| 1. |
- Fromell, Karin, et al.
(författare)
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A particulate platform for bioluminescent immunosensing
- 2007
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Ingår i: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 79:22, s. 8601-8607
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Tidskriftsartikel (refereegranskat)abstract
- The present study examines pyruvate kinase-conjugated antibodies for potential use in EUSA applications. The conjugates had an acceptable stability, and the coupling inflicted only minor impairment on the kinase activity. To mimic the setup of an immunoassay under development, a test antigen (BSA) was attached to polystyrene nanoparticles. This arrangement was found to be suitable as solid support for presentation of antigens in sensitive bioluminescence assays. The nanoparticles were well characterized in terms of protein surface load and were used to establish the number of conjugate complexes needed to generate a detectable signal. Under the biochemical conditions employed here, the detection limit of the pyruvate kinase conjugate lies in the femtomole range.
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| 2. |
- Kuzmin, Leonid, 1946, et al.
(författare)
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Single Photon Counter Based on a Josephson Junction at 14 GHz for Searching Galactic Axions
- 2018
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Ingår i: IEEE Transactions on Applied Superconductivity. - 1558-2515 .- 1051-8223. ; 28:7
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Tidskriftsartikel (refereegranskat)abstract
- Axions and axion-like particles appear in well-motivated extensions of the standard model of particle physics and may be the solution to the long-standing puzzle of the dark matter in our Universe. Several new experiments are foreseen in the next decade searching them in a wide range of the parameter space. In the mass region from few to several tens of microelectronvolt, detector sensitivity will be limited by the standard quantum limit of linear amplifiers and a new class of single microwave-photon detector will be needed. We have developed a single photon counter based on the voltage switching of an underdamped Josephson junction that is coupled to a coplanar waveguide. By measuring the switching voltage, we can register single photons at 14 GHz with the rate less than 1 photon per 3000 s.
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| 3. |
- Weitzel, Alexander, et al.
(författare)
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Sharpness of the Berezinskii-Kosterlitz-Thouless Transition in Disordered NbN Films
- 2023
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 131:8
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Tidskriftsartikel (refereegranskat)abstract
- We present a comprehensive investigation of the Berezinskii-Kosterlitz-Thouless transition in ultrathin strongly disordered NbN films. Measurements of resistance, current-voltage characteristics, and kinetic inductance on the very same device reveal a consistent picture of a sharp unbinding transition of vortex-antivortex pairs that fit standard renormalization group theory without extra assumptions in terms of inhomogeneity. Our experiments demonstrate that the previously observed broadening of the transition is not an intrinsic feature of strongly disordered superconductors and provide a clean starting point for the study of dynamical effects at the Berezinskii-Kosterlitz-Thouless transition.
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