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- Glimelius, B, et al.
(författare)
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Surgical management of rectal cancer
- 1996
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Ingår i: The British journal of surgery. - : Oxford University Press (OUP). - 0007-1323 .- 1365-2168. ; 83, s. 869-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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- Isacsson, G., et al.
(författare)
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Antidepressant medication prevents suicide in depression
- 2010
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 122:6, s. 454-460
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Ecological studies have demonstrated a substantial decrease in suicide in parallel with an increasing use of antidepressants. To investigate on the individual level the hypothesis that antidepressant medication was a causal factor. Method: Data on the toxicological detection of antidepressants in 18 922 suicides in Sweden 1992-2003 were linked to registers of psychiatric hospitalization as well as registers with sociodemographic data. Results: The probability for the toxicological detection of an antidepressant was lowest in the non-suicide controls, higher in suicides, and even higher in suicides that had been psychiatric inpatients but excluding those who had been in-patients for the treatment of depression. Conclusion: The finding that in-patient care for depression did not increase the probability of the detection of antidepressants in suicides is difficult to explain other than by the assumption that a substantial number of depressed individuals were saved from suicide by postdischarge treatment with antidepressant medication.
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- ISACSSON, G, et al.
(författare)
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Antidepressants and suicide
- 1995
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Ingår i: BMJ (Clinical research ed.). - : BMJ. - 0959-8138 .- 1468-5833. ; 310:6972, s. 127-127
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 21. |
- Isacsson, G, et al.
(författare)
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Antidepressants and suicide prevention
- 1996
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Ingår i: The American journal of psychiatry. - : American Psychiatric Association Publishing. - 0002-953X .- 1535-7228. ; 153:12, s. 1659-1659
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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- Isacsson, G., et al.
(författare)
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Decrease in suicide among the individuals treated with antidepressants: a controlled study of antidepressants in suicide, Sweden 1995-2005
- 2009
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 120:1, s. 37-44
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Ecological studies have demonstrated a substantial decrease in suicide in parallel with an increase in the use of antidepressants. Causality cannot, however, be inferred from such studies. The aim of this study was to test on the individual level the hypothesis that treatment with antidepressant medication has been a substantially contributing cause of the decrease in suicide. Method: Time trends in the detection of antidepressants and five control medications in the forensic toxicological screening of 16 937 suicides and 33 426 controls in Sweden 1995-2005. Results: The expected number of antidepressant-positive suicides in 2005 was 409 if the hypothesis was true and 603 if it was false. The observed number in 2005 was 420. The control medications were detected to the extent that was expected if not preventing suicide. Conclusion: The observed trend in the number of suicides with antidepressants was well predicted by the hypothesis that the increased use of antidepressants has been a substantially contributing cause of the decrease in suicide.
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- Isacsson, G, et al.
(författare)
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Psychotropics and suicide prevention.
- 1999
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Ingår i: British Journal of Psychiatry. - 0007-1250 .- 1472-1465. ; 174, s. 259-265
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Tidskriftsartikel (refereegranskat)
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| 29. |
- Isacsson, G, et al.
(författare)
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Psychotropics and suicide prevention. Implications from toxicological screening of 5281 suicides in Sweden 1992-1994
- 1999
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Ingår i: The British journal of psychiatry : the journal of mental science. - : Royal College of Psychiatrists. - 0007-1250. ; 174, s. 259-265
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Tidskriftsartikel (refereegranskat)abstract
- Systematic clinical investigations of consecutive suicides have found psychiatric disorders in 90–95% of subjects (depressive disorder 30–87%).AimsTo investigate use of psychotropics in men and women of different ages who commit suicide.MethodResults of toxicological screening in 5281 suicides in Sweden 1992–94 were studied.ResultsPsychotropics were detected in 45.3% of the suicides. Antidepressants were detected in 12.4% of the men and 26.2% of the women (7.2% and 14.2%, respectively, of those under 30 years of age). Neuroleptics or antiepileptics (in the absence of antidepressants) were detected in 8.3%, and anxiolytics/hypnotics alone in 20.5% of the subjects. Overdose by an antidepressant was the probable cause of death in 2.1% of the men and 7.9% of the women.ConclusionsThe pattern of psychotropics detected in toxicology was incongruent with the pattern of diagnoses found in the clinical investigations of suicides mentioned above. Depression appears to be undertreated in individuals committing suicide, especially in men and in subjects under 30 years of age.
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| 30. |
- Isacsson, G, et al.
(författare)
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Risks with citalopram in perspective
- 1996
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Ingår i: Lancet (London, England). - 0140-6736. ; 348:9033, s. 1033-1033
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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