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Sökning: WFRF:(Hochbergs Peter)

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1.
  • Békássy, Albert, et al. (författare)
  • Erwinase-induced pancreatitis
  • 1992
  • Ingår i: The Lancet. - 1474-547X. ; 340:8834-8835, s. 1552-1553
  • Tidskriftsartikel (refereegranskat)
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2.
  • El-Segaier, Milad, et al. (författare)
  • Late coronary complications after arterial switch operation and their treatment.
  • 2010
  • Ingår i: Catheterization and Cardiovascular Interventions. - : Wiley. - 1522-726X .- 1522-1946. ; 76, s. 1027-1032
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVES:: To report the late coronary complications and their treatment after ASO. BACKGROUND:: Asymptomatic patients after arterial switch operation (ASO) may have coronary ostial stenosis or obstruction. METHODS:: Since 1980, 279 patients were operated with ASO. At the time of preparing this article, selective follow-up coronary angiograms were done on 81 patients. RESULTS:: Coronary stenosis was found in six patients. A six year-old patient with left coronary artery (LCA) ostial stenosis and a nine year-old patient with conus branch occlusion had good collaterals without a need for further treatment. One patient with LCA obstruction, myocardial infarction, and left ventricular failure was operated with osteoplasty at age of 16 years. In three essentially asymptomatic patients stenting of LCA ostium stenosis was done: in two of them with drug-eluting stents at nine and ten years of age and in one with bare-metal stent at 18 years of age. One of these patients was earlier treated with balloon dilatation at five years of age which caused intimal dissection. CONCLUSIONS:: Asymptomatic patients with an uneventful course after ASO may have coronary obstruction. This necessitates follow-up coronary evaluation in all patients. Stenting of the coronary arteries is an option for treatment. (c) 2010 Wiley-Liss, Inc.
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4.
  • Hochbergs, Peter (författare)
  • Magnetic Resonance Imaging in Legg-Calvé-Perthes Disease
  • 1998
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The aims of this study were: to compare the cartilaginous outline of the femoral head obtained on arthrograms with those on MR images and to correlate it to the bony head outlines on conventional radiograps; to study early, postoperative cartilaginous and bony remodeling of the femoral head, after proximal femoral varus derotation extension osteotomy, with MR imaging and conventional radiography; to describe signal abnormalities on MR images in the femoral epiphysis, their location, extent and restitution over time; to evaluate the degree and persistence of synovitis in the hip joint by MR imaging; to analyze the metaphyseal histology and to correlate it to the signal intensity on the MR images in the corresponding biopsy region. Results and conclusions: MR imaging and arthrography define the shape of the femoral head cartilage equally well. The bony head outlines on conventional radiographs do not adequately reflect the cartilaginous outlines of the femoral head obtained by MR imaging. There is an early, postoperative, continuous, spherical remodeling following proximal femoral varus derotation extension osteotomy. The cartilaginous remodeling as seen in MR images appears earlier than the bony remodeling seen on conventional radiographs. In the coronal plane on MR images, the pathological signal is lowest in the central portion of the necrotic epiphysis. In addition, hips with advanced disease show signal changes in the peripheral regions. Repair processes start from the periphery, slowly progressing towards the center of the necrotic epiphyseal region. Signal changes persist in the period 3-6 years after diagnosis. All diseased hips have synovitis initially. The degree of synovitis on MR images in the inferomedial aspect of the hip joint correlates to the extent of the epiphyseal necrosis seen in conventional radiography or MR imaging. Synovitis is most intense initially in the disease, slowly decreasing, but persisting for several years, in some hips for more than 5 years after diagnosis. There is no correlation between the uniform histological patterns of consistent morphologic changes of the metaphysis and MR imaging with a low-field unit.
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5.
  • Holmqvist, Catarina, et al. (författare)
  • Collateral flow in coarctation of the aorta with magnetic resonance velocity mapping: correlation to morphological imaging of collateral vessels.
  • 2002
  • Ingår i: Journal of Magnetic Resonance Imaging. - : Wiley. - 1522-2586 .- 1053-1807. ; 15:1, s. 39-46
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: To correlate quantification of collateral flow in aortic coarctation with the morphological visualization of the collateral vessels and to compare different approaches to measurement of collateral flow. MATERIALS AND METHODS: Thirteen children with coarctation were examined with T1-weighted spin-echo (T1-W SE) imaging and 3D contrast-enhanced magnetic resonance angiography (MRA). MR velocity mapping was performed at four levels in the descending aorta. RESULTS: The flow immediately above and below the coarctation did not differ significantly. Measuring within the coarctation resulted in flow overestimation. The increase of flow from proximal to distal aorta was 12 +/- 21% in patients with no or uncertain collaterals and 69 +/- 55% in patients with pronounced collaterals. Spin-echo images and MRA were comparable in visualizing collateral vessels. The visual estimation of collaterals correlated reasonably well with flow quantification MR velocity mapping. CONCLUSION: Collateral flow assessment with MR velocity mapping is an accurate technique for evaluating the hemodynamic importance of a coarctation and is recommended if abundant collaterals are not visualized with spin echo or MRA.
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6.
  • Holmqvist, Catarina, et al. (författare)
  • Pre-operative evaluation with MR in tetralogy of fallot and pulmonary atresia with ventricular septal defect
  • 2001
  • Ingår i: Acta Radiologica. - : SAGE Publications. - 1600-0455 .- 0284-1851. ; 42:1, s. 63-69
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: To assess whether MR imaging could replace angiography in preoperative evaluation of patients with tetralogy of Fallot and pulmonary atresia with ventricular septal defect (VSD), especially since the surgical correction was done earlier than was previously the rule. MATERIAL AND METHODS: Fourteen patients with tetralogy of Fallot (n = 10) or pulmonary atresia with VSD (n = 4), mean age 7.5 +/- 4.4 months, were evaluated with angiocardiography and MR before definitive surgical correction. RESULTS: There was good diagnostic agreement between the two modalities when evaluating right ventricular outflow obstruction; 86% for valvular and 93% for supravalvular stenosis, but the agreement was somewhat lower for the subvalvular obstruction (57%). Surgery findings, however, were in favour of MR in 5 patients concerning the subvalvular right ventricular outflow tract obstruction. MR images identified all stenoses in the right and left pulmonary arteries, but overlooked one stenosis in the main pulmonary artery. MR could evaluate patency in all palliative shunts. CONCLUSION: Even in this young age group, MR imaging offers a good alternative to angiocardiography for the pre-operative evaluation of the right ventricular outflow tract, the main pulmonary artery and the proximal right and left pulmonary arteries, before definitive surgical correction of tetralogy of Fallot and pulmonary atresia with VSD.
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7.
  • Laurell, L, et al. (författare)
  • Capsular distance in the hip of the healthy child - normal values with sonography and MR imaging.
  • 2002
  • Ingår i: Acta Radiologica. - : SAGE Publications. - 1600-0455 .- 0284-1851. ; 43:2, s. 213-216
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: To determine the normal values of the anterior and posterior capsular distances of the hip joint in healthy children by means of US, using MR imaging as reference, and to evaluate any possible correlation between age, length, weight and anterior capsular distance (ACD). MATERIAL AND METHODS: In our first study both hips in 14 healthy children (5-18 years old) were examined with US and MR to obtain measurements of the ACD and the posterior capsular distance (PCD). The distance from the anterior or posterior aspect of the femoral neck to the anterior or posterior aspect, respectively, of the outer limit of the capsule was determined. The distances were measured both with the hips in spontaneous external rotation of 10-15 degrees and in internal rotation of 45 degrees. In our second study, both hips in 28 healthy children (3-16 years old) were examined with US to determine the ACD. Age, length and weight were recorded. RESULTS: Study I: There was good correlation between the US and MR measurements in all positions. The ACD measured by US was significantly increased in inward rotation of the hip. Study II: There was no correlation between ACD and age, length or weight. CONCLUSION: The PCD of the hip joint can be accurately measured by US with the hip in internal rotation of 45 degrees. When compared with MR values, the ACD measured by US was dependent on the degree of rotation of the leg and increased significantly in internal rotation. Because the outer limit of the external layer of the joint capsule is sonographically more distinct, we suggest that the capsular distance should be measured from the outer limit of the joint capsule to the anterior or posterior aspect of the femoral neck. The measurement should be made perpendicular to the femoral neck, at the position where the greatest numerical value is obtained.
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8.
  • Lyttkens, Kerstin, et al. (författare)
  • Evaluation of the image quality of ink-jet printed paper copies of digital chest radiographs as compared with film : A receiver operating characteristic study
  • 1994
  • Ingår i: Journal of Digital Imaging. - 0897-1889. ; 7:2, s. 61-68
  • Tidskriftsartikel (refereegranskat)abstract
    • Paper copies of digital radiographs printed with the continuous ink-jet technique have proved to be of a high enough quality for demonstration purposes. We present a study on the image quality of ink-jet printed paper copies of digital chest radiographs, based on receiver operating characteristic (ROC) analysis. Eighty-three digital radiographs of a chest phatom with simulated tumors in the mediastinum and right lund, derived from a computed radiography (CR) system were presented in two series of hard copies as ink-jet printed paper copies and as laser recorded film. The images, with a matrix of 1,760×2,140 pixels, were printed with a spatial resolution of 10 pixels/mm in the CR film recorder as well as in the ink-jet printer. On film, every image was recorded in two versions, one optimized for the mediastinum and one for the lungs. On paper, only one image was printed; this constituted an effort to optimize both the mediastinum and the lungs. The ink-jet printed images, printed on a matt coated paper, were viewed as on-sight images with reflected light. The exdaminations were reviewed by six radiologists, and ROC curves were constructed. No significant difference was found between the performance of film and that of ink-jet paper prints. Because the cost for a paper copy is only a tenth of that of film, remarkable cost reductions can be achieved by using the ink jet technique instead. Our results show that further quality studies of ink-jet printed images are worthwhile.
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9.
  • Pesonen, Erkki, et al. (författare)
  • Right coronary fistula and aneurysm draining to the right atrium.
  • 2009
  • Ingår i: Acta paediatrica. - : Wiley. - 1651-2227 .- 0803-5253. ; 98, s. 1530-1531
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract In a 3-year-old boy, a continuous heart murmur was heard. The echocardiogram showed a dilated right coronary artery suggesting the existence of a coronary fistula. A more detailed echocardiogram when the patient was sedated revealed a fistula leading to a large aneurysm and further to the right atrium. The accidental dissection and thrombosis during the interventional heart catheterization resulted in a closure of the fistula. A continuous heart murmur and a dilated coronary artery are the hallmarks of coronary fistula. Conclusion: Anatomic details of coronary fistula might be possible to see in an echocardiogram. Interventional heart catheterization is usually an adequate treatment option.
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10.
  • Stephensen, Sigurdur S., et al. (författare)
  • Changes in blood volume shunting in patients with atrial septal defects : Assessment of heart function with cardiovascular magnetic resonance during dobutamine stress
  • 2017
  • Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 18:10, s. 1145-1152
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The purpose of this study was to determine the effect of stress on left-to-right shunting in patients with atrial septal defect (ASD) and to investigate if the degree of shunting, cardiac output (CO), and right ventricular (RV) volumes are related to exercise capacity. Methods: Twenty-six patients with a secundum ASD and 16 healthy volunteers were studied with rest/stress cardiac magnetic resonance using 20 μg/kg/min dobutamine and 0.25-0.75 mg atropine to quantify CO, pulmonary to systemic flow ratio (QP/QS), and left ventricular (LV) and RV volumes. Peak oxygen uptake (VO2 peak) was determined on ergospirometry. Results: In patients with ASD the QP/QS decreased from 2.0 ± 0.2 at rest to 1.5 ± 0.1 (P < 0.001) during dobutamine stress (n = 20) and shunt volume per heartbeat decreased from 70 ± 9 to 38 ± 9 mL (P < 0.001). However, absolute shunt volume per minute was unchanged (5.1 ± 0.8 vs. 4.5 ± 1.0 L/min, P = 0.32) explained by a higher increase in systemic CO during stress (90 ± 11%) compared with pulmonary CO (43 ± 7%, P < 0.001). In ASD patients, VO2 peak correlated with aortic CO during stress (r = 0.77) and QP/QS at rest (r = -0.48) but not during stress (P = 0.09). VO2 peak did not correlate with RV volumes in patients. Conclusion: Pulmonary to systemic flow ratio and shunt volume per heartbeat decrease during stress in ASD patients. This may be explained by an enhanced LV diastolic function during stress and may have implications to detect disturbances in LV compliance in ASD patients. A high systemic CO during stress is a strong predictor of exercise capacity.
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