| 1. |
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| 2. |
- Reifarth, R., et al.
(författare)
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Nuclear astrophysics with radioactive ions at FAIR
- 2016
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Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
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Konferensbidrag (refereegranskat)abstract
- The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
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| 3. |
- Veres, P., et al.
(författare)
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Observation of inverse Compton emission from a long gamma-ray burst
- 2019
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Ingår i: Nature. - : NATURE PUBLISHING GROUP. - 0028-0836 .- 1476-4687. ; 575:7783, s. 459-
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Tidskriftsartikel (refereegranskat)abstract
- Long-duration gamma-ray bursts (GRBs) originate from ultra-relativistic jets launched from the collapsing cores of dying massive stars. They are characterized by an initial phase of bright and highly variable radiation in the kiloelectron volt-to-mega electronvoltband, which is probably produced within the jet and lasts from milliseconds to minutes, known as the prompt emission(1,2). Subsequently, the interaction of the jet with the surrounding medium generates shock waves that are responsible for the afterglow emission, which lasts from days to months and occurs over a broad energy range from the radio to the gigaelectronvolt bands(1-6). The afterglow emission is generally well explained as synchrotron radiation emitted by electrons accelerated by the external shock(7-9). Recently, intense long-lasting emission between 0.2 and 1 teraelectronvolts was observed from GRB 190114C(10,11). Here we report multifrequency observations of GRB 190114C, and study the evolution in time of the GRB emission across 17 orders of magnitude in energy, from 5 x 10(-6) to 10(12) electronvolts. We find that the broadband spectral energy distribution is double-peaked, with the teraelectronvolt emission constituting a distinct spectral component with power comparable to the synchrotron component. This component is associated with the afterglow and is satisfactorily explained by inverse Compton up-scattering of synchrotron photons by high-energy electrons. We find that the conditions required to account for the observed teraelectronvolt component are typical for GRBs, supporting the possibility that inverse Compton emission is commonly produced in GRBs.
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| 4. |
- Altstadt, S.G., et al.
(författare)
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B-13,B-14(n,gamma) via Coulomb Dissociation for Nucleosynthesis towards the r-Process
- 2014
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Ingår i: Nuclear Data Sheets. - : Elsevier BV. - 1095-9904 .- 0090-3752. ; 120, s. 197-200
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Konferensbidrag (refereegranskat)abstract
- Radioactive beams of 14,15B produced by fragmentation of a primary 40Ar beam were directed onto a Pb target to investigate the neutron breakup within the Coulomb field. The experiment was performed at the LAND/R3B setup. Preliminary results for the Coulomb dissociation cross sections as well as for the astrophysically interesting inverse reactions, 13,14B(n,γ), are presented.
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| 5. |
- Blunden, Jessica, et al.
(författare)
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State of the Climate in 2012
- 2013
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Ingår i: Bulletin of The American Meteorological Society - (BAMS). - 0003-0007 .- 1520-0477. ; 94:8, s. S1-S258
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Tidskriftsartikel (refereegranskat)abstract
- For the first time in serveral years, the El Nino-Southern Oscillation did not dominate regional climate conditions around the globe. A weak La Ni a dissipated to ENSOneutral conditions by spring, and while El Nino appeared to be emerging during summer, this phase never fully developed as sea surface temperatures in the eastern conditions. Nevertheless, other large-scale climate patterns and extreme weather events impacted various regions during the year. A negative phase of the Arctic Oscillation from mid-January to early February contributed to frigid conditions in parts of northern Africa, eastern Europe, and western Asia. A lack of rain during the 2012 wet season led to the worst drought in at least the past three decades for northeastern Brazil. Central North America also experienced one of its most severe droughts on record. The Caribbean observed a very wet dry season and it was the Sahel's wettest rainy season in 50 years. Overall, the 2012 average temperature across global land and ocean surfaces ranked among the 10 warmest years on record. The global land surface temperature alone was also among the 10 warmest on record. In the upper atmosphere, the average stratospheric temperature was record or near-record cold, depending on the dataset. After a 30-year warming trend from 1970 to 1999 for global sea surface temperatures, the period 2000-12 had little further trend. This may be linked to the prevalence of La Ni a-like conditions during the 21st century. Heat content in the upper 700 m of the ocean remained near record high levels in 2012. Net increases from 2011 to 2012 were observed at 700-m to 2000-m depth and even in the abyssal ocean below. Following sharp decreases in to the effects of La Ni a, sea levels rebounded to reach records highs in 2012. The increased hydrological cycle seen in recent years continued, with more evaporation in drier locations and more precipitation in rainy areas. In a pattern that has held since 2004, salty areas of the ocean surfaces and subsurfaces were anomalously salty on average, while fresher areas were anomalously fresh. Global tropical cyclone activity during 2012 was near average, with a total of 84 storms compared with the 1981-2010 average of 89. Similar to 2010 and 2011, the North Atlantic was the only hurricane basin that experienced above-normal activity. In this basin, Sandy brought devastation to Cuba and parts of the eastern North American seaboard. All other basins experienced either near-or below-normal tropical cyclone activity. Only three tropical cyclones reached Category 5 intensity-all in Bopha became the only storm in the historical record to produce winds greater than 130 kt south of 7 N. It was also the costliest storm to affect the Philippines and killed more than 1000 residents. Minimum Arctic sea ice extent in September and Northern Hemisphere snow cover extent in June both reached new record lows. June snow cover extent is now declining at a faster rate (-17.6% per decade) than September sea ice extent (-13.0% per decade). Permafrost temperatures reached record high values in northernmost Alaska. A new melt extent record occurred on 11-12 July on the Greenland ice sheet; 97% of the ice sheet showed some form of melt, four times greater than the average melt for this time of year. The climate in Antarctica was relatively stable overall. The largest maximum sea ice extent since records begain in 1978 was observed in September 2012. In the stratosphere, warm air led to the second smallest ozone hole in the past two decades. Even so, the springtime ozone layer above Antarctica likely will not return to its early 1980s state until about 2060. Following a slight decline associated with the global 2 emissions from fossil fuel combustion and cement production reached a record 9.5 +/- 0.5 Pg C in 2011 and a new record of 9.7 +/- 0.5 Pg C is estimated for 2012. Atmospheric CO2 concentrations increased by 2.1 ppm in 2012, to 392.6 ppm. In spring 2012, 2 concentration exceeded 400 ppm at 7 of the 13 Arctic observation sites. Globally, other greenhouse gases including methane and nitrous oxide also continued to rise in concentration and the combined effect now represents a 32% increase in radiative forcing over a 1990 baseline. Concentrations of most ozone depleting substances continued to fall.
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| 6. |
- Borglin, Gunilla, et al.
(författare)
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Older people in Sweden with various degrees of present quality of life : their health, social support, everyday activities and sense of coherence.
- 2006
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Ingår i: Health & Social Care in the Community. - : Blackwell Publishing. - 0966-0410 .- 1365-2524. ; 14:2, s. 136-146
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Tidskriftsartikel (refereegranskat)abstract
- Public health policies in most European countries are concerned with how to keep older people living independently with a qualitatively good life in the community as long as possible. However, knowledge about what may characterise those seemingly 'healthy' older people is sparse. The aim of the study was to investigate the characteristics of a sample of people (75+) reporting various degrees of Quality of Life (QoL) with respect to QoL in different areas, as well as self-rated health, health problems, social support, everyday activities and sense of coherence. A postal questionnaire was sent out in spring 2001 to a randomly selected population-based sample (n= 600) in the southern parts of Sweden. A two-step cluster analysis was performed (n= 385, mean age 84.6, SD = 5.7) with 'present QoL' as clustering attribute. Three groups were disclosed, classified as high, intermediate and low present QoL, of which 33.8% could be regarded being at risk of low QoL. Those with low present QoL (18.4%) were the oldest and most vulnerable, a majority were women with 'poor or bad' self-rated health, high frequencies of health problems, low total QoL, low social support and sense of coherence and less physically active. Those with high present QoL (47.8%) reported more 'excellent or good' self-rated health, physical activity, satisfactory social support and higher sense of coherence and total QoL than the other two groups. Those with intermediate present QoL (33.8%) had more of 'poor or bad' self-rated health, more health problems were less physically active, had lower total QoL and sense of coherence, and less social support than those with high present QoL. The sample seemed to reflect the ageing process in that the respondents were at different stages of ageing. However, the fact that the level of social support, sense of coherence and self-rated health followed the same curve as QoL may indicate that some are more vulnerable to low present QoL given the same health and these should be targeted in preventive programmes since they report low QoL.
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| 7. |
- Caesar, C., et al.
(författare)
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Beyond the neutron drip line: The unbound oxygen isotopes O-25 and O-26
- 2013
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Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 88:3
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Tidskriftsartikel (refereegranskat)abstract
- The very neutron-rich oxygen isotopes O-25 and O-26 are investigated experimentally and theoretically. The unbound states are populated in an experiment performed at the R3B-LAND setup at GSI via proton-knockout reactions from F-26 and F-27 at relativistic energies around 442 and 414 MeV/nucleon, respectively. From the kinematically complete measurement of the decay into O-24 plus one or two neutrons, the O-25 ground-state energy and width are determined, and upper limits for the O-26 ground-state energy and lifetime are extracted. In addition, the results provide indications for an excited state in O-26 at around 4 MeV. The experimental findings are compared to theoretical shell-model calculations based on chiral two- and three-nucleon (3N) forces, including for the first time residual 3N forces, which are shown to be amplified as valence neutrons are added.
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| 8. |
- Heine, M., et al.
(författare)
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Determination of the neutron-capture rate of C-17 for r-process nucleosynthesis
- 2017
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Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 95:1, s. Article no 014613 -
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Tidskriftsartikel (refereegranskat)abstract
- With the (RB)-B-3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C-18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C-17 into the ground state of C-18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C-18. This allowed to derive the astrophysical cross section sigma(n gamma)*. accounting for the thermal population of C-17 target states in astrophysical scenarios. The experimentally verified capture rate is significantly lower than those of previously obtained Hauser-Feshbach estimations at temperatures T-9
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| 9. |
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| 10. |
- Magnusson, Gunilla, 1968, et al.
(författare)
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Evaluation of screening procedures for congenital cataracts.
- 2003
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Ingår i: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 0803-5253 .- 1651-2227. ; 92:12, s. 1468-73
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. METHODS: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3). RESULTS: Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region 1 differed significantly from Regions 2 and 3, which were more similar and were combined for further analysis. The difference in detected cases was greatest at 21 d of age (55% vs 18%; p < 0.001), but persisted even at 100 d of age (78% vs 64%; p < 0.02). Region 1 screening resulted in more and earlier cases detected than the other two regions (22 vs 15 per 100,000 births). In 72% of all cases, surgery was performed in response to referrals from either the maternity wards (36%), or the well-baby clinics (36%). However, half of the cases from the well-baby clinics were detected too late, i.e. at > 100 d. CONCLUSION: Eye screening in the maternity ward is preferable to well-baby clinic screening and to no screening at all, since it leads to early detection. Screening should also be performed routinely at well-baby clinics within the period when successful treatment is possible.
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| 11. |
- Tanvir, N. R., et al.
(författare)
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The Emergence of a Lanthanide-rich Kilonova Following the Merger of Two Neutron Stars
- 2017
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Ingår i: Astrophysical Journal Letters. - : American Astronomical Society. - 2041-8205 .- 2041-8213. ; 848:2
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Tidskriftsartikel (refereegranskat)abstract
- We report the discovery and monitoring of the near-infrared counterpart (AT2017gfo) of a binary neutron-star merger event detected as a gravitational wave source by Advanced Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo (GW170817) and as a short gamma-ray burst by Fermi Gamma-ray Burst Monitor (GBM) and Integral SPI-ACS (GRB 170817A). The evolution of the transient light is consistent with predictions for the behavior of a kilonova/ macronova powered by the radioactive decay of massive neutron-rich nuclides created via r-process nucleosynthesis in the neutron-star ejecta. In particular, evidence for this scenario is found from broad features seen in Hubble Space Telescope infrared spectroscopy, similar to those predicted for lanthanide-dominated ejecta, and the much slower evolution in the near-infrared K-s-band compared to the optical. This indicates that the late-time light is dominated by high-opacity lanthanide-rich ejecta, suggesting nucleosynthesis to the third r-process peak (atomic masses A approximate to 195). This discovery confirms that neutron-star mergers produce kilo-/macronovae and that they are at least a major-if not the dominant-site of rapid neutron capture nucleosynthesis in the universe.
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| 12. |
- Thies, Ronja, 1987, et al.
(författare)
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Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes
- 2016
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Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 93:5
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Tidskriftsartikel (refereegranskat)abstract
- Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neutron-rich nuclei, creating a need for models to describe also these reactions. Purpose: We want to extend the presently available data on fragmentation reactions towards the light exotic region on the nuclear chart. Furthermore, we want to improve the understanding of projectile fragmentation especially for unstable isotopes. Method: We have measured projectile fragments from C10,12-18 and B10-15 isotopes colliding with a carbon target. These measurements were all performed within one experiment, which gives rise to a very consistent data set. We compare our data to model calculations. Results: One-proton removal cross sections with different final neutron numbers (1pxn) for relativistic C10,12-18 and B10-15 isotopes impinging on a carbon target. Comparing model calculations to the data, we find that the epax code is not able to describe the data satisfactorily. Using abrabla07 on the other hand, we find that the average excitation energy per abraded nucleon needs to be decreased from 27 MeV to 8.1 MeV. With that decrease abrabla07 describes the data surprisingly well. Conclusions: Extending the available data towards light unstable nuclei with a consistent set of new data has allowed a systematic investigation of the role of the excitation energy induced in projectile fragmentation. Most striking is the apparent mass dependence of the average excitation energy per abraded nucleon. Nevertheless, this parameter, which has been related to final-state interactions, requires further study.
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| 13. |
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| 14. |
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| 15. |
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| 16. |
- Bianco, L., et al.
(författare)
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alpha-Decay branching ratios measured by gamma-ray tagging
- 2008
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 597:2-3, s. 189-191
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Forskningsöversikt (refereegranskat)abstract
- The nuclides Pt168-170 were produced by bombarding isotopically enriched Mo-92,Mo-94 targets with 336, 348 MeV Kr-78 ions. Prompt gamma rays were detected at the target position and provided a selection criterion for the Pt168-170 nuclei. This technique enables the problem of the background from higher-energy alpha decays in the spectrum to be circumvented. The Pt nuclei were separated in flight using the gas-filled separator RITU and implanted into the GREAT spectrometer, which was used to study subsequent alpha decays. The alpha-decay branching ratios of Os164-166 were deduced from the fraction of selected Pt168-170 nuclei correlated with a decays Of Os164-166. The resulting branching ratios agree with the literature values but can have improved precision.
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| 17. |
- Bianco, L., et al.
(författare)
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Discovery of W-157 and Os-161
- 2010
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 690:1, s. 15-18
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Tidskriftsartikel (refereegranskat)abstract
- The nuclides W-157 and Os-161 have been discovered ill reactions of Ni-58 ion beams with a Cd-106 target. The Os-161 alpha-decay energy and half-life were 6890 +/- 12 keV and 640 +/- 60 mu s. The daughter W-157 nuclei beta-decayed with a half-life of 275 +/- 40 ms, populating both low-lying alpha-decaying states in Ta-157, which is consistent with a 7/2(-) ground state in W-157. Fine structure observed in the alpha decay of Os-161 places the lowest excited state in W-157 with 1(pi) = 9/2(-) at 318 +/- 30 key. The branching ratio of 5.5(-2.2)(+3.1)% indicates that Os-161 also has a 7/2(-) ground state. Shell-model calculations analysing the effects of monopole shifts and a tensor force on the relative energies of 2f(7/2) and 1h(9/2) neutron states in N = 83 isotones are presented. (C) 2010 Elsevier B.V. All rights reserved.
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| 18. |
- Bonde, J. P. E., et al.
(författare)
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COVID-19-related hospital admission in spouses of partners in at-risk occupations
- 2023
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Ingår i: Scandinavian Journal of Work Environment & Health. - : Scandinavian Journal of Work, Environment and Health. - 0355-3140 .- 1795-990X. ; 49:3, s. 193-200
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Tidskriftsartikel (refereegranskat)abstract
- Objective This study aimed to quantify the risk of COVID-19-related hospital admission in spouses living with partners in at-risk occupations in Denmark during 2020-21.Methods Within a registry-based cohort of all Danish employees (N=2 451 542), we identified cohabiting couples, in which at least one member (spouse) held a job that according to a job exposure matrix entailed low risk of occupational exposure to SARS-CoV-2 (N=192 807 employees, 316 COVID-19 hospital admissions). Risk of COVID-19-related hospital admission in such spouses was assessed according to whether their partners were in jobs with low, intermediate or high risk for infection. Overall and sex-specific incidence rate ratios (IRR) of COVID-19-related hospital admission were computed by Poisson regression with adjustment for relevant covariates.Results The risk of COVID-19-related hospital admission was increased among spouses with partners in highrisk occupations [adjusted IRR (IRRadj)1.59, 95% confidence interval (CI) 1.1-2.2], but not intermediate-risk occupations (IRRadj 0.97 95% 0.8-1.3). IRR for having a partner in a high-risk job was elevated during the first three pandemic waves but not in the fourth (IRRadj 0.48 95% CI 0.2-1.5). Sex did not modify the risk of hospital admission.Conclusions SARS-CoV-2 transmission at the workplace may pose an increased risk of severe COVID-19 among spouses in low-risk jobs living with partners in high-risk jobs, which emphasizes the need for preventive measures at the workplace in future outbreaks of epidemic contagious disease. When available, effective vaccines seem essential.
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| 19. |
- Bonde, J. P. E., et al.
(författare)
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Occupational risk of COVID-19 across pandemic waves: a two-year national follow-up study of hospital admissions
- 2022
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Ingår i: Scandinavian Journal of Work Environment & Health. - : Scandinavian Journal of Work, Environment and Health. - 0355-3140 .- 1795-990X. ; 48:8, s. 672-677
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Tidskriftsartikel (refereegranskat)abstract
- Objective Assuming that preventive measures to mitigate viral transmission of SARS-CoV-2 at the workplace may have been improved in the course of the COVID-19 pandemic, we examined the occupational risk of COVID-19 related hospital admission across the four pandemic waves in Denmark between week 8, 2020, and week 50, 2021. Methods The study included 4416 cases of COVID-19 related hospital admissions among 2.4 million Danish employees aged 20-69 with follow-up in 2020 through 2021. At-risk industrial sectors and a reference population were defined a priory by a job-exposure matrix on occupational risk for COVID-19. Incidence rate ratios (IRR) and potential effect modification by pandemic wave were computed with Poisson regression adjusted for demographic, social and health factors including completed COVID-19 vaccination. Results We observed an overall elevated relative risk in four of six at-risk industrial sectors, but the pandemic wave only modified the risk among healthcare employees, where the excess risk from a high initial level declined to background levels during the latest waves in models not adjusting for COVID-19 vaccination. In social care, education and transport, the elevated risk was not modified by pandemic wave. Conclusion Danish healthcare employees were to some extent protected against occupational transmission of SARS-CoV-2 during the two last pandemic waves even though the absolute risk conferred by occupation may not have been eliminated. Early vaccination of this group seems not to be the only explanation. The risk in other sectors remained elevated indicating a need to revisit preventive measures.
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| 20. |
- Bonde, J P E, et al.
(författare)
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Occupational risk of COVID-19 in foreign-born employees in Denmark
- 2023
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Ingår i: Occupational Medicine. - : Oxford University Press. - 0962-7480 .- 1471-8405.
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Foreign-born workers in high-income countries experience higher rates of COVID-19 but the causes are only partially known. AIMS: To examine if the occupational risk of COVID-19 in foreign-born workers deviates from the risk in native-born employees in Denmark. METHODS: Within a registry-based cohort of all residents employed in Denmark (n = 2 451 542), we identified four-digit DISCO-08 occupations associated with an increased incidence of COVID-19-related hospital admission during 2020-21 (at-risk occupations). The sex-specific prevalence of at-risk employment in foreign born was compared with the prevalence in native born. Moreover, we examined if the country of birth modified the risk of a positive SARS-CoV-2 polymerase chain reaction (PCR) test and COVID-19-related hospital admission in at-risk occupations. RESULTS: Workers born in low-income countries and male workers from Eastern Europe more often worked in at-risk occupations (relative risks between 1.16 [95% confidence interval {CI} 1.14-1.17] and 1.87 [95% CI 1.82-1.90]). Being foreign-born modified the adjusted risk of PCR test positivity (test for interaction P < 0.0001), primarily because of higher risk in at-risk occupations among men born in Eastern European countries (incidence rate ratio [IRR] 2.39 [95% CI 2.09-2.72] versus IRR 1.19 [95% CI 1.14-1.23] in native-born men). For COVID-19-related hospital admission, no overall interaction was seen, and in women, country of birth did not consistently modify the occupational risk. CONCLUSIONS: Workplace viral transmission may contribute to an excess risk of COVID-19 in male workers born in Eastern Europe, but most foreign-born employees in at-risk occupations seem not to be at higher occupational risk than native born.
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| 21. |
- Bonde, J. P. E., et al.
(författare)
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Occupational risk of SARS-CoV-2 infection: a nationwide register-based study of the Danish workforce during the COVID-19 pandemic, 2020-2021
- 2023
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Ingår i: Occupational and Environmental Medicine. - : BMJ. - 1351-0711 .- 1470-7926. ; 80:4, s. 202-208
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveMost earlier studies on occupational risk of COVID-19 covering the entire workforce are based on relatively rare outcomes such as hospital admission and mortality. This study examines the incidence of SARS-CoV-2 infection by occupational group based on real-time PCR (RT-PCR) tests. MethodsThe cohort includes 2.4 million Danish employees, 20-69 years of age. All data were retrieved from public registries. The incidence rate ratios (IRRs) of first-occurring positive RT-PCR test from week 8 of 2020 to week 50 of 2021 were computed by Poisson regression for each four-digit Danish Version of the International Standard Classification of Occupations job code with more than 100 male and 100 female employees (n=205). Occupational groups with low risk of workplace infection according to a job exposure matrix constituted the reference group. Risk estimates were adjusted by demographic, social and health characteristics including household size, completed COVID-19 vaccination, pandemic wave and occupation-specific frequency of testing. ResultsIRRs of SARS-CoV-2 infection were elevated in seven healthcare occupations and 42 occupations in other sectors, mainly social work activities, residential care, education, defence and security, accommodation and transportation. No IRRs exceeded 2.0. The relative risk in healthcare, residential care and defence/security declined across pandemic waves. Decreased IRRs were observed in 12 occupations. DiscussionWe observed a modestly increased risk of SARS-CoV-2 infection among employees in numerous occupations, indicating a large potential for preventive actions. Cautious interpretation of observed risk in specific occupations is needed because of methodological issues inherent in analyses of RT-PCR test results and because of multiple statistical tests.
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| 22. |
- Briselet, R., et al.
(författare)
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Production cross section and decay study of Es 243 and Md 249
- 2019
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Ingår i: Physical Review C. - 2469-9985. ; 99:2
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Tidskriftsartikel (refereegranskat)abstract
- In the study of the odd-Z, even-N nuclei Es243 and Md249, performed at the University of Jyväskylä, the fusion-evaporation reactions Au197(Ca48,2n)Es243 and Tl203(Ca48,2n)Md249 have been used for the first time. Fusion-evaporation residues were selected and detected using a gas-filled separator coupled with its focal-plane spectrometer. For Es243, the recoil decay correlation analysis yielded a half-life of 24±3s and a maximum production cross section of 37±10nb. In the same way, a half-life of 26±1s, an α-branching ratio of 75±5%, and a maximum production cross section of 300±80nb were determined for Md249. The decay properties of Es245, the daughter of Md249, were also measured: an α-branching ratio of 54±7% and a half-life of 65±6s. Experimental cross sections were compared to the results of calculations performed using the kewpie2 statistical fusion-evaporation code.
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| 23. |
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| 24. |
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| 25. |
- Cano, Z., et al.
(författare)
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GRB 161219B/SN 2016jca : A low-redshift gamma-ray burst supernova powered by radioactive heating
- 2017
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 605
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Tidskriftsartikel (refereegranskat)abstract
- Since the first discovery of a broad-lined type Ic supernova (SN) with a long-duration gamma-ray burst (GRB) in 1998, fewer than fifty GRB-supernovae (SNe) have been discovered. The intermediate-luminosity Swift GRB 161219B and its associated supernova SN 2016jca, which occurred at a redshift of z = 0.1475, represents only the seventh GRB-SN to have been discovered within 1 Gpc, and hence provides an excellent opportunity to investigate the observational and physical properties of these very elusive and rare type of SN. As such, we present optical to near-infrared photometry and optical spectroscopy of GRB 161219B and SN 2016jca, spanning the first three months since its discovery. GRB 161219B exploded in the disk of an edge-on spiral galaxy at a projected distance of 3.4 kpc from the galactic centre. GRB 161219B itself is an outlier in the E-p,E-i - E-gamma,E-iso plane, while SN 2016jca had a rest-frame, peak absolute V-band magnitude of M-V = -19.0 +/- 0.1, which it reached after 12.3 +/- 0.7 rest-frame days. We find that the bolometric properties of SN 2016jca are inconsistent with being powered solely by a magnetar central engine, and demonstrate that it was likely powered exclusively by energy deposited by the radioactive decay of nickel and cobalt into their daughter products, which were nucleosynthesised when its progenitor underwent core collapse. We find that 0.22 +/- 0.08 M-circle dot of nickel is required to reproduce the peak luminosity of SN 2016jca, and we constrain an ejecta mass of 5.8 +/- 0.3 M-circle dot and a kinetic energy of 5.1 +/- 0.8 x 10(52) erg. Finally, we report on a chromatic, pre-maximum bump in the g-band light curve, and discuss its possible origin.
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| 26. |
- Davis-Merry, T. R., et al.
(författare)
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Collective excitations in the transitional nuclei Re-163 and Re-165
- 2015
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 91:3
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Tidskriftsartikel (refereegranskat)abstract
- Excited states in the neutron-deficient nuclei (163)(75) Re-88 and (165)(75) Re-90 were populated in the Cd-106(Ni-60, p2n gamma) and Mo-92(Kr-78, 3p2n gamma) fusion-evaporation reactions at bombarding energies of 270 and 380 MeV, respectively.. rays were detected at the target position using the JUROGAM spectrometer while recoiling ions were separated in-flight by the RITU gas-filled recoil separator and implanted in the GREAT spectrometer. The energy level schemes for Re-163 and Re-165 were identified using recoil-decay correlation techniques. At low spin, the yrast bands of these isotopes consist of signature partner bands based on a single pi h(11/2) quasiproton configuration. The bands display large energy splitting consistent with the soft triaxial shape typical of transitional nuclei above N = 82. The configurations of the excited states are proposed within the framework of the cranked shell model.
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| 27. |
- de Ugarte Postigo, A., et al.
(författare)
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The distribution of equivalent widths in long GRB afterglow spectra
- 2012
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 548, s. A11-
-
Tidskriftsartikel (refereegranskat)abstract
- Context. The extreme brightness of gamma-ray burst (GRB) afterglows and their simple spectral shape make them ideal beacons to study the interstellar medium of their host galaxies through absorption line spectroscopy at almost any redshift. Aims. We describe the distribution of rest-frame equivalent widths (EWs) of the most prominent absorption features in GRB afterglow spectra, providing the means to compare individual spectra to the sample and identify its peculiarities. Methods. Using 69 low-resolution GRB afterglow spectra, we conduct a study of the rest-frame EWs distribution of features with an average rest-frame EW larger than 0.5 angstrom. To compare an individual GRB with the sample, we develop EW diagrams as a graphical tool, and we give a catalogue with diagrams for the 69 spectra. We introduce a line strength parameter (LSP) that allows us to quantify the strength of the absorption features in a GRB spectrum as compared to the sample by a single number. Using the distributions of EWs of single-species features, we derive the distribution of their column densities by a curve of growth (CoG) fit. Results. We find correlations between the LSP and the extinction of the GRB, the UV brightness of the host galaxies and the neutral hydrogen column density. However, we see no significant evolution of the LSP with the redshift. There is a weak correlation between the ionisation of the absorbers and the energy of the GRB, indicating that, either the GRB event is responsible for part of the ionisation, or that galaxies with high-ionisation media produce more energetic GRBs. Spectral features in GRB spectra are, on average, 2.5 times stronger than those seen in QSO intervening damped Lyman-alpha (DLA) systems and slightly more ionised. In particular we find a larger excess in the EW of Civ lambda lambda 1549 relative to QSO DLAs, which could be related to an excess of Wolf-Rayet stars in the environments of GRBs. From the CoG fitting we obtain an average number of components in the absorption features of GRBs of 6.00(-1.25)(+1.00). The most extreme ionisation ratios in our sample are found for GRBs with low neutral hydrogen column density, which could be related to ionisation by the GRB emission.
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| 28. |
- D'Elia, V., et al.
(författare)
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VLT/X-shooter spectroscopy of the GRB 090926A afterglow
- 2010
-
Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 523, s. 36-
-
Tidskriftsartikel (refereegranskat)abstract
- Aims: The aim of this paper is to study the environment and intervening absorbers of the gamma-ray burst GRB 090926A through analyzing optical spectra of its afterglow. Methods: We analyzed medium-resolution spectroscopic observations (R = 10 000, corresponding to 30 km s-1, S/N = 15-30 and wavelength range 3000-25 000) of the optical afterglow of GRB 090926A, taken with X-shooter at the VLT ~22 h after the GRB trigger. Results: The spectrum shows that the ISM in the GRB host galaxy at z = 2.1071 is rich in absorption features, with two components contributing to the line profiles. In addition to the ground state lines, we detect C ii, O i, Si ii, Fe ii, and Ni ii-excited absorption features, which we used to derive information on the distance between the host absorbing gas and the site of the GRB explosion. The distance of component I is found to be 2.40 ± 0.15 kpc, while component II is located far away from the GRB, possibly at ~5 kpc. These values are compatible with those found for other GRBs. The hydrogen column density associated to GRB 090926A is log NH/cm -2 = 21.60 ± 0.07, and the metallicity of the host galaxy is in the range [X/H] = -2.5 to -1.9 with respect to the solar values, i.e., among the lowest values ever observed for a GRB host galaxy. A comparison with galactic chemical evolution models has suggested that the host of GRB090926A is likely to be a dwarf-irregular galaxy. No emission lines were detected, but a Hα flux in emission of 9 × 10-18 erg s-1 cm-2 (i.e., a star-formation rate of 2 M_ȯ yr-1), which is typical of many GRB hosts, would have been detected in our spectra, and thus emission lines are well within the reach of X-shooter. We put an upper limit to the H molecular fraction of the host galaxy ISM, which is f < 7 × 10-7. The continuum has been fitted assuming a power-law spectrum, with a spectral index of β = 0.89-0.02+0.02. The best fit does essentially not require any intrinsic extinction because EB-V < 0.01 mag adopting a SMC extinction curve. Finally, the line of sight of GRB 090926A presents four weak intervening absorption systems in the redshift range 1.24 < z < 1.95. Based on observations collected at the European Southern Observatory, ESO, the VLT/Kueyen telescope, Paranal, Chile, during the science verification phase, proposal code: 060-9427(A).
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| 29. |
- Doncel, Maria, et al.
(författare)
-
Lifetime measurement of the first excited 2(+) state in Te-112
- 2015
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 91:6
-
Tidskriftsartikel (refereegranskat)abstract
- The lifetime of the 2(+) --> 0(g.s.)(+) transition in the neutron-deficicient nucleus Te-112 has been measured for the first time using the DPUNS plunger and the recoil distance Doppler shift technique. The deduced value for the reduced transition probability is B(E2 :0(g.s.)(+) --> 2(+)) = 0.46 +/- 0.04 e(2)b(2), indicating that there is no unexpected enhancement of the B(E2 :0(g.s.)(+) --> 2(+)) values in Te isotopes below the midshell. The result is compared to and discussed in the framework of large-scale shell-model calculations.
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| 30. |
- Doncel, Maria, et al.
(författare)
-
Spin-dependent evolution of collectivity in Te 112
- 2017
-
Ingår i: Physical Review C. - : American Physical Society. - 2469-9985 .- 2469-9993. ; 96:5
-
Tidskriftsartikel (refereegranskat)abstract
- The evolution of collectivity with spin along the yrast line in the neutron-deficient nucleus Te112 has been studied by measuring the reduced transition probability of excited states in the yrast band. In particular, the lifetimes of the 4+ and 6+ excited states have been determined by using the recoil distance Doppler-shift method. The results are discussed using both large-scale shell-model and total Routhian surface calculations.
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| 31. |
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| 32. |
- Ertoprak, Aysegul, et al.
(författare)
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Evidence for octupole collectivity in 172Pt
- 2020
-
Ingår i: European Physical Journal A. - : Springer. - 1434-6001 .- 1434-601X. ; 56:2
-
Tidskriftsartikel (refereegranskat)abstract
- Excited states in the extremely neutron-deficient nucleus 172Pt were populated via 96Ru(78Kr,2p) and 92Mo(83Kr,3n) reactions. The level scheme has been extended up to an excitation energy of ~ 5 MeV and tentative spin-parity assignments up to Iπ = 18+. Linear polarization and angular distribution measurements were used to determine the electromagnetic E1 character of the dipole transitions connecting the positive-parity ground-state band with an excited side-band, firmly establishing it as a negative-parity band. The lowest member of this negative-parity structure was firmly assigned spin-parity 3-. In addition, we observed an E3 transition from this 3- state to the ground state, providing direct evidence for octupole collectivity in 172Pt. Large-scale shell model (LSSM) and total Routhian surface (TRS) calculations have been performed, supporting the interpretation of the 3- state as a collective octupole-vibrational state.
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| 33. |
- Ertoprak, Aysegul, et al.
(författare)
-
Lifetime measurements of core-excited states in semi-magic 95Rh
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Lifetimes of negative-parity states have been determined in the semi-magic (N=50) nucleus 95Rh. The fusion-evaporation reaction 58Ni(40Ca, 3p) was used to populate high-spin states in 95Rh at the Grand Accelerateur National d'Ions Lourds (GANIL) accelerator facility. The results were obtained using the Doppler Shift Attenuation Method (DSAM) based on the Doppler broadened line shapes produced during the slowing down process of the residual nuclei in a thick 6~ mg/cm2 metallic target. B(M1) and B(E2) reduced transition strengths are compared with predictions from large-scale shell-model calculations.
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| 34. |
- Ertoprak, Aysegul, 1987-, et al.
(författare)
-
M1 and E2 transition rates from core-excited states in semi-magic 94Ru
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Lifetimes of high-spin states have been measured in the semi-magic (N=50) nucleus 94Ru. Excited states in 94Ru were populated in the 58Ni(40Ca, 4p)94Ru∗ fusion-evaporation reaction at the Grand Accelerateur National d’Ions Lourds (GANIL) accelerator complex. DSAM lifetime analysis was performed on the Doppler broadened line shapes in energy spectra obtained from γ-rays emitted while the residual nuclei were slowing down in a thick 6 mg/cm2 metallic 58Ni target. In total eight excited-state lifetimes in the angular momentum range I = (13 − 20)ħ have been measured, five of which were determined for the first time. The deduced corresponding B(M1) and B(E2)reduced transition strengths are discussed within the framework of large-scale shell model calculations to study the contribution of different particle-hole configurations, in particular for analyzing contributions from core-excited configurations.
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| 35. |
- Ertoprak, Aysegul, et al.
(författare)
-
M1 and E2 transition rates from core-excited states in semi-magic Ru-94
- 2018
-
Ingår i: European Physical Journal A. - : Springer. - 1434-6001 .- 1434-601X. ; 54:9
-
Tidskriftsartikel (refereegranskat)abstract
- Lifetimes of high-spin states have been measured in the semi-magic (N = 50) nucleus Ru-94. Excited states in Ru-94 were populated in the Ni-58(Ca-40, 4p)Ru-94* fusion-evaporation reaction at the Grand Accelerateur National d'Ions Lourds (GANIL) accelerator complex. DSAM lifetime analysis was performed on the Doppler broadened line shapes in energy spectra obtained from gamma-rays emitted while the residual nuclei were slowing down in a thick 6 mg/cm(2) metallic Ni-58 target. In total eight excited-state lifetimes in the angular momentum range I = (13-20)h have been measured, five of which were determined for the first time. The corresponding B(M1) and B(E2) reduced transition strengths are discussed within the framework of large-scale shell model calculations to study the contribution of different particle-hole configurations, in particular for analyzing contributions from core-excited configurations.
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| 36. |
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| 37. |
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| 38. |
- Frisk, U., et al.
(författare)
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The Odin satellite - I. Radiometer design and test
- 2003
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Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 402:3, s. L27-L34
-
Tidskriftsartikel (refereegranskat)abstract
- The Sub-millimetre and Millimetre Radiometer (SMR) is the main instrument on the Swedish, Canadian, Finnish and French spacecraft Odin. It consists of a 1.1 metre diameter telescope with four tuneable heterodyne receivers covering the ranges 486-504 GHz and 541-581 GHz, and one fixed at 118.75 GHz together with backends that provide spectral resolution from 150 kHz to 1 MHz. This Letter describes the Odin radiometer, its operation and performance with the data processing and calibration described in Paper II.
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| 39. |
- Fynbo, J. P. U., et al.
(författare)
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Low-resolution Spectroscopy of Gamma-ray Burst Optical Afterglows : Biases in the Swift Sample and Characterization of the Absorbers
- 2009
-
Ingår i: Astrophysical Journal Supplement Series. - : American Astronomical Society. - 0067-0049 .- 1538-4365. ; 185:2, s. 526-573
-
Tidskriftsartikel (refereegranskat)abstract
- We present a sample of 77 optical afterglows (OAs) of Swift detected gamma-ray bursts (GRBs) for which spectroscopic follow-up observations have been secured. Our first objective is to measure the redshifts of the bursts. For the majority (90%) of the afterglows, the redshifts have been determined from the spectra. We provide line lists and equivalent widths (EWs) for all detected lines redward of Lyα covered by the spectra. In addition to the GRB absorption systems, these lists include line strengths for a total of 33 intervening absorption systems. We discuss to what extent the current sample of Swift bursts with OA spectroscopy is a biased subsample of all Swift detected GRBs. For that purpose we define an X-ray-selected statistical sample of Swift bursts with optimal conditions for ground-based follow-up from the period 2005 March to 2008 September; 146 bursts fulfill our sample criteria. We derive the redshift distribution for the statistical (X-ray selected) sample and conclude that less than 18% of Swift bursts can be at z > 7. We compare the high-energy properties (e.g., γ-ray (15-350 keV) fluence and duration, X-ray flux, and excess absorption) for three subsamples of bursts in the statistical sample: (1) bursts with redshifts measured from OA spectroscopy; (2) bursts with detected optical and/or near-IR afterglow, but no afterglow-based redshift; and (3) bursts with no detection of the OA. The bursts in group (1) have slightly higher γ-ray fluences and higher X-ray fluxes and significantly less excess X-ray absorption than bursts in the other two groups. In addition, the fractions of dark bursts, defined as bursts with an optical to X-ray slope βOX < 0.5, is 14% in group (1), 38% in group (2), and >39% in group (3). For the full sample, the dark burst fraction is constrained to be in the range 25%-42%. From this we conclude that the sample of GRBs with OA spectroscopy is not representative for all Swift bursts, most likely due to a bias against the most dusty sight lines. This should be taken into account when determining, e.g., the redshift or metallicity distribution of GRBs and when using GRBs as a probe of star formation. Finally, we characterize GRB absorption systems as a class and compare them to QSO absorption systems, in particular the damped Lyα absorbers (DLAs). On average GRB absorbers are characterized by significantly stronger EWs for H I as well as for both low and high ionization metal lines than what is seen in intervening QSO absorbers. However, the distribution of line strengths is very broad and several GRB absorbers have lines with EWs well within the range spanned by QSO-DLAs. Based on the 33 z > 2 bursts in the sample, we place a 95% confidence upper limit of 7.5% on the mean escape fraction of ionizing photons from star-forming galaxies. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile, under programs 275.D-5022 (PI: Chincarini), 075.D-0270 (PI: Fynbo), 077.D-0661 (PI: Vreeswijk), 077.D-0805 (PI: Tagliaferri), 177.A-0591 (PI: Hjorth), 078.D-0416 (PI: Vreeswijk), 079.D-0429 (PI: Vreeswijk), 080.D-0526 (PI: Vreeswijk), 081.A-0135 (PI: Greiner), 281.D-5002 (PI: Della Valle), and 081.A-0856 (PI: Vreeswijk). Also based on observations made with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. Some of the data obtained herein were obtained at the W.M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W.M. Keck foundation.
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| 40. |
- Gaffney, L. P., et al.
(författare)
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Collectivity in the light radon nuclei measured directly via Coulomb excitation
- 2015
-
Ingår i: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:6
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Shape coexistence in heavy nuclei poses a strong challenge to state-of-the-art nuclear models, where several competing shape minima are found close to the ground state. A classic region for investigating this phenomenon is in the region around Z = 82 and the neutron midshell at N = 104. Purpose: Evidence for shape coexistence has been inferred from a-decay measurements, laser spectroscopy, and in-beam measurements. While the latter allow the pattern of excited states and rotational band structures to be mapped out, a detailed understanding of shape coexistence can only come from measurements of electromagnetic matrix elements. Method: Secondary, radioactive ion beams of Rn-202 and Rn-204 were studied by means of low-energy Coulomb excitation at the REX-ISOLDE in CERN. Results: The electric-quadrupole (E2) matrix element connecting the ground state and first excited 2(1)(+) state was extracted for both Rn-202 and Rn-204, corresponding to B(E2; 2(1)(+) -> 0(1)(+)) = 29(-8)(+8) and 43(-12)(+17) W.u., respectively. Additionally, E2 matrix elements connecting the 2(1)(+) state with the 4(1)(+) and 2(2)(+) states were determined in Rn-202. No excited 0(+) states were observed in the current data set, possibly owing to a limited population of second-order processes at the currently available beam energies. Conclusions: The results are discussed in terms of collectivity and the deformation of both nuclei studied is deduced to be weak, as expected from the low-lying level-energy schemes. Comparisons are also made to state-of-the-art beyond-mean-field model calculations and the magnitude of the transitional quadrupole moments are well reproduced.
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| 41. |
- Grahn, T., et al.
(författare)
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Excited states and reduced transition probabilities in Os-168
- 2016
-
Ingår i: PHYSICAL REVIEW C. - : American Physical Society. - 2469-9985. ; 94:4
-
Tidskriftsartikel (refereegranskat)abstract
- The level scheme of the neutron-deficient nuclide Os-168 has been extended and mean lifetimes of excited states have been measured by the recoil distance Doppler-shift method using the JUROGAM gamma-ray spectrometer in conjunction with the IKP Koln plunger device. The 168Os. rays were measured in delayed coincidence with recoiling fusion-evaporation residues detected at the focal plane of the RITU gas-filled separator. The ratio of reduced transition probabilities B(E2; 4(1)(+)-> 2(1)(+))/B(E2; 2(1)(+)-> 0(1)(+)) is measured to be 0.34(18), which is very unusual for collective band structures and cannot be reproduced by interacting boson model (IBM-2) calculations based on the SkM* energy-density functional.
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| 42. |
- Hadinia, Baharak, et al.
(författare)
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Identification of gamma rays from Au-172 and alpha decays of Au-172, Ir-168, and Re-164
- 2009
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 80:6, s. 064310-
-
Tidskriftsartikel (refereegranskat)abstract
- The very neutron deficient odd-odd nucleus Au-172 was studied in reactions of 342 and 348 MeV Kr-78 beams with an isotopically enriched Ru-96 target. The alpha decays previously reported for Au-172 were confirmed and the decay chain extended down to Tm-152 through the discovery of a new alpha-decaying state in Re-164 [E-alpha=5623(10) keV; t(1/2)=864(-110)(+150) ms; b(alpha)=3(1)%]. Fine structure in these alpha decays of Au-172 and Ir-168 were identified. A new alpha-decaying state was also observed and assigned as the ground state in Au-172 [E-alpha=6762(10) keV; t(1/2)=22(-5)(+6) ms]. This decay chain was also correlated down to Tm-152 through previously reported alpha decays. Prompt gamma rays from excited states in Au-172 have been identified using the recoil-decay tagging technique. The partial level scheme constructed for Au-172 indicates that it has an irregular structure. Possible configurations of the alpha-decaying states in Au-172 are discussed in terms of the systematics of nuclei in this region and total Routhian surface calculations.
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| 43. |
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| 44. |
- Harmenberg, U, et al.
(författare)
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Treatment and overall survival (OS) in metastatic renal cell carcinoma (mRCC): A Swedish population-based study (2000-2008).
- 2012
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Ingår i: JOURNAL OF CLINICAL ONCOLOGY. - : American Society of Clinical Oncology (ASCO). - 0732-183X .- 1527-7755. ; 30:5
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- 389 Background: This retrospective register study assessed OS in all mRCC patients in Sweden diagnosed before (2000–2005) and after (2006–2008) the introduction of targeted therapies, plus factors and treatment options influencing OS. Methods: Three Swedish national health registers were used: the Swedish Cancer register (diagnosis and death), the National Patient Register (in-/out-patient data), and the Swedish Prescribed Drug Register. From 2000-2008, 3,243 patients were identified with mRCC; 602 were recorded as receiving 1st-line treatment. Cox proportional hazards regression analysis, including estimation of adjusted OS, was used in three models with the covariates: diagnosis period, age, gender, institution size, nephrectomy status, geographic region (all models); mRCC treatments, defined as any tyrosine kinase inhibitor (TKI; Model 1; n=417); sunitinib (SU), sorafenib (SO), and interferon-alfa (IFN-α) in the 1st-line setting (Model 2; n=602 [SU=244, SO=110, IFN-α=248]); and variations of these drugs as 1st- and 2nd-line treatment sequences (Model 3; n=602). Results: Amongst mRCC patients diagnosed from 2006–2008 compared with 2000–2005, median adjusted OS was 16.1 vs. 10.9 months, respectively (HR=0.76, 95% CI: 0.69, 0.83; P<0.001). In all three models, factors independently associated with significantly improved OS included female gender, large institution, and prior nephrectomy. Prescription of any TKI (Model 1: HR=0.82, 95% CI: 0.73, 0.93; P=0.002) and 1st-line SU treatment (Model 2: HR=0.79, 95% CI: 0.67, 0.94; P=0.007) were associated with significantly improved OS compared with other or no treatments. A similar significant improvement in OS was also confirmed for patients treated with SU only in Model 3; however, due to a low number of observations, the model had insufficient statistical power to be appropriate for all sequences. Conclusions: An improved OS for mRCC patients was demonstrated for the period 2006-2008 compared with 2000-2005. Although the observed survival advantage is multifactorial in origin, contribution of targeted therapies is highly probable. Of the drugs studied, given design limitations, only SU was associated with improved OS.
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| 45. |
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| 46. |
- Hartoog, O. E., et al.
(författare)
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VLT/X-Shooter spectroscopy of the afterglow of the Swift GRB 130606A Chemical abundances and reionisation at z similar to 6
- 2015
-
Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 580
-
Tidskriftsartikel (refereegranskat)abstract
- Context: The reionisation of the Universe is a process that is thought to have ended around z similar to 6, as inferred from spectroscopy of distant bright background sources, such as quasars (QSO) and gamma-ray burst (GRB) afterglows. Furthermore, spectroscopy of a GRB afterglow provides insight in its host galaxy, which is often too dim and distant to study otherwise.Aims: For the Swift GRB 130606A at z = 5.913 we have obtained a high S/N spectrum covering the full optical and near-IR wavelength region at intermediate spectral resolution with VLT/X-Shooter. We aim to measure the degree of ionisation of the intergalactic medium (IGM) between z = 5.02-5.84 and to study the chemical abundance pattern and dust content of its host galaxy.Methods: We estimated the UV continuum of the GRB afterglow using a power-law extrapolation, then measured the flux decrement due to absorption at Ly alpha,beta, and gamma wavelength regions. Furthermore, we fitted the shape of the red damping wing of Lya. The hydrogen and metal absorption lines formed in the host galaxy were fitted with Voigt profiles to obtain column densities. We investigated whether ionisation corrections needed to be applied.Results: Our measurements of the Ly alpha-forest optical depth are consistent with previous measurements of QSOs, but have a much smaller uncertainty. The analysis of the red damping wing yields a neutral fraction x(HI) < 0.05 (3 sigma). We obtain column density measurements of H, Al, Si, and Fe; for C, O, S and Ni we obtain limits. The ionisation due to the GRB is estimated to be negligible (corrections < 0.03 dex), but larger corrections may apply due to the pre-existing radiation field (up to 0.4 dex based on sub-DLA studies). Assuming that [Si/Fe] = +0.79 +/- 0.13 is due to dust depletion, the dust-to-metal ratio is similar to the Galactic value.Conclusions: Our measurements confirm that the Universe is already predominantly ionised over the redshift range probed in this work, but was slightly more neutral at z > 5.6. GRBs are useful probes of the ionisation state of the IGM in the early Universe, but because of internal scatter we need a larger statistical sample to draw robust conclusions. The high [Si/Fe] in the host can be due to dust depletion, a-element enhancement, or a combination of both. The very high value of [Al/Fe] = 2.40 +/- 0.78 might be due to a proton capture process and is probably connected to the stellar population history. We estimate the host metallicity to be -1.7 < [M/H] < -0.9 (2%-13% of solar).
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| 47. |
- Hedlund, Johanna S. U., et al.
(författare)
-
Long-term phenological shifts and intra-specific differences in migratory change in the willow warbler Phylloscopus trochilus
- 2015
-
Ingår i: Journal of Avian Biology. - : Wiley. - 0908-8857 .- 1600-048X. ; 46:1, s. 97-106
-
Tidskriftsartikel (refereegranskat)abstract
- Climate change can influence many aspects of avian phenology and especially migratory shifts and changes in breeding onset receive much research interest in this context. However, changes in these different life-cycle events in birds are often investigated separately and by means of ringing records of mixed populations. In this long-term study on the willow warbler Phylloscopus trochilus, we investigated timing of spring and autumn migration in conjunction with timing of breeding. We made distinction among individuals with regard to age, sex, juvenile origin and migratory phase. The data set comprised 22-yr of ringing records and two temporally separated data sets of egg-laying dates and arrival of the breeding population close to the ringing site. The results reveal an overall advancement consistent in most, but not all, phenological events. During spring migration, early and median passage of males and females became earlier by between 4.4 to 6.3 d and median egg-laying dates became earlier by 5 d. Male arrival advanced more, which may lead to an increase in the degree of protandry in the future. Among breeding individuals, only female arrival advanced in timing. In autumn, adults and locally hatched juvenile females did not advanced median passage, but locally hatched juvenile males appeared 4.2 d earlier. Migrating juvenile males and females advanced passage both in early and median migratory phase by between 8.4 to 10.1 d. The dissimilarities in the response between birds of different age, sex and migratory phase emphasize that environmental change may elicit intra-specific selection pressures. The overall consistency of the phenological change in spring, autumn and egg-laying, coupled with the unchanged number of days between median spring and autumn migration in adults, indicate that the breeding area residence has advanced seasonally but remained temporally constant.
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| 48. |
- Hedlund, Johanna S. U., et al.
(författare)
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Point of no return – absence of returning birds in the otherwise philopatric willow warbler Phylloscopus trochilus
- 2017
-
Ingår i: Journal of Avian Biology. - : Wiley. - 0908-8857 .- 1600-048X. ; 48:3, s. 399-406
-
Tidskriftsartikel (refereegranskat)abstract
- The return of individual birds to a specific area in successional years, i.e. philopatry, is a remarkable behavioural trait. Here we report on the remarkably reversed: the complete absence of returning individuals of a migratory passerine with otherwise pronounced philopatry. At a high latitude study site in Abisko (68°32ʹN, 18°80ʹE) in northern Sweden none of the banded adult willow warblers Phylloscopus trochilus returned to breed 2011–2014. This is in stark contrast to all other reports in the literature and also to our two southern study sites (at 56°56ʹN, 18°10ʹE and at 58°94ʹN, 17°14ʹE) where 18–38% of adults returned. We investigated this aberrant pattern found in Abisko by analysing three parameters known to influence philopatry; nest predation, breeding success and breeding density, and predicted that absence of philopatry should co-occur with low breeding success, low breeding density and/or high nest predation. The results did not corroborate this, except that breeding density was lower at Abisko (49–71 pairs km–2) than at the southern sites (106 pairs km–2, 101 pairs km–2). Instead, we suggest the hypothesis that the absence of philopatry is caused by an influx of southern, dispersal-prone individuals deploying another breeding strategy and that this intra-specific range expansion is enabled by milder climate and low population density.
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| 49. |
- Holland, Stephen T., et al.
(författare)
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GRB 090417B and its host galaxy : a step toward an understanding of optically dark gamma-ray bursts
- 2010
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Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 717:1, s. 223-234
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Tidskriftsartikel (refereegranskat)abstract
- GRB 090417B was an unusually long burst with a T-90 duration of at least 2130 s and a multi-peaked light curve at energies of 15-150 keV. It was optically dark and has been associated with a bright star-forming galaxy at a redshift of 0.345 that is broadly similar to the Milky Way. This is one of the few cases where a host galaxy has been clearly identified for a dark gamma-ray burst (GRB) and thus an ideal candidate for studying the origin of dark bursts. We find that the dark nature of GRB 090417B cannot be explained by high redshift, incomplete observations, or unusual physics in the production of the afterglow. Assuming the standard relativistic fireball model for the afterglow we find that the optical flux is at least 2.5 mag fainter than predicted by the X-ray flux. The Swift/XRT X-ray data are consistent with the afterglow being obscured by a dense, localized sheet of dust approximately 30-80 pc from the burst along the line of sight. Our results suggest that this dust sheet imparts an extinction of A(V) greater than or similar to 12 mag, which is sufficient to explain the missing optical flux. GRB 090417B is an example of a GRBs that is dark due to the localized dust structure in its host galaxy.
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- Jaderstrom, H., et al.
(författare)
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200 and 300 MeV/nucleon nuclear reactions responsible for single-event effects in microelectronics
- 2008
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 77:4, s. 44601-
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Tidskriftsartikel (refereegranskat)abstract
- An experimental study of nuclear reactions between Si-28 nuclei at 200 and 300 MeV/nucleon and hydrogen or deuterium target nuclei was performed at the CELSIUS storage ring in Uppsala, Sweden, to collect information about the reactions responsible for single-event effects in microelectronics. Inclusive data on Si-28 fragmentation, as well as data on correlations between recoils and spectator protons or alpha particles are compared to predictions from the Dubna cascade model and the Japan Atomic Energy Research Institute version of the quantum molecular dynamics model. The comparison shows satisfactory agreement for inclusive data except for He fragments where low-energy sub-barrier fragments and recoiling fragments with very large momenta are produced much more frequently than predicted. The yield of exclusive data are also severely underestimated by the models whereas the charge distributions of recoils in these correlations compare well. The observed enhancement in He emission, which may well be important for the description of single-event effects, is most likely to be attributed to alpha clustering in Si-28 nuclei.
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