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Sökning: WFRF:(Jakobsson Björn)

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1.
  • Jakobsson, Sofie, 1968, et al. (författare)
  • Health status and most distressing concerns at admission and discharge reported by patients cared for at an internal medical care ward
  • 2018
  • Ingår i: Scandinavian Journal of Caring Sciences. - : Wiley. - 0283-9318. ; 32:3, s. 1168-1178
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundTo promote patients' ability to regain health during hospitalisation, care should not only focus on disease but also on how patients perceive health. There is a lack of studies on how patients admitted for inpatients care perceive their health. AimTo investigate self-reported health at admission and discharge perceived by patients admitted to an internal medicine ward; and, further, to explore the most distressing concerns at admission and discharge and the factors that influence low health status at discharge. Designs and methodsOne hundred and forty-seven patients completed EQ-5D and an open-ended question What concerns distress you the most?' at admission and discharge. Descriptive, parametric and nonparametric analyses were used. Subset analyses were performed between three groups based on health change. Factors influencing low health status at discharge were tested in a logistic regression. To analyse most distressing concerns, an inductive content analysis was performed. ResultsThere was a significant increase in self-rated health for patients with gastrointestinal disorders. At discharge, 50% was identified with improved and 30% with unaltered health. Twenty per cent reported a significant deterioration of health and had the highest frequency of severe problems in all EQ-5D dimensions. Several patients left hospital with distressing symptoms, uncertainty and concerns that had persisted throughout their hospitalisation. Vulnerable patients were characterised by an acute admission, unemployment and longer hospitalisation. Low EQ VAS at admission predicted poor health at discharge. ConclusionsMany patients had low health status at admission. For some, this did not improve during hospital stay, and for some, it got worse. Our findings highlight a group, whose care can be improved, through information, support and follow-up routines within and outside the hospital. Identifying these patients, efforts to better support patients in their self-care, including relief of pain and worries, at discharge can be established.
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2.
  • Jakobsson, Sofie, 1968, et al. (författare)
  • Patient safety before and after implementing person-centred inpatient care - A quasi-experimental study.
  • 2020
  • Ingår i: Journal of clinical nursing. - : Wiley. - 1365-2702 .- 0962-1067. ; 29:3-4, s. 602-612
  • Tidskriftsartikel (refereegranskat)abstract
    • To evaluate aspects of patient safety before and after a person-centred (PC) inpatient care intervention.Transitioning from disease-centred to person-centred care requires great effort but can improve patient safety.A quasi-experimental study with data collection preceding and 12months after a PC inpatient care intervention.The study consecutively recruited adult patients (2014, n=263; 2015/2016, n=221) admitted to an inpatient care unit. The patients reported experiences of care at discharge and their perceived pain at admission and discharge. Medical records were reviewed to gather data on medications, planned care and clinical observations. The study is reported according to TREND guidelines.At discharge, patients receiving PC inpatient care reported competent medical-technical care. Patients receiving PC inpatient care reported more effective pain relief. Updated prescribed medications at the ward were maintained, and patients were made aware of planned medical care to higher extent during PC inpatient care. The assessment of pulse and body temperature was maintained, but fewer elective care patients had their blood pressure taken during PC inpatient care. Weight assessment was not prioritised during usual or PC inpatient care.Patients receiving PC inpatient care reported that they were given the best possible care and had less pain at discharge. The PC inpatient care included improved documentation and communication of planned medical care to the patients. Vital signs were more frequently recorded for patients admitted for acute care than patients admitted for elective care. PC inpatient care had no effect on frequency of weight measurements.PC inpatient care seems beneficial for the patients. Aspects of patient safety such as prescribed medications were maintained, and PC inpatient care seems to enhance the continuity of care. Inpatient clinical observations need further evaluation as healthcare transitions from disease-centred to person-centred care.
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3.
  • Jakobsson, Sofie, 1968, et al. (författare)
  • Person-centred inpatient care - A quasi-experimental study in an internal medicine context.
  • 2019
  • Ingår i: Journal of advanced nursing. - : Wiley. - 1365-2648 .- 0309-2402. ; 75:8, s. 1678-1689
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to evaluate effects of person-centred inpatient care on care processes in terms of satisfaction with care and person-centred content in medical records, and to evaluate effects on self-reported health and self-efficacy.Internal medicine inpatient care is complex, covering patients varying in age, medical conditions, health status, and other aspects. There has been limited research on the impact of person-centred care (PCC) on satisfaction with care and health outcomes in internal medicine care environments regardless of diagnosis and care pathway.A quasi-experimental study with pre- and postmeasurements.Adult patients admitted to an internal medicine inpatient unit were consecutively included over 16weeks in 2014 and 24weeks in 2015-2016. Data were collected before a person-centred inpatient care intervention (N=204) and 12months after the intervention was implemented (N=177). Data on satisfaction with care and self-reported health were collected at discharge and medical records were reviewed. The intervention included systematically applied person-centred assessment, health plans, and persistent PCC.After the intervention, patients rated higher satisfaction with care regarding essential components of PCC and more patients had received effective pain relief. There were no differences in information on self-care or medications, self-rated health, or self-efficacy.Care focused on the foundations of person-centredness seems to enhance both patients' perceptions of satisfaction and symptom management. Situational aspects such as care pathways should be considered when implementing person-centred inpatient care.CLINICALTRIALS.NCT03725813.
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4.
  • Reifarth, R., et al. (författare)
  • Nuclear astrophysics with radioactive ions at FAIR
  • 2016
  • Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
  • Konferensbidrag (refereegranskat)abstract
    • The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
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5.
  • Adler, Jan-Olof, et al. (författare)
  • The upgraded photon tagging facility at the MAX IV Laboratory
  • 2013
  • Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - : Elsevier BV. - 0167-5087 .- 0168-9002. ; 715, s. 1-10
  • Tidskriftsartikel (refereegranskat)abstract
    • A description is given of the upgraded photon tagging facility at the MAX IV Laboratory. Two magnetic spectrometers are used to momentum analyze post-bremsstrahlung electrons. The tagged photon range extends from 10 to 180 MeV with an energy resolution of about 300 keV. The system has been operated at rates up to 4 x 10(6) photons s(-1) MeV (-1). Different diagnostic tools are described as well as the experimental program.
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6.
  • Altstadt, S.G., et al. (författare)
  • B-13,B-14(n,gamma) via Coulomb Dissociation for Nucleosynthesis towards the r-Process
  • 2014
  • Ingår i: Nuclear Data Sheets. - : Elsevier BV. - 1095-9904 .- 0090-3752. ; 120, s. 197-200
  • Konferensbidrag (refereegranskat)abstract
    • Radioactive beams of 14,15B produced by fragmentation of a primary 40Ar beam were directed onto a Pb target to investigate the neutron breakup within the Coulomb field. The experiment was performed at the LAND/R3B setup. Preliminary results for the Coulomb dissociation cross sections as well as for the astrophysically interesting inverse reactions, 13,14B(n,γ), are presented.
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7.
  • Andersson, Björn O, 1982, et al. (författare)
  • A Modified TAB Model for Simulation of Atomization in Rotary Bell Spray Painting
  • 2013
  • Ingår i: Journal of Mechanical Engineering and Automation. - 2163-2413. ; 3:2, s. 54-61
  • Tidskriftsartikel (refereegranskat)abstract
    • The Rotary bell spray applicator technique is commonly used in the automotive industry for paint application because of its high transfer efficiency and high-quality result. The bell spins rapidly around its axis with a tangential velocity at the edge in the order of 100 m/s. The paint falls off the edge and enters the air with a large relative velocity, driving the atomization into small droplets where the resulting size distribution depends on the process conditions. Especially the rotation speed of the bell is an important parameter governing the size distribution. The main research question in this work is to investigate if the Taylor Analogy Breakup (TAB) model can be used to predict the resulting droplet size distributions in spray painting. As the paint is a viscous fluid a modification of the TAB model taking non-linear effects of large viscosity into account is proposed. The parameters in the breakup model are tuned by optimization to match droplet size distributions obtained in CFD simulations with measured ones. Results are presented for three cases with rotation speeds from 30 to 50 thousand RPM where the full droplet size distributions are compared with measurements. Good results are obtained for all three cases where the simulated size distributions compare well to measurements over a wide range of droplet sizes. The TAB method is able to quantitatively predict the result of the breakup process and can be used in a preprocessing stage of a full spray painting simulation, thereby reducing the need for costly and cumbersome measurements.
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8.
  • Andersson, Björn O, 1982, et al. (författare)
  • Modeling Surface Tension in SPH by Interface Reconstruction using Radial Basis Functions
  • 2010
  • Ingår i: Proceedings of the 5th International SPHERIC Workshop, 22-25 June 2010, Manchester, U.K., edited by B. D. Rogers. ; , s. 7-14
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • A novel method for reconstructing the interface between two fluids is described and evaluated. The method uses a different basis for approximating the color function than what is common practice in SPH simulations. The key feature of the new method is the ability to omit small length scale structures in order to obtain a smoother representation. A smoother interface is more suitable to derive a surface tension force from, as the magnitude of the force is proportional to the curvature which is related to the second derivative along the interface.
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9.
  • Andersson, Björn O, 1982, et al. (författare)
  • Modified TAB Model for Viscous Fluids applied to Breakup in Rotary Bell Spray Painting
  • 2012
  • Ingår i: ICLASS 2012 - 12th International Conference on Liquid Atomization and Spray Systems.
  • Konferensbidrag (refereegranskat)abstract
    • The Taylor Analogy Breakup (TAB) model is applied to droplet breakup in rotary bell spray painting commonly used in the automotive industry. The bell spins rapidly around its axis with a tangential velocity at the edge in the order of 100 m/s. The paint falls off the edge and enters the air with a large relative velocity, driving the atomization. The paint is a viscous fluid and a modification of the TAB model taking non-linear effects of large viscosity into account is described. The parameters in the breakup model are tuned to match droplet size distributions obtained in CFD simulations with measured ones. Results are presented for three cases with rotation speeds from 30 to 50 thousand RPM where the full droplet size distributions are compared with measurements. Good results are obtained for all three cases where the simulated size distributions compare well to measurements over a wide range of droplet sizes. The obtained results can be used in a preprocessing stage of a full spray painting simulation thereby reducing the need for costly and cumbersome measurements.
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11.
  • Bergh, Ingrid, 1956, et al. (författare)
  • The elderly patient’s everyday language of pain.
  • 2004
  • Ingår i: Abstract accepterad för presentation vid the 16th Annual Scientific Sessions of the Eastern Nursing Research Society (ENRS). Boston Marriott Quincy Massachusetts, USA, 2004..
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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12.
  • Bergh, Ingrid, 1956, et al. (författare)
  • Ways of talking about experiences of pain among older patients following orthopaedic surgery.
  • 2005
  • Ingår i: Journal of advanced nursing. - : Wiley. - 0309-2402 .- 1365-2648. ; 52:4, s. 351-9
  • Tidskriftsartikel (refereegranskat)abstract
    • AIM: The aim of this study was to examine how older patients who had undergone hip surgery described their experience of pain. BACKGROUND: A verbal report of pain is considered to be the single most reliable indicator of a person's pain experience. When assessing pain, healthcare professionals must be able to interpret the content of pain reports in order to understand older patient's pain experiences. METHODS: The study was carried out in two orthopaedic and two elder care wards in a large university hospital in Sweden in 2000. Altogether, 38 patients with hip replacement (mean age = 75) and 22 patients with hip fracture (mean age = 81) took part. A face-to-face interview was conducted with each patient on the second day after operation. Data were transcribed and analysed using descriptive qualitative content analysis. FINDINGS: Participants expressed their pain in a nuanced and detailed way in everyday language. Four main themes with sub-themes emerged: (a) objectification (localizing; quantifying; characterizing; temporalizing); (b) compensating (substitution; picturing); (c) explaining (functionalizing pain and its relief; externalizing pain and its relief); (d) existentializing (present pain orientation; future pain orientation). CONCLUSIONS: Exploring the ways older patients talk about pain is expected to result in a better understanding of the older patient's need of empathic individualized care and in the optimization of pain management.
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13.
  • Bergh, Ingrid, et al. (författare)
  • Worst experiences of pain and conceptions of worst pain imaginable among nursing students
  • 2008
  • Ingår i: Journal of Advanced Nursing. - : Blackwell Publishing. - 0309-2402 .- 1365-2648. ; 61:5, s. 484-491
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper is a report of a study to explore nursing students' own worst experiences of pain as well as their conceptions of the worst pain imaginable. Background.Pain is a personal experience, often assessed using a visual analogue scale. The endpoints of this scale are labelled with the extremes for pain experience (e.g. no pain to worst pain imaginable). People may understand the meaning of `no pain', but it is unclear what meaning they assign to `worst pain imaginable'. This indicates that a rating along the Visual Analogue Scale-line is dependent on the individual's previous experiences. Methods. Data were collected during the autumn of 2002. In total, 549 nursing students completed a questionnaire focusing on two main questions: `What is the worst experience of hurt, ache or pain you have had?' and `What is the worst pain imaginable for you?' Content analysis was used for data analysis. Results. The students' worst experience of pain was mostly related to acute or traumatic painful conditions, pain associated with female physiology, inflicted pain, psychological suffering and chronic painful conditions. The worst pain imaginable was described as condition-related pain, overwhelming pain, experiences of losses, deliberately inflicted pain, psychological suffering and as vicarious pain. Conclusion. The findings imply that nursing students, when they are imagining pain, include dimensions such as hope of relief, grief, control over the situation, powerlessness and empathy for and suffer with other people's pain. Further research is needed to explore why professional experience as a nurse diminishes the ability to imagine patients' pain.
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14.
  • Bergman, JP, et al. (författare)
  • Characterisation and defects in silicon carbide
  • 2002
  • Ingår i: Materials Science Forum, Vols. 389-393.
  • Konferensbidrag (refereegranskat)abstract
    • In this work we present experimental results of several defects in 4H Sic that are of interest both from a fundamental and physical point of view. And also of great importance for device applications utilizing the Sic material. These defects include the temperature stable so called D1 defect, which is created after irradiation. This optical emission has been identified as an isoelectronic defect bound at a hole attractive pseudodonor, and we have been able to correlate this to the electrically observed hole trap HS1 seen in minority carrier transient spectroscopy (MCTS). It also includes the UD1 defect observed using absorption and FTIR and which is believed to be responsible for the semi-insulating behavior of material grown by the High temperature, HTCVD technique. Finally, we have described the formation and proper-ties of critical, generated defect in high power Sic bipolar devices. This is identified as a stacking fault in the Sic basal plane, using mainly white beam synchrotron Xray topography. The stacking fault is both optically and electrically active, by forming extended local potential reduction of the conduction band.
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16.
  • Björk, Göran, 1956, et al. (författare)
  • Flow of Canadian Basin Deep Water in the Western Eurasian Basin of the Arctic Ocean
  • 2010
  • Ingår i: Deep Sea Research. - : Elsevier BV. - 0967-0637 .- 1879-0119. ; 57:4, s. 577-586
  • Tidskriftsartikel (refereegranskat)abstract
    • The LOMROG 2007 expedition targeted the previously unexplored southern part of the Lomonosov Ridge north of Greenland together with a section from the Morris Jesup Rise to Gakkel Ridge. The oceanographic data shows that Canadian Basin Deep Water (CBDW) passes the Lomonosov Ridge in the area of the Intra Basin close to the North Pole and then continues along the ridge towards Greenland and further along its northernmost continental slope. The CBDW is clearly evident as a salinity maximum and oxygen minimum at a depth of about 2000 m. The cross slope sections at the Amundsen Basin side of the Lomonosov Ridge and further south at the Morris Jesup Rise show a sharp frontal structure higher up in the water column between Makarov Basin water and Amundsen Basin water. The frontal structure continues upward into the Atlantic Water up to a depth of about 300 m. The observed water mass division at levels well above the ridge crest indicates a strong topographic steering of the flow and that different water masses tend to pass the ridge guided by ridge-crossing isobaths at local topographic heights and depressions. A rough scaling analysis shows that the extremely steep and sharply turning bathymetry of the Morris Jesup Rise may force the boundary current to separate and generate deep eddies.
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17.
  • Caesar, C., et al. (författare)
  • Beyond the neutron drip line: The unbound oxygen isotopes O-25 and O-26
  • 2013
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 88:3
  • Tidskriftsartikel (refereegranskat)abstract
    • The very neutron-rich oxygen isotopes O-25 and O-26 are investigated experimentally and theoretically. The unbound states are populated in an experiment performed at the R3B-LAND setup at GSI via proton-knockout reactions from F-26 and F-27 at relativistic energies around 442 and 414 MeV/nucleon, respectively. From the kinematically complete measurement of the decay into O-24 plus one or two neutrons, the O-25 ground-state energy and width are determined, and upper limits for the O-26 ground-state energy and lifetime are extracted. In addition, the results provide indications for an excited state in O-26 at around 4 MeV. The experimental findings are compared to theoretical shell-model calculations based on chiral two- and three-nucleon (3N) forces, including for the first time residual 3N forces, which are shown to be amplified as valence neutrons are added.
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18.
  • Chasset, Camille, et al. (författare)
  • 3-Axis magnetic control : flight results of the TANGO satellite in the PRISMA mission
  • 2013
  • Ingår i: CEAS Space Journal. - : Springer Science and Business Media LLC. - 1868-2502 .- 1868-2510. ; 5:1-2, s. 1-17
  • Tidskriftsartikel (refereegranskat)abstract
    • PRISMA implements guidance, navigation and control strategies for advanced formation flying and rendezvous experiments. The project is funded by the Swedish National Space Board and run by OHB-Sweden in close cooperation with DLR, CNES and the Danish Technical University. The PRISMA test bed consists of a fully manoeuvrable MANGO satellite as well as a 3-axis controlled TANGO satellite without any ΔV capability. PRISMA was launched on the 15th of June 2010 on board DNEPR. The TANGO spacecraft is the reference satellite for the experiments performed by MANGO, either with a "cooperative" or "non-cooperative" behaviour. Small, light and low-cost were the keywords for the TANGO design. The attitude determination is based on Sun sensors and magnetometers, and the active attitude control uses magnetic torque rods only. In order to perform the attitude manoeuvres required to fulfil the mission objectives, using any additional gravity gradient boom to passively stabilize the spacecraft was not allowed. After a two-month commissioning phase, TANGO separated from MANGO on the 11th of August 2010. All operational modes have been successfully tested, and the pointing performance in flight is in accordance with expectations. The robust Sun Acquisition mode reduced the initial tip-off rate and placed TANGO into a safe attitude in <30 min. The Manual Pointing mode was commissioned, and the spacecraft demonstrated the capability to follow or maintain different sets of attitudes. In Sun/Zenith Pointing mode, TANGO points its GPS antenna towards zenith with sufficient accuracy to track as many GPS satellites as MANGO. At the same time, it points its solar panel towards the Sun, and all payload equipments can be switched on without any restriction. This paper gives an overview of the TANGO Attitude Control System design. It then presents the flight results in the different operating modes. Finally, it highlights the key elements at the origin of the successful 3-axis magnetic control strategy on the TANGO satellite.
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20.
  • Edelvik, Fredrik, 1972, et al. (författare)
  • An improved method for dipole modeling in EEG-based source localization
  • 2009
  • Ingår i: International Federation for Medical and Biological Engineering Proceedings. - Berlin, Heidelberg : Springer Berlin Heidelberg. - 1680-0737. - 9783642038884 ; 25:9, s. 146-149
  • Konferensbidrag (refereegranskat)abstract
    • The inverse problem in EEG-based source localizationis to determine the location of the brain sources that areresponsible for the measured potentials at the scalp electrodes.The brain sources are usually modeled as current dipoles whichlead to a singularity in the right-hand side of the governing Poisson’sequation. Subtraction methods have been proposed as aremedy and in this paper an improved subtraction method formodeling the dipoles is presented. The accuracy is demonstratedfor radial and tangential sources in layered sphere models and isto the best of the authors’ knowledge superior to previous methodsfor superficial sources. An additional advantage is that itproduces a right hand side with few non-zeros which is beneficialfor efficient solution of the inverse problem.
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22.
  • Engwall, Magnus, 1965-, et al. (författare)
  • Ethoxyresorufin O-deethylase (EROD) and aryl hydrocarbon hydroxylase (AHH)-inducing potency and lethality of chlorinated naphthalenes in chicken (Gallus domesticus) and eider duck (Somateria mollissima) embryos
  • 1994
  • Ingår i: Archives of Toxicology. - : Springer Science and Business Media LLC. - 0340-5761 .- 1432-0738. ; 68:1, s. 37-42
  • Tidskriftsartikel (refereegranskat)abstract
    • The 7-ethoxyresorufin O-deethylase (EROD)- and aryl hydrocarbon hydroxylase (AHH)-inducing potencies and lethalities of a technical preparation of polychlorinated naphthalenes (PCNs) (Halowax 1014, approx imate congener ratio: 20% tetrachloronaphthalenes, 40% pentachloronaphthalenes, 40% hexachloronaphthalenes), a mixture of 50% 1,2,3,5,6,7-hexachloronaphthalene and 50% 1,2,3,4,6,7-hexachloronaphthalene (HxCN-mix), and 1,2,3,4,5,6,7-heptachloronaphthalene (HpCN) were studied in chicken (Gallus domesticus) and elder duck (Somateria mollissima) embryos. Mortality and hepatic EROD activity were determined on day 10 of incubation in chicken embryos exposed to various doses of the PCNs via the air-sacs of the eggs on day 7. The HxCN-mix and Halowax 1014 proved to have both embryolethal and EROD-inducing properties, while the HpCN had low EROD-inducing potency and embryolethality. ED(50) values for EROD induction by the HxCN-mix and Halowax 1014 were estimated to be 0.06 mg/kg egg and 0.2 mg/kg egg, respectively. Fifty percent of the chicken embryos died (6/12) when given 3.0 mg/kg of the HxCN-mix while a similar dose of Halowax 1014 caused mortality in 4 out of 12 chicken embryos. The dose-response curve for EROD induction by Halowax 1014 exhibited a decline after the maximal level was reached. When Halowax 1014 (1.0 mg/kg, egg) was coinjected with 3,3',4,4',5-pentachlorobiphenyl (PCB IUPAC #126) (0.1 mu g/kg egg) no additive effects on EROD activity were found, but when the same dose of Halowax 1014 was coinjected with a dose of PCB #126, known to cause maximal induction (1.0 mu g/kg egg), the resulting EROD activity was lower than that caused solely by 1.0 mu g PCB #126/kg egg. These findings indicate that Halowax 1014 has both EROD-inducing and EROD-inhibiting properties. Mortality and EROD and AHH activities were determined on day 18 (chicken) or day 24 (elder) of incubation in embryos exposed to 1.0 mg/kg egg via the yolk-sac on day 4 (chicken) or day 5 (elder). The HxCN-mix and Halowax 1014 induced AHH and EROD in both chicken and elder, but the induction rates were higher in the elder embryos. The HxCN-mix and Halowax 1014 caused degenerative hepatic lesions and pericardial oedema in the chicken embryos but not in the elder embryos. The most toxic PCNs tested (the HxCN-mix and Halowax 1014) were approximately of the same EROD-inducing potency as previously found for the most toxic mono-ortho-chlorinated biphenyls (Brunstrom 1990), and 1000 times less toxic and potent as EROD inducers compared with PCB #126 (Brunstrom and Andersson 1988). HpCN was considerably less toxic and exhibited a low EROD-inducing potency. The chicken embryos were more sensitive to the hepatotoxic effects produced by Halowax 1014 and the HxCN-mix than the elder duck embryos, while the elder embryos were more responsive in terms of EROD and AHH induction. The two HxCNs studied usually make up approximately 1% of the total quantity of PCNs present in Halowax 1014 [when determined with gas chromatography (flame ionization detection)]. Therefore, the relatively high toxic potency of Halowax 1014 cannot be explained by its content of the two HxCNs.
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23.
  • Fekete, Zoltán, et al. (författare)
  • [Follow-up of Cushing syndrome in western Sweden. More than one treatment method needed for cure, hormonal deficiencies common]
  • 2002
  • Ingår i: Läkartidningen. - 0023-7205. ; 99:46, s. 4635-9
  • Tidskriftsartikel (refereegranskat)abstract
    • Results from a follow-up of all patients with Cushing's syndrome who visited the Division of Endocrinology at Sahlgrenska University Hospital, Göteborg, Sweden, during 1997-1998 revealed 28 patients with ACTH-dependent disease and 3 with ACTH-independent disease. Female/male ratio was 4:1 with mean age at diagnosis 30 years. Mean time from first symptoms to diagnosis was three years (range 0-8). The most frequent signs were hypertrichosis, easy bruising, hypertension, osteoporosis and diabetes mellitus. Out of the 28 patients with ACTH-dependent disease, 16 underwent more than one treatment method (transcranial/transsphenoidal pituitary surgery, pituitary irradiation, adrenalectomy), 26 were cured and 25 developed hormonal deficiencies after treatment. Five of the 11 patients who underwent adrenalectomy developed Nelson tumors. All patients in the ACTH-independent group were cured after unilateral adrenalectomy.
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24.
  • Gamalielsson, Jonas, et al. (författare)
  • On the availability and effectiveness of open source software for digital signing of PDF documents
  • 2015
  • Ingår i: Open Source Systems: Adoption and Impact. - Cham : Springer. - 9783319178363 - 9783319178370 ; , s. 71-80
  • Konferensbidrag (refereegranskat)abstract
    • Digital signatures are important in order to ensure the integrity and authenticity of information communicated over the Internet involving different stakeholders within and beyond the borders of different nations. The topic has gained increased interest in the European context and there is legislation and project initiatives aiming to facilitate use and standardisation of digital signatures. Open standards and open source implementations of open standards are important means for the interoperability and long-term maintenance of software systems implementing digital signatures. In this paper we report from a study aiming to establish the availability and effectiveness of software provided under an open source license for digital signing and validation of PDF documents. Specifically, we characterise the use of digital signatures in Swedish Governmental agencies, report on the interoperability of open source and proprietary licensed software for digital signatures in PDF documents, and establish the effectiveness of software provided under an open source license for validation of digital signatures in PDF documents.
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25.
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26.
  • Heine, M., et al. (författare)
  • Determination of the neutron-capture rate of C-17 for r-process nucleosynthesis
  • 2017
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 95:1, s. Article no 014613 -
  • Tidskriftsartikel (refereegranskat)abstract
    • With the (RB)-B-3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C-18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C-17 into the ground state of C-18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C-18. This allowed to derive the astrophysical cross section sigma(n gamma)*. accounting for the thermal population of C-17 target states in astrophysical scenarios. The experimentally verified capture rate is significantly lower than those of previously obtained Hauser-Feshbach estimations at temperatures T-9
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27.
  • Hendo, Gina, et al. (författare)
  • Slutövning GMU: "Aldrig ge upp", Amf1, Berga örlogsbas : Muskelfysiologiska resultat
  • 2014
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Energistatus, muskelfysiologiska data och fysiskt stridsvärde studerades före och efter en 8 dygn långa grundmilitär slutövning (GMU) vid AMF-1 Berga Örlogsskolor i månadsskiftet oktober november 2013.Totalt deltog 105 soldater i övningen, fördelat på 3 plutoner om vardera 35 soldater. En subgrupp på 24 soldater (8 kvinnor) bestående av 8 soldater från vardera pluton studerades mer ingående.Medelhjärtfrekvensen för de 6 soldater (2 kvinnor) som hade i stort sett kompletta mätningar från den 187 timmar långa övningen, inklusive viloperioder, var 88 ± 7 slag/minut. Utifrån hjärtfrekvensdata beräknades den totala energiomsättningen till i genomsnitt 44 000 ± 6 600 kcal, vilket motsvarar 5 600 ± 840 kcal per dygn och 235 ± 35 kcal/tim. Total energiförbrukning var i genomsnitt 39 000 kcal för kvinnorna och 46 500 kcal för männen. I övrigt noterades inte några betydande skillnader mellan kvinnor och män. Däremot var det stora individuella variationer i energiutgift, vilka till ca hälften berodde på skillnader i kroppsvikt. Med hänsyn till kroppsvikt och buren vikt var energiförbrukningen ca 3,1 ± 0,23 kcal per timme per kg totalvikt. Den individuella variationen beror på skillnad i buren vikt, på olika uppgifter och på individuella fysiologiska skillnader.Utifrån beräknat energiintag blev det totala energiunderskottet under övningen 12 000-15 000 kcal, vilket är ca 1 500-2 000 kcal per dygn. Viktminskningen under övningen var 2,9 kg för kvinnor och 3,7 kg för män. Denna viktminskning på >4 % leder troligen till försämrad uthållighetsförmåga.Den maximala muskelstyrkan i armar och ben var i stort sett oförändrade efter övningen, liksom den beräknade maximala syreupptagningsförmågan. Däremot upplevdes ett lågintensivt cykelarbete som betydligt tyngre efter övningen. Muskeluthållighet mättes inte i denna studie.Ett skjutprov om 5 skott i liggande på 100 m mot en tredjedelsfigur visade 64 deltagande soldater på en försämrad träffprocent från 90,5% före till 79,4 % efter övningen. Alla soldater hade minst en träff före medan 6 soldater hade alla bom efter övningen.Slutsatsen från studien är att GMU-övningen resulterade i ett stort energiunderskott. Stridsvärdet, bedömt från skjutprovet var klart försämrat. Maximala fysiologiska parametrar var i stort sett oförändrade, medan skattad ansträngning och därmed uthållighetsförmåga, försämrades.
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28.
  • Henriksson, Christian, et al. (författare)
  • Reducing Bluetooth Interference with Diversity Techniques in IEEE 802.11b Networks
  • 2002
  • Ingår i: Proceedings Nordic Signal Processing Symposium.
  • Konferensbidrag (refereegranskat)abstract
    • Lately different kinds of wireless networks have become more frequently used. If they occupy the same frequency band they are likely to interfere with each other. In this paper, we examine how spatial diversity can be exploited to suppress Bluetooth interference on a IEEE 802.11b network. Two dual antenna receivers, the maximum ratio combining (MRC) and the interference rejection combining (IRC) methods, have been evaluated and compared to the ordinary single antenna receiver. Simulation results show that adding spatial diversity yields a signicant reduction in biterror rate (BER) and as a consequence the throughput is increased, especially for larger fragment sizes.
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29.
  • Jakobsson, Björn (författare)
  • Co-operation in vocational rehabilitation : methods in multiprofessional cross-sector group meetings and effects on employment
  • 2008
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The overall aim of the thesis was to acquire an increased knowledge of co-operation between different rehabilitation actors in the provision of vocational rehabilitation (VR). One aim was to investigate the differences in effects on employment between clients rehabilitated according to a systematic multi-professional cross-sector co-operation model (SMCVR) and clients subjected to conventional co-operation. A second aim was to investigate the communicative process in the rehabilitation group meetings and female clients’ experiences during the VR process.   The studies used material collected from two intervention projects, enabling natural experimental designs. Fifty-one unemployed clients with various work limitations, who underwent intervention with SMCVR I model during a period of 18 months, were individually matched into pairs using records from the Swedish Public Employment Service. Three matched comparison groups, representing the conventional way of co-operation between VR actors, were formed at local, county, and national levels. A distinctive feature of the SMCVR I model was that the client’s rehabilitation was planned by multi-professional cross-sector rehabilitation groups consisting of the client, a rehabilitation official from the social insurance office, an occupational therapist from a primary care unit, an employment counsellor from the county employment office and a social worker from the municipal social administration office. The main effect variable was the number of persons in employment. ANOVA for repeated measures for binary responses and a logistic regression model was used. The VR actors involved in the SMCVR II model were a public employer (a municipality), the social insurance office and an occupational health service. The material consisted of 22 systematic multi-professional cross-sector rehabilitation group meetings with clients who underwent intervention (20 women, 2 men). An observer attended each meeting to observe communication; each meeting was tape-recorded and subsequently transcribed. The analysis was based upon these transcriptions, using content analysis.   A larger proportion of clients subjected to this particular form of developed co-operation studied (SMCVR I) became employed during the first 2 years compared with similar clients in neighboring municipalities or among those in a national register; the higher employment rate showed a peak two years after closure of the intervention; the chance of becoming employed after rehabilitation in the 2-year follow-up was roughly twice as high as that in both comparison groups with conventional co-operation. There was a difference between the study group, the national and county comparison groups on 6 measuring occasions over the period from 1 year following closure of the intervention to the 6th year after. The logistic regression model showed that the clients with mental/social work limitations were at a greater risk of being unemployed after VR than clients with somatic work limitations. In the SMCVR II model the topics discussed primarily concerned the client’s situation regarding the field of medical and health care, previous and new work, and social insurance and none of the professionals dominated the meetings. The clients had the highest percentage of utterances. Clients were allowed ample scope to address their own requirements, thoughts and feelings. ‘Adaptation’ was a pervading theme in the discussions during the observations. The ‘importance of work’ for the clients emerged as a sub-theme; positive and neutral aspects occurred. The conflict between health and work was an ever-present theme of substantial importance for VR. Support from the employer and fellow workers during the client’s return to work was important. This support appeared as both a positive and a negative force in the VR.   In conclusion, systematic multi-professional cross-sector co-operation – which can be performed without any changes in law – leads to seeing a greater proportion of clients in employment over a long period of time compared with “co-operation as usual”. It is possible to achieve a creative communicative climate in multi-professional cross-sector rehabilitation group meetings, which can favor good results in VR.
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30.
  • Jakobsson, Björn (författare)
  • Co-operation in Vocational Rehabilitation employment : Methods in multiprofessional intersectorial group meetings and their effects on
  • 2004
  • Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • ABSTRACT Vocational rehabilitation is a complex process. As well as the client, it often involves the employer, medical professionals, national-insurance officials, employment counsellors from the employment office and social services officials. In complex cases, it is customary to arrange specific meetings between the officials from the different authorities. The overall aim of the work presented in this thesis was to increase knowledge of co-operation between different public instances in the provision of vocational rehabilitation. The main question was whether, and if so how, a group involving a client and different rehabilitation workers can improve the client�s prospects. Regarding employment outcome, a larger proportion of clients exposed to the the particular form of cooperation become employed than those in either comparison group. The higher employment rate persisted two years after the end of rehabilitation and the chance of becoming employed after rehabilitation was about twice that of people in either group of conventional rehabilitation.
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31.
  • Jakobsson, Björn, et al. (författare)
  • Do systematic multiprofessional rehabilitation group meetings improve efficiency in vocational rehabilitation?
  • 2005
  • Ingår i: Work. - 1051-9815 .- 1875-9270. ; 24:3, s. 279-290
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: The aim of the present study was to investigate differences in the effects on employment between clients whose rehabilitation was coordinated in systematic multiprofessional rehabilitation group meetings and clients whose rehabilitation was coordinated in the "conventional" way. METHOD: The study was based on a sample of 51 individuals who received systematic group meeting coordination. All individuals in the study group were unemployed before the rehabilitation intervention. Two different comparison groups were chosen: one at a local level and another at a national level. The groups were matched on an individual level based on records obtained from The National Labour Market Board (AMS) and The National Social Insurance Board (RFV). The data were analysed by an analysis of variance (ANOVA) for repeated measures for binary responses. RESULTS: 68.6% in the study group and 49% in both the local comparison group and national group had some form of employment 24 months after rehabilitation. The ANOVA analyses (in terms of odds ratio) found that when all measurement points (6, 12 and 24 months after the rehabilitation) were included in the calculations that there was twice as high a chance of becoming employed after having received rehabilitation services through the multiprofessional group than for both comparison groups. The majority of employment in all the groups was associated with some form of subsidy or sheltered employment.
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32.
  • Jakobsson, Björn, et al. (författare)
  • Improved co-operation in vocational rehabilitation with systematic rehabilitation group meetings.
  • 2002
  • Ingår i: Disability and Rehabilitation. - : Informa UK Limited. - 0963-8288 .- 1464-5165. ; 24:14, s. 734-740
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: The present aim was to investigate the communicative pattern in two rehabilitation groups. The rehabilitation group consisted of the client, a supervisor, an employer representative, an occupational health physician, a rehabilitation counsellor from the national social insurance office and a support person. METHOD: Participatory observation of 22 rehabilitation meetings. The communication was tape-recorded and transcribed word for word. The transcripts were coded and analysed both qualitatively and quantitatively. RESULTS AND CONCLUSION: The client made the most utterances in the groups, but most often in the form of answers to questions from the other actors. Following the client, the physician made the next most frequent utterances, most often as questions. The subjects most discussed concerned the client's situation regarding work, health and material support. None of the "professionals" dominated the meetings, although one picture that emerged was that the physician and employer representative played more prominent roles as takers of initiative and as coordinators while the client was more passive than the other actors. The discussions were calm and much latitude was allowed for the participants to put forward their own requirements, thoughts and feelings. The rehabilitation group may be viewed as a meeting place for "experts" and clients. The further management of the rehabilitation was by the actor the client most immediately needed. In this, rehabilitation in the rehabilitation group differs from the "case management" common in the rehabilitation field.
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33.
  • Jakobsson, Björn, et al. (författare)
  • Improved employment rates after multiprofessional cross-sector cooperation in vocational rehabilitation: A 6-year follow-up with comparison groups
  • 2010
  • Ingår i: International Journal of Rehabilitation Research. - 0342-5282 .- 1473-5660. ; 33:1, s. 72-80
  • Tidskriftsartikel (refereegranskat)abstract
    • The objective of this study was to better understand the long-term effects of an improved model for cooperation on employment between rehabilitation professionals in vocational rehabilitation (VR). To compare these effects with those associated with the traditional model of cooperation. The study featured a group of patients who participated in a developmental project. All of the patients had some degree of restricted work capacity, which was evidenced somatically as well as mentally/socially. They had all experienced long periods of unemployment during the 2-year period before the intervention. A 'natural experiment study design' that relied on database records was used. Using matching criteria, we identified 'social twins' from a government register to create comparison groups at the local, county and national levels (n=4×51 patients). Repeated-measures analysis of variance and logistic regression were used to analyse the data. The majority (59%) of the study group was employed 3 years after the intervention compared with 39 and 41% in the two matched control groups, respectively. The corresponding figures after 6 years were 51 versus 39 and 37%. An individual with a somatically restricted work capacity was about twice as likely to secure gainful employment following VR as compared with an individual with a mentally/socially restricted work capacity. In conclusion, the study focused on an improved method of cooperation between rehabilitation actors in the context of VR programmes. A model that included systematic multiprofessional cross-sector group meetings was explored, and we concluded that a substantial percentage of the enrolled patients successfully secured employment over a 6-year period. This percentage exceeded that of matched pairs in a county and national group; we presume that these groups represented 'the usual form of cooperation'.
  •  
34.
  • Jakobsson, Björn, et al. (författare)
  • Multi-professional vocational rehabilitation group meetings with female clients - a qualitative study.
  • 2008
  • Ingår i: Work. - 1051-9815 .- 1875-9270. ; 30:4, s. 413-421
  • Tidskriftsartikel (refereegranskat)abstract
    • Many women require vocational rehabilitation before they can return to work. The objective with the present study was to describe female clients' situation during the rehabilitation process, as it became apparent during the rehabilitation meetings with the various actors involved. The clients' diagnoses varied, but the majority was affected with musculoskeletal disorders. The meetings were audio-taped and transcribed verbatim, after which they were analysed by qualitative content analysis. The following themes emerged: Adaptation to the rehabilitation group; client's health status; the workplace's significance for rehabilitation; and the client's decision-point. Conflict between health and work was immensely important for rehabilitation. Differences in attitude were apparent during the rehabilitation meetings, as some clients were passive and exercised less influence on the planning, than the other more active clients did.
  •  
35.
  • Jakobsson, Björn, et al. (författare)
  • Rehabilitering i Samverkan En process- och registerstudie av Betagruppens arbete i Kungsbacka kommun
  • 2004
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • Syftet med föreliggande rapport är att undersöka den fortsatta utvecklingen av arbetsmetoden; systematiserade flerpartssamtal och att studera effekterna av rehabiliteringsarbetet i Betagruppen. Den föregående utvärderingen av Betaprojektet hade en före- och efterdesign och det var inte så lätt att ställa resultaten av utvärderingen i relation till mera �konventionell� handläggning av rehabiliteringsärenden. För att få en uppfattning om effekterna av Betas arbetssätt jämförs i denna studie Betas arbetssätt med effekter av att arbeta mera �konventionellt�. I studien matchas Betagruppen med individer från andra kommuner i närområdet som har en liknande struktur som Kungsbacka kommun. Dessutom görs också en jämförelse med en riksgrupp. För att få fram effekter av de båda arbetssätten används registerstudier och för att få fram kunskaper om Betagruppens utveckling av samverkan mellan rehabiliteringsaktörerna och eventuella förändringar används gruppintervjuer och enkät.
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36.
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37.
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38.
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39.
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40.
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41.
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42.
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43.
  • Jakobsson, Hedvig, et al. (författare)
  • Macrolide resistance in the normal microbiota after Helicobacter pylori treatment
  • 2007
  • Ingår i: Scandinavian Journal of Infectious Diseases. - Oslo, Norway : Taylor & Francis. - 0036-5548 .- 1651-1980. ; 39:9, s. 757-63
  • Tidskriftsartikel (refereegranskat)abstract
    • Large-scale chemoprevention of peptic ulcer disease and gastric cancer through eradication of Helicobacter pylori would expose large population groups to antibiotics, which raises concerns about possible dissemination of antibiotic resistance. The objective of this cohort study was to determine whether a triple therapy, containing omeprazole, clarithromycin, and metronidazole, of H. pylori infection increases the prevalence of macrolide resistance in the normal microbiota. 85 patients with a peptic ulcer disease with verified H. pylori infection and 12 dyspeptic patients without positive findings upon endoscopy were included. Minimal inhibitory concentrations of clarithromycin for Staphylococcus, Streptococcus, Enterococcus and Bacteroides spp. were determined from samples taken before and after treatment, and 1 y later. Before treatment, macrolide resistance was observed in 11%, 31%, 9% and 11% of the staphylococci, streptococci, enterococci and Bacteroides, respectively. The number of resistant isolates remained elevated after 1 y, most notably for staphylococci and streptococci. No development of persistent resistance was detected in the untreated control group. Triple therapy including clarithromycin leads to persistent macrolide resistance in the normal microbiota. A prevalent pool of resistance genes in the normal microbiota constitutes an ecological hazard that needs to be considered before global treatment programmes for eradication of H. pylori are implemented.
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44.
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45.
  • Jakobsson, Martin, 1966-, et al. (författare)
  • An Arctic Ocean ice shelf during MIS 6 constrained by new geophysical and geological data
  • 2010
  • Ingår i: Quaternary Science Reviews. - : Elsevier BV. - 0277-3791 .- 1873-457X. ; 29:25-26, s. 3505-3517
  • Tidskriftsartikel (refereegranskat)abstract
    • The hypothesis of floating ice shelves covering the Arctic Ocean during glacial periods was developed in the 1970s. In its most extreme form, this theory involved a 1000 m thick continuous ice shelf covering the Arctic Ocean during Quaternary glacial maxima including the Last Glacial Maximum (LGM). While recent observations clearly demonstrate deep ice grounding events in the central Arctic Ocean, the ice shelf hypothesis has been difficult to evaluate due to a lack of information from key areas with severe sea ice conditions. Here we present new data from previously inaccessible, unmapped areas that constrain the spatial extent and timing of marine ice sheets during past glacials. These data include multibeam swath bathymetry and subbottom profiles portraying glaciogenic features on the Chukchi Borderland, southern Lomonosov Ridge north of Greenland, Morris Jesup Rise, and Yermak Plateau. Sediment cores from the mapped areas provide age constraints on the glaciogenic features. Combining these new geophysical and geological data with earlier results suggests that an especially extensive marine ice sheet complex, including an ice shelf, existed in the Amerasian Arctic Ocean during Marine Isotope Stage (MIS) 6. From a conceptual oceanographic model we speculate that the cold halocline of the Polar Surface Water may have extended to deeper water depths during MIS 6 inhibiting the warm Atlantic water from reaching the Amerasian Arctic Ocean and, thus, creating favorable conditions for ice shelf development. The hypothesis of a continuous 1000 m thick ice shelf is rejected because our mapping results show that several areas in the central Arctic Ocean substantially shallower than 1000 m water depth are free from glacial influence on the seafloor.
  •  
46.
  • Jakobsson, Martin, et al. (författare)
  • Evidence for an ice shelf covering the central Arctic Ocean during the penultimate glaciation
  • 2016
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
  • Tidskriftsartikel (refereegranskat)abstract
    • The hypothesis of a km-thick ice shelf covering the entire Arctic Ocean during peak glacial conditions was proposed nearly half a century ago. Floating ice shelves preserve few direct traces after their disappearance, making reconstructions difficult. Seafloor imprints of ice shelves should, however, exist where ice grounded along their flow paths. Here we present new evidence of ice-shelf groundings on bathymetric highs in the central Arctic Ocean, resurrecting the concept of an ice shelf extending over the entire central Arctic Ocean during at least one previous ice age. New and previously mapped glacial landforms together reveal flow of a spatially coherent, in some regions41-km thick, central Arctic Ocean ice shelf dated to marine isotope stage 6 (similar to 140 ka). Bathymetric highs were likely critical in the ice-shelf development by acting as pinning points where stabilizing ice rises formed, thereby providing sufficient back stress to allow ice shelf thickening.
  •  
47.
  • Jakobsson, Martin, et al. (författare)
  • Geological record of ice shelf break-up and grounding line retreat, Pine Island Bay, West Antarctica
  • 2011
  • Ingår i: Geology. - 0091-7613 .- 1943-2682. ; 39:7, s. 691-694
  • Tidskriftsartikel (refereegranskat)abstract
    • The catastrophic break-ups of the floating Larsen A and B ice shelves (Antarctica) in 1995 and 2002 and associated acceleration of glaciers that flowed into these ice shelves were among the most dramatic glaciological events observed in historical time. This raises a question about the larger West Antarctic ice shelves. Do these shelves, with their much greater glacial discharge, have a history of collapse? Here we describe features from the seafloor in Pine Island Bay, West Antarctica, which we interpret as having been formed during a massive ice shelf break-up and associated grounding line retreat. This evidence exists in the form of seafloor landforms that we argue were produced daily as a consequence of tidally influenced motion of mega-icebergs maintained upright in an iceberg armada produced from the disintegrating ice shelf and retreating grounding line. The break-up occurred prior to ca. 12 ka and was likely a response to rapid sea-level rise or ocean warming at that time.
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