between opposite sphere pairs are measured to yield the three components of the DC to >1 MHz electric field. Spheres can also be operated in a mode in which their collected current is measured to give information on the plasma density and its fluctuations. The scientific studies to be performed by this experiment as well as the mechanical and electrical properties of the detector system are described.
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| 17. |
- Lindh, T, et al.
(författare)
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Tooth-implant supported fixed prostheses : A retrospective multicenter study
- 2001
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Ingår i: International Journal of Prosthodontics. - 0893-2174 .- 1139-9791. ; 14:4, s. 321-328
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The purpose of this retrospective multicenter study on implants combined with natural teeth was to investigate the implant survival rate and loss of marginal bone, as well as indications and complications pertinent to this form of implant therapy. Materials and Methods: The study comprised 185 implants in 111 patients from six different clinics in Sweden. Gathering of data, which were taken from patient records, followed a strict protocol. The registrations included indications for treatment, failure of implants, radiographs from baseline and follow-up, and information on complications. Results: The cumulative implant survival was found to be 95.4% (standard error 4.5%) up to 3 years of follow-up. The marginal bone level at baseline was lower in the maxilla compared with the mandible (P = .015), but any further loss did not differ between the jaws. The most severe complication other than loss of osseointegration (6/185) or periimplant infections (4/183) was intrusion of the abutment teeth, which occurred in 5% of the cases. In all instances, the intrusion was seen in constructions with nonrigid forms of connection between the implants and teeth. Conclusion: The tooth-implant supported prosthesis using the Branemark system is in the short term an equally predictable treatment as the completely implant-supported prosthesis concerning implant survival and loss of marginal bone. When combining implants and teeth, a rigid form of connection should be used to prevent tooth intrusion.
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