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Sökning: WFRF:(Gustavsson Andreas)

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1.
  • Gustavsson, Andreas, 1982- (författare)
  • Static Execution Time Analysis of Parallel Systems
  • 2016
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The past trend of increasing processor throughput by increasing the clock frequency and the instruction level parallelism is no longer feasible due to extensive power consumption and heat dissipation. Therefore, the current trend in computer hardware design is to expose explicit parallelism to the software level. This is most often done using multiple, relatively slow and simple, processing cores situated on a single processor chip. The cores usually share some resources on the chip, such as some level of cache memory (which means that they also share the interconnect, e.g., a bus, to that memory and also all higher levels of memory). To fully exploit this type of parallel processor chip, programs running on it will have to be concurrent. Since multi-core processors are the new standard, even embedded real-time systems will (and some already do) incorporate this kind of processor and concurrent code.A real-time system is any system whose correctness is dependent both on its functional and temporal behavior. For some real-time systems, a failure to meet the temporal requirements can have catastrophic consequences. Therefore, it is crucial that methods to derive safe estimations on the timing properties of parallel computer systems are developed, if at all possible.This thesis presents a method to derive safe (lower and upper) bounds on the execution time of a given parallel system, thus showing that such methods must exist. The interface to the method is a small concurrent programming language, based on communicating and synchronizing threads, that is formally (syntactically and semantically) defined in the thesis. The method is based on abstract execution, which is itself based on abstract interpretation techniques that have been commonly used within the field of timing analysis of single-core computer systems, to derive safe timing bounds in an efficient (although, over-approximative) way. The thesis also proves the soundness of the presented method (i.e., that the estimated timing bounds are indeed safe) and evaluates a prototype implementation of it.
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2.
  • Gustavsson, Andreas, 1982- (författare)
  • Static Timing Analysis of Parallel Systems Using Abstract Execution
  • 2014
  • Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The Power Wall has stopped the past trend of increasing processor throughput by increasing the clock frequency and the instruction level parallelism.Therefore, the current trend in computer hardware design is to expose explicit parallelism to the software level.This is most often done using multiple processing cores situated on a single processor chip.The cores usually share some resources on the chip, such as some level of cache memory (which means that they also share the interconnect, e.g. a bus, to that memory and also all higher levels of memory), and to fully exploit this type of parallel processor chip, programs running on it will have to be concurrent.Since multi-core processors are the new standard, even embedded real-time systems will (and some already do) incorporate this kind of processor and concurrent code.A real-time system is any system whose correctness is dependent both on its functional and temporal output. For some real-time systems, a failure to meet the temporal requirements can have catastrophic consequences. Therefore, it is of utmost importance that methods to analyze and derive safe estimations on the timing properties of parallel computer systems are developed.This thesis presents an analysis that derives safe (lower and upper) bounds on the execution time of a given parallel system.The interface to the analysis is a small concurrent programming language, based on communicating and synchronizing threads, that is formally (syntactically and semantically) defined in the thesis.The analysis is based on abstract execution, which is itself based on abstract interpretation techniques that have been commonly used within the field of timing analysis of single-core computer systems, to derive safe timing bounds in an efficient (although, over-approximative) way.Basically, abstract execution simulates the execution of several real executions of the analyzed program in one go.The thesis also proves the soundness of the presented analysis (i.e. that the estimated timing bounds are indeed safe) and includes some examples, each showing different features or characteristics of the analysis.
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3.
  • Gustavsson, Andreas, et al. (författare)
  • Towards WCET Analysis of Multicore Architectures using UPPAAL
  • 2010
  • Ingår i: OpenAccess Series in Informatics, vol. 15, 2010. - 9783939897217 ; , s. 101-112
  • Konferensbidrag (refereegranskat)abstract
    • To take full advantage of the increasingly used shared-memory multicore architectures, software algorithms will need to be parallelized over multiple threads. This means that threads will have to share resources (e.g. some level of cache) and communicate and synchronize with each other. There already exist software libraries (e.g. OpenMP) used to explicitly parallelize available sequential C/C++ and Fortran code, which means that parallel code could be easily obtained. To be able to use parallel software running on multicore architectures in embedded systems with hard real-time constraints, new WCET (Worst-Case Execution Time) analysis methods and tools must be developed. This paper investigates a method based on model-checking a system of timed automata using the UPPAAL tool box. It is found that it is possible to perform WCET analysis on (not too large and complex) parallel systems using UPPAAL. We also show how to model thread synchronization using spinlock-like primitives.
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4.
  • Hellsmark, Hans, 1974, et al. (författare)
  • Teknologiska innovationssystem inom energiområdet: En praktisk vägledning till identifiering av systemsvagheter som motiverar särskilda politiska åtaganden
  • 2014
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Syftet med denna rapport är att illustrera hur ett praktiskt inriktat ramverk, tekno- logiska innovationssystem (TIS), kan användas av analytiker och beslutsfattare vid departement och myndigheter för att analysera strategiskt viktiga teknikområden ?????????????????????????????????????????????????????????????????????????????I rapporten analyseras fem TIS centrerade kring havsbaserad vindkraft, marin energi, ????????????????????????????????????????????????????????????????????????????????????? systemsvagheter som bromsar områdets vidare utveckling, vilka som kan åtgärdas av systemets aktörer och vilka som motiverar särskilda politiska åtaganden. Rapporten utgör därmed ett underlag för att formulera åtgärder för att åstadkomma ökad innova- tion, teknikspridning och industrialisering inom ovan nämnda teknikområden.Studien har även möjliggjort en jämförande analys av likheter och skillnader ???????????????????????????????????????????????????????????????????????????????? ?????????????????????????????????????????????????????????????????????????????????????? mellan områdena – de är starka respektive svaga av olika orsaker. Detta visar att ???????????????????????????????????????????????????????????????????????Samtidigt har områdena gemensamma drag. Systemets aktörer, där även politiska ???????????????????????????????????????????????????????????????????????????????????? ?????????????????????????????????????????????????????????????????????????????- skapsnätverk. Men de har varit sämre på att skapa tidiga nischmarknader som ger utrymme för fortsatt lärande och kostnadsreduktion. Sådana nischer kan ibland skapas av marknadens aktörer, men ofta krävs politiska styrmedel. De behövs för att investeringar i kunskapsutveckling ska kunna nyttiggöras och för att en bred industriell utveckling inom nya områden skall göras möjlig i Sverige.Vidare presenteras lärdomar kring vad en aktiv teknikpolitik innebär. Två huvud- ??????????????????????????????????????????????????????????????????????????????- hällsbygget och därför bör vara ett politikområde bland många samt att den skarpa ??????????????????????????????????????????????????????????????????????????????- ?????????????????????????????????????????????????????????????????????????????????? ?????????????????????????????????????????????????????????????????????????????????? olika faser av innovationssystemets utveckling.För att lyckas med en aktiv teknikpolitik behövs en hög grad av koordinering ??????????????????????????????????????????????????????????????????????? teknikområden så att ”rätt” typ av åtgärder kan sättas in vid ”rätt” tidpunkt av ”rätt” aktör. TIS-ramverket lyfts här fram som en metod för att skapa ett sådant underlag. Slutligen presenteras en metod för projektbedömningar som syftar till att stötta handläggare i utvärderingar av projekt inom nya teknikområden.Rapporten i sin helhet riktar sig särskilt till beslutsfattare och handläggare vid myndigheter, departement och politiker, men även andra organisationer och indi- vider med intresse av att högt ställda klimatmål ska kunna nås samtidigt som en positiv näringslivsutveckling möjliggörs.
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6.
  • Agemark, Maria, et al. (författare)
  • Reconstitution of water channel function and 2D-crystallization of human aquaporin 8.
  • 2012
  • Ingår i: Biochimica et Biophysica Acta. - : Elsevier BV. - 0006-3002 .- 0005-2736. ; 1818:3, s. 839-850
  • Tidskriftsartikel (refereegranskat)abstract
    • Among the thirteen human aquaporins (AQP0-12), the primary structure of AQP8 is unique. By sequence alignment it is evident that mammalian AQP8s form a separate subfamily distinct from the other mammalian aquaporins. The constriction region of the pore determining the solute specificity deviates in AQP8 making it permeable to both ammonia and H(2)O(2) in addition to water. To better understand the selectivity and gating mechanism of aquaporins, high-resolution structures are necessary. So far, the structure of one human aquaporin (HsAQP5) has been solved at atomic resolution. For mammalian aquaporins in general, high-resolution structures are only available for those belonging to the water-specific subfamily (including HsAQP5). Thus, it is of interest to solve structures of other aquaporin subfamily members with different solute specificities. To achieve this the aquaporins need to be overexpressed heterologously and purified. Here we use the methylotrophic yeast Pichia pastoris as a host for the overexpression. A wide screen of different detergents and detergent-lipid combinations resulted in the solubilization of functional human AQP8 protein and in well-ordered 2D crystals. It also became evident that removal of amino acids constituting affinity tags was crucial to achieve highly ordered 2D crystals diffracting to 3Å.
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7.
  • Ahlberg, Carl, et al. (författare)
  • The Black Pearl: An Autonomous Underwater Vehicle
  • 2013
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • The Black Pearl is a custom made autonomous underwater vehicle developed at Mälardalen University, Sweden. It is built in a modular fashion, including its mechanics, electronics and software. After a successful participation at the RoboSub competition in 2012 and winning the prize for best craftsmanship, this year we made minor improvements to the hardware, while the focus of the robot's evolution shifted to the software part. In this paper we give an overview of how the Black Pearl is built, both from the hardware and software point of view.
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9.
  • Al-Adili, Ali, et al. (författare)
  • Analysis of prompt fission neutrons in U-235(nth,f) and fission fragment distributions for the thermal neutron induced fission of U-234
  • 2016
  • Ingår i: CNR*15 - 5th International Workshop On Compound-Nuclear Reactions And Related Topics. - : EDP Sciences.
  • Konferensbidrag (refereegranskat)abstract
    • This paper presents the ongoing analysis of two fission experiments. Both projects are part of the collaboration between the nuclear reactions group at Uppsala and the JRC-IRMM. The first experiment deals with the prompt fission neutron multiplicity in the thermal neutron induced fission of U-235(n,f). The second, on the fission fragment properties in the thermal fission of U-234(n,f). The prompt fission neutron multiplicity has been measured at the JRC-IRMM using two liquid scintillators in coincidence with an ionization chamber. The first experimental campaign focused on U-235(nth,f) whereas a second experimental campaign is foreseen later for the same reaction at 5.5 MeV. The goal is to investigate how the so-called saw-tooth shape changes as a function of fragment mass and excitation energy. Some harsh experimental conditions were experienced due to the large radiation background. The solution to this will be discussed along with preliminary results. In addition, the analysis of thermal neutron induced fission of U-234(n,f) will be discussed. Currently analysis of data is ongoing, originally taken at the ILL reactor. The experiment is of particular interest since no measurement exist of the mass and energy distributions for this system at thermal energies. One main problem encountered during analysis was the huge background of U-235(nth, f). Despite the negligible isotopic traces in the sample, the cross section difference is enormous. Solution to this parasitic background will be highlighted.
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10.
  • Al-Adili, Ali, et al. (författare)
  • Fission Activities of the Nuclear Reactions Group in Uppsala
  • 2015
  • Ingår i: Scientific Workshop on Nuclear Fission Dynamics and the Emission of Prompt Neutrons and Gamma Rays, THEORY-3. - : Elsevier BV. ; , s. 145-149
  • Konferensbidrag (refereegranskat)abstract
    • This paper highlights some of the main activities related to fission of the nuclear reactions group at Uppsala University. The group is involved for instance in fission yield experiments at the IGISOL facility, cross-section measurements at the NFS facility, as well as fission dynamics studies at the IRMM JRC-EC. Moreover, work is ongoing on the Total Monte Carlo (TMC) methodology and on including the GEF fission code into the TALYS nuclear reaction code. Selected results from these projects are discussed.
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11.
  • Al-Adili, Ali, et al. (författare)
  • Ion counting efficiencies at the IGISOL facility
  • 2014
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • At the IGISOL-JYFLTRAP facility, fission mass yields can be studied at high precision. Fission fragments from a U target are passing through a Ni foil and entering a gas filled chamber. The collected fragments are guided through a mass separator to a Penning trap where their masses are identified. This simulation work focuses on how different fission fragment properties (mass, charge and energy) affect the stopping efficiency in the gas cell. In addition, different experimental parameters are varied (e. g. U and Ni thickness and He gas pressure) to study their impact on the stopping efficiency. The simulations were performed using the Geant4 package and the SRIM code. The main results suggest a small variation in the stopping efficiency as a function of mass, charge and kinetic energy. It is predicted that heavy fragments are stopped about 9% less efficiently than the light fragments. However it was found that the properties of the U, Ni and the He gas influences this behavior. Hence it could be possible to optimize the efficiency.
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12.
  • Al-Adili, Ali, et al. (författare)
  • Neutron-multiplicity experiments for enhanced fission modelling
  • 2017
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 9782759890200
  • Konferensbidrag (refereegranskat)abstract
    • The nuclear de-excitation process of fission fragments (FF) provides fundamental information for the understanding of nuclear fission and nuclear structure in neutron-rich isotopes. The variation of the prompt-neutron multiplicity, ν(A), as a function of the incident neutron energy (En) is one of many open questions. It leads to significantly different treatments in various fission models and implies that experimental data are analyzed based on contradicting assumptions. One critical question is whether the additional excitation energy (Eexc) is manifested through an increase of ν(A) for all fragments or for the heavy ones only. A systematic investigation of ν(A) as a function of En has been initiated. Correlations between prompt-fission neutrons and fission fragments are obtained by using liquid scintillators in conjunction with a Frisch-grid ionization chamber. The proof-of-principle has been achieved on the reaction 235U(nth,f) at the Van De Graff (VdG) accelerator of the JRC-Geel using a fully digital data acquisition system. Neutrons from 252Cf(sf) were measured separately to quantify the neutron-scattering component due to surrounding shielding material and to determine the intrinsic detector efficiency. Prelimenary results on ν(A) and spectrum in correlation with FF properties are presented.
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13.
  • Al-Adili, Ali, et al. (författare)
  • Simulations of the fission-product stopping efficiency in IGISOL
  • 2015
  • Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 51:59, s. 1-7
  • Tidskriftsartikel (refereegranskat)abstract
    • At the Jyväskylä Ion Guide Isotope Separator On-Line (IGISOL) facility, independent fission yields are measured employing the Penning-trap technique. Fission products are produced, e.g. by impinging protons on a uranium target, and are stopped in a gas-filled chamber. The products are collected by a flow of He gas and guided through a mass separator to a Penning trap, where their masses are identified. This work investigates how fission-product properties, such as mass and energy, affect the ion stopping efficiency in the gas cell. The study was performed using the Geant4 toolkit and the SRIM code. The main results show a nearly mass-independent ion stopping with regard to the wide spread of ion masses and energies, with a proper choice of uranium target thickness. Although small variations were observed, in the order of 5%, the results are within the systematic uncertainties of the simulations. To optimize the stopping efficiency while reducing the systematic errors, different experimental parameters were varied; for instance material thicknesses and He gas pressure. Different parameters influence the mass dependence and could alter the mass dependencies in the ion stopping efficiency.
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14.
  • Al-Adili, Ali, et al. (författare)
  • Studying fission neutrons with 2E-2v and 2E
  • 2018
  • Ingår i: SCIENTIFIC WORKSHOP ON NUCLEAR FISSION DYNAMICS AND THE EMISSION OF PROMPT NEUTRONS AND GAMMA RAYS (THEORY-4). - : EDP Sciences. - 9782759890316
  • Konferensbidrag (refereegranskat)abstract
    • This work aims at measuring prompt-fission neutrons at different excitation energies of the nucleus. Two independent techniques, the 2E-2v and the 2E techniques, are used to map the characteristics of the mass-dependent prompt fission neutron multiplicity, 7(A), when the excitation energy is increased. The VERDI 2E-2v spectrometer is being developed at JRC-GEEL. The Fission Fragment (FF) energies are measured using two arrays of 16 silicon (Si) detectors each. The FFs velocities are obtained by time-of-flight, measured between micro-channel plates (MCP) and Si detectors. With MCPs placed on both sides of the fission source, VERDI allows for independent timing measurements for both fragments. Cf-252(sf) was measured and the present results revealed particular features of the 2E-2v technique. Dedicated simulations were also performed using the GEF code to study important aspects of the 2E-2v technique. Our simulations show that prompt neutron emission has a non-negligible impact on the deduced fragment data and affects also the shape of 17(A). Geometrical constraints lead to a total-kinetic energy-dependent detection efficiency. The 2E technique utilizes an ionization chamber together with two liquid scintillator detectors. Two measurements have been performed, one of Cf-252(sf) and another one of thermal-neutron induced fission in U-235(n,f). Results from Cf-252(sf) are reported here.
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15.
  • Alrutz, Marie, et al. (författare)
  • Projektledning
  • 2013
  • Bok (populärvet., debatt m.m.)abstract
    • Projektledning är ett yrke med egen certifiering. Det pågår en spännande utveckling inom området och det blir allt viktigare att hålla sig ajour med utvecklingen.Det övergripande målet med den här handboken är att vara en ständigt aktuell heltäckande bok om projektar­bete. Innehållsmässigt täcker den både frågor som har med struktur och styrning att göra och frågor om ledning av människor och mänskliga processer i grupp. Kompetens inom projekt byggs av både kunskap och erfarenhet. Vi följer kontinuerligt aktuell forskning inom dessa områden och bjuder in intressanta forskare att medverka som författare. Vi skildrar verkliga projekt och låter erfarenheterna få plats, både de bästa erfarenheterna och de utmaningar som man tagit sig igenom.Handboken är levande och det innebär att artiklar tas bort för att ge plats för nya, i takt med att den uppdateras fortlöpande.
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16.
  • Alves, Gustavo R., et al. (författare)
  • International Cooperation for Remote Laboratory Use
  • 2018
  • Ingår i: Contributions to Higher Engineering Education. - Singapore : Springer. - 9789811089176 ; , s. 1-31
  • Bokkapitel (refereegranskat)abstract
    • Experimenting is fundamental to the training process of all scientists and engineers. While experiments have been traditionally done inside laboratories, the emergence of Information and Communication Technologies added two alternatives accessible anytime, anywhere. These two alternatives are known as virtual and remote laboratories and are sometimes indistinguishably referred as online laboratories. Similarly to other instructional technologies, virtual and remote laboratories require some effort from teachers in integrating them into curricula, taking into consideration several factors that affect their adoption (i.e., cost) and their educational effectiveness (i.e., benefit). This chapter analyzes these two dimensions and sustains the case where only through international cooperation it is possible to serve the large number of teachers and students involved in engineering education. It presents an example in the area of electrical and electronics engineering, based on a remote laboratory named Virtual Instruments System in Reality, and it then describes how a number of European and Latin American institutions have been cooperating under the scope of an Erasmus+ project, for spreading its use in Brazil and Argentina.
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17.
  • Bergh, Andreas (författare)
  • Vad gör kvalitet med utbildning? : Om kvalitetsbegreppets skilda innebörder och dess konsekvenser för utbildning
  • 2010
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The aim of this dissertation is to investigate what linguistic meanings the concept of quality is imbued with in different educational arenas and to discuss the consequences of such meanings for education. From this aim the main research question is: What does the concept of quality do to education and what does education do to the concept of quality? The question indicates an interest in understanding how the concept of quality and education mutually influence each other. The empirical material consists of national texts written by the government and the national school authorities, mainly between the years of 1997 to 2008, as well as interviews with different people from three local school authorities and schools. Theoretically the approach is inspired by Quentin Skinner and speech-act theory as well as Reinhart  Koselleck and conceptual history. While Skinner is mainly interested in the rhetorical use of concepts, Koselleck’s interest lies in investigating how concepts carry historical time. For this study, some analytical concepts are lifted from these two theories and are applied to the empirical material. From the analysis, four concluding criteria of application are formulated: education quality, result quality, market quality and system quality. The result shows that certain meanings, which for a long time have been connected to education and, in this study, are incorporated under the umbrella criterion education quality, have been challenged and partly  marginalized. Instead, the dominance of result quality, market quality and system quality lead to an acceptance of new social perceptions in education. The different national and local structures that are developed to measure quality have a high impact on local practice. As a consequence of a shift from goal to result, overriding goals are clarified and made juridically controllable. The changes also lead to consequences for the different actors in the education system, as well as for teachers, national politicians and for national and local school administrations.
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18.
  • Bergman, Bo, 1943, et al. (författare)
  • An Emerging Science of Improvement in Health Care
  • 2015
  • Ingår i: Quality Engineering. - : Informa UK Limited. - 1532-4222 .- 0898-2112. ; 27:1, s. 17-34
  • Tidskriftsartikel (refereegranskat)abstract
    • ABSTRACT The purpose of this article is to describe the emerging science of improvement in health care and to add a perspective from the industrial quality improvement movement, the use of data from quality registers, and to give some personal reflections and suggestions. Furthermore, we want to introduce to the broader quality management community what is happening in healthcare with respect to quality improvement. We will discuss some of the challenges of the health care system and the current status of a science ofimprovement and give some suggestions for further improvements to the area.We discuss a possible extension of improvement knowledge and thetheoretical and practical arsenal of a science of improvement, in particular, understanding variation and implications for the use of, for, example controlcharts. In addition, the normative side of a science of improvement is discussed. The article ends with some brief reflections of use for future research agendas.
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19.
  • Bergman, Bo, 1943, et al. (författare)
  • Rejoinder
  • 2015
  • Ingår i: Quality Engineering. - : Informa UK Limited. - 1532-4222 .- 0898-2112. ; 27:1, s. 41-43
  • Tidskriftsartikel (refereegranskat)abstract
    • The authors agree that operations management is a discipline of great importance to a science of improvement in health care. They also believe that action research (AR) aiming for sustainable system changes and also providing a more beneficial context for process improvements is an important and fruitful way forward. AR is an approach to inquiry where the researcher(s) engage in collaborative communities with practitioners on an equal grounding. The role of the patient as a co-producer illuminates the importance of person-centered care, where patients and health care professionals collaborate on stated care plans. When the patient is included in the care plan as an equal partner there can be room for increased self-management and empowered patients contributing to safe care. In conclusion, the authors agree with Does and colleagues about the importance of operations management and its different practices.
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21.
  • Brännström, Andreas, et al. (författare)
  • Intermittent thoracic resuscitative endovascular balloon occlusion of the aorta improves renal function compared to 60 min continuous application after porcine class III hemorrhage
  • 2023
  • Ingår i: European Journal of Trauma and Emergency Surgery. - : Springer Berlin/Heidelberg. - 1863-9933 .- 1863-9941. ; 49:3, s. 1303-1313
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) may be considered for stabilization of patients with hemorrhage from below the diaphragm. Occluding the aorta is a powerful means of hemorrhagic control but is also associated with acute kidney injury, which increases mortality in trauma patients. Allowing for intermittent distal blood flow during REBOA application (iREBOA) could decrease this risk, but circulatory consequences have not been sufficiently elucidated. Therefore, we investigated circulatory effects and the renal artery blood flow (RBF) in iREBOA versus continuous, complete aortic occlusion (cREBOA).Methods In a porcine model of uncontrolled class III hemorrhage (34% estimated total blood volume, mean 1360 mL), swine (n = 12, mean weight 60.3 kg) were randomly assigned to iREBOA: 3-min full deflation every 10 min (n = 6), or cREBOA (n = 6), for 60 min of thoracic (zone I) application. The animals then underwent 60 min of reperfusion (critical care phase). Results Survival was 100% in iREBOA and 83% in cREBOA. The intermittent balloon deflation protocol was hemodynamically tolerable in 63% of reperfusion intervals. Systolic blood pressure decreased during the reperfusion intervals in iREBOA animals (mean 108 mm Hg versus 169 mm Hg; p < 0.005). No differences were detected in heart rate, cardiac output or stroke volume between methods. Troponin I increased in cREBOA after 60 min (mean 666-187 ng/L, p < 0.05). The norepinephrine requirement increased in cREBOA during reperfusion (mean infusion time 12.5-5.5 min; p < 0.05). Total ischemic time decreased in iREBOA (60.0-48.6 min; p < 0.001). RBF increased in iREBOA during balloon deflations and after 60 min reperfusion (61%-39% of baseline RBF; p < 0.05). Urine output increased in iREBOA (mean 135-17 mL; p < 0.001). Nephronal osteopontin, a marker of ischemic injury, increased in cREBOA (p < 0.05).Conclusion iREBOA was survivable, did not cause rebleeding, decreased the total ischemic time and increased the renal blood flow, urine output and decreased renal ischemic injury compared to cREBOA. Intermittent reperfusions during REBOA may be preferred to be continuous, complete occlusion in prolonged application to improve renal function.
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23.
  • Chen, Hui, 1992, et al. (författare)
  • MCRB-based Performance Analysis of 6G Localization under Hardware Impairments
  • 2022
  • Ingår i: 2022 IEEE International Conference on Communications Workshops, ICC Workshops 2022. ; , s. 115-120
  • Konferensbidrag (refereegranskat)abstract
    • Location information is expected to be the key to meeting the needs of communication and context-aware services in 6G systems. User localization is achieved based on delay and/or angle estimation using uplink or downlink pilot signals. However, hardware impairments (HWIs) distort the signals at both the transmitter and receiver sides and thus affect the localization performance. While this impact can be ignored at lower frequencies where HWIs are less severe, modeling and analysis efforts are needed for 6G to evaluate the localization degradation due to HWIs. In this work, we model various types of impairments and conduct a misspecified Cramér-Rao bound analysis to evaluate the HWI-induced performance loss. Simulation results with different types of HWIs show that each HWI leads to a different level of degradation in angle and delay estimation performance.
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24.
  • Christenson, Andreas, et al. (författare)
  • Direct and mediated electron transfer between intact succinate:quinone oxidoreductase from Bacillus subtilis and a surface modified gold electrode reveals redox state-dependent conformational changes.
  • 2008
  • Ingår i: Biochimica et Biophysica Acta - Bioenergetics. - : Elsevier BV. - 0005-2728. ; 1777:9, s. 1203-1210
  • Tidskriftsartikel (refereegranskat)abstract
    • Succinate:quinone oxidoreductase (SQR) from Bacillus subtilis consists of two hydrophilic protein subunits comprising succinate dehydrogenase, and a di-heme membrane anchor protein harboring two putative quinone binding sites, Q(p) and Q(d). In this work we have used spectroelectrochemistry to study the electronic communication between purified SQR and a surface modified gold capillary electrode. In the presence of two soluble quinone mediators the midpoint potentials of both hemes were revealed essentially as previously determined by conventional redox titration (heme b(H), E(m)=+65 mV, heme b(L), E(m)=-95 mV). In the absence of mediators the enzyme still communicated with the electrode, albeit with a reproducible hysteresis, resulting in the reduction of both hemes occurring approximately at the midpoint potential of heme b(L), and with a pronounced delay of reoxidation. When the specific inhibitor 2-n-heptyl-4 hydroxyquinoline N-oxide (HQNO), which binds to Q(d) in B. subtilis SQR, was added together with the two quinone mediators, rapid reductive titration was still possible which can be envisioned as an electron transfer occurring via the HQNO insensitive Q(p) site. In contrast, the subsequent oxidative titration was severely hampered in the presence of HQNO, in fact it completely resembled the unmediated reaction. If mediators communicate with Q(p) or Q(d), either event is followed by very rapid electron redistribution within the enzyme. Taken together, this strongly suggests that the accessibility of Q(p) depended on the redox state of the hemes. When both hemes were reduced, and Q(d) was blocked by HQNO, quinone-mediated communication via the Q(p) site was no longer possible, revealing a redox-dependent conformational change in the membrane anchor domain.
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25.
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26.
  • Czarniawska, Barbara, 1948, et al. (författare)
  • Organisering kring hot och risk
  • 2007
  • Bok (övrigt vetenskapligt/konstnärligt)abstract
    • Hur hanteras blödarfeberviruset Marburg, hur förbereder man sig för ett eventuellt utbrott av fågelinfluensan, hur kalkylerar man hälsorisker i Europa och Sverige och hur hanterar man risk i samband med äventyrsturism? Vad har stormen Gudrun lärt oss om att hantera akuta situationer och hur skapar katastrofer som Tjörnbron handlingsföreträde i form av särskilda förutsättningar för organisering? Detta är några exempel på studier inkluderade i Organisering kring hot och risk. Boken tittar även närmare på hur man hanterar effekter av datorkriser, hur konst och vad betraktaren bedömer som hot kan bidra till skapande av handlingsnät samt hur tv-serien Kommissionen belyser det svenska beredningsarbetet. Författarna visar att karaktären av organisering kring hot och risk är beroende av tidpunkten: innan, under eller efter en katastrof eller en hotfull händelse. Beredningsarbetet består av resursmobilisering, att skissa planer, att bygga upp strukturer samt bygga eller mobilisera nätverk. När katastrofen väl inträffar visar det sig dock att även de bästa planer inte alltid fungerar som man vill och responsen på de faktiska händelserna består av improvisation samt av att bygga handlingskedjor och handlingsnät. Det finns inget recept på hur man skall organisera kring hot och risk men boken har identifierat ett återkommande problem: varje misslyckande verkar leda till slutsatsen att det behövs mer av planer och strukturer. Författarna hävdar motsatsen. Bokens budskap är att istället för att skapa oändliga planer och strukturer skall man öva lämpliga skickligheter och improvisationsförmåga. Boken vänder sig till studerande inom organisationsteori respektive riskhantering på universitet och högskola samt yrkesverksamma inom krisberedskap och riskhantering.
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27.
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28.
  • Dam-Larsen, Sanne, et al. (författare)
  • Best practice in placement of percutaneous endoscopic gastrostomy with jejunal extension tube for continuous infusion of levodopa carbidopa intestinal gel in the treatment of selected patients with Parkinsons disease in the Nordic region
  • 2015
  • Ingår i: Scandinavian Journal of Gastroenterology. - : TAYLOR and FRANCIS LTD. - 0036-5521 .- 1502-7708. ; 50:12, s. 1500-1507
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective. Continuous infusion of levodopa carbidopa intestinal gel (LCIG) is associated with a significant improvement in the symptoms and quality of life of selected patients with advanced Parkinsons disease. Percutaneous endoscopic gastrostomy with jejunal extension (PEG/J) was first described in 1998 and has become the most common and standard technique for fixing the tubing in place for LCIG infusion. Material and methods. A workshop was held in Stockholm, Sweden, to discuss the PEG/J placement for the delivery of LCIG in Parkinsons disease patients with the primary goal of providing guidance on best practice for the Nordic countries. Results. Suggested procedures for preparation of patients for PEG/J placement, aftercare, troubleshooting and redo-procedures for use in the Nordic region are described and discussed. Conclusions. LCIG treatment administered through PEG/J-tubes gives a significant increase in quality of life for selected patients with advanced Parkinsons disease. Although minor complications are common, serious complications are infrequent, and the tube insertion procedures have a good safety record. Further development of delivery systems and evaluation of approaches designed to reduce the demand for redo endoscopy are required.
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29.
  • Ekeskär, Andreas, 1984-, et al. (författare)
  • Construction logistics in a multi-project context: coopetition among main contractors and the role of third-party logistics providers
  • 2022
  • Ingår i: Construction Management and Economics. - : Taylor & Francis. - 0144-6193 .- 1466-433X. ; 40:1, s. 25-40
  • Tidskriftsartikel (refereegranskat)abstract
    • As a part of supply chain management (SCM) initiatives to improve performance and productivity in construction projects, the use of construction logistics setups (CLSs) operated by third-party logistics (TPL) providers have increased. CLSs are often used in complex multi-project contexts, such as urban development districts, where extensive coordination of actors, resources, and activities is needed. The purpose of this paper is twofold: to investigate how main contractors engage in horizontal relationships with each other when coordinating activities and resources within and across projects in a multi-project context, and to investigate what role a TPL provider assumes when engaging in relationships with main contractors in a multi-project context. The findings are based on a case study of an urban development district with a mandatory TPL-operated CLS, and we apply the industrial network approach. In this multi-project context, the main contractors engage in coopetitive relationships, coordinating activities and resources within and across projects. The TPL provider coordinates actors, resources, and activities, facilitating smoother production by managing logistics and mediating coopetitive relationships. This can be understood as a multi-project coordination role and extends the role SCM can play in construction. In that role, a TPL provider can minimise tensions between coopetitive actors across a multitude of horizontal relationships and projects.
  •  
30.
  • Ekeskär, Andreas, 1984-, et al. (författare)
  • Horizontal Inter-Organizational Collaboration : The Case of Third-Party Logistics
  • 2019
  • Ingår i: Proceedings of the 35th Annual ARCOM Conference, 2-4 September 2019, Leeds, UK, Association of Researchers in Construction Management (ARCOM). ; , s. 821-830
  • Konferensbidrag (refereegranskat)abstract
    • As a measure to increase performance, improve safety and reduce environmental impact, the use of third-party logistics (TPL) solutions has increased in the construction industry. Other measures are inter-organizational collaborative methods and agreements between different actors. The purpose of this study is to explore how a TPL solution can affect inter-organizational relationships, specifically in the horizontal dimension. Findings are based on a case study of an urban development project with a TPL solution mandatory to use for all construction actors working side by side in parallel and sequential stages. The analysis is based on the industrial network approach, using the ARA-model for identifying and analyzing inter-organizational interactions among main contractors. The findings indicate that the contractors do collaborate with each other on both technical and organizational resources, as well as coordinate activities between each other, and that the TPL solution has a vital role in bringing them together and improves collaboration. This nuance the predominant view of the construction industry as being characterized by adversarial relationships and lack of inter-organizational collaboration. It also extends the knowledge of what a TPL solution can contribute with besides improved logistics.
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31.
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32.
  • Gad, Helge, et al. (författare)
  • MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
  • 2014
  • Ingår i: Nature. - : Nature Publishing Group. - 0028-0836 .- 1476-4687. ; 508:7495, s. 215-221
  • Tidskriftsartikel (refereegranskat)abstract
    • Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes oxidized dNTP pools to prevent incorporation of damaged bases during DNA replication. Although MTH1 is non-essential in normal cells, we show that cancer cells require MTH1 activity to avoid incorporation of oxidized dNTPs, resulting in DNA damage and cell death. We validate MTH1 as an anticancer target in vivo and describe small molecules TH287 and TH588 as first-in-class nudix hydrolase family inhibitors that potently and selectively engage and inhibit the MTH1 protein in cells. Protein co-crystal structures demonstrate that the inhibitors bindin the active site of MTH1. The inhibitors cause incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts. This study exemplifies the non-oncogene addiction concept for anticancer treatment and validates MTH1 as being cancer phenotypic lethal.
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33.
  • Galli, Raoul, et al. (författare)
  • En prosopografisk studie över konsthögskoleelever och konstnärer 1939-2005
  • 2008
  • Ingår i: Praktiske Grunde. - 1902-2271. ; :1, s. 18-45
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Den här artikeln ger några exempel på hur vi gått till väga för att samla in data om kollektiva konstnärsbanor. Vår ambition är att följa individerna från vaggan – via skolor – till konstfältet. I ett första huvudavsnitt koncentrerar vi oss på de elever som var inskrivna på Kungliga Konsthögskolan i Stockholm åren 1939 till 1986. Hur många förberedande konstutbildningar hade de gått innan de kom in på skolan? Hur många ansökningar lämnade de in innan de blev antagna? Var manliga elever mer framgångsrika än kvinnliga i att få stipendier och belöningar under skoltiden? Vad skiljer eleverna som utexaminerades under en period då konstfältet präglades av ”postmodernism” från eleverna som utexaminerades under en tidigare era märkt av ”efterkrigstidsmodernism”? I det andra huvudavsnittet lämnar vi skolans värld för att i stället koncentrera oss på verksamma – utexaminerade – konstnärer i det svenska konstfältet 1945-2005. Vi ställer delvis samma typ av frågor i denna del: var manliga konstnärer mer framgångsrika än kvinnliga i att få stipendier och belöningar efter skoltiden? Hur har stipendieutdelningen förändrats över tid? Avslutningsvis lyfter vi fram tidskrifter och kritiker som hade en central roll i hallstämplandet av svenska konstnärskap.
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34.
  • Godoy, Patricio, et al. (författare)
  • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
  • 2013
  • Ingår i: Archives of Toxicology. - : Springer Science and Business Media LLC. - 0340-5761 .- 1432-0738. ; 87:8, s. 1315-1530
  • Forskningsöversikt (refereegranskat)abstract
    • This review encompasses the most important advances in liver functions and hepatotoxicity and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested, zonated lobules, the liver consists of approximately 80 % hepatocytes and 20 % non-parenchymal cells, the latter being involved in a secondary phase that may dramatically aggravate the initial damage. Hepatotoxicity, as well as hepatic metabolism, is controlled by a set of nuclear receptors (including PXR, CAR, HNF-4 alpha, FXR, LXR, SHP, VDR and PPAR) and signaling pathways. When isolating liver cells, some pathways are activated, e.g., the RAS/MEK/ERK pathway, whereas others are silenced (e.g. HNF-4 alpha), resulting in up- and downregulation of hundreds of genes. An understanding of these changes is crucial for a correct interpretation of in vitro data. The possibilities and limitations of the most useful liver in vitro systems are summarized, including three-dimensional culture techniques, co-cultures with non-parenchymal cells, hepatospheres, precision cut liver slices and the isolated perfused liver. Also discussed is how closely hepatoma, stem cell and iPS cell-derived hepatocyte-like-cells resemble real hepatocytes. Finally, a summary is given of the state of the art of liver in vitro and mathematical modeling systems that are currently used in the pharmaceutical industry with an emphasis on drug metabolism, prediction of clearance, drug interaction, transporter studies and hepatotoxicity. One key message is that despite our enthusiasm for in vitro systems, we must never lose sight of the in vivo situation. Although hepatocytes have been isolated for decades, the hunt for relevant alternative systems has only just begun.
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35.
  • Gustafsson, Anders, 1985- (författare)
  • Industrial policy : Political considerations, payoffs, and peculiar incentives
  • 2018
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • This thesis consists of four independent papers. They deal with some aspects of industrial policy, namely public supports to firms that are intended to support innovation and growth at the firm level, using Swedish data. Two papers study the efficiency of current Swedish policies by estimating the effects of subsidies and public loans to firms, respectively.The results on subsidized firms suggests that there are some positive effects on profits and productivity, but these diminish and disappear over time. The results of public loans are more positive with long lasting effects on productivity and sales but only for smaller firms. Public loans do not lead to an increase in the number of employees in the firms that receive them.The third paper studies the selection of firms for subsidies and the incentives firms have to seek them. By modeling the decision to seek subsidies as a trade off between producing in the market and seeking grants, the results suggest that firms with low market productivity might self-select into seeking grants. The empirical results are in line with the theoretical predictions.The final paper studies the incentives that politicians have to implement programs and policies that they know will be inefficient. Since a lack of political action can make the politicians look incompetent, incumbentens have incentives to implement policies even though they know that these will be ineffective, to signal competence towards the voters.
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36.
  • Gustavsson, Andreas, 1974 (författare)
  • A reparametrization invariant surface ordering
  • 2005
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :11, s. 035 (artno)-
  • Tidskriftsartikel (refereegranskat)abstract
    • We introduce a notion of a non-abelian loop gauge field defined on points in loop space. For this purpose we first find an infinite-dimensional tensor product representation of the Lie algebra which is particularly suited for fields on loop space. We define the non-abelian Wilson surface as a 'time' ordered exponential in terms of this loop gauge field and show that it is reparametrization invariant.
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37.
  • Gustavsson, Andreas, 1982- (författare)
  • An Efficient Approach for Detecting Moving Objects and Deriving Their Positions and Velocities
  • 2020
  • Ingår i: Advances in Intelligent Systems and Computing. - Cham : Springer International Publishing. ; , s. 293-313
  • Konferensbidrag (refereegranskat)abstract
    • Well-functioning autonomous robot solutions heavily rely on the availability of fast and correct navigation solutions. The presence of dynamic/moving objects in the environment poses a challenge because the risk of collision increases. In order to derive the best and most foreseeing re-routing solutions for cases where the planned route suddenly involves the risk of colliding with a moving object, the robot's navigation system must be provided with information about such objects' positions and velocities. Based on sensor readings providing either 2-dimensional polar range scan or 3-dimensional point cloud data streams, we present an efficient and effective method which detects objects in the environment and derives their positions and velocities. The method has been implemented, based on the Robot Operating System (ROS), and we also present an evaluation of it. It was found that the method results in good accuracy in the position and velocity calculations, a small memory footprint and low CPU usage requirements.
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38.
  • Gustavsson, Anders, et al. (författare)
  • Corrigendum to “Cost of disorders of the brain in Europe 2010” [Eur. Neuropsychopharmacol. 21 (2011) 718–779]
  • 2012
  • Ingår i: European Neuropsychopharmacology. - : Elsevier BV. - 0924-977X .- 1873-7862. ; 22:3, s. 237-238
  • Tidskriftsartikel (refereegranskat)abstract
    • The spectrum of disorders of the brain is large, covering hundreds of disorders that are listed in either the mental or neurological disorder chapters of the established international diagnostic classification systems. These disorders have a high prevalence as well as short- and long-term impairments and disabilities. Therefore they are an emotional, financial and social burden to the patients, their families and their social network. In a 2005 landmark study, we estimated for the first time the annual cost of 12 major groups of disorders of the brain in Europe and gave a conservative estimate of €386 billion for the year 2004. This estimate was limited in scope and conservative due to the lack of sufficiently comprehensive epidemiological and/or economic data on several important diagnostic groups. We are now in a position to substantially improve and revise the 2004 estimates. In the present report we cover 19 major groups of disorders, 7 more than previously, of an increased range of age groups and more cost items. We therefore present much improved cost estimates. Our revised estimates also now include the new EU member states, and hence a population of 514 million people.
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39.
  • Gustavsson, Anders, et al. (författare)
  • Cost of disorders of the brain in Europe 2010.
  • 2011
  • Ingår i: European Neuropsychopharmacology. - Amsterdam : Elsevier BV. - 0924-977X .- 1873-7862. ; 21:10, s. 718-79
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The spectrum of disorders of the brain is large, covering hundreds of disorders that are listed in either the mental or neurological disorder chapters of the established international diagnostic classification systems. These disorders have a high prevalence as well as short- and long-term impairments and disabilities. Therefore they are an emotional, financial and social burden to the patients, their families and their social network. In a 2005 landmark study, we estimated for the first time the annual cost of 12 major groups of disorders of the brain in Europe and gave a conservative estimate of €386 billion for the year 2004. This estimate was limited in scope and conservative due to the lack of sufficiently comprehensive epidemiological and/or economic data on several important diagnostic groups. We are now in a position to substantially improve and revise the 2004 estimates. In the present report we cover 19 major groups of disorders, 7 more than previously, of an increased range of age groups and more cost items. We therefore present much improved cost estimates. Our revised estimates also now include the new EU member states, and hence a population of 514 million people.AIMS: To estimate the number of persons with defined disorders of the brain in Europe in 2010, the total cost per person related to each disease in terms of direct and indirect costs, and an estimate of the total cost per disorder and country.METHODS: The best available estimates of the prevalence and cost per person for 19 groups of disorders of the brain (covering well over 100 specific disorders) were identified via a systematic review of the published literature. Together with the twelve disorders included in 2004, the following range of mental and neurologic groups of disorders is covered: addictive disorders, affective disorders, anxiety disorders, brain tumor, childhood and adolescent disorders (developmental disorders), dementia, eating disorders, epilepsy, mental retardation, migraine, multiple sclerosis, neuromuscular disorders, Parkinson's disease, personality disorders, psychotic disorders, sleep disorders, somatoform disorders, stroke, and traumatic brain injury. Epidemiologic panels were charged to complete the literature review for each disorder in order to estimate the 12-month prevalence, and health economic panels were charged to estimate best cost-estimates. A cost model was developed to combine the epidemiologic and economic data and estimate the total cost of each disorder in each of 30 European countries (EU27+Iceland, Norway and Switzerland). The cost model was populated with national statistics from Eurostat to adjust all costs to 2010 values, converting all local currencies to Euro, imputing costs for countries where no data were available, and aggregating country estimates to purchasing power parity adjusted estimates for the total cost of disorders of the brain in Europe 2010.RESULTS: The total cost of disorders of the brain was estimated at €798 billion in 2010. Direct costs constitute the majority of costs (37% direct healthcare costs and 23% direct non-medical costs) whereas the remaining 40% were indirect costs associated with patients' production losses. On average, the estimated cost per person with a disorder of the brain in Europe ranged between €285 for headache and €30,000 for neuromuscular disorders. The European per capita cost of disorders of the brain was €1550 on average but varied by country. The cost (in billion €PPP 2010) of the disorders of the brain included in this study was as follows: addiction: €65.7; anxiety disorders: €74.4; brain tumor: €5.2; child/adolescent disorders: €21.3; dementia: €105.2; eating disorders: €0.8; epilepsy: €13.8; headache: €43.5; mental retardation: €43.3; mood disorders: €113.4; multiple sclerosis: €14.6; neuromuscular disorders: €7.7; Parkinson's disease: €13.9; personality disorders: €27.3; psychotic disorders: €93.9; sleep disorders: €35.4; somatoform disorder: €21.2; stroke: €64.1; traumatic brain injury: €33.0. It should be noted that the revised estimate of those disorders included in the previous 2004 report constituted €477 billion, by and large confirming our previous study results after considering the inflation and population increase since 2004. Further, our results were consistent with administrative data on the health care expenditure in Europe, and comparable to previous studies on the cost of specific disorders in Europe. Our estimates were lower than comparable estimates from the US.DISCUSSION: This study was based on the best currently available data in Europe and our model enabled extrapolation to countries where no data could be found. Still, the scarcity of data is an important source of uncertainty in our estimates and may imply over- or underestimations in some disorders and countries. Even though this review included many disorders, diagnoses, age groups and cost items that were omitted in 2004, there are still remaining disorders that could not be included due to limitations in the available data. We therefore consider our estimate of the total cost of the disorders of the brain in Europe to be conservative. In terms of the health economic burden outlined in this report, disorders of the brain likely constitute the number one economic challenge for European health care, now and in the future. Data presented in this report should be considered by all stakeholder groups, including policy makers, industry and patient advocacy groups, to reconsider the current science, research and public health agenda and define a coordinated plan of action of various levels to address the associated challenges.RECOMMENDATIONS: Political action is required in light of the present high cost of disorders of the brain. Funding of brain research must be increased; care for patients with brain disorders as well as teaching at medical schools and other health related educations must be quantitatively and qualitatively improved, including psychological treatments. The current move of the pharmaceutical industry away from brain related indications must be halted and reversed. Continued research into the cost of the many disorders not included in the present study is warranted. It is essential that not only the EU but also the national governments forcefully support these initiatives.
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40.
  • Gustavsson, Andreas, 1974 (författare)
  • Dynamics of a wavy plane Wilson surface observable from AdS-CFT correspondence
  • 2005
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2005:1, s. 022 (artno)-
  • Tidskriftsartikel (refereegranskat)abstract
    • Guided by the paper [10] by Polyakov and Rychkov, we compute the second variational derivative of a wavy plane Wilson surface observable, to find a necessary condition for a proposed surface equation to be satisfied in the large-N limit is that we are in the critical dimension D = 6.
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41.
  • Gustavsson, Andreas, 1974 (författare)
  • Electric-Magnetic Duality and Supersymmetry in Four and Six Dimensions
  • 2002
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • We study some aspects of the still very mysterious M-theory five-brane, mostly from the world-sheet field theory perspective. One aspect is the Seiberg-Witten curve in N = 2 four-dimensional super Yang-Mills theory. We also consider the six-dimensional theories which have an A-D-E classification where the AN - 1 theories should correspond to the world-sheet theories on a stack of N parallel M five-branes. We will not have much to say about this very difficult problem. But already a single M five-brane presents some problems, and so we will also review this.
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42.
  • Gustavsson, Andreas, 1974 (författare)
  • Energy radiated from a fluctuating selfdual string
  • 2005
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :8, s. 043 (artno)-
  • Tidskriftsartikel (refereegranskat)abstract
    • We compute the energy that is radiated from a fluctuating selfdual string in the large-N limit of AN-1 theory using the AdS-CFT correspondence. We find that the radiated energy is given by a non-local expression integrated over the string world-sheet. We also make the corresponding computation for a charged string in six-dimensional classical electrodynamics, thereby generalizing the Larmor formula for the radiated energy from an accelerated point particle.
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43.
  • Gustavsson, Andreas, et al. (författare)
  • Formalizing the Intent of Design Patterns. An Approach Towards a Solution to the Indexing Problem
  • 1999
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • The intent section of a pattern description is written in easily understood, natural language, which unfortunately has the drawback of being too imprecise and unstructured for certain applications of the intent section.We will in this essay try to formalize the intent section of a pattern description. Our aim will be to find a structure within the intent description that will reduce ambiguities and at the same time make the classification of patterns easier. The classifications of patterns addresses the problem of "labeling" patterns into one of the following categories: Creational, Structural or Behavioural. Succeeding in classifying patterns by the intent does require that enough information for doing so is contained in the one to two sentences that make up the intent. Whether this is the case or not will be discussed in the essay.A formalized intent section of a pattern description can not replace the understandability of the natural language description but can be thought of as a complement to the standard structure to patterns today.
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44.
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45.
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46.
  • Gustavsson, Andreas (författare)
  • Superconformal indices on S1×(S5/Ζp)
  • 2019
  • Ingår i: Nuclear Physics B. - : Elsevier BV. - 0550-3213 .- 1873-1562. ; 945
  • Tidskriftsartikel (refereegranskat)abstract
    • We obtain generating functions associated to the abelian superconformal indices for 6d (1,0) tensor and hypermultiplets on S1×(S5/Zp). We extract the superconformal indices and their high and low temperature behaviors. We consider round and generically squashed S5 in turn. We show that the unsquashed limit of the superconformal indices is smooth. We examine S-duality in the large p limit that acts by exchanging the Hopf circle with the temporal circle.
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47.
  • Gustavsson, Andreas (författare)
  • The non-Abelian tensor multiplet
  • 2018
  • Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; :7
  • Tidskriftsartikel (refereegranskat)abstract
    • We assume the existence of a background vector field that enables us to make an ansatz for the superconformal transformations for the non-Abelian 6d (1, 0) tensor multiplet. Closure of supersymmetry on generators of the conformal algebra and the R-symmetry, requires that the vector field is Abelian, has scaling dimension minus one and that the supersymmetry parameter as well as all the fields in the tensor multiplet have vanishing Lie derivatives along this vector field. We couple the tensor multiplet to an ad-joint hypermultiplet, and present a Lagrangian for the combined system that has enhanced (2, 0) superconformal symmetry. We also obtain the off-shell supersymmetry variations for both the tensor and the hypermultiplets.
  •  
48.
  • Gustavsson, Andreas, 1982-, et al. (författare)
  • Timing Analysis of Parallel Software Using Abstract Execution
  • 2014
  • Ingår i: VERIFICATION, MODEL CHECKING, AND ABSTRACT INTERPRETATION. - Berlin, Heidelberg : SPRINGER-VERLAG BERLIN. - 9783642540134 ; , s. 59-77, s. 59-77
  • Konferensbidrag (refereegranskat)abstract
    • A major trend in computer architecture is multi-core processors. To fully exploit this type of parallel processor chip, programs running on it will have to be parallel as well. This means that even hard real-time embedded systems will be parallel. Therefore, it is of utmost importance that methods to analyze the timing properties of parallel real-time systems are developed. This paper presents an algorithm that is founded on abstract interpretation and derives safe approximations of the execution times of parallel programs. The algorithm is formulated and proven correct for a simple parallel language with parallel threads, shared memory and synchronization via locks.
  •  
49.
  • Gustavsson, Andreas, et al. (författare)
  • Toward Static Timing Analysis of Parallel Software
  • 2012
  • Ingår i: Proc. 12th International Workshop on Worst-Case Execution-Time Analysis (WCET'12). - 9783939897415 ; , s. 38-47
  • Konferensbidrag (refereegranskat)abstract
    • The current trend within computer, and even real-time, systems is to incorporate parallel hardware, e.g., multicore processors, and parallel software. Thus, the ability to safely analyse such parallel systems, e.g., regarding the timing behaviour, becomes necessary. Static timing analysis is an approach to mathematically derive safe bounds on the execution time of a program, when executed on a given hardware platform. This paper presents an algorithm that statically analyses the timing of parallel software, with threads communicating through shared memory, using abstract interpretation. It also gives an extensive example to clarify how the algorithm works.
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50.
  • Gustavsson, Andreas (författare)
  • Worst-Case Execution Time Analysis of Parallel Systems
  • 2011
  • Ingår i: Real Time in Sweden 2011 (RTiS2011). ; , s. 104-107
  • Konferensbidrag (refereegranskat)abstract
    • The problem of finding the Worst-Case Execution Time, WCET, of a program executed on a specific hardware architecture is a very challenging task. A lot of effort has been put into analysing sequential programs executing on single-core hardware. The result is a variety of different methods and tools. The author currently works on finding methods for static WCET analysis of parallel software. The emphasis of the work is put on analysing the impact of synchronisation between threads executing on a shared memory architecture. The analysis is done on the software level, so less focus is put on the effects of the actual hardware on which the parallel program executes. The analysis is based on a small parallel programming language incorporating some fundamental synchronisation primitives; locking and unlocking of shared resources. The programming language is formally defined, which allows the correctness of the analysis to be proven.
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