| 1. |
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| 2. |
- Mårdberg, Peter, et al.
(författare)
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Using a formal high-level language and an automated manikin to automatically generate assembly instructions
- 2014
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Ingår i: International Journal of Human Factors Modelling and Simulation. - : InderScience Publishers. - 1742-5549. ; 4:3, s. 233-249
-
Tidskriftsartikel (refereegranskat)abstract
- This paper presents an approach to automatically generate predetermined motion time system (PMTS) based assembly instruction lists from simulations within digital human modelling (DHM) software. A formal high-level instruction language is used to instruct an automated manikin to perform assembly operations. The manikin, the language and the assembled objects are composed into a discrete model. In a post-computational step, the model is used to construct PMTS instruction lists by mapping the manikin motions, assembled objects and the language instructions onto a set of PMTS keywords. The described approach is implemented in the DHM software IMMA and tested on industrial cases of manual assembly in the automotive industry.
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| 3. |
- Arvidsson Segerkvist, Katarina, et al.
(författare)
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Automatic weighing as an animal health monitoring tool on pasture
- 2020
-
Ingår i: Livestock Science. - : Elsevier BV. - 1871-1413 .- 1878-0490. ; 240
-
Tidskriftsartikel (refereegranskat)abstract
- This project aimed to evaluate a novel method for monitoring the health of grazing cattle. The method studied in this paper is based on an unmanned, automatic precision weighing system that can be used on pasture, and which will alarm farmers when animals show abnormal weight gain curves. The project focused primarily on the detection of pasture-borne nematode parasite infections, which clearly reduce the weight gain of calves, but the method could be further developed to include other diseases that impair animal performance. The early detection of nematode infections would both improve animal welfare and minimize the use of anthelmintics. This study included a total of 63 first season grazing steers born from dairy cows that were allocated to one of two permanent semi-natural pasture enclosures for 20 weeks. Both enclosures had two identical scales except that one scale was powered with line current and one scale was equipped with solar panels. The automatic weighing stations were situated in close proximity to a source of water, salt and minerals so that animals would voluntarily pass through them on a regular basis. LiveStock Planner (R) software was used to identify usable data. The number of usable recordings per animal throughout the grazing season varied from 547 to 2677 amongst the four weighing stations, with an average of five usable recordings per animal obtained each week. The herds were guided to the weighing area on a daily basis during the first eight weeks of the grazing period to ensure that the steers received enough water. After this period, manual observations were used to verify that all animals entered the watering area without problems. The findings showed that the weighing technique worked well; hence, the developed method demonstrates great potential as an automatic supervision tool for grazing cattle. However, even though the summer of 2016 was quite dry, there was still water available in ditches and puddles. Accordingly, water alone was not a strong enough motivation to get cattle to pass through the weighing station into the watering area. Hence, in grazing areas with natural water sources, a reward more attractive than the water, salt and minerals used in this study is needed to ensure frequent voluntary passage of cattle through the scales.
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| 4. |
- Berg, Lotta, et al.
(författare)
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Digital tillsynsteknik i djurhållning utomhus
- 2020
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I enlighet med Jordbruksverkets förfrågan behandlar denna rapport tre områden för digital teknik vid övervakning och kontroll av djur som vistas utomhus på stora ytor: (1) kamerateknologi, t.ex. användning av drönare, (2) positioneringsteknologi som GPS och (3) teknologi för att styra djurens rörelser, som drivning med drönare och användning av s.k. virtuella stängsel. De tre teknikområdena överlappar delvis varandra. Digital tillsyn av utegående djur är beroende av att sensorer mäter det man tror att de mäter med tillräcklig noggrannhet och att data kan överföras och bearbetas till information som lagras och analyseras på ett säkert och korrekt sätt. Sådana teknologier benämns med samlingsnamnet ’Precision Livestock Farming’ (PLF). Användningen av informationen är avgörande för teknikens användbarhet i tillsyns- och djurskyddsarbete. Tillämpningarna är till viss del reglerade av gällande lagstiftning, exempelvis genom krav på tillsyn, begränsad användning av elektricitet för att styra djurs beteende, användning av obemannade luftfarkoster, d.v.s. drönare, samt åtgärder för att förhindra att utrustning skadar djuren eller påverkar deras hälsa och beteende. Inom PLF används en rad olika sensorer som direkt eller indirekt kan mäta djurens miljö och djurens beteende och fysiologiska tillstånd. Den teknologiska utvecklingen har främst varit inriktad på mjölkkor, fjäderfän och grisar och endast i liten utsträckning berört häst, får och get. För djur på bete är överföringen av data från en enhet på eller vid djuret till en mottagare särskilt problematisk p.g.a. stora avstånd, men det sker en snabb teknisk utveckling mot effektivare överföring. PLF-teknologin innebär i de flesta fall att djuren övervakas kontinuerligt och att avvikelser i t.ex. deras hälsotillstånd och välfärd i princip kan upptäckas i realtid, vilket ska ställas mot nuvarande lagkrav på tillsyn minst en eller två gånger dagligen. Sensorer kan ge information om ett stort antal fysiologiska tillstånd och beteenden. En av de vanligaste teknikerna är sensorer för aktivitet. Indirekt kan de också ge information om idissling, liggtid, stegantal och ättid och utlösa larm om exempelvis brunst, hälsoproblem, hälta och kalvning. Sensorer kan även placeras i förmagen hos idisslare (s.k. våmbolus) där de mäter våm-pH och kan larma om störningar i magfunktionen, eller utformas som termometrar som kan larma om hälsostörningar, kalvning och vattenintag eller mikrofoner som kan mäta idissling och larma om brunst, kalvning och onormalt idisslingsmönster. Med kamerateknik kan man mäta aktivitet, kroppsform och hudtemperatur, vilket kan ge information om ketosstatus, hull, hälta och juverhälsa. Kameror monterade på drönare kan användas för att lokalisera och räkna djur, bestämma deras position, habitatval och till viss del deras beteende, särskilt när djuren rör sig över stora arealer. Det finns flera elektroniska positioneringsteknologier varav passiv ’Radio Frequency Identification RFID’ är den vanligaste. Räckvidden är kort med denna teknik men den kan vara användbar om man t.ex. vill mäta hur ofta djuren besöker en vattenpost. Andra teknologier kan med hjälp av antenner följa djurens positioner i realtid. GPS-enheter monterade i halsband kan regelbundet registrera djurens geografiska position. Användningen av GPS har blivit relativt vanlig i renskötseln vilket tycks ha lett till en förbättrad arbetssituation för renskötarna. Positionering med GPS ger inte alltid exakta uppgifter men tekniken har visat sig användbar för studier av habitatval, sociala interaktioner och gruppdynamik. Med positionerna från GPS har man också kunnat styra djur till områden med bättre betestillgång. Med en tillräckligt frekvent bestämning av position med hjälp av GPS (ca en gång per minut) är det möjligt att bestämma betestiden för nötkreatur på ett tillförlitligt sätt. En användning av drönare i djurskötsel och djurtillsyn kan vara att med hjälp av kamera lokalisera djuren över stora ytor. Denna användning begränsas dock av nuvarande bestämmelser om att föraren måste ha ögontakt med drönaren. I renskötseln har drönare börjat användas för att förflytta djur men denna tillämpning är ännu inte juridiskt reglerad. Virtuella stängsel är strukturer som bestäms med kartkoordinater eller elektronisk sändare på marken. Stängslen fungerar som inhägnader, hinder eller gränser. Djuren mottar signaler (vanligen ljud) och stimuli (vanligen elstötar från ett halsband) som gör det möjligt för dem att lära sig var stängslet finns. I vetenskapliga studier har man med varierande framgång lyckats lära djuren att associera ljudsignaler och elstötar med en gräns som inte får passeras. Förmågan att lära sig skiljer mellan olika djurslag, liksom mellan individer. Det finns fortfarande många obesvarade frågeställningar om hur djur kan anpassa sig till virtuella stängselsystemet, liksom hur de påverkas, både under inlärningsfas och bruksfas.
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| 5. |
- Blom, Helena, 1970-, et al.
(författare)
-
Multiple violence victimisation associated with sexual ill health and sexual risk behaviours in Swedish youth
- 2016
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Ingår i: European journal of contraception & reproductive health care. - : Informa UK Limited. - 1362-5187 .- 1473-0782. ; 21:1, s. 49-56
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To address the associations between emotional, physical and sexual violence, specifically multiple violence victimisation, and sexual ill health and sexual risk behaviours in youth, as well as possible gender differences.Methods: A cross-sectional population-based survey among sexually experienced youth using a questionnaire with validated questions on emotional, physical, and sexual violence victimisation, sociodemographics, health risk behaviours, and sexual ill health and sexual risk behaviours. Proportions, unadjusted/adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were calculated.Results: The participants comprised 1192 female and 1021 male students aged 15 to 22 years. The females had experienced multiple violence (victimisation with two or three types of violence) more often than the males (21% vs. 16%). The associations between multiple violence victimisation and sexual ill health and sexual risk behaviours were consistent for both genders. Experience of/involvement in pregnancy yielded adjusted ORs of 2.4 (95% CI 1.5-3.7) for females and 2.1 (95% CI 1.3-3.4) for males, and early age at first intercourse 2.2 (95% CI 1.6-3.1) for females and 1.9 (95% CI 1.2-3.0) for males. No significantly raised adjusted ORs were found for non-use of contraceptives in young men or young women, or for chlamydia infection in young men.Conclusions: Several types of sexual ill health and sexual risk behaviours are strongly associated with multiple violence victimisation in both genders. This should be taken into consideration when counselling young people and addressing their sexual and reproductive health.
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| 6. |
- Blom, Helena, et al.
(författare)
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Strong association between earlier abuse and revictimization in youth
- 2014
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Ingår i: BMC Public Health. - : Springer Science and Business Media LLC. - 1471-2458. ; 14:14
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Tidskriftsartikel (refereegranskat)abstract
- Background: Violence victimization among youth is recognized as a public health problem. The objective was to analyze the risk pattern of emotional, physical, and sexual abuse during the past 12 months by gender, sociodemographic factors, health risk behaviors, and exposure to abuse before the age of 15, among young men and women attending youth health centers in Sweden.Methods: A cross-sectional survey was conducted using a nationally representative sample of youth health centers. A total of 2,250 young women and 920 young men aged 15-23 completed a self-administered questionnaire. Odds ratios (OR) and adjusted odds ratios (AOR) with 95% CI were calculated.Results: A consistent and strong association was noted between exposure to all types of violence during the past year and victimization before the age of 15 for all types of violence for both women and men. The only exceptions were childhood sexual victimization and sexual violence during the past year for men. Younger age was associated with all violence exposure for the women and with emotional violence for the men. For the women, drug use was associated with all types of violence, while the association with hazardous alcohol use and not living with parents was restricted to physical and sexual violence exposure, present smoking was restricted to emotional and physical violence exposure, and partnership and living in urban areas were restricted to sexual violence. For men, not being partnered, hazardous alcohol consumption, and drug use meant increased risk for physical violence, while smoking and living in urban areas were associated with sexual violence. After adjustment, immigration had no association with violence exposure.Conclusions: Violence victimization in young men and women is often not a single experience. Findings underline the importance of early interventions among previously abused youth.
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| 7. |
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| 8. |
- Bohlin, Robert, et al.
(författare)
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Unified solution of manikin physics and positioning - Exterior root by introduction of extra parameters
- 2011
-
Ingår i: Proceedings of DHM, First International Symposium on Digital Human Modeling. - : Université Claude Bernard Lyon. - 9782953951509
-
Konferensbidrag (refereegranskat)abstract
- Simulating manual assembly operations considering ergonomic load and clearance demands requires detailed modeling of human body kinematics and motions, as well as a tight coupling to powerful algorithms for collision-free path planning. The focus in this paper is kinematics including balance and contact forces, and ergonomically preferable motions in free space. A typical manikin has more than 100 degrees of freedom. To describe operations and facilitate motion generation, the manikin is equipped with coordinate frames attached to end-effectors like hands and feet. The inverse kinematic problem is to find joint values such that the position and orientation of hands and feet matches certain target frames during an assembly motion. This inverse problem leads to an underdetermined system of equations since the number of joints exceeds the end-effectors' constraints. Due to this redundancy there exist a set of solutions, allowing us to consider ergonomics aspects and maximizing comfort when choosing one solution.The most common approach to handle both forward and inverse kinematics is building a hierarchy of joints and links where one root must be defined. A popular place to define the root is in a body part, e.g. in a foot. This leads to a two-step procedure; (i) one level determining when to re-root when moving the root part, (ii) then the Penrose pseudoinverse is used to match the end-effectors' constraints.In this paper we propose using a fixed exterior root by introducing six additional parameters positioning the lower lumbar - three rotations and three translations. This makes it possible to reposition the manikin without a series of re-rooting operations. Another important aspect is to keep the manikin, affected by internal and external forces and moments, in balance. However, by utilizing the exterior root and its added degrees of freedom it is possible to solve the balance, positioning, contact force and comfort problems simultaneously in a unified way. A manikin was implemented, and two test cases demonstrate the applicability of the presented method.
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| 9. |
- Brolin, Erik, 1984-, et al.
(författare)
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Development of body shape data based digital human models for ergonomics simulations
- 2022
-
Ingår i: Proceedings of the 7th International Digital Human Modeling Symposium (DHM 2022), August 29–30, 2022, Iowa City, Iowa, USA. - : University of Iowa Press. - 9780984037841 ; , s. 1-9
-
Konferensbidrag (refereegranskat)abstract
- This paper presents the development of body-shape-data-based digital human models, i.e. manikins, for ergonomics simulations. In digital human modeling (DHM) tools, it is important that the generated manikin models are accurate and representative for different body sizes and shapes as well as being able to scale and move during motion simulations. The developed DHM models described in this paper are based on body scan data from the CAESAR anthropometric survey. The described development process consists of six steps and includes alignment of body scans, fitting of template mesh through homologous body modeling, statistical prediction of body shape, joint centre prediction, adjustment of posture to T-pose, and, finally, generation of a relation between predicted mesh and manikin mesh. The implemented method can be used to create any type of manikin size that can be directly used in a simulation. To evaluate the results, a comparison was done of original body scans and statistically predicted meshes generated in an intermediary step, as well as the resulting DHM manikins. The accuracy of the statistically predicted meshes are relatively good, even though differences can be seen, mostly related to postural differences and differences around smaller areas with distinct shapes. The biggest differences between the final manikin models and the original scans can be found in the shoulder and abdominal areas, in addition to the significantly different initial posture that the manikin models have. To further improve and evaluate the generated manikin models, additional body scan data sets that include more diverse postures would be useful. DHM tool functionality could also be improved to enable evaluation of the accuracy of the generated manikin models, possibly resulting in DHM tools that are more compliant with standard documents. At the same time, standard documents might need to be updated in some aspects to include more three-dimensional accuracy analysis.
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| 10. |
- Danielson, Johan, 1975-, et al.
(författare)
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Percutaneous Hernia Repair in Children : Safe to introduce
- 2021
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Ingår i: Scandinavian Journal of Surgery. - : Sage Publications. - 1457-4969 .- 1799-7267. ; 110:3, s. 380-385
-
Tidskriftsartikel (refereegranskat)abstract
- Background and objective:In 2014 we introduced percutaneous internal ring suture as an alternative to open surgery for the treatment of inguinal hernia. This study aims to evaluate the introduction of the procedure at our institution.Methods:In total, 100 consecutive patients operated with percutaneous internal ring suture were compared with 100 consecutive patients operated with open surgery. The patients were operated from August 2014 until November 2017. Patient demographics, clinical history, operative time, time in theater, and postoperative complications were extracted from charts.Results:The mean operative time for percutaneous internal ring suture was 26.54 min and for open surgery 39.94 min, P < 0.0001. The total mean operative theater time for percutaneous internal ring suture was 108.95 min and for open surgery 118.4 min, P = 0.0343. During follow-up, two percutaneous internal ring sutures were operated for recurrent hernia. In the open surgery-group, three patients were operated for recurrent hernia, three for secondary testicular retention, and three for metachronous contralateral hernia.Conclusions:Even when established as a new technique, the percutaneous internal ring suture procedure is safe and results in shorter operative time and shorter theater time compared to open surgery.
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| 11. |
- Delfs, Niclas, et al.
(författare)
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Introducing Stability of Forces to the Automatic Creation of Digital Human Postures
- 2013
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Ingår i: 2nd International Digital Human Modeling.
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Konferensbidrag (refereegranskat)abstract
- Although the degree of automation is increasing in manufacturing industries, many assembly operations are performed manually. To avoid injuries and to reach sustainable production of high quality, comfortable environments for the operators are vital. Poor station layouts, poor product designs or badly chosen assembly sequences are common sources leading to unfavorable poses and motions. To keep costs low, preventive actions should be taken early in a project, raising the need for feasibility and ergonomics studies in virtual environments long before physical prototypes are available. Today, in the automotive industries, such studies are conducted to some extent. The full potential, however, is far from reached due to limited software support in terms of capability for realistic pose prediction, motion generation and collision avoidance. As a consequence, ergonomics studies are time consuming and are mostly done for static poses, not for full assembly motions. Furthermore, these ergonomic studies, even though performed by a small group of highly specialized simulation engineers, show low reproducibility within the group.Effective simulation of manual assembly operations considering ergonomic load and clearance demands requires detailed modeling of human body kinematics and motions as well as a fast and robust inverse kinematics solver. In this paper we introduce a stability measure rewarding poses insensitive to variations in contact points and contact forces. Normally this has been neglected and only the balance of moment and forces has been taken into account. The manikin used in this work has 162 degrees of freedom and uses an exterior root. To describe operations and facilitate motion generation, the manikin is equipped with coordinate frames attached to end-effectors like hands and feet. The inverse kinematic problem is to find joint values such that the position and orientation of hands and feet matches certain target frames during an assembly motion. This inverse problem leads to an underdetermined system of equations since the number of joints exceeds the end-effectors’ constraints. Due to this redundancy there exist a set of solutions, allowing us to pick a solution that maximizes a scalar valued comfort function. Many objectives are included in the comfort function, for example in terms of joint angles, joint moments and solid objects’ distance to the manikin. The proposed stability measure complements the earlier balance criterion and is combined into the comfort function. By increasing the importance of this function the digital human model will reposition to a more stable pose. The digital human model will be tested on a set of challenging assembly operations taken from the automotive industry to show the effect of the stability measure.
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| 12. |
- Gaziano, Liam, et al.
(författare)
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Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
- 2021
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Ingår i: Nature Medicine. - : Springer Nature. - 1078-8956 .- 1546-170X. ; 27:4
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Tidskriftsartikel (refereegranskat)abstract
- Large-scale Mendelian randomization and colocalization analyses using gene expression and soluble protein data for 1,263 actionable druggable genes, which encode protein targets for approved drugs or drugs in clinical development, identify IFNAR2 and ACE2 as the most promising therapeutic targets for early management of COVID-19. Drug repurposing provides a rapid approach to meet the urgent need for therapeutics to address COVID-19. To identify therapeutic targets relevant to COVID-19, we conducted Mendelian randomization analyses, deriving genetic instruments based on transcriptomic and proteomic data for 1,263 actionable proteins that are targeted by approved drugs or in clinical phase of drug development. Using summary statistics from the Host Genetics Initiative and the Million Veteran Program, we studied 7,554 patients hospitalized with COVID-19 and >1 million controls. We found significant Mendelian randomization results for three proteins (ACE2, P = 1.6 x 10(-6); IFNAR2, P = 9.8 x 10(-11) and IL-10RB, P = 2.3 x 10(-14)) using cis-expression quantitative trait loci genetic instruments that also had strong evidence for colocalization with COVID-19 hospitalization. To disentangle the shared expression quantitative trait loci signal for IL10RB and IFNAR2, we conducted phenome-wide association scans and pathway enrichment analysis, which suggested that IFNAR2 is more likely to play a role in COVID-19 hospitalization. Our findings prioritize trials of drugs targeting IFNAR2 and ACE2 for early management of COVID-19.
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| 13. |
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| 14. |
- Guzhva, Oleksiy, et al.
(författare)
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Hide ‘n seek: individual behavioural responses of cattle excreting different amounts of nematode eggs—potential threshold for pasture contamination assessment
- 2024
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Ingår i: Frontiers in animal science. - 2673-6225. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to investigate how the activity of cattle under natural grazing conditions is related to their individual parasite contribution (IPC). Potentially, the individuals contributing the most to the contamination of the pasture with gastrointestinal nematodes (GIN) could then be identified and selectively treated based on sensor data thresholds. A total of 58 steers of the dairy breeds Swedish Red (SR, n = 19) and Swedish Holstein (SH, n = 39) were used for sensor-based data collection that lasted for a total of 10 weeks from 4 May to 13 July 2022. All steers were inoculated with a priming dose of nematode larvae and weighed in conjunction with the pasture release. The animals were then divided into four experimental groups and treated with ivermectin (IVM PO, Boehringer Ingelheim, 0.5 mg/kg BW) at different intervals to obtain an exposure contrast (Group A was left untreated, Group B/IVM PO-4w was treated after 4 weeks, Group C/IVM PO-8w was treated after 8 weeks, and Group D/IVM PO-4&8w was treated after 4 weeks and then after 8 weeks). The steers were weighed on four further occasions, during which faecal samples were also taken for parasite testing. Activity data were collected using leg-mounted IceQube sensors and body weight data and faecal samples were collected bi-weekly. The new threshold metric (IPC) was proposed for individuals with different faecal egg count (FEC) levels [NO (no contribution) <20 EPG, LO (low contribution) = 20–150 EPG, ME (medium contribution) = 150–250 EPG, and HI (high contribution) ≥250 EPG] The effects of IPC on activity patterns were analysed stepwise using a Generalised Estimating Equations model implemented in Python programming language. Results showed significant effects of different IPC values on motion index and number of steps taken (adjusted p-value of 0.008, 0.018, 0.041, and 0.001 for individuals with NO, LO, ME, and HI IPC values, respectively). There were some breed effects on the average number of steps and minutes spent lying. The results also provide alternative threshold methods aimed at finding more sustainable ways of using anthelmintics and integrating individual data into future parasite control strategies.
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| 15. |
- Hanson, Lars, et al.
(författare)
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Design concept evaluation in digital human modeling tools
- 2022
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Ingår i: Proceedings of the 7th International Digital Human Modeling Symposium (DHM 2022), August 29–30, 2022, Iowa City, Iowa, USA. - : University of Iowa Press. - 9780984037841 ; , s. 1-9
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Konferensbidrag (refereegranskat)abstract
- In the design process of products and production systems, the activity to systematically evaluate initial alternative design concepts is an important step. The digital human modeling (DHM) tools include several different types of assessment methods in order to evaluate product and production systems. Despite this, and due to the fact that a DHM tool in essence is a computer-supported design and analysis tool, none of the DHM tools provide the functionality to, in a systematic way, use the results generated in the DHM tool to compare design concepts between each other. The aim of this paper is to illustrate how a systematic concept evaluation method is integrated in a DHM tool, and to exemplify how it can be used to systematically assess design alternatives. Pugh´s method was integrated into the IPS software with LUA scripting to systematically compare design concepts. Four workstation layout concepts were generated by four engineers. The four concepts were systematically evaluated with two methods focusing on human well-being and two methods focusing on system performance and cost. The result is very promising. The demonstrator illustrates that it is possible to perform a systematic concept evaluation based on human well-being, overall system performance, and other parameters, where some of the data is automatically provided by the DHM tool and other data manually. The demonstrator can also be used to evaluate only one design concept, where it provides the software user and the decision maker with an objective and visible overview of the success of the design proposal from the perspective of several evaluation methods.
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| 16. |
- Hanson, Lars, et al.
(författare)
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Industrial path solutions - intelligently moving manikins
- 2019
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Ingår i: DHM and Posturography. - London : Academic Press. - 9780128167137 ; , s. 115-124
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- IPS IMMA (Industrial Path Solutions - Intelligently Moving Manikins) is a digital human modeling tool developed in close cooperation between academia and industry in Sweden. The academic consortium behind the software consists of expertise within applied mathematics, ergonomics, and engineering. The development of IMMA was initiated from the vehicle industries’ need of an effective, efficient, objective, and user-friendly software for verification of manufacturing ergonomics. The ‘Industrial path solutions - intelligently moving manikins’ chapter consists of two main sections: the first about the commercially available tool, and the second about current or recent research projects developing the software further. Commercial IPS IMMA is presented by describing the biomechanical model and appearance, anthropometrics module, motion prediction, instruction language, and ergonomics evaluation. The research projects focus on dynamic motions simulation, muscle modelling and application areas such as human-robot collaboration, occupant packaging, and layout planning.
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| 17. |
- Herlin, Anders Henrik, et al.
(författare)
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Animal welfare implications of digital tools for monitoring and management of cattle and sheep on pasture
- 2021
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Ingår i: Animals. - : MDPI AG. - 2076-2615. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- The opportunities for natural animal behaviours in pastures imply animal welfare benefits. Nevertheless, monitoring the animals can be challenging. The use of sensors, cameras, positioning equipment and unmanned aerial vehicles in large pastures has the potential to improve animal welfare surveillance. Directly or indirectly, sensors measure environmental factors together with the behaviour and physiological state of the animal, and deviations can trigger alarms for, e.g., disease, heat stress and imminent calving. Electronic positioning includes Radio Frequency Identification (RFID) for the recording of animals at fixed points. Positioning units (GPS) mounted on collars can determine animal movements over large areas, determine their habitat and, somewhat, health and welfare. In combination with other sensors, such units can give information that helps to evaluate the welfare of free-ranging animals. Drones equipped with cameras can also locate and count the animals, as well as herd them. Digitally defined virtual fences can keep animals within a predefined area without the use of physical barriers, relying on acoustic signals and weak electric shocks. Due to individual variations in learning ability, some individuals may be exposed to numerous electric shocks, which might compromise their welfare. More research and development are required, especially regarding the use of drones and virtual fences. © 2021 by the authors.
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| 18. |
- Högberg, Dan, 1965-, et al.
(författare)
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DHM Based Test Procedure Concept for Proactive Ergonomics Assessments in the Vehicle Interior Design Process
- 2018
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Ingår i: Proceedings of the 20th Congress of the International Ergonomics Association (IEA 2018). - Cham, Switzerland : Springer. - 9783319960760 - 9783319960777 ; , s. 314-323
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Konferensbidrag (refereegranskat)abstract
- The development of a digital human modelling (DHM) based test procedure concept for the assessment of physical ergonomics conditions in virtual phases of the vehicle interior design process is illustrated and discussed. The objective of the test procedure is to be a valuable tool for ergonomic evaluations and decision support along the design process, so that ergonomic issues can be dealt with in an efficient, objective and proactive manner. The test procedure is devised to support companies in having stable and objective processes, in accordance with lean product development (LPD) philosophies. The overall structure and fundamental functionality of the test procedure concept is explained by a simplified use case, utilizing the DHM tool IPS IMMA to: define manikin families and manikin tasks; predict manikin motions; and visualize simulations and ergonomics evaluation outcomes.
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| 19. |
- Högberg, Niclas, et al.
(författare)
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Assessment of three DNA extraction kits for the absolute quantification of strongyle nematode eggs in faecal samples
- 2022
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Ingår i: Acta Veterinaria Scandinavica. - : Springer Science and Business Media LLC. - 0044-605X .- 1751-0147. ; 64
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Tidskriftsartikel (refereegranskat)abstract
- Background Haemonchus contortus is one of the most pathogenic gastrointestinal nematodes of small ruminants. The current diagnostic approach for the detection of this species relies on coproscopic methods, which both have low sensitivity and are time consuming. Methods employing detection through DNA amplification, such as droplet digital polymerase chain reaction (ddPCR), offer an advantageous approach to the diagnosis of H. contortus. However, DNA extraction protocols need to be constantly updated for the optimal retrieval of diagnostically usable template. Here, we describe the evaluation of three genomic DNA extraction kits for the detection and quantification of H. contortus ITS2 amplicon DNA from faecal samples, using droplet digital PCR. Results DNA samples, extracted from faecal material with the Nucleospin DNA Stool kit, produced the highest amounts of ITS2 amplicon copies and had the lowest coefficient of variation across different dilutions and sample types (fresh or frozen) out of the tested kits (Nucleospin DNA Stool, E.Z.N.A.(R) Stool DNA Kit and QIAamp Fast DNA Stool Mini Kit). Furthermore, the protocol of this kit has the fewest number of steps and the price of DNA extraction per sample is reasonable (2.77 euro). Conclusions The Nucleospin DNA Stool kit is an attractive option for the detection and quantification of H. contortus DNA in faecal samples of small ruminants in a diagnostic setting.
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| 20. |
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| 21. |
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| 22. |
- Högberg, Niclas, 1979-
(författare)
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Experimental and Clinical Necrotizing Enterocolitis
- 2013
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Necrotizing enterocolitis (NEC), a severe inflammatory disorder of the gastrointestinal tract with high morbidity and mortality, affects primarily preterm infants. The diagnosis represents a challenging task, and no biomarker has been found to aid early diagnosis with high accuracy. Microdialysis has been widely used to detect metabolites of anaerobic metabolism, enabling a local and early detection of ischemia. This thesis aims to evaluate the possibility of detecting intestinal ischemic stress in experimental and clinical NEC, by use of rectal intraluminal microdialysis.Intraluminal rectal microdialysis was performed on rats subjected to total intestinal ischemia. Metabolites of ischemia were detectable in both ileum and rectum, with raised glycerol concentrations and lactate/pyruvate ratios. Elevated concentrations of glycerol correlated to increasing intestinal histopathological injury.Experimental early NEC was induced in newborn rat pups, by hypoxia/re-oxygenation treatment. Development of NEC was confirmed by histopathology. Elevated glycerol concentrations were detected by rectal microdialysis.The genetic alterations following experimental NEC in rat pups were studied with microarray. Immunohistochemistry staining was performed for tight junction proteins claudin-1 and claudin-8. Several genes were altered in experimental NEC, mainly genes regulating tight junctions and cell adhesion. Immunohistochemistry revealed reduced expression of claudin-1.A prospective study was conducted on preterm infants with a gestational age of less than 28 weeks. The infants were admitted to a neonatal intensive care unit, and observed during a 4-week period. Rectal microdialysis was performed twice a week, and blood was drawn for analysis of I-FABP. A total of 15 infants were included in the study, whereof four infants developed NEC, and 11 served as controls. Rectal glycerol and I-FABP displayed high concentrations, which varied considerably during the observation periods, both in NEC and controls. No differences in either glycerol or I-FABP concentrations were seen in the NEC-group vs. the controls.In conclusion, rectal microdialysis can detect metabolites of intestinal ischemia, both in experimental and clinical NEC. Rectal microdialysis is safe and could provide a valuable non-invasive aid to detect hypoxia-induced intestinal damage or ischemic stress in extremely preterm infants. In this study however, it was not possible to predict the development of clinical NEC using microdialysis or I-FABP.
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| 23. |
- Högberg, Niclas, 1979-, et al.
(författare)
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Genes regulating tight junctions and cell adhesion are altered in early experimental necrotizing enterocolitis
- 2013
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Ingår i: Journal of Pediatric Surgery. - : Elsevier BV. - 0022-3468 .- 1531-5037. ; 48:11, s. 2308-2312
-
Tidskriftsartikel (refereegranskat)abstract
- Background/purpose:Necrotizing enterocolitis (NEC) represents one of the gravest complications in preterm infants and carries significant morbidity and mortality. Increased intestinal permeability may play an important role in the pathogenesis of NEC. In this study we investigated the genes regulating structural proteins such as tight junctions (TJ) and cell adhesion in a neonatal rat model of early NEC, as well as the expression of TJ proteins by immunohistochemistry staining.Methods:The studies were performed on Sprague-Dawley rat pups. Experimental NEC was induced using hypoxia/reoxygenation treatment on day 1 after birth. Intestinal specimens from the ileum were obtained, mRNA was purified and the transcriptome was analyzed using microarray. Immunohistochemistry staining was performed for TJ proteins.Results:We found several TJ genes such as claudins 1, 8, 14, 15 and gap junction protein to be affected. Immunohistochemistry staining for TJ protein claudin-1 revealed decreased levels in experimental NEC compared to controls. Alterations in genes involved in the inflammatory response was confirmed, along with several genes regulating proteins used as biomarkers for NEC.Conclusion:This study indicates that tight junctions and cell adhesion may play a critical role in the pathogenesis of early experimental NEC. Better understanding of the pathogenesis of NEC may lead to novel strategies for the prevention and treatment of NEC.
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| 24. |
- Högberg, Niclas, 1979-, et al.
(författare)
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Intestinal intraluminal glycerol and plasma I-FABP levels in preterm infants with necrotizing enterocolitis
- 2016
-
Ingår i: Clinics in Surgery. ; 1:1085, s. 1-6
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Tidskriftsartikel (refereegranskat)abstract
- Background/Purpose: Necrotizing enterocolitis (NEC) is highly associated with prematurity and is characterized by bowel necrosis and multi-organ failure. There is a strong need for improved diagnostic methods to reduce the significant morbidity and mortality associated with NEC. The aim of this single centre prospective study was to investigate the possibility to detect early signs of NEC, by using rectal intraluminal microdialysis and plasma intestinal fatty acid binding protein (I-FABP) in preterm infants admitted to a level III neonatal intensive care unit.Methods: The study was performed on extremely preterm infants with a gestational age of less than 28 weeks. During a 4-week period after birth, rectal intraluminal microdialysate levels of glucose, lactate, pyruvate and glycerol were measured, and plasma was collected for I-FABP analysis. Infants not developing NEC served as controls. Results: Microdialysis revealed signs of intestinal hypoxic or ischemic damage and cell membrane degradation, with a marked increase of both intraluminal glycerol and plasma I-FABP in infants developing NEC, as well as in infants suffering from other complications. The microdialysate levels of glucose, lactate and pyruvate were too low to be evaluated in this setting. All infants tolerated the microdialysis well without any complications.Conclusion: Elevated levels of intraluminal glycerol and plasma I-FABP suggests mucosal cell membrane degradation and hypoxic or ischemic damage in preterm infants developing NEC, as well as in preterm infants suffering from other complications such as volvulus, sepsis or respiratory distress. However, it was not possible to predict development of NEC before clinical diagnosis using these markers.
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| 25. |
- Högberg, Niclas, 1979-, et al.
(författare)
-
Intestinal ischemia measured by intraluminal microdialysis
- 2012
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Ingår i: Scandinavian Journal of Clinical and Laboratory Investigation. - : Informa UK Limited. - 0036-5513 .- 1502-7686. ; 72:1, s. 59-66
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Tidskriftsartikel (refereegranskat)abstract
- Objective. To evaluate the possibility of detecting intestinal ischemia by intraluminal microdialysis and comparing the ileum and colon. Methods. The studies were performed on male Sprague-Dawley rats. In the fi rst part of the study, microdialysis catheters were placed in the sigmoid part of the colon and in the subcutaneous adipose tissue. In the second part of the study, microdialysis catheters were placed in the lumen of the ileum and the colon. The infrarenal aorta was clamped proximal to the cranial mesenteric artery. Microdialysate levels of glucose, lactate, pyruvate and glycerol were measured. Intestinal specimens were removed at the end of the ischemic period for microscopic evaluation. Results. Intraluminal microdialysis could detect early signs of ischemic injury in the ileum, as well as in the colon, with a marked increase of lactate, lactate/pyruvate ratio and glycerol. The increased levels of intraluminal glycerol showed a positive correlation to prolonged ischemia and to higher degrees of intestinal damage. Conclusion. Intraluminal measurement of glycerol is a good marker for intestinal ischemia. Intraluminal microdialysis in the colon is easily accessible through the rectum, and ay prove to be a valuable clinical tool for diagnosing intestinal ischemia.
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| 26. |
- Högberg, Niclas, 1979-, et al.
(författare)
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Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis
- 2012
-
Ingår i: Journal of Pediatric Surgery. - : Elsevier BV. - 0022-3468 .- 1531-5037. ; 47:9, s. 1646-1651
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND/PURPOSE:Necrotizing enterocolitis (NEC) represents one of the gravest complications in premature infants and carries significant morbidity and mortality. There is a great need for improved diagnostic methods to reduce the severity and incidence of NEC. The aim of the study was to investigate if intraluminal microdialysis can detect intestinal ischemia in newborn rats with induced experimental NEC.METHODS:The studies were performed on 1-day-old Sprague-Dawley rat pups. Experimental NEC was induced using hypoxia/reoxygenation treatment. Microdialysis catheters were rectally inserted and placed in the rectosigmoid part of the colon. Microdialysate levels of glucose, lactate, pyruvate, and glycerol were measured. Intestinal specimens were collected at the end of the experiments for microscopic evaluation.RESULTS:Intraluminal microdialysis revealed signs of intestinal hypoxia and cellular damage, with a marked increase of lactate and glycerol. Microscopic evaluation confirmed intestinal damage in the NEC group.CONCLUSION:Intraluminal microdialysis can detect intestinal hypoxic stress and mucosal cell membrane decay in a rat model of NEC. Intestinal intraluminal microdialysis is easily accessible through the rectum and may be a useful noninvasive complement to other methods in the assessment of NEC.
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| 27. |
- Högberg, Niclas, et al.
(författare)
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Nematode parasitism affects lying time and overall activity patterns in lambs following pasture exposure around weaning
- 2021
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Ingår i: Veterinary Parasitology. - : Elsevier BV. - 0304-4017 .- 1873-2550. ; 296
-
Tidskriftsartikel (refereegranskat)abstract
- We investigated the effects of gastrointestinal nematode (GIN) challenge on activity in first season grazing lambs naturally exposed to two different levels of multispecies GIN infections. Ewes and their twin-born lambs were turned-out to graze in two permanent pasture enclosures naturally contaminated with GIN the previous year, thereby exposing them to overwintering strongyle larvae. Animals in the low parasite exposure group (LP) were dewormed monthly with 0.2 mg ivermectin (Ivomec (R) vet, oral suspension) per kg body weight, whereas those in high parasite exposure group (HP) were left untreated. At weaning, lambs were allocated to one out of four groups based on weight and sex (HPE, n = 15; HPR, n = 15; LPE, n = 14; LPR, n = 14), in four nearby noncontaminated ley enclosures of similar size. Activity patterns were monitored from day -7, i.e. 7 days preweaning, until day 49, i.e. 49 days post-weaning, by fitting all lambs with IceQube sensors (IceRobotics). Body weight was monitored weekly from day -21, whereas faecal samples were investigated at days -21, 7, 35 and 49 for nematode faecal egg counts (EPG) using McMaster-technology and a validated Droplet Digital PCR protocol to determine nematode composition. All statistical analyses were performed in R studio, using mixed models with repeated measures. In the data analyses, weekly recordings was treated as a period, generating a total of eight periods. Average daily lying time had a significant interaction between parasite exposure and period (P = 0.0013), with animals in HP having a 101 +/- 31 min shorter daily lying time compared to LP. Motion Index (MI; absolute value of the 3-D acceleration) had a significant interaction between parasite exposure and period (P = 0.0001) with lambs in group HP having a lower average daily MI compared with LP. Both body weight gain and EPG levels were significantly different (P< 0.0001) between HP and LP groups during the course of the study. The molecular investigation showed that animals were predominantly infected with Teladorsagia spp., combined with low proportions of Haemonchus spp. In conclusion, this study shows that lying time and Motion Index of lambs around weaning was affected by moderate nematode infections. This indicates that there is a potential use of automated behaviour recordings as a diagnostic tool for detection of nematode parasites in lambs even at moderate infection levels.
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| 28. |
- Högberg, Niclas
(författare)
-
Sensing the worms : automated behaviour monitoring for detection of parasitism in grazing livestock
- 2021
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Gastrointestinal nematodes (GIN) are common in grazing livestock and is a major cause of impaired health and productivity. Current control practices of GIN infections depend largely on the use of anthelmintic drugs. However, misuse of anthelmintic drugs has led to a widespread development of anthelmintic resistance. Behavioural monitoring has been suggested as a novel method to detect parasite infection in grazing livestock, enabling targeted (selective) treatment, where only infected groups or individual animals within a group are treated. The aim of this thesis was to investigate how multispecies GIN parasite infections affect behavioural patterns in grazing livestock on a group level using different on-animal sensors. The effect of subclinical GIN infection on activity and rumination patterns in first season grazing steers were investigated in contrasting groups during two grazing seasons, using different commercial sensors. The results indicate that untreated steers exposed to a higher GIN level had an increased lying time, lower activity level and affected rumination patterns over time, compared with dewormed steers. To enable the assessment of behavioural responses in lambs, the validity of two sensors for cattle for use in lambs were first evaluated. The effect of subclinical GIN infection on activity in lambs around weaning was then investigated in a replicated grazing trial with treated and untreated groups. The results indicate untreated lambs had a shorter daily lying time over time as well as a lower activity level, compared with dewormed lambs. In conclusion, this thesis supports that behavioural patterns are affected by subclinical GIN infections and the results demonstrate the potential use of automated behavioural observations as a diagnostic tool.
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| 29. |
- Högberg, Niclas, et al.
(författare)
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Subclinical nematode parasitism affects activity and rumination patterns in first-season grazing cattle
- 2021
-
Ingår i: Animal. - : Elsevier BV. - 1751-7311 .- 1751-732X. ; 15
-
Tidskriftsartikel (refereegranskat)abstract
- Sickness behaviour has been suggested as an applicable indicator for monitoring disease. Deviating feeding behaviour and activity can provide information about animals' health and welfare status. Recent advances in sensor technology enable monitoring of such behaviours and could potentially be utilized as an indicator of gastrointestinal nematode (GIN) infections. This study investigated activity and rumination patterns in first-season grazing steers exposed to subclinical infection levels of the GIN Ostertagia ostertagi and Cooperia oncophora. At turnout, animals were allocated to one of four experimental groups and were faced with "high" (H1, n = 15; H2, n = 17) or "low" (L1, n = 17; L2, n = 11) levels of parasite exposure by grazing in similar enclosures contaminated with overwintering third stage (13) GIN larvae. Animals in H1 and H2 (HP) received a 1:1 mix of approximately 10,000 0. ostertagi and C. oncophora L3 at turnout; whereas the animals in Ll and L2 (LP) were treated monthly with ivermectin. Activity and rumination patterns were monitored by fitting animals with leg- (IceQube) and neck-mounted (Heatime) sensors. BW was recorded every fortnight, whereas faecal and blood samples were examined every four weeks for nematode faecal egg count and serum pepsinogen concentrations (SPCs). There was an interaction effect of exposure level and period (P < 0.0001) on average lying daily time across the entire grazing time. A higher mean daily lying time (P = 0.0037) was found in HP compared with LP during the first 40 days on pasture. There was also interaction effects of treatment and day since turnout on rumination time (P < 0.0001) and rumination change (P = 0.0008). Also mean daily steps (P < 0.0001) and mean daily motion index (P < 0.0001) were markedly higher in HP during days 62-69, coinciding with peaking SPC in HP. Strongyle eggs were observed both in HP and LP from 31 days after turnout. Eggs per gram (EPG) differed between parasite exposure levels (P < 0.0001), with mean EPG remaining low in LP throughout the experiment. Similarly, an increase in SPC was observed (P < 0.0001), but only in HP where it peaked at day 56. In contrast, no difference in BW gain (BWG) (P = 0.78) between HP and LP was observed. In conclusion, this study shows that behavioural measurements monitored with sensors were affected even at low infection levels not affecting BWG. These combined results demonstrate the potential of automated behavioural recordings as a tool for detection of subclinical parasitism. (C) 2021 The Authors. Published by Elsevier B.V. on behalf of The Animal Consortium.
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| 30. |
- Högberg, Niclas, et al.
(författare)
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The effect of weaning age on animal performance in lambs exposed to naturally acquired nematode infections
- 2023
-
Ingår i: Veterinary Parasitology. - : Elsevier BV. - 0304-4017 .- 1873-2550. ; 316
-
Tidskriftsartikel (refereegranskat)abstract
- The effects of mixed gastrointestinal nematode (GIN) infections on animal growth and post-weaning activity patterns were investigated in grazing intact ram lambs when naturally exposed to two different infection levels and weaned at different ages. Ewes and their twin-born lambs were turned-out to graze in two permanent pasture enclosures naturally contaminated with GIN the previous year. Ewes and lambs in the low parasite exposure group (LP) were drenched before turn-out and at weaning, respectively, with 0.2 mg ivermectin per kg body weight, whereas those in the high parasite exposure group (HP) were left untreated. Two weaning ages were applied, early weaning (EW) (10 weeks) and late weaning (LW) (14 weeks), respectively. The lambs were then allocated to one out of four groups based on parasite exposure level and weaning age (EW-HP, n = 12; LW-HP, n = 11; EW-LP, n = 13; LW-LP, n = 13). Body weight gain (BWG) and faecal egg counts (FEC) were monitored, in all groups, from the day of early weaning and every four weeks, for 10 weeks. In addition, nematode composition was determined using droplet digital PCR. Activity patterns measured as Motion Index (MI; the absolute value of the 3D acceleration) and lying time were monitored continuously from the day of weaning until four weeks postweaning using IceQube (R) sensors. Statistical analyses were performed in RStudio, using mixed models with repeated measures. BWG was 11% lower in EW-HP compared with EW-LP (P = 0.0079) and 12% lower compared with LW-HP (P = 0.018), respectively. In contrast, no difference in BWG was observed between LW-HP and LW-LP (P = 0.97). The average EPG was higher in EW-HP compared with EW-LP (P < 0.001), as well as in EW-HP compared with LW-HP (P = 0.021), and LW-HP compared with LW-LP (P = 0.0022). The molecular investigation showed that animals in LW-HP had a higher proportion of Haemonchus contortus compared with EW-HP. MI was 19% lower in EW-HP compared with EW-LP (P = 0.0004). Daily lying time was 15% shorter in EW-HP compared with EW-LP (P = 0.0070). In contrast, no difference in MI (P = 0.13) and lying time (P = 0.99) between LW-HP and LW-LP was observed. The results suggest that a delayed weaning age may reduce the adverse effects of GIN infection on BWG. Contrarily, an earlier weaning age may reduce the risk of H. contortus infection in lambs. Moreover, the results demonstrates a potential use of automated behaviour recordings as a diagnostic tool for the detection of nematode infections in sheep.
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| 31. |
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| 32. |
- Högberg, Niclas, et al.
(författare)
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Validation of accelerometers to automatically record postures and number of steps in growing lambs
- 2020
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Ingår i: Applied Animal Behaviour Science. - : Elsevier BV. - 0168-1591 .- 1872-9045. ; 229
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Tidskriftsartikel (refereegranskat)abstract
- We validated the accuracy of two commercially available activity loggers for cattle in determining lying and standing durations, number of lying bouts and number of steps in growing lambs. Ten growing lambs divided into two weight classes were fitted with an IceTag on the right hind leg and an IceQube on the left hind leg. The IceTag reports activity per second, whereas the IceQube reports activity in 15-min periods. To enable comparison between loggers, IceTag data were also summarized in 15-min periods. Computed indications for the start of a lying bout of durations > 10 s and > 30 s was performed to enable filtering of lying bout data. Analyses of the lambs body posture and number of steps per second from 50 h of video recordings were used as a gold standard to determine the accuracy of the two loggers. Two observers scored the two different groups and interobserver reliability was consistent for standing, lying and number of lying bouts (kappa = 0.99). However, the observers defined step count differently and no agreement was found (kappa = -0.05; -0.11). Based on Bland-Altman comparison both loggers can be used to record standing and lying time. The positive predictive value (PPV), sensitivity and specificity of the IceTag compared to video recordings per second for standing and lying were all > 91.5 %. The IceTag showed a poor PPV ( < 44 %) and sensitivity ( < 91 %) for lying bouts, whereas the IceQube showed a better PPV ( < 92 %) but somewhat lower sensitivity ( < 88 %). The performance improved with the computed indications for lying bouts, for IceTag (LB_10: PPV: 100 %; sensitivity: 89 %; LB_30: PPV: 100 %; sensitivity: 100 %) and IceQube (LB_10: PPV: 98 %; sensitivity: 89 %; LB_30: PPV: 100 %; sensitivity: 100 %)), respectively. However, based on Bland-Altman comparisons, no agreement between video recording and logger recordings could be found for step count. We conclude that both loggers are able to record standing and lying time accurately. However, the ability to record number of lying bouts is poorer for the IceTag than IceQube but increases if bouts < 30 s is disregarded. Furthermore, none of the loggers should be used for step count recordings.
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| 33. |
- Keyvani, Ali, et al.
(författare)
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Ergonomic Risk Assessment of a Manikin’s Wrist Movements - a Test Study in Manual Assembly
- 2013
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Konferensbidrag (refereegranskat)abstract
- Use of digital human modeling (DHM) tools enables early assessment of ergonomic risks in the production development process. This early risk assessment can indicate needs for preventive actions in order to decrease risks for work-related musculoskeletal disorders. A method for the assessment of physical workload has been developed, for the analysis of wrist joint data produced by a DHM tool. The method is tested in a simulation model of an actual manual assembly station in industry where it is assumed that physical workload problems exist. The results show that the method can be successfully applied on an industrial case. In addition, presumptive risks and possible diagnoses are predicted based on the similarity of the simulated task’s motions with motions from other known work class profiles stored in a database based on epidemiological research.
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| 34. |
- Kroese, Adrien, et al.
(författare)
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3-Dimensional pose estimation to detect posture transition in freestall-housed dairy cows
- 2024
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Ingår i: Journal of Dairy Science. - 0022-0302 .- 1525-3198. ; 107:9, s. 6878-6887
-
Tidskriftsartikel (refereegranskat)abstract
- Freestall comfort is reflected in various indicators, including the ability for dairy cattle to display unhindered posture transition movements in the cubicles. To ensure farm animal welfare, it is instrumental for the farm management to be able to continuously monitor occurrences of abnormal motions. Advances in computer vision have enabled accurate kinematic measurements in several fields such as human, equine and bovine biomechanics. An important step upstream to measuring displacement during posture transitions is to determine that the behavior is accurately detected. In this study, we propose a framework for detecting lying to standing posture transitions from 3D pose estimation data. A multi-view computer vision system recorded posture transitions between Dec. 2021 and Apr. 2022 in a Swedish stall housing 183 individual cows. The output data consisted of the 3D coordinates of specific anatomical landmarks. Sensitivity of posture transition detection was 88.2% while precision reached 99.5%. Analyzing those transition movements, breakpoints detected the timestamp of onset of the rising motion, which was compared with that annotated by observers. Agreement between observers, measured by intra-class correlation, was 0.85 between 3 human observers and 0.81 when adding the automated detection. The intra-observer mean absolute difference in annotated timestamps ranged from 0.4s to 0.7s. The mean absolute difference between each observer and the automated detection ranged from 1.0s to 1.3s. There was a significant difference in annotated timestamp between all observer pairs but not between the observers and the automated detection, leading to the conclusion that the automated detection does not introduce a distinct bias. We conclude that the model is able to accurately detect the phenomenon of interest and that it is equatable to an observer.
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| 35. |
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| 36. |
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| 37. |
- Ljung, Oskar, et al.
(författare)
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Integration of Simulation and Manufacturing Engineering Software - Allowing Work Place Optimization Based on Time and Ergonomic Parameters
- 2020
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Ingår i: DHM2020. - Amsterdam : IOS Press. - 9781643681047 - 9781643681054 ; , s. 342-347
-
Konferensbidrag (refereegranskat)abstract
- There is a constant strive in industry to be competitive on the market, to manufacture with quality and productivity. At the same time, it is important to offer workers a sustainable work life. Research has shown a clear relationship between poor ergonomics and productivity losses and quality deficiencies, e.g. due to assembly errors, which also causes large costs for companies. In spite of the abovementioned relationship, productivity, ergonomics and quality are commonly treated separately in factory, line and workstation planning. To improve the factory, line and workstation planning, make it more efficient, ergonomic and to improve quality this paper proposes a concept that enables line balancing that considers two parameters in parallel, assembly time and ergonomic load as well as add possibility for mathematical optimization. The concept has been developed in a participative and iterative process. Two software tools and a simulation platform, the digital human modelling tool IPS IMMA, the balancing tool AVIX and the optimization platform EPP, have been used to demonstrate the concept. An integrated solution is formed. The integrated demonstration tool shows promising results. The demonstrator provides the possibility to manually optimize ergonomics and time in parallel, a relatively unique functionality.
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| 38. |
- Novobilsky, Adam, et al.
(författare)
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Selective flukicide treatment of non-lactating cows and the corresponding production impact of Fasciola hepatica in dairy herds in Sweden
- 2020
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Ingår i: Veterinary Parasitology. - : Elsevier BV. - 0304-4017 .- 1873-2550. ; 283
-
Tidskriftsartikel (refereegranskat)abstract
- A control strategy against Fasciola hepatica infection based on selective treatment of non-lactating animals was evaluated in four Swedish dairy herds. The study was conducted over the course of two consecutive seasons in moderately to highly F. hepatica infected herds with robotic milking, where heifers and dry cows received an oral drench with albendazole (10 mg/kg) during three visits in January, February and March in both 2017 and 2018. This resulted in an anthelmintic coverage between 38 % and 58 % of the animals. Furthermore, on each visit, the infection status of all dewormed animals along with 15 randomly selected milking cows were monitored by detection of F. hepatica coproantigens. Individual milk samples were also collected quarterly from the whole herds for measurements of individual antibody levels against the parasite using milk ELISA. In addition, individual data on milk yield and quality were collected on a monthly basis between 2016 and 2018. To further study the impact of the infection on milk production, truly F. hepatica positive and negative cows in the first lactation were identified based on the results from coproantigen and milk ELISA assays. Total F. hepatica coproantigen prevalence in the herds varied between 28 % and 85 % in the first year, and between 27 % and 68 % in the second year of the study. We found that two years of treatments resulted in a significant decrease of coproantigen-positivity especially on the two most heavily infected farms. These results were confirmed by a similar drop in within-herd prevalences obtained by milk ELISA results. The infection had a significant negative impact on milk yields in untreated F. hepatica positive cows. No consistent long-term effect was observed at the herd level probably due to the influx of animals infected before puberty and/or adult animals that were re infected at dry-off. This is the first study of the effects of F. hepatica infection on milk yield and quality in dairy herds in Sweden.
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| 39. |
- Palm, Anna, et al.
(författare)
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Motivational interviewing does not affect risk drinking among young women : A randomised, controlled intervention study in Swedish youth health centres
- 2016
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Ingår i: Scandinavian Journal of Public Health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 44:6, s. 611-618
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The aim of this study was to analyse risk and binge drinking at 12-month follow-up in young women with risk drinking who received motivational interviewing compared with controls.Methods: Young women attending Swedish youth health centres were randomised into intervention or control groups. The intervention group members were asked about their alcohol consumption by a midwife/social worker using the Alcohol Use Disorders Identification Test Consumption. A score of 5 was used as the cut-off value for risk drinking. Participants with risk drinking in the intervention group received motivational interviewing within the same visit. Participants in the control group had a regular visit with a midwife/social worker and answered the same questions about alcohol consumption in a questionnaire after their visit. A questionnaire with the same questions was administered to participants 12 months after baseline.Results: Of 1445 eligible young women, 1051 (73%) consented to randomisation and were enrolled in the study. The follow-up rate was 54%. There was a significant decrease in risk- and binge drinking, from baseline to follow-up, in both the intervention and the control groups. Generalised estimating equation analyses demonstrated no significant effect between groups. Of participants who did not have risk drinking at baseline, about 20% in both groups had developed high-risk drinking by the 12-month follow-up.Conclusions: No significant differences in risk drinking between young women who received motivational interviewing and controls were found. There was a large intra-individual mobility in young women's risk drinking behaviour. This highlights the importance of finding reliable screening tools that can capture the mobility in drinking behaviour in youth. More research is needed before recommendations can be made.
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| 40. |
- Palm, Anna, et al.
(författare)
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No Differences in Health Outcomes After Routine Inquiry About Violence Victimization in Young Women : A Randomized Controlled Study in Swedish Youth Health Centers
- 2020
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Ingår i: Journal of Interpersonal Violence. - : SAGE Publications. - 0886-2605 .- 1552-6518. ; 35:1-2, s. 77-99
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Tidskriftsartikel (refereegranskat)abstract
- Youth is a period in life when the risk of violence victimization is high and association between victimization and ill health is well established. Youth rarely reveal violence victimization to health professionals if not directly asked but favor health professionals asking about victimization. The study’s primary aim was to examine health outcomes in young women being routinely asked about violence victimization and offered subsequent support, compared with controls, at 12-month follow-up. Secondary aims were to examine to what extent routine inquiry altered the consultation and re-victimization rates during the study period. A randomized controlled intervention study was conducted at Swedish youth health centers. Participants assigned to the intervention group were asked structured questions about violence. Victimized participants received empowering strategies and were offered further counseling. Participants in the control group completed questionnaires about victimization after the visit. Both groups answered questions about sociodemographics and health, constructed from validated instruments. A questionnaire was administered to all participants 12 months after baseline. Of 1,445 eligible young women, 1,051 (73%) participated, with 54% of the participants completing the 12-month follow-up. Lifetime violence victimization was reported by 53% in the intervention group and 60% in the control group, ns. There were no significant differences in health outcomes, between baseline and 12-month follow-up, within either group or between groups. Re-victimization rates were 16% in the intervention group and 12% in the control group, ns. Of victimized young women in the intervention group, 14% wanted and received further counseling. Routine inquiry about violence victimization and empowering strategies were feasible within ordinary consultations at youth health centers but did not demonstrate improved health outcomes at 12-month follow-up compared with controls. Questions about violence led to a high degree of disclosure, and 14% of victimized young women in the intervention group received further counseling as a result.
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- Palm, Anna, et al.
(författare)
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Violence victimisation-a watershed for young womens mental and physical health
- 2016
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Ingår i: European Journal of Public Health. - : OXFORD UNIV PRESS. - 1101-1262 .- 1464-360X. ; 26:5, s. 861-867
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The association between victimisation and adverse health in children is well established but few studies have addressed the effect of victimisation, especially multiple victimisations, in older adolescents and young adults. The aim of this study was to assess self-reported health in young women (15-22 years) victimised to one or more types of violence, compared with non-victimised.aEuro integral Methods: Young women visiting youth health centres in Sweden answered a questionnaire constructed from standardised instruments addressing violence victimisation (emotional, physical, sexual and family violence), socio-demographics, substance use and physical and mental health. Adjusted odds ratio (AOR) with 95% confidence interval (CI) and attributable risk (AR) were assessed.aEuro integral Results: Of 1051 women (73% of eligible women), 25% were lifetime victims of one type of violence and 31% of two or more types of violence. Sexual-minority young women were more victimised than heterosexual women. Violence victimisation increased the risk for adverse health outcomes, especially evident for those multiply victimised. Victims of two or more types of violence had AOR 11.8 (CI 6.9-20.1) for post-traumatic stress symptoms, 6.3 (CI 3.9-10.2) for anxiety symptoms and 10.8 (CI 5.2-22.5) for suicide ideation. The AR of victimisation accounted for 41% of post-traumatic stress symptoms, 30% of anxiety symptoms and 27% of suicide ideation. Stratified analyses showed that lower economic resources did not influence health negatively for non-victimised, whereas it multiplicatively reinforced ill-health when combined with violence victimisation.aEuro integral Conclusion: Violence victimisation, and particularly multiple victimisations, was strongly associated with mental ill-health in young women, especially evident in those with low economic resources.
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