| 1. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - 2050-084X. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 2. |
- Bentham, James, et al.
(författare)
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A century of trends in adult human height
- 2016
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Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
-
Tidskriftsartikel (refereegranskat)abstract
- Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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| 3. |
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| 4. |
- Hensher, David, et al.
(författare)
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Understanding MaaS: Past, Present and Future
- 2020
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Daily references to the changing landscape in the provision of passenger transport services is made in the transport literature, including grey material. Mobility as a Service (MaaS) is the acronym which appears to have caught the imagination of technology providers with promises of a new era of passenger transport whereby assets need not be owned and services can be bought at the point of need. It is the technological developments which have spearheaded the new understanding of MaaS. MaaS has evolved into a concept that integrates public and private transport services to provide one- stop access through a common interface. MaaS is at the centre of the popular view on future collaborative and connected mobility. For transport policy, MaaS is seen as a way to reduce car traffic, and its negative externalities, by enabling citizens to satisfy their mobility needs without having to own assets such as automobiles, either conventional or (in the future) self-driving. MaaS also opens new choices for non-car owning citizens who previously had limited transport options, making some of them socially excluded. Whilst definitions vary, the concept of MaaS has several dimensions: in the form of a smart app and in real-time, it provides mobility services using multimodal options, through a sophisticated journey planner that provides the user with multiple customised options and offers the opportunity for payment either at the point of use or with a pre-purchased mobility bundle. This single platform is envisaged to eventually be transferable around the world from city to city and region to region and also to remain pervasive to the user by working and monitoring the journey in real-time and providing options for recovery in the case of disruption, and with an aspiration to support public equity objectives. MaaS has also received considerable attention in recent years from decision-makers (for instance, the Finnish government has implemented new transport regulations intended to facilitate MaaS developments) and practitioners (examples of MaaS start-ups include MaaS Global in Finland, EC2B in Sweden and Moovel in Germany) as well as researchers (e.g., Hensher and Mulley (2019) Hensher, 2017; Jittrapirom, 2017; Sochor et al., 2016; Wong et al., 2019; Mulley, 2017). Still, the knowledge of MaaS is nascent, trials for the most part have not been thoroughly evaluated and the evidence for the mobility and societal benefits of MaaS have yet to be confirmed. The paper is structured as follows. The next section provides the literature context that underpins the part of the title of this paper relating to the ‘Past’. This is followed by a section detailing the present in terms of a current MaaS trial in Sydney, New South Wales, designed to provide another ‘data point’ in our current understanding of MaaS. The penultimate section looks to the future and the challenges ahead by identifying some key questions critical to the development of MaaS. The final section concludes.
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| 5. |
- Hensher, David, et al.
(författare)
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Understanding Mobility as a Service (MaaS): Past, Present and Future
- 2020
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- The widespread adoption of smartphones, ridesharing and carsharing have disrupted the transport sector. In cities around the world, new mobility services are both welcomed and challenged by regulators and incumbent operators. Mobility as a Service (MaaS), an ecosystem designed to deliver collaborative and connected mobility services in a society increasingly embracing a sharing culture, is at the center of this disruption. Understanding Mobility as a Service (MaaS): Past, Present and Future examines such topics as: - How likely MaaS will be implemented in one digital platform app - Whether MaaS will look the same in all countries - The role multi-modal contract brokers play - Mobility regulations and pricing models - MaaS trials, their impacts and consequences Written by the leading thinkers in the field for researchers, practitioners, and policy makers, Understanding Mobility as a Service (MaaS): Past, Present and Future serves as a single source on all the current and evolving developments, debates, and challenges.
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| 6. |
- Ngo, Son Tung, et al.
(författare)
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Distal Hydrophobic Loop Modulates the Copper Active Site and Reaction of AA13 Polysaccharide Monooxygenases
- 2022
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Ingår i: Journal of Physical Chemistry B. - : American Chemical Society (ACS). - 1520-6106 .- 1520-5207. ; 126:39, s. 7567-7578
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Tidskriftsartikel (refereegranskat)abstract
- Polysaccharide monooxygenases (PMOs) use a type-2 copper center to activate O2 for the selective hydroxylation of one of the two C-H bonds of glycosidic linkages. Our electron paramagnetic resonance (EPR) analysis and molecular dynamics (MD) simulations suggest the unprecedented dynamic roles of the loop containing the residue G89 (G89 loop) on the active site structure and reaction cycle of starch-active PMOs (AA13 PMOs). In the Cu(II) state, the G89 loop could switch between an open and closed conformation, which is associated with the binding and dissociation of an aqueous ligand in the distal site, respectively. The conformation of the G89 loop influences the positioning of the copper center on the preferred substrate of AA13 PMOs. The dissociation of the distal ligand results in the bending of the T-shaped core of the Cu(II) active site, which could help facilitate its reduction to the active Cu(I) state. In the Cu(I) state, the G89 loop is in the closed conformation with a confined copper center, which could allow for efficient O2 binding. In addition, the G89 loop remains in the closed conformation in the Cu(II)-superoxo intermediate, which could prevent off-pathway superoxide release via exchange with the distal aqueous ligand. Finally, at the end of the reaction cycle, aqueous ligand binding to the distal site could switch the G89 loop to the open conformation and facilitate product release.
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| 7. |
- Smith, Göran, 1988-, et al.
(författare)
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Mobility-as-a-Service users : insights from a trial in Sydney
- 2023
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Ingår i: European Transport Research Review. - : Springer. - 1867-0717 .- 1866-8887. ; 15
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Tidskriftsartikel (refereegranskat)abstract
- The positive effects that Mobility-as-a-Service (MaaS) is envisioned to have on transport can only be reaped if people are using MaaS. Yet, the understanding of the user perspective on MaaS is incomplete and primarily based on experiments with non-users. To address this shortcoming, this paper reports user experiences from a trial of a high-level MaaS service in Sydney, Australia. Based on questionnaires and interviews, it analyses who participated in the trial and why, and whether the trial experience satisfied their motives. The contribution to the literature on MaaS is three-fold. Firstly, most of the people that participated in the trial were frequent users of both public transport and private cars. This supports the notion that multi-modal travellers are likely early adopters of MaaS and contradicts the fear that MaaS does not appeal to private car users. Secondly, a desire to contribute to innovation and curiosity about MaaS were the main motives for signing up for the trial, which highlights the important role an inviting setting for experimentation, such as a trial, can play in stimulating MaaS adoption. Thirdly, many participants struggled with making the trialled service work for them and on average they seemed to value the support and feedback functions higher than other service features. This underscores the novelty of MaaS, compared to existing service models, and reiterates the notion that more than an app and a few subscription plans is needed to make MaaS useful for users.
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| 8. |
- Smith, Göran, 1988-, et al.
(författare)
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Workshop 5 report : New service models - Governing emerging mobility services
- 2024
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Ingår i: Research in Transportation Economics. - : Emerald Publishing. - 0739-8859 .- 1875-7979. ; 103
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Tidskriftsartikel (refereegranskat)abstract
- The rise of new service models for passenger transport is arguably transforming the mobility landscape. Concurrently, the COVID-19 pandemic has disrupted mobility practices and questioned traditional public transport models. Given the negative externalities of transport, and the key role of shared mobility in reducing these, it is therefore critical to work out what governments can do to ensure that the new service models contribute to making mobility service systems more attractive to users as well as more energy-, space- and cost-efficient. Workshop 5 of the 17th International Conference on Competition and Ownership in Land Passenger Transport set out to address these issues. It included thirteen papers that reported evidence about demand-responsive transport (DRT), ridesourcing, ridesharing, and Mobility-as-a-Service (MaaS) as well as about innovations within traditional public transport, taxi, and paratransit. The workshop discussed what roles governments have adopted, what types of regulations and policies they have been using, and what is known about the impacts of these governance approaches. Drawing on this discussion, the workshop developed a set of policy recommendations designed to cater for democratic governance processes with transformative impacts as well as a list of potential avenues for further research on the governance of emerging mobility services.
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| 9. |
- Son, Hoang Nghia, et al.
(författare)
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Effects of simulated microgravity on the morphology of mouse embryonic fibroblasts (MEFs)
- 2020
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Ingår i: Romanian Biotechnological Letters. - Bucharest : University of Bucharest. - 1224-5984 .- 2248-3942. ; 25:6, s. 2156-2160
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to assess the effects of simulated microgravity on mouse embryonic fibroblast (MEF) morphology. The results showed that the area of MEFs under simulated microgravity was 7843.39 +/- 551.31 mu m(2) which was lower than the control group (9832.72 +/- 453.86 mu m(2)) (p < 0.001). The nuclear area of MEFs under simulated microgravity (290.76 +/- 4.58 mu m(2)) and the control group (296.8 +/- 4.58 mu m(2)) did not statistically differ. In addition, the nuclear shape value of the MEFs under simulated microgravity and the control group did not statistically differ (0.86 +/- 0.006 vs. 0.87 +/- 0.003, respectively). The nuclear intensity of MEFs under simulated microgravity (19361 +/- 852) was higher than the control group (16997 +/- 285) (P <0.05). Moreover, the flow cytometry analysis indicated the reduced GO/G1 phase cell ratio and the increased S phase and G2/M phase cell ratio in MEFs under simulated microgravity. Simulated microgravity also induced a decrease in diameter of actin filament bundles of the MEFs under simulated microgravity (1.61 +/- 0.33 mu m) compared to the control group (1.79 +/- 0.32 mu m) (P <0.01). These results revealed that simulated microgravity is capable of inducing the morphological changes of mouse embryonic fibroblasts.
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