| 1. |
- Watson, Hunna J., et al.
(författare)
-
Common Genetic Variation and Age of Onset of Anorexia Nervosa
- 2022
-
Ingår i: BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE. - : Elsevier BV. - 2667-1743. ; 2:4, s. 368-378
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Genetics and biology may influence the age of onset of anorexia nervosa (AN). The aims of this study were to determine whether common genetic variation contributes to age of onset of AN and to investigate the genetic associations between age of onset of AN and age at menarche.METHODS: A secondary analysis of the Psychiatric Genomics Consortium genome-wide association study (GWAS) of AN was performed, which included 9335 cases and 31,981 screened controls, all from European ancestries. We conducted GWASs of age of onset, early-onset AN (,13 years), and typical-onset AN, and genetic correlation, genetic risk score, and Mendelian randomization analyses.RESULTS: Two loci were genome-wide significant in the typical-onset AN GWAS. Heritability estimates (single nucleotide polymorphism-h2) were 0.01-0.04 for age of onset, 0.16-0.25 for early-onset AN, and 0.17-0.25 for typical-onset AN. Early-and typical-onset AN showed distinct genetic correlation patterns with putative risk factors for AN. Specifically, early-onset AN was significantly genetically correlated with younger age at menarche, and typical-onset AN was significantly negatively genetically correlated with anthropometric traits. Genetic risk scores for age of onset and early-onset AN estimated from independent GWASs significantly predicted age of onset. Mendelian randomization analysis suggested a causal link between younger age at menarche and early -onset AN.CONCLUSIONS: Our results provide evidence consistent with a common variant genetic basis for age of onset and implicate biological pathways regulating menarche and reproduction.
|
|
| 2. |
- Gorska, M., et al.
(författare)
-
Nuclear Structure far off Stability - RISING Campaigns
- 2007
-
Ingår i: Acta Physica Polonica. Series B: Elementary Particle Physics, Nuclear Physics, Statistical Physics, Theory of Relativity, Field Theory. - 0587-4254. ; 38:4, s. 1219-1228
-
Tidskriftsartikel (refereegranskat)abstract
- Nuclear structure studies at CST attracted recently increased interest for the results of present activities as well as for the future project FAIR. A broad range of physics phenomena can be addressed by high-resolution in-beam gamma-ray spectroscopy experiments with radioactive beams offered within the Rare Isotopes Spectroscopic INvestigation at GSI (RISING) project. It combined the EUROBALL Ge-Cluster detectors, the MINIBALL Ce detectors, the HECTOR-BaF detectors, and the fragment separator FRS. The secondary beams produced at relativistic energies were used for Coulomb excitation or secondary fragmentation experiments to study projectile like nuclei by measuring de-excitation photons. The first results of the "fast beam campaign" is discussed in comparison to various shell model calculations. The discussion focuses on the N = 32, 34 sub-shell closure based on neutron rich Cr isotopes. Alternatively, the relativistic radioactive beams, both in their ground and isomeric states, were implanted and their decay could be investigated. The "stopped beam campaign" has started in October 2005 with a series of g-factor measurements. It continued from February 2006 with the next, configuration and the main goal of identification of new isomers and angular momentum population in fragmentation reactions.
|
|
| 3. |
- Al-Khatib, A, et al.
(författare)
-
Transition to non-collective states at high spin in Xe-124
- 2008
-
Ingår i: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 36:1, s. 21-29
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in Xe-124 were populated in the reaction Se-82(Ca-48, 6n) Xe-124 and gamma-ray coincidence relationships were measured with the Gammasphere spectrometer. Two new bands are observed and several of the previously known bands are extended in the high-as well as in the low-spin region. Two irregular high-spin structures are also added. The irregularities are a fingerprint of a transition from collective to non-collective behaviour. Configuration assignments to the new structures are proposed on the basis of systematics and by comparing experimental properties with calculations within the framework of the cranking model.
|
|
| 4. |
- Schwerdtfeger, W, et al.
(författare)
-
Shape Coexistence Near Neutron Number N=20 : First Identification of the E0 Decay from the Deformed First Excited J(pi)=0(+) State in Mg-30
- 2009
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 103:1, s. 012501-
-
Tidskriftsartikel (refereegranskat)abstract
- The 1789 keV state in Mg-30 was identified as the first excited 0(+) state via its electric monopole (E0) transition to the ground state. The measured small value of rho(2)(E0,0(2)(+)-> 0(1)(+))=(26.2 +/- 7.5)x10(-3) implies within a two-level model a small mixing of competing configurations with largely different intrinsic quadrupole deformation near the neutron shell closure at N=20. Axially symmetric configuration mixing calculations identify the ground state of Mg-30 to be based on neutron configurations below the N=20 shell closure, while the excited 0(+) state mainly consists of two neutrons excited into the nu 1f(7/2) orbital. The experimental result represents the first case where an E0 back decay from a strongly deformed second to the normal deformed first nuclear potential minimum well has been unambiguously identified, thus directly proving shape coexistence at the borderline of the much-debated "island of inversion."
|
|
| 5. |
- Singh, Purnima, et al.
(författare)
-
Highly deformed high-spin band in I-125
- 2011
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 84:2
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in I-125 have been investigated using the reaction Se-82(Ca-48, p4n) at a beam energy of 200 MeV and gamma-ray coincidence events were detected using the Gammasphere spectrometer. A deformed rotational band, extending up to I-pi = 95/2(-), was observed for the first time in a heavier odd-A iodine nucleus. The characteristics of the band are very similar to those of the highly deformed bands observed recently in neighboring nuclei and it is essentially identical to one of the previously known bands in Xe-126. The experimental results are compared to cranked Nilsson-Strutinsky calculations and possible configurations for the band are discussed.
|
|
| 6. |
- Singh, Purnima, et al.
(författare)
-
Noncollective aligned and antialigned states in I-125
- 2010
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 82:3
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in I-125 were populated using the reaction Se-82(Ca-48, p4n) at a beam energy of 200 MeV and gamma-ray coincidence events were acquired with the Gammasphere spectrometer. The level scheme of I-125 was extended considerably. In particular, maximally aligned states involving all eleven particles outside the Sn-114 core were observed. Comparison with cranked Nilsson-Strutinsky calculations suggests that three of these states are the final I-max states in terminating bands with all spin vectors aligned along a common axis. In two of these, one spin vector is antialigned and points in the opposite direction. In one of the states two spin vectors are antialigned. This is the first observation of a state with such a structure.
|
|
| 7. |
- Bhowal, S., et al.
(författare)
-
Development of collective structures over noncollective excitations in Nd-139
- 2011
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 84:2
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Nd-139 were investigated using the reaction Zr-96(Ca-48,5n) at a beam energy of 195 MeV and gamma-ray coincidences were acquired with the Euroball spectrometer. Apart from several dipole bands at medium excitation energy, three quadrupole bands have been observed at high spin. Linking transitions connecting two of the high-spin bands to low-energy states have been observed. Calculations based on the cranked-Nilsson-Strutinsky formalism have been used to assign configurations for the high-spin quadrupole bands.
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
- Leguillon, R., et al.
(författare)
-
High-spin spectroscopy of Nd-140
- 2013
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 88:1
-
Tidskriftsartikel (refereegranskat)abstract
- The population of the high-spin states in Nd-140 was investigated using the reaction Zr-96(Ca-48,4n). The results from two experiments, one with the EUROBALL array and one with the JUROGAM II + RITU + GREAT setup employing the recoil decay tagging technique, have been combined to develop a very detailed level scheme for Nd-140. Twelve bands of quadrupole transitions and eleven bands of dipole transitions were identified and their connections to low-lying states were established. Calculations using the cranked Nilsson-Strutinsky and the tilted axis cranking models were used to interpret the observed structures. The overall good agreement between the experimental results and the calculations assuming a triaxial shape of the nucleus strongly support the existence of a stable triaxial shape at high spins in this mass region.
|
|
| 11. |
- Nag, Somnath, et al.
(författare)
-
Collective and noncollective excitations in Te-122
- 2013
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 88:4
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in Te-122 were populated in the reaction Se-82(Ca-48, alpha 4n) Te-122 at a beam energy of 200 MeV and gamma-ray coincidences weremeasured with the Gammasphere spectrometer. The previously known level scheme was extended to considerably higher spin. Maximally aligned states and several high-energy transitions feeding into some of these levels were observed. In addition, seven collective high-spin bands were discovered for the first time in this nucleus. The experimental results are compared with cranked Nilsson-Strutinsky model calculations and possible configuration assignments to the new high-spin structures are discussed.
|
|
| 12. |
- Nag, Somnath, et al.
(författare)
-
Collective and noncollective states in (120)Te
- 2012
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 85:1
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in (120)Te were populated in the reaction (80)Se((48)Ca, alpha 4n)(120)Te at a beam energy of 207 MeV and gamma-ray coincidences were measured using the Gammasphere spectrometer. The previously known level scheme is extended to higher spin and new interband transitions and side-feeding branches are established. Five highly deformed rotational bands, extending up to almost I = 50, are observed for the first time. The bands are compared with similar structures found recently in neighboring nuclei. The experimental results are interpreted within the framework of the cranked Nilsson-Strutinsky model. Configuration assignments to several terminating states and to the high-spin bands are discussed.
|
|
| 13. |
- Nag, Somnath, et al.
(författare)
-
Revised level structure of Te-120
- 2014
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 90:3
-
Tidskriftsartikel (refereegranskat)abstract
- The level scheme of the nucleus Te-120, populated in the reaction Se-80(Ca-48, alpha 4n), was reinvestigated using gamma-ray coincidence data measured with the Gammasphere spectrometer. Previously, five high-spin rotational bands were discovered in this nucleus. The present reinvestigation revealed that the decay of band b1 is more complex than suggested in the earlier work and that it cannot be uniquely determined. Furthermore, a number of new transitions are added to the level scheme. The implications for the spin assignments and excitation energies of the five bands and for comparisons with cranked Nilsson-Strutinsky calculations are discussed.
|
|
| 14. |
- Petrache, C. M., et al.
(författare)
-
Triaxiality at high spins in Nd nuclei
- 2006
-
Ingår i: Physica Scripta. - 0031-8949. ; T125, s. 212-213
-
Tidskriftsartikel (refereegranskat)abstract
- The level structure of Nd-140(80) has been established up to spin 48 by in-beam gamma-ray spectroscopy using the Zr-96(Ca-48, 4n) reaction. High-fold gamma-ray coincidences were measured with the EUROBALL spectrometer. Twelve new rotational bands have been discovered at high spins, showing the change from a spherical single-particle behaviour at low spins to a deformed regime with stable triaxiality at high spins. Possible configurations are assigned to the observed bands on the basis of configuration-dependent cranked Nilsson-Strutinsky calculations.
|
|
| 15. |
- Singh, Purnima, et al.
(författare)
-
Core excitations beyond maximally aligned configurations in I-123
- 2012
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 85:3
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in I-123 have been populated in the Se-80(Ca-48, p4n) I-123 reaction at 207 MeV and gamma-ray coincidence events have been recorded with the Gammasphere spectrometer. The level scheme of I-123 has been extended up to spin I = 63/2. The nucleus undergoes a shape transition from moderately deformed states with collective rotation at low spins to noncollective oblate configurations at higher spins. Maximally aligned terminating states involving all nine particles outside the Sn-114 core and states with one particle antialigned are identified. A large number of weak transitions feed the terminating states. Cranked Nilsson-Strutinsky calculations have been performed to determine possible configurations for the observed energy levels.
|
|
| 16. |
- Singh, Purnima, et al.
(författare)
-
High-spin rotational bands in I-123
- 2012
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 86:6
-
Tidskriftsartikel (refereegranskat)abstract
- High-spin states in I-123 were populated in the reaction Se-80(Ca-48,p4n)I-123 at a beam energy of 207 MeV and gamma-ray coincidence events were measured using the Gammasphere spectrometer. Three weakly populated, high-spin rotational bands have been discovered with characteristics similar to those of the long collective bands recently observed in other nuclei of this mass region. Configuration assignments are proposed based on calculations within the framework of the cranked Nilsson-Strutinsky approach. DOI: 10.1103/PhysRevC.86.067305
|
|
| 17. |
- Zerrouki, T., et al.
(författare)
-
Shape evolution and magnetic rotation in Nd-141
- 2015
-
Ingår i: European Physical Journal A. Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 1434-6001. ; 51:4
-
Tidskriftsartikel (refereegranskat)abstract
- The high-spin states in Nd-141 were investigated using the Zr-96(Ca-48, 3n) reaction and the EU-ROBALL array. The level scheme has been extended up to an excitation energy of around 16MeV and spin 81/2. Two new bands of dipole transitions and three bands presumably of quadrupole transitions were identified and their connections to low-lying states were established. Cranked Nilsson-Strutinsky and tilted axis cranking calculations are combined in the interpretation of the observed dipole bands. The high-spin bands with assigned quadrupole transitions are interpreted as triaxial bands, while the dipole bands appear in the calculations to exhibit a shape evolution from low-deformation triaxial to spherical shape. They can be classified as magnetic rotation, with transition probabilities that show the characteristic decrease with angular momentum caused by the shears mechanism.
|
|
