| 1. |
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| 2. |
- Ekelin, Svante, et al.
(författare)
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Real-Time Measurement of End-to-End Available Bandwidth using Kalman Filtering
- 2006
-
Ingår i: 10th IEEE/IFIP Network Operations and Management Symposium, 2006. NOMS 2006.. - Piscataway, New Jersey, USA : IEEE Computer Society. - 1424401429 - 9781424401420 ; , s. 73-84
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Konferensbidrag (refereegranskat)abstract
- This paper presents a new method, BART (bandwidth available in real-time), for estimating the end-to-end available bandwidth over a network path. It estimates bandwidth quasi-continuously, in real-time. The method has also been implemented as a tool. It relies on self-induced congestion, and repeatedly samples the available bandwidth of the network path with sequences of probe packet pairs, sent at randomized rates. BART requires little computation in each iteration, is lightweight with respect to memory requirements, and adds only a small amount of probe traffic. The BART method uses Kalman filtering, which enables real-time estimation (a.k.a. tracking). It maintains a current estimate, which is incrementally improved with each new measurement of the inter-packet time separations in a sequence of probe packet pairs. The measurement model has a strong non-linearity, and would not at first sight be considered suitable for Kalman filtering, but we show how this non-linearity can be handled. BART may be tuned according to the specific needs of the measurement application, such as agility vs. stability of the estimate. We have tested an implementation of BART in a physical test network with carefully controlled cross traffic, with good accuracy and agreement. Test measurements have also been performed over the Internet. We compare the performance of BART with that of pathChirp, a state-of-the-art tool for measuring end-to-end available bandwidth in real-time
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| 3. |
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| 4. |
- Ekelin, Svante, et al.
(författare)
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Real-time measurement of end-to-end available bandwidth using Kalman filtering
- 2006. - 1
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Konferensbidrag (refereegranskat)abstract
- This paper presents a new method, BART (Bandwidth Available in Real-Time), for estimating the end-to-end available bandwidth over a network path. It estimates bandwidth quasi-continuously, in real-time. The method has also been implemented as a tool. It relies on self-induced congestion, and probes the network path with trains of probe packets, sent at randomized rates. BART requires little computation in each iteration, is light-weight with respect to memory requirements, and adds only a small amount of probe traffic. The BART method is based on Kalman filtering, which enables real-time estimation (a.k.a. tracking) with optimum performance under general conditions. It maintains a current estimate, which is incrementally improved with each new measurement of the inter-packet time separations in a probe packet train. The measurement model has a strong non-linearity, and would not at first sight be considered suitable for Kalman filtering, but we show how this non-linearity can be handled. BART may be tuned according to the specific needs of the measurement application, such as agility vs. stability of the estimate, and the desired time-scale on which to track traffic fluctuations. We have tested BART in a physical test network with carefully controlled cross traffic, with good accuracy and agreement. Test measurements have also been performed over the Internet. We compare the performance of BART with that of pathChirp, a state-of-the-art tool for measuring end-to-end available bandwidth in real-time.
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| 5. |
- Johnsson, Jan-Erik, et al.
(författare)
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Modeling N2O Reduction and Decomposition in a Circulating Fluidized Bed Boiler
- 1996
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Ingår i: Energy & Fuels. - 1520-5029 .- 0887-0624. ; 10:4, s. 970-979
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Tidskriftsartikel (refereegranskat)abstract
- The N2O concentration was measured in a circulating fluidized bed boiler of commercial size. Kinetics for N2O reduction by char and catalytic reduction and decomposition over bed material from the combustor were determined in a laboratory fixed bed reactor. The destruction rate of N2O in the combustion chamber and the cyclone was calculated taking three mechanisms into account: reduction by char, catalytic decomposition over bed material, and thermal decomposition. The calculated destruction rate was in good agreement with the measured destruction of N2O injected at different levels in the boiler. The conclusion is that in the bottom part of the combustor, where the solids concentration is about 1000 kg/m3 (voidage 0.6) and the char content in solids 2 wt %, heterogeneous reactions were the most important N2O destruction mechanisms. Reduction by char accounted for 80% of the N2O destruction, 20% was due to catalytic decomposition over bed material, and homogeneous thermal decomposition was negligible. However, at higher levels in the combustor, the solids concentration is lower: at the top 60% of the N2O destruction was due to thermal decomposition and in the cyclone heterogeneous destruction of N2O was insignificant. It was estimated that more than one-half of the formation of N2O in the combustion chamber takes place above the secondary air inlet.
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| 6. |
- Johnsson, Jan-Erik, et al.
(författare)
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Modelling of N2O reduction in a circulating fluidized bed boiler
- 1996
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Ingår i: Proc of the 5th International Conference on Circulating Fluidized Bed. ; 5, s. 338-343
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Konferensbidrag (refereegranskat)abstract
- The N2O was measured in a circulating fluidized bed boiler of commercial size. Kinetics of N2O reduction and decomposition by char and over bed material from the combustor were determined in a laboratory fixed bed reactor. A mathematical model of the N2O chemistry in the combustor was set up, and the results from the simulation of N2O destruction were in good agreement with measurements of the N2O destruction from injection at different levels in the furnace of the boiler.
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| 7. |
- Johnsson, Jan-Erik, et al.
(författare)
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Modelling of NOx Formation in a Circulating Fluidized Bed Boiler
- 1990
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Ingår i: Proceedings 3rd International Conference on Circulating Fluidized Beds held October 15-18, 1990 in Nagoya, Japan.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A detailed kinetic model for the oxidation of NH3 and reduction of NO in FBC is used to model the NO concentration profile in an 8 MW CFB. Three different fuels were burned in the full scale tests: Bituminous coal, brown coal and petroleum coke. Kinetics were measured in a laboratory reactor using samples of char and bed material from the boiler. The simulation results show that char is an important catalyst for the oxidation of NH3 and reduction of NO when burning bituminous coal and petroleum coke. The char content in the brown coal bed is low and very active bed material with a high ash content is the important catalyst in this case. Homogeneous gas phase reactions were found to have only a minor influence. The levels of NO concentration calculated are in agreement with the experimental results. It is concluded that modelling the fuel-N conversion using kinetics measured for the specific chars and bed materials is a considerable step towards a better understanding of the formation and reduction of NO in FBC.
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| 8. |
- Persson, Jan, 1962, et al.
(författare)
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Fully covered stents are similar to semi-covered stents with regard to migration in palliative treatment of malignant strictures of the esophagus and gastric cardia : results of a randomized controlled trial.
- 2017
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Ingår i: Surgical Endoscopy. - : Springer Science and Business Media LLC. - 0930-2794 .- 1432-2218. ; 31:10, s. 4025-4033
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Stent migration is a significant clinical problem in palliation of malignant strictures in the esophagus and gastro-esophageal junction (GEJ). We have compared a newer design of a fully-covered stent to a widely used semi-covered stent using migration >20 mm as the primary outcome variable. Effects on dysphagia, quality of life (QoL) and re-intervention frequency were also investigated.METHODS: Patients with dysphagia due to non-curable esophagus/GEJ cancer were randomized to receive either a more recent design of a fully-covered stent (n = 48) or a conventional semi-covered stent (n = 47). Chest x-ray, dysphagia and QoL were studied at baseline, one week, four weeks and three months thereafter.RESULTS: There were no significant differences either in stent migration distance or in the migration frequency. Stent migration during the total study period occurred in 37.2 % in the semi-covered group compared to 20.0 % for the fully-covered group. Dysphagia was measured with Watson and Ogilvie scores and with the dysphagia module in the QoL scale (QLQ-OG25). On average, there was a tendency to better dysphagia relief for the fully-covered design as scored with the two latter dysphagia instruments (p= 0.081 and p= 0.067) at three months and towards more re-interventions in the semi-covered group (p= 0.083).CONCLUSION: In spite of its somewhat lower intrinsic radial force, the fully-covered stent was comparable to the conventional semi-covered stent with regard to stent migration. The data further suggest a potential benefit of the fully-covered stent in improving dysphagia in patients with longer life expectancy.
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| 9. |
- Alvarsson Jan-Åke, Agüero Oscar, Bretschneider Peter, Brunius Staffan, Gumucio Juan Carlos, Gurt Carl-Johan, Hultkrantz Åke, Isacsson Sven-Erik, Johnsson Mick, Kurkiala Mikael, Liljefors-Persson Bodil, Perruchon Marie & Århem Kaj
(författare)
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Amerikas indiankulturer
- 1997
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Bok (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Astermark, Jan, et al.
(författare)
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Blödarsjuka med HIV. Långsammare infektionsförlopp hos yngre och vid större förbrukning av faktorkoncentrat
- 1998
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Ingår i: Läkartidningen. - 0023-7205. ; 95:1, s. 48-50
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Tidskriftsartikel (refereegranskat)abstract
- HIV disease progression and the effect of replacement therapy with clotting factor concentrates (CFCs) were studied in 100 Swedish haemophiliacs, mean age at seroconversion 29 years (range, 4-72). On average 16 years after seroconversion, 67 per cent of the patients had CD4+ cell counts of < 200 x 10(6)/l, 50 per cent had developed AIDS, and 58 per cent had died. HIV disease progression was significantly slower in those aged less than 28 (median age) at seroconversion (P = 0.004). Moreover, mortality was inversely correlated to total annual CFC consumption after adjustment for age and HIV-related therapy, i.e., Pneumocystis carinii prophylaxis and antiretroviral drugs (P = 0.014), but unrelated to the purity of the CFCs used. After adjustment for age, annual CFC consumption and HIV-therapy, prophylactic replacement therapy was not associated with significantly better survival than on-demand treatment. It is concluded that in HIV-positive haemophiliacs replacement therapy may have a beneficial effect on the immune system, and that CFC purity and the regimen (prophylaxis vs on-demand) would seem to be factors of minor importance.
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| 11. |
- Bergquist, Henrik, 1969, et al.
(författare)
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Combined stent insertion and single high-dose brachytherapy in patients with advanced esophageal cancer - results of a prospective safety study.
- 2011
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Ingår i: Diseases of the esophagus. - : Oxford University Press (OUP). - 1442-2050 .- 1120-8694. ; Early View
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Tidskriftsartikel (refereegranskat)abstract
- Previous randomized studies comparing the two commonly used palliative treatments for incurable esophageal cancer, i.e. stent insertion and intraluminal brachytherapy, have revealed the pros and cons of each therapy. While stent treatment offers a more prompt effect, brachytherapy results in more long-lasting relief of dysphagia and a better health-related quality of life (HRQL) in those living longer. This prospective pilot study aimed to explore the feasibility and safety of combining these two regimes and incorporating a single high dose of internal radiation. Patients with newly diagnosed, incurable cancer of the esophagus and dysphagia were eligible for inclusion, and stent insertion followed by a single dose (12Gy) of brachytherapy was performed as a two-stage procedure. Clinical parameters including HRQL and adverse events were registered at inclusion, and 1, 2, 3, 6, and 12 months later. Twelve patients (nine males) with a median age of 73 years (range 54-85) were included. Stent insertion followed by a single dose of brachytherapy was successfully performed in all but one patient who was treated with stent only. Relief of dysphagia was achieved in the majority of cases (10/11, P < 0.05), but HRQL did not improve except for dysphagia-related items. Only minor adverse events, including chest pain, reflux, and restenosis, were reported. The median survival time after inclusion was 6.6 months. Our conclusion is that the combination of stent insertion and single high-dose brachytherapy seems to be a feasible and safe palliative regime in patients with advanced esophageal cancer. Randomized trials comparing the efficacy of this strategy to stent insertion or brachytherapy alone are warranted.
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| 12. |
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| 13. |
- Bohgard, Mats, et al.
(författare)
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Nu krävs satsning på forskning för ett hållbart arbetsliv
- 2021
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Ingår i: Dagens Medicin. - 1104-7488.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Debatt: Vi vill att forskningsråden skapar tvärvetenskapliga regionala forskningscentrum för arbetslivsforskning, som är internationellt konkurrenskraftiga och ger nationellt och regionalt kunskapsstöd. Dessa centrum ska ge kunskaper för både befintliga och framtida utmaningar. Stora vinster kan fås om forskning om folkhälsa och yttre miljö samordnas i centrumen. Arbetslivet är grunden för hälsa, välstånd och ett välfungerande samhälle. För att säkra att framtidens arbetsliv bidrar till hälsa och välstånd behövs både kunskap om hur det ska utformas och en uthållig infrastruktur för forskning. Tyvärr saknas detta. Gammal kunskap faller i glömska.
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| 14. |
- Cromvik, Julia, 1980, et al.
(författare)
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Eosinophils in the blood of hematopoietic stem cell transplanted patients are activated and have different molecular marker profiles in acute and chronic graft-versus-host disease.
- 2014
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Ingår i: Immunity, inflammation and disease. - : Wiley. - 2050-4527. ; 2:2, s. 99-113
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Tidskriftsartikel (refereegranskat)abstract
- While increased numbers of eosinophils may be detected in patients with graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation, it is not known if eosinophils play a role in GVHD. The aims of this study were to determine: whether eosinophils are activated during GVHD; whether the patterns of activation are similar in acute and chronic GVHD; and the ways in which systemic corticosteroids affect eosinophils. Transplanted patients (n = 35) were investigated for eosinophil numbers and the expression levels of 16 eosinophilic cell surface markers using flow cytometry; all the eosinophil data were analyzed by the multivariate method OPLS-DA. Different patterns of molecule expression were observed on the eosinophils from patients with acute, chronic, and no GVHD, respectively. The molecules that provided the best discrimination between acute and chronic GVHD were: the activation marker CD9; adhesion molecules CD11c and CD18; chemokine receptor CCR3; and prostaglandin receptor CRTH2. Patients with acute or chronic GVHD who received systemic corticosteroid treatment showed down-regulation of the cell surface markers on their eosinophils, whereas corticosteroid treatment had no effect on the eosinophil phenotype in the patients without GVHD. In summary, eosinophils are activated in GVHD, display different activation profiles in acute and chronic GVHD, and are highly responsive to systemic corticosteroids.
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| 15. |
- Dacasa, Hugo, et al.
(författare)
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Single-shot extreme-ultraviolet wavefront measurements of high-order harmonics
- 2019
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Ingår i: Optics Express. - 1094-4087. ; 27:3, s. 2656-2670
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Tidskriftsartikel (refereegranskat)abstract
- We perform wavefront measurements of high-order harmonics using an extreme-ultraviolet (XUV) Hartmann sensor and study how their spatial properties vary with different generation parameters, such as pressure in the nonlinear medium, fundamental pulse energy and duration as well as beam size. In some conditions, excellent wavefront quality (up to 휆/11) was obtained. The high throughput of the intense XUV beamline at the Lund Laser Centre allows us to perform single-shot measurements of both the full harmonic beam generated in argon and individual harmonics selected by multilayer mirrors. We theoretically analyze the relationship between the spatial properties of the fundamental and those of the generated high-order harmonics, thus gaining insight into the fundamental mechanisms involved in high-order harmonic generation (HHG).
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| 16. |
- Engström, Gunnar, et al.
(författare)
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The Swedish CArdioPulmonary BioImage Study : objectives and design
- 2015
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 278:6, s. 645-659
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Tidskriftsartikel (refereegranskat)abstract
- Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started.
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| 17. |
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| 18. |
- Hyltander, Anders, 1954, et al.
(författare)
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Supportive nutrition on recovery of metabolism, nutritional state, health-related quality of life, and exercise capacity after major surgery: a randomized study
- 2005
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Ingår i: Clinical gastroenterology and hepatology. - 1542-3565. ; 3:5, s. 466-74
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND & AIMS: The aim of this study was to investigate whether specialized supportive enteral and parenteral feeding have superior effects compared to oral nutrition on recovery during long-term postoperative treatment of cancer patients with preoperative weight loss and reduced maximum exercise capacity. METHODS: One hundred twenty-six patients referred for resection of the esophagus (n = 48), stomach (n = 28), or pancreas (n = 50) were considered to be included before operation. Included patients (n = 80) received supportive enteral or parenteral nutrition postoperatively at home corresponding to 1000 kcal/d until the patients did not wish to continue with artificial nutrition for any reason. Patients randomized to oral nutrition only served as control subjects. Caloric intake, body composition (dual-energy x-ray absorptiometry), and respiratory gas exchanges at rest and during exercise were measured including health-related quality of life. RESULTS: Survival and hospital stay did not differ among the groups, whereas overall complications were higher on artificial nutrition (P < .05). Changes in resting energy expenditure and biochemical tests did not differ during follow-up among the groups. Body weight and whole body fat declined similarly over time in all groups (P < .005), whereas lean body mass was unchanged during follow-up compared to preoperative values. Maximum exercise capacity and maximum oxygen consumption were normalized within 6 months postoperatively in all groups. There was no difference in recovery of food intake among the groups. Parenteral feeding was associated with the highest rate of nutrition-related complications, whereas enteral feeding reduced quality of life most extensively. CONCLUSION: After major surgery, specialized supportive enteral and parenteral nutrition are not superior to oral nutrition only when guided by a dietitian.
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| 19. |
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| 20. |
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| 21. |
- Persson, Jan, 1962, et al.
(författare)
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Treatment of Achalasia with Laparoscopic Myotomy or Pneumatic Dilatation: Long-Term Results of a Prospective, Randomized Study
- 2015
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Ingår i: World Journal of Surgery. - : Springer Science and Business Media LLC. - 0364-2313 .- 1432-2323. ; 39:3, s. 713-720
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Tidskriftsartikel (refereegranskat)abstract
- Abstract BACKGROUND: This study compares the long-term results of pneumatic dilatations versus laparoscopic myotomy using treatment failure as the primary outcome. The frequency and degree of dysphagia, the effects on quality of life (QoL), and health economy were also examined. METHODS: Fifty-three patients with achalasia were randomized to laparoscopic myotomy with a posterior partial fundoplication [laparoscopic myotomy (LM) n = 25] or repetitive pneumatic dilatation [pneumatic dilatation (PD) n = 28]. The median observation period was 81.5 months (range 12-131). RESULTS: At the minimal follow-up of 5 years, ten patients (36 %) in the dilatation group and two patients (8 %) in the myotomy group, including two patients lost to follow-up (one in each arm), were classified as failures (p = 0.016). The cumulative incidence of treatment failures was analyzed by survival statistics. Taking the entire follow-up period into account, a significant difference was observed in favor of the LM strategy (p = 0.02). Although both treatments resulted in significant improvements in dysphagia scores, LM was significantly favored over PD after 1 and 3 years, but not after 5 years. Health-related QoL assessed by the personal general well being score was higher in the LM group after 3 years, but the difference was not fully statistically significant at 5 years. Direct medical costs during the entire follow-up period were in median $13,421 for LM as compared to $5,558 for PD (p = 0.001). CONCLUSIONS: This long-term follow-up of a randomized clinical study shows that LM is superior to repetitive PD treatment of newly diagnosed achalasia, albeit that this surgical strategy is burdened by high initial direct medical costs. www.ClinicalTrials.gov NCT 02086669.
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| 22. |
- Persson, Jan, 1962, et al.
(författare)
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Validation of instruments for the assessment of dysphagia due to malignancy of the esophagus
- 2019
-
Ingår i: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. - : Oxford University Press (OUP). - 1442-2050. ; 32:9
-
Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to validate the Watson scale, the Ogilvie scale, and the Goldschmid scale for assessment of dysphagia due to malignancy of the esophagus. After translation of the scales to Swedish, 35 patients with dysphagia due to esophageal malignancy were asked to participate. On day 1, patients were asked to fill in the questionnaires. The patients also kept a food diary for 4 consecutive days, for assessment of actual swallowing ability. On day 10, the patients were asked to fill in the scales again, to control for individual variability. As an external control group, 29 healthy volunteers were asked to fill in the questionnaires once. External validation was done against actual swallowing ability, and against the European Organization for Research and Treatment of Cancer scales QLQ-C30 and QLQ-OG25, which are already validated quality of life scales for malignancy. Reliability in the categorical variables (Ogilvie and Goldschmid) showed weighted kappa values of 0.52 and 0.54, respectively. For the Watson scale and the Dysphagia module of QLQ-OG25, the intraclass correlation coefficients were 0.68 and 0.80, respectively. Correlations between all scales were good to excellent with values of correlation coefficients (rs) between 0.69 and 0.88, with the strongest correlations between the Ogilvie score and the dysphagia module in QLQ-OG25. These latter two scales had the strongest correlation to the food diary (rs = 0.72). Although the Ogilvie scale was superior, all the three scales showed good reliability and are thus judged to have good validity for assessment of dysphagia due to esophageal malignancy. © The Author(s) 2018. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
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| 23. |
- Sanchez-Gonzalez, A., et al.
(författare)
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Auger electron and photoabsorption spectra of glycine in the vicinity of the oxygen K-edge measured with an X-FEL
- 2015
-
Ingår i: Journal of Physics B-Atomic Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 48:23
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Tidskriftsartikel (refereegranskat)abstract
- We report the first measurement of the near oxygen K-edge auger spectrum of the glycine molecule. Our work employed an x-ray free electron laser as the photon source operated with input photon energies tunable between 527 and 547 eV. Complete electron spectra were recorded at each photon energy in the tuning range, revealing resonant and non-resonant auger structures. Finally ab initio theoretical predictions are compared with the measured above the edge auger spectrum and an assignment of auger decay channels is performed.
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| 24. |
- Sediqi, Ehsan, et al.
(författare)
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Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up
- 2021
-
Ingår i: Surgical Endoscopy. - : Springer Science and Business Media LLC. - 0930-2794 .- 1432-2218. ; 35, s. 1618-1625
-
Tidskriftsartikel (refereegranskat)abstract
- Background and objectives: The most efficient long-term treatment strategy for achalasia has yet to be established. This study compared the long-term results (≥ 10years) after either pneumatic dilatations or laparoscopic myotomy using treatment failure as the primary outcome. Secondary objectives were; the frequency and degree of dysphagia and effects on health-related quality of life (QoL). Patients and methods: Out of the 53 patients with achalasia who were initially randomized to either laparoscopic myotomy with a posterior partial fundoplication (LM) or repetitive pneumatic dilatation (PD), 43 remained for scrutiny after a median observation period of 170months (LM; n = 20 and PD; n = 23). Results: At the follow-up of 60months, 10 patients (36%) in the PD group and two patients (8%) in the LM group were classified as treatment failures (p = 0.016). At the latest follow-up time point (≥ 10years), the corresponding numbers were 13 (57%) and 4 (20%), respectively. The Kaplan–Meier analysis of the cumulative incidence of treatment failure revealed a significant advantage of LM over the dilatation strategy (p = 0.036)). QoL assessed by the generic instrument PGWB and the more disease-specific instrument GSRS revealed scores which were similar in the two study groups with no obvious changes over time. Reflux was better controlled in the LM group (p = 0.02 regarding PPI consumption). Conclusions: After more than a decade of follow-up, laparoscopic myotomy reinforces its superiority over repetitive pneumatic dilatation treatment strategy in the management of newly diagnosed achalasia. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
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| 25. |
- Vikgren, Jenny, 1957, et al.
(författare)
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Visual and Quantitative Evaluation of Emphysema: A Case-Control Study of 1111 Participants in the Pilot Swedish CArdioPulmonary BioImage Study (SCAPIS)
- 2020
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Ingår i: Academic Radiology. - : Elsevier BV. - 1076-6332 .- 1878-4046. ; 27:5, s. 636-643
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Tidskriftsartikel (refereegranskat)abstract
- Rationale and Objectives: Emphysema is a hallmark of chronic obstructive pulmonary disease. The primary aim of this study was to investigate inter- and intraobserver agreement of visual assessment of mild emphysema in low-dose multidetector computed tomography of subjects in the pilot SCAPIS in order to certify consistent detection of mild emphysema. The secondary aim was to investigate the performance of quantitative densitometric measurements in the cohort. Materials and Methods: Participants with emphysema (n = 100, 56 males and 44 females) reported in the electronic case report form of pilot SCAPIS and 100 matched controls (gender, age, height, and weight) without emphysema were included. To assess interobserver variability the randomized examinations were evaluated by two thoracic radiologists. For intraobserver variability three radiologists re-evaluated randomized examinations which they originally evaluated. The results were evaluated statistically by Krippendorff's α. The dataset was also assessed quantitively for % lung attenuation value −950 HU (LAV950), mean lung density and total lung volume by commercially available software. Results: Emphysema was visually scored as mild and Krippendorff's α was ≥0.8 for both the inter- and intraobserver agreement regarding presence of emphysema and approaching 0.8 regarding presence and extent of emphysema by location in the upper lobes. Mean LAV950 was not different between the emphysematous and the nonemphysematous participants; 8.3% and 8.4%, respectively. Conclusion: The inter- and intraobserver agreement for visual detection of mild emphysema in low-dose multidetector computed tomography was good. Surprisingly, quantitative analysis could not reliably identify participants with mild emphysema, which hampers the use of automatic evaluation. © 2019 The Association of University Radiologists
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| 26. |
- Wang, Chuan, et al.
(författare)
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A model on CO2 emission reduction in integrated steelmaking by optimization methods
- 2008
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Ingår i: International Journal of Energy Research. - : Hindawi Limited. - 0363-907X .- 1099-114X. ; 32:12, s. 1092-1106
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Tidskriftsartikel (refereegranskat)abstract
- The iron and steel industry is a large energy user in the manufacturing sector. Carbon dioxide from the steel industry accounts for about 5-7% of the total anthropogenic CO2 emission. Concerns about energy consumption and climate change have been growing on the sustainability agenda of the steel industry. The CO2 emission will be heavily influenced with increasing steel production in the world. It is of great interest to evaluate and decrease the specific CO2 emission and to find out feasible solutions for its reduction. In this work, a process integration method focusing on the integrated steel plant system has been applied. In this paper, an optimization model, which can be used to evaluate CO2 emission for the integrated steel plant system, is presented. Two application cases of analysing CO2 emission reduction possibilities are included in the paper. Furthermore, the possibility to apply the model for a specific integrated steel plant has been discussed. The research work on the optimization of energy and CO2 emission has shown that it is possible to create a combined optimization tool that is powerful to assess the system performance from several aspects for the steel plant.
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| 27. |
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