| 1. |
- Wannberg, Gudmund, et al.
(författare)
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EISCAT_3D - a next-generation European radar system for upper atmosphere and geospace research
- 2010
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Ingår i: Radio Science Bulletin. - 1024-4530. ; :333, s. 75-88
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Tidskriftsartikel (refereegranskat)abstract
- The EISCAT Scientifi c Association, together with a number of collaborating institutions, has recently completed a feasibility and design study for an enhanced performance research radar facility to replace the existing EISCAT UHF and VHF systems. This study was supported by EU Sixth-Framework funding. The new radar retains the powerful multi-static geometry of the EISCAT UHF, but will employ phased arrays, direct-sampling receivers, and digital beamforming and beam steering. Design goals include, inter alia, a tenfold improvement in temporal and spatial resolution, an extension of the instantaneous measurement of full-vector ionospheric drift velocities from a single point to the entire altitude range of the radar, and an imaging capability to resolve small-scale structures. Prototype receivers and beamformers are currently being tested on a 48-element, 224 MHz array (the "Demonstrator") erected at the Kiruna EISCAT site, using the EISCAT VHF transmitter as an illuminator.
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| 2. |
- Dalin, P., et al.
(författare)
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Studies of noctilucent clouds from the stratosphere during the SONC balloon-borne experiment in 2021
- 2022
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Ingår i: Journal of Atmospheric and Solar-Terrestrial Physics. - : Elsevier BV. - 1364-6826 .- 1879-1824. ; 240
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Tidskriftsartikel (refereegranskat)abstract
- On the night 16–17 August 2021, a balloon-borne experiment called Stratospheric Observations of Noctilucent Clouds (SONC) was successfully performed. A big scientific balloon, having onboard three automated cameras for studies of noctilucent clouds (NLC), was launched to 32.7 km altitude from Esrange (northern Sweden). All three NLC cameras and electronics were completely operational in the stratosphere for more than 10 h at low temperatures of about −30 °C. Two wide angle cameras registered an extended NLC field of about 1700 km long in the twilight sky sector from the north-west to the north-east of Esrange. NLC were of a moderate brightness and were located at high latitudes between 68° and 71°N. The NLC field was located in a cold area (138–142 K) below the frost point temperature (145–148 K) in the mesopause region that was confirmed by Aura/MLS satellite and Esrange lidar measurements. The balloon-borne NLC measurements were accompanied by ground-based lidar and radar measurements. The latter have registered Polar Mesosphere Summer Echoes (PMSE) in the same volume of the summer mesopause along with NLC observed from the stratosphere that has been performed for the first time above northern Scandinavia. We describe the technique and method of the NLC observation from the stratosphere as well as present the first scientific results of the SONC experiment.
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| 3. |
- KC, Ashish, 1982-, et al.
(författare)
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Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries.
- 2023
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Ingår i: Nature human behaviour. - : Springer Science and Business Media LLC. - 2397-3374. ; 7:4, s. 529-544
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Tidskriftsartikel (refereegranskat)abstract
- Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from -90% to +30%, were reported in many countries following early COVID-19 pandemic response measures ('lockdowns'). It is unclear whether this variation reflects real differences in lockdown impacts, or perhaps differences in stillbirth rates and/or study designs. Here we present interrupted time series and meta-analyses using harmonized data from 52 million births in 26 countries, 18 of which had representative population-based data, with overall PTB rates ranging from 6% to 12% and stillbirth ranging from 2.5 to 10.5 per 1,000 births. We show small reductions in PTB in the first (odds ratio 0.96, 95% confidence interval 0.95-0.98, P value <0.0001), second (0.96, 0.92-0.99, 0.03) and third (0.97, 0.94-1.00, 0.09) months of lockdown, but not in the fourth month of lockdown (0.99, 0.96-1.01, 0.34), although there were some between-country differences after the first month. For high-income countries in this study, we did not observe an association between lockdown and stillbirths in the second (1.00, 0.88-1.14, 0.98), third (0.99, 0.88-1.12, 0.89) and fourth (1.01, 0.87-1.18, 0.86) months of lockdown, although we have imprecise estimates due to stillbirths being a relatively rare event. We did, however, find evidence of increased risk of stillbirth in the first month of lockdown in high-income countries (1.14, 1.02-1.29, 0.02) and, in Brazil, we found evidence for an association between lockdown and stillbirth in the second (1.09, 1.03-1.15, 0.002), third (1.10, 1.03-1.17, 0.003) and fourth (1.12, 1.05-1.19, <0.001) months of lockdown. With an estimated 14.8 million PTB annually worldwide, the modest reductions observed during early pandemic lockdowns translate into large numbers of PTB averted globally and warrant further research into causal pathways.
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| 4. |
- Mann, I., et al.
(författare)
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First wind shear observation in PMSE with the tristatic EISCAT VHF radar
- 2016
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Ingår i: Journal of Geophysical Research - Space Physics. - : Blackwell Publishing Ltd. - 2169-9380 .- 2169-9402. ; 121:11, s. 11,271-11,281
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Tidskriftsartikel (refereegranskat)abstract
- The Polar Summer Mesosphere has the lowest temperatures that occur in the entire Earth system. Water ice particles below the optically observable size range participate there in the formation of strong radar echoes (Polar Mesospheric Summer Echoes, PMSE). To study PMSE we carried out observations with the European Incoherent Scatter (EISCAT) VHF and EISCAT UHF radar simultaneously from a site near Tromsø (69.58°N, 19.2272°E) and observed VHF backscattering also with the EISCAT receivers in Kiruna (67.86°N, 20.44°E) and Sodankylä (67.36°N, 26.63°E). This is one of the first tristatic measurements with EISCAT VHF, and we therefore describe the observations and geometry in detail. We present observations made on 26 June 2013 from 7:00 to 13:00 h UT where we found similar PMSE patterns with all three VHF receivers and found signs of wind shear in PMSE. The observations suggest that the PMSE contains sublayers that move in different directions horizontally, and this points to Kelvin-Helmholtz instability possibly playing a role in PMSE formation. We find no signs of PMSE in the UHF data. The electron densities that we derive from observed incoherent scatter at UHF are at PMSE altitudes close to the noise level but possibly indicate reduced electron densities directly above the PMSE.
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| 5. |
- Scelo, G, et al.
(författare)
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International cancer seminars : a focus on kidney cancer.
- 2016
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Ingår i: Annals of Oncology. - : Elsevier BV. - 0923-7534 .- 1569-8041. ; 27:8, s. 1382-5
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Tidskriftsartikel (refereegranskat)abstract
- Recent years have seen important advances in our understanding of the etiology, biology and genetics of kidney cancer. To summarize important achievements and identify prominent research questions that remain, a workshop was organized by IARC and the US NCI. A series of 'difficult questions' were formulated, which should be given future priority in the areas of population, genomic and clinical research.
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| 6. |
- Abs, Roger, et al.
(författare)
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Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis.
- 2006
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Ingår i: European Journal of Endocrinology. - : Oxford University Press (OUP). - 0804-4643 .- 1479-683X. ; 155:1, s. 79-90
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of the present study was to clarify the relationship between GH deficiency (GHD) andsome cardiovascular risk factors and to analyse the effect of GH replacement therapy in a large numberof patients over a prolonged period of time.Design: Data for analysis were retrieved from KIMS (Pfizer International Metabolic Database). Serumconcentrations of total cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein(LDL)-cholesterol and triglycerides were obtained from 2589 patients at baseline and from 1206patients after 1 and 2 years of GH replacement therapy. Body mass index (BMI), waist and hip, restingblood pressure and body composition were also measured.Results: At baseline, the unfavourable effects of GHD were most obvious in the lipid profiledemonstrating elevated mean total and LDL-cholesterol, in the increased waist circumference and theelevated BMI. The cholesterol concentration, BMI and body composition were significantly adverselyaffected by a number of factors, including age, sex and the use of anti-epileptic drugs. The therapeuticeffect of GH was essentially uniform across the whole population. GH replacement reduced significantlythe mean total and LDL-cholesterol, the waist circumference and the fat mass and was maintainedduring 2 years.Conclusions: This analysis of a large number of patients confirmed that GHD adults present with anincreased cardiovascular risk. The sustained improvement of the adverse lipid profile and bodycomposition suggests that GH replacement therapy may reduce the risk of cardiovascular disease andthe premature mortality seen in hypopituitary patients with untreated GHD.
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| 7. |
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| 8. |
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| 9. |
- Andreeva, M. A., et al.
(författare)
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Polarization selection in Mössbauer reflectivity for magnetic multilayer investigation
- 2019
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Ingår i: VII Euro-Asian Symposium on Trends In Magnetism. - : IOP Publishing.
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Konferensbidrag (refereegranskat)abstract
- Mossbauer reflectivity experiment with polarization selection are reported. The use of the LiF polarization analyzer allows us to get the pi ->sigma' peak on the reflectivity curve at the critical angle and Mossbauer pi ->sigma' reflectivity spectra of reasonable quality at the critical angle and also at the Bragg angles of superlattice. The impressive difference of the reflectivity spectra measured near the critical angle with and without polarizations analysis is observed for [Fe-57(10)/V-10](20) multilayer characterizing by the ferromagnetic interlayer coupling. The combined fit of the whole set of spectra measured at different angles reveals the existence of antiferromagnetic Fe oxide phases in the top three bilayers. The experiment demonstrates benefits of the Mossbauer reflectivity with polarization analysis in ultrathin surface layer investigations.
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| 10. |
- Baulin, R. A., et al.
(författare)
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Unique surface sensitivity to ferro- and antiferromagnetic phases by polarization analysis in synchrotron Mossbauer reflectivity
- 2021
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Ingår i: SURFACES AND INTERFACES. - : Elsevier. - 2468-0230. ; 27
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Tidskriftsartikel (refereegranskat)abstract
- Polarization analysis of the reflected radiation has been performed in Mossbauer reflectivity measurements with a Synchrotron Mossbauer Source (SMS). Effective pi ->sigma' polarization selection is attained with LiF crystal ((6 2 2) 90 degrees-reflection for 14.4 keV radiation, angular acceptance similar to 100 '') capable of high pi ->pi' suppression. Basic features of the reflectivity with the rotated pi ->sigma' polarization are revealed in the experiment with the [Fe-57(10 ML)/V(20 ML)](20) multilayer. Selection of pi ->sigma' polarization component in Mossbauer reflectivity allows to exclude nonresonant electronic scattering, besides Mossbauer pi ->sigma' reflectivity spectra (R-spectra) contain only contributions from magnetized along the beam ferromagnetic phases. The antiferromagnetic iron oxides do not contribute to pi ->sigma' R-spectra (dichroic component is compensated). Therefore, in the Mossbauer reflectivity experiment supplemented by polarization analysis the data interpretation becomes more certain and gives information about depth position for ferromagnetic layers selectively. With this new technique we locate antiferromagnetic iron phases in the very top layer of [Fe-57(10 ML)/V(20 ML)](20) multilayer and ascertain the ferromagnetic ordered iron layers in the remaining part of the structure. This new approach in Mossbauer reflectivity has interesting perspectives for investigations of hyperfine interactions for iron complexes on the surface, ultrathin layers and multilayers with complicated magnetic structures.
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| 11. |
- Belova, E., et al.
(författare)
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The dynamical background of polar mesosphere winter echoes from simultaneous EISCAT and ESRAD observations
- 2005
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Ingår i: Annales Geophysicae. - : European Geosciences Union. - 0992-7689 .- 1432-0576. ; 23:4, s. 1239-1247
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Tidskriftsartikel (refereegranskat)abstract
- On 30 October 2004 during a strong solar proton event, layers of enhanced backscatter from altitudes between 55 and 75km have been observed by both ESRAD (52MHz) and the EISCAT VHF (224MHz) radars. These echoes have earlier been termed Polar Mesosphere Winter Echoes, PMWE. After considering the morphology of the layers and their relation to observed atmospheric waves, we conclude that the radars have likely seen the same phenomenon even though the radars' scattering volumes are located about 220km apart and that the most long-lasting layer is likely associated with wind-shear in an inertio-gravity wave. An ion-chemistry model is used to determine parameters necessary to relate wind-shear induced turbulent energy dissipation rates to radar backscatter. The model is verified by comparison with electron density profiles measured by the EISCAT VHF radar. Observed radar signal strengths are found to be 2-3 orders of magnitude stronger than the maximum which can be expected from neutral turbulence alone, assuming that previously published results relating radar signal scatter to turbulence parameters, and turbulence parameters to wind shear, are correct. The possibility remains that some additional or alternative mechanism may be involved in producing PMWE, such as layers of charged dust/smoke particles or large cluster ions.
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| 12. |
- Bilger, R, et al.
(författare)
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CELSIUS as an eta factory
- 1997
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Ingår i: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. - 0375-9474. ; 626:1-2, s. 93C-96C
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Tidskriftsartikel (refereegranskat)abstract
- The WASA project at the CELSIUS storage ring is being prepared for high-luminosity experiments to study rare decays of light mesons, in particular the eta meson. The CELSIUS ring together with the newly developed pellet target will serve as an efficient e
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| 13. |
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| 14. |
- Bilger, R, et al.
(författare)
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Two-pion production in proton-proton collisions near threshold at Celsius
- 1998
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Ingår i: ACTA PHYSICA POLONICA B. - : ACTA PHYSICA POLONICA B, JAGELLONIAN UNIV, INST PHYSICS. ; , s. 2987-2991
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Konferensbidrag (refereegranskat)abstract
- Two-pion production reactions in proton-proton collisions near threshold are measured using an internal cluster-jet hydrogen target and the WASA/PROMICE detector at the CELSIUS storage ring. Four out of the five possible two-pion production reactions are
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| 15. |
- Borneskog, Catrin, et al.
(författare)
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Changes in sexual behavior among high-school students over a 40-year period
- 2021
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Ingår i: Scientific Reports. - : Nature Research. - 2045-2322. ; 11:1
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to investigate sexual behavior, contraceptive use, risk factors as well as sources of sex information among first-year high-school students in Sweden. Secondly, to assess differences between genders and study programs as well as changes over a 40-year period. A repeated cross-sectional survey was conducted in two cities. A questionnaire comprising 77 items was used. The study population consisted of 415 students (63.4% females). The median age of sexual intercourse was 15 years. In total, 37% had had sexual intercourse, compared to 56.3% in 2009 and 45% in 1999 (p < 0.001), and the proportion of students who had their first sexual intercourse was not influenced by gender. More students in vocational programs (46.3%), compared to theoretical (33.3%), had experience of at least one sexual intercourse (p = 0.019). The same extend of contraception use at first and latest intercourse was reported, compared to previous studies. Forty-nine percent were mostly informed about sex from the internet, while in previous years, magazines, family and youth clinics were the main information sources. Comparing over time, students were in general less sexually experienced and less engaged in non-penetrative sex and physical intimacy. These findings call for a new approach, when designing sex and relationship education and health-care counseling in adolescents.
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| 16. |
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| 17. |
- Franck-Lissbrant, I, et al.
(författare)
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Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated adult rats.
- 1998
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Ingår i: Endocrinology. - : The Endocrine Society. - 0013-7227 .- 1945-7170. ; 139:2, s. 451-6
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Tidskriftsartikel (refereegranskat)abstract
- The castration-induced regression and testosterone stimulated regrowth of the vasculature in the rat ventral prostate lobe were studied using stereological techniques. Seven days after castration, the endothelial cell proliferation rate (bromodeoxyuridine labeling index); the total weights of blood vessel walls, blood vessel lumina, endothelial cells, glandular epithelial cells; and total organ weight were all decreased. Within 2 days after sc treatment with testosterone, the total weights of blood vessel walls, endothelial cells, and vascular lumina, as well as the endothelial cell proliferation rate, were all normalized. In contrast to the rapid response of the vasculature, the total weight of glandular epithelium and total organ weight were not normalized during the 4 days of testosterone treatment. Growth of the vasculature apparently precedes growth of the glandular epithelium. The testosterone- dependent factors stimulating the vasculature are unknown, but factors derived from epithelial cells, mast cells (which accumulate in the prostate during the first day of testosterone treatment), and tissue macrophages could all be involved. Castration-induced regression and testosterone-stimulated regrowth of the prostatic vasculature can be used as an experimental model to study factors regulating angiogenesis and organ growth in the prostate.
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| 18. |
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| 19. |
- Häggström, S, et al.
(författare)
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Testosterone induces vascular endothelial growth factor synthesis in the ventral prostate in castrated rats.
- 1999
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Ingår i: Journal of Urology. - 0022-5347 .- 1527-3792. ; 161:5, s. 1620-5
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: Recent studies suggest that the vasculature is important for the control of prostate growth. Castration induces an involution of the prostate gland and its vasculature. Replacement of testosterone stimulates endothelial cell proliferation and normalizes vascular volumes and blood flow several days before organ regrowth. Antiangiogenesis treatment inhibits the growth of prostate tumors. Understanding the regulation of the prostate vasculature may therefore provide important knowledge of the mechanisms responsible for the growth of non-malignant and malignant prostate tissue. Castration induced regression and testosterone stimulated regrowth of the prostatic vasculature have here been used to study the involvement of the angiogenic factor vascular endothelial growth factor (VEGF) and its receptors flt-1 and flk-1/KDR in the regulation of the prostatic vasculature.MATERIALS AND METHODS: VEGF, flt-1, and flk-1/KDR levels were quantified in the rat ventral prostate following castration and testosterone replacement. Methods used were competitive RT-PCR, Western blot and immunohistochemistry.RESULTS: VEGF mRNA and protein levels were significantly decreased by castration and testosterone treatment induced VEGF synthesis in the rat ventral prostate epithelium. Flt-1 and flk-1/KDR receptor levels were unaffected by castration and testosterone treatment.CONCLUSIONS: Castration down regulates VEGF and testosterone induces VEGF synthesis in epithelial cells in the rat ventral prostate.
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| 20. |
- Johansson, Mattias, et al.
(författare)
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The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study
- 2019
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Ingår i: PLoS Medicine. - : Public Library of Science (PLoS). - 1549-1277 .- 1549-1676. ; 16:1
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as proxies for putative risk factors and evaluated their relation to RCC risk in a mendelian randomization (MR) framework. This methodology limits bias due to confounding and is not affected by reverse causation.Methods and findings: Genetic markers associated with obesity measures, blood pressure, lipids, type 2 diabetes, insulin, and glucose were initially identified as instrumental variables, and their association with RCC risk was subsequently evaluated in a genome-wide association study (GWAS) of 10,784 RCC patients and 20,406 control participants in a 2-sample MR framework. The effect on RCC risk was estimated by calculating odds ratios (ORSD) for a standard deviation (SD) increment in each risk factor. The MR analysis indicated that higher body mass index increases the risk of RCC (ORSD: 1.56, 95% confidence interval [CI] 1.44–1.70), with comparable results for waist-to-hip ratio (ORSD: 1.63, 95% CI 1.40–1.90) and body fat percentage (ORSD: 1.66, 95% CI 1.44–1.90). This analysis further indicated that higher fasting insulin (ORSD: 1.82, 95% CI 1.30–2.55) and diastolic blood pressure (DBP; ORSD: 1.28, 95% CI 1.11–1.47), but not systolic blood pressure (ORSD: 0.98, 95% CI 0.84–1.14), increase the risk for RCC. No association with RCC risk was seen for lipids, overall type 2 diabetes, or fasting glucose.Conclusions: This study provides novel evidence for an etiological role of insulin in RCC, as well as confirmatory evidence that obesity and DBP influence RCC risk.
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| 21. |
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| 22. |
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| 23. |
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| 24. |
- Klose, M., et al.
(författare)
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From isolated GH deficiency to multiple pituitary hormone deficiency : an evolving continuum - a KIMS analysis
- 2009
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Ingår i: European Journal of Endocrinology. - 0804-4643 .- 1479-683X. ; 161, s. S75-S83
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To describe baseline clinical presentation, treatment effects and evolution of isolated GH deficiency (IGHD) to multiple pituitary hormone deficiency (MPHD) in adult-onset (AO) GHD. Design: Observational prospective study. Methods: Baseline characteristics were recorded in 4110 patients with organic AO-GHD, who were GH naive prior to entry into the Pfizer International Metabolic Database (KIMS: 283 (7%) IGHD, 3827 MPHD). The effect of GH replacement after 2 years was assessed in those with available follow-up data (1.33 IGHD, 2207 MPHD), and development of new deficiencies in those with available data on concomitant medication (165 IGHD, 3006 MPHD). Results: IGHD and MPHD patients had similar baseline clinical presentation, and both groups responded similarly to 2 years of GH therapy, with favourable changes in lipid profile and improved quality of life. New deficiencies were observed in 35%, of IGHD patients, which was similar to MPHD patients with one additional deficit other than GH. New deficiencies most often presented within the first year but were observed up to 6 years after GH commencement. Conversion of IGHD into MPHD was not predicted by aetiology, baseline characteristics, surgery or radiotherapy, whereas in MPHD additional deficits were predicted by age (P<0.001) and pituitary disease duration (P<0.01). Conclusion: Both AO-IGHD and -MPHD patients have similar baseline clinical presentation and respond equally well to 2 years of GH replacement. Hypopituitarism in adults seems to be a dynamic condition where new deficiencies can appear years after the initial diagnosis, and careful endocrine follow-up of all hypopituitary patients, including those with IGHD, is warranted.
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| 25. |
- Lazurova, I., et al.
(författare)
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Effect of Growth Hormone Replacement Therapy on Plasma Brain Natriuretic Peptide Concentration, Cardiac Morphology and Function in Adults with Growth Hormone Deficiency
- 2010
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Ingår i: Experimental and clinical endocrinology & diabetes. - : Georg Thieme Verlag KG. - 0947-7349 .- 1439-3646. ; 118:3, s. 172-176
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The impact of growth hormone (GH) replacement on plasma brain natriuretic peptide (BNP) in association with cardiac morphology and function in adults with growth hormone deficiency (GHD) was evaluated. Subjects and Methods: Fifty nine adult patients with GHD (29 men, age 19-59 years) received a starting dose of 0.1-0.2 mg/day recombinant GH, which was subsequently adjusted to the 50th percentile of normal serum insulin-like growth factor (IGF-1) over a 6 month period. Plasma BNP and IGF-I levels before, 3 and 6 months after treatment were determined, as were the echocardiographic data, such as ejection fraction (EF), left ventricular end-diastolic volume (LVEDV), left ventricular end-diastolic diameter (LVEDD), interventricular septal thickness (IVST), posterior wall thickness (PWT), left ventricular mass (LVM), E/A wave and deceleration time (DT). Results: Mean plasma BNP levels (53.1 +/- 8 pg/ml) and echocardiographic parameters were within the normal range at baseline, although men had higher LVM, IVST, PWT, LVEDV and LVEDD, respectively. A significant decrease in plasma BNP was observed after 6 months (27 +/- 5.6 pg/ml, P < 0.05). No significant changes in echocardiographic parameters were observed except for a mild tendency to increase in LVM, and a borderline decrease in DT (181 +/- 8.1 vs. 155 +/- 9 ms, P < 0.01). Conclusions: Six months GH replacement therapy induced a significant decrease in plasma BNP levels despite the majority of patients having plasma BNP within the normal range at baseline. A borderline decrease in diastolic deceleration time was observed, the clinical significance of which is unclear.
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| 26. |
- Nilsson, I, et al.
(författare)
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Denitrification of Water Using Immobilized Pseudomonas denitrificans Cells
- 1980
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Ingår i: European Journal of Applied Microbiology and Biotechnology. ; 10, s. 261-274
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Tidskriftsartikel (refereegranskat)abstract
- Preparations of living Pseudomonas denitrificans cells immobilized in alginate gel were used in the denitrification of water. In the presence of an exogenous carbon source the entrapped microorganisms reduced nitrate and nitrite to gaseous products and to achieve complete reduction, carbon to nitrogen ratios of over two were required. The effects on denitrification of particle size and the number of bacteria in the gel were investigated. Apparent Km values for nitrate and nitrite reduction were calculated for free and immobilized cells. When the immobilized cells were incubated in nutrient media, an increase in reduction rate was observed and this was shown to be caused by the growth of cells within the gel particles. Immobilized P. denitrificans cells retained 75% of their initial nitrate reduction capacity after 21 days of storage at +4°C. The operational stability of the alginate-immobilized cells was studied both in batch and in a column which was operated continuously. A column (45 g of alginate-cell fibers in 80 ml) denitrified a high nitrate drinking water (100 mg NO3/l) with a rate of 300 ml of nitrate and nitrite free water/day/g of gel. The half life for nitrate reduction was estimated to be 30 days.
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| 27. |
- Ogawa, Y., et al.
(författare)
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On the source of the polar wind in the polar topside ionosphere : First results from the EISCAT Svalbard radar
- 2009
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Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 36:24, s. L24103-
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Tidskriftsartikel (refereegranskat)abstract
- We present quantitative radar observations of both hydrogen ion (H+) and oxygen ion (O+) upflow in the topside polar ionosphere using measurements that were recently carried out with the EISCAT Svalbard Radar and the Reimei satellite. H+ upflow was clearly observed equatorward of the cusp above 500 km altitude. Within the cusp the H+ density was very low, and the upflow was dominated by O+ ions, but on closed field lines the H+ became the larger contributor to the upward flux above about 550 km. The total flux seemed to be conserved, and so below 550 km altitude O+ (with a small upward velocity of similar to 50 m s(-1)) appeared to determine the upward flux which was then maintained by H+! in the topside ionosphere. We also found that the H+ density in the topside polar ionosphere was several times higher than current predictions of ionospheric models like IRI2001.
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| 28. |
- Pulkki-Brännström, Anni-Maria, et al.
(författare)
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The equity impact of a universal child health promotion programme
- 2019
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Ingår i: European Journal of Public Health. - : Oxford University Press. - 1101-1262 .- 1464-360X. ; 29:Suppl 4, s. 103-103
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Background: We aimed to evaluate whether the Salut Programme, a universal child health promotion intervention, aimed to strengthen healthy lifestyles in northern Sweden, had any effect on income-related inequalities in positive birth outcomes for children and on healthcare use for children and their mothers.Methods: Mother’s residence and child’s date of birth determined whether the child and the mother belonged to the control group (areas that received care-as-usual) or the intervention group (areas with the intervention implemented from 2005), during the pre-measure period (children born 2002-2004) and the post-measure period (children born 2006-2008). The sum of parents’ taxable income was used for socioeconomic ranking. We computed the standard concentration index for six binary indicators of positive birth outcomes, and for inpatient and day patient care for children and mothers during the two years after delivery. Using a difference-in-difference approach, we assessed whether the extent of inequality changed over time between areas.Results: Income-related inequalities in child health status at birth and in child healthcare use were absent, except that full-term pregnancies were concentrated among the poor at pre-measure in the intervention group. However, mothers’ healthcare use was significantly pro-poor in the control group. The extent of inequality changed between pre- and post-measure periods for two outcomes: the pro-poor concentration of full-term pregnancies in the intervention group at pre-measure disappeared at post-measure; and an increase in pro-poor concentration of normal birth weight in the control group was not matched by a similar increase in the intervention group. Inequalities in healthcare use did not change significantly.Conclusions: Birth outcomes and child healthcare use seemed to be equitably distributed. However, the results raise concerns whether the intervention may have reduced the pro-poor concentration of positive birth outcomes.Key messagesThere are concerns that participation in universal health promotion programmes differs by socioeconomic status, although few public health interventions have been evaluated from an equity perspective.Birth outcomes and child healthcare use in Northern Sweden seemed to be equitably distributed across different socioeconomic groups.
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| 29. |
- Sjöberg, Richard L, et al.
(författare)
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Verbal fluency in patients receiving bilateral versus left-sided deep brain stimulation of the subthalamic nucleus for Parkinson's disease
- 2012
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Ingår i: Journal of the International Neuropsychological Society. - : Cambridge University Press. - 1355-6177 .- 1469-7661. ; 18:3, s. 606-611
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study was to investigate the relative effects of unilateral (left-sided) versus bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) on verbal fluency. To do this, 10 Parkinson's disease patients with predominantly bilateral motor symptoms who received bilateral STN DBS were compared with 6 patients suffering from predominantly unilateral symptoms who received STN DBS on the left side only. The results suggest that unilateral STN DBS of the speech dominant hemisphere is associated with significantly less declines in measures of verbal fluency as compared to bilateral stimulation. (JINS, 2012, 18, 606-611)
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| 30. |
- Wallstén, Elin, et al.
(författare)
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The Influence of Time Sampling on Parameters in the Logan Plot
- 2013
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Ingår i: 2013 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC). - 9781479905348
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Konferensbidrag (refereegranskat)abstract
- The Logan plot is a graphical method for reversible tracer bindings. The bias and uncertainties of this method have previously been analyzed with respect to noise, but little is known about the direct effects from varying the time sampling scheme. This study aims to investigate the effect of time sampling on the binding potential from the reference Logan plot. Image data from seven healthy subjects imaged with [11C]raclopride was reconstructed into six dynamic series of equal length time frames with frame times between 15 s and 480 s. Images were reconstructed using both filtered back projection (FBP) and a resolution enhanced ordered subset expectation maximization (OSEM) algorithm, SharpIR. For each sampling scheme, the nondisplaceable binding potential (BPND) parameter was calculated from the reference Logan plot with cerebellum as a reference region. The variation in BPND was analyzed as percentage deviations from the BPND for the 480 s scheme. R-2 of the linear fit was also analyzed. Comparison between all sampling schemes showed that the largest deviation in BPND was 7.4% between the 15 s sampling scheme and the 480 s sampling scheme reconstructed with SharpIR. The corresponding deviation for FBP images was 1.6%. R-2 was highest for long time frames, but all R-2 values were above 0.997 in this study.
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| 31. |
- Zlomanczuk, J, et al.
(författare)
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Near-threshold pion production in pN collisions at CELSIUS
- 1998
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Ingår i: ACTA PHYSICA POLONICA B. - : ACTA PHYSICA POLONICA B, JAGELLONIAN UNIV, INST PHYSICS. ; , s. 3141-3148
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Konferensbidrag (refereegranskat)abstract
- The pp --> pp pi(o) and pn --> pp pi(-) reactions have been measured at 310, 320 and 340 MeV using the CELSIUS proton beam and H-1 and H-2 internal cluster-jet targets. The pi(o) production at 310 MeV has been fully analyzed and a significant deviation fr
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