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Sökning: WFRF:(Hochberg Fred H)

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1.
  • Gardiner, Chris, et al. (författare)
  • Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.
  • 2015
  • Ingår i: Journal of Extracellular Vesicles. - : Wiley. - 2001-3078. ; 4:1
  • Forskningsöversikt (refereegranskat)abstract
    • Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor-bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.
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2.
  • Lötvall, Jan, 1956, et al. (författare)
  • Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.
  • 2014
  • Ingår i: Journal of extracellular vesicles. - : Wiley. - 2001-3078. ; 3
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Secreted membrane-enclosed vesicles, collectively called extracellular vesicles (EVs), which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and other EV subsets, encompass a very rapidly growing scientific field in biology and medicine. Importantly, it is currently technically challenging to obtain a totally pure EV fraction free from non-vesicular components for functional studies, and therefore there is a need to establish guidelines for analyses of these vesicles and reporting of scientific studies on EV biology. Here, the International Society for Extracellular Vesicles (ISEV) provides researchers with a minimal set of biochemical, biophysical and functional standards that should be used to attribute any specific biological cargo or functions to EVs.
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