| 1. |
- Hao, Wende, et al.
(författare)
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Vitronectin : a promising breast cancer serum biomarker for early diagnosis of breast cancer in patients
- 2016
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Ingår i: Tumor Biology. - : Springer. - 1010-4283 .- 1423-0380. ; 37:7, s. 8909-8916
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Tidskriftsartikel (refereegranskat)abstract
- Breast cancer is the most common cancer in women worldwide, identification of new biomarkers for early diagnosis and detection will improve the clinical outcome of breast cancer patients. In the present study, we determined serum levels of vitronectin (VN) in 93 breast cancer patients, 30 benign breast lesions, 9 precancerous lesions, and 30 healthy individuals by enzyme-linked immunosorbent assays. Serum VN level was significantly higher in patients with stage 0-I primary breast cancer than in healthy individuals, patients with benign breast lesion or precancerous lesions, as well as those with breast cancer of higher stages. Serum VN level was significantly and negatively correlated with tumor size, lymph node status, and clinical stage (p < 0.05 in all cases). In addition, VN displayed higher area under curve (AUC) value (0.73, 95 % confidence interval (CI) [0.62-0.84]) than carcinoembryonic antigen (CEA) (0.64, 95 % CI [0.52-0.77]) and cancer antigen 15-3 (CA 15-3) (0.69, 95 % CI [0.58-0.81]) when used to distinguish stage 0-I cancer and normal control. Importantly, the combined use of three biomarkers yielded an improvement in receiver operating characteristic curve with an AUC of 0.83, 95 % CI [0.74-0.92]. Taken together, our current study showed for the first time that serum VN is a promising biomarker for early diagnosis of breast cancer when combined with CEA and CA15-3.
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| 2. |
- Fu, Hao, et al.
(författare)
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A compact real-time simulator with spatial-temporal parallel design for large-scale wind farms
- 2021
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Ingår i: CSEE Journal of Power and Energy Systems. - : Power System Technology Press. - 2096-0042. ; 9:1, s. 50-65
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Tidskriftsartikel (refereegranskat)abstract
- Real-time simulation of large-scale wind farms with detailed modelling can provide accurate insights into system transient behaviors, but entails challenges in computing resources. This paper develops a compact real-time simulator based on field programmable gate array (FPGA) for large-scale wind farms, in which the spatial-temporal parallel design method is proposed to address the huge computation resource demand associated with detailed modelling. The wind farm is decoupled into several subsystems based on model consistency, and the electrical system and control system of each subsystem are solved in parallel. Both module-level pipeline technique and superscalar pipeline technique are introduced to the wind farms' simulation to effectively improve the utilization of hardware resources. In Case Studies, real-time simulations of two modified wind farms are carried out on a single FPGA separately, including one with 13 permanent magnet synchronous generators under a time-step of 11 μβ, and the other with 30 squirrel-cage induction generators under a time-step of 8μβ. Simulation tests under different scenarios are implemented to validate the numerical performance of the real-time simulator, and a comparison with the commercial tool PSCAD/EMTDC demonstrates the accuracy and effectiveness of the proposed design.
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| 3. |
- Fu, Hao, et al.
(författare)
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Asynchronous multi-rate method of real-time simulation for active distribution networks
- 2023
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Ingår i: IET Renewable Power Generation. - : INST ENGINEERING TECHNOLOGY-IET. - 1752-1416 .- 1752-1424.
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Tidskriftsartikel (refereegranskat)abstract
- The real-time simulation of active distribution networks (ADNs) can provide an accurate insight into transient behaviours, but faces challenges in simulation efficiency and flexibility brought by larger system scales and wider time-scale ranges. This paper presents an asynchronous multi-rate (AMR) method and design for the real-time simulation of large-scale ADNs. In the proposed method, the entire ADN was decoupled into different subsystems according to accuracy requirements, and optimized time-steps were allocated to each subsystem to realize a fully distributed simulation. This not only alleviated the time-step coordination problem existing in multi-rate real-time simulations, but also enhanced the flexible expansion capabilities of the real-time simulator. To realize the AMR real-time simulation, a multi-rate interfacing method, synchronization mechanism, and data communication strategy are proposed in this paper, and their hardware design is also presented in detail. A modified IEEE 123-node system with photovoltaics and wind turbine generators was simulated on a 3 field-programmable gate arrays (FPGAs)-based AMR real-time simulator. The real-time results were captured by the oscilloscope and verified with PSCAD/EMTDC, which demonstrated the superiority in simulation flexibility and accuracy compared with the synchronous multi-rate (SMR) method.
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| 4. |
- Ouyang, Tianhong, et al.
(författare)
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Effect of defects on adsorption characteristics of AlN monolayer towards SO2 and NO2 : Ab initio exposure
- 2018
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Ingår i: Applied Surface Science. - : ELSEVIER SCIENCE BV. - 0169-4332 .- 1873-5584. ; 462, s. 615-622
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Tidskriftsartikel (refereegranskat)abstract
- Density functional theory (DFT) calculations have been employed to explore the adsorption properties of pristine and vacancy-defective AlN monolayer towards SO2 and NO2 in terms of their adsorption energies and electronic structures. The calculations with van der Waals effect are performed to study the binding mechanism of pristine and vacancy-defective AlN nanosheet with SO2 and NO2. Three types of vacancy defects are considered including Al-monovacancy, N-monovacancy and divacancy. The adsorption energies of vacancy-defective AlN monolayer towards SO2 and NO2 are found to be much higher than that of pristine nanosheet. The equilibrium adsorption sites and configurations of the gas molecules on AlN nanosheets are determined. The Bader charge transfer analysis reveals that a considerable amount of charge is transferred from the vacancy-defective AlN nanosheets to the gases leading to the increase of adsorption energies. The results of difference charge densities, band structures, electronic density of states and work function further give insight into adsorption energies. The dramatical changes of electronic band structures after gas interaction suggest the excellent adsorption properties of vacancy-defective AlN monolayer towards SO2 and NO2.
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| 5. |
- Zhang, Wei, et al.
(författare)
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Thermal detection of surface plasmons on gold nanohole arrays
- 2012
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Ingår i: Chinese Science Bulletin. - : Springer Science and Business Media LLC. - 1001-6538 .- 1861-9541. ; 57:1, s. 68-71
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Tidskriftsartikel (refereegranskat)abstract
- We used a thin-film thermocouple to detect the thermal effect of surface plasmons excited in Au nanohole array structures. We found that the thermal electromotive force of Au film with periodic nanohole structures is three times greater than that of a bare Au film for 785-nm laser excitation at a given power. This effect is caused by the resonant excitation of localized surface plasmons in the nanoholes. In addition, we found that the thermal electromotive force (EMF) of the Au film with dumbbell-like nanohole arrays depends strongly on the incident polarization. The thermal EMF is the greatest when the excitation light is polarized perpendicular to the long axis of the dumbbell.
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